SECTION A 1. a. b. c. d. 2. a. b. c. d. 3. a. b. c. d. ". a. b. c. d. %. a. b. c. d. Which device transforms mechanical energy into electrical energy?

generator motor transformer mass spectrometer The use of biodiesel contributes to a reduction in carbon emissions because the biodiesel manufacturing process uses electricity biodiesel produces no CO2 upon combustion the plants from which biodiesel is made absorb CO2 diesel engines are more efficient than petrol engines Which organ in the human body helps us sense acceleration? The eyes The ears The s in !one. We cannot directly sense acceleration. We wear special glasses when watching 3#$ movies at a theatre because 3#$ movies use special colors which cannot be sensed by the human eye 3#$ movies are brighter than ordinary movies and can hurt our eyes if seen directly the glasses allow our left and right eyes to see different images none of the above &ossils of sea creatures are sometimes found on high mountain tops. The most li ely e'planation for this is( sea levels were much higher in the past land that once formed the sea floor was slowly pushed upwards to form the mountain intermittent )great floods* moved sea creatures onto mountain tops the fossils are actually of land animals that resemble sea creatures

+. a. b. c. d. 0. a. b. c. d. 3. a. b. c. d. 6. a. b. c. d. 11. a. b. c. d.

, sundial meant to be used in -umbai cannot be used in .toc holm because the two cities are in different time /ones the two cities are at different altitudes there isn*t enough sunlight in .toc holm the two cities are at different latitudes The sum of all integral numbers from 1 to 1121112111 is 212111211121112111 232"%+20302+%"2321 %12111211%21112111 21121112111 , ball point pen and an in #pen have the same amount of their respective in s in them. Which one can be used to write more on paper? 4all point pen 5n #pen 4oth can be used to write to the same e'tent 5t depends upon the paper and in color Which of the following statements is true?
3 3 2 1 / 2 1/ 2 2 3 3 2 2 1 / 2 1 / 2 3 3 2 1 / 2 1/ 2 2 3 3 2 2 1 / 2 1/ 2

5n a family in Tindivanam2 the parents and all four children lac eyebrows. 5t can be concluded that the underlying cause is genetic cultural a contagious disease any of the above

11. a. b. c. d. 12. a. b. c. d.

Which of the following spheres will roll down an inclined plain slowest? , solid copper ball , hollow copper sphere of the same diameter as above with mercury to compensate for weight , hollow copper ball filled with a lead ball inside to compensate for weight , hollow copper ball without weight compensation We only see one side of the moon because we live in the northern hemisphere the earth*s gravity attracts one side of the moon more strongly the moon rates of rotation and orbital revolution happen to be e7ual it is an optical illusion

13. a. b. c. d. 1".

, s7uare has a side of 1 cm. ,n e7uilateral triangle with the same area has a base of

" /3 3/ " 3/ " " /3

cm cm cm cm

Two identical containers , and 4 hold e7ual amounts of water. 5nitially2 the water in container , is at 018C2 and the water in container 4 is at 318C. !ow we cool both containers in the same room. Which of the following is true? The water in container , cools slower than in container 4 The water in container , cools faster than in container 4 The water in container , cools at same rate as in container 4 !one of the above , mon ey e'periences fear the first time it sees a sna e. This is because( the mon ey has learned to beware of sna es from its parents the mon ey is frightened by any novel e'periences natural selection has lead to mon eys having an instinctive fear of sna es the mon ey logically deduces that the sna e must be dangerous

a. b. c. d. 1%. a. b. c. d.

