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What is the mechanism of action of Vit. K ?

Vit. K has an essential role in the synthesis of coagulation factors by hepatic


cells
Thiazide diuretics cause all the following except :
a- Hypokalamia
b- Hypercalcemia
c- Hyperuricamia
d- Hyponatrimia
e- Hyperglycemia
f- Hypernatremia

Treatment with anti-arrhythmic drug depends on the followings except :


a- Type of medication
b- Period of medication
c- Patient sex
Elimination of Digoxin is mainly by :
a- Kidney
b- Liver
c- Both
d- None of the above
Dobutamine is given I.V. because :
a- It is not stable in the gastric PH
b- It is needed in large quantities in case of oral route
c- It is eliminated very quickly

Amiloride as triamterene causes :


a- CNS disturbance
b- Hyperkalamia
c- Hypokalamia
d- Not affect in K [ Potassium ]

What is the most drug can cause damage if it is given OTC ?


a- Captopril
b- Warfarin
c- Chlorothiazide
d- Rifampicin

Drug physical dependence is as same as drug abuse


a- True
b- false

Mention two Thiazide diuretics ?


1- Chlorothiazide 2- Hydrochlorothiazide

What is the difference between the following anti-fungal ?


Miconazole = local & systemic
Amphotercin = parenteral only
Griseofulvin = oral

Give the indication of the following drugs :


1- Gimfibrazole for hyperlipidaemia
2- Cisapride for gastro-oesophegyal reflux
3- Fluoxetin SSRI [ selective serotonin reuptake inhibitor.]( Antidepressant )
4- Carbimazole for hyperthyrodism
5- Imipramine Tricyclic anti-depressant
6- Ipratropium Br. Anti muscarinic as broncho-dilator

All
abcde-

are anti-metabolic except :


Methotrexate
Flurouracil
Cytabrin
Azothiopin
Cyclophosphamide

Cefaclor
a- Ist,
b- 2nd,
c- 3rd,
d- None

is :
Generation Cephalosporin
generation Cephalosporin
generation Cephalosporin
of the above

Which Aminoglycoside antibiotic can be taken orally ?


a- Gentamycin
b- Neomycin
c- Amikacin
d- Tobramycin

Teicoplanin antibiotic has similar effect on Gram positive as :


a- Vancomycin
b- Jamicacin
c- Gentamycin
d- Kanamycin
Which one is not Tetracycline ?
a- Minocycline
b- Demeclocycline
c- Doxycycline
d- Clindamycin

Which one is not Ca channel blocker ?


a- Verapamil
b- Deltiazem
c- Amlodipine
d- Cinnarzine
Mesalazine is used for the treatment & maintenance of remission of Ulcerative Co
litis
Imipenam [ Carbapenam ] is the first Thiemamycin Beta - Lactam anti-biotic
All
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These medications are used in treating T.B. except :


Cyclosporine
INH
Cycloserine
Rifampicin

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All These drugs are anti-cholinergic except :


Ipratropium
Atropine Sulphate
Benzatropine Methylate
Dobutamine

All
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Of These are antibiotics except :


Zalcitabine
Cefaprozil
loefloxacin
Cefopodoxime

There is one drug is used for HIV :


a- Zalcitabine
b- Kinasterdin
c- Cefaprozil
d- Enoxacin

Which one is Suprax ?


a- Cefixime
b- Itraconazole

Which one is Sporanox ?


a- Cefixime
b- Itraconazole
All of These can be used in treating leprosy except :

abcd-

Dapson
Rifampcin
Clofazimine
INH

Which is not Aminoglycoside ?


a- Netilmicin
b- Tobramycin
c- Kanamycin
d- Lymecyclin
Betahistine HCL is used
a- For Mienieres disease
b- Antihistamine
c- Analgesic
d- a & b

Which one is not 5HT3 antagonist ?


a- Tropisetron
b- Ondansetron
c- Domperidone [ Motilium ]
d- Granisetron

Which is not oral anti-coagulant ?


a- Warfarin
b- Enoxaprine
c- Phenidione
d- Nicoumolone

Which is correct ? Diazepam


a- Can cause muscle spasm
b- Is taken I.M. only
c- Is derivative from Morphine
d- Is not used for long term

The
abcd-

duration of treatment of T.B. by CTC is :


One week
Two months
One month
6 months

Metoclopramide is a dopamine antagonist acts centrally by blocking Vomiting Cent


er [ V.C. ] and
peripherally acts on the Chemo-Receptor Trigger Zone [ CTZ ] to be used as antiemetic
Which one is contra-indicated in pregnancy :

abcd-

Sucralfate
Ethambutol
Chlorphenramine
Ciprofloxacin

What is the definition of Bioavailability of the drug ?


