You are on page 1of 12

REPBLICA DEMOCRTICA DE TIMOR-LESTE

MINISTRIO DA SADE

Ministrio

da Sade

DAFTAR OBAT ESSENSIAL NASIONAL


TIMOR-LESTE
(DOENTL)

Edisi Revisi ke-3 Januari 2010


UNTUK RUMAH SAKIT REFERAL-CHC DISTRIK DAN SUB DISTRIKHEALTH POST DI TIMOR-LESTE

DEPARTEMENTO SERVIOS FARMACUTICOS

Mi

da nist
Sa rio
d
e

Daftar Obat Essensial Nasional untuk Fasilitas Kesehatan tingkat Dasar


dan Rumah Sakit Rujukan
Daftar obat Essensial Timor-Leste telah direvisi dari edisi tahun 2004. Revisi ini telah dilakukan

Sodium fluoride

in any available formulation to prepare solution

dengan melibatkan para dokter dan professional kesehatan yang dikoordinir oleh Departemen

Thiamine

Tablet 50mg

Farmasi Kementrian Kesehatan.

Vitamin B1; thiamine

Tablets 50 mg

Vitamin A retinol

Capsule: 50 000 IU; 100 000 IU; 200 000 IU (as palmitate).
Oral oily solution:
100 000 IU (as palmitate)/ml in multidose
dispenser.

Tablet
(sugar coated): 10 000 IU (as palmitate).
Water miscible injection: 100 000 IU (as palmitate) in
2 ml ampoule.

Vitamin B12, hydroxocobolamine

Injection: 1 mg in 1 ml ampoule.

Vitamin D3; ergocalciferol

Tablet or capsule, 1.25 mg (drisdol).

Seleksi DOEN ini didasarkan pada criteria umum WHO, adapun criteria yang didaftarkan adalah
sebagai berikut :
1. Didasarkan pada eksistensi pola penyakit yang ada di Timor-Leste
2. Menurut bukti dan dokumentasi efektifitas dan keamanan/factor resiko
3. Ketersediaan product dengan qualitas yang baik
4. Rasio harga yang terjangkau

Vitamin K (Phytomenadione - see under blood)

5. Preferensi pengetahuan yang baik dan dokumentasi obat yang baik

6. Produk tunggal kecuali untuk program malaria,TBC dan HIV/AIDS


7. Seleksi menurut nama generic atau INPN untuk dapat mempermuda pengantian dengan
qualitas dan pengadaan dengan harga yang baik.
DOEN baru ini perlu digunakan untuk perencanaan pengadaan,supply dan penggunaan klinis
dari obat. Pemakai DOEN adalah SAMES, Distributor farmasi, pelayan kesehatan dan institusi
kesehatan lain di Timor-Leste.
Konsultasi DOEN ini juga telah dilakukan dengan mengirimkan draft dan menerima komentar,
saran dan masukan dari para medis/dokter di Rumah Sakit Nasional (HNGV Dili), Hospital Referal
dan dari beberapa dokter di fasilitas pelayan kesehatan dasar (CHC Distrik).
Seleksi DOEN ini juga dilakukan dengan melalui seminar dan diskusi tentang revisi Panduan atau
Standar Pengobatan Nasional/STGs.
DOEN baru untuk Timor-Leste ini diutamakan untuk fasilitas pelayanan kesehatan dasar (HP,
CHC Distrik dan CHC sub distrik) dan Rumah Sakit Referal atau Hospital Referrals. Dan daftar obat
tambahan untuk para dokter specialist dalam proses penyusunan khusus untuk HNGV-Dili.
Dili, April; 2010
Disetujui oleh
Agapito da Silva Soares
Director Geral Ministerio da Saude Timor-Leste
i

16

Kementrian Kesehatan Timor Leste mengucapkan Terima kasih kepada para pihak yang
telah berkontribusi terhadap penyusunan DOEN untuk Timor-Leste edisi ke-3 tahun 2010

21.5 Miotics and antiglaucoma medicines


Acetazolamide

Tablet: 250 mg.

Pilocarpine

Eye drops: 0,5%, 2%; 4% (HCL or Nitrate) 5ml

Timolol maleate

Solution (eye drops): 0.5% (as maleate). 5ml

Atropine sulphate

Solution (eye drops); 1% Bottles 3ml

Epinephrine (adrenaline)

Solution (eye drops): 2% (as hydrochloride).

Tropicamide

Eye drops 0,5%, and 1%, 5ml

21.6 Mydriatics

antara lain:
1.Komisi Revisi STG /EDL antara lain : Dr.Salma Sagran (AMTL), Dr.Cesaltino Leao (DG
Baucau),Sr.Delfim da Costa X.Ferreira,MPH , (Departemen Farmasi), Sr.Antonio Ximenes
(Departemen Farmasi), Sr.Gil da Costa (ex.DG SAMES), dr.Ana Magno (DNSHE), dr.Odete
Viegas (HNGV Dili), dan dr.Santina Gomes (HNGV-Dili).
2.Para pemegang program kesehatan di Ministerio da Saude : IMCI, MCH, Malaria,
HIV/AIDS, Lepra, Filariasis, Mental, Dental dan lainnya.
3.Tim Medis HNGV Dili : dr.Terlinda (Director Klinik) dan tim dokter Timor-Leste, tim dokter

21.5. ENT PREPARATIONS


Oxylometazolin

Nasal drops 0,1%, 10mL adult, and 0,05% pediatric, 10mL

Phenylephrine

Nasal drops 0,1%

Boric acid/ Spirit (E)

Solution 2%

Chlorhexidine Cream 0.1%

Cream 0,1%

Polymyxin+Bacitracin

Ointment 5000 Units + 400 Units

Neomycin

Powder 5%

Ear drops 5%, 10%

Sodium bicarbonate with glycerine for ear way


softening
Cavities packing material; Bismuth subnitrate
and iodoform

x
x

Paste 30g/sachet

22. OXYTOCICS AND ANTIOXYTOCICS


22.1 Oxytocics

dari Cuba,China,Australia, Filipina,Indonesia dan PNG.

Ergometrine

Injection, 200 microgram (hydrogen maleate) in 1-ml ampoule

Oxytocin

Injection, 10 IU in 1-ml ampoule, to be prepared as 2.5 Intl units in 500ml of normal saline or
dextrose

Misoprostol

Vaginal tablet, 25 and 200 microgram scored tablet

Nifedipine

Immediate release capsule: 10 mg.

Salbutamol

See STG Reproductive health, Tocolytics

5. Tim medis Hospital Referal Baucau : dr. Zelia dos Santos (Director Clinica)dan semua tim

Glyceryltrinitrate

See STG Reproductive health, Tocolytics

dokter HR Baucau

Intraperitoneal dialysis solution

4.Tim Medis Spesialist HNGV Dili : dr.Virna Gusmao,Sp Pediatria, dr.Artur Cortereal,SP
internist, dr.Romaldo Bosco,SPOG, dr.Mendes Pinto,SPB, dan dr.Rogerio Pedro Sam,SPOG
dan dr.Aniceto Barreto,SPA.

22.2 Antioxytocics (tocolytics)

23. PERITONEAL DIALYSIS SOLUTION


Parenteral solution

24. PSYCHOTHERAPEUTIC MEDICINES


24.1 Medicines used in psychotic disorders

6. Tim Medis Hospital Referal Suai : dr. Julia Magno dan tim dokter HR Suai

Benztropin for control of dystonic adverse


reactions esp after Haloperidol

See as listed under section Antiparkinson medicine (tablet, 2mg as mesylate, injection 1mg/ml, in 2
ml ampoule)

Chlorpromazine

Tablet: 25 mg, 50mg and 100 mg (hydrochloride).. Injection: 25 mg (hydrochloride)/ml in 2


ampoule., Oral liquid: 25 mg (hydrochloride)/5 ml.

8. Tim SAMES : Sr. gil da Costa, Sr. Antonio Oqui dan Sr. Theodoro de Jesus

Haloperidol

Tablet: 1,5 mg, 2 mg; and 5 mg both scored, Injection: 5 mg in 1


2mg/mL

9. semu pihak yang telah memberikan konstribusi dalam penyusunan DOENTL ini.

