Biol.

303

EXAM I

9/21/09

Name___________________________________

-------------------------------------------------------------------------------------------------------------This exam consists of 0 m!lti"le choice #!estions $o%th 2.& "oints each. 'n the separate answer sheet( "lease fill-in the sin)le *est choice fo% each #!estion. Please bubble-in
your name on the answer sheet, leaving a space between first and last names. Also, bubble-in the last 5 digits of your social security number under ID N !"#$% beginning in the left-most column. +oo, l!c-.

-------------------------------------------------------------------------------------------------------------1. E!-a%/otic cells ,iffe% f%om "%o-a%/otic cells in that A. B. 2. 1. onl/ "%o-a%/otes ha0e 1NA. onl/ "%o-a%/otes ha0e a t%!e n!cle!s. onl/ e!-a%/otic cells contain )enetic mate%ial. None of the a*o0e.

2. If t$o ch%omosomes of a s"ecies a%e the same len)th an, ha0e simila% cent%ome%e "lacements *!t a%e not homolo)o!s( then $hat is ,iffe%ent a*o!t them3 A. B. 2. 1. The/ ,o not contain simila% )enes. 'ne contains 1NA an, the othe% ,oes not. 'ne contains " a%ms $hile the othe% contains # a%ms. 'ne is an X ch%omosome an, one is a 4 ch%omosome.

Use the following information for questions 3 and 45 A ,i"loi, somatic cell f%om a ce%tain %o,ent has a total of 3. ch%omosomes.

6hat is the total n!m*e% of telome%es in the %o,ent cell in +13 A. B. 77 2. 32 1. 187

6hat is the total n!m*e% of cent%ome%es in a s"e%m cell f%om this %o,ent3 A. 21 B. 22 2. 1. 77

&. A "lace in the e!-a%/otic cell c/cle at $hich a 9,ecision9 is ma,e $hethe% to "%ocee, th%o!)h the cell c/cle o% to a%%est cell c/cle "%o)%ession is )ene%all/ -no$n as

A. B. 2. 1. 8.

: "hase +1 "hase a chec-"oint mitosis

6hich ste" of meiosis cont%i*!tes to si)nificant )enetic 0a%iation3 A. B. 2. 1. None( since meiosis no%mall/ "%o,!ces )eneticall/ i,entical cells. Telo"hase I ;%o"hase I Meta"hase II

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6hat is one ,iffe%ence *et$een mitosis an, meiosis3 A. Meiosis in0ol0es t$o cell ,i0isions $hile mitosis in0ol0es one. B. The "%o,!cts of mitosis a%e no%mall/ ha"loi,. 2. The "%o,!cts of meiosis a%e ,i"loi, 1. Mitosis "%o,!ces fo!% cells( $hile meiosis "%o,!ces t$o.

7.

The te%m synapsis %efe%s to A. B. 2. 1. ti)ht "ai%in) of homolo)o!s ch%omosomes ,!%in) meiosis. ti)ht "ai%in) of homolo)o!s ch%omosomes ,!%in) mitosis. ti)ht "ai%in) of nonhomolo)o!s ch%omosomes ,!%in) meiosis. non,is=!nctions.

9.

An allele is A. B. 2. 1. a t/"e of cell. a ,ominant t%ait. a fo%m of a )ene. an ima)ina%/ conce"t.

10. 6hat is the "%o*a*ilit/ that in an o%)anism $ith a ha"loi, n!m*e% of 12( an e)) $ill *e fo%me, that contains all 12 ch%omosomes $hose cent%ome%es $e%e ,e%i0e, f%om mate%nal homolo)s3

A. B. 2. 1.

>1/12?2 >1/10?12 >1/2?12 None of the a*o0e.

