This document provides background information on genetic engineering and discusses some of the key issues. It begins with a brief history of genetic engineering and biotechnology, noting that while artificial selection of plants and animals has occurred for thousands of years, the term "genetic engineering" was coined in the mid-20th century. It then explores the science behind genetic engineering and discusses some controversial figures and companies in the field, such as Genentech, Ian Wilmut, and the "Big Six" agricultural biotechnology firms.
This document provides background information on genetic engineering and discusses some of the key issues. It begins with a brief history of genetic engineering and biotechnology, noting that while artificial selection of plants and animals has occurred for thousands of years, the term "genetic engineering" was coined in the mid-20th century. It then explores the science behind genetic engineering and discusses some controversial figures and companies in the field, such as Genentech, Ian Wilmut, and the "Big Six" agricultural biotechnology firms.
This document provides background information on genetic engineering and discusses some of the key issues. It begins with a brief history of genetic engineering and biotechnology, noting that while artificial selection of plants and animals has occurred for thousands of years, the term "genetic engineering" was coined in the mid-20th century. It then explores the science behind genetic engineering and discusses some controversial figures and companies in the field, such as Genentech, Ian Wilmut, and the "Big Six" agricultural biotechnology firms.
The controversies around biotechnology and genetic engineering form a highly complex and tension filled dialogue in which the often harsh and impetuously clashing opinions can only be analyzed when the different arguments are clearly differentiated and associated with each other. Reflected in this dialogue are central issues of technology, the connection between human, society and nature and the relationship between science and ethics. The assessment of genetic engineering is therefore a cross-cutting issue that requires both natural and social science expertise. The public should be especially aware since the research and application of genetic engineering is not confined to the space of a laboratory; ultimately everyone has to live with the positive and negative consequences of this technology. Because of this background, it is understandable that in the debate about genetic engineering not only conflicts of interest are dealt with but also conviction conflicts about a sustainable technology and society. The debate is not only of theoretical relevance, but stands in the middle of context of a push in genetic research triggered by the progressive development of genetic engineering in agriculture and food.
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A Brief History Traditional biotechnology has a long history. Domestication of animals and plants can be traced back as far as 10,000 BC [1]. The first animal to be artificially bred is believed to be the dog. Scientists have found fossil evidence in Mesopotamia and Canaan dating to about 10,000 to 9,000 BC, where dogs were used as guard & work animals before they became popular pets [1]. Within the next 4,000 years several other species, such as cats, sheep, goats, chicken and wheat were domesticated. Many more plants were cultivated for the next millennia and by 2,000 BC the Sumerians were able to brew over 19 different types of beers [1]. It is important to understand that genetic modification has started much earlier than it is generally realized. For more than 12,000 years, the human has artificially selected and bred animals and plants. However, it was not until the mid-1900s that the term genetic engineering was first used. The innovation of computers brought about a genetic revolution which promised to improve humanity the same way computers improved information. In 1973, which is generally seen as the birth year of modern day genetic engineering, the two biochemists Stanley Cohen and Herbert Boyer created the first genetically modified organism (GMO) [2]. Since then, there have been many genetic engineering projects, from insulin producing bacteria to herbicide resistant tobacco, however, none of them has been as big as the Human Genome Project (HGP). The purpose of the HGP was to map the entire human genetic code. It was successfully completed in April 2003. One question still remains, what exactly is genetic engineering? According to Dr. Dean, a University Distinguished Professor in Biochemistry at Virginia Tech, genetic engineering represents the modification of the DNA of an organism such that it produces a new product not 3
normally produced by that organism, a modified form of a naturally produced product that has some added values, or a higher or lower level of a naturally produced product [3]. One thing to note is that artificial selection, as it started, has three very important differences compared to genetic engineering today. First, although different species were crossed with one another during early domestication, they were always closely related. This is drastically different in modern genetic engineering where genes of humans can be put into animals and genes of bacteria/viruses into plants. Secondly, the change in the genetic formula occurred at a much slower rate during early domestication. While the time scale of traditional biotechnology works on a time scale of years, genetic engineering nowadays only takes weeks. Thirdly, the number of species that were affected by domestication is relatively small as compared to the number of species that can be targeted by genetic engineering. Traditional biotechnology is mainly used to alter species that provide us with food, such as animals and plants. Genetic engineering goes as far as to change the genetic composition of humans. With the push in genetic research in the mid-1900s came many fears and moral objections to the technology. Despite the promise of this new knowledge, many showed and still show negative reactions to the idea of humans being bred like animals. While some of these moral objections are based on factual grounds, others are unfounded. Before we discuss these moral implications, we will briefly look at the science behind genetic engineering.
