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Senior Researcher, BioNanotechnology Research Group Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea TEL)

42-879-8449, FAX) 42-879-8594, Mobile) 011-651-0626 E-mail; yongtaik@kribb.re.kr or kaistchem@hotmail.com Education 1998.3 - 2002. 2. Ph.D. in KAIST Department of Chemical and Biomolecular Engineering Ph.D. Thesis: "Polymer Nanocomposites with Controlled Nanostructure for Photonic and Electro-Responsive Materials" (Advisor : O Ok Park, Co-advisor : Hee-Tae Jung ) 1996.3 - 1998. 2. M.S. in KAIST Department of Chemical Engineering 1992.3 - 1996. 2. B.S. in Sogang University Department of Chemical Engineering, Research Experience 2004.7 - present Korea Research Institute of Bioscience and Biotechnology Senior Researcher, BioNanotechnology Research Group 2003.3 - 2004. 6. Electronics and Telecommunications Research Institute (ETRI) Senior Researcher, BioMEMS Group 2002.3 - 2003. 2. Harvard Medical School, Post-Doctoral Research Fellow, (Division of Hematology/Oncology). (Advisor: Dr. John. V. Frangioni) 2002.9 2003. 2. Massachusetts Institute of Technology (MIT) Visiting Scientist, Department of Chemistry (Advisor: Dr. Moungi G. Bawendi) 1998.3 2002. 2. Korea Advanced Institute of Science and Technology (KAIST) Research Fellow and Teaching Assistant Fields of Research Interest Synthesis and Application of Engineered Nanomaterials for MRI and Biophotonics NanoBiotechnology for Biomedical Applications. Biomedical Optical Molecular Imaging (Near-Infrared Responsive Nanoparticles) BioMEMS for Disease Detection and Analysis. Organic and Inorganic Hybrid Nanostructured Materials.

Yong Taik Lim, Ph.D.

Awards

-KOSEF Postdoctoral Fellowship, 2002, Korea Science and Engineering Foundation. -Graduation with Highest CGPA, Summa Cum Laude, 1996, Sogang University.

Publications

Lim, Y.T., M.Y. Cho, J. M. Lee, S. J. Chung and Chung, B.H., " Simultaneous Intracellular delivery of Antibodies and Nanoparticles with an Engineered Protein G System, Biomaterials, 30(6) (February 2009), 1197-1204. Lim, Y.T., J.K. Kim, Y.-W. Noh, M.Y. Cho and Chung, B.H., " Multifunctional Silica Nanocapsule with a Single Surface Hole, Small (2009, in press) W.-S. Cho, M. Cho, J. Jeong, M. Choi, H.-Y. Cho, B.S.Han, Sheen Hee Kim, H. O. Kim, Lim, Y.T., B.H. Cung, J. Jeong, " Acute toxicity and pharmacokinetics of 13nm-sized PEG-coated gold nanoparticles, Toxicology and Applied Pharmacology (2009, in press) Lim, Y.T., M.Y. Cho, B. S. Choi, J. M. Lee and Chung, B.H., " Paramagnetic gold nanostructures for dual modal Bioimaging and phototherapy of cancer cells, Chem. Comm. 2008 (40), 4930-4932 (Highlighted in Chemical Technology, Nanoparticles hunt down cancer cells, 3 September, 2008) Lim, Y.T., Y.-W. Noh, J. H Han, Q.-Y. Cai, K.-H. Yoon, Chung, B.H., "Biocompatible Polymer Nanoparticles-Based Bimodal Imaging Contrast Agents for the Labeling and Tracking of Dendritic Cells, Small, 4(10), 1640-1645 (2008). Lim, Y.T., Cho, M.Y., B.S. Choi, Y.-W. Noh, Chung, B.H., "Diagnosis and therapy of macrophage cells using dextran-coated near-infrared responsive hollow-type gold nanoparticles ", Nanotechnology, 19(37), 375105 (2008) Y.-W. Noh, Lim, Y.T.*, Chung, B.H*., "Non-invasive Imaging of Dendritic Cell Migration into Lymph Nodes using Near-infrared Fluorescent Semiconductor Nanocrystals ", FASEB Journal, 22(11), 3908-3918 (2008) (*: Corresponding Author) A. Gokarna, S.-K. Lee, J.-S. Hwang, Y. H. Cho, Y.T. Lim, B. H. Chung, S. H. M. Lee, " Fabrication of CdSe/ZnS Quantum-Dot-Conjugated Protein Microarray and Nanoarrays, Journal of the Korean Physical Society, 53(5), November (2008) Park, H.K., Lim, Y.T., Kim, J.K., Park, H.G., Chung, " Nanoscopic observation of gold nanoparticle-conjugated protein using near-field scanning field microscopy, Ultramicroscopy, 108, 1115-1119 (2008). A. Gokarna, L. H. Jin, J. S. Hwang, Y. H. Cho, Y.T. Lim, B. H. Chung, S. H. Youn, D. S. Choi, and J. H. Lim., " Quantum dot-based protein micro- and nanoarrays for detection of prostate cancer biomarkers, Proteomics, 8(9), 1809-1818 (2008) Park, H.Y., Oh, K.S., Koo, H.M., Cho, S.H.,Chung, S.J. Lim, Y.T., Kim, D., Yuk, S.H., "Heparinimmobilized pluronic/PVA composite microparticles for the sustained delivery of ionic drug, Journal of Microencapsulation, 25(2), 106-110 (2008) Seo, K.-D., Lee, K.-P., Gopalan, A.I., Chung, S.J., Lim, Y.T., Choi, S.-H., "Horseradish peroxidase (HRP) immobilized poly(aniline-co-m-aminophenol) film electrodes fabrication and evaluation as hydrogen peroxide sensor", Sensors, 7(5), 719-729 (2007) Lim, Y.T., Cho, M.Y., Kim, J.K., Hwangbo, S., Chung, B.H., "Plasmonic magnetic nanostructure for bimodal imaging and photonic-based therapy of cancer cells ", ChemBioChem, 8(18), 22042209 (2007) (IF = 4.1)

