SEEK Pulmonary Vascular Disease, Diffuse Lung Disease, Asthma, Pleural, Occupational Lisa Moores, MD, FCCP CHESTQUESTION 1 A 56-year-old man with known cirrhosis and portal hypertension complains of progressive dyspnea on exertion over the past 6 months. His symptoms have progressed to the point that he is short of breath with minimal exertion and occasionally at rest. He has no other medical problems. VOLUME 21, QUESTIQUESTION 1 His BP is 100/60 mm Hg, pulse rate is 88/min, and respiratory rate is 14/min. Physical examination reveals bilateral jugular venous distention to 5 cm above the angle of the jaw. A grade III pansystolic murmur along the left sternal border with inspiratory accentuation is heard. Significant ascites and lower extremity edema also is present. VOLUME 21, QUEST!