U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 Q: How common are migraines? A: Migrainepainandsymptomsaffect 29.5millionAmericans.Migraineis themostcommonformofdisabling headachethatsendspatientstoseetheir doctors. Q: What causes migraines? A: Theexactcauseofmigraineisnotfully understood.Mostresearchersthinkthat migraineisduetoabnormalchanges inlevelsofsubstancesthatarenaturally producedinthebrain.Whenthelevels ofthesesubstancesincrease,theycan causeinf lammation.Thisinf lammation thencausesbloodvesselsinthebrainto swellandpressonnearbynerves,caus- ingpain. Genesalsohavebeenlinkedto migraine.Peoplewhogetmigraines mayhaveabnormalgenesthatcontrol thefunctionsofcertainbraincells. Expertsdoknowthatpeoplewith migrainesreacttoavarietyoffactors andevents,calledtriggers.Thesetrig- gerscanvaryfrompersontoperson anddontalwaysleadtomigraine.A combinationoftriggersnotasingle thingoreventismorelikelytoset offanattack.Apersonsresponseto triggersalsocanvaryfrommigraineto migraine.Manywomenwithmigraine tendtohaveattackstriggeredby: lackofortoomuchsleep skippedmeals brightlights,loudnoises,orstrong odors hormonechangesduringthemen- strualcycle Migraine Q: What is migraine? A: Migraineisamedicalcondition.Most peoplewhosufferfrommigrainesget headachesthatcanbequitesevere.A migraineheadacheisusuallyanintense, throbbingpainonone,orsometimes, bothsidesofthehead.Mostpeople withmigraineheadachefeelthepainin thetemplesorbehindoneeyeorear, althoughanypartoftheheadcanbe involved.Besidespain,migrainealso cancausenauseaandvomitingandsen- sitivitytolightandsound.Somepeople alsomayseespotsorf lashinglightsor haveatemporarylossofvision. Migrainecanoccuranytimeofthe day,thoughitoftenstartsinthemorn- ing.Thepaincanlastafewhoursor uptooneortwodays.Somepeople getmigrainesonceortwiceaweek. Others,onlyonceortwiceayear.Most ofthetime,migrainesarenotathreat toyouroverallhealth.Butmigraine attackscaninterferewithyourday-to- daylife. Wedontknowwhatcausesmigraine, butsomethingsaremorecommonin peoplewhohavethem: Mostoften,migraineaffectspeople betweentheagesof15and55. Mostpeoplehaveafamilyhistoryof migraineorofdisablingheadache. Theyaremorecommoninwomen. Migraineoftenbecomeslesssevere andlessfrequentwithage. stressandanxiety,orrelaxationafter stress weatherchanges alcohol(oftenredwine) caffeine(toomuchorwithdrawal) foodsthatcontainnitrates,suchas hotdogsandlunchmeats foodsthatcontainMSG(monoso- diumglutamate),af lavorenhancer foundinfastfoods,broths,season- ings,andspices foodsthatcontaintyramine,such asagedcheeses,soyproducts,fava beans,hardsausages,smokedfish, andChiantiwine aspartame(NutraSweetand Equal) Topinpointyourmigrainetriggers, keepaheadachediary.Eachdayyou haveamigraineheadache,putthatin yourdiary.Alsowritedownthe: thetimeofdayyourheadachestart- ed whereyouwereandwhatyouwere doingwhenthemigrainestarted whatyouateordrank24hours beforetheattack eachdayyouhaveyourperiod,not justthefirstday(Thiscanallow youandyourdoctortoseeifyour headachesoccuratthesameorsim- ilartimeasyourperiod.) Talkwithyourdoctoraboutwhatsets offyourheadachestohelpfindthe righttreatmentforyou. oago 2 Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 Q: Are there different kinds of migraine? A: Yes,therearemanyformsofmigraine. Thetwoformsseenmostoftenare migrainewithauraandmigrainewith- outaura. Migrainewithaura(previouslycalled classicalmigraine).Withamigraine withaura,apersonmighthavethese sensorysymptoms(theso-called aura)10to30minutesbeforean attack: seeingf lashinglights,zigzaglines,or blindspots numbness;ortinglinginthefaceor hands disturbedsenseofsmell,taste,or touch feelingmentallyfuzzy Onlyoneinfivepeoplewhoget migraineexperienceanaura.Women havethisformofmigrainelessoften