SECTION B 1. , stone is tied to a thread of constant length and rotated in a hori/ontal plane. Which of the following 7uantities is not constant in time? 9inetic energy of the stone :otential energy of the stone -omentum of the stone Total energy of the stone , cube shaped ob;ect made of a certain material has sides of 2 m. The ob;ect weighs + g. 5t is slowly lowered into a certain li7uid. What will happen? The ob;ect will sin The ob;ect will float 5t depends on the properties of the li7uid 5t depends on whether the ob;ect is hollow or solid , ball is thrown up with a velocity of 21 m<s. =ow long will it be before the ball returns to the ground? ,ssume gravitational acceleration > 11 m<s2. ?ou can ignore air friction. 1.% s 1s 2s "s What is the e'pected pressure of air in the lungs of a diver at " meters below sea level? 1"1 9pa 1" 9pa "1 9:a " 9:a Two balls on a frictionless surface collide and stic . Which of the following is not conserved? momemtum angular momemtum inetic energy mass

a. b. c. d. 2. a. b. c. d. 3.

a. b. c. d. ". a. b. c. d. %. a. b. c. d.

+.

The diagram below shows a frictionless wheel with a weightless cable wrapped around it and a bloc attached to the end of the cable. The wheel has a mass of +.1 g and the bloc has a mass of 2.1 g. The bloc is released from rest and drops as the cable unwinds. When the bloc has dropped 1.1 m2 its velocity is 2.3 m<s. What is the inetic energy of the wheel?

a. 1 @ b. 3." @ c. 12 @ d. 21 @ 7. .cientists ma e an insulated container to hold ".1 moles of nitrogen at a pressure of 11A% :a and a temperature of 211 9. What is the appro'imate si/e of the container? B1 atm > 111 :aC a. b. c. d. 3. " litres 3 litres 10 litres +0 litres

The radius of the nucleus of an atom of gold is D > +.2'11#1% m. Which of the following e'pressions represent the variation of the magnitude of the electric field from the centre of the nucleus to the outside? B,ssume that the nucleus is spherical and that the charge is distributed uniformly throughout that volumeC. r is the distance from the centre of the nucleus and 7 is the total charge of the nucleus. a. b. c. d. E 7r<D3 outside the nucleusF E7<r2 inside the nucleus E 7<r2 both inside and outside the nucleus E 7<r2 outside the nucleusF E 7r<D3 inside the nucleus E 7r2 inside the nucleusF E 7r outside the nucleus
5

6.

,n elevator starts at the ground floor with two persons2 each weighing 111 9g. One person gets down on the fifth floor. The elevator then continues with the second person to the 11th floor. Which of the following plots best represents the variation in potential energy B:.E.C of the elevator and its contents from the start to the instant the elevator reaches the 11th floor.

a. b. c. d. 11.

BaC BbC BcC Ba G dC 5f the cross sectional area of the aorta of a normal person is 3 cm 2 and the speed of blood is 31 cm<s. 5n contrast2 the typical cross sectional area of a blood capillary is 3 H 11 #0 cm2 and the flow speed in capillary is 1.1% cm<s. =ow many capillaries does the person have?

a. b. c. d. 11.

+ million + billion +11 thousand +11 million &ind the electric field at a distance / above the mid#point of a straight line of length 2I with a uniform charge density J.

a. b. c. d. 12.

E 2J<I2 E 2J</2 E 2JI</2 E 2JI<B/Ks7rtB/2LI2CC Two identical glass slabs .1 and .2 are placed between a laser light source and a detector as shown in the figure below. Each slab transmits %1M of incident light2 and reflects the remaining %1M light. What fraction of the emitted laser light reaches the detector?

a. b. c. d. 13.

1 M Bno light reaches the detectorC Nreater than 2%M E'actly 2%M Iess than 2%M

, lens has focal length L11 cm. ,n ob;ect is placed at a distance 21 cm to the left of the lens. The image is( a. b. c. d. real and 21 cm right of the lens virtual and 21 cm left of the lens real and 11 cm right of the lens virtual and 11 cm left of the lens

1".

The 'ylem system in plants transports water through the stem. ,ssuming that 'ylem tubes are composed of thin2 uniform cylindrical tubes that carry sap entirely due to capillary action with a contact angle of "%1 and surface tension of 1.1% !<m2 what is the ma'imum radius of the tubes for a 21 m tall tree? a. b. c. d. 1.2 H 11#" m ".3 H 11#2 m 3.+ H 11#0 m 2.% H 11#+ m

1%.