24.2 Medicines used in mood disorders


24.2.1 Medicines used in depressive disorders
x

7. Tim Medis Hospital Referal Maliana : dr. Vitorino Talo dan time dokter HR Maliana.

Amitriptyline

ml

ml ampoule. Oral liquid 1mg,

Tablet: 25 mg (hydrochloride).

24.2.2 Medicines used in bipolar disorders


Carbamazepine

Tablet (scored): 100 mg; 200 mg.

Valproic acid

Tablet (enteric coated): 200 mg (sodium valproate).

24.2.3 Medicines used in generalized anxiety and sleep disorders


Diazepam

Tablet (scored): 2 mg; 5 mg.

24.2.4 Medicines used for obsessive compulsive disorders and panic attacks
Clomipramine

Capsule: 10 mg; 25 mg (hydrochloride).

24.5 Medicines used in heroine detoxification programmes

iii

Methadone

Concentrate for oral liquid: 5 mg/ml; 10 mg/ml (hydrochloride).

Clonidine

See also listed as coanalgesic

14

DEFINISI TEKNIS :

25. OBAT-OBAT GANGGUAN SALURAN PERNAPASAN


25.1 Antiasthmatic and for chronic obstructive pulmonary disease
Beclometasone

Inhalation (aerosol): 50 micrograms per dose; and; 250 micrograms (dipropionate) per dose.

Budesonide (inhalation corticosteroid for


childrem, minimal growth retardation)

Inhalation,50 microgram. 200 microgram per dose with metered dose inhalator spray

Epinephrine (adrenaline)

Injection: 1 mg (as hydrochloride or hydrogen tartrate) in 1

Ipratropium bromide

Inhalation (aerosol): 20 micrograms/metered dose.

S-NP dan artinya sebagai berikut :

Inhalation spacer for asthma inhalation


metered dose inhalator with aerosol spray

Peak airflow meter (PEF meter)

ml ampoule.

Inhalation (aerosol): 100 micrograms (as sulfate) per dose. Metered dose inhaler (MDI)
Injection: 50 micrograms (as sulfate)/ml in 5
ml ampoule.
Oral liquid: 2 mg/5 ml.
Respirator solution for use in nebulizers: 5 mg (as sulfate)/ml.
Tablet: 2 mg; 4 mg

Salbutamol

DOEN adalah memuat obat-obatan yang diseleksi dengan beberapa klasifikasi : V-E-NV; Vital adalah supply dan harus disediakan sebagai cadangan penyelamatan/keamanan, ini
untuk menjamin resiko dari stockout. Jika dalam waktu singkat tidak tersedia obat yang
diklasifikasi V ini maka akan menimbulkan konsequensi serius.
E; Essensial, Adalah obat-obatan yang harus teresedia setiap saat dan setiap hari

Theophylline

theophylline tablets 100 mg and 200 mg slow release. ONLY FOR SEVERE TREATMENT
RESISTANT ASTHMA

N; Necessary/dibutuhkan, Adalah obat-obatan penting tapi menurut klasifikasi pengobatan ini

Aminophylline

injection, 25 mg/ml ampoule with 10 ml ONLY FOR SEVERE TREATMENT RESISTANT ASTHMA,
NOT FIRST LINE DUE TO ARRHYTMIA RISK

dapat ditunda atau dimulai beberapa hari setelah didiagnosis untuk diadakan pengobatan.
S; Specialist medicine, adalah obat-obatan yang hanya digunakan menurut resep dari dokter

26. WATER, ELECTROLYTE AND ACID-BASE BALANCE and PARENTERAL NUTRITION


26.1 Oral
ORS Oral Rehydration solution

See Section 17; Oral Rehydration Solution (ORS) according to updated IMCI recommendation

Zinc tablets

According to IMCI guidelines

Potassium chloride tablets

Tablets; 600 mg slow release tablets for per oral solution.

NP; Distribusi tergantung kepada permintaan program nasional.

DOEN ini adalah daftar obat-obatan utama yang harus tersedia untuk sistim pelayanan

26.2 Parenteral
Mannitol

Solution for infusion 20%, in 500 ml

Calcium gluconate

Injection: 100 mg/ml in 10 ml ampoule (10%)

Calcium Chloride

Injection 100 mg/mL

Glucose (dextrose)

(NB 10% needed for pediatric

cases)

Injectable solution: 5%; 10% isotonic; 50% hypertonic, 50 ml vial

Glucose with sodium chloride

Injectable solution: 4% glucose, 0.18% sodium chloride, (equivalent to Na+ 30 mmol/l, Cl


mmol/l).

Potassium chloride

Solution: 11.2% in 20

ml ampoule (equivalent to K+ 1.5 mmol/ml, Cl

diperlukan.

Dalam daftar tambahan DOEN, obat-obat pelengkap/complementary juga disusun hanya untuk
pemakaian Spesialist daftar obat ini untuk penyakit-penyakit tertentu,yang berasal dari

30

1.5 mmol/ml).

20 ml ampoule Injectable solution: 1.4% isotonic (equivalent to Na+ 167 mmol/l,HCO3


167 mmol/l).
Solution: 8.4% in 10 ml ampoule (equivalent to Na+ 1000 mmol/l, HCO3
1000 mmol/l).

Sodium chloride NaCl Solution 0,9%

Infusion solution 0,9% 1L with infusion drip-set

sodium lactate, compound solution (Ringer


Lactate)

Injectable . infusion solution 500 ml and 1L, each with drip-set

Ampoule 2 mL, 5 mL, 10 mL

26.3 Miscellaneous
Water for injection

kesehatan dasar. Criteria penyusunan daftar obat ini adalah diseleksi paling efektif,aman dan
harga murah, dan sebagai obat-obata yang paling efefectiv dalam kondisi-kondisi yand

Sodium bicarbonate 8,40%

specialist

27. VITAMINS, MINERALS DAN NUTRISI

diagnosis khusus atau kondisimedical lain yang dibutuhkan.


Penyusunan DOEN ini dibuat tidak secara otomatis sudah menjamin qualitas produk-produk

Ascorbic acid

Tablet 50mg

Calcium carbonate

Tablets 500 mg

Calcium gluconate

Injection 100 mg/ml in 10 mL ampoule

Ergocalciferol

Capsule or tablet: 1.25 mg (50 000 IU).


Oral liquid: 250 micrograms/ml (10 000 IU/ml).

Folic acid

Tablet 1mg and 5 mg

nama dagang atau nama patent yang berbeda-beda.

Iodine

Capsule: 200 mg.


Iodized oil: 1 ml (480 mg iodine); 0.5 ml (240 mg iodine) in
ampoule (oral or injectable); 0.57 ml (308 mg iodine) in dispenser
bottle.

Ini adalah tanggungjawab sistim pengadaan produk farmasi,distributor nasional atau otoritas

Iron Ferrous salt 60 mg Fe, w/wo Folic acid

Tablet 200 mg Ferrous salt corresponding to 60 mg Fe, And; Ferrous sulphate 200 mg +400
microgram folic acid, And; Syrup Ferrous sulphate 125 mg salt/ml; equivalent to 25 mg iron per ml

Multivitamin tablets

Tablets

Nicotinamide

Tablet 50mg

Vitamin B6; pyridoxine

tablet 50 mg

Plumpy Nuts

Nutrition program

Riboflavin

Tablets 5mg

farmasi tapi sebagai prinsip utama bahwa obat-obatan ini disusun dengan nama
generic.Ketersedian obat-obatan dalam DOEN ini tersedia di pasaran internasional tapi dengan

pengawas local untuk melakukan metode evaluasi agar menjamin semua obat-obatan yang
diimport,didaftarkan, dan pengawasan obat-obatan yang dijual dengan nama dagang di pasaran
di Timor-Leste sesuai dengan qualitas produksi. Juga tanggung jawab apotek-apotek dan klinikklinik untuk menjaga dan menyediakan obat-obat yang berkualitas.
e

15

iv

DAFTAR HALAMAN;

18.5. Progestogens
Norethisterone
Medroxyprogesterone

Tablet 5mg
Tablet 5mg

18.6 Insulins and other antidiabetic agents


Glibenclamide

Tablet: 2.5 mg; 5 mg. scored tablets

Insulin human soluble short-acting

Injection: 40 IU/ml in 10 ml vial; 100 IU/ml in 10 ml vial.

