"PowderedPlacentaHominiswasusedfor57casesofinsufficient

lactation.Within4days,48womenhadmarkedlyincreasedmilk
production,withtheremainderfollowingsuitoverthenextthree
days."Bensky/Gamble.1997.MateriaMedica,EastlandPress,549.
"Ithasbeenshownthatthefeedingofdesiccatedplacentatowomen
duringthefirstelevendaysafterparturitioncausesanincreasein
theproteinandlactosepercentofthemilk...Allthemotherswere
receivingthesamediet,andtothesecondset0.6mgofdesiccated
placentawasfedthreetimesadaythroughouttheperiod.Certain
definitedifferencesintheprogressofgrowthofthetwosetsof
infantsaretobeobserved.Itisevidentthattherecoveryfromthe
postnataldeclineinweightishastenedbytheconsumptionofmilk
producedundertheinfluenceofmaternallyingestedplacenta."
McNeile,LyleG.1918.TheAmericanjournalofobstetricsand
diseasesofwomenandchildren,77.W.A.Townsend&Adams,original
press:UniversityofMichigan.
PlacentaasLactagagon
SoykovaPachnerovaE,et.al.(1954).Gynaecologia138(6):617627.
Anattemptwasmadetoincreasemilksecretioninmothersby
administrationofdriedplacentaperos.Of210controlledcases
only29(13.8%)gavenegativeresults181women(86.2%)reacted
positivelytothetreatment,117(55.7%)withgoodand64(30.5%)
withverygoodresults.Itcouldbeshownbysimilarexperiments
withabeefpreparationthattheeffectivesubstanceinplacentais
notprotein.Nordoesthelyofilisedplacentaactasabiogenic
stimulatorsothatthegoodresultsofplacentaadministration
cannotbeexplainedasaformoftissuetherapyperos.Thequestion
ofahormonalinfluenceremainsopen.Sofaritcouldbeshownthat
progesteroneisprobablynotactiveinincreasinglactationafter
administrationofdriedplacenta.
Thismethodoftreatinghypogalactiaseemsworthnotingsincethe
placentapreparationiseasilyobtained,hasnotsofarbeen
utilizedandinourexperienceissuccessfulinthemajorityof
women.
Effectsofplacentophagyonserumprolactinandprogesterone
concentrationsinratsafterparturitionorsuperovulation.
BlankMS,FriesenHG.:JReprodFertil.1980Nov60(2):2738.
Inratsthatwereallowedtoeattheplacentaeafterparturition
concentrationsofserumprolactinwereelevatedonDay1but
concentrationsofserumprogesteroneweredepressedonDays6and8
postpartumwhencomparedtothoseofratspreventedfromeatingthe
placentae.InratstreatedwithPMSGtoinducesuperovulationserum

prolactinandprogesteronevaluesweresignificantly(P<0.05)
elevatedonDays3and5respectively,afterbeingfed2grat
placenta/dayfor2days.However,feedingeachrat4gplacenta/day
significantly(P<0.02)loweredserumprogesteroneonDay5.
Oestrogeninjectionsorbovineorhumanplacentainthediethadno
effect.Theorganicphaseofapetroleumetherextractofrat
placenta(2gequivalents/day)loweredperipheralconcentrationsof
progesteroneonDay5,butotherextractswereineffective.We
concludethattheratplacentacontainsorallyactivesubstance(s)
whichmodifybloodlevelsofpituitaryandovarianhormones.
PostpartumDepression
http://placentamom.weebly.com/uploads/2/4/8/3/2483180/
crh_study.pdf
MaternalIronDeficiencyAnemiaAffectsPostpartumEmotionsand
Cognition
JohnL.Beard,et.al.J.Nutr.135:267272,2005.
ABSTRACTTheaimofthisstudywastodeterminewhetheriron
deficiencyanemia(IDA)inmothersalterstheirmaternalcognitive
andbehavioralperformance,themotherinfantinteraction,andthe
infantsdevelopment.Thisarticlefocusesontherelationbetween
IDAandcognitionaswellasbehavioralaffectintheyoungmothers.
Thisprospective,randomized,controlled,interventiontrialwas
conductedinSouthAfricaamong3groupsofmothers:nonanemic
controlsandanemicmothersreceivingeitherplacebo(10gfolate
and25mgvitaminC)ordailyiron(125mgFeS04,10gfolate,25mg
vitaminC).Mothersoffulltermnormalbirthweightbabieswere
followedfrom10wkto9mopostpartum(n81).Maternalhematologic
andironstatus,socioeconomic,cognitive,andemotionalstatus,
motherinfantinteraction,andthedevelopmentoftheinfantswere
assessedat10wkand9mopostpartum.Behavioralandcognitive
variablesatbaselinedidnotdifferbetweenirondeficientanemic
mothersandnonanemicmothers.However,irontreatmentresultedina
25%improvement(P0.05)inpreviouslyirondeficientmothers
depressionandstressscalesaswellasintheRavensProgressive
Matricestest.Anemicmothersadministeredplacebodidnotimprove
inbehavioralmeasures.Multivariateanalysisshowedastrong
associationbetweenironstatusvariables(hemoglobin,mean
corpuscularvolume,andtransferrinsaturation)andcognitive
variables(DigitSymbol)aswellasbehavioralvariables(anxiety,
stress,depression).Thisstudydemonstratesthatthereisastrong
relationbetweenironstatusanddepression,stress,andcognitive
functioninginpoorAfricanmothersduringthepostpartumperiod.
Therearelikelyramificationsofthispoorer"functioning"on
motherchildinteractionsandinfantdevelopment,butthe
constraintsaroundthisrelationwillhavetobedefinedinlarger
studies.

http://www.tayloryourbirth.com/M2%20%20impact_fatigue_PPD.pdf
http://www.tayloryourbirth.com/M2%20%20haveweforgotten.pdf
PainRelief
PlacentaforPainRelief:
Placentaingestionbyratsenhancesyandnopioidantinociception,
butsuppressesAopioidantinociception
JeanM.DiPirro*,MarkB.Kristal
Ingestionofplacentaoramnioticfluidproducesadramatic
enhancementofcentrallymediatedopioidantinociceptionintherat.
Thepresentexperimentsinvestigatedtheroleofeachopioid
receptortype(A,y,n)intheantinociceptionmodulatingeffectsof
PlacentalOpioidEnhancingFactor(POEFpresumablytheactive
substance).Antinociceptionwasmeasuredona52jChotplatein
adult,femaleratsaftertheyingestedplacentaorcontrolsubstance
(1.0g)andaftertheyreceivedanintracerebroventricularinjection
ofayspecific([DPen2,DPen5]enkephalin(DPDPE)0,30,50,62,
or70nmol),Aspecific([DAla2,NMePhe4,Gly5ol]enkephalin
(DAMGO)0,0.21,0.29,or0.39nmol),ornspecific(U62066
spiradoline0,100,150,or200nmol)opioidreceptoragonist.The
resultsshowedthatingestionofplacentapotentiatedyandn
opioidantinociception,butattenuatedAopioidantinociception.
ThisfindingofPOEFactionasbothopioidreceptorspecificand
complexprovidesanimportantbasisforunderstandingtheintrinsic
painsuppressionmechanismsthatareactivatedduringparturition
andmodifiedbyplacentophagia,andimportantinformationforthe
possibleuseofPOEFasanadjuncttoopioidsinpainmanagement.