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The Science Behind Genetic Engineering To summarize, according to Dr. Dean, genetic engineering represents the modification of the DNA. DNA stands for Deoxyribonucleic acid and can be described as the molecule with the code of life [4]. Wrapped in its double helix structure are the genetic instructions for the development of any known living organism. DNA is based on a repeated pattern of a backbone made of sugar groups (deoxyribose) and phosphate groups with nitrogenous bases (nucleobases) attached to the sugars. The primary nucleobases are cytosine (C), guanine (G), adenine (A) and thymine (T) [4]. Depending on the combination of the nucleobases, there are three billion different base pairs. Arranged in different sequences, the three billion base pairs result in approximately 25,000 different genes [5]. While many of the genes determine cosmetic features, such as height, eye color and hair color, there are also genes that determine important biological features such as intelligence and athletic performance. Errors in the genetic sequences result in genetic disorders, one of the more common ones being Down syndrome. Since DNA is copied during reproduction, genetic disorders can often times be inherited. There are two categories in which genetic engineering can be divided into: genetic therapy and genetic enhancement. Gene therapy is the modification of genes in order to treat diseases and genetic disorder, such as Leukemia or Parkinson. It is the ethically more accepted category of genetic engineering. The more controversial category, gene enhancement, serves the purpose of, as the name says, enhancing a humans ability in a specific area, whether intelligence, athletic performance or strength. 5
Each of those two categories can then be divided into two subcategories: somatic and germline. In somatic genetic modification, whether therapy or enhancement, genes are transferred into non-sex cells. This means that only the organism affected will receive the gene modification. On the other hand, in germline genetic modification, genes are transferred into sex- cells, meaning that future generations of that organism will also be affected by the therapy or enhancement.
Important and Controversial Figures in Genetic Engineering Genentech Genentech is the very first biotechnology company and was founded in 1976 by investor Robert A. Swanson and Herbert Boyer, the scientist who laid the foundation for modern genetic engineering. The companys research focuses on five disease categories: Oncology, Immunology, Tissue Growth and Repair, Neurosciences and Infectious diseases. Developed in 1982, Genentechs first licensed product was a genetically engineered synthetic human insulin called Humulin. Today, Genentech is the second largest biotechnology company in the world based on revenue. Ian Wilmut and Keith Campbell Ian Wilmut and Keith Campbell ( 5 October, 2012) were British scientists working in the field of embryology and animal development. They are best known as the fathers of Dolly the Sheep, the first mammal to ever be cloned. Dolly was used to show that cloned animals can live and reproduce the same way as normal ones would do. Amgen 6
Founded in 1980, Amgen is the largest independent biotechnology company in the world. Like Genentech, Amgens main focus is the healthcare field.