Is the quantity of the active constituent of the drug
absorbed by the blood through the intestine or any other
route in a certain period of time .
OR : It is the conc. of the drug in the blood in a certain
period of time
Give an ex. Of a drug induce Hepatotoxicity ?
1- Paracetamol
2- Ketoconazole
3- Rifampicin
4- Quinolones
Give an ex. Of a drug induce Nephrotoxicity
Aminoglycosides as Gentamycin
Give the anti-dote for each of the following :
a- Heparin Protamine Sulphate
b- Paracetamol Acetyl cystine
c- Warfarin Vit. K
d- Morphine Naloxone
What is the generic name of Vit. B 12 ?
Cyanocobolamine
Zidovudine is used for HIV
What is the meaning of poor patient compliance ?
The patient did not take the medication properly [ not proper
dose, not proper time ] may be due to the dose regimen is not
easy or the dose is high, or the side effects is clear
Fluxotine (Prozac) is selective serotonin re-uptake inhibitor
Omeprazole is Losec is a proton pump inhibitor
Mention two diseases cause Edema ?
1- Renal Failure
2- Congestive Heart failure
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Warfarin Aspirin
Insulin B-Blockers
Heparin Aspirin & Ampicillin
Warfarin Vit. K
Warfarin Phenobarbital
Spironolactone Digoxin

7- ACEI Pot. Sparing diuretics


Generic
a-Vit.
b-Vit.
c-Vit.
d-Vit.
All
abcde-

name of :
B1 Thiamine
B2 Riboflavin
B6 Pyridoxin
B12 Cyanocobolamine

of these are the components of Calamine lotion B.P. except :


ZnO
calamine
Sod. Citrate
Bentonite
Sod. Sulphate

Terbinafine is used topically for :


a- Eczema
b- Candida
c- Fungal infections
Which one is not contra-indicated in pregnancy ?
a- Captopril
b- Enalpril
c- Lisinopril
d- Methyldopa
PCP
abcd-

[ Pneumocystis Corini Pneumonia ]


Virus
Bacteria
Parasite
Mycobacterum

Which of the following is not antibiotic ?


a- Erythromycin
b- Cefprozil
c- Ceprodoxin
d- Finasteride
Which one is used for Benign Prostatic Hyperplasia [ BPHP ]?
a- Flumazenil
b- Cefprozil
c- Mivacurim
d- Finasteride
All
abcd-

of these are third generation Cephalosporin except :


Cefixime
Cefopodoxime
Ceftriaxone
Cefotaxime

Which of the following is not mucolytic ?

abcde-

Bromohexin
Carbocistene
Ambroxol
guaphenesin
Dextromethorphan

Which one is anti-platelet ?


a- Ticlopidine
b- Desfluron
c- Aldesleukin
d- Atovaquon
All
abcd-

of these anti-neoplastic except :


Aldesleukin
Teniposide
Pentostatin
Amlodipine

Which is not Benzodiazepine ?


a- Temazepam
b- Nitrozepam
c- Loprazolam
d- Clozapine

Metoclopramide gives its antiemetic effect through :


a)Prepheral action
b)Dopameniric receptor
c)Muscarinic receptor
d)All of the above

Hydralazine is used as antihypertensive through :


a)Vasodilatation
b)Diuritics
c)Decreasing the cardiac output
d)All of the above

Dobutamine is used as :
a)Parasympathomimatic
b)In cardiac surgery
c)Hypotensive
d)All of the above

A patient has a prescription of enalapril with KCl .. what are you ask him :
a)Any product of KCl you need?
b)You take any other antihypertensive?
c)you need syrup or tab.
d)Non of the above

