Chemicals Evaluated For Carcinogenic Potencial Office of Pesticides Progras US-EPA

October 2, 2014
Chemicals Evaluated for Carcinogenic Potential

Office of Pesticide Programs
U.S. Environmental Protection Agency
BACKGROUND
What is this list?
The following list provides an overview of pesticide chemicals evaluated for carcinogenic
potential by EPAs Pesticide Program through October 2012. The evaluation of many of these
chemicals is an ongoing process. Therefore, the information in this list may be subject to
change as new and/or additional data are submitted to EPA. This list will be updated annually.
How should the information provided in this list be used?
Although this list is available to the public, note that the list represents only the potential
carcinogenicity hazard for the chemical with no consideration of exposure information. This list
is not intended to be used independent of the full risk assessment for the chemical. When
EPA completes a risk assessment on a pesticide, a variety of toxicity information, including
potential for noncancer effects (e.g., neurotoxicity, developmental and reproductive toxicity,
immunotoxicity, etc) and carcinogenicity, are considered in determining whether to register a
pesticide and what requirements for use of the pesticide need to be in place to protect human
health. The simple fact of being listed here does not imply that the pesticide poses a
significant cancer hazard to the public from use
What does the report date mean?
The date included in the list for each chemical is the date of the most recent review of potential
carcinogenicity hazard for that chemical. This date provides a key as to which set of cancer
guidelines were used in the review. Note that the classification of potential carcinogenicity
generally is not reevaluated unless new data are submitted.
How does EPA review pesticides for potential carcinogenicity?
In evaluating and describing the potential carcinogenicity of a pesticide, EPAs Pesticide
Program follows the Agencys Guidelines for Carcinogen Risk Assessment (see
http://epa.gov/cancerguidelines/ for more information). The Health Effects Division of the
Pesticide Program performs an independent review of all the available evidence to determine
the carcinogenic potential of pesticides.
The results of the independent review are peer-reviewed by the Cancer Assessment Review
Committee. This committee recommends a descriptor (e.g., likely to be carcinogenic to
humans, not likely to be carcinogenic to humans, suggestive evidence of carcinogenic
potential) to convey the cancer hazard potential of the compound. This descriptor is also
referred to as the cancer classification. The evidence for the human cancer potential and the
extent to which a person might be exposed (how much time and to what quantity of the
pesticide) will determine how the Agency regulates the pesticide. In some cases, EPA may
request a review by the FIFRA Scientific Advisory Panel.
What does EPA consider in its review of cancer risk?

In determining the cancer-causing potential of a chemical, EPA considers the full range of
available evidence. This information includes
laboratory animal findings,

