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Pharmacology & anaesthesia (15.04.14) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 Cardiotoxic anticancer drug: Digoxin is excreted through which route (organ): Digitoxin is excreted mainly by which organ DOC for PSVT: Effect on calcium levels of Furosemide: DOC for motion sickness: Commonest side-effect of Cisapride is: Common side-effect of Clofazimine: DOC for taenia: Drug inhibiting DNA-dependent RNA polymerase in Mycobacteria is: Common side-effect of Cisplatin: Vitamin deficiency noticed with phenytoin use: DOC for lithium induced Polyuria Concentration of Lidocaine used in Spinal anaesthesia: Local anaesthetic causing methemoglobinemia: Longest acting local anaesthetic: Anaesthetic agent with LEAST analgesic property: Post spinal headache can last for: Common site of post spinal headache Therapeutic index of a drug is an indicator of its: Common side-effect of Captopril: Active metabolite of Enalapril: Which steroid can be administered by inhalation: Drug used for heparin induced thrombocytopenia Estrogen acts on which receptors: Mydriasis without cycloplegia: Buprenorphine is: Drug for maintenance therapy for opioids withdrawl DOC for diabetes inspidus MOA of minoxidil: Beta blocker with shortest plasma half-life: Pancreatitis is a common side effect of which anti-HIV Drug which cause pulmonary fibrosis: Drug which is used for treating bradyarrythmias: MOA of Cholestyramine: Antifungal which disrupts fungal cell membrane Advantage of 3 rd generation cephalosporins over 1st and 2nd generation cephalosporins is that they are: Fluoroquinolone banned n India: Anti-malarial drug effective in pre-erythrocytic phase in liver is: Effect of chloroquine of eye DOC for herpes simplex ACE inhibitors causes hyperkalemia so they should not be used with Anticoagulant of choice in pregnancy Antidote of heparin Profound analgesia is related to which anaesthetic agent Best way to prevent hypotension during spinal anaesthesia: Post spinal headache is due to: Agent causing malignant hyperthermia: Nerve fibre affected by Local anaesthesia first: Zero order kinetics at higher dose is seen with: DOC for scabies
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drkamalkvs classes: FMGE, DNB & Pre-PG putting Foreign Medical Graduates first
52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 Lithium monitoring is done because of: MOA of pralidoxime Drug used in BPH DOC for acute migraine Test for myasthenia gravis: If Theophylline is used with Ciprofloxacin: Steroid with equal Gluco-corticoid & mineralocorticoid activity: Flumazenil is: Fomepizole is used in which poisoning MC side-effect of chronic use of phenothiazines is: Side effect of Clozapine MOA of clonidine MOA of digoxin DOC for meningitis due to listeria Mode if metabolism of INH Most common side effect of long term use of lithium DOC for MRSA infection ADH acts on which part of kidney: Hemorrhagic cystitis may be a side effect of Metrifonate is used for Anticholinergic drug used in peptic ulcer Postural hypotension is commoner with which adrenergic blocker: Organ toxicity seen with bupivacaine: LEAST cardiotoxic anaesthetic agent: Dissociative anaesthesia is seen with: Sodium Thiopentone is Ultra-short acting due to: Dipyradimole acts by inhibiting Beta 1 agonist drug: Beta1 selective adrenergic blocker which can be used as anti-glaucom Anti-adrenergic drug which crosses blood-brain-barrier minimally: Abacavir belongs to which group of Prostaglandin analogue used in peptic ulcer Prostaglandin analogue used in glaucoma Shortest acting neuromuscular blocking agent: Anaethetic Drug which increase intracranial pressure: Anti-epileptic drug which acts by release of the inhibiting transmitter GABA: Furosemide & thiazides have similar properties that they both are: MOA of ciprofloxacin DOC for WPW syndrome Anti-hypertensive which acts by producing NO MOA of dantrolene sodium Interstitial nephritis is MC seen with which antibiotic: DOC for dermatitis herpetiformis Neuro-psychiatric symptoms can be seen with: Oral contraceptive failure may be seen with: MC side-effect of 5-Fluoro-Uracil: MOA of omeprazole Prolonged use of steroids may cause: First drug to be used in anaphylactic shock:

Answer key 1 Cardiotoxic anticancer drug:

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Adriamycin/ Doxorubicin, Cyclophosphamide, 5facebook page: drkamalkvs classes WhatsApp: 8470004333