Y.T. Lim, J.K. Kim, Y.B. Shin, B.H. Chung "Wavelength and Intensity Multiplexing of Metal Nanoparticles for the Fabrication of Multicolor Micro- and Nano-Spheres ", Advanced Functional Materials, 16, 1015-1021 (2006) (IF = 6.770) Y.T. Lim, K.Lee, K.Lee, B.H. Chung "Immobilizaiton of histidine-tagged proteins using phospholipid encapsulated magnetic nanoparticles ", Biochemical and Biophysical Research Communications 344, 926-930 (2006) ( IF = 3.0) Y.T. Lim, S. Kim, H. Yang, K, Kim " Controlling the hydrophilicity of microchannels with bonding adhesives containing surfactants", Journal of Micromechanics and Microengineering 16, N9-N16 (2006) ( IF = 2.499) Y.T. Lim, J.K. Kim, B.H. Chung "Multicolor Nanospheres Fabricated by In Situ Transformation of Metal Nanostructure on the Surface of Polymer Spheres", Nanotechnology 17, 3699-3702 (2006) ( IF = 2.993) S. Kim, H. Yang, K, Kim, D. Y.T. Lim, H.B. Pyo "Study of SU-8 for Ni master-mold : adhesion, sidewall profile, removal", Electrophoresis, 27, 3284-3296 (2006) (IF = 3.850) S. Kim, Y.T. Lim, H. Yang, Y.B. Shin, K, Kim, D. Lee, S. H. Park, Y.T. Kim "Passive microfluidic control of two streams by capillarity and flow resistance", Analytical Chemistry, 77,6494-6499 (2005) (IF = 5.635) (October 1) Y.T. Lim*, S. Kim*, (Lim* is a first co-author in this paper) E.G. Soltesz, A.M. DeGrand, J. Lee, A. Nakayama, J.A. Parker, T. Mihaljevic, R.G. Laurence, D.M. Dor, L.H. Cohn, M. Bawendi and J.V. Frangioni, "Near-Infrared Fluorescent Type-II Quantum Dots for Sentinel Lymph Node Mapping", Nature Biotechnology, 22,93-97 (2004) (IF = 22.738) K. Kim, H. Yang, S. H. Park, D. Lee, S. Kim, Y.T. Lim, and Y. T. Kim, "Washing-Free Electrochemical DNA Detection Using Double-Stranded Probes and Competitive Hybridization Reaction", Chemical Communications, 13, 1466-1467 (2004) (IF = 4.426) (July) J.H. Park, Y.T. Lim, O O. Park, J. K. Kim, J.-W. Yu and Y.-C. Kim, "Stabilized Blue Emission from Polymer-Dielectric Nanolayer Nanocomposites", Advanced Functional Materials,14,377-382 ( 2004)(IF = 6.770) (April) J.H. Park, Y.T. Lim, O O. Park, J. K. Kim, J.-W. Yu, Y.-C. Kim, "Polymer/Gold Nanoparticle Nanocomposite Light-Emitting Diodes; Enhancement of Electroluminescence Stability and Quantum Efficiency of Blue-Light-Emitting Polymers", Chemistry of Materials,16,688-692 ( 2004) (IF = 4.818) (February) J.H. Park, Y.T. Lim, O O. Park, J.-W. Yu, J. K. Kim, Y.-C. Kim, "Enhanced quantum efficiency in blue-emitting polymer/dielectric nanolayer nanocomposite light-emitting devices", Materials Science and Engineering C-Biomimetic and Supramolecular Systems, 24,75-78 ( 2004)(IF = 1.383) (January) J.H. Park, Y.T. Lim, O O. Park, J. K. Kim, and Y.-C. Kim, " Blue Light Emitting Polymer/Dielectric Nanolayer Nanocomposites: Impediment of Excimer Formation and Enhancement of Photostability", Journal of Nonlinear Optical Physics and Materials , 13,607-611 ( 2004)(IF = 0.747) (December)

