Professional Documents
Culture Documents
ACADEMIC REGULATIONS
Admission of candidates to B.Pharm first year shall be made as per the rules / directions of the
central admission authority / State Government.
3. Candidates for the Bachelor of Pharmacy course shall be instructed and examined as per the Teaching
and Examination Scheme and Course Content of respective year. The medium of instruction and
examination shall be English.
(b) A candidate who has been admitted to B.Pharm first year and has attended a regular course of
study in an affiliated college shall be eligible to appear at B.Pharm first year examination of the
University.
(c) A candidate who has been promoted to B.Pharm Second year as per the provisions for conditions
of passing or has been admitted directly to B.Pharm second year through lateral entry and has
attended as regular course of study in an affiliated college shall be eligible to appear at B.Pharm
second year examination of the University.
(d) A candidate who has been promoted to B.Pharm third year as per the provisions for conditions of
passing and has attended a regular course of study in an affiliated college shall be eligible to
appear at B.Pharm third year examination of the University.
(e) A candidate who has been promoted to B.Pharm final year as per the provisions for conditions of
passing and has attended a regular course of study in an affiliated college shall be eligible to
appear at B.Pharm final year examination of the University.
shall be same as prescribed for practical class in respective practical subject. Each practical
test may be conducted in different parts, viz., synopsis/spotting, exercise/experiment and viva-
voce etc.
(c) The regular record of marks of sessional examinations and that of professional training as well as of
project conducted at an affiliated college shall be maintained for each student and that must be
submitted to the university before the commencement of university examination.
(d) A candidate failing in any of the subjects shall have a chance to improve his / her sessional marks
both in theory and practical by appearing in one additional sessional examination. The aggregate of
best two performances from all the sessionals shall form the basis of calculating the average for
computation of improved sessional marks. Marks for day to day assessment in the practicals cannot
be improved unless a candidate attends a regular course of study again.
6. University Examination:
There shall be a main and a supplementary university examination in a year for B.Pharm first year, second
year, third year and final year. Main examination shall be held in the month of March/April or on such dates
as may be fixed by the University. Supplementary examination shall be conducted within 30 days of the
declaration of the result or on such dates as may be fixed by the university.
Marks for professional training shall be awarded on the basis of training report, interview and viva
voce by a board consisting of training in-charge and one examiner (appointed by the Head of the
institution) and the Head of the institution or his nominee who shall be the chairman of the board.
b) Project:
Before the end of B.Pharm Part-III, for each candidate, a project supervisor shall be appointed by
the Head of the institution. The candidate shall choose a project topic in consultation with the
supervisor. A synopsis on the project topic should be prepared in the prescribed format and
submitted to the Head of the institution for approval. Candidate shall carry out literature survey on
the approved topic during B.Pharm Part-IV under the guidance of the supervisor.
Candidate shall prepare three copies of his / her project report in prescribed format printed or type
written in bound form. One copy is to be submitted to the institute and one to the supervisor on or
before the prescribed date for evaluation and one copy to be retained by the candidate for his/her
own reference. The project report should contain a copy of approved synopsis and certificate from
the supervisor, certifying that the work has been undertaken and written under his/her supervision
and guidance and meets the requirements of the course, countersigned and duly forwarded by the
Head of the institution.
Marks for project shall be awarded on the basis of project report, seminar and viva voce by a board
consisting of supervisor, one examiner (appointed by the Head of the institute) and the Head of the
institute or his nominee who shall be the chairman of the board.
8. Conditions of Passing:
(a) No candidate shall be declared as having passed in a subject unless he / she has secured 50% of
the maximum marks in the university and sessional examination marks put together in each theory
and practical subject. Each theory and practical shall be considered as separate subject. In
B.Pharm final year, professional training and project shall be considered as separate subjects.
(b) A candidate who has failed in more than three subjects in B.Pharm first year examination will not be
allowed to pursue courses for B.Pharm second year. Such candidate will be allowed to appear as
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 3
an ex-student in the university examination of subsequent batch of B.Pharm first year in the failing
subjects.
(c) A candidate who has failed in not more than three subjects in B.Pharm first year examination will be
allowed to appear in the supplementary examination of B.Pharm first year in the failing subjects.
Candidates failing in any subject in the supplementary examination will be allowed to appear as an
ex-student in the university examination of subsequent batch of B.Pharm first year in the failing
subjects.
(d) A candidate who has passed in all the subjects of B.Pharm first year will be promoted to B.Pharm
second year.
(e) A candidate who has failed in more than three subjects in B.Pharm second year examination will
not be allowed to pursue courses for B.Pharm third year. Such candidate will be allowed to appear
as an ex-student in the university examination of subsequent batch of B.Pharm Part-II in the failing
subjects.
(f) A candidate who has failed in not more than three subjects in B.Pharm second year examination
will be allowed to appear in the supplementary examination of B.Pharm second year in the failing
subjects. Candidates failing in any subject in the supplementary examination will be allowed to
appear as an ex-student in the university examination of subsequent batch of B.Pharm second year
in the failing subjects.
(g) A candidate who has passed in all the subjects of B.Pharm second year will be promoted to
B.Pharm third year.
(h) A candidate who has failed in more than three subjects in B.Pharm third year examination will not
be allowed to pursue courses for B.Pharm final year. Such candidate will be allowed to appear as
an ex-student in the university examination of subsequent batch of B.Pharm third year in the failing
subjects.
(i) A candidate who has failed in not more than three subjects in B.Pharm third year examination will
be allowed to appear in the supplementary examination of B.Pharm third year in the failing subjects.
Candidates failing in any subject in the supplementary examination will be allowed to appear as an
ex-student in the university examination of subsequent batch of B.Pharm third year in the failing
subjects.
(j) A candidate who has passed in all the subjects B.Pharm third year will be promoted to B.Pharm
final year.
(k) A candidate who has failed in more than three subjects in B.Pharm final year examination will be
allowed to appear as an ex-student in the university examination of subsequent batch of B.Pharm
final year in the failing subjects.
(l) A candidate who has failed in not more than three subjects in B.Pharm final year examination will
be allowed to appear in the supplementary examination of B.Pharm final year in the failing subjects.
Candidates failing in any subject in the supplementary examination will be allowed to appear as an
ex-student in the next university examination of B.Pharm final year in the failing subjects.
(m) A candidate, who is unable to appear at any examination in any subject(s) due to any reason
whatsoever, shall be considered as having failed in that subject(s).
(n) In no case, will a candidate, who has not passed finally after 8 academic years from the year of
admission, will be allowed to continue the course.
(a) After passing the final examination, a candidate shall be awarded B.Pharm degree.
(b) The division to a successful candidate shall be awarded on the basis of aggregate of marks
obtained by him / her in B.Pharm first year, B.Pharm second year, B.Pharm third year, and B.Pharm
final year examinations regardless of the number of attempts, as shown below:
(c) The division to a successful candidate admitted directly to B.Pharm second year, shall be awarded
on the basis of aggregate percentage of marks obtained in B.Pharm second year, B.Pharm third
year and B.Pharm final year examinations regardless of the number of attempts.
(d) Rank shall be conferred on the basis of aggregate percentage of marks obtained in all the four
years to those candidates who have passed the whole examination in first attempt. For those
admitted directly to B.Pharm second year, the rank shall be conferred on the basis of aggregate
percentage of marks obtained in all the three years to those candidates who have passed the whole
examination in first attempt.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 5
* Professional training to be carried out for 400 Hrs as per clause 7 of academic regulations.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 7
Unit-I
1. Structure and properties: Atomic structure, atomic orbitals, valance bond theory, molecular orbital theory,
wave equation, molecular orbital, bonding and anti-bonding orbitals, covalent bonds, hybrid orbitals,
intermolecular forces, bond dissociation energy, polarity of bonds, polarity of molecules, structure and
physical properties, intermolecular forces.
2. Accuracy & precision: Accuracy and precision, classification of errors, minimization of errors, rejection of
doubtful values, significant figures & computations.
3. Acids, Bases and Buffers: Acids & bases : Hydrochloric Acid, Sulphuric Acid, Nitric Acid, Phosphoric Acid,
Sodium Hydroxide, Strong Ammonia Solution. Buffers: An introduction, pharmaceutical buffer selection,
pharmaceutical buffer system
4. Sources of impurities in pharmaceutical substances.
An outline of preparation, properties, uses, tests for purity and identification, including limit tests for Iron,
Arsenic, Lead, Heavy metals, Chloride, Sulphate and the special tests if any, of the following classes of
inorganic pharmaceuticals included in the Indian Pharmacopoeia 1996.
Unit-II
5 Gastrointestinal agents: Acidifying agents: Dilute hydrochloric acid.
Antacids: Sodium bicarbonate, Aluminum hydroxide gel, Calcium carbonate, Tri basic calcium phosphate,
Milk of magnesia, Magnesium oxide, Magnesium trisilicate.
Protective and adsorbents: Bismuth subcarbonate, Bismuth subnitrate, Kaolin, Activated charcoal.
Cathartics: Sodium carboxy methylcellulose, Bisacodyl, Sodium phosphate, Potassium sodium tartrate.
6 Topical agents: Protectives: Talc, Zinc oxide, Calamine, Zinc stearate, Titanium dioxide.
Astringents: Alum, Aluminium Sulphate.
Anti-microbial agents: Hydrogen peroxide, Potassium permangnate, Iodine, Silver nitrate, Boric acid,
Chlorinated lime, Borax, Sodium antimony gluconate.
7. Complexing and chelating agents: Disodium edetate, Dimercaprol.
Unit-III
8. Major intra - and extra-cellular electrolytes: Major physiological ions. Electrolytes used for replacement
therapy, acid-base balance and electrolyte combination therapy - Sodium chloride and its preparations,
Potassium chloride and its preparation, Calcium chloride, Calcium lactate, Calcium gluconate, Zinc Sulphate,
Sodium acetate, Potassium acetate, Sodium bicarbonate, Sodium dihydrogen phosphate dihydrate, Sodium
citrate.
9. Essential and trace elements: Transition elements and their compounds of pharmaceutical importance:
Iron and haematinic- Ferrous Sulphate, Ferrous gluconate, Ferrous fumorate, Iron-dextran injection, Ferric
ammonium citrate.
Mineral supplements.
10. Dental products: Dentrifrices, anti-caries agents- Sodium fluoride, Calcium carbonate, Dicalcium
phosphate.
Unit-IV
11. Miscellaneous agents: Sclerosing agents.
Expectorants- Ammonium chloride, Potassium iodide.
Emetics.
Antidotes- Sodium nitrite, Sodium Thiosulphate, Activated charcoal, Light Kaolin,
Anti-oxidants- Sodium metabisulphite, Sodium bisulphite.
Waters - Purified water, water for injection and sterile water for injection.