Myriad Genetics, Inc. Myriad Genetics is a biotechnology company working in the health care field. The company was founded in Salt Lake City in 1992 and focuses on the risk assessment of several types of cancer, including breast and ovary cancer. The company drew a lot of controversy when patenting the two human genes BRCA1 and BRCA2 which can help predict breast cancer risk. Myriad started charging more than $3000 for a breast cancer test, a price that many considered as too high. After a lawsuit against the company, which led to the patents being invalidated and revalidated several times, the patents on the two genes were ultimately invalidated in June 2013 leading to a landmark ruling against the patenting of naturally occurring DNA sequences. The Big Six The Big Six biotechnology companies in agriculture are Monsanto, Bayer CropSciences, BASF, DuPont, Syngenta AG and Dow AggroSciences, Monsanto being the market leader. Together these six companies account for around 75% of worldwide seed sales. Together these six companies have amassed many controversies, however, none of them has made as many headlines as Monsanto. Monsanto Company Monsanto was founded in 1901 in St. Louis, Missouri and was one of the largest chemical companies in the world before becoming the market leader in agricultural biotechnology [11]. It is one of the most controversial companies in modern days and has made 7
headlines several times. The company became famous for having produced the herbicide Agent Orange which was used as a chemical weapon during the Vietnam War. Some other products in the companys assortment are the synthetic sweetener Aspartame, the growth hormone rBST (recombinant Bovine Somatotropin) which increases the level of milk production I cows and the highly toxic substance PCB (Polychlorinated Biphenyl) which was vastly used in the industry [11]. More than 90 percent of todays genetically modified organisms, Soy, Canola, Corn and Cotton among others, are Monsanto patents. Many people criticize Monsantos purchasing policy and believe that the company already is a monopoly in agricultural biotechnology. Some of the other controversies include the falsification of test results and amalgamation with politics.
The Ethical and Moral Issues The capabilities of genetic engineering make life itself to a subject of technical transformation. They touch on questions of a humans self and world understanding and lead to a whole new series of moral and ethical issues. Qualitatively new in genetic engineering is the ability to cause both a time reversal and a time acceleration in evolution, something not achievable with traditional methods such as selective breeding. Given the depth of intrusion caused by genetic engineering, fundamental questions about the authorization for and the limits of genetic manipulation of life arise. Moral issues are relevant in all areas of genetic engineering, however, the several areas of research and application are connected with different problems and thus need to be differentiated accordingly. Therefore, in connection with genetic engineering applications on humans, questions about medical safety, potential threats to autonomy and social consequences are at the center of discussion. 8
In agricultural applications concerns do not only include the right to intervene in nature but also the risk of releasing transgenic organisms. In the area of plant breeding the issues of biodiversity and the formation of resistance are discussed. In the area of animal breeding consequences of genetic engineering are at the center of attention; the balance between the suffering of animals and the benefits of the human are an important topic. Since a humans ethics and morals are influenced by time, culture, religion and society, it is a variable factor and changes as new developments and technologies come along. Therefore, we can see a variety of objections to controversial topics such as genetic engineering. In this paper we will divide these objections into two main categories, religious issues and secular issues. Religious Point of View To analyze the religious point of view on genetic engineering we have to first answer the question of whether the human is allowed to intervene in nature. This question is to be discussed on a creation-theological basis. The argument that genetic engineering allows the human to take on the role of god and interfere in the order of creation or that genetic engineering is against nature is too general and not justified. The generalization and vagueness of terminology is one of the biggest weak points of the ethical discussion and often times leads to proponents and opponents of genetic engineering to talk at cross purposes. According to the cultural mandate, which according to the bible was given to humanity by God and says that the human should subdue nature and have dominion over every living thing, there cannot be any creation- theological objections to genetic engineering [12][13]. The human has a cultural order which does not exclude interventions in nature. 9
Another thing to note when talking about religious objections is that it is often assumed that religion in general is opposed to genetic technology. According to Professor John Bryant at the University of Exeter this is not true [7]. Bryant argues that religious attitudes are mainly concerned with what is done with the technology rather than whether it should be done; God- given talents should be used for the well-being of others [7]. While many religious arguments do not oppose the use of somatic therapy to cure genetic disorders, there are also those that oppose any kind of invasion in human development. It is argued that altering the genome of an organism is considered as taking on the role of the creator and therefore violating the will of God. This argument can be invalidated with the cultural mandate. As we can see, the problem with all moral arguments based on Gods commands is that everyones interpretation of God and his commands is different. Those that believe genetic engineering violates Gods will must also see selective breeding as will defying as it is qualitatively the same concept. Selective breeding should not be acceptable merely on the fact that it takes a lot longer than genetic engineering. The argument of Gods will is a very biased and factually unfounded argument. The other method of genetic engineering, genetic enhancement, whether somatic or germline, is fundamentally opposed by religious groups. The general argument made is that genetic enhancement does not provide to the well-being of human beings and therefore is an unnecessary intrusion in the development of organisms; it is a luxury rather than a necessity.