thanmen. Migrainewithoutaura(previously calledcommonmigraine).Withthis formofmigraine,apersondoesnot haveanaurabuthasalltheotherfea- turesofanattack. Q: How can I tell if I have a migraine or just a bad tension- type headache? A: Comparedwithmigraine,tension-type headacheisgenerallylesssevereand rarelydisabling.Compareyoursymp- tomswiththoseinthefollowingchart toseewhattypeofheadacheyoumight behaving. SYMPTOM TENSION MIGRAINE Intensity and quality of pain Mild-to-moderate x x Moderate-to-severe x Intense pounding or throbbing and/or debilitating x Distracting, but not debilitating x Steady ache x x Location of pain One side of head x Both sides of head x x Other symptoms Nausea, vomiting x Sensitivity to light and/or sounds rare x Aura before onset of headache x Note: Rebound headache may have features of tension and/or migraine headache Adapted from a table produced by the American Council for Headache Education oago 3 Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 Althoughfatigueandstresscanbring onbothtensionandmigrainehead- aches,migrainescanbetriggeredby certainfoods,changesinthebodys hormonelevels,andevenchangesin theweather. Therealsoaredifferencesinhowtypes ofheadachesrespondtotreatmentwith medicines.Althoughsomeover-the- counterdrugsusedtotreattension-type headachessometimeshelpmigraine headaches,thedrugsusedtotreat migraineattacksdonotworkforten- sion-typeheadachesformostpeople. Youcan'ttellthedifferencebetweena migraineandatension-typeheadache byhowoftentheyoccur.Bothcan occuratirregularintervals.Also,inrare cases,bothcanoccurdailyoralmost daily. Q: How can I tell if I have a migraine or a sinus headache? A: Manypeopleconfuseasinushead- achewithamigrainebecausepainand pressureinthesinuses,nasalconges- tion,andwateryeyesoftenoccurwith migraine.Tofindoutifyourheadache issinusormigraine,askyourselfthese questions: Inadditiontomysinussymptoms,doI have: 1. moderate-to-severeheadache 2. nausea 3. sensitivitytolight Ifyouansweryestotwoorthreeof thesequestions,thenmostlikelyyou havemigrainewithsinussymptoms.A truesinusheadacheisrareandusually occursduetosinusinfection.Inasinus oago + Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 infection,youwouldalsolikelyhavea feverandthicknasalsecretionsthatare yellow,green,orblood-tinged.Asinus headacheshouldgoawaywithtreat- mentofthesinusinfection. Q: When should I seek help for my headaches? A: Sometimes,headachecansignalamore seriousproblem.Youshouldtalkto yourdoctoraboutyourheadachesif: youhaveseveralheadachesper monthandeachlastsforseveral hoursordays yourheadachesdisruptyourhome, work,orschoollife youhavenausea,vomiting,vision, orothersensoryproblems(suchas numbnessortingling) youhavepainaroundtheeyeorear youhaveasevereheadachewitha stiffneck youhaveaheadachewithconfusion orlossofalertness youhaveaheadachewithconvul- sions youhaveaheadacheafterablowto thehead youusedtobeheadache-free,but nowhaveheadachesalot Q: What tests are used to find out if I have migraine? A: Ifyouthinkyougetmigrainehead- aches,talkwithyourdoctor.Before yourappointment,writedown: 1. howoftenyouhaveheadaches 2. wherethepainis 3. howlongtheheadacheslast 4. whentheheadacheshappen,suchas duringyourperiod 5. othersymptoms,suchasnauseaor blindspots 6. anyfamilyhistoryofmigraine 7. allthemedicinesthatyouaretak- ingforallyourmedicalproblems, eventheover-the-countermedicines (betterstill,bringthemedicinesin theircontainerstothedoctor) 8. allthemedicinesyouhavetakenin thepastthatyoucanrecalland,if possible,thedosesyoutookandany sideeffectsyouhad Yourdoctormayalsodoanexamand askmorequestionsaboutyourhealth history.Thiscouldincludepasthead injuryandsinusordentalproblems. Yourdoctormaybeabletodiagnose