MCQ QUESTIONS

BATCH 4 (03/07) YEAR 2 SEMESTER 2 FINAL EXAM EXAM DATE : MONDAY, 25TH MAY 200
1. Koilocytes with small perinuclear halo may be due to this infection A. Candida alblicans B. Actinomyces Israeli C. Gardenerala vaginalis D. Trihcomonas vaginalis Rosette formation is typical of: A. sqamous cell carcinoma B. Adenocarcinoma C. mature metapalstic cells D. inflammed cells Aniso!aryosis denotes A. "ariation in cell si#e B. "ariation in nuclear si#e C. "ariation in nuclear si#e and shape D. "ariation in cell si#e and shape %n"asi"e squamous cell carcinoma is usually related to these strains of &'( A. &'( type 1$ ) 1* B. &'( type 1* ) 1+ C. &'( type 1+ ) 1 D. &'( type 2, ) A satisfactory 'A' smear should contain a minimum of .. clusters of well preser"ed endocer"ical cells A. 2 B. $ C. * D. +

2.

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/ne of these cells normally ha"e scanty cytoplasm A. metaplastic cells B. parabasal cells C. D. endocer"ical cells endometrial cells

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%f a 1aturation %nde2 3i"es this result: ':%:4 5 ,:2-:0-6 it is due to A. estro3en effect B. pro3esterone effect C. andro3en effect D. luteinisin3 hormone effect &4( type % normally affects the A. face and arms B. se2 or3ans C. 1outh D. internal or3ans 8he synonym for C%9 %%% is A. low 3rade intraepithelial lesion B. hi3h 3rade intraepithelial lesion C. mild dysplasia D. moderate dysplasia 8he 1aturation %nde2 of 1,,:,:, su33ests A. atrophy chan3es B. &ypertrophy C. reacti"e chan3es D. Re3eneration

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8he Bethesda scheme of report pro"ides 11. A. B. C. D. 12. descripti"e dia3nosis 'apnicolaou classification C%9 classification dysplasia classification

8he cytopatholo3ists must screen daily ... of ne3ati"e 'A' smears A. 1,: B. 1-: C. 2,: D. 2-: 8his type of cells show intra;cellular brid3es A. parabasal cells B. endocer"ical cells C. metaplastic cells D. intermediate squamous cells 'rominent nucleoli may be seen in these cells6 EXCE!T A. &isteocytes B. inflamed %ntermediate squamous cells C. endoce"ical cells D. plasma cells

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8hese cells can be seen in smears ta!en durin3 day 1;- of the menstruation cycle6 EXCE!T A. 'latelets B. endometrial cells C. pus cells D. erythrocytes Bare nuclei of this type of de3enerated cells can be confused with the tropho#oite of Trichomonas Vaginalis A. columnar cells B. enodmetrial cells C. superficial 4qaumous cells D. intermediate 4qaumous cells <nlar3ed6 hyperchromatic nuclei usually indicates A. C%9 1 B. C%9 2 C. C%9 D. inflammatory chan3es 8adpole cells are indicati"e of A. beni3n conditions B. inflammatory cells C. D. pre mali3nant cells mali3nant cells

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17.

1ycobacterium tuberculosis is cultured in A. Blood a3ar

B. C. D. 2,.

4abroud a3ar Chocolate a3ar =owenstein >ensen media

1icronucleoli are present in all these cells 6 EXCE!T A. &isteocytes B. metaplastic cells C. normal <ndocer"ical cells D. parabasal cells 8he followin3 are cellular chan3es caused by &4( infection6 EXCE!T A. Binucleation B. perinuclear halo C. hyperchromatic nuclei D. 3round 3lass appearance &yper!eratic squamous cellsnormally stain A. blue B. ?reen C. /ran3e D. 'in! @alse positi"e dia3nosis of cer"ical squamous intraepithelial lesions may be due to A. B. C. D. folic deficiency iron deficiency protein deficiency 8halassemia

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%n"asi"e 4quamous carcinoma is usually caused by this strain of &'( A. &'( type 1+ B. &'( type , C. &'( type 1 D. &'( type 8he presence of metaplastic cells means the 'A' smear ha"e been ta!en from the ... re3ion A. B. C. D. (a3inal <ctocer"i2 <ndocer"i2 <ndometrium

2-.