12. Inorganic radio pharmaceuticals: Nuclear radio pharmaceuticals, reactions, nomenclature, methods of
obtaining their standards and units of activity, measurements of activity (G.M. counters), clinical applications
and dosage, hazards and precautions & radioimmuno assay.
Biological applications of radioactive drug: cobalt compounds, gold compounds., iodine preparations,
phosphorous preparations. Radio opaque contrast media Barium Sulphate.
Unit-V
14. Titrimetric analysis – Theoretical considerations, classification of reactions in titrimetric analysis, standard
solutions, primary and secondary standards.
Aqueous acid – base titration – Neutralization, indicators, universal indicators, assay of sodium
bicarbonate, sodium carbonate, ammonia solution, boric acid, ammonium chloride.
Oxidation – reduction titrations including iodometry & iodimetry – Introduction, determination of the end
point in oxidation reduction titrations, assay of ferrous sulphate, hydrogen peroxide solution, iodine solution,
chlorinated lime and copper-sulphate.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 8
Unit-I
1. Foundation of biochemistry: Cellular, chemical, physical, genetic, evolutionary, transport process across
cell membrane.
2. Enzymes: Properties, Nomenclature, Classification, Mechanism of action, kinetics, Michaelis Menten
equation, enzyme inhibition, factor affecting enzyme action, iso-enzymes, co-enzymes, metaloenzymes,
allosteric-enzymes, regulatory enzymes, clinical and therapeutic uses of enzymes.
Unit-II
3. Vitamins: Classification and biological importance of vitamin A, vitamin D, vitamin E, vitamin K, vitamin B-
complex and ascorbic acid.
4. Carbohydrates: Properties, classification, metabolism-glycolysis, citric acid cycle, hexose monophosphate
shunt, uronic acid pathway, glucogenesis, glycogenolysis, glyconeogenesis, glyoxylate cycle, regulation of
metabolism, metabolism of fructose, galactose, abnormalities of carbohydrate metabolism, qualitative
identification tests.
Unit-III
5. Lipids: Properties, classification, storage of lipids, structural lipids in membranes, lipids as signals, cofactors
and pigments, digestion, mobilization and transport of fats, oxidation of glycerol, oxidation of fatty acids,
ketone bodies, biosynthesis of fatty acids, eicosanoids, triglycerides, phosphnolipids, cholesterol, steroids,
isoprenoids, regulation of fatty acids metabolism, phospholipids, sphingolipids, eicosanoids, abnormalities of
lipid metabolism, qualitative identification tests.
6. Biological oxidation: Redox-potential, enzymes and co-enzymes involved in oxidations, reduction and its
control, respiratory chain, its role in energy capture and its control, energetics, and mechanism of oxidative
phosphorylation, inhibitors of respiratory chain.
Unit-IV
7. Amino acids, peptides and proteins: Properties, structure, classification, three-dimensional structure of
proteins – primary, secondary, tertiary and quaternary, functions of protein-reversible binding of protein to a
ligand, complementary interactions between proteins and ligands, protein interactions modulated by
chemical energy, catabolism of amino acids, biosynthesis of amino acids, urea cycle, biosynthesis of
porphyrin and bile pigments, regulation and abnormalities of metabolism of amino acids, peptides and
proteins, qualitative identification test of amino acids and proteins.
8. Nucleic acids: Brief introduction of genetic organization (genes and chromosomes), structure and chemistry
of nucleic acids, biosynthesis of purine and pyrimidine, biosynthesis and degradation of nucleotides,
biosynthesis and replication of DNA, biosynthesis of RNA, mutagenesis, qualitative identification test of RNA
and DNA.
Unit-V
9. Genetic code and protein biosynthesis: Genetic code, protein biosynthesis and its inhibition, regulation of
gene expression – principles, regulation in prokaryotes and eukaryotes.
1. Qualitative identification test for carbohydrates, lipids, proteins, amino acid and nucleic acids.
2. Quantitative estimation of amino acids.
3. Quantitative estimation of proteins.
4. Identification of c-terminal amino acids of protein.
5. Determination of glucose by means of enzyme glucose oxidase.
6. Isolation and assay of glycogen from the liver and skeletal muscle of rats.
7. Enzyme hydrolysis of glycogen by alpha and beta amylases.
8. Isolation and determination of RNA and DNA.
9. Effect of temperature on activity of alpha amylase.
10. Estimation of SGOT, SGPT, ALP and BRN in the serum.
11. Examination of sputum and faeces (microscopic & staining).
12. Practice in injecting drugs by intramuscular, subcutaneous and intravenous routes, Withdrawal of blood
samples.
Unit-I
1. Introduction: Definition, general dispensing procedure, introduction to different dosage forms with
examples, sources of information including different pharmacopoeias, labeling of different preparations,
containers and closures, storage, Latin terms.
2. Prescription: Definition, various parts, handling and sources of errors.
Unit-II
3. Pharmaceutical calculations: Metric system (weights and measures), enlarging and reducing of recipes,
isotonic solutions, alcohol dilutions, alligation method, proof spirit, percentage solution, displacement value.
4. Posology: Definition, factors influencing doses, calculation of doses.
Unit-III
5. Incompatibility: Definition, physical, chemical (including double decomposition and other chemical
reactions), therapeutic and methods of correction.
Unit-IV
6. Principles involved and procedure adopted in dispensing of: Typical prescriptions like mixtures, syrups,
elixirs, linctuses, liniments, lotions, collodions, gargles, mouthwashes, throat paints, douches, enemas,
eardrops, nasal drops, nasal sprays, inhalations, ophthalmic and sterile dosage forms.
Unit-V
7. Principles involved and procedure adopted in dispensing of: Typical prescriptions like suspensions,
emulsions, ointments, creams, pastes, jellies, poultices, suppositories, powders, pills, pastilles, lozenges,
capsules, granules, cachets, tablet triturates and compressed tablets.
1. Dispensing of prescriptions falling under the categories: Mixtures, solutions, emulsions, creams, ointments,
powders, suppositories, ophthalmics, capsules, pastes, jellies, pastilles, lozenges, pills, tablet triturates,
lotions, liniments, inhalations, paints, etc.
2. Identification of various types of incompatibilities in prescriptions, correction thereof and dispensing of such
prescriptions.
3. Dispensing procedures involving pharmaceutical calculations, pricing of prescriptions and dosage
calculations for pediatric and geriatric patients.
4. Dispensing of prescriptions involving adjustment of tonicity.
5. Categorization and storage of pharmaceutical products based on legal requirements of labeling and storage.
6. Project report on visit to the nearby community for counseling on the rational use of drugs and aspects of
health care.
Unit-I
1. Semisolid Dosage Forms: Definitions, types, mechanisms of drug penetration, factors influencing
penetration, semisolid bases and their selection, general formulation of semisolid bases, clear gels
manufacturing procedure, evaluation and packaging.
2. Suppositories: Ideal requirements, bases, manufacturing procedure, packaging and evaluation.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 10
Unit-II
3. Extraction and galenical products: Principle and method of extraction, percolation, maceration, continuous
hot extraction, preparation of infusion, tincture, dry and soft liquid extracts.
Unit-III
4. Liquid Dosage Forms: Introduction, types of additives used in formulations, Vehicles, stabilisers,
preservatives, suspending agents, emulsifying agents, solubilisers, colors, flavours and the others,
manufacturing packaging and evaluation of clear liquids, suspensions and emulsions official in
pharmacopoeia.
Unit-IV
5. Pharmaceutical Aerosols: Definition, propellants, general formulation, method of preparation, packaging
and containers, evaluation
6. Ophthalmic preparations: Requirements of formulation, methods of preparation, containers, evaluation.
Unit-V
7. Blood Products and Plasma Substitutes: Collection, processing of storage of whole human blood,
concentrated human RBCs, dried human plasma, human fibrinogen, human normal immunoglobulins,
human fibrin foam, plasma substitutes- ideal requirements, PVP, dextrans etc.
1. Preparation, evaluation and packaging of liquid orals like solutions, suspensions and emulsions, ointments,
suppositories, aerosols, eye drops, eye ointments etc.
2. Preparation of pharmacopoeial extracts and galenical products utilizing various methods of extraction.
3. Collection processing, storage and fractionation of blood.
Unit-I
1. Scope and significance of biology in pharmaceutical sciences. Methods of classification of plants.
2. Plant cell, its structure and non-living cell inclusions; mitosis and meiosis; different types of plant tissues and
their functions. Morphology, histology and uses different part of such as root, stem, bark, wood, leaf, flower,
fruit and seeds.
3. Techniques in microscopy: Various tools used in microscopy (microscopes, micrometers, camira lucida,
microphotography etc.,) preparation of drugs for microscopical examination, general use of different reagents
used in microscopy. Quantitative microscopy: Lycopodium spore method and leaf constants viz. stomatal
number, stomatal index, vein-islet number, vein-termination number and palisade ratio.
Unit-II
4. Plant taxonomy: Study of the following families with special reference to medicinally important plants-
Apocynacae, Solanaceae, Rutaceae, Umbelliferae, Leguminosae, Rubiaceae, Liliaceae, Graminae,
Labiatae, Cruciferae, Papaveraceae. Cultivation, collection, processing and storage of crude drugs. Factors
influencing cultivation of medicinal plants. Types of soils and fertilizers of common use. Pest management
and natural pest control agents.
Unit-III
5. Definition, history, scope and development of Pharmacognosy. Sources of drugs: Biological, marine, mineral
and plant tissue cultures as sources of drugs. Classification of drugs: Alphabetical, morphological,
taxonomical, chemical and pharmacological classification of drugs.
6. Carbohydrates and derived products: Agar, guar gum, acacia, honey, isabgol, pectin, starch, sterculia
and tragacanth.
Unit-IV
7. General survey of animal kingdom; structure and life history of parasites like amoeba, entamoeba,
trypanosoma, plasmodium, taenia, ascaris and schistosoma. General structure and life history of insects like
mosquito, housefly, mites and silkworm.
8. Lipids: Bees wax, castor oil, cocoa butter, cod-liver oil, hypnocarpus oil, kokum butter, lard, linseed oil, rice
bran oil, shark liver oil and wool fat.
Unit-V
9. Quality control of crude drugs: Adulteration of crude drugs and their detection by organoleptic,
microscopic, physical, chemical and biological methods of evaluation. An introduction to active constituents
of drugs: Their isolation, classification and properties.
10. Plant hormones and their application. Polyploidy, mutation and hybridization with reference to medicinal
plants.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 11
Unit-I
1. Scope of anatomy & physiology, definition of various terms used in Anatomy.
Structure of cell, functions of its components.
Elementary tissues of human body: epithelium, connective, muscular and nervous.
Structure and functions of skeleton & joints: classification, movement and disorders of joints.
