Pharmacy

Sr. No. 1. 2. 3. 4. 5. Pharmaceutics Pharmaceutical Chemistry Pharmacology Pharmacognosy Practice of Pharmacy Total Core Areas Percentage 20% 20% 20% 20% 20% 100%

Pharmacy (Detailed) Sr. No. PHAR AC!"T#CS$ 1. Pharmace%tical Princi&les and Dr%g Dosage 'orms(((((()% 1.1 Physicochemical *eha+iors$ 1.1.1 Homogeno%s Systems$ Sol%tions$ 1. Solvents, Solutes, Electrolytes, Colligati+e &ro&erties$ "o#ering of va$or $ressure, Elevation of %oiling $oint, &e$ression of free'ing $oint, (smosis an) (smotic $ressure. *%,,ers and -%,,er ca&acity$ *hat are the %uffers, +uffer action, an) +uffer ca$acity, 1.1.. Heterogeneo%s (Dis&erse) Systems$ *asics a-o%t S%s&ensions and !m%lsions Dis&ersion sta-ility$ -)eal )is$ersion, Particle si'e, &is$erse) $hase concentrations, Particle!$article interactions, &ensity. !m%lsion Sta-ility$ Creaming, Coalescence, electrostatic re$ulsion, Phase inversion, Crac.ing. 1.. Chemical /inetics and Dr%g Sta-ility$ #ntrod%ction to sta-ility o, acti+e ingredients$ /eaction rates an) or)ers of reaction. 'actors a,,ecting the reaction rates$ 0em$erature, Presence of Solvent, Change in $1, Presence of a))itives. odes o, &harmace%tical Degradation$ 1y)rolysis, (2i)ation, Photolysis. on!electrolytes .0 % Core Areas Percentag e

.. Dr%g Dosage 'orms ((((((((((((((((((((((((((((((((((()% *asics o, Dosage ,orms$ Ta-lets$ &efinition, 0y$es, 3)vantages an) )isa)vantages, 4etho)s of 4anufacturing, E2ce$ients, 0a%let )efects, Coating effects. Ca&s%les$ &efinition, 0y$es, 4etho)s of 4anufacturing, E2ce$ients. 0ral dr%g sol%tions$ Syru$s an) their a))itives, eli2irs an) their a))itives. S%s&ensions$ 0y$es, Pur$ose of sus$ensions, Sus$en)ing agents. !m%lsions$ 0y$es, Pur$ose of emulsion, Phases of emulsions, Emulsifying agents, Creams an) (intments5 -ntro)uction, 0y$es of creams an) ointments, 0y$es of their %ases, metho)s for $re$aration. S%&&ositories$ -ntro)uction, 0y$es, Su$$ository %ases, metho)s for $re$aration. Po1ders$ &efinition, 3)vantages an) &isa)vantages, 4icromeretics, 0rituration, Pulveri'ation, "evigation, S$atulation, Sim$le an) geometric mi2ing, 1ygrosco$ic, &eli6uescent su%stances, Eutectic mi2tures. Aerosol Prod%cts$ -ntro)uction, 3)vantages an) )isa)vantages, 3erosol a))itives. Sterile Prod%cts$ Sterility, -ntro)uction, a)vantages an) )isa)vantages of a))itives of -n7ecta%le. 2. *io&harmace%tics and Dr%g Deli+ery Systems ((((((((((3 % De,initions$ +io$harmaceutics, &rug Pro)uct, Pharmaco.inetics, Pharmaco)ynamics, +ioavaila%ility, +ioe6uivalence,

3%sor$tion, &istri%ution, Elimination. *io&harmace%tical Princi&les$ &rug &issolution, &rug Solu%ility, Particle si'e an) surface area, Partition coefficient an) e2tent of ioni'ation, Salt formation, Polymor$hism, Chirality, 1y)rates, Com$le2 formation. *asic Pharmaco4inetics$ 8ero or)er an) first or)er reactions, 4o)els an) com$artments, &rug &istri%ution an) elimination. *ioa+aila-ility and *ioe5%i+alence$ /elative an) 3%solute %ioavaila%ility, 39C, Cma2, 0ma2, 1alf!life, Sustaine) /elease:Controlle) /elease &osage forms, -ntro)uction, 4icroenca$sulation, 4icros$heres:4icroca$sules, &ose )um$ing. PHAR AC!"T#CA6 CH! #STR7$ 1. #nstr%mentation((((((((((((((((((((((((((((((((((((((() % +asic Princi$le, instrumentation an) Pharmaceutical a$$lications of follo#ing techni6ues5 1P"C, 9;! s$ectro$hotometery, -/ .. Chemistry o, *iomolec%les(((((((((((((((((((((((((((((8% -ntro)uction, +iological an) $harmaceutical im$ortance of Car%ohy)rates, Proteins, "i$i)s, ;itamins, En'ymes an) 1ormones 2. Princi&les o, edicinal Chemistry ((((((((((((((((((((((8% 3.1 Structure 3ctivity /elationshi$5 3.1.1 Structurally non!s$ecific )rugs, 3.1.2 Structurally s$ecific )rugs /ece$tor!site theory, /ece$tor!site +in)ing, Stereochemistry <o$tical isomers, geometric isomers an) conformational isomers= 2. PHAR AC06097$ 1. 9eneral Pharmacology((((((((((((((((((((((((((((((( 8% -ntro)uction,Pharmaco.inetics,Pharmaco)ynamics, &ose, Efficacy, Safety, Potency, &osage, &rug!&ose /es$onse curve, 0hera$eutic in)e2, /ece$tors, 3gonists an) antagonists, Pharmacological .0 %

