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Enthesis
Enthesis
Enthesis (plural: entheses) is the point at which a tendon or ligament[2] or muscle[3] inserts into bone, where the collagen fibers are mineralized and integrated into bone tissue. The collagen to bone interface is via Sharpey's fibers.
Classification
There are two types: Fibrous entheses Fibrocartilaginous entheses In a fibrous enthesis, the collagenous tendon or ligament directly attaches to the bone, whilst the fibrocartilaginous enthesis displays 4 zones during the transition from tendon/ligament to bone: i) tendinous area displaying longitudinally oriented fibroblasts and a parallel arrangement of collagen fibres ii) a fibrocartilaginous region of variable thickness where the structure of the cells changes to chondrocytes iii) an abrupt transition from cartilaginous to calcified fibrocartilage - the so-called 'tidemark' or 'blue line' iv) bone
Pathology
A disease of the entheses is known as an "enthesopathy" or "enthesitis" and is characteristic of spondyloarthropathy but is present in other pathologies as well. The enthesis is the primary site of ankylosing spondylitis.
References
[1] http:/ / www. unifr. ch/ ifaa/ Public/ EntryPage/ ViewTH/ THh303. html
External links
Image of enthesis (http://images.medscape.com/pi/editorial/cmecircle/2004/2890/images/slide13.gif) at Medscape Enthesopathy and Soft Tissue Shadows (http://www.chiroweb.com/archives/18/19/23.html) at chiroweb.com Resnick D, Niwayama G (1983). "Entheses and enthesopathy. Anatomical, pathological, and radiological correlation" (http://radiology.rsnajnls.org/cgi/content/abstract/146/1/1). Radiology 146 (1): 19. PMID 6849029 (http://www.ncbi.nlm.nih.gov/pubmed/6849029).
License
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