ORIGINAL ARTICLE

Year : 2010 | Volume : 1 | Issue : 1 | Page : 8-9

Studies on comparison of the efficacy of terbinafine 1% cream and butenafine 1% cream for the
treatment of Tinea cruris
Sudip Das1, JN Barbhuniya2, Indranil Biswas3, S Bhattacharya4, PK Kundu4
1
Department of Dermatology, NRS Medical College, Kolkata, India
2
Department of Dermatology, School of Tropical Medicine, Kolkata, India
3
Department of Pharmacology, NRS Medical College, Kolkata, India
4
Department of Microbiology, NRS Medical College, Kolkata, India
Abstract
Background: In this study, 76 male patients aged between 18 and 61 years affected with Tinea
cruris attending the outpatient department of NRS Medical College during a 1-year period were
selected. Materials and Methods: The patients were divided into two groups as Regimen I (n
37) and Regimen II (n 39) who were treated with Terbinafine (gr I) cream and Butenafine (gr II)
cream, respectively. Results: The predominant pathogen was found to be Trichophyton rubrum
in 99% of cases. Mycological cure, overall cure and effective treatment were evaluated on 7, 14
and 42 days. Conclusions: From the study, it was found that Butenafine produced the quickest
result and primary efficacy end points were much higher with Butenafine cream than that of
Terbinafine cream and this difference was statistically significant (P < 0.01).
Keywords: Tinea cruris, butenafine cream, terbinafine cream
How to cite this article:
Das S, Barbhuniya J N, Biswas I, Bhattacharya S, Kundu P K. Studies on comparison of the
efficacy of terbinafine 1% cream and butenafine 1% cream for the treatment of Tinea cruris.
Indian Dermatol Online J 2010;1:8-9
How to cite this URL:
Das S, Barbhuniya J N, Biswas I, Bhattacharya S, Kundu P K. Studies on comparison of the
efficacy of terbinafine 1% cream and butenafine 1% cream for the treatment of Tinea cruris.
Indian Dermatol Online J [serial online] 2010 [cited 2015 Jan 11];1:8-9. Available
from: http://www.idoj.in/text.asp?2010/1/1/8/73249

abstrak
Latar Belakang: Dalam penelitian ini, 76 pasien laki-laki berusia antara 18 dan 61
tahun yang terkena dengan Tinea cruris menghadiri departemen rawat jalan NRS
Medical College selama periode 1 tahun yang dipilih. Bahan dan Metode: Pasien
dibagi menjadi dua kelompok sebagai rejimen I (n 37) dan rejimen II (n 39) yang
diobati dengan Terbinafine (gr I) krim dan Butenafine (gr II) krim, masing-masing.
Hasil: patogen dominan ditemukan Trichophyton rubrum dalam 99% kasus.
Menyembuhkan mikologi, menyembuhkan secara keseluruhan dan pengobatan
yang efektif dievaluasi pada 7, 14 dan 42 hari. Kesimpulan: Dari penelitian,
ditemukan bahwa Butenafine menghasilkan hasil tercepat dan poin utama
keberhasilan akhir yang lebih tinggi dengan Butenafine krim daripada krim
Terbinafine dan perbedaan ini bermakna secara statistik (P <0,01).