2. Skeletal muscles: name, position and functions of various muscle: Neuromuscular junction: Physiology of
muscle contraction.
Unit-II
Blood: Composition and functions of blood elements, blood group and coagulation of blood.
Lymph nodes: Their position, name and functions. Lymph: Its composition and functions.
3. Cardiovascular system: Structure and functioning of Heart: Heart sounds, cardiac cycle various blood
vessels: Arteries supplying to different parts and veins collecting blood from different parts. Blood pressure
and its regulation.
Unit-III
4. Digestive system: Gross Anatomy and functions of various parts of alimentary canal including pancreas
and liver. Composition and functions of various juices used in digestion. Role of vitamins in body.
Respiratory system: Anatomy of various parts of respiratory system. Physiology and regulation of
respiration.
Unit-IV
Urinary system: Various parts of urinary system. Structure and functions of Kidney. Physiology of urine
formation.
5. Nervous system: Brain and spinal cod: Structure and functions of different parts. Reflex action. Physiology
of nerve impulse transmission. Nerves: Cranial and spinal nerves: Anatomy and physiology of Autonomic
nervous system. Neurotransmitters: Name, their release and physiological role
Reproductive system: Male and female reproductive organs: their position and functions.
Unit-V
6. Endocrinal glands: Names, position and functions. Physiological role of hormones secreted by various
glands viz. Adrenal, Thyroid, Parathyroid, Pituitary, Pancreas, Thymus, Ovary and testis.
Elementary knowledge of sense organs for taste, smell, vision and hearing. Skin: structure and functions.
7. Health education: Concept of health and disease, Definition, Dimensions and determinants of health,
indicators of health, balanced diet, First aid treatment of shock and snake bite. Family Planning,
Immunization schedule, concept of prevention of diseases, modes of intervention, Common infectious
diseases and their prevention.
Unit-I
1. Origin, development, scope, objectives and nature of pharmaceutical legislation in India. Evolution of the
“Concept of Pharmacy” as an integral part of the health care system.
Principles and significance of professional ethics. Critical study of the code of pharmaceutical ethics drafted
by Pharmacy Council of India. Pharmaceutical education - A brief review.
Pharmacy Act, 1948 – The general study of the Pharmacy Act with special reference to Education
Regulations, working of State and Central Councils, constitutions and functions of these councils, registration
procedures under the Act.
Unit-II
2. The Drugs and Cosmetics Act, 1940 & Rules 1945 – General study of the Drugs and Cosmetics Act and the
Rules there under. Definitions and salient features related to retail and wholesale distribution of drugs. The
powers of inspectors, the sampling procedures and the procedure and formalities in obtaining licences under
the rule. Facilities to be provided for running a Pharmacy effectively. General study of the schedules with
special reference to schedules C, C1, F, G, J, H, P and X and salient features of labeling and storage
conditions of drugs.
Unit-III
3. An elaborate study of the following (as amended to date)
(a) Drugs (Price Control) Order
(b) Medicinal and Toilet Preparations (Excise Duties) Act, 1955
(c) Poisons Act 1919
(d) Patents Act 1970
Narcotic Drugs and Psychotropic Substances Act, 1985 – A brief study of the Act with special reference to its
objectives, offences and punishment.
Unit-IV
4. A brief study of the following with special reference to the main provisions (as amended to date)
(a) Medical Termination of Pregnancy Act, 1970 & Rules 1975
(b) Prevention of Cruelty to Animals Act, 1960
(c) Essential Commodities Act
The Drugs and Magic Remedies (Objectionable Advertisement) Act, 1954 – General study of the Act,
objectives, special reference to be laid on advertisements, magic remedies and objectionable and permitted
advertisement and diseases which cannot be claimed to be cured.
Unit-V
5. A brief study of the following with special reference to the main provisions
(a) States Shops and Establishments Act & Rules.
(a) Factories Act, 1948
(b) Minimum Wages Act, 1948
Unit-I
1. Introduction: Trade, industry and commerce, functions and subdivision of commerce.
Forms of business organizations.
Drug house management: Selection of location of drug store, layout and legal requirements, chain store.
2. Material management: Importance and objectives of purchasing, selection of suppliers, credit information,
tenders, contracts and price determination and legal requirements thereto.
Storage: General principles, codification, handling of drug store and other hospital supplies.
Inventory control: Objectives and importance, modern techniques like ABC, VED analysis, the lead time,
inventory carrying cost, safety stock, minimum and maximum stock levels, economic order quantity, scrap
and surplus disposal.
Unit-II
3. Sales promotion: Salesmanship, qualities of salesman, literature detailing, advertising and window display.
Recruitment, selection, orientation, training, evaluation and compensation of the Pharmacist.
4. Channels of distribution, buying, selling, transportation, storage, wholesale, retail, departmental store,
multiple shop, mail order business with special reference to Indian marketing environment.
Unit-III
5. Banking and finance service and functions of bank, finance planning and sources of finance.
Cost accounting: Cost ascertainment, various elements of cost sheet preparation, statement of cost.
Unit-IV
6. Accountancy: Introduction to the accounting concepts and conventions, double entry book keeping,
different kinds of accounts, recording of transactions-journal, cash book, ledger, trial balance, profit and loss
account, balance sheet, computation of various ratios and analysis of financial statements.
Unit-V
7. Budgeting: Meaning importance and types of budgets. Elementary knowledge of preparing sales, cash,
production and flexible budgets.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 14
Unit-I
1. Stereochemistry: Isomerism, stereoisomerisms, optical activity, enantiomers, diastereomers, meso
compounds, chirality, racemic modification & its resolution, configuration (R&S, D&L, d&l), sequence rules,
conformational isomers.
Rotation about C-C single bond, conformation due to rotation, Vander waals repulsion, stereochemical
reaction (selective & specific), syn and anti addition and elimination.
Unit-II
2. Reactions: Definition, reaction, mechanism, applications of all the following reactions - SN1 & SN2 reactions,
E1 & E2, reactions, electrophilic & free radical addition reactions, markonikov rule and antimarkonikov rule.
Unit-III
3. Reactions: Definition, reaction, mechanism, applications of all the following reactions – aldol and claisen
condensations, Wittig reaction, wolf-kishner reduction, clemmensen reduction, cannizaro and crossed
cannizaro reaction, perkin condensation, Grignard synthesis, wurtz reaction, Williamson ether synthesis,
fischer esterification, Diels alder reaction.
4. Aromatic Compounds: Structure of benzene and its derivatives, aromaticity, resonance theory, stability of
benzene ring and huckle rule.
Unit-IV
5. Aliphatic compounds: Structure, nomenclature, preparation, physical properties and chemical reactions of
aliphatic compounds: dienes, α, β− unsaturated carbonyl compounds, cycloalkanes. Aliphatic and aromatic
alcohols, ethers, esters, carboxylic acids, aldehydes and ketones, phenols and amines.
Unit-V
6. Reactions: Electrophilic aromatic substitution, nucleophilic acyl substitution, friedal crafts alkylation and acylation,
kolbe’s synthesis, reimer tieman reaction, hoffmann reaction, Diazotization reaction and coupling reactions of
amines.
7. Poly nuclear hydrocarbons: Structure, nomenclature, preparation and reactions οφ− naphthalene, anthracene and
phenanthrene.
Unit-I
1. Heterocyclic Compounds (Single and fused rings): Structure, nomenclature, preparations, chemical
reactions of pyrrole, furan, thiophene, imidazole, pyrazole, pyridine, piperazine, pyrimidine, purine, indole,
benzimidazole, quinoline, isoquinoline (important medicinal derivatives under each class should be
discussed)
Unit-II
2. Carbohydrates: Structure, detailed chemistry, properties and reactions of mono, di and poly saccharides
and qualitative analysis of carbohydrate.
3 Cardiac Glycosides Source, chemistry, biogenesis and pharmacological activity of digitoxin, digoxin,
diosgenins, strophanthidin and sennosides.
Unit-III
4 Lipids: Classification & composition of fats and oils, properties, determination and significance of acetyl
value, acid value, saponification and iodine value.
5 Amino acids, Peptides and proteins: Structure, classification, properties & reactions of amino acids,
nomenclature of peptide and protein, solid phase peptide synthesis, classifications of proteins and levels of
protein structure and protein denaturation.
Unit-IV
6. Nucleic acids: Nucleosides & nucelotides structure of RNA and DNA and biological importance of nucleic
acids.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 15
7. Terpenoids & Terpenes: Sources, classification and structural elucidation and pharmacological activity of
menthol, camphor, citral.
8. Antibiotics: Source, chemistry and therapeutic activity of natural penicillins, streptomycins and tetracyclines.
Unit-V
9. Alkaloids: Source, general classifications, chemistry and structural elucidation and pharmacological activity
of atropine, quinine, reserpine, morphine, papavarine, ephedrine, ergot and vinca alkaloids.
10. Lignans and Flavonoids: Chemistry and biogenesis of medicinally important lignans and flavonoids.
11. Vitamins: Source, chemistry and uses of vitamins of plant origin.
1. Synthesis of heterocyclic compounds like coumerine, furan derivatives, barbiturate and other related
heterocyclic compounds.
2. Qualitative analysis of natural products like carbohydrates, proteins, fats, alkaloids, glycosides.
3. Analysis of fats and oils (acid value, iodine value, acetyl value, ester value, saponification value.
Unit-I
1. Matter, properties of matter: State of matter, change in the state of matter, latent heats and vapor
pressure, sublimation-critical point, eutectic mixtures, gases, aerosols-inhalers, relative humidity, liquid.
Complexes, liquid crystals, glassy state, solids-crystalline, amorphous and polymorphism. Thermal
analysis(DSC,DTA,TGA)
2. Behaviour of Gases: Kinetic theory of gases, deviation from behaviours and explanation.
3. Kinetics and drug stability: General considerations and concepts, half – life determination, influence of
temperature, light, solvent, catalytic species and other factors, accelerated stability study, expiration dating.
4. Diffusion and Dissolution: Diffusion, dialysis, ultra-filtration, fick 's first law of diffusion, fick's second law of
diffusion, dissolution rate, powder dissolution-hixson crowell cube root law, drug release from polymer and
granular matrices, diffusion of drug through GIT membrane, pH partition hypothesis
Unit-II
5. Dispersion systems: Colloidal dispersions: Definition, types, properties of colloids, protective colloids,
applications of colloids in pharmacy; Suspensions and emulsions: Interfacial properties of suspended
particles, settling in suspensions, theory of sedimentation, effect of brownian movement, sedimentation of
flocculated particles, sedimentation parameters, wetting of particles, controlled flocculation, flocculation in
structured vehicles, rheological considerations, Donnan membrane equilibrium; Emulsions-types, theories,
physical stability.