InsuliI human intermediate acting

Injection: 40 IU/ml in 10 ml vial; 100 IU/ml in 10 ml vial (as compound insulin zinc suspension or
isophane insulin).

Metformin

Tablet: 500 mg (hydrochloride).

18.7 Thyroid hormones and antithyroid medicines


Levothyroxine

Tablet: 50 micrograms; 100 micrograms (sodium salt).

Potassium iodide

Tablet 60mg

Propylthiouracil

Tablet 50mg

Injection.

19. IMMUNOLOGICALS
19.1 Diagnostic agents
Tuberculin, purified protein derivative (PPD)

19.2 Sera and immunoglobulins


Antivenom immunoglobulin*

Detailed specifications to be tailored to local venoms

Diphtheria antitoxin

Injection: 10 000 IU; 20 000 IU in vial.

Rabies immunoglobulin

Injection: 150 IU/ml in vial.

19.3 Immunization
EPI- BCG Vacine + diluent

Ampule/ 20 dose

EPI - DPT+ Hepatitis B Vaccine absorbed +


diluent

Vial/10 dose

EPI - Measles Vaccine + diluent

Vial/10 dose

EPI - OPV Vaccine

Vial/10 dose

EPI - TT Tetanus toxoid Vaccine-absorbed

Vial/10 dose

Hepatitis B

Single dose

20. MUSCLE RELAXANTS. This section has been moved to the section about anaesthetics
21. OPHTHALMOLOGICAL and ENT PREPARATIONS
21.1. Eye drops diagnostic and lubricant
Fluorescein strips 100 box

100 strip box

Lubricant eye drops

Artificial tear solution

21.2 Anti-infective agents


Aciclovir

Ointment: 3% tube 4,5 gram

Chloramphenicol

Eye Ointment 1%, also for the ear, 5 gram tube, And; 0,5% eyedrops, 5mL

Erythromycin

Eye ointment 0,5%, 2,5 g

Gentamicin

Solution (eye drops): 0.3% (sulfate), 5ml

Tetracycline

Eye ointment 1 %, 5g tube

Tetracycline + Cortizone

Eye drops 0,5%, 5ml

Tobramycin + dexamethazone

Eye drops, tobramycin 0,3%, dexamethazone 0,1%; 5ml.

21.3 Anti-inflammatory agents


Prednisolone Na phosphate

Solution (eye drops): 1%, bottle 5ml

Dexamethazone

Eye drops 1%, bottle 5 ml

21.4 Local anaesthetics


Tetracaine

Solution (eye drops): 0.5% (hydrochloride). 10ml

13

JUDUL,

HALAMAN

1. ANESTESI
1.1. General Anesthetics
1.2. Muscle relaxants (peripherally acting) and cholinesterase inhibitors
1.3. Local anesthetics
1.4. Preoperative medication and sedation for short-term procedures

2 . A N T I N Y E R I , A N T I P I R E T I K , N S A I D S d a n R E M AT I K
2.1 Non-opioids and non-steroidal anti-inflammatory medicines (NSAIDs)
2.2. Opioid analgesics
2.3. Medicines for treatment of gout
2.4 Disease modifying agents used in rheumatoid disorders (DMARDs)

3 . A N T I A L L E R G I C S D A N O B AT- O B ATA N A N A P I L A N S I S D A N S H O K
3.1. Corticosteroids
3.2. Medicine for management of shock

4.ANTIDOTUM
5. ANTICONVULSANTS - ANTIEPILEPTICS
6 . O B AT A N T I I N F E K S I
6.1 Anthelminthics
6.1.1 Intestinal anthelminthics
6.1.2 Antifilarials, antischistozomal anti trematode
6.2. For ectoparasites
6.2 Antibacterials
6.2.1 Beta Lactam medicines
6.2.2 Other antibacterials
6.2.3 Antileprosy medicines (distributed according to national
program np)
6 . 2 . 4 . Tu b e r c u l o s i s ( d i s t r i b u t e d a c c o r d i n g t o n a t i o n a l
program np)
6.2.4.1. Anti tuberculosis fixed drug combinations
6.3 Antifungal medicines
6.4 Antivirals
6.4.1 Antiherpes medicines
6.4.2 Antiretrovirals
6.4.2.1 Nucleoside reverse transcriptase inhibitors (distributed
according to national program np)
6.4.2.2 Non-nucleoside reverse transcriptase inhibitor (distributed
according to national program np)
6.4.2.3 Protease inhibitors (distributed according to national
program np)
6.4.2.3.1. Supplementary list with available fixed combinations
(distributed according to national program np)
6.4.2.3.2 Fixed combinations to prevent mother-to-child transmission
(distributed according to national program np)
6.5 Antiprotozoal medicines
6.5.1 Antiamoebic and antigiardiasis medicines
6.5.2 Antimalarial medicines (distribution to follow according to
national program updates np)
6.5.2.1 For curative treatment
6.5.2.2 For malaria-prophylaxis
6.5.3 Antipneumocystosis anti toxoplasmosis medicines

3
3
3.3

7. OBAT-OBAT ANTIMIGRAN
7.1 For treatment of acute attack
7.2 For prophylaxis
8. ANTINEOPLASTIC, IMMUNOSUPPRESSIVE MEDICINES AND
MEDICINES FOR PALLIATIVE CARE.
These medicines will be procured after preparation of an additional
selection matching with current protocols at the National Hospital.

7.1

17.7 Obat-obat Diare

Oral rehydration salt powder for 1L, 27,9 g


salts

8.1 Immunosuppressive medicines


8.2.1. A. Cytotoxic medicines and antihormones.
Supply of these medicines will be defined in a separate list for
procurement, defined at the National Hospital.

10. OBAT-OBATAN GANGGUAN PARAH


10.1 Anti-anaemia medicines
10.2. Medicines affecting coagulation
11. BLOOD PRODUCTS AND PLASMA SUBSTITUTES
All supply of blood products and plasma fractions must comply with
the WHO Requirements for the Collection, Processing and Quality
Control of Blood, Blood Components and Plasma Derivatives
(WHO Tech. Report Series, No. 840, 1994, Annex 2).

Zinc sulfate. According updated IMCI


protocol, for acute diarrhoea zinc sulfate in 10
mg per unit dose (tablet or oral liquid) should
be used as an adjunct to oral rehydration
salts.
8.1

Tablet: in 10 mg per unit dosage forms. Oral liquid: in 10 mg per unit dosage forms.

13. OBAT-OBATAN DERMATITIS (JEDIAAN TROPICAL)


13.1 Antifungal medicines
13.2 Anti-infective medicines
13.3 Anti-inflammatory and antipruritic medicines
13.4 Medicines affecting skin differentiation and proliferation
13.5 Scabicides and pediculicides
14. DIAGNOSTICS
14.1 Ophthalmic medicines
14.2 Radiocontrast media

16. OBAT-OBAT DIRIRETIK (SALURAN KEMIH)


17. OBAT-OBAT PENCERNAAN GASTROINTESTINAL
17.1 Antacids and other antiulcer medicines
17.2 Antiemetic medicines
17.3 Antihaemorrhoidal medicines
17.4 Anti-inflammatory medicines

18. HORMON DAN OBAT-OBAT ENDOKRIN DAN KONTRASEPSI


Addisons disease is rare; adrenal hormones are included elsewhere in this EML

18.3 Kontrasepsi
18.3.1 Oral hormonal contraceptives
ethinylestradiol + levonorgestrel

Tablet: 30 micrograms + 150 micrograms.

ethinylestradiol + norethisterone

Tablet: 35 micrograms + 1.0 mg.

levonorgestrel

Tablet: 30 micrograms; 750 micrograms (pack of two); 1.5 mg.

