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com Pin 560 032 ----------------------------------------------------------------------------------------Contact details: Res: +91 (80) 23657282 Mob: +91 98443 07260
Objective:
To contribute to the field of Biology by sharing my knowledge and combining my Industry Experience to bridge the gap between Theory and Practice.
Experience Summary:
Freelance Experience: 3 years in article writing and online teaching
Article Writing Submitted 10+ online articles at o ezinearticles.com:http://ezinearticles.com/?expert=Annapurna_Edara o articlesbase.com: http://www.articlesbase.com/authors/annapurna/237928 o own blogs: http://purnasrinivas.blogspot.com o own site: http://purnasrinivas.weebly.com Online teaching Conducted many classes, online tests and submitted tutorials at o WizIQ.com http://www.wiziq.com/annapurna o Blueteach.com: http://www.blueteach.com/u/annaP1 o You tube - http://www.youtube.com/purnasrinivas
Industry Experience: 4 Years and 8 months (2 Years 4 months Database Curation; 2 Years 4 months Teaching)
Software Skills:
Operating Systems Languages RDBMS Teaching aids Windows XP, Linux C, PHP, HTML, XML MySql MS-Word, PowerPoint and online white board
Positive Strengths:
Good knowledge of the Curation Aspects in Bio-informatics Good Presentation Skills Dedication and sincerity towards the work
Online Activities:
Online Publications:
ANNA PURNA E.
purnasrinivas@gmail.com
RNA Interference - A Regulatory Mechanism in a Living Cell Pathway Curation: An Upcoming Area in Bioinformatics Packaging of DNA into Microscopic Nucleus Osmosis in Living Systems Nucleic Acid: The Molecular Basis of Inheritance Brain Damage Affects Mental Processes And Behavior Biological Water Purification Natural Indian Food Preservatives
Online Class Topics: Crossing Over and Random Assortment Cell Division Meiosis Cell Division Mitosis Water Transport in Plants Regulation of Gene Expression in Eukaryotes Packaging of DNA into Microscopic Nucleus Molecular Basis of Inheritance
Academic Qualification:
Degree P.G.Diploma in BioInformatics M.Sc. Biochemistry PG Certificate Course in Nutrition University/ Institute Small Industries Service Institute (SISI), Chennai, Tamil Nadu Nagarjuna University, Guntur, Andhra Pradesh National Institute of Nutrition, Hyderabad, Andhra Pradesh Period Jul 2002 Jan 2003 Aug 1998 Apr 2000 Jan 2001 Mar 2001
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ANNA PURNA E.
purnasrinivas@gmail.com
Bio-informatics Software
Blast, Fasta, PHYLIP, EMBOSS, SPDBV, RASMOL, ClustalW, Protein Structure Prediction and Analysis Programs, BioEdit, HEX, Chime.
Laboratory Experience:
Well acquainted with techniques like HPLC, SDS-Page Electrophoresis and SRID.
Industry Projects:
1 Title Annotating Scientific Research Papers related to 1)Immune responses in human beings 2)Effect of Leishmania major in human beings 3)Role of integrins in human beings Transpath Transtool Windows XP 21 Months (From Nov 2007 To July 2009) 12 Annotation and curation of proteins involved in human inflammatory responses. Curating the scientific literature related to immune response and integrins which ultimately builds up the signaling pathway in human beings. Plasma Proteome Database Creation HUPO XML, JAVA Linux, Windows 7 months ~30 Annotation and Review of plasma proteins The Plasma Proteome project was initiated by HUPO, where plasma proteins were characterized and multiple peptides were identified. Plasma Proteome Database Creation involved annotation of the above plasma proteins. Plasma Proteome Database is a web-based resource that contains a functional annotation of all these plasma proteins. The database can be accessed at
Title Client Software Operating system Duration Team size Role Description
www.plasmaproteomedatabase.org
3 Title Client Software Operating System Duration Team size Human Protein Reference Database (HPRD) NCBI XML, JAVA, ZOPE Linux, Windows 7 months ~30
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ANNA PURNA E.
purnasrinivas@gmail.com
Role Description
Data-mining, Annotation and Curation of various proteins in HPRD by intensive literature survey HPRD is an object database that integrates information relevant to the function of human proteins in health and diseases. Data pertaining to protein-protein Interactions, Post-translational modifications, Enzyme-substrate relationships were extracted from the literature. (www.hprd.org) Intra-cellular Signaling Pathways Linux, Windows 3 months ~10 Literature Survey, Annotation, Feeding information in Biopax format, drawing Genmap and Validation using PSI-MI format. This project studies the binding of Signaling Molecules (Enzymes and Hormones) with the receptors or substrates, with the aim of finding the genetic implication of the reaction. My role was the annotation of intermediate molecules and creation of the signaling pathway. Information was fed in Biopax format and genmap was generated. The entire pathway was validated using the PSI-MI format. Bioce Amity Resources (P) Ltd., Bio-Informatics Institute of India, Chennai HTML, PHP, C, Java and MySql Linux, Windows 6 months 4 Guiding the software personnel to understand the Biological applications of the software and analyzing the reports and results with other software. This project deals with the Molecular Dynamics part of Drug Design. The aim of the project was to find a peptide with the desired amino acids having the least energy state for maximum stability. Bioce software, a freeware which provides a platform for simulation of molecules and joining amino acids to form peptides, was used. It allows calculation of energy states for various rotations. Protein Ligand Database Amity Resources (P) Ltd., Bio-Informatics Institute of India, Chennai PHP, MySql Linux, Windows 6 months 2 Collecting data related to autoimmune diseases, isolating the target protein and analyzing the structure of protein using various Protein Analysis and Structure Prediction tools. This database contains the information of the target Proteins in Autoimmune diseases and their respective Ligands. Estimation of Vit A and Vit E levels through HPLC techniques during the Certificate Course at National Institute of Nutrition. Myasthenia gravis, an autoimmune disease-this was the bio project under Bio-informatics course in which my task was to
Title Client Software Operating System Duration Team Size Role Description
Title Client Software Operating System Duration Team Size Role Description
Other Projects:
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ANNA PURNA E.
purnasrinivas@gmail.com
determine the active site and predict the structure of acetyl choline receptor which gets mainly affected in myasthenia gravis and also to study the reasons for molecular mimicry Transcription- As a computer project during my Bio-informatics course my task was to build an interface using PHP. The program for transcription was written using C language Publications worked on 1) Plasma Proteome Database as a Community Resource for Proteomics (published in Proteomics 2005, 5, 00000000) 2) Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans (expected to be published in genome research in Jan 2006) 3) A paper on genetically modified foods in the quarterly magazine of National Institute of Nutrition, Hyderabad. (Published) A Seminar-cum-Workshop on Bio-informatics was organized by Central Sericulture Training and Research Institute at Mysore
Seminars Attended
Personal Profile
Date of Birth Gender Marital Status Husbands Name Nationality 16 Sep 1976 Female Married Sarma E.S. Indian
ANNA PURNA E.
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