DATE OF BIRTH: 03-09-1963 NATIONAL I.CARD: 36302-5841104-1 PASSPORT #: FL 5141042 Date of Issue: 21 Dec, 2011 REGISTRATION # : 843-A/89. Punjab Pharmacy Council (Pakistan) MARITAL STATUS: Married RESIDENCE: C-13 Staff Colony, BZ University, Multan. Mob: +92-322-6151040 Off. +92-61-9210071 (Ext.2605) PRESENT: 4A Saint-peitersonplain 16, Gent 9000, Belgium Mob: 0492245090, Off. +32 9264 8101 E-mail: nisarhussain@bzu.edu.pk : nisar.hussain@ugent.be ACADEMIC QUALIFICATIONS: Post-Doc Fellowship July,2012 to onward for nine months at (DruQuaR), UGent, Belgium. Ph. D. 2011 Topic: "Percutaneous absorption of analgesic in the presence of In Pharmacy Permeation enhancers MBA Marketing 1 st Div AIOU 2004 M. Phil. Pharmaceutics 1 st .Div 585/900 1992 B. Pharmacy Pharmacy 1 st .Div 2182/3600 1987 F. Sc. Pre-medical 1 st .Div 634/1000 1982 Matric Science Group 1 st .Div 663/850 1979 FIELD OF RESEARCH AND STUDY Preformulation and Drug development, Biopharmaceutics and TDDS EXPERIENCE a) Professional Experience: Designation Department / Organization Scale / Grade Duration Responsibility From To Pharmaceutical Analyst Life Pharma, Multan Rs.3000/= Oct,1987 Jan,1995 Analysis of Raw and finished products b) Teaching Experience: Designation Department / Organization Scale / Grade Duration Responsibility From To Associate Professor in Pharmacy Hazara University, Mansara (KPK) BPS-20 Oct,2011 Dec,2011 Teaching , research and administration Assistant Professor in Pharmaceutics Bahauddin Zakariya University,Multan BPS-19 Sep,2002 To-date Teaching and research Lecturer in Pharmaceutics Bahauddin Zakariya University,Multan BPS-17 Jan,1995 Sep,2002 Teaching and research Research Officer/ Part- Time Bahauddin Zakariya University,Multan Rs.4000/= Oct,1992 Jan,1995 Teaching and research Demonstrator Bahauddin Zakariya University,Multan Rs.1200/= Oct,1987 Jan,1989 Teaching and research TRAINING AND PROFESSIONAL SKILL Certificate of Service (NCC) (1979-81) Certificate of Internship (Nishtar Hospital & MINAR, Multan) 1987 Certificate courses in Computer DOS & BASIC and Fox-Pro.(1992) Ist. Pharmacy Training Workshop in Gomal University, DI Khan by HEC; 2001 Staff Development under the Scheme National Academy of Higher Education by HEC; May 2005 HEC foreign scholarship under scheme IRSIP for year 2008 and worked in School of Pharmacy, University of London, UK for six months (March-August,2008) HEC foreign scholarship under scheme Post-Doc Fellowship (Batch-V) for year 2012 and working in Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Drug Analysis (DruQuaR) group, University of Ghent, Belgium for nine months (from July, 2012). REVIEWER OF JOURNALS 1. International Journal of Pharmaceutics 2. Drug development and Industrial Pharmacy 3. AAPS Journals 4. OMJ (Oman) 5. Journal of Applied Research (JAR) 6. Journal of Research (Science) B.Z. University, Multan 7. Journal of Research, Gomal University, DIKhan 8. Editor, Jour. of Res. (Sci) B.Z. University, Multan (2012) 9. Member editorial board, Pak. J Pharmacy, PU, Lahore (2011) 10. Many others LIST OF M.PHIL THESIS CO-SUPERVISED 1. Interfacial Behavior of locally available Gums, 1992 2. Comparative Bioavailability and Pharmacokinetic of Cefradin available in local market in healthy human volunteers,1993 3. Study of Microbial Resistance Bacteria Isolated from Milk Products, 1994 4. In-Vitro evaluation of some commercially available brands of Rifampacin Tablets, 1999. 