drkamalkvs classes: FMGE, DNB & Pre-PG putting Foreign Medical Graduates first
2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 Digoxin is excreted through which route (organ): Digitoxin is excreted mainly by which organ DOC for PSVT: Effect on calcium levels of Furosemide: DOC for motion sickness: Commonest side-effect of Cisapride is: Common side-effect of Clofazimine: DOC for taenia: Drug inhibiting DNA-dependent RNA polymerase in Mycobacteria is: Common side-effect of Cisplatin: Vitamin deficiency noticed with phenytoin use: DOC for lithium induced Polyuria Concentration of Lidocaine used in Spinal anaesthesia: Local anaesthetic causing methemoglobinemia: Longest acting local anaesthetic: Anaesthetic agent with LEAST analgesic property: Post spinal headache can last for: Common site of post spinal headache Therapeutic index of a drug is an indicator of its: Common side-effect of Captopril: Active metabolite of Enalapril: Which steroid can be administered by inhalation: Drug used for heparin induced thrombocytopenia Estrogen acts on which receptors: Mydriasis without cycloplegia: Buprenorphine is: Drug for maintenance therapy for opioids withdrawl DOC for diabetes inspidus MOA of minoxidil: Beta blocker with shortest plasma half-life: Pancreatitis is a common side effect of which anti-HIV Drug which cause pulmonary fibrosis: Drug which is used for treating bradyarrythmias: MOA of Cholestyramine: Antifungal which disrupts fungal cell membrane Advantage of 3 rd generation cephalosporins over 1st and 2nd generation cephalosporins is that they are: Fluoroquinolone banned n India: Anti-malarial drug effective in pre-erythrocytic phase in liver is: Effect of chloroquine of eye DOC for herpes simplex ACE inhibitors causes hyperkalemia so they should not be used with Anticoagulant of choice in pregnancy Antidote of heparin Profound analgesia is related to which anaesthetic agent Best way to prevent hypotension during spinal anaesthesia: Post spinal headache is due to: Agent causing malignant hyperthermia: Nerve fibre affected by Local anaesthesia first: Zero order kinetics at higher dose is seen with: DOC for scabies
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Fluorouracil Renal Liver 1. Adenosine 2. Verapamil Hypercalemia Hyoscine (transdermal) Diarrhea Red brown discoloration of skin Praziquantel Rifampicin Vomiting Folic acid. Vitamin D & some says vitamin K as well Amiloride 5% Prilocaine Dibucaine Halothane 7-10 days Occipital Safety Dry cough Enalaprilat Beclomethasone Argatroban, lepirudin Cytoplasmic receptors Phenyl-ephrine Partial agonist (mu) & antagonist (k) receptors Methadone Desmopressin Potassium channel opener Esmolol Didanosine Busulfan, Bleomycin Atropine Binds to bile acids Griseofulvin Effective against gram negative bacteria Gatifloxacin Proguanil Bulls eye maculopathy Acyclovir Potassium sparing diuretics Heparin Protamine sulphate Ketamine Preloading with crystalloids CSF leak Succinylcholine Type C Phenytoin 5% permethrin
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drkamalkvs classes: FMGE, DNB & Pre-PG putting Foreign Medical Graduates first
52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 Lithium monitoring is done because of: MOA of pralidoxime Drug used in BPH DOC for acute migraine Test for myasthenia gravis: If Theophylline is used with Ciprofloxacin: Steroid with equal Gluco-corticoid & mineralocorticoid activity: Flumazenil is: Fomepizole is used in which poisoning MC side-effect of chronic use of phenothiazines is: Side effect of Clozapine MOA of clonidine MOA of digoxin DOC for meningitis due to listeria Mode if metabolism of INH Most common side effect of long term use of lithium DOC for MRSA infection ADH acts on which part of kidney: Hemorrhagic cystitis may be a side effect of Metrifonate is used for Anticholinergic drug used in peptic ulcer Postural hypotension is commoner with which adrenergic blocker: Organ toxicity seen with bupivacaine: LEAST cardiotoxic anaesthetic agent: Dissociative anaesthesia is seen with: Sodium Thiopentone is Ultra-short acting due to: Dipyradimole acts by inhibiting Beta 1 agonist drug: Beta1 selective adrenergic blocker which can be used as anti-glaucom Anti-adrenergic drug which crosses blood-brain-barrier minimally: Abacavir belongs to which group of Prostaglandin analogue used in peptic ulcer Prostaglandin analogue used in glaucoma Shortest acting neuromuscular blocking agent: Anaethetic Drug which increase intracranial pressure: Anti-epileptic drug which acts by release of the inhibiting transmitter GABA: Furosemide & thiazides have similar properties that they both are: MOA of ciprofloxacin DOC for WPW syndrome Anti-hypertensive which acts by producing NO MOA of dantrolene sodium Interstitial nephritis is MC seen with which antibiotic: DOC for dermatitis herpetiformis Neuro-psychiatric symptoms can be seen with: Oral contraceptive failure may be seen with: MC side-effect of 5-Fluoro-Uracil: MOA of omeprazole Prolonged use of steroids may cause: First drug to be used in anaphylactic shock:
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Very low therapeutic index Cholinesterae enzyme reactvator Prazosin, tamsulosin Sumitriptan Edrophonium test Toxicity of theophylline increases Hydrocortisone Benzodiazepine antagonist Methanol Tardive dyskinesia Agranuocytosis Alpha2 agonist and decreasing central sympathetic outflow Na K ATPase inhibition Ampicillin Acetylation Hypothyroidism Vancomycin Collecting duct Cyclophosphamide Schistosoma Pirenzipine Prazosin Cardiotoxicity Isoflurane Ketamine Rapid redistribution PDE-5 Dobutamine Betaxolol Atenolol NRTI E1 F2alpha Mivacurium Ketamine Valproic acid Well absorbed orally Inhibits DNA gyrase Pracainamide/ Amiodarone Sodium nitroprusside Acts on RyR1 receptors resulting in decreased calcium Methicillin Dapsone Cycloserine Rifampicin Gastro-Intestinal toxicity H K ATPase inhibition Decrease in bone matrix proteins Subcutaneous/ IM Adrenaline
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drkamalkvs classes: FMGE, DNB & Pre-PG putting Foreign Medical Graduates first
Next week: ENT, dermatology & Microbiology

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