migrainejustfromtheinformationyou provide. Youmaygetabloodtestorothertests, suchasCTscanorMRI,ifyourdoc- torthinksthatsomethingelseiscausing yourheadaches.Workwithyourdoctor todecideonthebesttestsforyou. Q: Are migraine headaches more common in women than men? A: Yes.Aboutthreeoutoffourpeople whohavemigrainesarewomen. Migrainesaremostcommoninwomen betweentheagesof20and45.Atthis timeoflifewomenoftenhavemore job,family,andsocialduties.Women tendtoreportmorepainfulandlonger lastingheadachesandmoresymptoms, suchasnauseaandvomiting.Allthese factorsmakeithardforawomantoful- fillherrolesatworkandathomewhen migrainestrikes. oago 5 Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 Q: I get migraines right before my period. Could they be related to my menstrual cycle? A: Morethanhalfofmigrainesinwomen occurrightbefore,during,oraftera womanhasherperiod.Thisoftenis calledmenstrualmigraine.But,just asmallfractionofwomenwhohave migrainearoundtheirperiodonly havemigraineatthistime.Mosthave migraineheadachesatothertimesof themonthaswell. Howthemenstrualcycleandmigraine arelinkedisstillunclear.Weknowthat justbeforethecyclebegins,levelsofthe femalehormones,estrogenandpro- gesterone,godownsharply.Thisdrop inhormonesmaytriggeramigraine, becauseestrogencontrolschemicals inthebrainthataffectawomanspain sensation. Talkwithyourdoctorifyouthinkyou havemenstrualmigraine.Youmayfind thatmedicines,makinglifestylechang- es,andhometreatmentmethodscan preventorreducethepain. Q: Can migraine be worse during menopause? A: Ifyourmigraineheadachesareclosely linkedtoyourmenstrualcycle,meno- pausemaymakethemlesssevere.As yougetolder,thenauseaandvomiting maydecreaseaswell.Abouttwo-thirds ofwomenwithmigrainesreportthat theirsymptomsimprovewithmeno- pause. Butforsomewomen,menopause worsensmigraineortriggersthemto start.Itisnotclearwhythishappens. Menopausalhormonetherapy,which isprescribedforsomewomenduring menopause,maybelinkedtomigraines duringthistime.Ingeneral,though, theworseningofmigrainesymptoms goesawayoncemenopauseiscomplete. Q: Can using birth control pills make my migraines worse? A: Insomewomen,birthcontrolpills improvemigraine.Thepillsmayhelp reducethenumberofattacksandtheir attacksmaybecomelesssevere.But inotherwomen,thepillsmayworsen theirmigraines.Instillotherwomen, takingbirthcontrolpillshasnoeffect ontheirmigraines. Thereasonforthesedifferentresponses isnotwellunderstood.Forwomen whosemigrainesgetworsewhenthey takebirthcontrolpills,theirattacks seemtooccurduringthelastweekof thecycle.Thisisbecausethelastseven pillsinmostmonthlypillpacksdont havehormones;theyaretheretokeep youinthehabitoftakingyourbirth controldaily.Withoutthehormones, yourbodysestrogenlevelsdropsharp- ly.Thismaytriggermigraineinsome women. Talkwithyourdoctorifyouthinkbirth controlpillsaremakingyourmigraines worse.Switchingtoapillpackinwhich allthepillsfortheentiremonthcon- tainhormonesandusingthatforthree monthsinarowcanimprovehead- aches.Lifestylechanges,suchasgetting onaregularsleeppatternandeating healthyfoods,canhelptoo. Q: Can stress cause migraines? A: Yes.Stresscantriggerbothmigraine andtension-typeheadache.Events likegettingmarried,movingtoanew home,orhavingababycancause stress.Butstudiesshowthateveryday oago 6 Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 stressesnotmajorlifechangescause mostheadaches.Jugglingmanyroles, suchasbeingamotherandwife,having acareer,andfinancialpressures,canbe dailystressesforwomen. Makingtimeforyourselfandfind- inghealthywaystodealwithstressare important.Somethingsyoucandoto helppreventorreducestressinclude: eatinghealthyfoods beingactive(atleast30minutes mostdaysoftheweekisbest) doingrelaxationexercises gettingenoughsleep Trytofigureoutwhatcausesyouto