Progesterone Only Oral Contraceptives


(POPS)

Per oral tablets containing progestin only -available brand: Ovrette-28 (Norgestrel 0.375mg)

9.1

10

medroxyprogesterone acetate

Depot injection: 150 mg/ml in 1

ml vial.

medroxyprogesterone acetate + estradiol


cypionate

Injection: 25 mg + 5 mg

norethisterone enanthate

Oily solution, 200 mg/ml in 1-ml ampoule

Microgynon / COC Pills

0.03 mg/0.15 mg

Levenorgestrel Implants (Jadelle or Norplant


or similar) (10 set/6imp.)

0,03 mg/0,15 mg 10 set / 6 implants

I.U.D. Insertion kits (multiload)

UNFPA kit

Norplant insertion and removal

UNFPA kit

Ovrette (Norgestrel only)

Tablets 0,075 mg

POP (Levonorgestrel)only

0,03 mg 3 cycles in blister pack

10.1

18.3.3. Barrier methods


Condoms

15. DISINFECTANTS DAN ANTISEPTICS


15.1 Antiseptics
15.2 Disinfectants

18.1 Adrenal hormones and synthetic substitutes


8.1

18.3.2. Injectable hormonal contraceptives

12. OBAT-OBAT JANTUNG (CARDIOVASLUGAR)


12.1 Antianginal medicines
12.2 Antiarrhythmic medicines
12.3 Antihypertensive medicines
12.4 Medicines used in heart failure
12.5 Antithrombotic and fibrinolyitc medicines

+ trisodium citrate dihydrate may be replaced by sodium


hydrogen carbonate (sodium bicarbonate) 2.5 g/l. However, as the
stability of this latter formulation is very poor under tropical
conditions, it is only recommended when manufactured for
immediate use.

8.2.1. B. Hormones and antihormones in antineoplastic care


All hormones for management of neoplasia will be listed and
procured under specialist order from National hospital
9. OBAT-OBAT ANTI PARKINSON

glucose: 75 mEq
sodium: 75 mEq or mmol/l
chloride: 65 mEq or mmol/l
potassium: 20 mEq or mmol/l
citrate: 10 mmol/l
osmolarity: 245 mOsm/l
glucose: 13.5 g/l
sodium chloride: 2.6 g/l
potassium chloride: 1.5 g/l
trisodium citrate dihydrate+: 2.9 g/l

11

18.3.4 Intrauterine and implantable devices


Cupper containing device

Levonorgestrel releasing implant

Two rod levonorgestrel releasing implant, each rod containing 75 mg of levonorgestrel (150 mg
total). See 18.3.2. above

18.4 per oral estrogen and progestogen contraceptives


11.1

11.2

Ethinylestradiol

Tablet 10 microgram, 50 microgram See 18.3.1. above

Combined Oral Contraceptives (COCs)

Blister pack with per oral pills containing both estrogen and progesterone packed per cycle. See
18.3.1. above

Estriol crme

Intravaginal crme 0,10 %

12

15. DISINFECTANTS AND ANTISEPTICS


15.1 Antiseptics
Chlorhexidine gluconate solution

5%, glycerine-based

Ethanol

70%, 1L

Polyvidone iodine

10% 1L

Povidone iodine, surgical scrub

7,50%

15.2 Disinfectants
Chlorine base compound

hypochlorite solution 5%. 1 Litre bottle.

Chlorine sodium dichloroisocyanurate

1,67 g

Glycerine BP

80%

Surgical alcohol, isopropanol

70%

16. OBAT-OBAT SALURAN KEMIH (DIURETIK)


Amiloride

Tablet: 5 mg (hydrochloride).

Furosemide

Tablet, 40 mg; injection, 10 mg/ml in 2-ml ampoule

Hydrochlorothiazide

Tablet: 25 mg. Should be possible to split since optiomal antihypertensive dose is 12,5 mg / day

Mannitol

Injectable solution: 10%; 20%.

Spironolactone

Tablet: 25 mg.

17. OBAT-OBAT ANTI EMETIK


17.1 Antacids and other antiulcer medicines
Aluminium hydroxide

Oral liquid: 320 mg/5 ml.


Tablet: 500 mg.

Bismuth subsalicylate

According to Gastrointestinal Treatment Guidelines

Ranitidine

Injection: 25 mg/ml in 2 ml ampoule.


Oral liquid: 75 mg/5 ml.
Tablet: 150 mg (as hydrochloride).

Magnesium hydroxide

Oral liquid: equivalent to 550 mg magnesium oxide/10 ml.

17.2 Antiemetic medicines


Metoclopramide

Injection 10 mg in 2 ml (5mg/ml) ampoule. Tablet: 10 mg

Promethazine

Injection: 50 mg (hydrochloride)/ml in 2
Oral liquid: 5 mg (hydrochloride)/5 ml.
Tablet: 10 mg; 25 mg (hydrochloride).

Multivitamin combination for hyperemesis in


pregn

Ascorpic acid 500mg, anhyderus glucose 1g, nicotinamide 160mg, pyridoxine hydrochloride 50mg,
riboflavin 4mg, thiamine hydrochloride 250mg/10ml

Creme 2%

17.4 Obat-obat anti Inflamasi


Sulfasalazine

Retention enema.
Suppository: 500 mg.
Tablet: 500 mg.

Hydrocortisone

Retention enema.
Suppository: 25 mg (acetate).

17.5 Antispasmodic medicines


Hyoscine butylbromide

18. HORMON OBAT-OBAT ENDOKRIN DAN KONTRASEPSI


18.1 Adrenal hormones and synthetic substitutes
18.3 Contraceptives
18.3.1 Oral hormonal contraceptives
18.3.2. Injectable hormonal contraceptives
18.3.3. Barrier methods
18.3.4 Intrauterine and implantable devices
18.4 per oral estrogen and progestogen contraceptives
18.5. Progestogens
18.6 Insulins and other antidiabetic agents
18.7 Thyroid hormones and antithyroid medicines
19. IMMUNOLOGICALS
19.1 Diagnostic agents
19.2 Sera and immunoglobulins
19.3 Immunization
20. MUSCLE RELAXANTS. This section has been moved to the
section about anaesthetics
21. OPHTHALMOLOGICAL and EAR-NOSE-THROAT (ENT) MEDICINES
21.1. Eye drops diagnostic and lubricant
21.2 Anti-infective agents
21.3 Anti-inflammatory agents
21.4 Local anaesthetics
21.5 Obat-obat THT
21.6 Mydriatics

12

13

13.1

13.2

21.5. Ear-Nose-Throat (ENT) MEDICINES


22. OXYTOCICS AND ANTIOXYTOCICS
22.1 Oxytocics
22.2 Antioxytocics (tocolytics)

14

ml ampoule.

17.3 Antihaemorrhoidal medicines


Lidocaine containing crme

17.5 Antispasmodic medicines


17.6 Laxatives
17.7 Medicines used in diarrhoea

Injection 20 mg/ml ampoule 1 ml. Tablets 10mg

23. PERITONEAL DIALYSIS SOLUTION


24. PSYCHOTHERAPEUTIC MEDICINES
24.1 Medicines used in psychotic disorders
24.2 Medicines used in mood disorders
24.2.1 Medicines used in depressive disorders
24.2.2 Medicines used in bipolar disorders
24.2.3 Medicines used in generalized anxiety and sleep disorders
24.2.4 Medicines used for obsessive compulsive disorders and panic attacks
24.5 Medicines used in heroine detoxification programmes
25. OBAT-OBAT GANGGUAN SALURAN PERNAPASAN
25.1 Antiasthmatic and for chronic obstructive pulmonary disease

14.1

14.2

15

17.6 Laxatives
Bisacodyl

Tablets

Lactulose

Syrup 10 mg/15 ml; 50 ml bottle

26. AQUA, LARUTAN ELECTROLIT DAN LARUTAN ASAM BASA DAN NUTRISI
26.1 Oral
26.2 Parenteral
26.3 Miscellaneous
27. VITAMIN, MINERAL DAN NUTRISI

11

15.1

15.2-16

Lubricating jelly for examination and


procedures

Tube with Creme 82 g

13.1 Obat-obat anti jamur


Vital, essential, necessry

V = Vital.
E = Essential,
N = Necessary.
S = Specialist
NP = National Programme

District level CHC; nurses, midwifes, Drs + beds

KODE DAN SINGKATAN

Tablet: 100 mg and 300mg

13. OBAT-OBAT DERMATITIS (topical)

RS Referal

Level 1 Health Post : Bidan / Perawat

DAFTAR OBAT-OBAT ESENSIAL UNTUK FASILITAS PELAYANAN KESEHATAN


PRIMER DAN RS.