Secular Point of View Since genetic engineering is still in its early phases, there are many secular arguments that say that genetic modification is morally unacceptable. 10
A central question is whether the massive use of genetic engineering negatively affects biodiversity and eliminates locally grown cultivar. Closely related is the loss of locally grown knowledge of sustainable relationships, since genetically modified crops and plants automatically adapt to their ecological environment without much care on the part of the human. Pest-resistant crops can have a direct impact on nature and the environment, if they have any kind of pests they are resistant to, other groups of organisms could be affected and destroyed by those pests. Under certain circumstances, such harmful effects are only visible in the long term, for example through gradual accumulation in the soil or by slow decline of population sizes [23]. A cultivation of herbicide-resistant crops can kill all other plants because it allows the use of nonselective herbicides. Proponents of this argument believe that if GMO seeds are continued to be planted across the world, naturally occurring seeds will eventually be extinct. Another one of the main arguments are the health issues of genetic engineering. Genetic manipulation that is done in order to solve a problem, such as a disorder, can cause several other problems. It is of highest interest to guarantee that genetically modified foods are harmless. However, this cannot even be proven by long term studies because in addition to long term effects, there is the influence of individual eating habits and preparation forms. In defense of the technology, the health risks of genetically engineering are widely regarded as hypothetical and so far, there have not been any scientifically accepted empirical studies which establish a differentiated biological and medical risk statement. And while there have been many experiments on plants and animals that provided short term success, they still cannot be applied to human beings because of the complexity of the human genome. An especially sensitive topic is the manipulation of germline DNA. Using germline therapy to prevent a genetic disorder such as diabetes being inherited by off-spring can possibly 11
cause other genetic disorders to develop in the baby and carry on into future generations [8]. This brings up the question of the moral status of embryos or not yet born humans. Often times the debate about who can be called a person is sparked. The different concepts typically implement a number of specific properties to distinguish between human and non-human individuals. Utilitarian definitions, for example, require certain abilities, such as thinking, perception of pain or self-respect. Others, especially religiously inclined people, argue that life starts when the sperm merges with the egg cell. With this argument comes the aspect of dignity. Many see genetic engineering as a threat to human dignity. This argument is often times defended with the reasoning that individuality is closely related to dignity. Genetic enhancement can result in a world where everybody wants to achieve the perfect genome which will most likely have similar, if not the same traits among different cultures. If everybodys genetic material is altered to match that perfect genome, the concept of individuality will be lost and with access to their hereditary material, people could be exploited and manipulated. Finally, from a virtue ethics standpoint, the application of genetic therapy and enhancement suggests that the accessibility of genetic manipulation will be limited to those parents who can afford it, thus creating discrimination between sectors of society [8]. If a technology is available to eliminate disease and achieve a better quality of life, should it not be available to all individuals? Genetic engineering in humans implies that we can create an elite race of human beings which are superior to the common man. Because of this, many opponents of genetic engineering say that the technology is the modern day version of Eugenics, a concept developed by the English psychologist Francis Galton in the 19 th century. The belief of Eugenics says that the genetic quality of the human population can be improved by promoting the 12