BATCH 5 (02/0") YEAR 2 SEMESTER 2 MIDSEMESTER EXAM EXAM DATE : THURSDAY, 3#$DECEMBER 200

Ahich is the characteretic feature of Beni3n =esion

A B C D 2

=imited proliferation. %n"ade surroundin3 tissues 1etastasi#e. Bnlimited proliferation.

.......... are used to detemine the adequacy of 'A' smear A 4quamous epithelial cells. B <ndocer"ical cells C 9eoplastic cells D <2ocer"ical cells ......... are principally composed of cells formin3 nests of sheet or rosette li!e clusters A 4quamous cell carcinoma B Adenocarcinoma C ?ranulosa cell tumors D 'apillomas

%n"asi"e carcinoma show the followin3 criteria e2cept A %rre3ular nuclear chromatin B 'resence if inflammation ) necrosis C 'rominent nucleoli D 'resence of pseudohyphae =esions showin3 little or no resemblance of the epithelium of ori3in and which is composed of small abnormal cells is A 9ormal 3rade B Abnormal 3rade C =ow 3rade D &i3h 3rade %n"asi"e cer"ical carcinoma should be confirmed by A Blood test B Biopsy C Brine test D Bltrasound .......... are enlar3ed squamous cells with hyperchromatic nuclei and a lar3e perinuclear clear halo A 1yelocytes B Koilocytes C 1onocytes D 8ar3et cells Bntreated precursor lesions usually ta!e ........... to pro3ress to in"asi"e cancer A 4e"eral days B 4e"eral wee!s C 4e"eral months D 4e"eral years Dysplasia can be subdi"ided into followin3 e2cept A Keratini#in3

B C D 1,

9on !eratini#in3 1etaplastic 9eoplastic

A sarcoma is a A Beni3n lesion B 1ali3nant lesion C 'recursor lesion D Rhabditiform lar"a 8he physiolo3ical con"ersion of columnar endocer"ical cells to flat e2ocer"ical cells is termed A 1etaplasia B Atypia C 1etastasis D 'ara!eratosis .............. are Beni3n tumors deri"ed usually from 4quamous epithelium A Adenoma B 'apilloma C 'olyp D 8eratoma 8he followin3 are cellular chan3es caused by &'( %&'%() A 9uclear mouldin3 B &yperchromatic nuclei C 'erinuclear halo D &yperse3mentation 'roliferation of cancer cell to distant or3ans is called A %n"asion B 1etaplasia C 1etastasis D Keratinisation %f a 1aturation %nde2 3i"es this result : ':%:4 5 7,:1,:,6 it is due to A <stro3en effect B Andro3en effect C 'ro3esterone effect D All =ow 3rade squamous intraepithelial lesions are associated with the followin3 e2cept A 1ild dysplasia B &yperchromatic nuclei C Koiloytes D 'seudoeosinophilia 1ost onco3enic &'( is A 8ype 1 B 8ype * C 8ype 1* D 8ype 11

11

12

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8he term aniso!aryosis refers to si3nificant "ariation in A Cell si#e B Cell shape C 9ucleoli si#e ) shape D 9uclear si#e ) shape 8he technique for inspection of "ascular chan3es on the surface of cer"i2 is called A Colposcopy B Colonoscopy C =aryn3oscopy D Bronchoscopy Ahich of the followin3 does not result from the effect of radiation A Cellular baloonin3 B 9uclear Baloonin3 C (acuolisation of Cytoplasm ) 9ucleus D Denucleation

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4mall cell carcinoma is 3raded as A Grade 1 B Grade 2 C Grade 3 D Grade 4 8he pro3nostically fa"ourable feature in sta3e 1 in"asi"e carcinoma is the presence of A =ymphocytic infilteration in stroma B 1etastasis to re3ional lymph node C %n"asion of =ymphatics D 9one 8he 9uclear enlar3ement in otherwise normally appearin3 cells is termed A Dys!aryotic B Karyome3aly C Koilocytosis D Keratosis %n a normal 'A' smear6 mature metaplastic cells are usually stained A ?reen B 'urple C Blue D 'in! 8adpole cells are obser"ed in A %n"asi"e squamous carcinoma of cer"i2 B &i3h 3rade squamous precursor lesions C Both in"asi"e squamous carcinoma of cer"i2 and &i3h 3rade squamous precursor lesions