11. The fi)!%e *elo$ sho$s a ch%omosomal se"a%ation ta-in) "lace. @ittle ci%cles %e"%esent cent%ome%es. The lette%s stan, fo% )enesA ca"ital an, lo$e%case stan, fo% ,iffe%ent alleles. 2n in this o%)anism is . 6hat "%ocess is sho$n3 A. B. 2. 1. ana"hase of mitosis telo"hase of meiosis I ana"hase of meiosis I ana"hase of meiosis II

12. In each of Men,elBs monoh/*%i, c%osses of "ea "lants( the t%ait that ,isa""ea%e, in the C1 )ene%ation A. ill!st%ate, the "%inci"le of in,e"en,ent asso%tment. B. ,isa""ea%e, in the C2 )ene%ation. 2. a""ea%e, in 1/ of the "lants in C2 )ene%ation. 1. $as ,ominant. In each one of Men,elBs ,ih/*%i, c%osses( A. B. 2. 1. sim"le ,ominance an, %ecessi0eness $as o*se%0e,. the "henot/"es in the C2 )ene%ation se)%e)ate, in a 9535351 %atio. e"istasis $as not e0i,ent. all of the a*o0e.

13.

1 . In a c%oss *et$een t$o "lants of the follo$in) )enot/"es5 >AaBb x AaBb?( $hich one of the follo$in) )enot/"es sho!l, occ!% at the hi)hest f%e#!enc/ amon) the offs"%in)3 A. B. 2. 1. AaBb AABb AABB aabb

1&.

In the c%oss >AaBb x AaBb?( the )enot/"e aabb sho!l, occ!% at $hat f%e#!enc/3 A. B. 2. 1. 1/ 1/7 1/2 1/18

18.

A 9535351 %atio of "henot/"es in the C2 )ene%ation of a ,ih/*%i, c%oss A. hol,s t%!e onl/ fo% )enes on the same ch%omosome. B. in,icates that the ,ih/*%i, c%oss is *asicall/ e#!i0alent to t$o in,e"en,ent monoh/*%i, c%osses. 2. is in,icati0e of com"lete lin-a)e. 1. in,icates that an e"istatic %elationshi" exists *et$een the t$o )enes !n,e% in0esti)ation.

1<. The chi-s#!a%e test in0ol0es statistical com"a%ison *et$een o*se%0e, 0e%s!s ex"ecte, 0al!es. In a chi-s#!a%e test( one ,oes not %e=ect the n!ll h/"othesis if A. B. 2. 1. " D 0.0& " D &.0 "E# it is C%i,a/

17. Al*inism in h!mans is inhe%ite, as a sim"le a!tosomal %ecessi0e t%ait. T$o no%mal "a%ents ha0e fi0e chil,%en an, one is al*ino. If the ,ominant an, %ecessi0e alleles fo% al*inism a%e ,esi)nate, as A an, a %es"ecti0el/( then the )enot/"es of the "a%ents can *e5 A. F E AA G E Aa F E mom G E ,a,

B. F E AA G E aa 2. F E aa G E aa 1. F E Aa G E Aa 19. A tall( 0iolet "lant is c%osse, $ith a ,$a%f( $hite "lant an, all of the C1 offs"%in) a%e tall( 0iolet. The C1 "lants a%e selfe, to "%o,!ce the C2 )ene%ation. 6hat f%action of the C2 )ene%ation $o!l, /o! ex"ect to *e ,$a%f( 0iolet3 >Ass!me in,e"en,ent asso%tment.? A. B. 2. 1. 1/ 9/18 3/18 1/18

20. Ho$ man/ ,iffe%ent t/"es of )ametes can *e fo%me, */ an in,i0i,!al of the follo$in) )enot/"e5 AaBbCcDdEeFF3 A. B. 2. 1. 28 E 8 & 2& E 32 &2 E 2&

21. A male cat has sho%t hai%( a st!**/ tail( an, ext%a toes. A female cat has lon) hai%( a lon) tail( an, ext%a toes. The )enes an, alleles a%e as follo$s5 L E sho%t hai%A l E lon) hai% M E st!**/ tailA m E lon) tail P E ext%a toesA p E no%mal n!m*e% of toes The t$o cats ha0e -ittens. 'ne -itten has lon) hai%( a lon) tail( an, a no%mal n!m*e% of toes. 6hat is the )enot/"e of the fathe%3 A. B. 2. 1. LL MM PP Ll Mm PP ll mm pp Ll Mm Pp