reproduction of people with desired traits, positive eugenics, and therefore eliminating people with less desired traits, negative eugenics [14]. While very popular in the early 20 th century, after World War II, many countries gave up on the concept of eugenics. However, if genetic engineering can be used to improve the genes in every human being, how is it any different than eugenics? This is even up to the current days a very controversial topic. The Proponents There are many supporters of genetic engineering, especially companies that benefit financially from the technology. The ten largest companies that support GMOs are Nestle, PepsiCo, Coca Cola, Unilever, Procter & Gamble, Mars Inc., Kellogs, Mondelez International, Johnson & Johnson and General Mills [21]. These companies along with the Big Six are currently fighting the push for GMO-labeling laws arguing that labels may mislead consumers into thinking that GMO foods are a health hazard, something that has not been scientifically proven, they claim. Many Scientists knowledgeable in the field of genetic engineering support the technology as it is not proven to harm human health. In an email interview, Dr. Dennis Dean of Virginia Techs biotechnology department said that There are many values associated with the production of useful agricultural products more cheaply, the development of new drugs, the ability to produce organisms for bioremediation etc. A biologist by the name if Ingo Potrykus has just that, the production of a useful agricultural product that is cheap and even has the potential to save thousands of lives [22]. Potrykus invented the so called Golden Rice, a genetically modified rice grain that contains beta-carotene to fight the vitamin A deficiency that children in most African countries as well as South and Southeast Asian countries have [22]. 13
Although the golden rice seems very promising, it has encountered many barriers set by opponents of GMOs. Another important and controversial actor is Mark Lynas, a British journalist and environmental activist. He made headlines for being a GMO convert. Having helped start the anti-GMO movement of the early 1990s, it was surprising when he announced that he will be supporting genetic engineering in January 2013 [20]. In his speech, he apologized for demonizing GMO foods and said that he was not educated enough on the technology to make such claims. The reason for controversy around his speech was a set of leaked documents from EuropaBio, Europes largest biotechnology company. In these documents, EuropaBio had expressed interest to have Mark Lynas act as an ambassador of genetic modification in Europe. Many believe that Lynas was paid off to convert to a pro-GMO stance and help EuropaBio, a company that has many ties to the Big Six, overcome the objections of Europeans regarding GMO crops and foods [20].
The Opponents One of the most prominent individuals in the fight against genetic engineering is Vandana Shiva. Born in India on 5 November 1952, she is known as an avid environmentalist and anti-globalist [15]. After receiving her masters degrees in Particle Physics and Philosophy of Science, she finished her PhD in Philosophy at the University of Western Ontario. In the 1970s Shiva was highly engaged in the Chipko-Movement in India. During this movement, villagers, mainly women, hugged trees in order to stop them from being felled. In 1982 Shiva founded the organization Navdanya (meaning Nine Crops) which fights against genetic engineering companies and promotes the protection of biological and cultural diversity. The 14
organization has collected several kinds of local seeds in India and planted them in seedbanks in order to preserve their existence. Shivas opinion on genetic engineering is very clear: there should not be any intrusion in nature by humankind. She calls genetically engineered crops seeds of slavery and suicide and argues that the soaring seed prices in India have resulted in many farmers being mired in debt and turning to suicide. 75 percent of Indian farmers debt comes from seed purchase and, according to Shiva, Monsantos seed monopoly is to be blamed [16]. Having reign over more than 90 percent of todays GMO patents, Monsanto can and does increase the royalty costs of seeds at will Another GMO product criticized by Shiva is golden rice, the genetically modified rice grain that contains beta-carotene. Shiva, being a proponent of biodiversity, believes that golden rice is more harmful than beneficial and says that the vitamin A deficiency could be fought with the introduction of other vegetables into the diet of children. Vandana Shiva is not alone in the fight against GMO foods and companies. The environmental organization Green Peace has a similar opinion about golden rice claiming that its introduction would lead to a contamination of other naturally occurring rice grains. The organization went on to say that even if implemented, children would have to eat several kilograms of golden rice in order to meet the daily vitamin A requirements. Scientists said that this claim was unfounded and that 400 to 500 grams a day would suffice. Greenpeace was also a large promoter of the March Against Monsanto, a protest against the largest of the Big Six. Other opponents of genetic engineering include celebrities such as Oprah Winfrey, Bill Maher, the activist Jeffrey M. Smith and Mehmet Oz.
