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A L L E R D R Y L

d i p h e n h y d r a m A M I d i p h e n h y d r A M I N E

Theraputic: allergy, cold, and cough remedies, antihistamines, antitussives

Antagonizes the effects of histamine at H1-receptor sites; does not bind to or inactive histamin. Significant CNS depressant and anti cholinergic properties. Theraputic Effects: Decreased syptoms of histamine excess (sneezing, rhinorrhea, nasal and occular pruritis, ocular tearing and redness, uticaria). Relief of acute dystonic reactions. Prevention of motion sickness. Suppresion of cough.

Relief of allergic symptoms caused by histamine release including: Anaphylaxis, Seasonal and perenial allergic rhinitis, Allergic dermatoses. Parkinson's disease and dystonic reactions from medicactions. Mild nightime sedation. Prevention of motion sickness.

Hypersensitivity; Acute attacks of asthma; Lactation; Known alcohol intolerance (some liquid products). Use Cautiously in: Severe liver disease; Angleclosure glaucoma; Seizure disorders; Prostatic hyperplasia; Peptic ulcer.

CNS: drowsiness, dizziness, headache. EENT: blurred vision, tinnutus. CV: hypotension, palpitations. GI: anorexia, dry mouth, constipation, nausea. GU: dysuria, frequency, urinary retention. Derm: photosensitivity. Resp: chest tightness, thickened bronchial secretions, wheezing. Local: pain at IM site.

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Determine why the medication was ordered and asses symptoms that apply to the individual patient. Assess for uticaria and for patency of airway. Assess degree of nasal stuffness, rhinorrhea, and sneezing. Assess movement disorder before and after administration. Assess sleep paterns. Assess nausea, vomitting, bowel sounds, and abdominal pain. Assess frequency and nature of cough, lung sounds, and amount and type of sputum produced. Unless contraindicated, maintain fluid intake of 1500-2000 ml daily to decrease viscousity of bronchial secretions. Assess degree of itching, skin rash, and inflamation. Diphenhydramine may decrease skin response to allergy tests. Discontinue days before skin testing. Caution patient to avoid use of alcohol and other CNS depressants concurrently with this medication. Teach sleep hygine techniques (dark room, quiet, bedtime ritual, limit daytime napping, avoidance of nicotine and caffine) to patients taking diphen hydramine to aid sleep. Advise patient to use sunscreen and protective clothing to prevent photosensitivity reactions. Do not confuse Benadryl (diphenhydramine) with Benylin (dextromethorpan), desipramine (Norpramin) or with dimenhydrinate (Dramamine).

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