SPECIFIC GUIDELINES FOR CONTROLLING WORKPLACE EXPOSURES AT UC IRVINE ANIMAL
SURGERY LOCATIONS A. INTRODUCTION Waste anesthetic gases (WAG) are unused anesthetics that have a potential to unintentionall e!pose researchers i" not properl controlled. #!posure to $aste anesthetic gases (WAG) causes %oth short and long&ter' health e""ects as descri%ed in anesthetic speci"ic (aterial )a"et Data )heets (()D)). I" ou %elieve occupational e!posure to $aste anesthetic gases is occurring* or $ould li+e an evaluation o" our WAG control set&up* please contact ca'pus #,-) "or assistance* ./0&1/22. This docu'ent provides guidance "or controlling $or+place e!posure to WAG in veterinar settings using engineering and $or+ practices. )ee General Wor+place Controls "or additional in"or'ation as $ell as ad'inistrative controls that appl to controlling WAG. These guidelines are not a ne$ standard or regulation. The are advisor in nature* in"or'ational in content* and intended "or use % e'ploees to provide a sa"e and health"ul ani'al research environ'ent. The guidelines are not 'eant to co'pro'ise sa"e anesthetic practices that protect research su%3ects. 4. )OURC#) O5 WA)T# AN#)T,#TIC GA)#) (WAG) 6. 7ea+s "ro' gas suppl lines and connections. /. 7ea+s $ithin the anesthesia 'achine and %reathing )ste'. 8. 7ea+s %et$een su%3ect and "ace'as+. 0. 7ea+s "ro' around the tracheal tu%ing. 9. )pills o" li:uid anesthetics. C. ;#T#RINAR< )=#CI5IC WOR>=7AC# CONTRO7) This section descri%es engineering and $or+ practice controls speci"ic to veterinar clinics and hospitals. #ngineering and $or+ practices suita%le "or other environ'ents $here anesthetics are ad'inistered are provided in )ection 5 o" the O),A Waste Anesthetic )a"et and ,ealth Topic docu'ent. Inhalation anesthesia in veterinar hospitals is practiced in a 'anner si'ilar to that in hu'an hospitals. Generall* ani'als are initiall given an in3ecta%le anesthetic* "ollo$ed % general anesthesia 'aintained % an inhalation techni:ue. In ani'al anesthesia* there are "ive %asic 'ethods % $hich inhalation anesthetics are ad'inistered? open&insu""lation* se'iopen $ithout nonre%reathing valves* se'iopen $ith nonre%reathing valves* se'iclosed* and closed. 5igure 6 illustrates a circle %reathing sste'. O!gen and anesthetic are transported to the ani'al@s lungs "ro' the anesthesia 'achine through a "ace 'as+ or tracheal tu%e. An in"lata%le cu"" on the distal end o" the tracheal tu%e "acilitates a seal $ith the inner $all o" the trachea. A. O!gen source 5. <&=iece connecting inspirator 4. =ressure reducing valve And e!pirator hoses C. 5lo$ 'eter G. #!pirator valve D. ;aporiAer ,. Reservoir %ag #. Inspirator valve I. Car%on dio!ide a%sor%er B. =op&o"" valve 5igure 6. Circle %reathing sste' used "or veterinar anesthesia. (Reproduced % per'ission o" A'erican Industrial ,giene Association* 5air"a!* ;irginia). Unidirectional valves allo$ "lo$ "ro' the vaporiAer to the ani'al upon inspiration and route the e!haled gases through a car%on dio!ide a%sor%er during e!piration. ,igh "resh&gas "lo$s are tpicall used $ith all techni:ues e!cept closed&sste' %reathing circuits. During e!piration* e!cess or $aste gas e!its the %reathing circuit at the ad3usta%le pressure&li'iting (A=7) or pop&o"" valve and escapes into the roo' unless it is appropriatel scavenged. Controlled re%reathing sste's used "or ver s'all ani'als allo$ e!haled gases to %e i''ediatel e!pelled "ro' the sste' into the roo' air. 4ecause these sste's do not include a car%on dio!ide a%sor%er* greater "resh&gas "lo$s are re:uired to ensure re'oval o" car%on dio!ide "ro' the sste'. A higher "resh&gas "lo$ 'a lead to an increase in a'%ient $aste gas levels. 