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9either in"asi"e squamous carcinoma of cer"i2 and &i3h 3rade squamous precursor lesions

BATCH 5 (02/0") YEAR 2 SEMESTER 2 FINAL EXAM EXAM DATE : MONDAY, "TH MARCH 20*0
1 By practicin3 quality assurance A Aor! load can be reduced B @alse results can be minimised C Cytotechnolo3ist can be reduced D 8he cost of 'A' smear can be reduced 1ali3nancy criteria of three dimensions seen in A &i3h 4%= B Adenocarcinoma C Carcinoma Cin;situ D %n"asi"e squamous cell carcinoma Cytolo3y test records should be retained in the laboratory for atleast .......... years A /ne B 8wo C @our D @i"e $ A maDor problem with con"entional 'A' smear is A Bac!3round full of mucus B <2pensi"e procedure C 8ime consumin3 D Chance of cell loss durin3 samplin3 'roliferation of cancer cell to distant or3ans is called

A B C D *

%n"asion 1etaplasia 1etastasis Keratinisation

@ollowin3 are ris! factors for de"elopin3 cer"ical cancer EXCE!T A 1ultiple se2ual partners B &4( infection C &'( infection D 're"ious abnormal smear @ollowin3 fi2ati"es can be used for a cytolo3y smear EXCE!T A 7- : alcohol B 1, : formalin C Cytospray D 1,, : alcohol

@ollowin3 solutions can be used as bluin3 a3ent EXCE!T A 4cottEs solution B 4odium bicarbonate C 8ap water D Acid alcohol ............ are used to detemine the adequacy of 'A' smear A 4quamous epithelial cells. B <ndocer"ical cells C 9eoplastic cells D <2ocer"ical cells 1ost onco3enic &'( is A 8ype 1 B 8ype * C 8ype 1* D 8ype 11 8he physiolo3ical con"ersion of columnar endocer"ical cells to flat e2ocer"ical cells is termed A 1etaplasia B Atypia C 1etastasis D 'ara!eratosis =ar3e cancer cells with 3round 3lass appearance6 fairly 3ranular "acuolated cytoplasm6 lar3e "esicular nucleus6 with remar!ably lar3e irre3ular nucleoli C su33ests ............ A ?lassy cell carcinoma B 1ucoepidermoid carcinoma C 4mall cell carcinoma D 9one of the abo"e

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10

8he followin3 are cellular chan3es caused by &'( EXCE!T A 9uclear mouldin3 B &yperchromatic nuclei C 'erinuclear halo D &yperse3mentation Bntreated precursor lesions usually ta!e ......... to pro3ress to in"asi"e cancer A 4e"eral days B 4e"eral wee!s C 4e"eral months D 4e"eral years Actinomycetes are usually associated with the use of A %BCD B &'( infection C &ormone replacement treatment D 8ampon

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4creenin3 of cytolo3y slides to assess cellularity6 stain quality6 distribution of cells are done at ......... ma3nification A 1,F B 2,F C $,F D 1,,F Diff quic! utilises A Air dried specimen B Alcohol fi2ed specimen C @ormalin fi2ed specimen D Dichromate fi2ed specimen 8he term aniso!aryosis refers to si3nificant "ariation in A Cell si#e B Cell shape C 9ucleoli si#e ) shape D 9uclear si#e ) shape 8he technique for inspection of "ascular chan3es on the surface of cer"i2 is A Colposcopy B Colonoscopy C =aryn3oscopy D Bronchoscopy 8he Bethesda system report includes A 4pecimen adequacy B <"idence of infection C <"idence of premali3nant lesions

10

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All of the abo"e

4u33estion 3i"en in Bethesda system for adenocarcinoma A Refer 3ynaecolo3ist B Repeat smear at the earliest C Repeat smear after months D Repeat smear after * months /? * ) <A -, are A 9uclear stains B Counter stains C &aematolo3ical stains D &istolo3ical stains 9uclear enlar3ement in otherwise normally appearin3 cells is termed A Dys!aryotic B Karyome3aly C Koilocytosis D Keratosis %n normal 'A' smear6 mature metaplastic cells are usually stained A ?reen B 'urple C Blue D 'in! 8he probable reason for delay in cytolo3y report could be A @urther test to be done to confirm dia3nosis B Aaitin3 for doctor si3nature C Aaitin3 for data entry to be completed D Aaitin3 for more samples