metabolism studies,
structural relationships with other carcinogens, and
if available, mode of carcinogenic action information and epidemiologic findings in
humans.
All of the information is considered in a weight-of-the-evidence approach. In this weight-ofevidence evaluation, EPA undertakes a critical analysis of each available study to determine
its quality and reliability. Then the entire body of evidence is integrated and examined for
consistency (repeatability of findings in studies), cohesiveness (a logical pattern of responses),
and for biological plausibility (i.e., are the observed findings consistent with current
understanding of carcinogenic processes). How the Agency determines the cancer potential of
a compound can be found at: http://epa.gov/cancerguidelines/
Most of the cancer determinations for pesticides are largely based on laboratory animal studies
because, under its statutory authority, EPA requires registrants to submit an extensive range of
laboratory studies on pesticides including long-term rodent cancer studies
(http://www.epa.gov/pesticides/regulating/data_requirements.htm). The findings in laboratory
animals are generally assumed to be relevant to humans unless there is evidence to the
contrary. When human information is available, EPA would consider that information (for
example see http://www.epa.gov/pesticides/health/ag-health.html.)
When does EPA review pesticides for potential carcinogenicity?
EPA reviews studies submitted when a pesticide is proposed for registration. Studies are
required in two species (mice and rats) and two sexes (males and females), as well as a
battery of mutagenicity assays. These studies are required for all pesticides used on food and
some non-food pesticides that could lead to long-term exposures in humans. In future reviews
of the pesticide, the cancer classification may be reevaluated if new studies have been
submitted.
All existing pesticide tolerances that were in place as of August 1996 were re-assessed for
their human health and environmental risks by August 2006 as required by the Food Quality
Protection Act of 1996. However, if there was no new information on carcinogenicity, the
compound was not re-evaluated simply to determine how it would be described under the 2005
cancer guidelines.
How have the Agencys cancer assessment guidelines changed?
There have been a number of different documents issued by the Agency for cancer evaluation.
In 1976, EPA issued its first set of principles and interim procedures to guide evaluation of
human cancer potential.
In 1986, EPA issued guidance, which included a letter system (A-E) for designating degree of
carcinogenic potential.
o In the 1986 guidelines, hazard identification and the weight-of evidence process focused
on tumor findings.
See http://epa.gov/cancerguidelines/guidelines-carcinogen-risk-assessment-1986.htm
for a detailed description of this classification system.
In 1996, EPA released Proposed Guidelines for Carcinogen Risk Assessment, which used a
weight of evidence narrative and standardized descriptors to replace the 1986 alphanumeric
classification to classify carcinogenic potential.
o In the 1996 proposal, emphasis was placed on available mode of carcinogenic action
information and discussing characterization of hazard, dose-response, and exposure
assessments.
o The hazard and weight of evidence process embraced an analysis of all relevant
biological information and emphasized understanding the agent's mode of action in
producing tumors to reduce the uncertainty in describing the likelihood of harm.
o See 1996 -http://www.epa.gov/raf/publications/pdfs/propcra_1996.pdf
In 1999, EPA issued a revised version of its 1996 proposal that responded to public and peer
review comments, which included:
o a framework approach to evaluate the mode of action in the assessment of potential
carcinogenesis.
o See-http://epa.gov/raf/publications/pdfs/CANCER_GLS.PDF
In March, 2005, EPA released its final Guidelines for Carcinogen Risk Assessment (EPA/630/P03/001B). These guidelines represent the culmination of a long development process, replacing
EPAs original cancer risk assessment guidelines (1986) and its interim final guidelines (1999).
Key changes included:
o Five weight of evidence descriptors chosen for use in narratives (Carcinogenic to
Humans, Likely to Be Carcinogenic to Humans, Suggestive Evidence of Carcinogenic
Potential, Inadequate Information to Assess Carcinogenic Potential, and Not Likely to
Be Carcinogenic to Humans.)
o Emphasis on analysis of data will precede use of defaults
o Improved guidance on modeling and expanded discussions of sensitive subpopulations
including children (supplemental guidance)
o See http://www.epa.gov/raf/publications/pdfs/CANCER_GUIDELINES_FINAL_3-2505.PDF
o
Why are there several different cancer classifications in the list?

As discussed above, EPAs guidelines for evaluating the potential carcinogenicity of chemicals
have been updated over the years to reflect increase transparency in describing the cancer
potential of a compound and to reflect the understanding of ways chemicals may cause
cancer.
Not all pesticides have been evaluated under EPAs 2005 Cancer Guidelines. Agency policy
states that for risk assessments that were completed before issuance of the 2005 Guidelines,
the need for a re-assessment should be determined on a case-by-case basis by the program
and that the existing assessment should continue to be considered scientifically sound based
on the guidance used when the assessment was completed
(http://www.epa.gov/raf/publications/pdfs/2005_cancer_guidelines_mem.pdf)
How can I find the basis of EPAs decision regarding the carcinogenicity of a pesticide?
The Reregistration Eligibility Decision for each pesticide contains a discussion of the available
data and information used in the human health and environmental risk assessments, which
includes a description of the evidence used to determine the cancer potential of the chemical.
Also, the Cancer Assessment Review Committee report is available by requesting it through
the Freedom of Information Act (FOIA) (link to http://www.epa.gov/pesticides/foia/).
Annual Cancer Report October 2, 2014