16. Y.T. Lim, S. Kim, A. Nakayama, N.E. Scott, M. Bawendi and J.V. Frangioni, "Selection of Quantum Dots Wavelengths for Biomedical Assays and Imaging", Molecular Imaging, 2(1), 50-64 (2003) Y.T. Lim, O O. Park, and H.-T. Jung, "Gold Nanolayer-encapsulated Silica Particles Synthesized by Surface Seeding and Shell Growing Method; Near-infrared Responsive Materials ", Journal of Colloid and Interface Science, 263,449-453(2003)(IF = 2.023) J.H. Park, Y.T. Lim, O O. Park and Y.-C. Kim, " Enhancement of Photostability in Blue LightEmitting Polymers Doped with Gold Nanoparticles", Macromolecular Rapid Communications, 24, 331-334 ( 2003)(IF = 3.126) S.H. Im, Y.T. Lim, D.J. Suh, and O O. Park, "Three-dimensional self-assembly of colloids at a water-air interface : A novel technique for the fabrication of photonic bandgap crystals", Advanced Materials, 14,1367-1369 (2002)(IF = 9.107) Y.T. Lim , T.-W., Lee, H.-C., Lee, and O O. Park, "Enhanced Photo-stability of Conjugated Polymer Nanocomposites doped with Functionalized Nanoparticles", Optical Materials, 21,585-589 (2002)(IF = 1.162) Y.T. Lim, T.-W., Lee, H.-C., Lee, and O O. Park, "Impediment of photooxidation in PPV nanocomposites doped with metal coated silica nanoparticles", Synthetic metals, 128(2),133-137 (2002)(IF = 1.320) Y.T. Lim, J.H. Park, and O O. Park, "Improved electrorheological effect in polyaniline nanocomposite suspensions", Journal of Colloid and Interface Science, 245,198-203 (2002)(IF = 2.023) H.-C., Lee, T.-W., Lee, Y.T. Lim, and O O. Park, "Improved Environmental Stability in poly(pphenylenevinylene)/layered silicate nanocomposite", Applied Clay Science, 21,287-293 (2002)(IF = 1.324) J.H. Park, Y.T. Lim and O O. Park, " New Approach to Enhance Yield Stress of ElectroRheological Fluids by Polyaniline-coated Layered Silicate Nanocomposites", Macromolecular Rapid Communications, 22, 616-619 (2001)(IF = 3.126) Y.T. Lim and O O. Park, "Phase morphology and rheological behavior of polymer/layered silicate nanocomposites" Rheologica Acta, 40,220-229 (2001)(IF = 1.432) Y.T. Lim and O O. Park, "Microstructure and Rheological Behavior of Block Copolymer/Clay Nanocomposites", Korean Journal of Chemical Engineering, 18, 21-25 (2001)(IF = 0.750) Y.T. Lim and O O. Park, "Rheological evidence for the microstructure of intercalated polymer/layered silicate nanocomposites" Macromolecular Rapid Communications, 21, 231-235 (2000)(IF = 3.126) D.J. Suh, Y.T. Lim and O O. Park, "The property and formation mechanism of unsaturated polyester-layered silicate nanocomposite depending on the fabrication methods", Polymer, 41, 8557-8563 (2000)(IF = 2.849) J.W. Lee, Y.T. Lim and O O. Park, " Thermal characteristics of organoclay and their effects upon the formation of polypropylene/organoclay nanocomposites", Polymer Bulletin, 45, 191-198 (2000) (IF = 0.904)

Y.T. Lim, H.M. Lee and O O. Park, " Effect of Interface on the Rheological Behaviors of PS/PP and EDPM/PP Polymer Blends", Korean Journal of Rheology, 10, 14-23 (1998)(IF = 0.727)