Unit-III
6. Complexation: Classification of complexes, methods of preparation and analysis, applications.
7. Buffers: Buffers equations and buffer capacity in general, buffers in pharmaceutical systems, preparation,
stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting
isotonicity. Henderson Hesselbalch equation, influence of solvents on the solubility of drugs, combined effect
of pH and solvents, preservation, action of weak acids, distribution of solutes between immiscible solvents,
effect of ionic dissociation and molecular association on partition co-efficient & drug action.
Unit-IV
8. Surface and interfacial phenomenon: Liquid interface, surface and interfacial tensions, surface free
energy, measurement of surface and interfacial tensions, spreading coefficient, adsorption at liquid
interfaces, surface active agents, HLB classification, solubilization, detergency, adsorption at solid interfaces,
solid-gas and solid-liquid interfaces, complex films, electrical properties of interface.
9. Viscosity and rheology: Newtonian systems, law of flow, kinematic viscosity, effect of temperature, non-
Newtonian systems, pseudoplastic, dilatant and plastic flow; thixotropy in formulation, determination of
viscosity; capillary, falling ball, rotational viscometers.
Unit-V
10. Micromeritic and powder rheology: Particle size and distribution, average particle size, number and
weight distribution, particle number, methods for determining particle volume, optical microscopy, sieving,
sedimentation, measurement, particle shape, specific surface, methods for determining surface area,
permeability, adsorption, derived properties of powders, porosity, packing arrangement, densities, bulkiness
and flow properties.
11. Solubility & distribution phenomenon: Solubility, factors affecting solubility, expression of solubility,
dissolution rate, solvent-solute interaction, polar and non-polar solvents, solubility of gases in liquid, liquid in
liquid, effect of pressure, temperature, salting-out, chemical reasons, solubility calculations, ideal and real
solution, colligative properties and mol. wt. determinations, miscibility, influence of foreign substances,
dielectric constant and solubility, solubility of solid in liquids, ideal and non ideal solutions, solution and
association in solution, solubility of slightly soluble and electrolytes.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 16
B.Ph. 207T Pharmaceutical Engineering, Unit Operations and Engineering Drawing 75 Hrs
Unit-I
1. Unit Operations: Introduction, basic laws.
2. Material of construction: General study of composition, corrosion, resistance, Properties and applications
of the materials of construction with special reference to glass, plastics and metals, corrosion.
3. Material Handling Systems:
a. Liquid handling – Different types of pumps.
b. Gas handling – Various types of fans, blowers and compressors.
c. Solid handling – Different types of conveyers.
Unit-II
4. Fluid Flow: Types of flow, Reynolds number, Bernoulli’s theorem, energy losses, basic equation of fluid
flow, valves, measurement of flow.
5. Filtration and centrifugation: Theory of filtration, factors affecting filtration, filter aids, filter media, industrial
filters including filter leaf, filter press, rotary filter, edge filter. Principles of centrifugation, industrial centrifugal
filters and centrifugal sedimenters.
6. Size reduction, size separation, drying, compression and compaction.
Unit-III
7. Dehumidification and humidity control: Basic concepts and definition, wet bulb and adiabatic saturation
temperatures, Psychrometric chart and measurement of humidity, application of humidity measurement in
pharmacy, equipments for dehumidification operations.
8. Refrigeration and air conditioning: Principal and applications of refrigeration and air conditioning.
9. Heat Transfer: Applications, modes of heat transfer, Fourier’s law, film coefficients, Boltzmann’s law, heat
exchangers and heat interchangers.
Unit-IV
10. Evaporation: Theory, factors affecting evaporation, efficiency of evaporators, natural circulation types –
evaporating pans and stills, short tube evaporators, forced circulation type – long tube evaporators, wiped
film evaporators, evaporation under reduced pressure.
11. Distillation: Theory and applications, simple distillation, flash distillation, fractional distillation, steam
distillation, molecular distillation, azeotrope distillation, distillation under reduced pressure. Preparation of
purified water IP and WFI IP, construction and working of the still used for the same.
12. Mixing: Theory of mixing, solid-solid mixing, solid-liquid and liquid-liquid mixing, mixing of semisolids,
equipments used in mixing.
Unit-V
13. Crystallization: Theory of crystallization, characteristics of crystals like-purity, size, shape, geometry, habit,
forms size and factors affecting them, solubility curves and calculation of yields, study of various types of
crystallizers – agitated batch crystallizer, Swenson walker crystallizer, krystal crystallizer, vacuum
crystallizer, caking of crystals and its prevention.
14. Industrial Hazards and Safety Precautions: Mechanical, chemical, electrical, fire and dust hazards and
accident records.
15. Automated process control systems: Introduction to automatic process system and elements of automatic
process control, measurement of variables like temperature, pressure level and vacuum.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 17
B.Ph. 208P Pharmaceutical Engineering, Unit Operations and Engineering Drawing 75 Hrs
1. Measurement of flow of fluids and their pressure, determination of Reyonld’s number and calculation of
frictional losses.
2. Evaluation of filter media, determination of rate of filtration and study of factors affecting filtration.
3. Experiments to demonstrate applications of centrifugation.
4. Thermometers and psychrometric charts, determination of humidity – use of dry bulb and wet bulb.
5. Determination of overall heat transfer coefficient.
6. Experiment to study the influence of various parameters on rate of evaporation.
7. Experiments based on steam, extractive and azeotropic distillation.
8. Determination of rate of drying, free moisture content and bound moisture content.
9. Experiments to illustrate principles of size reduction and size separation, laws governing energy and power
requirements of size reduction.
10. Experiments to illustrate solid-solid mixing, determination of mixing efficiency using different types of mixers.
11. Basic engineering drawing practice; drawing of simple pharmaceutical machinery parts – bolts, nuts, riveted
fronts, screws, worn screws as per specification.
Unit-I
1. General Pharmacology: Introduction to pharmacology, sources of drugs, dosage forms. Routes of
administration, mechanism of drug action, dynamic of drug absorption, distribution, metabolism and
excretion. Theories of receptors, dose response relationship, affinity constants.
2. Factors affecting dose and effect of a drug. Adverse drug reactions, drug interactions. Drug evaluation.
Unit-II
3. Autocoids:
a. Histamine, 5HT and their antagonists.
b. Prostaglandins, Thromboxanes and Leukotrienes, Platelet activating factors.
c. Pentagastrin, Cholecystokinin, Angiotensin, Bradykinin and substance P.
d. Nitric oxide.
e. Free radicals.
4. Endocrine system:
a. Hypothalmic hormone and Pituitary hormones.
b. Thyroid and anti thyroid drugs, Parathormone, Calcitonin.
c. Corticosteroids.
d. Gonadal hormones (sex hormones) and their antagonists.
e. Drugs affecting calcium balance.
f. Insulin, oral hypoglycaemic agents and glucagons.
g. Oxytocic drugs and uterine relaxants.
Unit-III
5. Drugs acting on Peripheral nervous system:
a. Skeletal muscle relaxants.
b. Local anaesthetics.
Unit-IV
7. a. C.N.S. stimulants and cognitive enhancers.
b. Antiparkinson drugs.
c. Psycopharmacological drugs (antipsychotics, antianxiety, anti-depressants)
d. Drugs used in gout and rheumatoid arthritis.
8. Pathophysiology of following diseases: Rheumatoid arthritis, gout, epilepsy, psychosis, depression, mania.
Unit-V
9. Pathophysiology of following common diseases: Basic principle of cell injury and adaptation: Causes of
cellular injury, pathogenesis, morphology of cell injury. Intercellular alterations in lipids, proteins and
carbohydrates, cellular adaptation, atrophy and hypertrophy.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 18
Basic mechanism involved in the process of inflammation and repair: Alterations in vascular permeability and
blood flow, migration of WBCs, acute and chronic inflammation, mediators of inflammation, brief outline of
the process of repair.
Unit-I
1. Data, Need of Data Processing, Information & its Need, Levels of information, Quality of information,
Comparison of manual & electronic storage of data.
Introduction to computer: Brief history of development of computers, computer system concept, computer
system characteristics, capabilities and limitations, Applications in general and pharmacy in particular.
Elements of computer systems: The architecture of a computer system, CPU – ALU, CU, Memory – Primary
and Secondary, Input/Output and Storage Devices - Keyboard, Magnetic Tape, Magnetic Disk, Monitor,
Printer, Floppy Disk, Hard Disk.
2. Peripheral devices — mouse, OCR, OMR, MICR, scanner, monitor, Printers – impact and non-impact
printers – DMP, daisy wheel, line and drum printers, ink-jet and laser printers, plotters. Types of computers –
Analog, Digital, Hybrid, General, Special, Purpose, Micro, Mini, Mainframe, Super, Personal computer (PCs)
– Configuration, Pentium and Newer PCs specifications and main characteristics, types of PCs – Desktop,
Laptop, Notebook, Palmtop, Workstations etc. – their characteristics.
Unit-II
3. Software, Types of Software – System Software, Application Software, Introduction to operating systems
MS-DOS, Windows, Linux etc. Concept of programming, programming languages. Types of computer
languages, Machine, Assembly, high level language. Examples & areas of use of various high level
language & their features. Language translators : Comparative study, assembler, compiler, Interpreter.
Introduction to networking, concept of LAN and WAN. Internet Technology : Concept, e-mail services,
browsers, search engines, WWW, HTML, Introduction to e-commerce, advantages & growth.
Unit-III
4. Windows 95/98: Windows concepts, Features, Windows Structure, Desktop, Taskbar, Start menu, My
Computer, Recycle Bin, Windows Accessories – Calculator, Notepad, Paint, Wordpad, Character Map,
Windows Explorer, Entertainment, Managing Hardware & Software, System Tools, Communication, Sharing
Information between programs. Word Processing : MS-Word — Features, Creating, Saving and Opening
Documents in Word, Interface, Toolbars, Ruler, Menus, Keyboard Shortcut, Editing, Previewing, Printing &
Formatting a Document, Advanced Features of MS Word, Find & Replace, Using Thesaurus, Using Auto –
Multiple Functions, Mail Merge, Handling Graphics, Tables & Charts, Converting a word document into
various formats like – Text, Rich Text format etc.
Unit-IV
5. Electronic Spread Sheet– MS–Excel — Worksheet basics, creating worksheet, entering data into worksheet,
heading information, data, text, dates, alphanumeric, values, saving & quitting worksheet, Opening and
moving around in an existing worksheet, Toolbars and menus, Keyboard shortcuts, Working with single and
multiple workbook, working with formulae & cell referencing, Auto sum, Coping formulae, Absolute & relative
addressing, Working with ranges, formatting of worksheet, Previewing & Printing worksheet, Graphs and
charts, Database, Creating and using macros, Multiple worksheets – concepts, creating and using.