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BATCH 5 (02/0") YEAR 2 SEMESTER 2 *ST REFERRAL EXAM EXAM DATE : TUESDAY, 27TH A!RIL 20*0
1 Ahich of the followin3 stain is not in co;operated in <A;-, G A <osin H B =i3ht ?reen 4@ C &aemato2ylin D Bismarc! brown <nlar3ement of nuclei with normal cytoplasm is termed ............ A Karyome3aly B Aniso!aryosis C Cytome3aly D 'ara!eratosis

12

%f there is a delay in deli"ery lon3er than ...........6 cytolo3ical specimens should be refri3erated A 1, mins B 2, mins C , mins D $, mins $ Cytolo3ical results should be !ept as record for atleast ........ A * months B 1 year C 2 Hears D - Hears 8he standard nuclear stain used in 'A' stain is6 A <osin B &aemato2ylin C /ran3e ? D <osin A#ure @ind the statement +,) )#-% for 1ali3nant lesion A =imited proliferation. B %n"ade surroundin3 tissues C 1etastasi#e. D Bnlimited proliferation.

Aell preser"ed RBCs in cytolo3ic smears indicate : A Acute inflammatory process B Aller3ic reaction C 1enstrual bleedin3 D '%D
%dentify the ./01% statement re3ardin3 mountant. A Acts as a permanent bond between slide and co"erslip6 B Acts as a fi2ati"e C Acts as a seal a3ainst o2idation and fadin3 of the stain. D protects cell material from air dryin3 and shrin!a3e ?rade % in cancer indicates the cancer is ............. A 'oorely differentiated B 1oderately differentiated C Aell differentiated D Bad pro3nosis A 'A' smear is considered satisfactory if ............ cells are found A 4quamous epithelial cells. B <ndocer"ical cells C 9eoplastic cells D <2ocer"ical cells

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8o minimi#e cellular distortion and reduce cell loss from slide6 A 4mears are fi2ed B 4mears are 3radually dehydrated C 4mears are bluened D 4mears are stained 8he cytoplasm of !eartinisin3 squamous cells are stained ............... A Blue B ?reen C 'in! D /ran3e 1ost onco3enic &'( is A 8ype 1 B 8ype * C 8ype 1* D 8ype 11

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By practicin3 quality assurance A Aor! load can be reduced B @alse results can be minimised C Cytotechnolo3ist can be reduced D 8he cost of 'A' smear can be reduced 8he 'ap stain is a: A 1ultichromatic stainin3 technique B 1onochromatic stainin3 technique C 1etachromatic stainin3 technique D Dichromatic stainin3 technique 1ali3nancy criteria of three dimensions seen in A &i3h 4%= B Adenocarcinoma C Carcinoma Cin;situ D %n"asi"e squamous cell carcinoma .......... are enlar3ed squamous cells with hyperchromatic nuclei and a lar3e perinuclear clear halo A 1yelocytes B Koilocytes C 1onocytes D 8ar3et cells 'ic! up the characteristic cytolo3ic feature after radiation A (acuolisation of cytoplasm or occasionally of the nucleus B 1ultinucleation. C Appearance of bi#arre cell forms. D All of the abo"e

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'roliferation of cancer cell to distant or3ans is called A %n"asion B 1etaplasia C 1etastasis D Keratinisation Diff;Iui! is utili#ed on: A Air;dried specimens B Alcohol;fi2ed specimens C @ormalin fi2ed specimens D Dichromate fi2ed specimens @or detailed e2amination in cytolo3y6 ........obDecti"e lens are used A 1, F B 2, F C $, F D 1,, F Cells arran3ed in parallel clusters are called A 'allisade B Rosette C 'arallels D Dysplastic %n the Bethesda system of classification6 low;3rade squamous intraepithelial lesion J=4%=K indicates : A Cancer B 1ild dysplasia C 1oderate dysplasia D 4e"ere dysplasia Ahich one of the followin3 statement is true re3ardin3 Bismarc! brown in 'A' stain A 4tains cytoplasm of mature squamous cells B 4tains cytoplasm of parabasal squamous cells C 4tains cytoplasm of intermediate squamous cells D &as no specific stainin3 to cytoplasm