6. #ngineering Controls =lacing the surgical "ield inside a chemical !me h""# is argua%l the easiest 'ethod to control e!posure to $aste anesthetic gases. ,o$ever* this approach is not al$as "easi%le* and scavenging and $aste gas disposal sste's 'ust %e put into place. The %asic principles o" scavenging used to capture e!cess anesthetic gases in hospital surgical suites are appropriate "or application in veterinar anesthesia. ()ee )cavenging )ste's "or ela%oration on these sste's.) A scavenging nasal 'as+ consists o" a co'pact dou%le 'as+ sste'. It 'ust consist o" a shroud large enough to capture e!haustedCescaping nitrous o!ide e!iting "ro' a 'outh. An inner 'as+ is contained $ithin a slightl larger outer 'as+ and a slight vacuu' is present in the space %et$een the 'as+s. The ad3usta%le pressure&li'iting valve (A=7) or pop&o"" valve is connected to the scavenging inter"ace valve. A $aste gas reservoir %ag is attached to the inter"ace valve and collects e!cess anesthetic gases. In general* the "inal disposal point "or volatile WAG generated in a veterinar "acilit can %e an one o" the "ollo$ing? Tu%ing placed inside single&pass (non&recirculating) ventilation sste'D Tu%ing "ro' vacuu' sste' e!hausted to a single&pass (non&recirculating) ventilation sste'D dedicated %lo$er Ee!haustF sste' installed over anesthesia "ieldD "or halogenated co'pounds* disposal tu%ing connected to adsor%er trap. )ee #!haust (ethods "or 'ore ela%oration. A vacuu' source* i" present* is connected to the inter"ace valve and $aste gas reservoir %ag* $here gas is stored until the vacuu' can 'ove it to the outside air. The vacuu' scavenges gases e!haled as $ell as an e!cess gas "ro' the anesthesia 'achine that could lea+ "ro' around the edges o" the inner and outer 'as+s. I" onl halogenated co'pounds are used* an activated charcoal adsorption sste' can %e used. /. Wor+ =ractices The "ollo$ing are reco''ended $or+ practices "or reducing gas lea+age? =er"or' a sste' chec+out prior to use. Re"er to the 6GG8 5ood and Drug Ad'inistration (5DA) Anesthesia Apparatus Chec+out Reco''endations docu'ent "or ideas on developing one suita%le "or our e:uip'ent. (a+e sure that $aste gas disposal lines are connected. Avoid turning on N/O or a vaporiAer until the circuit is connected to the ani'al. )$itch o"" the N/O and vaporiAer $hen not in use. (aintain o!gen "lo$ until the scavenging sste' is "lushed. )elect the opti'al siAe tracheal tu%e "or the ani'al and 'a+e sure the cu""* i" present* is ade:uatel in"lated. Delivering a positive&pressure %reath $hile the A=7 or pop&o"" valve is closed and listening "or a lea+ originating "ro' around the tracheal tu%e cu"" 'a evaluate ade:uac o" cu"" in"lation. Occlude the <&piece i" the %reathing circuit 'ust %e disconnected during surger. Once anesthesia is discontinued* e'pt the %reathing %ag into the scavenging sste' rather than into the roo'. Releasing anesthetic gases into the OR could signi"icantl increase the overall $aste gas concentration $ithin the roo'. At the end o" the surgical procedure* continue to ad'inister non&anesthetic gasesCagents as long as clinicall necessar* using high o!gen "lo$ rates through the %reathing circuit to $ash the anesthetic gases out o" the sste' and the ani'al. This allo$s e!haled anesthetic gases to %e collected % the scavenging sste'. It is possi%le to close an anesthetic circle and reduce "resh&gas "lo$ rates. In a circle sste' $here o!gen is the onl carrier gas* the a'ount o" "resh gas "lo$ing to the ani'al should %e ad3usted to closel 'atch the ani'al@s 'eta%olic o!gen re:uire'ent. )elect 'as+s to suit various siAes and %reeds encountered in veterinar practice. When a 'as+ is used "or induction or 'aintenance o" anesthesia* use a 'as+ that properl "its the contour o" the ani'al@s "ace to 'ini'iAe gas lea+age. (ini'iAe the ti'e o" 'as+ anesthesia to reduce $aste. Use a %o! "or induction o" anesthesia in s'all* uncooperative ani'als. As $ith the 'as+ techni:ue* the induction %o! 