CHEMICAL
1,3Dibromo5,5
dimethylhydantoin
CAS NO.*
PC
CANCER
CODE** CLASSIFICATION***
REPORT
DATE****
1,3dichloro5methylhydantoin 89415872
NotLikelyToBeCarcinogenic
006317 ToHumans
8/28/2000
NotLikelytoBeCarcinogenic
128826 toHumans
8/28/2000
2,4DBA
94826
030801 toHumans
6/13/2003
94757
GroupDNotClassifiableasto
1/29/1997
030001 HumanCarcinogenicity
2,4D+Salts&Esters
2,4DCholine
2Benzyl4chlorophenol
4aminopyridine
77485
GroupDNotClassifiableAs
1048373723 051505 ToHumanCarcinogenicity
GroupCPossibleHuman
120321
062201 Carcinogen
504245
Acephate
30560191
Acequinocyl
57960197
Acetamide
63114772
Acetamiprid
135410207
Acetochlor
34256821
AcibenzolarSmethyl
135158542
Acifluorfensodium
62476599
069201 ToHumanCarcinogenicity
10/27/2011
9/5/1995
8/6/2007
GroupCPossibleHuman
103301 Carcinogen
5/8/1985
11/13/2003
006329 toHumans
GroupCPossibleHuman
111101 Carcinogen
5/29/1990
099050 toHumans
SuggestiveEvidenceof
121601 CarcinogenicPotential
061402 toHumans
LikelytobeCarcinogenicto
HumansatHighDosesNot
114402 HumansatLowDoses
12/11/2001
1/3/2007
12/9/1999
7/9/2003
Page 1
For information about future review of these pesticides, see the Registration Review schedule/status at
http://www2.epa.gov/pesticide-reevaluation

CHEMICAL
CAS NO.*
Acrinathrin
101007061
ADBAC
68424851
Alachlor
15972608
Aldicarb
116063
AlphaCypermethrin
67375308
Ametryn
834128
Amicarbazone
129909906
858956088,
858956351,
858954833,
124423843,
1759531
288008 ToHumans
11/9/2011
150114719 005100 ToHumans
7/12/2005
SuggestiveEvidenceOf
348635870 016330 CarcinogenicPotential
12/2/2010
33089611
7/18/2006
Aminocyclopyrachlor
Aminopyralid
Amisulbrom
Amitraz
Amitrole
61825
Anthraquinone
84651
PC
CANCER
REPORT
DATE****
7/15/1996
069105 toHumans
12/8/1999
Humans(HighDoses);Not
6/27/1997
090501 Humans(LowDoses)
GroupEEvidenceofNon
098301 carcinogenicityforHumans
7/17/2002
GroupCPossibleHuman
209600 Carcinogen
09/11/12
DataAreInadequateforan
AssessmentofHuman
9/17/2004
114004 ToHumans
8/10/2005
ToHumansAtDosesThatDo
NotAlterRatThyroid
5/11/2006
004401 HormoneHomeostasis
LikelyToBeCarcinogenicTo
122701 Humans
10/31/12
Page 2

CHEMICAL
CAS NO.*
PC
CANCER
Aquashade
2650182
110301
Asulam
3337711
106901
Atrazine
Avermectin(seeEmamectin
Benzoate)
1912249
080803
65195553
122804
Azafenidin
68049832
119016
Azinphosmethyl
86500
058001
Azoxystrobin
131860338
128810
Bendiocarb
22781233
105201
Benfluralin
1861401
084301
Benomyl
17804352
099101
Bensulide
741582
009801
Bentazon
25057890
275200
Benthiavalicarbisopropyl
177406687
098379
BenzylBenzoate
120514
009501
BetaCyfluthrin
68359375
118831
Bifenazate
149877418
000586
Bifenthrin
82657043
128825
ToHumans
GroupCPossibleHuman
Carcinogen
NotLikelytobeCarcinogenic
toHumans
GroupEEvidenceofNon
carcinogenicityforhumans
AssessmentofHuman
CarcinogenicPotential
toHumans
toHumans
GroupEEvidenceofNon
carcinogenicityforHumans
Carcinogenicity,butNot
SufficienttoAssessHuman
GroupCPossibleHuman
Carcinogen
toHumans
GroupEEvidenceofNon
Humans
ToHumans
ToHumans
toHumans
GroupCPossibleHuman
Carcinogen
REPORT
DATE****
9/27/2005
12/6/2001
12/13/2000
6/27/1996
10/18/1999
4/20/1998
1/14/1997
12/16/1997
12/27/2001
9/21/2000
6/10/1999
1/14/1992
10/18/2005
6/28/2007
1/27/2010
8/28/2001
2/19/2003
Page 3