22. Ie,-)%een colo% *lin,ness is X-lin-e, %ecessi0e. A colo%-*lin, $oman has chil,%en $ith a man ha0in) no%mal 0ision. 6hich statement is co%%ect3 A. No ,a!)hte% sho!l, *e colo%*lin,. B. All sons sho!l, *e colo%*lin,.

2. The $omanJs fathe% $as colo%*lin,. 1. All of the a*o0e. 23. 2onsi,e% th%ee in,e"en,entl/ asso%tin) )enes A, B( an, C. 6hat is the "%o*a*ilit/ of o*tainin) an offs"%in) that is AaBBCc f%om "a%ents that a%e AABbCc an, AaBbCc3 A. 1/7 B 1/ 2. 1/18 1. 1/32 2 . 2onsi,e% the follo$in) "e,i)%ee5

The t%ait ,e"icte, in the a*o0e "e,i)%ee is li-el/5 A. B. 2. 1. a!tosomal %ecessi0e sex-lin-e, %ecessi0e a!tosomal ,ominant sex-lin-e, ,ominant

2&. In the a*o0e "e,i)%ee( $hat is the )enot/"e of the in,i0i,!al "ointe, o!t3 >The %ele0ant )ene has alleles A an, a.? A. AA B. Aa 2. aa 1. 2anJt tell 28. A $oman an, a man a%e *oth hete%oK/)o!s fo% f%ec-les( $hich is the ,ominant con,ition. If the/ ha0e one chil,( $hat a%e the chances that it $ill ha0e f%ec-les3 A. 2&L B. &0L

2. It $ill ,e"en, on the sex of the chil,. 1. <&L 2<. Co% the "e,i)%ee sho$n *elo$5

$hich one of the follo$in) mo,es of inhe%itance can *e %!le, o!t3 A. B. 2. 1. 27. X- lin-e, ,ominant X lin-e, %ecessi0e A!tosomal ,ominant All of the a*o0e a%e "ossi*le.

:ho$n *elo$ is a "e,i)%ee fo% the %a%e a!tosomal %ecessi0e ,isease calle, Ta/-:achs5

)enot/"e Tt? 2onsi,e% the $oman $ho is "ointe, o!t in the "e,i)%ee. If the )ene %es"onsi*le fo% Ta/-:achs ,isease can *e s/m*oliKe, */ alleles T an, t( $hat is the "%o*a*ilit/ that the $omanJs )enot/"e is Tt3 A. 1/ B. 1/2 2. 2/3 1. No chance( *eca!se she m!st *e TT 29. 6ith incomplete dominance( a li-el/ C2 "henot/"ic %atio in a monoh/*%i, c%oss $o!l, *e5 A. 351 B. 152525 2. 15251 1. 9535351

30.

The ,iffe%ence *et$een incomplete dominance an, codominance is A. Nothin)( the/ a%e the same B. 'nl/ incom"lete ,ominance in0ol0es hete%oK/)otes ,is"la/in) a *len,in) of "henot/"es 2. 'nl/ co,ominance in0ol0es hete%oK/)otes $ith a *len,in) of "henot/"es 1. 2o,ominance "%o,!ces classic Men,elian %atios $hile incom"lete ,ominance ,oes not.

31

A con,ition in $hich one )ene infl!ences the ex"%ession of anothe% )ene is calle, A. B. 2. 1. co,ominance. ,ominance. %ecessi0eness. e"istasis.