'ethod re:uires high gas&"lo$ rates* $ith su%stantial anesthetic spillage. (ethods to 'ini'iAe this spillage include tight seals on the %o! and place'ent o" the %o! in a che'ical "u'e hood or near the ventilation port o" a $ell&ventilated roo'. The %o! can also %e connected to an anesthetic gas&scavenging sste' to evacuate the gases in the %o! prior to re'oving the ani'al. (a+e certain that the reservoir %ag* used to store e!cess anesthetic $aste gas until the vacuu' sste' can re'ove it* is ade:uate to contain all scavenged gas. This reservoir %ag is especiall designed to connect to anesthetic gas&speci"ic "ittings. D. C7#AN&U= AND DI)=O)A7 O5 7IHUID AN#)T,#TIC AG#NT )=I77) )'all volu'es o" li:uid anesthetic agents such as halothane* en"lurane* iso"lurane* des"lurane* and sevo"lurane evaporate readil at nor'al roo' te'peratures* and 'a dissipate %e"ore an atte'pts to clean up or collect the li:uid are initiated. Incidental releases o" li:uid anesthetic agents $here the su%stance can %e a%sor%ed* neutraliAed* or other$ise controlled at the ti'e o" release can %e per"or'ed % e'ploees in the i''ediate release area. ,o$ever* $hen large spills occur* such as $hen one or 'ore %ottles o" a li:uid agent %rea+* speci"ic cleaning and contain'ent procedures are necessar and appropriate disposal is re:uired. #vacuate the i''ediate area and contact #,-). 4ecause o" the volatilit o" li:uid anesthetics* rapid re'oval % suctioning is the pre"erred 'ethod "or cleaning up spills. I" a%sor%ed* the $aste 'aterial should %e placed in a container* tightl sealed* properl la%eled* and disposed o" $ith other che'ical $astes through #,-). The reco''endations o" the che'ical 'anu"acturer@s 'aterial sa"et data sheet (()D)) that identi" e!posure reduction techni:ues "or spills and e'ergencies should %e "ollo$ed. #'pt anesthetic %ottles are not considered regulated $aste and 'a %e discarded $ith ordinar trash or reccled. To 'ini'iAe e!posure to $aste li:uid anesthetic agents during clean&up and disposal* the "ollo$ing general guidelines are reco''ended % the 'anu"acturers o" li:uid anesthetic agents? Wear appropriate personal protective e:uip'ent as indicated on ()D). )ee )ection # o" General Wor+place Controls "or Waste Anesthetic Gases. Where possi%le* ventilate area o" spill or lea+. Appropriate respirators should %e $orn. Restrict persons not $earing protective e:uip'ent "ro' areas o" spills or lea+s until clean&up is co'plete. Collect the li:uid spilled and the a%sor%ent 'aterials used to contain a spill in a glass or plastic container. Tightl cap and seal the container and re'ove it "ro' the anesthetiAing location. 7a%el the container clearl to indicate its contents. Trans"er the sealed containers to the $aste disposal co'pan that handles and hauls $aste 'aterials. ,ealth&care "acilities that o$n or operate 'edical $aste incinerators 'a dispose o" $aste anesthetics % using an appropriate incineration 'ethod a"ter veri"ing that individual incineration operating per'its allo$ %urning o" anesthetic agents at each site. #. (AT#RIA7 )A5#T< DATA ),##T) (()D)) 5OR AN#)T,#TIC) Up&to&date (aterial )a"et Data )heets (()D)) "or anesthetics are availa%le at http?CC$$$.uc'sds.co'C. ()D)s provide in"or'ation on the haAard* e!posure control and e'ergenc procedures "or $or+ing $ith anesthetics. 5. OT,#R R#)OURC#) Control o" Waste Anesthetic Gases in the Wor+place* A'erican College o" ;eterinar Anesthesiologists. )a"et - ,ealth Topic? Waste Anesthetic Gases* O),A. Waste Anesthetic Gases* ;eteran@s Ad'inistration. Waste Anesthetic Gases* Canadian Centre "or Occupational ,ealth - )a"et. #!haust (ethods* UCI. General Wor+place Control (ethods "or Waste Anesthetic Gases* UCI. )cavenging )ste's* UCI. These safety training resources, prepared solely for the use of the Regents of the University of California, were provided by a variety of sources. It is your responsibility to customize the information to match your specific operations. Neither the University of California nor any of its employees, maes any warranty, e!press or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial product, process, or service by trade name, trademar, manufacturer, or otherwise, does not necessarily constitute or imply its endorsement, recommendation, or favoring by the University of California. The views and opinions of authors e!pressed herein do not necessarily state or reflect those of the University of California, and shall not be used for advertising or product endorsement purposes.