What is the ma'imum sustained hori/ontal acceleration possible on a flat trac in a motorcycle whose wheels are 2 m apart centre to centre2 centre of mass symmetrically between the wheels and 1.% m from the ground? ,ssume friction with the road is not limiting. a. b. c. d. 1.% g 1g 2g 5nsufficient information provided.
7

SECTION C 1. 5n case of a unimolecular nucleophilic substitution reaction a. The leaving group departs first before the attac of the nucleophilic reagent b. $eparture of the leaving group and attac of the nucleophilic reagent happens simultaneously c. &irst the nucleophilic reagent attac s before the leaving group departs d. !one of the above 2. Two unstable elements , and 4 have atomic numbers "1 and %+2 respectively. When , emits alpha rays and 4 emits beta rays their atomic numbers will change to( a. b. c. d. 32 33 and %0 "2 and %" "2 and %% !one of the above

=ydrogen bonds are uni7ue among non#covalent interactions because of their a. b. c. d. directional character they are formed from protons the strength of these bonds is e7ual to that of covalent bonds none of the above

".

, planar ring can have aromatic properties if the number of its pi electrons e7uals a. b. c. d. 1" 1+ 12 !one of the above

%.

$ue to the common#ion effect2 the solubility of one salt B.1C a. $ecreases on addition of another salt B.2C because there is an ion common to both .1 and .2 b. 5ncreases on addition of another salt B.2C because there is an ion common to both .1 and .2 c. 5ncreases and then decreases on addition of another salt B.2C because there is an ion common to both .1 and .2 d. !one of the above

+.

The lattice energy of a compound increases as

8

a. b. c. d. 0. a. b. c. d. 3. a. b. c. d. 6.

the distance between the ions decreases the charge on the ions increases all of the above none of the above &or the reaction , 4LC2 at e7uilibrium2 the concentration of , is 1'11# 3 -2 4 is 1.1% - and C is 1.1%-. The ONo* for the hydrolysis of , at 20oC will be #%.1 @<mol #10.3 @<ml #11.2 @<mol !one of the above The half life of radioactive :32 is 1".3 days. 5n how many wee s will the radioactivity fall to 1<1+th of the original value 3.2 wee s 6.0 wee s 0.+ wee s !one of the above -olar absorptivity of potassium chromate at a wavelength of 303 nm is 331% -#1 cm#1. The absorbance B,1C of a solution of this compound Bconcentration >1.%-C was measured using a cuvette of path length >2 cm. ,bsorbance was also measured B,2C of another solution of this compound Bconcentration>1.1-C using a cuvette of path length>1 cm. The relation between ,1 and ,2 can be described as follows

a. b. c. d. 11. a. b. c. d.

,1> 2' ,2 ,1> 1.%' ,2 ,1>,2 !one of the above Which of these is the closest to the value of 1 cal<mole? 2<3 ' 11#21 @oules 2<3 @oules 2 ' 11#21 @oules 3 ' 11#11 @oules

11. a. b. c. d. 12. a. b. c. d. 13.

What is the hybridi/ation of o'ygen in C=3 CO C=3 sp3 sp2 sp ,ll of the above. The peptide bond is planar because of( =ydrogen bonding P bac bonding PQlone pair interaction The hydrophobic effect ,n electron transfer reaction proceeds by diffusion along a solvent coordinate2 followed by an electron tunneling event Bsee figureC. 5f :solv is the probability of the system diffusing from 'D to 'R and :tunneling is the probability of the electron tunneling then the rate constant for electron transfer is proportional to( :solv L :tunneling :solv ' :tunneling :solv # :tunneling :solv < :tunneling

a. b. c. d.

1". a. b. c. d.