6. Presentation Graphics (MS-PowerPoint) : introduction, various uses, creating and saving presentation,
creating slides – different types of slides, different views of slides, editing and formatting slides,
backgrounds, inserting pictures from files, presentation shows, animation, customization of slides.
Unit-V
7. Introduction to Databases with MS-Access: What is database, uses, hardware requirement, types, use of
form, reports, query and simple code generation.
8. Introduction to internet: History, requirements, e-mail, search engines, websites and webservers, basics of
html, scientific information retrieval using databases, search engines, pubmed, patent databases
3. Exercises based on electronic worksheet – creating sheet, entering data, applying formulae, functions on
cells etc.
4. Application of absolute and relative referencing on data
5. Creating reports based on the experiments done in laboratories.
6. Searching of scientific information using database Pubmed, Searching of scientific information from
patent databases, Searching of scientific information using search engines scholar.google.com and
scirus.com
7. E-mail, creating of account, drafting, sending, attachments
8. Database creation, modification, searching of information, data input using forms, report creation,
simple query process
Unit-I
1. Sets, relations and functions equation of straight line. Calculus of finite differences Finite different, difference
table finite difference operator and their properties.
2. Linear equation and matrices, solution of linear programming problems by graphical method and simplex
method.
Unit-II
3. Transportations and assignment problems. Theory of games, quening theory: One length, waiting time in
Poisson que.
Unit-III
4. Differential calculus limits continuity and differentiability. Differentiation: Basic fundamental theorems on
differentiation, differentiation of trigonometric and hyperbolic function (including inverse trigonometric and
hyperbolic function), logarithmic differentiation. Partial differentiation.
Unit-IV
6. Differential equations: Formation, order and degree of a differential equation. Differential equation of first
order and first degree, linear differential equation with constant coefficients. Homogeneous linear differential
equations.
7. Laplas and inverse laplas transforms and their properties. Evaluation of laplas and inverse laplas transforms
of simple functions (including higher transcedatal functions) Application of laplas and its inverse to solve
linear ordinary differential equation.
Unit-V
8. Bio-statistics: Tables and graphs 'Life tables' only, Linear correlation coefficient, Pearson's assumptions and
causality; Regression of Y on X and X on Y, standard error estimate, Correlation coefficient: Linear and
curvilinear correlation; Sampling: Non Probability and probability samples, Sampling distribution, confidence
intervals, computing 99% and 95% fiducial limits from tables of areas and ordinates of normal curve.
Probability rules, binomial experiments, 'Z' score computing 't' tests and analysis of variance. All calculation
should be illustrated with examples from true laboratory pharmacological experimental models.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 20
Unit-I
1. Pharmaceutical Analysis: Types of analytical methods, different types of instrumental methods and the
physical/chemical property used, data domains, criteria for analytical method selection, performance
characteristics of instruments viz. precision, bias, sensitivity, LOD, LOQ, LOL, selectivity, calibration of
instruments.
2. Non-aqueous Acid-base Titrations: Non-aqueous acid – base chemistry, solvents for non-aqueous
titrations, leveling solvents, indicators for non-aqueous titrations, determination of organic acid & base in non
aqueous media, assay of phenobarbitone, benzocaine, dapsone, sodium amino salicylate,
sulphamethoxazole, sulphathiazole etc.
3. Redox Titration: Theory of redox reaction, balancing the redox reaction equation, types of indicators in
redox titration, end-point determination in redox titration, iodometry, iodimetry, bromometry, Nernst equation,
electrodes and their types, potentiometric method of end-point determination, assay of FeSO4, H2O2, Iodine
solution, chlorinated lime, copper sulphate.
Unit-II
4. Complexometric Titration: Introduction, stability of complexes, factors influencing the stability of
complexes, types of E.D.T.A. titrations, assay of calcium gluconate, magnesium sulphate, zinc sulphate.
5. Precipitation Titration: Introduction, precipitation reactions, determination of endpoint in precipitation
reactions. assay of sodium chloride injection, yellow mercuric oxide.
Unit-III
6. Gravimetric Analysis: Introduction, precipitation methods, conditions of precipitation, filtration & washing of
the precipitate, drying and ignition of the precipitate, assay of sodium sulphate, magnesium sulphate.
7. Diazotization Titration: Introduction, theory of diazotization reaction, assay of sulfamethoxazole,
benzocaine, dapsone, sodium amino salicylate.
The theoretical aspects, basic instruments & applications of the following analytical techniques should be
discussed.
Unit-IV
8. Potentiometry and Conductometry
Unit-V
9. Amperometry, coulometry and polarography
Unit-I
1. Principles of medicinal chemistry: Physico-chemical aspects (solubility, partition coefficient, optical,
geometrical and bioisosterism, ionization, hydrogen binding, chelation, redox-potential and surface activity)
of drug molecule and biological action. Drug receptor interaction including transduction mechanism.
2. Drug metabolism: General pathways of drug metabolism, sites of drug biotransformation, role of
cytochrome P-450, oxidative reactions, reductive reactions, hydrolytic reactions, conjugation reactions, factor
affecting drug metabolism.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 21
Unit-II
3. Prodrug and drug latentiation: Basic concepts, prodrugs of functional groups, bioprecursor produrgs,
chemical delivery systems.
The following topics shall cover classification, nomenclature, S.A.R., synthesis, physicochemical
properties, metabolism and therapeutic uses of drugs mentioned under each category. (Biochemical
approaches in drug design wherever applicable should be discussed. A brief introduction of latest drugs
under each category should also be discussed)
5. Vitamins: Classification, detailed chemistry and biological importance of vitamin A, vitamin D, vitamin E,
vitamin K, vitamin B-complex and ascorbic acid.
Unit-III
6. Chemotherapetutic agents: Antimicrobial agents.
(i) Antiseptics and disinfectants: Chlorphene, hexachlorophene, povidone-iodine, chloramines-T,
thiomersal, benzalkonium chloride, cetyl pyridinium chloride, gentian violet, chlorhexidine, chlorxylenol,
chlorocresol.
(ii) Antibacterial:
Sulphonamides: Sulphacetamide, sulphadiazine, sulphadimidine, sulphafurazole, sulphamethoxazole,
sulphamethoxy pyridazine, succinyl sulphathiazole, phthalysulphathiazole, sulphaguanidine,
sulphisoxazole, sulfadoxine, salphasalazine.
Antibiotics: Beta-lactum antibiotics (penicillins and cephalosporines), aminoglycosides– streptomycin,
gentamycin, tobramycin, amikacin, tetracyclines, macrolides– erythromycin, roxithromycin, azithromycin,
quinolones – nalidixic acid, norfloxacin, ciprofloxacin, ofloxacin, sparfloxacin, levofloxacin, gemifloxacin
and miscellaneous– chloramphenicol, clindamycin, polymyxin, vancomycin, bacitracin, cycloserine.
Antitubercular agents: Isoniazid, rifampicin, pyrazinamide, ethambutol, streptomycin, ethionamide,
thiacetazone, PAS.
Antileprotic agents: Dapsone, clofazimine.
(iii) Antifungal agents: Amphotericin-B, Flucytosine, ketoconazole, itraconazole, fluconazole, voriconazole,
griseofulvin, clotrimazole, tolnaftate, naftifine, nystatin.
Unit-IV
(iv) Antiviral and anti-HIV agents: Vidarabiine, Acyclovir, cidofovir, famciclovir, foscarnet, ganciclovir,
idoxuridine, amantadine, zanamivir, adefovir, interferons, lamivudine, zidovudine, didanosine,
stavudine, nevirapine, saquinavir, amprenavir, HIV protease inhibitors.
Unit-V
8. Chemotherapeutics agents: Antineoplastics – cylophosphamide, chlorambucil, melphalan, carmustine,
altretamine, thiotepa, dacarbazine, procarbazine, cisplatin, methotrexate, 6-mercaptopurine, capecitabine,
cytarabine, gemictabine, 5-fluorouracil, vinblastine, vincristine, paclitaxel, camptothecin, dactinomycin,
etoposide, L-asparaginase hydroxyurea, tamoxifen.
9. Diagnostic agents: Iodohippurate, diatrazoate, iopanoic acid, propylidone, rose bengal, fluorescine,
etyrapone, evans blue.
10. Immunomodulators: Cyclosporine, tacrolimus, mycophenolate mofetil, azathioprine.
1. Separation and identification of organic mixtures containing not more than two compounds.
2. Typical synthesis of drugs & drug intermediates using following types of reactions.
(i) Chlorosulphonation – saccharin & sulfa drugs
(ii) Esterification.
(iii) Amination by reduction.
(iv) N-methylation and N- alkylation.
(v) Mannich type reaction.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 22
Unit-I
1. Introduction to microbiology: History and scope, classification of microbes and their taxonomy – bacteria,
fungi, protozoa, viruses, actinomycetes, rickettsias, spirochetes.
2. Morphology, nutrition, identification, cultivation and isolation of: Bacteria, fungi, protozoa and viruses.
Growth of microorganisms in culture: batch, continuous and synchronous cultures.
3. Control of microbes by physical and chemical methods, evolution of anti-microbial chemical agents,
sterilization, different methods, validation of sterilization processes, sterility testing of pharmaceutical
products.
Unit-II
4. Bacterial genetics: Introduction, basic principles of molecular biology, extra chromosomal genetic elements,
genotypic and phenotypic variations, mutation, transmission of genetic, material, genetic mechanisms of
drug resistance in bacteria, transposable genetic elements and bacterial genetics applications.
5. Enzyme immobilization: Techniques of immobilization, and their applications in the industry, dynamics of
enzymatic activity, factors affecting enzyme kinetics, study of enzymes such as hyaluronidase, penicillinase,
streptokinase, streptodornase, amylases and proteases, immobilization of bacteria and plant cells.
Unit-III
6. Immunology and immunological preparations: Host-microbe interactions, the process of infection, natural
resistance and nonspecific defense mechanisms, basic and theoretical aspects of immune response.
Manufacturing and quality control of immunological products- Introduction, vaccines, in-vivo diagnostics,
immune sera, human immunoglobuline including important bacterial and viral vaccines (highlights on its
source material, processing, potency assay and safety tests).
7. Production & applications of Monoclonal antibodies.
Unit-IV
8. Fermentation Technology: Introduction, Fermenter: its design, control of different parameters, downstream
process, production of lactic acid, alcohol, penicillin and vitamin B12.
Unit-V
9. Pharmaceutical biotechnology:
Nucleic acids, the genetic code and protein synthesis: (a) Synthesis of DNA-polymerization of
nucleotides into DNA – Basic chemical structure, replication and its role in protein synthesis. (b) Synthesis of
proteins – the three roles of RNA in Translation, (mRNA, tRNA and rRNA).Genetic engineering and its
application in pharmaceutical biotechnology. Recombination DNA techniques.