feelstressed.Youmaybeabletocutout someofthesestressors.Forexample,if drivingtoworkisstressful,trytaking thebusorsubway.Youcantakethis timetoreadorlistentomusic,rather thandealwithtraffic.Forstressorsyou cantavoid,keepingorganizedand doingasmuchasyoucanaheadoftime willhelpyoutofeelincontrol. Q: How are migraines treated? A: Migrainehasnocure.Butyour migrainescanbemanagedwithyour doctorshelp.Together,youwillfind waystotreatmigrainesymptomswhen theyhappen,aswellaswaystohelp makeyourmigraineslessfrequent andsevere.Yourtreatmentplanmay includesomeorallofthesemethods. Medicine.Therearetwowaysto approachthetreatmentofmigraines withdrugs:stoppingamigrainein progress(calledabortiveoracute treatment)andprevention.Many peoplewithmigraineusebothformsof treatment. Acute treatment.Over-the-counter pain-reliefdrugssuchasaspirin,acet- aminophen,orNSAIDs(nonsteroidal anti-inf lammatorydrugs)likeibuprofen relievemildmigrainepainforsome people.Ifthesedrugsdontworkfor you,yourdoctormightwantyouto tryaprescriptiondrug.Twoclassesof drugsthatdoctorsoftentryfirstare: Triptans,whichworkbybalancing thechemicalsinthebrain.Examples includesumatriptan(Imitrex), rizatriptan(Maxalt),zolmitriptan (Zomig),almotriptan(Axert), eletriptan(Relpax),naratrip- tan(Amerge),andfrovatriptan (Frova).Triptanscancomeas tabletsthatyouswallow,tablets thatdissolveonyourtongue,nasal sprays,andasashot.Theyshould notbeusedifyouhaveheartdisease orhighbloodpressure. Ergotderivatives(ergotaminetar- trateanddihydoergotamine),which workinthesamewayastriptans. Theyshouldnotbeusedifyouhave heartdiseaseorhighbloodpressure. Mostacutedrugsformigrainework bestwhentakenrightaway,when symptomsfirstbegin.Alwayscarry yourmigrainemedicinewithyou incaseofanattack.Forpeoplewith extrememigrainepain,apowerful rescuedrugmightbeprescribed, too.Becausenoteveryonerespondsthe samewaytomigrainedrugs,youwill needtoworkwithyourdoctortofind thetreatmentthatworksbestforyou. Prevention.Somemedicinesused dailycanhelppreventattacks.Manyof thesedrugsweredesignedtotreatother healthconditions,suchasepilepsyand depression.Someexamplesare: oago Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 antidepressants,suchasamitriptyline (Elavil)orvenlafaxine(Effexor) anticonvulsants,suchasdivalproex sodium(Depakote)ortopiramate (Topamax) beta-blockers,suchaspropranolol (Inderal)ortimolol(Blocadren) calciumchannelblockers,suchas verapamil Thesedrugsmaynotpreventall migraines,buttheycanhelpalot. Hormonetherapymayhelpprevent attacksinwomenwhosemigraines seemtobelinkedtotheirmenstrual cycle.Askyourdoctoraboutpreven- tiondrugsif: yourmigrainesdonotrespondto drugsforsymptomrelief yourmigrainesaredisablingorcause youtomisswork,familyactivities, orsocialevents youareusingpain-reliefdrugsmore thantwotimesaweek Lifestyle changes.Practicingthese habitscanreducethenumberof migraineattacks: Avoidorlimittriggers. Getupandgotobedthesametime everyday. Eathealthyfoodsanddonotskip meals. Engageinregularphysicalactivity. Limitalcoholandcaffeineintake. Learnwaystoreduceandcopewith stress. Alternative methods.Biofeedback hasbeenshowntohelpsomepeople withmigraine.Itinvolveslearninghow tomonitorandcontrolyourbodys responsestostress,suchaslowering heartrateandeasingmuscletension. Othermethods,suchasacupunc- tureandrelaxation,mayhelprelieve stress.Counselingalsocanhelpifyou thinkyourmigrainesmayberelatedto depressionoranxiety.Talkwithyour doctoraboutthesetreatmentmethods. Q: What are rebound migraines? A: Womenwhouseacutepain-relief medicinemorethantwoorthreetimes aweekormorethan10daysoutof themonthcansetoffacyclecalled rebound.Aseachdoseofmedicine wearsoff,thepaincomesback,lead- ingthepatienttotakeevenmore.This overusecausesyourmedicinetostop