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Ofcial Journal of the

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VOL 62, NO 6, DECEMBER 2013 xx Announcement xxi This Month in AJKD xxv Quiz Page: Hypoplastic Nails, Bowed Elbows, and Nephrotic Syndrome
Swasti Chaturvedi, Anna Pulimodd, and Indira Agarwal

EDITORIALS 1023 Variation in Performance of Kidney Injury Biomarkers Due to Cause of Acute Kidney Injury
Chirag R. Parikh and Gang Han

Related Article, p. 1058 1027 Shenqi Particle: A Novel Therapy for Idiopathic Membranous Nephropathy
Madhav C. Menon, Peter Y. Chuang, and John Cijiang He

Related Article, p. 1068 1030 Have We Reached the Limit of Mortality Benet With Our Approach to Renal Replacement Therapy in Acute Kidney Injury?
Sarah Faubel

Related Article, p. 1116 1034 Milestones for Nephrology Training Programs: A Modest Proposal
Christina M. Yuan, Robert Nee, Kevin C. Abbott, and James D. Oliver III

IN THE LITERATURE 1039 Kidney Stones and the Risk of Coronary Heart Disease
David S. Goldfarb

Cover Illustration: See Troxell et al, p. 1193


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PERSPECTIVE 1042 Understanding Washington: A Nephrologists Perspective From Inside the Beltway
Robert J. Rubin

SPECIAL REPORT 1046 Patient-Reported Outcomes in Clinical Trials of CKD-Related Therapies: Report of a Symposium Sponsored by the National Kidney Foundation and the US Food and Drug Administration
Ronald D. Perrone, Stephen Joel Coons, Kerri Cavanaugh, Fred Finkelstein, and Klemens B. Meyer

ORIGINAL INVESTIGATIONS Pathogenesis and Treatment of Kidney Disease 1058 Urinary Interleukin 18 for Detection of Acute Kidney Injury: A Meta-analysis
Yawei Liu, Wenyuan Guo, Jiayou Zhang, Chenggang Xu, Shengqiang Yu, Zhiguo Mao, Jun Wu, Chaoyang Ye, Changlin Mei, and Bing Dai

Editorial, p. 1023 1068 Efcacy and Safety of Traditional Chinese Medicine (Shenqi Particle) for Patients With Idiopathic Membranous Nephropathy: A Multicenter Randomized Controlled Clinical Trial
Yiping Chen, Yueyi Deng, Zhaohui Ni, Nan Chen, Xiangmei Chen, Wei Shi, Yongli Zhan, Fahuan Yuan, Wei Deng, and Yifei Zhong

Editorial, p. 1027 1077 Acute Kidney Injury and Death Associated With Renin Angiotensin System Blockade in Cardiothoracic Surgery: A Meta-analysis of Observational Studies
Rabi Yacoub, Nilang Patel, James W. Lohr, Srini Rajagopalan, Nader Nader, and Pradeep Arora

1087 Association of Income Level With Kidney Disease Severity and Progression Among Children and Adolescents With CKD: A Report From the Chronic Kidney Disease in Children (CKiD) Study
Guillermo Hidalgo, Derek K. Ng, Marva Moxey-Mims, Maria Lourdes Minnick, Tom Blydt-Hansen, Bradley A. Warady, and Susan L. Furth

1095 Day-to-Day Variability in Spot Urine Albumin-Creatinine Ratio


Chetana N. Naresh, Andrew Hayen, Alexander Weening, Jonathan C. Craig, and Steven J. Chadban

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1102 Comparison of Associations of Urine Protein-Creatinine Ratio Versus Albumin-Creatinine Ratio With Complications of CKD: A Cross-sectional Analysis
Herrick Fisher, Chi-yuan Hsu, Eric Vittinghoff, Feng Lin, and Nisha Bansal

1109 A Comparison of the Performances of an Articial Neural Network and a Regression Model for GFR Estimation
Xun Liu, Ning-shan Li, Lin-sheng Lv, Jian-hua Huang, Hua Tang, Jin-xia Chen, Hui-juan Ma, Xiao-ming Wu, and Tan-qi Lou

Dialysis 1116 Earlier-Start Versus Usual-Start Dialysis in Patients With Community-Acquired Acute Kidney Injury: A Randomized Controlled Trial
Tukaram E. Jamale, Niwrutti K. Hase, Manjunath Kulkarni, K.J. Pradeep, Vaibhav Keskar, Sunil Jawale, and Dinesh Mahajan

Editorial, p. 1030 1122 Correlation of Pre-existing Vascular Pathology With Arteriovenous Graft Outcomes in Hemodialysis Patients
Michael Allon, Silvio Litovsky, Carlton J. Young, Mark H. Deierhoi, Jeremy Goodman, Michael Hanaway, Mark E. Lockhart, and Michelle L. Robbin