Unit-I
1. Aseptic technique:
Sources of contamination and methods of prevention, design of aseptic area, laminar flow bench services
and maintenance.
Sterility testing of pharmaceuticals.
2. Parenteral products: Preformulation factors, routes of administration, WFI, pyrogenicity, non-aqueous
vehicles, isotonicity and methods of its adjustment.
Formulation details, containers and closures and selection.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 23
Prefilling treatment, washing of containers and closures, preparation of solutions and suspensions, filling and
closing of ampoules, vials, infusion fluids, lyophillization and preparation of sterile powders, equipment for
large-scale manufacture and evaluation of parenteral products.
Unit-II
3. Tablets: Formulation of different types of tablets, granulation technology on large-scale by various
techniques, physics of tablet making, theory of compression, heckle plot, different types of tablet
compression machinery and equipments employed, evaluation of tablets.
Coating of tablets: Types of coating, film forming materials, formulation of coating solution, equipments for
coating, coating process, evaluation of coated tablets.
Unit-III
4. Capsules: Advantages and disadvantages of capsule dosage form, material for production of hard gelatin
capsules, size of capsules, method of capsule filling, soft gelatin capsule, capsule shell and capsule
contents, importance of base adsorption and minim/gm factors in soft capsules, quality control, stability
testing and storage of capsule dosage forms.
5. Microencapsulation: Types of microcapsules, importance of microencapsulation in Pharmacy,
microencapsulation by phase separation, coacervation, multi orifice, spray dying, spray congealing,
polymerization, complex emulsion, air suspension technique, coating pan and other technique, evaluation of
microcapsules.
Unit-IV
6. Surgical products: Definition, primary wound dressings, absorbents, surgical cotton, surgical gauzes, etc.,
bandages, adhesive tapes, protective cellulosic haemostatics, official dressings, absorbable and
nonabsorbable sutures, ligatures & catgut. Medical prosthetics and organ replacement materials.
Unit-V
7. Packaging of pharmaceutical products: Packaging components, types, specifications and methods of
evaluation, stability aspects of packaging. Packaging equipments, factors influencing choice of containers,
legal and other official requirements for containers, package testing.
HOSPITAL PHARMACY
Unit-I
1. Organization and Structure: Organization of a hospital, organization & personnel of hospital pharmacy,
responsibilities of a hospital pharmacist, pharmacy procedural manual, Budget preparation and
Implementation, Pharmacy and Therapeutic Committee, Hospital Formulary and its contents, preparation
and revision of hospital formulary.
2. Drugs Store Management and Inventory Control:
(a) Organization of drugs store, Types of materials stocked, storage conditions
(b) Purchase and inventory control principles, purchase procedures, purchase order, procurement and
stocking.
(c) Quality control of drugs in hospitals.
Unit-II
3. Drug distribution Systems in Hospitals:
a) Dispensing of drugs to out-patients.
b) Dispensing of drugs to in-patients.
c) Dispensing of controlled drugs.
d) Pre-packaging and labeling.
e) Drug charges and charging policy.
f) Central Sterile Supply Unit and their Management.
4. Surgical supplies and health accessories
Unit-III
5. Nuclear Pharmacy: Introduction to Radio-pharmaceuticals, radio-active half life, Units of radio-activity
Production of radio-pharmaceuticals, methods of isotopic tagging, preparation of radio-isotopes in laboratory
using radiation dosimetry, radio-isotope generators, Permissible radiation dose level, Radiation hazards and
their prevention, specifications for radio-active laboratory.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 24
COMMUNITY PHARMACY
Unit-IV
6. Retail and whole sale drugs store: Organization and structure of retail and whole sale drug store, types of
drug stores and design, maintenance of drug store, dispensing of proprietary products, maintenance of
records of retail and wholesale.
7. Records and Reports: Prescription filling, drug profile, patient medication profile, annual report.
Unit-V
8. Patient counseling and Patient Compliance: Role of pharmacist in community health care and education.
9. Drugs Information Services: Sources of Information on drugs, disease, treatment schedules, procurement
of information, computerized services (e.g. MEDLINE, MEDLAR etc.), retrieval of information, medication
error, safe use of medicine, drug Information center, pharmacist as a information specialist.
Unit-I
1. Drugs acting on Autonomic nervous system: General consideration of ANS, Neurotransmitters,
cholinoreceptors, Cholinergic and Anticholinergic drugs, Neuromuscular blockers. Adrenoceptors,
Adrenergic drugs and adrenergic blockers. Drugs acting on autonomic ganglion.
Unit-II
2. Cardiovascular system:
a. Cardiac glycosides and drugs for congestive heart failure.
b. Antihypertensive drug.
c. Antianginal and vasodilator drugs, including calcium channel blockers.
d. Antiarrhythmic drug.
e. Antihyperlipedemic drug.
f. Drugs used in the therapy of shock.
Unit-III
3. Haemopoetic system:
a. Hematinics.
b. Anticoagulants, vitamin K and haemostatic agent.
c. Fibrinolytic and anti platelet drugs.
d. Blood and plasma volume expanders.
4. Urinary system:
a. Water, electrolytes and acid-base balance of body.
b. Diuretics and Antidiuretics
Unit-IV
5. Respiratory system:
a. Anti asthmatic drugs
a. Antitussives, Mucolytics and expectorants, respiratory stimulants.
6. Gastrointestinal Tract:
a. Antacids and other anti ulcer drugs.
b. Laxatives and Antidiarrhoeal drugs.
c. Appetite stimulants and suppressants.
d. Emetics, anti emetics and prokinetic drugs.
e. Carminative, digestants, enzymes and mucolytics.
Unit-V
7. Pathophysiology of following diseases: Hypertension, angina, congestive heart failure, atherosclerosis,
myocardial infarction, diabetes, peptic ulcer, asthma, ulcerative colitis, hepatic disorders, acute and chronic
renal failure, tuberculosis, urinary tract infections, sexually transmitted diseases, anemias and common types
of neoplasms. (wherever applicable the molecular basis should be discussed).
Bioassay: Principle and methods of bioassay. Some official bioassay of important drugs.
Unit-I
Systematic study of biological source, cultivation, collection, processing, of the following:
1. Resins: Study of drugs containing resins and resin combination like colophony, podophyllum, jalap,
cannabis, capsicum, myrrh, asafoetida, balsam of tolu, balsam of peru, benzoin, turmeric, ginger.
Tannins: Study of tannins and tannin containing drugs like gambir, black catechu, gall and myrobalan.
2. Volatile oils: General methods of obtaining volatile oils from plants, study of volatile oils of mentha,
coriander, cinnamon, cassia, lemon peel, orange peel, lemon grass, citronella, caraway, dill, spearmint,
clove, fennel, nutmeg, eucalyptus, chenopodium, cardamom, valerian, musk, palmarosa, gaultheria, sandal
wood.
Unit-II
3. Phytochemical Screening:
(a) Preparation of extracts.
(b) Screening of alkaloids, saponins, cardenolides and bufadienolides, flavonoids and leucoanthocyanidins,
tannins and polyphenols, anthraquinones, cynogenetic glycosides, amino acids in plant extracts.
4. Fibers: Study of fibres used in pharmacy such as cotton, silk, wool, nylon, glass-wool, polyester and
asbestos. Pharmaceutical aids: Study of pharmaceutical aids like talc, diatomite, kaolin, bentonite, gelatin
and natural colors.
Unit-III
5. Study of the biological sources, cultivation, collection, commercial varieties, chemical constituents, substitutes,
adulterants, uses, diagnostic macroscopic and microscopic features and specific chemical tests of following
groups of drugs containing glycosides:
(a) Saponins: Liquorice, ginseng, dioscorea,sarsaparilla, and senega.
(b) Cardioactive sterols: Digitalis, squill, strophanthus and thevetia.
(c) Anthraquinone cathartics: Aloe, senna, rhubarb and cascara.
(d) Others: Psoralea, ammi majus, ammi visnaga, gentian, saffron, chirata, quassia.
Unit-IV
6. Studies of traditional drugs, common vernacular names, botanical sources, morphology, and chemical nature
of chief constituents, pharmacology, categories and common uses and marketed formulation of following
indigenous drugs:
Amla, kantkari, satavari, tylophora, bhilawa, kalijiri, bach, rasna, punarnava, chitrak, apamarg,gokhru,
shankhapushpi, brahmi, adusa, arjuna,ashoka, methi, lahsun, palash, guggal, gymnema, shilajit,
nagarmotha and neem.
Unit-V
7. The holistic concept of drug administration in traditional systems of medicine. Introduction to ayurvedic
preparations like arishtas, asvas, gutikas, tailas, churnas, lehyas and bhasmas.
Unit-I
1. Chromatography: Theoretical consideration, application in drug analysis and quality control of the following
analytical techniques: column chromatography, GC, HPLC.
Unit-II
2. Theoretical consideration and application in drug analysis and quality control of the following analytical
techniques: TLC, HPTLC, paper chromatography.
Unit-III
The theoretical aspects, basic instruments, interpretation of spectra (for UV, IR, NMR, and mass spectroscopy),
and applications of the following analytical techniques should be discussed:
3. Absorption spectroscopy:
I. Ultraviolet and visible spectrophotometery
II. Infrared spectroscopy
III. Atomic absorption spectroscopy.
13
4. Nuclear magnetic resonance spectroscopy including C-NMR
Unit-IV
5. Mass spectroscopy
6. Emission spectroscopy
I. Flame photometry
II. Fluorimetry
III. X-ray diffraction
Unit-V
7. Quality assurance:
I. GLP, ISO 9000, TQM, quality review and quality documentation.
II. Regulatory control, regulatory drug analysis and interpretation of analytical data.
III. Validation, quality audit, quality of equipment, validation of equipment and validation of analytical
procedures.
Unit-I
1. Principles of drug design: QSAR methods, quantum, mechanics, computer aided drug design (CADD) and
molecular modeling.
The following topics shall cover classification, nomenclature, S.A.R., synthesis, physicochemical
properties, metabolism and therapeutic uses of drugs mentioned under each category. (Biochemical
approaches in drug design wherever applicable should be discussed. A brief introduction of latest drugs
under each category shall also be discussed).
Unit-II
2. Drugs acting on automonic nervous system:
(i) Cholinergic and anticholinesterases: Acetylcholine, methacholine, carbachol, bethanechol,
pilocarpine, muscarine, edrophonium, physostigmine, neostigmine, rivastigmine, parathion, diazinon,
malathion.
(ii) Antichlolinergics: Atropine, scopolamine, pirenzepine, tolterodine.
(iii) Adrenergics: Epinephrine, nor-epinephrine, salbutamol, dopamine, dobutamine, terbutaline,
tyramine, albuterol, amphetamine, ephedrine, isoprenaline, nephazoline, oxymetazoline.