helpingyourpainandactuallystart causingheadaches.Reboundheadaches canoccurwithbothover-the-counter andprescriptionpain-reliefmedicines. Theycanalsooccurwhetheryoutake themforheadacheorforanothertype ofpain.Talktoyourdoctorifyoure caughtinareboundcycle. Q: Im pregnant. Can my migraines still be treated? A: Somemigrainemedicinesshould notbeusedwhenyouarepregnant becausetheycancausebirthdefects andotherproblems.Thisincludes over-the-countermedicines,suchas aspirinandibuprofen.Talkwithyour doctorifmigraineisaproblemwhile youarepregnantorifyouareplan- ningtobecomepregnant.Yourdoctor mightsuggestamedicinethatwillhelp youandthatissafeduringpregnancy. Hometreatmentmethods,suchas doingrelaxationexercisesandusing coldpacks,alsomighthelpeaseyour pain.Thegoodnewsisthatformost oago 8 Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 womenmigrainesimproveorstop fromaboutthethirdmonthofthe pregnancy. Q: I am breastfeeding. Will taking medicine for migraine hurt my baby? A: Askyourdoctoraboutwhatmigraine medicinesaresafetotakewhilebreast- feeding.Somemedicinescanbepassed throughbreastmilkandmightbe harmfultoyourbaby. Q: What are some ways I can pre- vent migraine? A: Thebestwaytopreventmigraineis tofindoutwhattriggersyourattacks andavoidorlimitthesetriggers.Since migraineheadachesaremorecommon duringtimesofstress,findinghealthy waystocutdownonandcopewith stressmighthelp.Talkwithyourdoctor aboutstartingafitnessprogramortak- ingaclasstolearnrelaxationskills. Talkwithyourdoctorifyouneedto takeyourpain-reliefmedicinemore thantwiceaweek.Doingsocanlead toreboundheadaches.Ifyourdoctor hasprescribedmedicineforyoutohelp preventmigraine,takethemexactly asprescribed.Askwhatyoushoulddo ifyoumissadoseandhowlongyou shouldtakethemedicine.Talkwith yourdoctoriftheamountofmedicine youareprescribedisnothelpingyour headaches. Q: What should I do when a migraine begins? A: Workwithyourdoctortocome upwithaplanformanagingyour migraines.Keepingalistofhometreat- mentmethodsthathaveworkedforyou inthepastalsocanhelp.Whensymp- tomsbegin: Ifyoutakemigrainemedicine,take itrightaway. Drinkf luids,ifyoudon'thavenau- seaduringyourmigraine. Liedownandrestinadark,quiet room,ifthatispractical. Somepeoplefindthefollowinguseful: acoldclothonyourhead rubbingorapplyingpressuretothe spotwhereyoufeelpain massageorotherrelaxation exercisesn oago Fre que ntl y As ke d que s ti ons U.S. Department of Health and Human Services, Office on Womens Health womenshealth.gov 1-800-994-9662 TDD: 1-888-220-5446 AllmaterialcontainedintheFAQsisfreeofcopyrightrestrictions,andmaybecopied, reproduced,orduplicatedwithoutpermissionoftheOfficeonWomen'sHealthinthe DepartmentofHealthandHumanServices.Citationofthesourceisappreciated. ThisFAQwasreviewedby: PeterJ.Goadsby,M.D.,Ph.D. DepartmentofNeurology UniversityofCalifornia,SanFrancisco SusanHutchinson,M.D. Director,OrangeCountyMigraine&HeadacheCenter B.LeePeterlin,D.O. Director,HeadacheClinic DrexelUniversityCollegeofMedicine ContentlastupdatedMay2008 For More Information Formoreinformationonmigraine,pleasecallwomenshealth.govat1-800-994-9662or contactthefollowingorganizations: National Institute of Neurological Disorders and Stroke (NINDS), NIH, HHS PhoneNumber:(800)352-9424 InternetAddress: http://www.ninds.nih.gov American Council for Headache Education (ACHE) Phone:(856)423-0258 InternetAddress:http://www.achenet.org Migraine Awareness Group: A National Understanding For Migraineurs (MAGNUM) PhoneNumber:(703)349-1929 InternetAddress:http://www.migraines. org National Headache Foundation PhoneNumber:(888)643-5552 InternetAddress: http://www.headaches.org National Menstrual Migraine Coalition InternetAddress: http://www.headachesinwomen.org