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The Opinion and Values of Different Cultures The opinions on genetic engineering differ vastly depending on the cultural background of the people questioned. According to Dr. Dean, the publics opinion on genetic engineering is highly mixed. A small proportion of the population adamantly opposed to genetic engineering but most people dont care, or are not sufficiently aware of the debate to have an informed opinion. In a US study in 1996, the first year that genetically modified foods were commercially grown, it was determined that most Americans had a positive view on the use of biotechnology, with 78% of the respondents believing that genetic engineering would provide benefits to them. It was not until the cloning of animals that awareness increased and the approval rate dropped to 63% [9]. In Oceania the attitude towards biotechnology was quite different than in the US. In New Zealand for example, the percentage of people having a positive attitude towards genetic engineering was much lower, with only 32% of the questioned people believing that life could be improved using genetic engineering [9]. With 54% having faith in genetic engineering, the opinion of the Europeans was in between that of the New Zealanders and Americans [9]. An important detail to point out is that, generally, the support for genetic modification was highest in countries that tended to have low levels of knowledge of the technology [9]. To understand why people from different regions have different attitudes towards genetic engineering, we must identify the values and beliefs in those cultures. When talking about values we have to differentiate between values shared by people from the same culture and values of individuals. 16
According to Geert Hofstede, a Dutch social psychologist, there are four dimensions that affect the values of a culture: power distance, uncertainty avoidance, individualism- collectivism and masculine-feminine [9]. Individual values are affected by factors such as environmental attitude, religion, age, income level and education [9]. Generally, environmentally conscious people, religious people, older people, people with lower income and people with a higher level of education were found to be more cautious when asked about genetic engineering.
Current News and Controversies Genetically modified foods have been making news more and more as people have picked up on the current controversy surrounding the topic. Recently Vermont signed a bill making it mandatory that GMOs are clearly labeled for consumers to see while they are purchasing at retailers. More than 60 countries have already restricted or labeled these foods, and now one stateVermontwill also ensure that we know whats in the food we buy and serve our families, Gov. Shumlin explained to CNN [17]. Though this new law could make average grocery costs increase for the average family and will not take effect until 2016, it is the first step towards a more health-conscious America. While European Union ruled in favor of mandatory labeling of GMO products back in 1997, a brief 3 years after America introduced the product to its consumers, interestingly enough, European scientist and policymakers have made several attempts in promoting the use of 17
genetically modified food in Africa in 2014. Needless to say that most of the European Union opposed GM in their own food, the proposal is to work with African scientists to allow them to grow crops more easily and provide better nutrition for their country. The talks take place as industry data shows the increase in the planting of GM crops has practically halted in the US and as G8 countries, led by the US and Britain, press African states to liberalize their farming as part of the New Alliance for Food Security and Nutrition initiative, reports John Vidal of the Guardian [18]. Sadly many African farmers view the attempt as a new form of colonialism in their countries. China too has been pushing for a market that is less crowded with GMO foods. Since November 2013, China has rejected a total of 908,000 tons genetically modified US corn [19]. Finally, another current controversy is the ongoing search for a gay-gene. This terminology has been swirling around in the media for some time now. Biologists have been researching the same-sex activities of rams, monkeys and even fruit flies, trying to come up with possible science-based theories to explain human sexual behavior. Thankfully homosexuality was removed from the American Psychiatric Association Diagnostic and Statistical Manual in 1973, which no longer categorized it as a disease.