ACEI is used for the treatment of :


a)asthma
b)C.H.F
c)Hypertention
d) B&C

All og the following have G.I.T upset EXEPT :


a)Phenytoin
b)Phenobarbiton
c)Ethosuximide
d)Benzodiazepam

Dolmol is :
a)Paracetamol with analgesic and
b)Paracetamol with analgesic and
c)Non-paracetamol with analgesic
d)Non-paracetamol with analgesic

antinflamatory effect
without antinflamatory effect
and antinflamatory effect
and without antinflamatory effect

Clonidine is used as :
a)Antihypertensive acting centrally
b)Prevention teh recurrent of maigrane
c)A&B
d)Non of the above

The drugs transfer through the cell membrane by :


a)Aqueous diffusion
b)Osmotic pressure
c)Lipid dissolve
d)Non of the above

All the following are non-sedating antihistaminic EXCEPT :


a)Astemizole
b)Cetrizine HCl
c)Loratidine
d)Clemastine

All the following are Antibacterial EXCEPT :


a)Zalcitabine
b)Lomefloxacin
c)Cefprozil
d)Cefpodoxine

All of the following can be used in leprosy EXCEPT :

a)Dapson
b)Clofazimine
c)Rifampicin
d)INH

All of the following are ACE inhibitor EXCEPT :


a)Enalpril
b)Lisinopril
c)Quinapril
d)Zarapril

U.T.I (Urinary Tract Infection) is :


a)Gram negative
b)Gram positive
c)Mixed
d)ALL of the above

Ipeca induce vomating through :


a)Stimulation of stomach
b)Stimulation of Chemoreceptor Trigger zone
c) A & B
d) Non of the above

In type I diabetes use:


a)Insulin
b)Glibenclamide
c)A & B
d)Non of the above

Type II Diabetes use :


a)Diet regimen only
b)Oral hypoglycemic agent
c)Insulin
d)All of the above

At cardiac shock the drug of choice is :


a)Epinephrine
b)Propronol
c)Hydrocortisone
d)Saline solution

Which of the following has no vasodilitation effect :


a)Methyl dopa
b)Enalopril
c)Hydralazine
d)Prazosin

Maximum dose of Captopril is :


a)150 mg/day
b)250 mg/day
c)200 mg/day
d)300 - 450 mg/day

Amantadine used for the following EXCEPT :


a)Antiviral
b)Influenza A
c)Antiparkinsonism
d)Influenza B

Acetohexamide is:
a)Antimalaria
b)Anticoagulant
c)Antidepressant
d)Hypoglycemic drug

Wich one of these is pro-drug :


a)Ampicillin
b)Erythromycin
c)Pivampicillind
d)All of the above

The action of Captopril :


a)Inhibit Conversion of Angiotensin I to II
b)Effective hypotensive drug when other (B-blocker & diuritic) are contraindica
ted
c)Have a valuable role in heart failure
d)All of the above

Aspirin is recomended with :


a)Antifungal therapy
b)Chicken box
c)Influanza sympoms
d)Dysmenorrhea

All of the following are anions EXCEPT :


a)Phosphate
b)Acetate
c)Sodium
d)Chloride

Emesis is iduced due to :


a)Pacetamol poisoning
b)Seizurs
c)C.N.S Depression
d)Causatic substance ingestion

Nitroprusside sodium is:


a)A potent Vasodilator
b)A potent diuretic
c)A potent vasoconstrictor
d) type III antiarrythmatic agent

Praziquental used for bilharziasis :


a)Causes a loss of inter-cellular calcium of worms
b)Used for malaria
c)Has trade name Biltricide
d) A & C

Nitrofurantoin is indicated for :


a)U.T.I
b)U.R.T (Upper Rispiratory Tract)
c)Viral infecton
d)G.I.T infection

Gemfibrozil is:
a)Increas HDL & Triglyceride
b)Increase HDL & decrease Triglyceride
c)Increase HDL & LDL
d)Increase LDL & Triglyceride

Zinnate contains:
a)Clavulanate penicilline
b)Cefuroxime
c)Cefaclor
d)Streptomycin

Cytotec is used for :


a)Gastric and doudenal ulcer
b)Contraindicated in pregnancy
c)U.R.T infection
d) A & B