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antagonism <Com$etitive an) on!com$etitive=, Partial antagonist, Physiological antagonism, eutrali'ing antagonism. .. echanism o, Dr%g Actions (((((((((((((((((((((((((((8 % Cell surface rece$tors, Signal trans)uction %y cell! surface rece$tors, Signaling me)iate) %y intracellular rece$tors, 0arget cell )esensiti'ation an) hy$ersensiti'ation, Pharmacological effects not me)iate) %y rece$tors <for e2am$le anesthetics an) cathartics=. 2. Pharmacology o, commonly %sed dr%g classes(((((((() % Classification, mechanism of action, in)ications an) a)verse effects of follo#ing commonly use) )rug classes5 analgesics:anti$yretics, anti!infective, antihy$ertensive, &iuretics, 3nti!$arasitic, 3nti! malarial, )rug sue) in gastrointestinal )isor)ers. :. PHAR AC09N0S7$ 1. 9eneral introd%ction ((((((((((((((((((((((((((((((((((8 % Classi,ication o, Cr%de Dr%gs 1ith S&ecial !m&hasis to Chemical and Thera&e%tical System o, Classi,ication. Terminologies %sed in Pharmacognosy; Pharmacognosy, cru)e )rugs, Pre$aration of Cru)e &rugs for Commercial 4ar.et, 4etho)s of Cultivation, &rying, Storage. Preservation, Pac.ing, &eterioration an) 3)ulteration of Cru)e &rugs. Evaluation of Cru)e &rugs <(rganole$tic, 4icrosco$ic, Physical, Chemical an) +iological=. Allergens and allergenic &re&aration(((((((((((((((((((((8 % -ntro)uction, case history, s.in test, treatment off allergy, inhalant, ingestant, in7ectant, contactant, infectant an) infestant allergens. 4echanism of allergy. 2. Se&aration and isolation o, &lant constit%ents((((((((((() % 3n intro)uction to chromatogra$hy an) chromatogra$hic techni6ues e.g. 3)sor$tion .0 %

Chromatogra$hy an) Partition Chromatogra$hy. PHAR AC7 PRACT#C!$ 1. Comm%nity=Retail Pharmacy ((((((((((((((((((((((((((:% +asic intro)uction a%out5 Prescri$tion <$arts, han)ling an) filling of $rescri$tions=, 4e)ication or)er, &ifference %et#een Prescri$tion an) 4e)ication or)er, &ose calculations, Com$oun)ing, E2tem$oraneous $re$arations, Pharmaceutical Care, &is$ensing, E$i)emiology, &rug a%use > 4isuse, Patient 4e)ication /ecor). .. edication errors((((((((((((((((((((((((((((((((((((((:% &efinition, 0y$es of errors5 *rong )rug error, E2tra )ose error, (mission error, #rong strength error, *rong route error, *rong time error, *rong )osage form errors. <. 2. Clinical Pharmacy ((((((((((((((((((((((((((((((((((((:% Clinical Pharmaco.inetics, 0hera$eutic &rug 4onitoring <0&4=, Clinical trials, -m$ortance of Clinical Pharmacy, Pharmaco!economics, Pharmaco! vigilance, Patient 3ssessment, Patient Counseling, Patient Com$liance:non!com$liance, /ational use of )rugs, &rug 9tili'ation Evaluation, &rug 9tili'ation /evie#. :. Ad+erse Dr%g Reactions(((((((((((((((((((((((((((((((:% &efinition an) )ifference %et#een 3)verse )rug reactions an) si)e effects, 0y$es of 3)verse )rug reactions <0y$e!3 an) ty$e!+=. <. Dr%g interactions((((((((((((((((((((((((((((((((((((:% 4echanism, Physiological factors affecting interaction, 0y$es an) level of )rug interactions. Total 100% .0 %