5. Effect of different concentrations of Honey as binder on the dissolution behavior of Mefenamic acid tablets 2000. 6. Effect of vehicles on topical absorption of Diclofenac through Rabbit skin 2000 7. Study of Bactericidal Activity of different Soaps against gram-positive and gram- negative bacteria, 2002. LIST OF M.PHIL THESIS SUPERVISED 1. Dissolution rate study for the evaluation of release rate characteristics of binders in tablets.2005 2. Enhancing effect of essential oils on the percutaneous absorption of Diclofenac through hairless rabbit skin,2005 3. Study to design coated granules of Dihydroartemisinin(DHA) and formulation of dry suspension using various coating materials.(2006) 4. Formulation and optimization of natural gums based sustained release matrix tablets of flurbiprofen(2007) 5. Formulation and comparative in vitro and in vivo evaluation of hydrophilic matrix tablets for sustained release of diclofenac sodium (2007) 6. Permeation enhancement studies of physical mixtures of artemisinin in polyvinylpyrrolidone (2008) 7. Comparative evaluation of Trop-T and other cardiac enzymes in MI patients and cardiac managed care (2008) 8. Transdermal absorption of solid dispersion and lyophilized mixture of ART in the presence of PVP (2009) 9. Transdermal absorption of solid dispersion and lyophilized mixture of ART in the presence of different polymers (2009). 10. Formulation and permeation kinetics studies of Nimesulide lotion through rabbit skin (2010). 11. Permeation enhancement studies of solid dispersion and lyophilized mixture of Artemisinin in PVP and PEG binary system (2010). 12. Formulation and Permeation kinetics of Lornoxicam lotion using RSM (2011) 13. Formulation and permeation kinetics of flurbiprofen lotion using response surface methodology (2011) 14. The rational use of drugs in TB patients with special emphasis on side effects (2011) 15. Formulation and Permeation kinetics of Escitalopram Oxalate lotion (2011) 16. Formulation and Permeation kinetics of 2-Phenoxy 2-Methyl Propionic acid lotion (2011) 17. Biological effects of Zinc chelators in PC 12 Cells (2011) LIST OF M.PHIL THESIS PRESENTLY SUPERVISING Nine (9) M.Phil research students have been allocated and completed their research work and started writing their thesis for session 2012. The topics are as follows 1. A statistical approach-Formulation and permeation kinetic studies of Flurbiprofen Gel. 2. Formulation, development and evaluation of Chlorphenaramine maleate Gel. 3. Gel formulation and characterization of Cefixime and Chlorphenaramine maleate. 4. Topical Citrizine HCl Gel and its permeation kinetic studies. 5. Formulation development and permeation kinetic studies of Citrizine HCl and Neomycin Sulfate Gel. 6. Formulation and release rate characteristics evaluation of Metoclopramide HCl Gel. 7. Optimization of formulated Gel and evaluation of permeation kinetics. 8. Formulation, optimization and permeation kinetic studies of Diclofenac Gel. 9. Application of Response Surface Methodology in optimization and evaluation of Muscular Spasmatic Gel LIST OF PUBLISHED ARTICLES 1. Mehboob-E-Rabbani, Azhar Jamal Saleemi, Syed Nisar Hussain Shah, Kalsoom Farzana and Bashir Ahmad. "Comparative Bioavailability and Pharmacokinetic of Cefradin available in local market in healthy human volunteers", Pak. J. Pharmacy, Punjab University Lahore, pp:19-27, 1994. 