Professional Documents
Culture Documents
10062412
Course lecturers
Dr. Samy Hammady, M.D.; Samihammadi2000@yahoo.com.
Tel: (02) 5270000 Ext 4149.
Dr. Layla Borham, M.D. borhaml@hotmail.com.
Tel: (02) 5270000 Ext 4273
Department of Pharmacology and Toxicology
Faculty of Medicine
Umm Al-Qura University
When you have questions, concerns, or suggestions, please contact Dr. Samy Hammady, for male
section or Dr. Layla Borham, for female section by e-mail, call for an appointment, or catch them
before or after class or lab.
Lectures
Each lecture is accompanied by a PowerPoint presentation. Information from the presentation and
assigned reading is important for mastering the learning objectives which are the primary focus
of exam questions.
Review Sessions
Review sessions will be scheduled prior to each exam. The time and format for each session will
be arranged via the students coordinators.
Course Objectives:
- On completion of the course, students will be able to:
Provide a sound knowledge of the actions of many important groups of drugs used in medicine.
Acquaint with the pathogenesis of cardiovascular disorders.
Demonstrate knowledge of the pharmacodynamics, pharmacokinetics therapeutic uses and
adverse effects of drugs used for treatment of hypertension, angina, heart failure, and
arrhythmia.
Acquaint students with pharmacodynamics, pharmacokinetics, clinical uses and adverse effects
of drugs used in the treatment of central nervous system disorders.
Demonstrate knowledge regarding the pharmacology of non steroidal anti-inflammatory drugs
and drugs used to treat gout.
Provide
students
with
information
concerning
chemistry,
pharmacological
effects,
4. Compose thoughtful and fair exam questions that assess student learning and application of
the course content.
5. Directing the case sessions and facilitators to provide an effective learning experience in
small group, team-oriented sessions.
6. Providing answers and explanations to student inquiries regarding any aspect of the course.
7. Providing advice and assistance to students for improving their learning strategies and
performance in the course.
8. Reviewing and implementing appropriate changes in the course based on student feedback
and evaluations.
Learning Resources
Required Textbook:
1- Basic and Clinical Pharmacology, (2006) 10th edition, Bertram G. Katzung. McGraw-Hill
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2- Lippincott's Illustrated Reviews: Pharmacology (2005) 3rd edition. Mary J Mycek, Richard
A Harvey, Pamela C Champe.
o Third Edition enables rapid review and assimilation of large amounts of complex information
about the essentials of medical pharmacology.
o Pharmacology features an outline format, over 500 full-color illustrations, cross-references to
other titles in the series, and over 125 review questions.
o New and expanded material on steroid hormones, poisons, drugs for obesity, osteoporosis,
erectile dysfunction, anti-inflammatory drugs, and autacoids.
o Innovative Concept Maps, a tool for visualizing the connections between concepts.
o Material is represented in a hierarchical fashion with the most general concepts at the top of
the map and the more specific, less general concepts arranged beneath.
o End of Chapter Summaries of the most important/clinically significant testable information.
Course evaluation
There will be three quizzes, seminar and clinical case presentations, and theory exams for each
semester, and the questions will focus on the learning objectives, students are expected to master
from material presented in the lectures and textbook.
The format of the examinations will typically include multiple-choice questions with one best
answer, short essay questions, and clinical cases.
Quiz 1 (in week 5) covers material from Lecture 1 through 4.
Quiz 2 (in week 9) covers material from Lecture 5 through 8.
Quiz 3 ( in week 13) covers material from Lecture 9 through 12.
Course content:
Major Topics of the course:
A. Drugs acting on the cardiovascular system (10 hours).
B. Drugs acting on the central nervous system (11 hours).
C. Endocrine pharmacology (9 hours).
D. Chemotherapy (12 hours).
Detailed Contents:
First Semester
Week
No
Clinical case
discussion
Topic
Notes
Hypertension
Ischemic heart
diseases
Heart failure
First
periodic
exam
(10 marks)
(week 1week 4)
Introduction
- Neurotransmitters in the brain, their anatomic
distribution, function and disorders resulting from
deficit or excess.
Epilepsy
10
11
12
13
Second
periodic
exam
(10 marks)
(week 5week 8)
Psychopharmacology
- Types of psychosis
- Depression and antidepressant drugs
- Schizophrenia, mania and neuroleptic drugs.
- Lithium.
Parkinsonism and drugs used in management
- Pathophsiology of Parkinsonism
- Classification of antiparkinsonial drugs
- Optimization of L-dopa therapy.
Narcotic analgesics
- Pathophsiology of pain.
- Morphine receptors.
- Classification of narcotic analgesics.
- Detailed study of narcotic analgesics.
- Drug addiction, withdrawal syndrome and treatment
Nonsteroidal anti-inflammatory drugs and Gout
- The inflammatory response.
- Detailed study of NSAIDs.
- Pathogenesis of gout.
- Drugs used for treatment of gout.
10
Hallocinogens
and CNS
stimulants abuse
Third
periodic
exam
(10 marks)
(week 10week 12)
14
Parkinsonism
Local anesthetics
- Modes of the sodium channels.
- Detailed study of local anesthetics
15, 16
17, 18
Second Semester
Week
No
Clinical case
discussion
Topic
A. Endocrine pharmacology:
1
Parathyroid hormones.
Agents that affect bone mineral homeostasis.
Calcium homeostasis and treatment of osteoporosis.
Suprarenal cortical hormones and abnormalities
Corticosteroids: uses and adverse effects
- Pancreatic hormones
- Insulin
- Oral antidiabetic agents
Hypo-function
of pituitary gland
Hyper-function
of pituitary gland
Hypothyroidism
11
Notes
First
periodic
exam
(10 marks)
(week 1week 4)
B. Chemotherapy:
Hyperthyroidism
10
11
12
13
14
15, 16
17, 18
DM Type I
Second
periodic
exam
(10 marks)
(week 5week 8)
DM Type II
Antiprotozoal drugs
- Antiamoebics , antileishmania , antitrypanisoma.
- Drugs for guirdiasis, trichmoniasis, and Plasmodium.
Anthelminthic agents.
- Parasitic nematodes
- Parasitic trematodes
- Parasitic cestodes
- Antiviral drugs.
- Antifungal drugs.
Hypo-function of
suprarenal gland
Third
periodic
exam
(10 marks)
(week 10week 12)
Hyper-function
of suprarenal
gland
12