,ssuming completely e7uivalent parabolas Bthe e7uations of :1 and :2 are same e'cept for a shift in coordinatesC2 calculate the value of E,S in terms of T and ON1. E,S > T2 < " E,S > BT # ON1C2 < B" ON1C E,S > BT L ON1C2 < B" TC E,S > BON1C2 < T
10

1%. a. b. c. d.

The unit cell in a body centered cubic lattice is given in the figure. Each sphere has a radius2 r2 and the cube has a side2 a. What fraction of the total cube volume is empty? 1 U 3<3 P r3 < a3 "<3 P r3 < a3 r<a 2 # "<3 P r3 < a3

11

SECTION D 1. , couple want to have two children who are genetically identical. .hort of having identical twins engineered2 which of the following statements best describes the number of offspring they should have to allow this? a. b. c. d. 2. 232111 23 2 223111 ,least a billion 5 have a se7uence of $!, that is 2" bp long Bstarts with a start codon and ends with a stop codonC that codes for a protein called -&:. Which of the following statements about the amino acid composition of the protein are false? a. ,dding a 2%h base pair has no effect. b. .ubstituting the +th base may have an effect. c. ,dding a base after the +th base and deleting the 11th base has a smaller effect than each mutation alone. d. ,dding a base after the +th base and deleting the 11th base has greater effect than each mutation alone. 3. ,n alcohol molecule with a five#carbon ring can be chemically modified at positions 32 " and % O!I? to generate biologically active second messengers. The modification can occur either at a single position or in more than one position in combination. =ow many distinct second messenger species can be generated in this manner? a. b. c. d. ". Three &ive .even Two 5 set up a cross between two genetically identical parents hetero/ygous for a recessive mutation that causes the progeny to die as embryos. Which of the following is false? a. b. c. d. %. , 7uarter of the embryos show the mutant phenotype. Three 7uarters of the adult progeny show no phenotype. , third of the adults do not pass on the mutation to the ne't generation. ,ll of the adults are phenotypically indistinguishable. , signalling pathway 5 have identified has three proteins ,2 42 C that wor to allow function H2 When , is absent2 H does not happen. The absence of C or 4
12

individually does not substantially affect function H. When C and 4 are both defective function H fails but can be restored if e'cess , is provided. Which of the following statements is false? a. b. c. d. +. :rotein , functions after proteins C and 4. :rotein , re7uires proteins C and 4. :rotein , re7uires protein C or 4 to function. :roteins C and 4 do not influence each others* function. When bacteria are transformed with $!,2 the effectiveness with which they ta e up $!, is 7uantified as the transformation efficiency. 5f the operational definition of transformation efficiency is the number of bacterial colonies obtained when bacteria are incubated with 1 microgram of $!,. , new student prepared bacterial cells suitable for transformation. On testing his preparation2 he obtained 3111 colonies when he incubated the cells with 3 picograms of $!,. =is transformation efficiency is( a. b. c. d. 0. 1'116 3'11+ 3'116 !one of the above ,t the plasma membrane of a cell the transduction of light is mediated by three proteins ,2 4 and C. , is the sensor and C is the effector. The efficiency of this sensory transduction system is limited by the probability of interaction of , with 4 and 4 with C. 5f the probability of , interacting with 4 is 1.2 and the probability of 4 interacting with C is 1.12 what is the probability of the signal passing from , to C? a. b. c. d. 3. a. b. c. d. 1.2 1.12 1.1 1.113 , species of bacteria found at the bottom of a shallow pond has a hard cell wall and a semi#permeable membrane. Which of the following statements is true? The cell wall prevents the cell from being crushed by e'ternal forces The cell wall prevents the cell from e'ploding due to internal pressure The internal and e'ternal pressure are e7ual2 hence the cell wall determines shape !one of the above

13

6.