Subdistrict Level CHC; midwife + nurse + Dr

12.5 Antithrombotic and fibrinolyitc medicines


Acetylsalicylic acid

Benzoic acid + salicylic acid

Ointment or cream: 6% + 3%, 50 g per tube

Miconazole

Ointment or cream: 2% (nitrate).

Sodium thiosulfate

Solution: 15%.

Selenium sulfide

Detergent based suspension: 2%.

13.2 Obat-obat anti infeksi

1. ANESTESI

Methylrosanilinium chloride (gentian violet)

Aqueous solution: 0.5%, 25g powder in sachet

1.1. Anestesi Umum

Neomycin sulfate + bacitracin

Ointment: 5 mg neomycin sulfate + 250 IU bacitracin zinc/g.

Compressed air

Gas cylinders

Potassium permanganate

Aqueous solution: 1:10 000.

Halothane

Inhalation solution for vaporization, 250 ml

Silver sulfadiazine

Cream: 1%, in 500 g tube

Ketamine

Injection, 50 mg/ml (as hydrochloride) in 10-ml vial

13.3 Anti inflamasi dan anti pruritis


Betamethasone valerate

Ointment or cream: 0.1%

Oxygen

Inhalation (medicinal gas)

Calamine

Lotion and talc

Propofol

Ampoule 200 mg in 20 ml

Hydrocortisone

Ointment or cream: 1%

Thiopental

Powder for injection 1g (sodium salt) in ampoule

13.4 Medicines affecting skin differentiation and proliferation

1.2. Muscle relaxants (peripherally acting) and cholinesterase inhibitors


Atracurium
Neostigmine

Inject 10mg/ml

Injection: 2.5 mg (metilsulfate) in 1 ml ampoule

Injection: 100 mg (chloride) in 2 ml ampoule.

Vecuronium

Powder for injection: 10 mg (bromide) in vial.

1.3. Anetesi Lokal


Spinal 0.5% heavy 5mg/ml (hydrochloride) with 8% glucose 4-ml vial and Bupivacaine 0.5%

Ephedrine

Injection, 30 mg/ml (hydrochloride) in 1-ml ampoule

Lidocaine

Nerve block 15-20mg/ml, 2% with and without adrenaline


Dental Cartridge 2%+1:80,000 adrenaline, And; 2% + epin
10%

Lotion 5%

Coal tar

Solution 5%

Dithranol

Ointment 0,1 - 2%

Fluorouracil

Ointment 5%

Podophyllin paint (Podophyllotoxin)

Solution paint 15%, 5ml

Salicylic acid

Solution 0,5%

Urea

Ointment or cream: 10%.

Suxamethonium

Bupivacaine

Benzoyl benzoate

Lotion: 25%.

Cream: 5%. And Lotion: 1%.

13.5 Scabisid dan Pediduliud


Benzyl benzoate

Lidocaine + epinephrine (adrenaline)

Permethrin

14. DIAGNOSTIC AGENTS


ephrine 1: 100 000 in 5ml vial. And Spray

Dental cartridge 2% + epinephrine 1: 80 000 in 2,2 ml cartridge, And; injection 2% + epinephrine 1:


100 000 in 5ml vial

14.1 Ophthalmic medicines

Fluorescein

Eye drops: 1%

Tropicamide

Eye drops: 0.5%.

14.2 Radiocontrast media


Phenylephrine

Injection, 10mg (as hydrochloride)/ml in 1-ml ampoule

Metaraminol

Injection 10mg/ml

Amidotrizoate

1.4. Preoperative medication and sedation for short-term procedures


Atropine

Injection, 1 mg (sulfate) in 1-ml ampoule OBS ONLY ONE STRENGTH TO BE SUPPLIED, TO


MINIMIZE RISK FOR ERRORS !

Diazepam

Injection, 5 mg/ml in 2-ml ampoule (intravenous or rectal), Tablets 5mg

Promethazine

Oral liquid 5mg.5mL

Injection: 140 420 mg iodine (as sodium or meglumine salt)/ml in


20 ml

Barium sulfate

Aqueous suspension. Powder for 25 kg, preparatioon of suspension, for per oral intake as x-ray
contrast, and for preparation of enema for x-ray contrast

Iohexol (Omnipaque or equivalent)

Injection: 140 350 mg iodine/ml in 5 ml; 10 ml; 20 ml ampoules.

Meglumine iotroxate (Meglumine


Amidotrizoate 66g (gastrografin)

Solution 5-8 g iodine in 100-250 ml. 370 mg iodine/mL

v
Datrizoate Meglumine & Diatrizoate Sodium

Solution 76%

Iopramide (Ultravist 60 or equivalent)

300 mg iodine / ml

Iopramide (Ultravist 76 or equivalent)

370 mg iodine /ml

Ultrasound examination gel

500 ml bottle

10

11. BLOOD PRODUCTS AND PLASMA SUBSTITUTES

2. ANTI NYERI, ANTI PIRETIK, NSAIDs DAN REMATIK

All supply of blood products and plasma fractions must comply with the WHO Requirements for the Collection, Processing and Quality Control of
Blood, Blood Components and Plasma Derivatives (Revised 1992). (WHO Tech. Report Series, No. 840, 1994, Annex 2).

2.1 Non-opioids and non-steroidal anti-inflammatory medicines (NSAIDs)

Dextran 40 (see protocols for Dengue and


paediatrics)

Injection solution,500 ml bag, OBSERVE each infusion bag also to be delivered together with
ampoule of Promitene included, to be injected first before infusion starta to prevent anaphylaxis

Gelatine hydrolysate plasma expander

Infusiion solution 500 ml Polygeline, 3.5%

Human normal immunoglobulin

Intramuscular administration: 16% protein solution.


Intravenous administration: 5%; 10% protein solution.

Tablet, 100mg and 500 mg, And; Suppositories: 50 mg, 150 mg.

Diclofenac

Diclofenac Tablet 25mg,50mg


Injection 25mg/ml in 3ml ampoule
Suppository 12.5mg, 50mg,100mg

Ibuprofen

Tablet, 200mg, 400 mg, and syrup 100 mg/ 5ml

Paracetamol

Tablet scored 500mg and 100mg, Suppository, 100 mg, Oral liquid/Syrup, 125 mg/5ml bottle volume
60 ml,

2.2. Opioid analgesics

12. OBAT-OBAT GANGGUAN JANTUNG


12.1 Antianginal medicines
Acetylsalicylic acid thrombose prophylaxis for
Unstable A

Tablet 100 mg

Atenolol

Tablet: 50 mg; (100 mg).

Glyceryl trinitrate

Tablet (sublingual), 300 microgram, 500 microgram, Injection 600 microgram / 2mL vial

Isosorbide dinitrate
Verapamin

Tablet (sublingual): 5 mg.

Tablet 40mg, 80mg

12.2 Obat-obat anti Aritmia


Amiodarone hydrochloride

Acetylsalicylic acid

Tablet 100mg, 200 mg, Injection 150mg/3mL ampoule

Clonidin (as co-analgesic)

Injection solution 150 microgram per mL in ampoule

Codeine phosphate

Tablet, scored 30 mg (phosphate)

Fentanyl

Injection, 100microgram (as citrate) in 2ml ampoule (50 mcg/ml)

Morphine

Tablet 10 mg. Tablet slow release: 10 mg; 30 mg; 60 mg (morphine sulfate). Oral liquid: 10 mg
(morphine hydrochloride or morphine sulfate) /5 ml. Injection solution, 10 mg in 1-ml ampoule
(sulfate or hydrochloride)

Pethidine (short term opoid, obstetrics)

Injection solution, intramuscular dose of pethidine 100 mg

Tramadol

Tablet or capsule, 50 mg (hydrochloride), And; injection, 50 mg (hydrochloride)/ml in 2-ml ampoule

Allopurinol

Tablet, 100 mg

Diclofenac Sodium

Tablet, 50 mg, And; injection 50 mg, 100 mg

Colchicine

Tablet, 500 mcg

2.3. Medicines for treatment of gout


Atenolol (also antianginal)

Tablet: 50 mg; 100 mg.