2,

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%dentify the cell. A B C D 4i3net rin3 cell Koilocytes 'alisade formation &istiocytes

BATCH 2 (03/0") YEAR 2 SEMESTER 2, MID SEMESTER EXAM EXAM DATE : THURSDAY, **TH MARCH 20*0
1 By practicin3 quality assurance A Aor! load can be reduced B @alse results can be minimised C Cytotechnolo3ist can be reduced D 8he cost of 'A' smear can be reduced Bterine fibroids are an e2ample of a A Beni3n lesion B 1ali3nant lesion C Carcinoma insitu D 9one 'ituitary adenoma is deri"ed from A 4quamous epithelium B ?landular epitheliun C Both

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D $

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1ost onco3enic &'( is A 8ype 1 B 8ype * C 8ype 1* D 8ype 11 @ormation of squamous pearls6 binucleation ) sli3ht enlar3ement of nuclei are the characters of A Koilocytes B 'apilloma C 'ara!eratosis D 'olyp Ahich one of the followin3 is a fa"ourable pro3nosis A %n"asion of lymphatics B =ymphocytic infilterate C 1etastasis to re3ional lymph node D %n"asion of blood "essels 'roliferation of cancer cell to distant or3ans is called A %n"asion B 1etaplasia C 1etastasis D Keratinisation

Bntreated precursor lesions usually ta!e ......... to pro3ress to in"asi"e cancer A 4e"eral days B 4e"eral wee!s C 4e"eral months D 4e"eral years ............ are used to detemine the adequacy of 'A' smear A 4quamous epithelial cells. B <ndocer"ical cells C 9eoplastic cells D <2ocer"ical cells 8he followin3 are cellular chan3es caused by &'( EXCE!T A 9uclear mouldin3 B &yperchromatic nuclei C 'erinuclear halo D &yperse3mentation 8he physiolo3ical con"ersion of columnar endocer"ical cells to flat e2ocer"ical cells is termed A 1etaplasia B Atypia

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C D 12

1etastasis 'ara!eratosis

1inimal acceptable e"idence of samplin3 is identification of atleast .......endocer"ical cells or squamous metaplastic cells A 1, B 2, C , D $, =ow 3rade squamous intraepithelial lesions are associated with the followin3 E&'%() A 1ild dysplasia B &yperchromatic nuclei C Koiloytes D 'seudoeosinophilia 4mall cell carcinoma is 3raded as A Grade 1 B Grade 2 C Grade 3 D Grade 4 9uclear enlar3ement in otherwise normally appearin3 cells is termed A Dys!aryotic B Karyome3aly C Koilocytosis D !eratosis

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Ahich of the followin3 is not resultin3 from the effect of Radiation A Cellular baloonin3 B 9uclear Baloonin3 C (acuolisation of Cytoplasm ) 9ucleus D Denucleation %n"asi"e cer"ical carcinoma should be confirmed by A Blood test B Biopsy C Brine test D Bltrasound 8he term aniso!aryosis refers to si3nificant "ariation in A Cell si#e B Cell shape C 9ucleoli si#e ) shape D 9uclear si#e ) shape 8he technique for inspection of "ascular chan3es on the surface of cer"i2 is A Colposcopy

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B C D 2,

Colonoscopy =aryn3oscopy Bronchoscopy

8he Bethesda system report includes A 4pecimen adequacy B <"idence of infection C <"idence of premali3nant lesions D All of the abo"e 4u33estion 3i"en in Bethesda system for adenocarcinoma A Refer 3ynaecolo3ist B Repeat smear at the earliest C Repeat smear after months D Repeat smear after * months Below rea3ent can be used as bluin3 rea3ent in 'A' stainin3 %&'%() A 4cottEs 4olution B 8ap water C 4odium Bicarbonate D Acid alcohol .............. is a premali3nant lesion6limited to top layer at the cer"i2L does not in"ade6 1,,: cure rate if completely remo"ed. A 4quamous cell carcinoma B Carcinoma in situ C Adenocarcinoma D ?enital warts Ad"anta3es of con"entional method 'A' smear is A <asy to perform B 8hic! smear C %ndi"idual "ariation D =ow cost Beni3n endometrial cells are characterised by A 4li3ht anisonucleosis B 4mall cluster6hyperchromatic crowded 3roups C Dirty bac!3round D ?ranular cytoplasm