:igment colour in guppies is determined genetically. Of the progeny obtained from a guppy pair 2%M e'hibit red pigment2 2%M yellow pigment2 2%M white and 2%M e'hibit orange pigment. 4ased on these observations2 which of the following statements is correct. a. b. c. d. ,lleles for Ded and ?ellow are dominant over white allele Ded and ?ellow are co#dominant alleles One of the parent must have the red pigment ,ll of the above ,n accidental e'posure of a mouse embryo to the VW light results in a green pigment patch in the s in. =owever2 none of the &1 and &2 progeny e'hibit green patches in the s in. The most probable e'planation for this phenomenon is( a. b. c. d. The mutation is repaired in the germ cells This is a somatic mutation and does not get transmitted to the ne't generation The mutant gene is imprinted and hence is not e'pressed in the progeny All of the above , species of a flightless bird found on an island is 11 times bigger than it*s nearest nown mainland relatives. This could be because a. b. c. d. The food on the island is more nutritious Iarger si/e enables more efficient heat dissipation :redators are absent on the island They need to survive e'tended periods without food

11.

11.

12.

5n;ection of an e'tract from the lotus leaves in a rabbit induces immune response. The characteri/ation reveals that some of the antibodies can selectively recogni/e a proto/oan antigen. ,lso the infection assays reveal that the rabbit becomes immune to the proto/oan infection. 4ased on these observations2 it is claimed that lotus leaves have an al aloid that induces production of anti parasitic antibodies. Which of the following observations will wea en this claim substantially? a. The pond water# from where the lotus leaves were ta en# shows very high parasitic count. b. Iotus leaves do not have al aloids that have been previously reported to have anti parasitic activity c. When the lotus leaves samples from %1 different ponds were screened2 only 11 M showed increased antibody production when in;ected in rabbits d. When the un#in;ected rabbits #grown in the laboratories were screened2 1.%M showed antibodies against the parasites.

14

13.

Tight ;unctions are apically placed ;unctions in the epithelial cells. These ;unctions are selectively permeable and regulate the water and electrolyte transport across the epithelium. The Trans#epithelial Electrical Desistance BTEDC measurement reflects how permeable an epithelium is. The TED is inversely correlated with the epithelial permeability. Thus lower TED values are indicative of lea iness of the tight ;unctions. 5t is nown that one of the cholera to'ins called Xot increases the lea iness of the tight ;unctions2 contributing to symptoms of cholera. , pharmaceutical company is screening for bacterial to'ins2 which can enhance the epithelial permeability. Their aim is to use the best of these to'ins as an agent to enhance the transport of an anticancer drug across the intestinal epithelium. 5t is nown that the transport of the drug increases when TED is below %111 ohms. The effects of these " to'ins B&igure ,C and to'inLdrug B&igure 4C on TED were tested on cultured epithelial cells. The treatment started after 3 hours and the to'ins and drugs were washed out after " hours of incubation.
Figure A Figure B

Which of these would you recommend for use in combination with the drug for clinical trials? a. b. c. d. To'in 4 To'in , To'in C To'in $

15

Y1" G 1% , graduate student is attempting to purify an en/yme from the brain of a blowfly. =e grinds up the heads of %11 blowflies in a buffer solution and filters to obtain a crude e'tract. =e then employs two steps of purification to end up with a moderately pure protein. =e estimates en/yme activity at each stage of purification( .tage of :urification Total protein .pecific En/yme in sample BmgC activity Bmoles substrate hydroly/ed<mg protein<minuteC 211 2.% of "1 2% of % 1+1 Total En/yme activity Bmoles substrate hydroly/ed< minuteC %11 1111 311

Crude e'tract ,fter .tep :urification ,fter step purification

1 2

1". a. b. c. d. 1%. a. b. c. d.

Which of the following statements about .tep 1 of purification is TDVE? The data reflect the normally e'pected pattern of a protein purification pro;ect The increase in total en/yme activity is une'pected The decrease in total protein is une'pected The increase in .pecific En/yme activity is une'pected Which of the following statements about the data are plausible? The en/yme being purified constitutes a large fraction of the total e'tracted protein Only a small fraction of the en/yme was recovered in this pro;ect The tissue contains a substance that inhibits the activity of the en/yme There is considerable degradation of protein during .tep 2 of the purification

16