The instruction for a patient taking Metamucil or any other bulk forming laxativ
e (e.g. Methy cellulose) to :
a)Adequate fluid intake should be aintained to avoid intestinal obstrection
b)Administration of charcoal

c)Antagonize by Diuretics
d)Non of the above

All of these are calamine lactate B.P component EXCEPT :


a)Zinc oxide
b)Sodium Sulphate
c)Bentonute
d)Sodium Citrate

Generic name of vitamin B2 is :


a)Thiamine
b)Niacine
c)Ribofavine
d)pyridoxine

Spironolactone is interacts with :


a)aspirin
b)Insulin
c)Digoxin
d)INH

Fluoxetine (prozac) is :
a)SSRI antidepressant
b)Selective seratonin reubtake inhibitor
c) A & B
d)Non of the above

Poor patient compliance means:


a)patient not taken medication neither in the proper time nor in proper dose
b)patient tak medication not as the physician advice
c)A & B
d)The rate of absorption is higher than that of elimination

Omeprazole :
a)acts as proton pump inhibitor
b)Blocks the hydrogen-potassium ATP enzyme system
c)A &B
d)None of the above[/align]

All of the following are macrolides EXEPT :


a)Clarithromycin
b)Roxithromycin
c)Erythromycin
d)Clindamycin

All of the following are used as Antiepileptic EXEPT :


a)Sod. valproate
b)Carbamazepine
c)Nedocromil
The main use of metronidazole is:
a)Antiamoebiasis
b)Antihelmintic
c)Antibiotc
d)Antimalaria

The diuretic which is used with captopril is :


a)Aldactone
b)Ethacrynic acid
c)furesemide
d)None of the above

Atropine is used as pre-anesthitic to :


a)Give skeletal muscle relaxation as the effect of parasympathatic
b)decrease salive
c)Help the sleepin effect of anesthetic
d)Treat the side effect of anesthetic

The responsibility of pharmacist work in hospital is :


a)Admenstration of the drug
b)deal with patient
c)deal with drug interaction
d)monitor affect of the drug

Protien bound drugs forming a compound which is :


a)Inactive while the free part is active
b)Highly active while the free part is inactive
c)less active whike the free part is active
d)active while the free part is more active

All the following are controlled drugs EXEPT :


a)stesolid
b)Diazepam
c)Imipenem
d)primidon

Pseudomembrane colitis is a side effect of :


a)Vancomycin
b)Clindamycin
c)Reserpine
d)I.N.H

Malignant Hypothermia is usually a side effect of :


a)Anaeshtesia
b)Azathropin
c)Phenytoin
d)Aspirin

Vasopressine is used for treatment of :


a)Diabetes of insipidus
b)Diabetes mellitus type I
c)Diabetes mellitus type II
d)Antihypertensive

All of the following are used as cough depressant EXCEPT :


a)Guaifenesin
b)Dextromethorphane
c)Codiene Phospahte
d)Morphine hydrochloride

Which one of the following is taken orally :


a)Estrogen
b)Estrogen gluconate
c)Estrogen malate

Drug of choice to treat Leishmaniasis :


a)Sod. Stibogluconate
b)Sod. Cromoglycate
c)Metronidazole
d)Mebendazole

Sumatriptan (5-HT1 agonist) is used for :


a)Hypertension
b)Migrane and headach
c)Angina pectoris
d)Epilepsy

In patient with Renal disease one of these drugs is not used due to Hyperkalemia
:
a)Bumetanide
b)Amiloride
c)Fursemide
d)Ethocrynic acid

In patient who asking for a decongestant , which drug is the best choice :
a)Terfenadine

b)Astimazole
c)Loratedine
d)All of the above

Allopuranol affects through enzyme action by :


a)Decarboxylase inhibition
b)Xanthine oxidase inhibition
c)Cycloxygenase inhibition
d)All of the above

Which one of the following is consider as enzyme inducer :


a)Rifampicin
b)Chloramphinicol
c)cimetidine
d)Vit C

The new non-sedating antihistamine are related to :


a)H2 - antagonists
b) H1 - antagonists
c)Both H1 & H2 antagonists
d)Non of the above

When a patient comes to you with a prescription of penicilline , sulfonamides ..


you should :
a)Ask patient to avoid taking drug with food
b)Ask him to avoid taking the drug with milk
c)Ask him if he is an allergic to this drug
d)All of the above

