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Buletin farmasi
hospital tumpat
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PANDUAN PENGGUNAAN UBAT TITIS MATA (ENGLISH VERSION) M/SURAT : 2
PANDUAN PENGGUNAAN SALAP MATA (ENGLISH VERSION) M/SURAT : 3
PANDUAN PENGGUNAAN UBAT TITIS TELINGA (ENGLISH VERSION) M/SURAT : 4
PANDUAN PENGGUNAAN UBAT TITIS HIDUNG (ENGLISH VERSION) M/SURAT : 5
NEW MEDICATION : SQUALAMINE EYE DROPS M/SURAT : 6-7
5S HOSPITAL TUMPAT M/SURAT : 8-9
WARGA FARMASI HOSPITAL TUMPAT & LAIN-LAIN AKTIVITI
M/SURAT : 10-17

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1. Wash your hands.





2. Dry them with a clean towel or tissue.
3. Read the medication label.
4. Shake the bottle as this is indicated on the bottle or it is directed by the doctor.
5. Unscrew the cap of the bottle (for bottles with an integrated dropper, draw some liquid into the
dropper).
6. Lie down or tilt your head back and gently pull your lower eyelid down.




7. Hold the dropper (tip down) with the other hand, as close to the eye as possible without
touching it



8. While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the l
lower eyelid. Remove your index finger from the lower eyelid



9. Close your eyes slowly and gently press a finger against the inside corner of each eye and keep them
closed for approximately 1 minute to allow the medication to absorb. Straighten your head and wipe
away any extra liquid.

10. If you have more than one drop of medicine to put in your eyes, wait about 5 minutes after the first
medicine.
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1. Wash your hands.





2. Dry them with a clean towel or tissue.
3. Read the medication label.
4. Lie down or tilt your head back and gently pull your lower eyelid down.





5. Carefully, place a line (1cm) of ointment inside the lower lid while being careful not to touch your eye
with the tip of the tube.





6. Your vision can become blurry for a few moments, but it will clear quickly.
7. Close you eyes slowly and gently press a finger against the inside corner of each eye and keep them
closed for approximately 1 minute to allow the medication to absorb.




8. Straighten your head and wipe away any extra ointment.

If you are prescribed
both eye drop and eye
ointment together use
the eye drop first.
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1. Wash your hands.





2. Dry them with a clean towel or tissue.
3. Read the medication label.
4. Unscrew the cap of the bottle (for bottles with an integrated dropper, draw some liquid into the
dropper).
5. Lie on your side or tilt your head over so that the ear which needs the drops is facing upwards.
6. Pull your earlobe upwards (or if giving to a child younger than 3 years of age, pull backward and
downward) to open the ear canal and squeeze/drop the correct number of drops into the ear.





7. Keep your head tilted for about five minutes so that the drops can spread into the ear.





8. Straighten your head and wipe away any extra liquid.
9. Replace the cap on the bottle.

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1. Gently blow your nose so that your nostrils are clean.





2. Wash your hands.





3. Dry them with a clean towel or tissue.
4. Read the medication label.
5. Unscrew the cap of the bottle (for bottles with an integrated dropper, draw some liquid into the
dropper).
6. Tilt your head back.





7. Hold the bottle or dropper above your nostrils and gently squeeze the correct number of drops into the
nostrils.




REFERENCES:
1. American Society of Health-System Pharmacists.
Available from: http://www.safemedication.com/safemed/MedicationTipsTools/HowtoAdminister
2. Know your medicine: Self-care & Self-medication; Pamphlet.
Available from: http://www.knowyourmedicine.gov.my
By: Owi Siew Ai
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Squalamine Eye Drops
What is Squalamine?
Squalamine is an anti-angiogenic amino sterol derived from cartilage
of the dogfish shark, Squalus acanthus..
Mechanism of Action
It blocks ion transporters that regulate cell function by controlling
pH and metabolism.
When bound to calmodulin, squalamine also blocks the action of
vascular endothelial growth factor (VEGF) and integrin
expression,thereby inhibiting angiogenesis (stop formation of new
blood vessel) in the retina and macula.
A History of Squalamine
Research
Initially, Genaera Corporation
developed squalamine as an intravenous formulation for wet-age
related macular degeneration (AMD) a degenerative retinal eye disease that
causes a progressive, irreversible, severe loss of central vision.
After Phase 1 and Phase 2 clinical trials, this project was discontinued due to
financial and subject-recruitment issues in 2007.
Squalamine has been shown to inhibit new vessel formation without significant regression of existing
lesions, and, depending on the lesion composition, combination with adjunctive
therapies may be appropriate.
Then this project was acquired by Ohr Pharmaceutical, which continued the
development of squalamine in a topical eye drop formulation.
This study has entered phase II clinical trial to evaluate the safety and efficacy of topical ophthalmic
squalamine lactate eye drops and expected to complete in December 2014.
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Current Treatment
VEGF inhibition therapy is the best available treatment for wet AMD but is limited by the need for
repeated intravitreal injections.
Options currently include either a full-length recombinant monoclonal antibody (bevacizumab/
Avastin) or a highly afnitized fragment of the antibody (ranibizumab/Lucentis), or a pegylated
aptamer (pegabtanib sodium/Macugen).





Conclusion
Thus, with the development of squalamine eye drop which designed for self administration, may
provide several potential advantages over the FDA approved current standards of care, which
require intravitreal injections directly into the eye.