CHEMICAL
CAS NO.*
Bioallethrin
584792
BispyrabacSodium
125401925
PC
CANCER
REPORT
DATE****
12/02/2003
078906 toHumans
8/2/2001
Bitertanol
55179312
117801
Borax
1303964
011102
Boricacid
10043353
011001
Boron
7440428
128945
Boscalid
188425856
128008
Bromacil
314409
012301
Bromoxynil
1689845
035301
Bromuconazole
116255482
120503
Bronopol
52517
216400
Buprofezin
69327760
275100
Butachlor
23184669
112301
Butafenacil
134605644
122004
ToHumans
GroupEEvidenceofNon
GroupEEvidenceofNon
GroupEEvidenceofNon
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
GroupEEvidenceofNon
GroupEEvidenceofNon
Humans
toHumans
11/30/2005
11/24/1993
11/24/1993
11/24/1993
11/14/2002
1/13/1993
03/12/1997
4/24/1995
6/12/1995
3/15/2000
2/24/1999
7/11/2003
Page 4

CHEMICAL
CAS NO.*
PC
CANCER
Butylate
2008415
041405
Cacodylicacid
75605
012501
Cadusafos
95465999
128864
Captafol
2939802
081701
GroupEEvidenceofNon
GroupBProbableHuman
Carcinogen
GroupEEvidenceofNon
GroupBProbableHuman
Carcinogen
Likelyatprolonged,highlevel
exposures,butnotlikelyat
doselevelsthatdonotcause
cytotoxicityandregenerative
cellhyperplasia
Humans
GroupCPossibleHuman
Carcinogen
toHumans
toHumans
toHumans
ToHumans
Captan
133062
081301
Carbaryl
63252
056801
Carbendazim(MBC)
10605217
128872
Carbofuran
1563662
090601
Carboxin
5234684
090201
Carfentrazoneethyl
128639021
128712
Chlorantraniliprole
500008457
090100
Chlordimeform
6164983
GroupBProbableHuman
059701 Carcinogen
Chlorethoxyfos
54593838
Chlorfenapyr
122453730
REPORT
DATE****
11/25/1992
12/14/1999
5/28/1992
5/19/1987
9/22/2004
2/12/2002
4/7/1989
6/17/1997
6/5/2003
5/16/2001
3/4/2009
12/20/1985
3/9/1995
3/18/2003
Page 5

CHEMICAL
CAS NO.*
PC
CANCER
ToHumans
ToHumans
ToHumans
GroupBProbableHuman
Carcinogen
AssessmentofHuman
ToHumans
Humans
GroupEEvidenceofNon
GroupEEvidenceofNon
toHumans
GroupEEvidenceofNon
GroupCPossibleHuman
Carcinogen
ToHumans
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
REPORT
DATE****
ChlorflurenolMethylEster
2536314
098801
Chlorimuronethyl
90982324
128901
Chlormequatchloride
999815
018101
Chloroaniline,p
106478
017203
Chloroneb
2675776
027301
Chloropicrin
76062
081501
Chlorothalonil
1897456
081901
Chlorpropham
101213
018301
Chlorpyrifos
2921882
059101
Chlorpyrifosmethyl
5598130
059102
Chlorsulfuron
64902723
118601
Chlorthaldimethyl(DCPA)
1861321
078701
Clethodim
99129212
121011
Clodinafoppropargyl
105512069
125203
Clofencet(MON21200)
82697710
128726
Clofentezine
74115245
125501
81777891
125401 toHumans
1/31/2001
Clomazone
7/10/2006
2/5/2009
6/12/2007
4/27/1995
12/18/2003
6/30/2010
10/20/1997
10/11/1994
11/23/1993
5/17/1999
7/17/2002
2/10/1995
9/28/2007
2/8/2006
7/23/1996
4/3/1990
Page 6