Which one of the following is not Tetracycline :


a)Minocycline
b)Doxycycline
c)Demeclocycline
d)Clindamycin

TB should be treated with :


a)single drug to avoid resistance
b)Two drugs to shorten the therapy period
c)three to four drugs to ensure eradication of microorganism
d)Non of the above

Food poisoning is caused by :


a)Virus
b)Bacteria
c)Worms
d)Tinea

Which one of the following is the drug of choice for Hypothyrodisim :


a)Carbimazole
b)Thyroxine
c)Iodine
d)Propylthiouracil

Which one of these diuretics is more potent than the other :


a)Fursemide
b)Torasemide
c)Ethacrynic acid
d)Bumetanide

Phenylephrine is used for :


a)Decongestant
b)Sympathomematic
c)Running nose
d)All of the above

A patient comes to you with prescription pf INDERAL, and you note that he wheezi
ng .. you should?.
a)Give him the medicin
b)Be contact with him
c)Call the doctor to ask him about the prescription
d)Ask the patient if he asthmatic

Theophylline is :
a)Bronchodilator
b)B2 agonist
c)ANticholinergic
d)All of the above

Pentobarbital differ from Phenobarbital in :


a)Longer duration
b)Faster in action
c)a + b
d)not used any more

All the following are considered to be beta


a- Ceftriaxone
b- Piperacillin
c- Ofloxacillin
d- Imipenem

lactam type antibiotics,EXCEPT

The most common side effect related to the use of Aluminium containing antacids
is
a- Nausea,Vomiting
b- Constipation
c- Diarrhoea
d- GlT bleeding

Salmeterol is:a- beta-agonist


b- Methylxanthine
c- Mast-cell- stabilizer
d- Muscarinic antagonist

Which of the following is not a beta-lactam abntibiotic?


a- Aztreonam
b- Imipenem
c- Streptomycin
d- Ampicillin

Which of the following is not indicated for use in children less than 12 years o
ld?
a- Domperidone (Motilium)
b- Doxycycline (Vibramycin)
c- Chloramphenicol (Chloromycetin)
d- Astemizole (Hismanal)

Which of the following drugs not used in Acute pain?


a- Morphine
b- Phentanyl
c- Naloxone
d- Dexamethasone

Which of the following ?-blocker used in ophthalmic preparation?


a- Timolol
b- Propranolol
c- Labetalol
d- Pindolol

The dose of Klacid (Clarithromycin) is:a- three times per day


b- twice per day

c- once daily
d- four times per day

The trade name of Fosinopril is:a- Capoten


b- Reinetic
c- Zestril
d- Monopril

Advantage of Salbutamol over other bronchodilator:


a- Long acting
b- More potent
c- Low side effect
d- Fast Acting

Diltiazem is:
a- beta blocker
b- Ca channel blocker
c- Na channel blocker
d- Alph blocker

Qod means:a- three times daily


b- every day
c- four times daily
d- every other day

Qid means:a- three times per day


b- two times per day
c- four times per day
d- once daily

About Tetracycline all of the followings are right except:a- It can suppress the growth of bacteria
b- It binds to bacterial Ribosome
c- Active against G+ve and G-ve
d- Save for children use without affecting the color of the teeth

Opioid toxicity can be treated with:-

abcd-

Paracetamol
Naloxone
Deferoxamine
Vitamin K

Which of the following drugs inhibit the liver enzymes?


a- Paracetamol
b- Epanutin
c- Cimitidine
d- Aspirin

33- Which of the following drugs Induce the liver enzymes?


a- Rifampicin
b- Ranitidine
c- Cimitidine
d- Acyclovir

Side effect of Atropine:a- Diarrhea


b- Headache
c- Dry mouth
d- Constipation

Vassoprossine used in treatment of:


a- Diabetes mellitus
b- Diabetes Insipidus
c- Hyperthyroidism
d- Hypothyriodism

Side effect of Buscopan:


a- Diarrhea
b- Headache
c- Dry mouth
d- Constipation

Pseudomembranous colitis is treated with:a- omeprazole


b- mebendazole
c- metronidazole
d- Amoxil

Quality control is the control of:a- condition


b- specification
c- shelf life

Streptokinase is indicated for:a- Pulmonary embolism


b- Impaired fat absorption
c- Tuberculosis
d- Neoplastic anemia

Neostigmine should stopped before Pregnancy by:


a- two weaks
b- two months
c- two Years
d- none of the above