Digoxin

Tablet, 62.5 microgram, 125 microgram and 250 microgram; Oral solution, 50 microgram/ml; And;
Injection solution 250 microgram/mL in 2mL ampoule

x
s

v
v

Epinephrine (adrenaline)

Injection, 100 microgram / mL (as hydrochloride) in 10 mL ampoule, 1 mg/mL (as hydrochloride) in 1


mL ampoule.

Lidocaine

Injection, 20 mg (hydrochloride)/ml in 5-mlampoule

Verapamil (also antianginal)

Injection: 2.5 mg (hydrochloride)/ml in 2


Tablet: 40 mg; 80 mg (hydrochloride).

2.4 Disease modifying agents used in rheumatoid disorders (DMARDs)

ml ampoule.

Tablet: 5 mg, 10mg

Atenolol

Tablet: 50 mg; 100 mg.

Enalapril

Tablet: 2.5 mg, 5 mg, 10mg

Hydralazine

Tablet, 25 mg, 50 mg (hydrochloride); powder for injection, 20 mg (hydrochloride) in ampoule

Hydrochlorthiazide.
Metoprolol

Tablet: 100 mg; 150 mg (as phosphate or sulfate).

Azathioprine

Tablet: 50 mg.

Methotrexate

Tablet: 2.5 mg, and 10mg (as sodium salt).

Penicillamine

Capsule or tablet: 250 mg.

Sulfasalazine

Tablet: 500 mg.

12.3 Obat-obat anti Hipertensi


Amlodipine

Chloroquine

3. ANTIALLERGICS DAN OBAT-OBAT ANAPILAKSIS DAN PENANGANAN SHOK

3.1. Corticosteroids

Dexamethasone

Injection, 4 mg/mL dexamethasone phosphate in 1-ml ampoule, And; tablet, 0,5 mg and 5 mg

Tablet 25 mg (scored to be possible to start at 12,5 mg)

Epinephrine / adrenaline

Injection, 1 mg (as hydrochloride or hydrogen tartrate) in 1-ml ampoule

Tablet, 50mg, 100mg

Hydrocortisone

Powder for injection, 100 mg sodium succinate in vial

Methyldopa

Ttablet, 250 mg

v
Prednisolone

Tablet, 5 mg, 25mg, And; Oral liquid: 5mg/ml.

Nifedipine (use with care considering the risk


for stroke with too fast BP reduction !)

Tablets 5 mg and 10 mg

v
Promethazine

Tablet 500 microgram, 1 mg

Tablet, 25 mg (as hydrochloride) and as syrup, And; injection, 25 mg (as hydrochloride)/ml in 2-ml
ampoule. *for premedication and reatment of anaphylactic reactions

Prazosin
Sodium nitroprusside

Powder for infusion: 50 mg in ampoule. OBSERVE that after dilution, N need to be mixed with 5%
glucose for infusion.

3.2. Obat-obat penanganan shok


Dopamine

Injection solution, 40mg/mL in 5 mL10mL, 20mL ampoules

12.4 Medicines used in heart failure


Digoxin

Tablet, 62.5 mcg, 250 mcg; oral solution, 50 mcg/ml; Injection: 250 micrograms/ml in 2
Oral liquid: 50 micrograms/ml.

Enalapril

Tablet: 2.5 mg, 5 mg, 10mg, And Injection, 250 microgram/ml in 2-ml ampoule

Furosemide

Tablet, 40 mg scored; Solution for injection 10 mg/ml in 2-ml ampoule

Hydrochlorothiazide (combined use with


ACEI)

Tablet (scored): 25 mg.

Spironolactone

Tablet 12,5 - 25 mg

Dopamine

Injection: 40 mg/ml (hydrochloride) in 5

ml ampoule.

ml vial.

4.Antidotum.
Charcoal activated

Tablet 125 mg - replaced by powder for oral suspension, bottle, 50g

Potassium citrate, for alkalinization of urine


(Barbiturate poisoning, and for urology
procedures)

Oral liquid, 30%

Atropine

Injection, 1 mg (sulfate) in 1-ml ampoule

8. ANTINEOPLASTIC, IMMUNOSUPPRESSIVE AND PALLIATIVE CARE. These medicines need an additional selection
and procurement process to match the supply with currently used protocols at the National Hospital. Listed drugs only serve as a list of
commonly used preparations. This section need frequent updates through recurrent consultations with the National hospital.
8.1 Immunosuppressive medicines
8.2.1. A. Cytotoxic medicines and antihormones. ONLY FOR NHGV. Supply of these medicines will requires a
Calcium folinate (folinic acid)

Methotrexate
Acetylcysteine

Injection: 200 mg/ml in 10 ml ampoule.

Calcium gluconate

Injection: 100 mg/ml in 10 ml ampoule.

Methotrexate

Deferoxamine

Tablet 15mg
Powder for injection, 50 mg (as sodium salt) in vial
Tablet, 2.5 mg (as sodium salt), and tablet, 10 mg (as sodium salt)

All other chemotherapy to be listed and procured under specialist order from National hospital

8.2.1. B. Hormones and antihormones in antineoplastic care

Powder for injection: 500 mg (mesilate) in vial.

All hormones for management of neoplasia to be listed and procured under specialist order from National hospital
DL-Methionin

x
Tablet: 250 mg.

Methylthioninium chloride (methylene blue)

9. OBAT-OBAT ANTI TREMOR

Injection: 10 mg/ml in 10 ml ampoule.

Naloxone

Injection 400 microgram, 1ml ampoule

Penicillamine

Capsule or tablet: 250 mg..

Sodium calcium edetate

Injection: 200 mg/ml in 5 ml ampoule.

Benztropine mesylate

Tablet, 2mg as mesylate, injection 1mg/ml, in 2 ml ampoule

Levodopa + carbidopa

Tablet: 100 mg + 10 mg; 250 mg + 25 mg.

10. OBAT-OBAT ANTI GANGGUAN DARAH


x

Sodium nitrite

10.1 Antianaemia medicines


Iron / Ferrous salt

Oral liquid: equivalent to 25 mg iron (as sulfate)/ml.


Tablet: equivalent to 60 mg iron.

Iron Ferrous salt + folic acid

Tablet equivalent to 60 mg iron + 400 micrograms folic acid. Tablet equivalent to 200 mg iron + 200
microgram folic acid. Iron syrup (ferrous fumarate 100 mg per 5 mL corresponding to 20 mg/mL
iron)

hydroxocobalamin

Injection: 1 mg in 1 ml ampoule.

Injection: 1000 IU/ml; 5000 IU/ml; 20,000 IU/ml in 1

Injection: 30 mg/ml in 10 ml ampoule.

Sodium thiosulphate

Injection: 250 mg/ml in 50 ml ampoule.

10.2. Obat-obat anti Pembekuan Darah

5. OBAT-OBAT ANTI KEJANG DAN ANTI EPILEPSI


Carbamazepine
Diazepam

Scored tablet, 200 mg and 100mg, Oral liquid 100mg/5mL, Tablet scored 100mg and 200 mg

Injection, 5 mg/ml in 2-ml ampoule (intravenous or rectal), scored tablet, 2mg and 5 mg

Protamine sulphate

Injection: 10 mg/ml in 5 ml ampoule.


Tablet 500 mg, and injection 100mg/ml in 5 ml vial

Injection: 1mg/ml And; 10 mg/ml in 5

Ethosuximide

Capsule: 250 mg. And; Oral liquid: 250 mg/5 ml.