(iv) Agents acting at the neuromuscular junction and autonomic ganglia: Atracurium, tubocurarine,
decamethonium, succinylcholine, nicotine, hexamethonium, mecamylamine.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 27
Unit-III
4. Drugs acting on central nervous system:
(i) General anaesthetics: Isoflurane, sevoflurane, nitrous oxide, thiopental, ketamine, etomidate,
propofol.
(ii) Sedative and hypnotics: Alprazolam, chlordiazepoxide, clonazepam, diazepam, lorazepam,
nitrazepam, oxazepam, midazolam, zolpidem, phenobarbitone, pentobarbitone, meprobamate.
(iii) Antidepressants: Amitriptyline, doxepine, desipramine, citalopram, fluoxetine, sertraline, bupropion,
phenelzine, pargyline, meclobamide.
(iv) Antipsychotics: Chloropromazine, fluphenazine, trifluoperazine, thiothixene, clozapine, haloperidol,
loxapine, pimozide, ziprasidone, risperidone.
(v) Antiepileptics: Phenytoin, carbamazepine, ethosuximide, lamotrigine, valproic acid, gabapentin,
lamotrigine, zonisamide.
(vi) Antiparkinsonian drugs: Levodopa, carbidopa, bromocriptine, pergolide, trihexyphenidyl.
(vii) Opioid analgesics: Morphine, heroin, codeine, naloxone, nalorphine, meperdine, fentanyl,
methadone, dextro-propoxyphene, dextromethorphan, pentazocine.
(viii) Non-steroidal anti-inflammatory drugs: Aspirin, paracetamol, indomethacin, mefenamic acid,
tolmetin, diclofenac, ibuprofen, ketoprofen, phenylbutazone, analgin, piroxicam, nimesulide,
valdecoxib, etoricoxib, acelofenac.
(ix) CNS stimulants: Strychnine, picrotoxin, nikethamide, bemegride, caffeine, theophyline.
Unit-IV
5. Drugs acting on cardiovascular system:
(i) Antihypertensive agents: Reserpine, guanethidine, diazoxide, hydralazine, minoxidil, methyldopa,
prazosin, clonidine, pargyline, propranolol, phenoxybenzamine, atenolol, captopril, enlapril, lisinopril,
nifedipine, amlodipine, diltiazem, verapamil.
(ii) Antiarrythmic agents: Quinidine, di-isopyramide, procainamide, moxilitene, amoidarone, flecainide.
(iii) Antianginal agents: Glyceryltrinitrate, amylnitrate, isosorbide dinitrite.
(iv) Antiatherosclerotic agents: Atorvastatin, simvastatin, colestipol, clofibrate, gemfibrozil.
6. Drugs acting on kidney: Diuretics – Mannitol, furesamide, bumetanide, ethacrynic acid, chlorthiazide,
hydrochlorthiazide, chlorthalidone, acetazolamide, amiloride, triamterene, spironlactone.
Unit-V
7. Hormones and related drugs:
(i) Hypoglycaemic agents: Insulin, tolbutamide, chlorpropamide, phenformin, metformin, glyburide,
glipizide, repaglinide, pioglitazone.
(ii) Thyroid hormone and antithyroid drugs: Thyroxine, propylthiouracil, methimazole, carbimazole.
8. Autocoids and related drugs:
(i) Antihistaminics: Diphenhydramine, dimenhydrinate, doxylamine, mepyramine, tripellanamine,
pheniramine, chlorpheniramine, dexachlorpheniramine, triprolidine, promethazine, methdilazine,
antazoline, cyprohepatadine, azatidine, astemazole, cetrizine, fexofenadine.
(ii) Eicosinoids: Prostaglandins: misoprostol, rioprostil, dinoprostone, carboprost tromethamine,
alprostadil, metenprost.
9. Drugs acting on gastrointestinal tract:
(i) Antiulcer drugs: Cimetidine, ranitidine, famotidine, loratidine, roxatidine, omeprazole, lansoprazole,
pantoprozole, rabeprazole.
(ii) Antidiarrhoeal drugs: Loperamide, diphenoxylate, racecadotril.
(iii) Emetics and antiemetics: Emetine, apomorphine, ondansetron, metoclopramide, cyclizine,
promethazine, domperidone.
10. Combinatorial chemistry: Introduction, supports, linkers, solution-phase combinatorial chemistry, pooling
strategies, detection, purification, analysis, high-throughput screening, chemical diversity and library design.
Typical synthesis of drugs & drug intermediates by use of the following types of reactions and establishing
pharmacopoeial standards of the drugs synthesized.
(i) Benzoin condensation
(ii) Benzilic acid arearrangement
(iii) Friedel Crats alkylation and acylation
(iv) Hoffmann – Bromamide reaction
(v) Perkin condensation
(vi) Grignard reaction
(vii) Claisen condensation
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 28
Unit-I
1. Preformulation studies: Study of physical properties of drugs like physical form, particle size, shape,
density, wetting and dielectric constant, solubility, dissolution and organoleptic properties and their effect on
formulation, stability and bioavailability.
Study of chemical properties of drugs like hydrolysis, oxidation, reduction, racemization, polymerization etc.
and their influence on formulation and stability of products.
Study of pro-drugs in solving problems related to stability, bioavailability and elegance of formulations.
Unit-II
2. Design, development and process validation methods for pharmaceutical operations involved in the
production of pharmaceutical products with special reference to tablets and solutions.
Stabilization & stability testing protocol for various pharmaceutical products with special reference to tablets
and solutions.
Unit-III
Unit-IV
5. Cosmeticology and cosmetic preparation: Fundamentals of cosmetic science, structure and function of
skin and hair. Formulation preparation and packaging of cosmetic for skin, hair, dentifrices and manicure
preparation lipsticks, eyelashes, baby care products etc.
Unit-V
6. Novel Drug Delivery Systems: Basic concept, merits and demerits, design, development, production &
evaluation of following delivery systems- sustained & controlled release dosage forms (with special reference
to tablets, capsules and oral liquids), nanoparticles, liposomes, resealed erythrocytes, microspheres,
microcapsules, fast dissolving dosage forms.
1. Preformulation studies including drug-excipient compatibility studies, effect of stabilizers, preservatives etc.
in dosage form design.
2. Experiments demonstrating improvement in bioavailability through prodrug concept.
3. Stability evaluation of various dosage forms and their expiration dating.
4. Dissolution testing and data evaluation for oral solid dosage forms.
5. In-vivo bioavailability evaluation from plasma drug concentration and urinary excretion curves.
6. Design, development and evaluation of controlled release formulation.
7. Formulation of various types of cosmetics for skin, hair, dentifrices and manicure preparations.
BIOPHARMACEUTICS
Unit-I
1. Introduction to Biopharmaceutics
2. Delivery of drugs: Routes of administration, transport of drugs across biological barrier (passive diffusion,
active transport, facilated diffusion, pinocytosis, etc.).
3. Absorption of drugs: Factors influencing absorption such as physicochemical factors, biopharmaceutical
factors, manufacturing processing factors, pharmacokinetic factors
4. Distribution of Drugs: Tissue permeability, physiological barriers, volume of distribution.
Unit-II
5. Termination of drug action: Biotransformation of drugs, protein binding of drugs, excretion of drugs,
Concept of clearance – Renal clearance, mechanism of renal clearance, clearance ratio, determination of
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 29
renal clearance, Non-renal routes of drug elimination (Extraction ratio, hepatic clearance, biliary excretion,
extrahepatic circulation).
6. Bioavailability and bioequivalence: Measure of bioavailability, Cmax, tmax, and area under the curve
(AUC), Design of single dose bio-equivalence study and relevant statistics, Review of regulatory
requirements for conduction of bioequivalent studies
PHARMACOKINETICS
Unit-III
7. Introduction to Pharmacokinetics: Rate, Rate constants and order of reactions (Zero order and first order
kinetics)
8. Concept of compartment modeling: Introduction, compartment models- Intravenous administration,
Extravascular administration
Unit-IV
9. Non-linear Pharmacokinetics with special reference to one compartment model after I V drug
administration, Michaeles Menten Equation, determination of non - linearity (Saturation mechanism).
MISCELLANEOUS
10. In vivo-In vitro Correlation
Unit-V
11. Mean residence time concept
12. Statistical moments analysis
13. Multiple dosing and steady state levels and their relationship with single dose administration.
14. International regulation regarding bioavailability and bioequivalence studies
1. Experiments designed for the estimation of various pharmacokinetic parameters with given data.
2. Analysis of biological specifications for drug content and estimation of the pharmacokinetics parameters.
3. In vitro evaluation of different dosage forms for drug release.
4. Absorption studies in- vitro and in -situ.
5. Statistical treatment of pharmaceutical data.
6. Preparation of surgical dressings, sterile infusions, adhesive tapes and bandages.
7. Experiments based on sterilization of various types of materials like surgical dressings, surgical equipments,
glasswares, gowns, headgears, mask, gloves etc. used in Hospitals.
8. Evaluation of cotton, bandages, dressings, tapes and infusion.
9. Evaluation of containers and closures for parenteral use.
10. Preparation of haemostat.
11. Practicals designed on the use of computers in Drug Information Center, prescription filling, documentation
of information on drug interaction.
Unit-I
1. Chemotherapy: General principles of chemotherapy
Antimicrobial drugs: Sulfonamides and cotrimoxazole, beta-lactam antibiotics, Cephalosporins, tetracyclines
and chloromphenicol (broad spectrum antibiotics), quinolones, aminoglycoside antibiotics, macrolides and
other antibacterial.
Unit-II
2. Antifungal, Antiviral, Antimalarial, Antiamoebic and other antiprotozoal drugs, anthelmintics.
Unit-III
3. Chemotherapy of urinary tract infections, cancer, tuberculosis, leprosy and sexually transmitted diseases
and immunosuppressive agents.
4. Complete pharmacology of following Local anti infective agents, sera, vaccines, diagnostic agents and
vitamins. Gene-therapy.
Unit-IV
5. Clinical Pharmacy:
a. Basic concepts of pharmacotherapy
b. Clinical pharmacokinetics and individualization of drug therapy
c. Drug delivery systems, their biopharmaceutical and therapeutic considerations.
d. Use of drugs in infants and in elderly patients
e. Use of drugs during pregnancy and lactation
f. Therapeutic Drug monitoring
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 30
Unit-V
6. a. Principles of Toxicology: Definition of poison, general principles of treatment of poisoning with particular
reference to barbiurates, opioids, salicylates, organ- opnosphorous and atropine poisoning.
b. Heavy metals and heavy metal antagonists.
Unit-I
1. Systematic study of biological source, cultivation, collection, processing, commercial varieties, chemical
constituents, substitutes, adulterants, uses, diagnostic macroscopic and microscopic features and specific
chemical tests of following alkaloid-containing drugs:
(a) Pyridine-piperidine: Tobacco, areca and lobelia.