CHEMICAL
CAS NO.*
PC
CANCER
Clopyralid
1702176
117403
Cloquintocetmexyl
99607702
700099
Cloransulammethyl
147150354
129116
Clothianidin
210880925
044309
CMNP(Pyrazachlor)
6814580
CocamideDiethanolamine
68603429
toHumans
toHumans
GroupEEvidenceofNon
toHumans
207100 Humans
224600 Humans
REPORT
DATE****
12/20/1999
8/31/1999
9/30/1997
1/6/2003
09/20/2011
10/17/2001
CopperCompounds
20427592
Coumaphos
56724
6/13/2006
036501 toHumans
6/25/1999
Cresol,pChlorom
59507
11/28/1995
Cryolite
15096523
075101
Cumyluron
99485764
027902
Cyanazine
21725462
100101
Cyantraniliprole
736994631
090098
Cyazofamid
120116883
085651
Cyclanilide
113136779
026201
HumanCarcinogenicity
12/22/1995
6/11/2008
GroupCPossibleHuman
Carcinogen
7/30/1991
ToHumans
03/07/13
ToHumans
6/3/2009
toHumans
4/9/1997
Page 7

CHEMICAL
CAS NO.*
Cycloate
1134232
Cyflufenamid
180409603
Cyflumetofen
400882077
Cyfluthrin
68359375
Cyhalofopbutyl
122008859
PC
CANCER
REPORT
DATE****
041301 toHumans
9/25/2003
555550 Humans
128831 toHumans
082583 ToHumans
Cyhalothrin
68085858
128867
Cyhexatin
13121705
101601
Cymoxanil
57966957
129106
Cypermethrin
52315078
109702
Cyproconazole
94361065
128993
Cyprodinil
121552612
288202
Cyprosulfamide
221667318
877400
Cyromazine
66215278
121301
Daminozide
1596845
035101
Dantochlor(BCDMH)
118525
028501
6/22/2010
12/30/2013
5/21/2002
12/20/2007
8/25/1993
AssessmentofHuman
4/7/2005
toHumans
1/2/2003
GroupCPossibleHuman
Carcinogen
9/27/1988
ToHumansatdosesthatdo
notcauseamitogenic
responseintheliver
toHumans
ToHumans
GroupEEvidenceofNon
GroupBProbableHuman
Carcinogen
toHumans
12/4/2007
1/14/1998
2/29/2008
1/6/1995
7/26/1991
8/14/2000
Page 8

CHEMICAL
CAS NO.*
Dazomet
533744
DEET
134623
Deltamethrin
52918635
Desmedipham
13684565
Diazinon
333415
Dicamba
1918009
Dichlobenil
1194656
Dichlormid
37764253
Dichlorobenzamide,2,6
2008584
Dichlorvos
62737
Diclofopmethyl
51338273
Dicloran
99309
Diclosulam
145701219
Dicofol
115322
PC
CANCER
REPORT
DATE****
12/7/1993
1/4/1996
097805 toHumans
9/9/2003
GroupEEvidenceofNon
104801 carcinogenicityforhumans
11/20/1995
057801 toHumans
6/17/1997
7/29/1996
GroupCPossibleHuman
027401 Carcinogen
7/18/1995
900497 ToHumans
11/15/2005
11/28/1995
3/1/2000
110902 Humans
5/24/2000
09/05/2006
129122 toHumans
11/9/1999
GroupCPossibleHuman
010501 Carcinogen
6/24/1992
Page 9

CHEMICAL
CAS NO.*
PC
CANCER
Dicrotophos
Didecyldimethylammonium
chloride(DDAC)
141662
035201
7173515
069149
Difenoconazole
119446683
128847
Difenzoquatmethylsulfate
43222486
106401
Diflubenzuron
35367385
108201
DiflufenzopyrSodiium
109293983
005107
Dimethenamid
87674688
129051
Dimethipin
55290647
118901
Dimethoate
60515
035001
Dimethomorph
110488705
268800
Dimethoxane
828002
001001
Dimethylether
115106
900382
Dimethylhydantoin
16079882
006315
Dinocap
39300453
036001
Dinoseb
88857
037505
Dinotefuran
165252700
044312
Diphenylamine
122394
038501
GroupEEvidenceofNon
GroupCPossibleHuman
Carcinogen
GroupEEvidenceofNon
GroupEEvidenceofNon
toHumans
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
toHumans
REPORT
DATE****
10/18/1999
4/11/2000
7/27/1994
5/24/1994
4/27/1995
10/6/1998
9/15/1995
1/5/1990
3/26/2002
5/13/1998
12/21/2000
1/12/1994
toHumans
8/28/2000
GroupEEvidenceofNon
6/22/1994
GroupCPossibleHuman
Carcinogen
6/19/1986
toHumans
3/5/2004
toHumans
4/1/1997
Page 10