2. Mehboob-E-Rabbani, Syed Nisar Hussain Shah, M Ahmad and AM Durani, Comparative bioavailability and Pharmacokinetics of Ampicilline syrup in healthy human volunteers, Pak. J. of Pharmacy, Punjab University Lahore, 9(2), pp:43-49, 1996. 3. Kalsoom Farzana, Syed Nisar Hussain Shah and Farzana Jabeen. Antibiotics resistance pattern against various isolates of Staphylococcus aureus from raw milk samples, Jour. of Res.(Sci), 15(2),pp:145-151, 2004. 4. Kalsoom Farzana, Syed Nisar Hussain Shah, Farooq Bashir and Sattar Bukhsh. "Biosynthesis of Bacitracin in Stirred fermenter by Bacillus licheniformis using defatted oil seed cakes as substrate", Jour. of Res.(Sci), 15(3),pp:285-290, 2004. 5. Kalsoom Farzana, Shazia Batool, Syed Nisar Hussain Shah, and Farzana Jabeen. Study of Bactericidal activity of different soaps against Salmonella Typhi, Jour. of Res.(Sci.),15,4, pp:361-368, 2004. 6. Kalsoom Farzana, Syed Nisar Hussain Shah, Shazia Batool and Farzana Jabeen. Antibiotic resistance pattern against various isolates of Staphylococcus aureus from milk products Khoya and burfi, Jour. of Res.(Sci.),15,4, pp:419-427, 2004. 7. Kalsoom Farzana, Syed Nisar Hussain Shah, Farooq Bashir and Sattar Bukhsh "Biosynthesis of Bacitracin in Solid-State fermentation by Bacillus licheniformis using defatted oil seed cakes as substrate", Pak J of Pharmaceutical Sci.,18(1) pp:55-57, Jan. 2005. (I F 1.103) 8. Syed Nisar Hussain Shah, ME Rabbani and Amir MF, In vitro study of percutaneous absorption of diclofenac in the presence of SLS through hairless rabbit skin, J.of Res. (Sci.), 16, 1, pp: 45-50, June 2005. 9. Kalsoom Farzana, Farzana Jabeen and Syed Nisar Hussain Shah. "Antibiotic Resistance pattern among gram-negative bacteria isolated from raw milk in Multan". Pak. J. Pharm. Sci., 18, 3, pp: 11-16, July 2005. (I F 1.103) 10. Syed Nisar Hussain Shah, Muhammad Salman, Mashhood Ahmad, Yasser Shahzad, Sajid Asghar and Asma Safdar; Effect of essential oils on the percutaneous absorption of Diclofenac diethylamine; Pak. J. Pharm., Punjab University Lahore, 16-20 (1&2), 2003-6. 11. Syed Nisar Hussain Shah, Muhammad Fakhruddin Amir, Mahboob Rabbani, Asma Safdar, Yaseer Shahzad, Romana Riaz and Amir Badshah, Percutaneous absorption of diclofenac diethylamine in the presence of dimethyl sulfoxide, Pak. J. Pharm., Punjab University Lahore, Pak. J. Pharm. 20-23 (1 & 2), 31-35, 2007-2010. 12. Syed Nisar Hussain Shah, ME Rabbani and Amir MF, Study of Percutaneous absorption of diclofenac Diethylamine in the presence of Cetrimide through hairless rabbit skin, J.of Res. (Sci.), 17, 1, pp-45-51, Jan.2006. 13. Kalsoom Farzana, Shazia Batool, Syed Nisar Hussain Shah, Malik Sattar Bukhsh and Farzana Jabeen. Bactericidal activity of different soaps against Staphylococcus aureus, Gomal University Jour. of Res.,22,(1),pp:11-16,June 2006. 14. Malik Sattar Bukhsh, Muhammad Ramzan, Gul Majid Khan, Kalsoom Farzana and Syed Nisar Hussain Shah, In-vitro study of various antimicrobial agents against urinary tract isolates, Gomal University Jour. of Res.,22,(1),pp:28-32 ,June 2006 . 15. Syed Nisar Hussain Shah, ME Rabbani and Amir MF, Effect of Urea on topical absorption of diclofenac Diethylamine through hairless rabbit skin, J.of Res. (Sci.), 17, 3, pp-165-171, July, 2006. 