1130 Patient Care Stafng Levels and Facility Characteristics in US Hemodialysis Facilities
Laura A.G. Yoder, Wenjun Xin, Keith C. Norris, and Guofen Yan

1141 Changes in Anthropometry and Mortality in Maintenance Hemodialysis Patients in the HEMO Study
Chi-Ting Su, Jonathan Yabes, Francis Pike, Daniel E. Weiner, Srinivasan Beddhu, Jerrilynn D. Burrowes, Michael V. Rocco, and Mark L. Unruh

CASE REPORTS 1151 Acquired Hypocalciuric Hypercalcemia in a Patient With CKD


Elizabeth Kuo, E. Helen Kemp, Harpreet K. Sandhu, Edward M. Brown, Anthony P. Weetman, and Chou-Long Huang

1155 Nocturnal Home Hemodialysis for a Patient With Type 1 Hyperoxaluria


Troy J. Plumb, Melissa L. Swee, and Jennifer A. Fillaus

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1160 Pregnancy-Associated Polyuria in Familial Renal Glycosuria


Hakan R. Toka, Jun Yang, Chloe A. Zera, Jeremy S. Dufeld, Martin R. Pollak, and David B. Mount

NARRATIVE REVIEW 1165 Population Ancestry and Genetic Risk for Diabetes and Kidney, Cardiovascular, and Bone Disease: Modiable Environmental Factors May Produce the Cures
Barry I. Freedman, Jasmin Divers, and Nicholette D. Palmer

IN TRANSLATION 1176 Pathogenesis of ANCA-Associated Vasculitis: New Possibilities for Intervention


Cees G.M. Kallenberg, Coen A. Stegeman, Wayel H. Abdulahad, and Peter Heeringa

ACID-BASE AND ELECTROLYTE TEACHING CASE 1188 Trimethoprim-Associated Hyponatremia


Revekka Babayev, Soa Terner, Subani Chandra, Jai Radhakrishnan, and Sumit Mohan

KIDNEY BIOPSY TEACHING CASE 1193 Light Chain Renal Amyloidosis With Prominent Giant Cells
Megan L. Troxell, Ryan Grifths, Ian Schnadig, and Donald C. Houghton

CORE CURRICULUM IN NEPHROLOGY 1198 Kidney Disease in the Setting of Liver Failure: Core Curriculum 2013
Thomas A. Gonwa and Hani M. Wadei

DOPPS PRACTICE MONITOR UPDATE 1213 The DOPPS Practice Monitor for US Dialysis Care: Update on Trends in Anemia Management 2 Years Into the Bundle
Douglas S. Fuller, Ronald L. Pisoni, Brian A. Bieber, Friedrich K. Port, and Bruce M. Robinson

1217 Commentary on The DOPPS Practice Monitor for US Dialysis Care: Update on Trends in Anemia Management 2 Years Into the Bundle: Iron(y) Abounds 2 Years Later
Daniel E. Weiner and Wolfgang C. Winkelmayer

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CORRESPONDENCE Letters to the Editor 1221 Tuberculous Lymphadenitis in a Dialysis Patient Diagnosed by 18-Fluorodeoxyglucose Positron Emission Tomography and IFN-g Release Assay
Tsuyoshi Inoue, Masaomi Nangaku, and Fumihiko Hinoshita

1221 Bilateral Nephrectomy Signicantly Improves Health-Related Quality of Life in a Hemodialysis Patient With Autosomal Dominant Polycystic Kidney Disease
Chia-Ter Chao, Shuo-Meng Wang, and Tze-Wah Kao

1222 Hemodialysis Arteriovenous Fistula Created From the Posterior Tibial Artery and a Saphenous Vein Branch
Taiga Hara, Tadashi Sofue, and Masakazu Kohno

Research Letter 1223 AntiePhospholipase A2 Receptor Antibodies and Malignancy in Membranous Nephropathy
Sjoerd A.M.E.G. Timmermans, Rivka Ayalon, Pieter van Paassen, Laurence H. Beck Jr, Henk van Rie, Joris J.J.M. Wirtz, Gaico H. Verseput, Leon A. Frenken, David J. Salant, and Jan Willem Cohen Tervaert, on behalf of the Limburg Renal Registry

ACKNOWLEDGEMENT 1226 List of AJKD Reviewers, October 1, 2012 to September 30, 2013 NOTICES 1230 Erratum Regarding A Crystal Clear Diagnosis (Am J Kidney Dis. 2013;62:xxvi-xxix) 1230 Erratum Regarding Differences Between Ofce and 24-Hour Blood Pressure Control in Hypertensive Patients With CKD: A 5,693-Patient Cross-sectional Analysis From Spain (Am J Kidney Dis. 2013;62(2):285-294)
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