(b) Tropane: Belladonna, hyoscyamus, datura, duboisia, coca and withania.
(c) Quinoline and isoquinoline: Cinchona, ipecac, opium.
(d) Indole: Ergot, rauwolfia, catharanthus, nux-vomica and physostigma.
(e) Imidazole: Pilocarpus
(f) Steroidal: Veratrum and kurchi
(g) Alkaloidal amine: Ephedra and colchicum.
(h) Glycoalkaloid: Solanum.
(i) Purines: Coffee, tea and cola.
Unit-II
2. Role of medicinal and aromatic plants in national economy. Biological sources, preparation, identification
tests and uses of the following enzymes: Diastase, papain, pepsin, trypsin and pancreatin.
3. General techniques of biosynthetic studies and basic metabolic pathways. Brief introduction to biogenesis of
secondary metabolites of pharmaceutical importance. Plant bitters and sweeteners.
Introduction, classification and study of different chromatographic methods and their applications in
evaluation of herbal drugs.
Unit-III
4. World-wide trade in medicinal plants and derived products with special reference to diosgenin (disocorea),
taxol (Taxus sps) digitalis, tropane alkaloid containing Plants, Papain, Cinchona, Ipecac,Liquorice, Ginger,
Aloe,Valerian, Rauwolfia, and Plants containing laxatives. . A brief account of plant based industries and
institutions involved in work on medicinal and aromatic plants in India. Utilization and production of
phytoconstituents such as quinine, calcium sennosides, podophyllotoxin, diosgenin, solasodine, and tropane
alkaloids.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 31
Unit-IV
5. Utilization of aromatic plants and derived products with special reference to sandalwood oil, mentha oil,
lemon grass oil, vetiver oil, geranium oil and eucalyptus oil. Historical development of plant tissue culture,
types of cultures, nutritional requirements, growth and their maintenance. Application of plant tissue culture
in pharmacognosy.
Unit-V
6. Chemotaxonomy of medicinal plants. Marine pharmacognosy, novel medicinal agents from marine sources.
7. Natural allergens and photosensitizing agents and fungal toxins. Herbs as health foods. Herbal cosmetics.
Unit-I
1. Management: Meaning, Evolution - Scientific, administrative and human relation approach. Process of
management: Planning, organizing, staffing, directing, coordinating and controlling – a preliminary idea of
their concepts, processes and techniques. Functional areas of management: Production management,
marketing management, personnel management, financial management - their meaning and functions.
Entrepreneurship development.
2. Economics: Principles of economics with special reference to the laws of demand and supply, demand
schedule, demand curves, labour welfare.
Unit-II
3. Production management: Nature and scope of production and operations management, strategic
operations management A brief exposure of different aspects of production management- visible and
invisible inputs, methodology of activities, performance evaluation techniques, process flow, process know
how and maintenance management. Production planning and control, production processes - mass, job and
project; plant location and lay out; work study (preliminary idea only). manufacturing and services operations,
product and process design, process planning, plant utilities, production technology, materials handling,
factory building, shop floor planning. Materials management, purchasing, purchasing policies, materials
storing and inventory management.
Unit-III
4. Market research: Marketing research and information system Market demands- major concepts in the
demand measurement, estimating current demands, geo-demographic analysis, estimating industry sales,
market share and future demand.
5. Pharmaceutical marketing: Evolution of modern concept; market segmentation; concept of marketing mix;
product planning; pricing, promotion; channels of distribution developing the marketing mix – product and
service strategies, new product development and product life cycle strategies. Field sales management,
sales organization, training of sales personnel, compensation of sales force, field sales planning control and
risk, sales forecasting, sales budget and budgetary control, sales literature, catalogue and price list.
Concepts and nature of advertising, advertising and marketing, effects of advertising, social effects of
advertising, ethics, advertising process, media selection, massages, planning and budget.
Unit-IV
6. Personnel management: Marketing – objective an scope, developing marketing opportunities and
strategies Recruitment and selection of employees, orientation and training, evaluation and compensation,
retrenchment, lay off and discharge. General principles of insurance and inland and foreign trade, procedure
of exporting and importing goods.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 32
Unit-V
7. Industrial psychology: Transactional analysis - Meaning, ego status, types of transactions and life
positions – a preliminary idea. Organization development- (preliminary idea). Motivation – Maslow’s theory,
approaches and styles of leadership (preliminary idea).
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 33
Human Anatomy, Physiology and Health Education (B.Ph. 111T & B.Ph.112P)
1. Derashari and Gandhi; Human Anatomy and physiology; B.S. Shah Prakashan.
2. C. Chatterjee; Human Physiology; Medical Alied Agency, Calcutta.
3. Goyal, Bhatt and Kumar; Basics of Health Education and Community Pharmacy; B.S. Shah Prakashan.
4. Warwick & Williman Longman; Gray's Anatomy.
5. Sahana's Text Book of Anatomy.
6. Willium and Wilkins, Baltimore Best and Taylor's Physiological Basis of Medical Practice.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 34
Pharmaceutical Engineering, Unit Operations and Engineering Drawing (B.Ph. 207T & B.Ph. 208P)
1. Badger W.L. and Banchero J.T.; Introduction to chemical engineering, McGraw Hill International Book Co.,
London.
2. Parry R. H. & Chilton C. H., Chemical Engineers Handbook, McGraw Kogakusha Ltd.
3. Lachmen L., Lieberman H. A., The Theory and Practice of Industrial Pharmacy, Lee & Febiger, Philadelphia.
4. Carter S.J., Cooper and Gunn’s Tutorial Pharmacy, CBS Publishers, Delhi
5. Brown C.G., Unit Operations (Indian Ed.) Asia Publishing House, Bombay.
6. MaCabe W.L., Smith J.L., Unit Operations of Chemical Engineering, McGraw Hill International Book Co.,
London.
7. Bhatt, N.D., Machine Drawing.
8. J.G.Hardman, L.E., Limbird, P.B.Molinoss, R.W.Rudden & A. G. Gil, Goodman & Gilmans, The
Pharmacological basis of Therapeutics, Pergamon Press.
9. Tripathi, K.D., Essentials of Medical Pharmacology, Jaypee Brothers, New Delhi
10. Herindal E. T. & Hirschman J.L., Willams and Wilkins, Clinical Pharmacy and Therapeutics.
11. Katzung B. G., Basic and Clinical Pharmacology, Prentice Hall International.
12. Lawrence D.R. and Bennet P. N., Clinical Pharmacology; Churchill Livingstone.
13. Myeek M. J., Gertner S. B. & Perper M. M., Pharmacology Lippincatt’s Illustrated Reviews, Lippinocott
Company, Philadelphia.
14. Panl L., Chapmom and Hall, Principles of Pharmacology.
15. Dipiro, J.L.Elseuier, A Pathophysiological Approach: Phermacotherpay.
16. Rang M.P., Dale M.M., Riter J.M.,Pharmacology, Churchill Liningstone.
17. Robbinson S. L. and Kumar V.; Basic Pathology, W. B. Saunders Co.
18. Theoharides T. C., Pharmacology; Little Brown & Co.
19. B. C. Bose, Pharmacology
20. James crossland, Levi’s Pharmacology
21. Ghosh, Pharmacology materia medical and therapeutics.
22. Sharma V.N., Essentials of Pharmacology.
Dosage Form Design and Cosmeticology (B.Ph. 405T & B.Ph. 406P)
1. Wilson & Gisvold’s Textbook of Organic Medicinal & Pharmaceutical chemistry, J.B.Lippincott Co.
2. Foye W.O., Principles of Medicinal chemistry.
3. Wolff M.E., Burger’s medicinal chemistry, John Wiley & Sons.
4. Remingtons Pharmaceutical sciences.
5. Vogel’s Textbook of practical organic chemistry, ELBS.
6. Pharmacopoeia of India
7. British Pharmacopoeia
8. United States Pharmacopoeia
9. Mann & Saunders – Practical organic chemistry.
10. Atherden L. M., Bentley and Driver’s Text book of Pharmaceutical Chemistry, Oxford University Press,
London.
11. Chatten L. G. A Textbook of Pharmaceutical Chemistry, Vol I and II, Marcel Dekker, New York.
12. Exploring QSAR Vol; I Fundamentals and Applications in Vhemistry and Biology by C Hansh and A Leo Vol.
II: Hydrophobic, Electronic and Steric constants by C. Hansh, A Leo and D. Hockman ACS Book Catalog.
13. Hansh C., Comprehensive Medicinal Chenistry, Vol. IV, Quantitative Drug Design, Pergamon Press, Oxford.
14. Landu B. N. Mandel H. G. and way E. L., Fundamentals of Drugs Metabolism and Disposition, William and
Welkind Co. 428 E., Preston Street, Baltimore.
15. Martine Y. C., Quantitative Drug Design – A Critical Introduction (Medicinal Research Monograph, Vol. 8)
Marcel Dekkers, inc. New York.
16. Nogrady T., Medicinal Chemistry – A Biochemical Approach Oxford University Press, New York, Oxford.
17. Pop and Perruns, Computer Aided Drug Design, Academic Press, NY.
18. Reynolds J. E. F., Martindale, The Extra Pharmacopoeia, The Pharmaceutical Press, London
19. Jellinek J. S., Formulation and Function of Cosmetics, John Wiley and sons, NY.
20. Mithal, Saha Hand book of cosmetics.
Syllabus: Bachelor of Pharmacy Rajasthan University of Health Sciences, Jaipur 40
Pharmacology – III and Clinical Pharmacy (B.Ph. 409T & B.Ph. 410P)
1. Rowland M. and Tozer T.N.; Clinical Pharma cokinetics, Lea & Feblger, NY.
2. Welling Peter G. and Tse Francis L.S.; Pharmacokinetics, Marcel Decker Inc. N.Y.
3. Winter M.E.; Basic Clinical Pharmacokinetics, Applied Therapeutics, Ine San Francisco.
4. Wagner J.G.; Pharmacokinetics for Pharmaceutical Scientist; Technomic Publishing A. G. Basel,
Switzerland.
5. Wagner J.G.; Fundamentals of Pharmacokinetics; Drug intelligence publication, Hamilton.
6. Ritschel W. A.; Handbook of Basic Pharmacokinetics; Drug Intelligence Publication, Hamilton.
7. Motari R.E.; Biopharmaceutics and Pharmacokinetics an Introduction; Marcel Decker Inc. NY.
8. Gibaldi M.; Biopharmaceutics and Clinical Pharmacokinetics; Philadelphia.
9. Gibaldi M. and Perrier D.; Pharmacokinetics; Marcel Decker Inc. NY.
10. Pecile A. and Resigno A.; Pharmacokinetics; Plenum Press NY.