Tranexamic 500mg

Lidocain

Injection 200 mg / ml solution for injection

Vitamin K1 (Phytomenadione)

Magnesium sulphate

Injection, 500 mg/ml in 10-ml ampoule injection, AND; 500 mg/ml in 2-ml ampoule (50% and 25%
Concentration)

Midazolam (only for anaesthesia)

Solution for injection 1 mg/ml ampoule

Phenobarbital

IV injection: 200 mg/ml (phenobarbital sodium) in ampoule 2 ml volume, Oral Solution 15mg/5mL,
and; Tablet 15 mg, 30 mg and 100 mg

Phenytoin

Capsule, 25 mg, 50 mg, 100mg. Injection, 50 mg/mL in 5 mL vial, Oral liquid 25 mg/5mL, Tablet
25mg, 50mg, 100mg. Tablet chewable 50 mg

Valproic acid

Oral liquid: 200 mg/5 ml, Tablet crushable 100mg, Tablet enteric coated, 200mg, 500 mg

Heparin sodium

ml ampoule.

ml ampoule. Tablet 10mg

6. OBAT-OBAT ANTI INFEKSI


6.1 Anthelminthics
6.1.1 Intestinal anthelminthics
Albendazole

Chewable scored tablet, 400 mg

Niclosamide

Tablet chewable 500 mg

Praziquantel

Tablet 150 mg, 600mg

Pyrantel

Oral liquid, 50mg/mL as ebonate, tablet, chewable 250mg

6.1.2 Antifilarials, antischistozomal anti trematode


Schistozoma Jap is endemic elsewhere in the near region, but no data available in accessible healthcare statistics for TL. Consider possible needs
for medicine under this heading.
Diethylcarbamazine

Tablet, 100 mg (dihydrogen citrate)

6.5 Obat-obat Anti Protozoa

6.2. For ectoparasites

6.5.1 Antiamoebic and antigiardiasis medicines

Ivermectin

Diloxanide furoate

Tablet, 500 mg (furoate)

Metronidazole

Injection: 500
mg in 100 ml vial.
Oral liquid: 200 mg (as benzoate)/5 ml.
Tablet: 200 500 mg.

6.2.1 Obat-obat Beta Lactamase


Scored tablet, 250mg, 500mg, And; Syrup (125mg/5ml) (Powder for preparation of oral
suspension), 100 ml bottle

Amoxicillin + clavulanic acid

Tablet 625 mg Tablet (scored) containing 500 mg Amoxicillin plus 125 mg Clavulanic Acid. And;
Syrup containing 125 mg Amoxicillin + 31,25 mg Clavulanic acid per 5 mL.And Syrup containing 250
mg Amoxicillin plus 62,5 mg Clavulanic acid per 5 mL

Ampicillin

Powder for injection, 500mg, 1 g (as sodium salt) in vial

Benzathine benzylpenicillin

Powder for injection, 600 mg (= 1 million IU) vial, And; powder for injection, 1.8g vial (equivalent to
1.44g benzylpenicillin, 2.4 million IU) in 5-ml vial

Artesunate

Injection 60 mg powder, packed together with a separate ampoule of 5% sodium bicarbonate


solution, Tablet 50mg, 100mg, suppository 400mg

Benzylpenicillin (Penicillin G)

Powder for injection; Vial with 600 mg (1 million Units). Vial with 3 g (= 5 million IU).

Cefaclor

Capsule 250mg, 500mg. Oral liquid/syrup 125mg, 250mg/5mL

Cephazolin (Cefazolin), Gyn surg prophylax


Cefixime (now recommended for Gonorrhoea,

instead of previous Ciprofloxacin)

Cloxacillin

Powder for injection: 1 g (as sodium salt) in vial.

Capsule: 400 mg.

(OBS, Only Gonorrhoea according to WHO's updated STI recommendations)

Scored tablets size 250 mg and 500 mg. Powder for injection in vial with 500 mg or 250 mg. Powder
for preparation of oral solution, 125 mg/5mL

Flucloxacillin (Parenteral Fluclox. has lower risk for Injection, 500mg, 1g vial

Chloroquine

Oral liquid: 50 mg (as phosphate or sulfate)/5 ml.


Tablet: 100 mg; 150 mg (as phosphate or sulfate).
* For use only for the treatment of P.vivax infection. Tablets 250 mg and 150 mg,

thrombophlebitis than cloxacillin)

6.5.2.1 For curative treatment


Tablet combined 20mg Artemether/120mg Lumefantrine (Coartem) in blisters; Yellow, Blue, Orange
and Green; Artemether + Lumifantrine (>35 kg) 20mg+ 120mg
Artemether + Lumifantrine ( 25 -35 kg) 20 mg +120mg
Artemether + Lumifantrine (15 - 25 kg) 20mg+120mg
Artemether + Lumifantrine (5-15Kg) 20 mg + 120mg

Amoxicillin

6.5.2 Obat-obat Anti Malaria (Pendistribusian menurut program nasional)

Artemether combined with Lumefantrine


(Coartem)

Tablet, scored 3mg, 6mg

6.2 Antibakteri

Phenoxymethylpenicillin

Scored tablet, 250mg, powder for oral liquid 250 mg/5mL

Procaine benzylpenicillin

Powder for injection 3 g (3 million IU) in ampoule, and 1g (1 millioun IU) in ampoule or vial

Second line beta lactam antibiotics

Doxycycline

Clindamycin

tablet 100 mg capsule or tablet

tablet 300 mg (see also parenteral injection 150 mg, already listed under antibacterials. Parenteral
gives less risk for enterocolitis)

Artemotil (syn Arteether)

Primaquine

Quinine sulphate

Amodiaquine

Oily injection: 80 mg/ml in 1 ml ampoule. Inj 40 mg/ml pediatric dose


For use in the management of severe malaria.

Parenteral solution for intramuscular injection 150mg/2ml (I.M. only)

Tablet: 7.5 mg; 15 mg (as diphosphate)


* Only for use to achieve radical cure of P.vivax and P.ovale infections, given for 14 days.

Injection: 150 mg/mL and 300 mg/mL quinine hydrochloride in 2 ml ampoules.


Tablet: 300 mg (quinine sulfate) or 300 mg (quinine bisulfate).
* For use only in the management of severe malaria, and should be used in combination with
doxycycline.

Tablet 200mg

Capsule or tablet, 100 mg ( hydrochloride)

Tablet, 1 mg (tartrate) + 100 mg

Paracetamol

Tablet, 500 mg

7.2 Untuk Profilaksis


Propranolol

Ceftriaxone

Powder for injection: 1 g in vial.

Chloramphenicol

Scored tablet 250 mg, oily suspension for injection 0,5 g as sodium succinate/ml in 2ml ampoule,
oral liquid 150 mg as palmitate/5mL, powder for injection 1g as sodium succinate in vial.

Ciprofloxacin

Tablet 100mg, 250 mg and 500 mg

Clindamycin

Capsule: 150 mg. (See also under Malaria protocol drugs)


Injection: 150 mg (as phosphate)/ml.

Cotrimoxazol (sulfamethoxazole +
trimethoprim)

Injection: 80 mg + 16 mg/ml in 5 ml and 10 ml ampoules.


Oral liquid: 200 mg + 40 mg/5 ml.
Pediatric tablet: 100 mg SMX + 20 mg TMP; Adult tablet; 400 mg SMX + 80 mg TMP. And; powder
for oral suspension for children; 40 mg TMP + 200 mg SMX per 5 mL

Doxycycline

Tablets 100 mg (also listed as malaria prophylaxis)

Erythromycin

Capsule or tablet: 250 mg (as stearate or ethyl succinate).


Powder for injection: 500 mg (as lactobionate) in vial.
Powder for oral liquid: 125 mg/ 5 ml (as stearate or ethyl succinate). For eyes, see separate section

Gentamicin

Injection solution 10 mg/mL in 2 mL vial; 40 mg/mL in 2 mL vial and (Gentamicin as sulfate).


Injection solution to be added to 500 mL 5% Dextrose as infusion solution.

Metronidazole

Injection: 500 mg in 100 ml vial.


Oral liquid: 200 mg (as
benzoate)/5 ml.
Suppository: 500 mg; 1 g. Vagitorties 500mg
Tablet, scored: 200 500 mg.