References
Chakravarthy, U., Soubrane, G., Bandello, F., Chong, V., Creuzot-Garcher, C., & Dimitrakos, S. A. (2006).
Evolving European guidance on the medical management of neovascular age related macular
degeneration. Br J Ophthalmol , 11881196.
Emerson, M. V., & Lauer, A. K. (2008). Current and emerging therapies for the treatment. Clinical
Ophthalmology , 377-388.
http://clinicaltrials.gov/ct2/show/NCT01678963
http://www.visionaware.org/blog/visionaware-blog/a-new-clinical-trial-squalamine-eye-drops-for-wet-
amd-and-retinal-vein-occlusion/12


VS
By : Hasanah Muhammad
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SELAMAT DATANG & SELAMAT BERKHIDMAT DI HOSP. TUMPAT
Menamatkan latihan Provisional Registered Pharmacist
(PRP) di HRPZ II pada 2012
Memegang Ijazah Sarjana Muda Farmasi USM.
Mula melapor diri di Hospital Tumpat pada Januari 2013
Melapor diri di Hospital Tumpat pada Oktober 2013.
Menamatkan latihan Provisional Registered Pharmacist
(PRP) di HRPZ II sebelum bertugas di Hospital Tumpat.
Merupakan pemegang Ijazah Sarjana Muda Farmasi UIAM
Mula berkhidmat di Hospital Tumpat pada 2 Mac 2014
Sebelum ini telah berkhidmat di KK Putrajaya Presint 9 selama 2 tahun (2012-
2014)
Lulusan Diploma Penolong Pegawai Farmasi dari KPJ International University
Mula berkhidmat di Hospital Tumpat pada Mei 2013
Telah berkhidmat di Klinik Kesihatan Mahligai, Klinik
Kesihatan Wakaf Che Yeh, dan Hospital Tengku Anis
Lulusan Diploma Pembantu Farmasi Makmal & Stor
Petaling Jaya
PN NORDALILA SHAFII, PEN. PEG. FARMASI U29
PN LOW GIM LAY, PEN. PEG. FARMASI U32
CIK OWI SIEW AI, PEGAWAI FARMASI U41
PN HASANAH MUHAMMAD, PEGAWAI FARMASI U41
2005-2011 mula berkhidmat di Hospital Permai Johor Bharu
2011 2013 bertukar ke KK Kuala Balah Jeli, Kelantan.
Mula berkhidmat di Hospital Tumpat pada Mei 2013.
Lulusan Diploma Pembantu Farmasi Kolej Perubatan DiRaja Perak
EN MOHD RIZALMIE MUHD NOR, PEN. PEG. FARMASI u29
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SELAMAT BERKHIDMAT DI TEMPAT BARU





2012-2013 Klinik Kesihatan Mahmoodiah Johor Bharu
2013 sekarang Berkhidmat di Hospital Tumpat.
Lulusan Diploma Penolong Pegawai Farmasi Kolej Sains
Kesihatan Bersekutu Sungai Buloh.
1999-2001 Berkhidmat di Klinik Kesihatan Bera 32
2001-2012 Berkhidmat di Klinik Kesihatan Triang
2012-2013 Berkhidmat di Hospital Kuala Krai
2013 sekarang Berkhidmat di Hospital Tumpat
Lulusan Diploma Pembantu Farmasi Makmal & Stor
Petaling Jaya
2010-2013 berkhidmat di Hospital Dungun
2013 sekarang berkhidmat di Hospital Tumpat
Lulusan Diploma Penolong Pegawai Farmasi
Kolej Universiti MAHSA 2007-2010.
PN MARIYAH HJ MAT, PEN. PEG. FARMASI U29
PN SITI NORNABILAH AB RAHMAN, PEN. PEG. FARMASI U29
PN WAN NURUL ATIKAH WAN MAMAT, PEN. PEG. FARMASI U29
Bertukar ke
HRPZ II, pada
Februari 2013
Bertugas di KK
Penambang, Kota Bharu
bermula Mei 2013
Bertukar ke BPFK, Petaling
Jaya pada November 2013
Bertugas di KK Kg Lalang,
Baling, Kedah bermula Mac 2014
PN NAZMI LIANA AZMI
PEG. FARMASI U44
PN YU YONG KING
PEG. FARMASI U44
EN MOHD AZNAN RAJID
PEN. PEG. FARMASI U29
PN RAJA RAHBANIAH
RAJA JAAFAR, PEN. PEG.
FARMASI U29
Suntingan & susunan : Ummi Wahida, Rizalmie & Siti Hamisah
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MAJLIS PERPISAHAN
PF U44 PN YU YONG KING, PPF U29 PN RAJA RAHBANIAH &
PPF U29 MOHD AZNAN RAJID
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EN. EH CHOI
A/L CHAU ONN
Duta Kenali Ubat Anda,
Tumpat
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PENYELARAS AKREDITASI:
PF Siti PAUZIAH
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PENYELARAS ADUAN
PELANGGAN :
pf Siti FATIMAH
KETUA PENGAWAL
DOKUMEN iso : pf UMMI WAHIDA
Wakil Pengurusan ISO:
PF Siti Hamisah
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Penyelaras : Pn. Siti Pauziah
Ketua Editor: Pn. Siti Hamisah

Editor
Pn. Ummi Wahida
Pn. Siti Fatimah
Cik Owi Siew Ai
Pn. Hasanah
En. Mohd Rizalmie
Pn. Mariyah