Conclusion Genetic engineering reaches much farther back than most people know. This new technology is the offspring of early selective breeding which first started around 10,000 BC. Throughout the millennia we have domesticated many species; today, almost every dog race in existence is a product of selective breeding. What really gave birth to genetic engineering, as we know it today, was the computer revolution as it allowed for fast knowledge gains in the field of 18
genetics. Because it is still a very young technology, genetic modification remains very controversial. There are several ethical issues, both religious and secular, brought up in the debate even though not all of them are warranted. While many religious people accept genetic therapy to cure genetic disorders, almost all oppose genetic enhancement. Those that completely reject the technology base their opinions on the argument that genetic engineering defies the will of God. Still, many seem to be accepting selective breeding although it is qualitatively the same as genetic modification, the major difference being the time scale genetic engineering and selective breeding work on. Pointing out many of the dangers genetic engineering can bring with it, secular arguments are wider ranging and more factually based. The argument that genetic engineering destroys individuality and causes discrimination between sectors of society are, at this point, farfetched. Nevertheless, we need to consider the possibility of destroying biodiversity. GMO seeds are used in more and more places around the world and could contaminate locally growing crops. Also, since there are no empirically proven studies, side effects during genetic therapy are still an important aspect that needs to be further researched. While there are many proponents and opponents with valid arguments, the opinion of the public has been found to be a mixed bag. Depending on the cultural background, the responses to genetic engineering varied from almost no acceptance, for example in New Zealand, to the majority of the population supporting it, such as in the US. Since its emergence, genetic engineering has been subject of public debate and controversies. The ability to control genetic information of organisms, and consequently the diversity of nature, evokes conflicting emotions like no other topic. The ethical debate is far from 19
being over, however, if approached the right way genetic engineering has the potential to be a very promising technology.
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[2] Genetic Engineering. Wikipedia. Wikimedia Foundation. Web. April 2, 2014.
[3] Dennis Dean, Genetic Engineering Interview Email Interview, March 24, 2014.
[4] DNA. Wikipedia. Wikimedia Foundation. Web. April 2, 2014.
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[7] John Bryant, " Faraday Paper No. 7: Ethical Issues in Genetic Modification," Faraday Papers, Cambridge: Faraday Institute for Science and Religion, April, 2007.
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[8] John C. Fletcher, "Moral Problems and Ethical Issues in Human Gene Therapy," Virginia Law Review, vol. 69, no. 3, April, 1983.
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[12] Markus Vogt, GenEthik: Grne Gentechnik in ethischer Sicht, Bayreuth: Universitaet Bayreuth, March 30, 2014.
[13] Cultural Mandate. Wikipedia. Wikimedia Foundation. Web. May 12, 2014
[14] Eugenics. Wikipedia. Wikimedia Foundation. Web. May 12, 2014
[15] Vandana Shiva. Wikipedia. Wikimedia Foundation. Web. May 12, 2014
[16] Vandana Shiva, Seeds of suicide and slavery versus seeds of life and freedom, Al Jazeera, March 30, 2014. http://www.aljazeera.com/indepth/opinion/2013/03/201332813553729250.html
[17] Dana Ford, Lorenzo Ferrigno, Vermont governor signs GMO food labeling into law, CNN, May 8, 2014. http://www.cnn.com/2014/05/08/health/vermont-gmo-labeling/
[18] John Vidal, GM crops: European scientists descend on Africa to promote biotech, The Guardian, February 24, 2014. http://www.theguardian.com/global-development/2014/feb/24/gm-crops-european- scientists-africa-promote-biotech
[19] Joseph Radford, China rejects more U.S. corn due to GMO as state sales approach, Reuters, March 25, 2014. http://www.reuters.com/article/2014/03/25/china-corn-usa-idUSL4N0MM0KY20140325
[20] Zack Kaldveer, Katherine Paul, Uncovering the Real Story Behind the 'Conversion' of Mark Lynas from Climate Change Journalist to Cheerleader for Genetically Modified Foods, AlterNet, May 12, 2014. http://www.alternet.org/food/uncovering-real-story-behind-conversion-mark-lynas- climate-change-journalist-cheerleader
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[21] Unveiled: GMO Labeling Opponents Come Out of the Shadows. Cornucopia Institute, October 22, 2013. http://www.cornucopia.org/2013/10/unveiled-gmo-labeling-opponents-come-shadows/
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