32. If a chil, is *loo, t/"e A an, the mothe% is *loo, t/"e B( $hat is the most li-el/ *loo, t/"e of the fathe%3 A. B. 2. 1. A B A or AB O

33. :!""ose that an allele( b( of a sex-lin-e, )ene is %ecessi0e an, em*%/onic lethal >em*%/onic lethal means ,eath at the em*%/onic sta)e of ,e0elo"ment?. A man ma%%ies a $oman $ho is hete%oK/)o!s fo% this )ene. If this co!"le ha, a la%)e n!m*e% of chil,%en( $hat $o!l, *e the "%e,icte, %atio of male chil,%en to female chil,%en3 A. B. 2. 1. 3 . 151 152 252 15

In Msex-infl!ence, inhe%itance(N A. B. 2. 1. a t%ait can *e ex"%esse, in one sex onl/. a )i0en )enot/"e "%o,!ces a ,iffe%ent "henot/"e in males 0e%s!s females. a )i0en t%ait is on the X ch%omosome. fathe%s ne0e% "ass the t%ait to sons.

3&.

6hen t$o )enes fail to asso%t in,e"en,entl/( the te%m no%mall/ a""lie, is

A. B. 2. 1. 38.

Men,elian inhe%itance. lin-a)e. incom"lete ,ominance. com"lementation.

6hich statement is t%!e3 A. t$o )enes on the same ch%omosome can asso%t in,e"en,entl/ f%om one anothe%. B. t$o )enes on ,iffe%ent ch%omosomes $ill asso%t in,e"en,entl/ f%om one anothe%. 2. t$o )enes close to each othe% on the same ch%omosome $ill "%o*a*l/ not ,is"la/ in,e"en,ent asso%tment. 1. all of the a*o0e.

3<. The %ecom*ination f%e#!enc/ *et$een lin-e, )enes A an, B is 0L( *et$een B an, C is 20L( *et$een C an, D is 10L( *et$een C an, A is 20L( an, *et$een D an, B is 10L. 6hat is the se#!ence of the )enes on the ch%omosome3 A. B. 2. 1. A B A A B A D C C D C D D C B B

37. In a t/"ical th%ee facto% c%oss *et$een a hete%oK/)o!s female an, a homoK/)o!s %ecessi0e male( offs"%in) a%isin) f%om non-c%osso0e% >"a%ental t/"e? )ametes $ill *e A. B. 2. 1. the most common offs"%in) the least common offs"%in) females onl/ "%o*lem chil,%en

39. A female f%!it fl/ hete%oK/)o!s fo% th%ee lin-e, m!tant alleles a,b,c, >)enot/"e AaBbCc? is c%osse, $ith a male fl/ that is homoK/)o!s %ecessi0e fo% all th%ee m!tant alleles. If the phenotypes of the most common offs"%in) a%e ABc an, abC( an, the least common offs"%in) a%e ABC an, abc( then the o%,e% of the )enes a b c on the ch%omosome is5 A. a b c B. b a c

2. b c a 1. not eno!)h info%mation to tell. 0. 2onsi,e% the follo$in) ta*le of ,ata f%om a synteny test !sin) mo!se/h!man h/*%i, cells fo% assi)nin) )enes to h!man ch%omosomes. -----------------------------------------------------------------------------------h/*%i, h!man ch%omosomes h!man )ene "%o,!ct cell5 "%esent5 "%esent5 I 1 2 3 & 8 A B II 1 3 < 7 9 A B 2 III 1 2 < 7 A -----------------------------------------------------------------------------------Base, on the a*o0e ,ata( the )ene that "%o,!ces "%o,!ct 2 is locate, on h!man ch%omosome n!m*e%5 A. 1 B. 2 2. 9 1. canBt tell. Thats All!

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http://network.nature.com/people/strippedscience/blog/2008/06/20/the-young-mendel-comic-strip

Answer Key

Q: 1, 2, 3, 4, 5, 6, 7, 8, 9,10,11,12,13,14,15,16,17,18,19,20, A: D, A, B, B, C, C, A, A, C, C, D, C, D, A, D B, A, D, C, C, Q:21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40 A: D, D, C, C, B, D, B, C, C, B, D, C, B, B, B, D, D, A, C, C