16. Kalsoom Farzana, Syed Nisar Hussain Shah, Farooq Bashir and Jamshaid Ali Khan, "Effect of partial replacement of different defatted oil seed cakes as substrate in biosynthesis of bacitracin in solid-state fermentation by Bacillus licheniformis ", Pak J of Pharmaceutical Sci.,20(3) pp:227-230, July, 2007. (I F 1.103) 17. Syed Nisar Hussain Shah, Mahboob Rabbani, Kashif Mahmood and Muhammad Tahir Razi and Muhammad Uzair, Comparative Evaluation of Some Commercially Available Brands of Rifampacin Tablets J.Sci.Res. University of Punjab, XXXIX 1, 21-28; June, 2009. 18. Syed Nisar Hussain Shah, Sajid Asghar, Sajid Akash, Nisar ru Rehman and Sattar Bukhsh, Formulation and optimization of natural gums based sustained release matrix tablets of flurbiprofen, Drug Devel. & Industrial Pharmacy, 35(12): 14701478, 2009. (I F 1.494) 19. Muhammad Tayyab Ansari , Shahid Karim , Nazar Muhammad Ranjha , Syed Nisar Hussain Shah , and Sher Muhammad, Physicochemical characterization of artemether solid dispersions with hydrophilic carriers by freeze dried and melt methods, Arch Pharm Res 33( 6), 901-910, 2010. (I F 1.592) 20. Muhammad Sajid Hamid Akash , Ikram Ullah Khan , Syed Nisar Hussain Shah , Sajid Asghar , Asif Massud , Muhammad Imran Qadir and Atif Akbar, Sustained release hydrophilic matrices based on xanthan gum and hydroxypropyl methylcellulose: development, optimization, in vitro and in vivo evaluation, J App Pharm 4 (2) : 89-103, 2010. (I F 0.16) 21. Syed Nisar Hussain Shah, Yaseer Shahzad, Shabbar Atique, Muhammad Tayyab Ansari and Farooq Bashir, The evaluation of a novel strategy to mask the bitter taste of dihydroartimisinin granules, Braz.J.Pharm.Sci. 47, 2, 1-8, 2011. (I F 0.276) 22. Farooq Bashir Butt, Syed Nisar Hussain Shah and Muhammad Tayyab, General misconceptions about medication, Pak. J. Pharm., Punjab University Lahore, 24,55-56 (1&2), 2011. 23. Amir Badshah, Fazal Subhan, Syed Nisar Hussain Shah, Nadeem Irfan Bukhari, Muhammad Saeed and Kifayat Shah, Once daily controlled released Matrix tablet of Prochlorperazine maleate: Influence of Ethocel and Methocel on in-vitro drug release and bioavailability. Drug Development and Industrial Pharmacy, 38, 2, 190199, 2012. (I F 1.494) 24. Syed Nisar Hussain Shah, Muhammad Salman, Mahboob Rabbani and Amir Badshah,Effect of oleic acid on the permeation kinetics of diclofenac diethylamine J Chem Society Pak, 34,1, Feb,2012. (I F 1.377) 25. Bushra Nasir, Syed Nisar Hussain Shah, Ghulam Murtaza, Niriman Shahid, Muhammad Akhtar, BA Khan3, Sira Azhar, Asma Mumtaz, A Waseem, SA Khan, Muhammad Ubaid, S Noreen, B kamal, MHHB Asad, New HPLC method for the determination of artemether in injections, Scientific Research and Essays, 7,10, 1165-1168, 16 March, 2012. (I F 0.17) 26. Yasser Shahzad * ; Syed Nisar Hussain Shah; Muhammad Tayyab Ansari; Romana Riaz; Aasma Safdar; Talib Hussain and Madeeha Malik, Drug-Polymer complexation: effect on solubility and in vitro diffusion of Artemisinin across polydimethylsiloxane membrane, Chinese Science Bulletin. 57,14,1685, May,2012. (I F 1.321) 27. Atif Raza Sial , Muhammad Fawad Rasool, Syed Nisar Hussain Shah,Nazar Muhammad Ranjha & Ghulam Murtaza, Effect of Different Hydrophillic Binders on the Dissolution Profiles of Mefenamic Acid, Lat. Am. J. Pharm. 31,3, 2012. (I F 0.288) 28. Syed Nisar Hussain Shah, Mahboob Rabbani, Yaseer Shahzad, Amir Badshah, Victtor M. Meidan and Ghulam Murtaza, Developing an efficacious diclofenac diethylamine transdermal formulation Jour. Food Drug Analysis, 20, 2 , 464-471, 2012. (I F 0.643) 29. Rao A. HAMEED, Mehboob-e-RABBANI, Syed Nisar Hussain SHAH, Shujaat A. KHAN, Muhammad A. YAMEEN, Muhammad H.H.B. ASAD, Ghulam MURTAZA, Adsorption Studies of Non-Ionic Surfactants at Different Vegetable Oil-Water Interfaces, Lat. Am. J. Pharm. 31 (6): 864-8 (2012) (I F 0.288) 30. Syed Nisar Hussain Shah, Yasser Shahzad
