Pathology cell injury and adaptation MCQ 1 Irreversible cell injury is associated with a) Clumping of chromatin b) ndoplasmic swelling

g c) !educed o"idative phosphorylation d) Profound membrane disturbance e) #atty change %ystrophic calcification a) &ccurs in normal tissues b) Is associated with hypercalcaemia c) Is seen in vitamin % related disease d) &ccurs in atheromatous disease e) May be a part of the mil' al'ali syndrome !egarding metastatic calcification which statement is incorrect a) )ffects 'idneys and lungs more than the liver b) Is seen in organs that have a relatively al'aline compartment c) Is initiated in the mitochondria d) &ccurs in normal tissues e) Is often seen in the pulmonary veins !egarding hyperplasia which statement is correct a) It is never seen in the same tissue as hypertrophy b) it is seen in cardiac muscle in hypo"ic patients c) it is limited to cells capable of mitotic division d) it is rarely physiologic e) complete removal of e"cess hormone triggers will slow progression but not reverse hyperplastic changes ischaemic injury a) May be caused by any state of reduced o"ygen delivery b) Is associated with an efflu" of calcium and sodium c) ,eads to redued glycolycis in the cell d) ,eads to cessation of cardiac muscle contraction in appro" 1+ minutes of coronary occlusion e) -sually results in a necrotic pattern of injury

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