PROJECT REPORT SUBMITTED IN FULFILLMENT OF THE REQUIREMENT FOR THE COURSE STANDARDISATION OF HERBAL DRUGS AND COSMETICS (PHR-

805 A ) OF UTTARAKHAND TECHNICAL UNIVERSITY, DEHRADUN

BACHELOR OF PHARMACY
Submitted by:

PRABHJOT KAUR 09270300043

2009-2013 Under the Guidance of

DR. S.K.DUBEY DEPARTMENT OF PHARMACEUTICAL SCIENCES

DEPARTMENT OF PHARMACEUTICAL SCIENCES SARDAR BHAGWAN SINGH POST GRADUATE INSTITUTE OF BIOMEDICAL SCIENCES & RESEARCH BALAWALA, DEHRADUN-248161, UTTARAKHAND ( 2012-2013 )

Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences and Research
Under the aegis of Gaurav Bharti Shiksha Sansthan, Balawala, Dehradun
Balawala, Dehardun- 248 161, Uttarakhand, India. Tel: 91-135-2685753, 2686286, Fax:2686286. E-mail: sbspgi@gmail.com Website: www.sbspgi.edu.in
Approved by AICTE., New Delhi, PCI, New Delhi and affiliated to Uttarakhand Technical University, Dehradun

Date:..

CERTIFICATE
This is to certify that the work embodied in this Project entitled Isolation of

curcuminoids from turmeric of different regions was carried out by

Miss.Prabhjot Kaur under my direct supervision. I have checked the Project and affirm that this Project meets the requirements of B.Pharm. course of Uttarakhand Technical University, Dehradun. I recommend the submission of Project. Date: Place: Balawala, Dehradun Dr. S.K. Dubey Associate. Proffessor Department of Pharmaceutical Sciences

APPROVED FOR SUBMISSION Dr. Vikas Anand Project Coordinator

Prof. (Dr.) Veerma Ram (H.O.D.)

Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences and Research
Under the aegis of Gaurav Bharti Shiksha Sansthan, Balawala, Dehradun
Balawala, Dehardun- 248 161, Uttarakhand, India. Tel: 91-135-2685753, 2686286, Fax:2686286. E-mail: sbspgi@gmail.com Website: www.sbspgi.edu.in
Approved by AICTE., New Delhi, PCI, New Delhi and affiliated to Uttarakhand Technical University, Dehradun

Date:..

CERTIFICATE
This is to certify that the work incorporated in the dissertation entitled, Isolation of curcuminoids from turmeric of different regions submitted by Miss.Prabhjot Kaur in partial fulfilment of the requirements and regulations for the award of the degree of the Bachelors in Pharmacy of Uttarakhand Technical University, (Dehradun) Uttarakhand, India is a bonafide research work carried out by him in Department of Pharmaceutical Sciences, S.B.S.(PG) Institute of Biomedical Sciences & Research, Balawala, Dehradun under my guidance during academic year 2011 - 2012. No part of this project is submitted for any other degree.

Forwarded By: Dr. Veerma Ram (HOD)

Supervisor: Dr. S.K. Dubey Associate. Proffessor Department of Pharmaceutical Sciences

Internal Examiner Examiner

External

Department of Pharmaceutical Sciences S.B.S. (PG) Institute of Biomedical Sciences and Research Balawala, Dehradun ( 2012-2013 )

DECLARATION
I hereby declare that the work embodied in this Project is a bonafide work carried out by me under the supervision and guidance of Dr.S.K.Dubey, Associate Prof. Department of Pharmaceutical Sciences, Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences and Research, Balawala, Dehradun, Uttarakahnd, India. This work has not been submitted in part or full in this or any other University / College / Institute for the award of any Diploma or Degree. In this work, I have not incorporated any copyrighted material without prior permission from the copyright holder and acknowledgement. I have checked all the references and citations for their correctness.

Date:.. Place: Balawala, Dehradun PRABHJOT KAUR ( Roll No. 09270300043 ) Batch: 2009-2013 Academic Session: 2012-13 Class: B.PHARM.(8th SEM.)

ACKNOWLEDGEMENT
With extreme gratitude and indebtedness, I wish to express my acknowledgement towards my project guide Dr.S.K.Dubey, Assoc.Prof.,Department of Pharmaceutical Sciences, Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences and Research, Balawala, Dehradun for his unparallel and excellent guidance, constant inspiration and continuous sencouragement throughout the dissertation work. I am highly indebted to our Founder Director Late S. Gurucharan Singh Ji, Chairman Shri S.P. Singh, Managing Secretary Dr. Gaurav Deep Singh, and Additional Director(Adm), Brig (Retd) P.P.S Pahwa, SBSPGI Balawala, Dehradun for giving me this opportunity to be a part of this esteemed institute. I am immensely thankful to Prof. (Dr.) Veerma Ram, Head, Department of Pharmaceutical Sciences, Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences and Research, Balawala, Dehradun for his constructive comments and suggestions from time to time. I express my sincere thanks to all the faculty members for their help and cooperation during the project work. I also express my sincere thanks to the librarian and other library staff. With due regards I would like to thank all the gynaecologists and patients for their cooperation as without them this project would not be completed. I wish to express my sincere thanks to all my friends for their genuine help and kind support during this work. I would also like to thank Mrs. Nalini Mehrishi, Warden, Mata Gujri Girls Hostel for her all time support and encouragement. I would like to pay my deep regards to my parents and my all family members for their unconditional love, support and blessings due to which this work reached to the completion. I also thank the various Store incharges of the sub stores of the department for extending their full cooperation. Once again I would like to thank all those who were directly or indirectly involved in the completion of this project. Date : _______________ Place :Balawala, Dehradun KAUR PRABHJOT

CONTENTS
S.NO. 1. 2. 3 4 5. CHAPTERS Introduction Sources of Resins Literature review Curcumin Isolation of curcuminoids PAGE NO. 1-2 3-4 5-12 13-24 25-30

6. 7. 8.

Material & Methods Result Reference

31-32 33-34 35-36