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BATCH 2 (03/0") YEAR 2 SEMESTER 2, FINAL EXAM EXAM DATE : 3EDNESDAY , 2ND 4UNE 20*0
1 Ahich of the followin3 stains is not in co;operated in <A;-,G A <osin H

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B C D 2

=i3ht ?reen 4@ &aemato2ylin Bismarc! brown

<nlar3ement of nuclei with normal cytoplasm is termed ............ A Karyome3aly B Aniso!aryosis C Cytome3aly D 'ara!eratosis %f there is a delay in deli"ery lon3er than ...........6 cytolo3ical specimens should be refri3erated A 1, mins B 2, mins C , mins D $, mins

Cytolo3ical results should be !ept as record for at least ........ A * months B 1 year C 2 Hears D - Hears 8he standard nuclear stain used in 'A' stain is A <osin B &aemato2ylin C /ran3e ? D <osin A#ure @ind the statement +,) )#-% for mali3nant lesion A =imited proliferation. B %n"ade surroundin3 tissues C 1etastasi#e. D Bnlimited proliferation.

Aell preser"ed RBCs in cytolo3ic smears indicate A Acute inflammatory process B Aller3ic reaction C 1enstrual bleedin3 D '%D
%dentify the ./01% statement re3ardin3 mountant A Acts as a permanent bond between slide and co"erslip6 B Acts as a fi2ati"e C Acts as a seal a3ainst o2idation and fadin3 of the stain. D protects cell material from air dryin3 and shrin!a3e ?rade % in cancer indicates that the cancer is ............. A 'oorly differentiated B 1oderately differentiated

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C D 1,

Aell differentiated Bad pro3nosis

A 'A' smear is considered satisfactory if ............ cells are found A 4quamous epithelial cells. B <ndocer"ical cells C 9eoplastic cells D <2ocer"ical cells 8o minimi#e cellular distortion and reduce cell loss from slide6 A 4mears are fi2ed B 4mears are 3radually dehydrated C 4mears are bluened D 4mears are stained 8he cytoplasm of !eratinisin3 squamous cells are stained ............... A Blue B ?reen C 'in! D /ran3e 1ost onco3enic &'( is A 8ype 1 B 8ype * C 8ype 1* D 8ype 11

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By practicin3 quality assurance A Aor! load can be reduced B @alse results can be minimised C Cytotechnolo3ist can be reduced D 8he cost of 'A' smear can be reduced 8he 'ap stain is a: A 1ultichromatic stainin3 technique B 1onochromatic stainin3 technique C 1etachromatic stainin3 technique D Dichromatic stainin3 technique 1ali3nancy criteria of three dimensions seen in A &i3h 4%= B Adenocarcinoma C Carcinoma Cin;situ D %n"asi"e squamous cell carcinoma .......... are enlar3ed squamous cells with hyperchromatic nuclei and a lar3e perinuclear clear halo A 1yelocytes

1-

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B C D 1+

Koilocytes 1onocytes 8ar3et cells

'ic! up the characteristic cytolo3ic feature after radiation A (acuolisation of cytoplasm or occasionally of the nucleus B 1ultinucleation. C Appearance of bi#arre cell forms. D All of the abo"e 'roliferation of cancer cell to distant or3ans is called A %n"asion B 1etaplasia C 1etastasis D Keratinisation Diff;Iui! is utili#ed on: A Air;dried specimens B Alcohol;fi2ed specimens C @ormalin fi2ed specimens D Dichromate fi2ed specimens @or detailed e2amination in cytolo3y6 ........obDecti"e lens are used A 1, F B 2, F C $, F D 1,, F Cells arran3ed in parallel clusters are called A 'allisade B Rosette C 'arallels D Dysplastic %n the Bethesda system of classification6 low;3rade squamous intraepithelial lesion J=4%=K indicates : A Cancer B 1ild dysplasia C 1oderate dysplasia D 4e"ere dysplasia Ahich one of the followin3 statement is true re3ardin3 Bismarc! brown in 'A' stain A 4tains cytoplasm of mature squamous cells B 4tains cytoplasm of parabasal squamous cells C 4tains cytoplasm of intermediate squamous cells D &as no specific stainin3 to cytoplasm

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%dentify the cell. A B C D 4i3net rin3 cell Koilocytes 'alisade formation &istiocytes

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