, Muhammad Tayyab Ansari, Muhammad Haneef
, Madeeha Malik, Gulam Mrtaza an Amir Badshah , Permeation kinetic Studies of Physical Mixtures of Artemisinin in Polyvinylpyrrolidone, Dissulotion Technologies, (accepted) August 22, 2011. (I F 0.69) 31. Syed Nisar Hussain Shah,Muhammad Azam Tahir and Ghulam Murtaza, "Effect of permeation enhancers on the release behavior and permeation kinetics of novel tramadol lotions, Tropical Journal of Pharmaceutical Research, (accepted) June,2012. (I F 0.82) 32. Syed Nisar Hussain Shah, Muhammad Fakhar and Ghulam Murtaza, Effect of Garlic Extract on Blood Glucose Level and Lipid Profile in Normal and Alloxan Diabetic Rabbits, Advances in Clinical and Experimental Medicines, (accepted), 2011.(I F 0.176) 33. Yasser Shahzad , Syed Nisar Hussain Shah, Arooj Ambreen, Muhammad Talib, Madeeha Malik, Applying response surface methodology to optimize nimesulide permeation from topical formulation. Pharmaceutical Development and Technology (LPDT-2012-0216; accepted).(I F 1.363) 34. Yaseer Shahzad, Syed Nisar Hussain Shah, Mahboob Rabbani, Amir Badshah and Victtor M. Meidan, A new diclofenac diehtylamine topical formulation: in vitro and in vivo evaluation. Farmacia (submitted on 28 February 2012) Under review. (I F 0.669) 35. Yasser Shahzad , Syed Nisar Hussain Shah, Qalander Khan, Muhammad Talib, Madeeha Malik, Development and Optimization of Topically Applied Lornoxicam Transdermal Formulation using Box-Wilson Statistical Design. Drug Development and Industrial Pharmacey (LDDI-2012-0400) Under review. (I F 1.494) 36. Muhammad Sajid Hamid Akash, Syed Nisar Hussain Shah, Musa Raza, Kanwal Rehman, Furqan Iqbal and Shuqing Chen, Characterization of ethyl cellulose and hydroxypropyl methylcelluse microspheres for controlled release of flurbiprofen using response surface methodology, Journal of Materials Science: Materials in Medicine(submitted and under review, July 2012). (I F 2.015) LIST OF PUBLISHED ARTICLES AS PROCEEDINGS, ABSTRACT 1. ME Rabbani, Syed Nisar Hussain Shah, A Rasheed, I Tahir and M Ahmad, Comparative bioavailability and pharmacokinetics of Erythromycin ethylsuccinate suspension in healthy human volunteers. Proceeding, All Pakistan Science Conf. 16-21 May,1992, pp: 79-81. 2. ME Rabbani, I Tahir and Syed Nisar Hussain Shah, Interfacial Behavior of Gum Tragacanth locally available. Proceeding, All Pakistan Science Conference 16-21 May, 1992, pp: 50-52. 3. Kalsoom Farzana and Syed Nisar Hussain Shah, "Antibacterial activity of coagulase-positive Staphylococci isolated from milk", Proceeding, All Pakistan Science Conference, 26-30 December, 1993, pp: 231. (Abstract). 4. Kalsoom Farzana, Syed Nisar Hussain Shah. "In-vitro buffering Capacity of various Silicone Bound Antacids", Proceeding, All Pakistan Science Conference, 26-30 Dec.1993, pp: 231. (Abstract). 5. Syed Nisar Hussain Shah, Pharmacy in a new age, Proceding, 3 rd National Conference on Pharmaceutical Sciences, Uni. of Peshawar at Baragali, p-19 July, 2003.