Nalidixic acid

Tablet, scored 500mg

Nitrofurantoin

7. OBAT-OBAT ANTI MIGRAN

Ergotamine +caffeine

7.1 Untuk Pengobatan Akut


Tablet, 300 mg

6.5.3 Antipneumocystosis anti toxoplasmosis medicines

Acetylsalicylic acid

Tablets; 250 or 500 mg as cefuroxime axetil. Powder for injection, 750 mg. Powder for syrup, 125
mg/5 ml.

6.5.2.2 Untuk Profilaksisi Malaria


Doxycycline

Vial of 500 mg or vial 1g or 2 g powder for injection

Cefuroxim powder for injection, and Cefuroxim


as axetil in tablets

6.2.2 Antibiotik Lain

Artemether

Cefotaxime

Tablet: 100 mg.

Spectinomycin

Powder for injection: 2 g (as hydrochloride)


in vial.

Sulfadiazine

Injection: 250 mg (sodium salt) in 4


Tablet: 500 mg.

Tetracycline

Tablet scored 500mg, Eye ointment 1%

Trimethoprim

Tablet: 100 mg; 200 mg.

ml ampoule.

np np

np

np

np np

np

np

6.2.3 Obat-obat Antilepna


Tablet: 20 mg; 40 mg (hydrochloride).

Clofazimine
Dapsone

Capsule, 50 mg and 100mg


Tablet: 25 mg; 50 mg; 100 mg.

7
4

Prednisolone

np np

np

np

Capsule or tablet, 150 mg and 300 mg

np np

np

np

Paucibacillary Adult L: 6 Blister Packs

Tablets/Capsules in Blisters: Rifampicin 300 mg, Dapsone 100 mg,

np np

np

np

Multibacilary Adult L: 12 Blister Packs

Tabets/Capsules in blisters: Rifampicin 300mg, Clofazimine 100 mg, and Dapsone 100 mg

np np

np

np

Rifampicin

Paucibacillary Child L: 6 Blister Packs


Multibacillary Child L: 12 Blister Packs

Tablet, 5 mg, 25mg

Tablets/Capsules in Blisters: Rifampicin 300 mg, and Dapsone 50 mg


Tablets/Capsules in Blisters: Rifampicin (300 mg + 150 mg), Clofazimine 50mg, and Dapsone 50
mg.

np np
np np

np
np

np
np

6.3 Antifungal medicines


Clotrimazole

Vaginal tablet 100mg, 500 mg or pessary plus applicator, eye drops 1%, nose and ear drops 1%,
Cream 1%,

Fluconazole

Griseofulvin

6.2.4.1. Anti tuberculosis fixed drug combinations


Tablet combination in blister pack; Rifampicin (150mg), Isoniazide (75mg), Ethambutol (275mg),
Pyrazinamide (400 mg)

2-Drug fixed combination, for Continuation


phase treatment of patients of Cathegory I.

Tablet combination in blister pack: Isoniazide (150mg), Ethambutol (400mg)

2-Drug fixed combination, for intensive phase


treatment, paediatric patients

Tablet combination in blister pack; Rifampicin (150 mg), Isoniazide (75mg)

Capsule or Tablet: 50 mg and 200 mg. Injection: 2 mg/ml in vial. Oral liquid: 50 mg/5 ml.

Tablet scored 500 mg, Capsule or tablet 125 mg; 250 mg.

Ketoconazole

Tablet, 200mg, Oral liquid 100mg/5mL, Creak 2%

Miconazol

Crme 2% 20g

Nystatin

Pessary: 100 000 IU. Tablet: 100 000 IU; and 500 000 IU. Oral suspension 100,000 Units / mL

Potassium iodide

Saturated solution.

6.4 Antivirals
np np

np np

np

np

np

np

6.4.1 Antiherpes medicines

Aciclovir (Acyclovir)

Tablet, 200mg

Aciclovir (Acyclovir)

Powder for injection: 250 mg in vial.

6.4.2 Antiretrovirals
6.4.2.1 Nucleoside reverse transcriptase inhibitors (distributed according to national program np)

2-Drug fixed combination, for continuation


phase treatment for Paediatric patients, and
for patients Cathegory II.

Tablet combination in blister pack; Rifampicin (150mg), Isoniazide (150mg)

Ethambutol, for the continuation phase


treatment, for patients Cathegry II

Tablet 400mg

Streptomycin Sulphate (for intensive phase


addition, for patient Cathegory II

powder for injection 1gr

Pyrazinamide (for prevention of neurological


adverse reactions of isoniazide)

6.2.4. (TBC) Distribusi Menurut Program Nasional


4-drug fixed combination, for Intensive-phase
treatment, for patient Cathegory I & II

Tablet 400 mg

np np

np np

np np

np np

np np

np

np

np

np

np

np

np

np

np

np

Isoniazide (single substance, for prevention


treatment for child exposed to TB positive
patient.

Tablet, scored 100 mg

np np

np

np

Water for injection

Vial of 5 ml each

Abacavir (ABC)

Tablet, 300mg (as sulfate), oral solution, 100mg (as sulfate)/5ml

np np

np

np

Didanosine (ddI)

Chewable tablet, 25mg, 100mg

np np

np

np

Didanosine (ddI)

Powder for per oral solution, 4 g

np np

np

np

Lamivudine (3TC)

Tablet, 150mg, Oral solution 50 mg/5ml

np np

np

np

Lamivudine (3TC)

Oral liquid 10 mg/ml (50mg/5mL)

np np

np

np

Nevirapine(NVP)

Tablets 200mg, oral suspension 50 mg / 5mL

np np

np

np

Stavudine (d4T) / Estavudin

Capsule 30mg, 40mg,

np np

np

np

Tenofovir (TDF)

Capsule 300mg

np np

np

np

Zidovudine (ZDV or AZT)

Tablet, 300mg , oral solution syrup, 50mg/5ml

np np

np

np

Zidovudine

Solution for i.v. Infusion 10 mg/ml in 20 mL vial

np np

np

np

Zidovudine

Oral solution 50 mg / 5 ml

np np

np

np

np np

np

np

6.4.2.2 Non-nucleoside reverse transcriptase inhibitor. (distributed according to national program np)
Efavirenz (EFV or EFZ)

Capsule, 50mg, 200mg, 600mg

6.4.2.3 Protease inhibitors (distributed according to national program np)


Indinavir (IDV)

Tablet: 400 mg (as sulfate).

np np

np

np

Lopinavir + ritonavir (LPV/r)

Capsule: 133.3 mg + 33.3 mg. and Oral liquid: 400 mg + 100 mg/5 ml.

np np

np

np

Nelfinavir (NFV)

Oral powder: 50 mg/g. and Tablet: 250 mg

np np

np

np

Ritonavir

Oral liquid: 400 mg/5 ml. and Oral solid dosage form: 100 mg.

np np

np

np

Saquinavir (SQV)

Capsule: 200 mg.

np np

np

np

6.4.2.3.1. Supplementary list with available fixed combinations (distributed according to national program np)
AZT+3TC+NVP

According to the National program

np np

np

np

d4T+3TC+NVP

According to the National program

np np

np

np

AZT+3TC+IDV+RTV

According to the National program

np np

np

np

Efavirenz + emtricitabine* + tenofovir

Tablet: 600 mg + 200 mg + 300 mg.

np np

np

np

Emtricitabine* + tenofovir

Tablet: 200 mg + 300 mg.

np np

np

np

Stavudine + lamivudine + nevirapine

Tablet: 30 mg + 150 mg + 200 mg.

np np

np

np

Zidovudine + lamivudine

Tablet: 300 mg + 150 mg.

np np

np

np

Zidovudine + lamivudine + nevirapine

Tablet: 300 mg + 150 mg + 200 mg.

np np

np

np

6.4.2.3.2 Fixed combinations to prevent mother-to-child transmission(distributed according to national program np)

Ante- intra and postpartum preparation to


prevent MCT

AZT+3TC+NVP Twice daily. According to National Program

np np

np

np

Infant preparation to prevent MCT

AZT x 7 days. According to National Program

np np

np

np

ARV prophylaxis for infants born to HIV+


women not received ante- or intrapartum
therapy

Sd-NVP for use immediately after birth + AZT X 4 weeks. According to National Program

np np

np

np

You might also like