CONFERENCES, SEMINARS AND WORKSHOPS PARTICIPAT 1. 35 th Information Systems Research Seminar in Scandinavia (IRIS- 2012) August 1720, 2012, Sweden. 2. 17 th IPCE 2012, Marriat Islamabad ;organized by PPA; 19 th April to 21 st April 2012. 3. 16 th IPCE 2011, PC Lahore ;organized by PPA; 28 th April to 1 st May 2011. 4. 1 st National Seminar on use of Animals in Science Ethical and Practical Consideration University of The Punjab Lahore, January 3-4, 2011. 5. 11 th Annual Population Research Conference Population Growth, Urbanization, Poverty and Social Exclusion, B.Z. University Multan, 25-27 November, 2010. 6. 9 Th SKIN FORUM ;School of Pharmacy, University of London, UK ; 25-26 June,2008 7. 4 th National Pharmacy workshop Peshawar University Summer Camp Baragali, August 27-31, 2007. 8. 1 st National Pharmacy Conference Better Quality of life through Pharmacy Profession Islamia University of Bahawalpur on 2-4 March 2007. 9. 6 th International & 16 th National Chemistry Conference Quality of life and chemistry Sciences B.Z. University Multan on 6-8 th April 2006. 10. Seminar on Opportunities Under WTO for Pharmaceutical Sector of Pakistan at Lahore College for Women University, Lahore on 15 th December,2005. 11. 12 th International Pharmacy Conference Pearl Continental Karachi on 18-21 st February 2004 12. 3 rd National Conference on Pharmaceutical Sciences, Peshawar University Summer Camp Baragali, 19-23 July 2003. 13. National Seminar on GMP , GSP & GLP organized by Ministry of Health in collaboration with WHO at Al-Hamra Arts Council Lahore on 23-24 th December 2002. 14. 2 nd DIA International Congress and 16 th National Pharmacy Conference in Lahore, 9 th
12 th January 2001. 15. Symposium on Unani Medicine: Expanding Medical Horizon at Holiday Inn, Multan, 27 th October, 2001. 16. Workshop on Total Quality Management, organized by Ministry of Health and WHO at Sherton, Karachi, on 12-14, November,2001. 17. International Workshop on Total Quality Management of Drugs, organized by Ministry of Health and WHO at Islamabad on December 3-5, 1999. 18. Seminar and Workshop on Rational use of Drugs, Lahore December 1999. 19. International Pharmaceutical Congress and Exhibition, Lahore 20 th 23 rd March 1998. 20. 14 th Asian Congress of Pharmaceutical Sciences, Lahore November 5 th 9 th 1996. 21. WHO/MOH Workshop; Development of Pharmaceutical Services in Pakistan Lahore, December 17 th 19 th 1995. 22. 3 rd All Pakistan Science Conference, at Baragali September 11 th 15 th 1994. 23. 2 nd All Pakistan Science Conference, at Lahore December 26 th 30 th 1993. 24. 1 st All Pakistan Science Conference, at Khanspur May 16 th 21 st 1992. 25. 6 th International Pharmacy Conference, Holiday Inn, Islamabad on 18-21th December 1986. Books Written: Sustained Release Tablets - Matrix Based Sustained Release Formulation of Diclofenac Sodium; Published by LAMBART Academic Publishing (LAP) GmbH & Co, Germany (2010). Popular Articles: Formulation and optimization of natural gums based sustained release matrix tablets of flurbiprofen, Drug Devel. & Industrial Pharmacy, 35(12): 14701478, 2009 MEMBERSHIP OF LEARNED ORGANIZATIO0NS 1. Member, Pakistan Pharmacist Association since 1986 2. Registered Pharmacist, Pharmacy Council of Pakistan since1987 3. Member, Academic Staff Association BZU Multan since 1995 4. Member, Lions International since 1996 5. Member, District Quality Control Board , Multan, Govt. of Punjab; 2004-8 6. Member SENNAT, Bahauddin Zakariya University Multan, 2007-2010