CHEMICAL
CAS NO.*
PC
CANCER
Diquatdibromide
85007
032201
Disodiummethanearsonate
144218
013802
Disulfoton
298044
032501
Dithianon
3347226
099201
Dithiopyr(MON7200)
Diuron
97886458
330541
128994
035505
Dodine
2439103
044301
Ecolyst
EmamectinBenzoate(Deoxy
Avermectin)
137512744
122806
Endosulfan
115297
079401
Endothall
069089
GroupEEvidenceofNon
toHumans
GroupEEvidenceofNon
GroupEEvidenceofNon
Known/Likely
ToHumans
toHumans
toHumans
toHumans
ToHumans
Humans
GroupEEvidenceofNon
GroupCPossibleHuman
Carcinogen
REPORT
DATE****
5/12/1994
7/26/2000
4/21/1997
2/23/2006
5/29/1997
5/8/1997
1/24/2008
10/19/1999
3/19/1998
1/31/2000
Epoxiconazole
145733
038901
106325080,
133855988 123909
Esbiothrin
28434006
004007
Esfenvalerate
66230044
109303
Ethaboxam
162650773
090205
Ethalfluralin
55283686
113101
16672870
8/15/1994
Ethephon
10/23/2008
1/24/2001
12/2/2003
7/1/1996
3/23/2006
9/14/1994
Page 11

CHEMICAL
CAS NO.*
Ethion
563122
Ethiprole
181587019
PC
CANCER
GroupEEvidenceofNon
058401 carcinogenicityforhumans
Ethofumesate
26225796
110601
Ethoprop
Ethyldipropylthiocarbamate
(EPTC)
13194484
041101
759944
041401
Ethylenethiourea(ETU)
96457
600016
Etofenprox
80844071
128965
Etoxazole
153233911
107091
Famoxadone
131807573
113202
Fenamidone
161326347
046679
Fenamiphos
22224926
100601
Fenarimol
60168889
206600
Fenazaquin
120928098
044501
Fenbuconazole
114369436
129011
Fenbutatinoxide
13356086
Fenhexamide
126833178
REPORT
DATE****
1/26/1994
10/28/2010
2/24/1994
Humans
10/7/1998
toHumans
8/31/1999
GroupBProbableHuman
Carcinogen
7/7/1999
Notlikelytobecarcinogenic
tohumansatdosesthatdo
notalterratthyroidhormone
homeostasis.
toHumans
toHumans
toHumans
GroupEEvidenceofNon
toHumans
ToHumans
GroupCPossibleHuman
Carcinogen
2/8/2006
8/7/2003
4/16/2003
7/12/2002
11/23/1993
9/5/2001
5/15/2007
4/15/1996
GroupEEvidenceofNon
3/2/1993
090209 toHumans
3/4/1999
Page 12

CHEMICAL
CAS NO.*
PC
CANCER
GroupEEvidenceofNon
Humans
toHumans
ToHumans
toHumans
GroupEEvidenceofNon
GroupEEvidenceofNon
SeeZiram
GroupCPossibleHuman
Carcinogen
ToHumans
ToHumans
REPORT
DATE****
Fenitrothion
122145
105901
Fenoxapropethyl
9015569
128701
Fenoxycarb
72490018
125301
Fenpropathrin
39515418
127901
Fenpropidin
67306007
012305
Fenpropimorph
67564914
121402
Fenpyroximate
134098616
129131
Fenthion
55389
053301
Fenvalerate
Ferbam
51630581
14484641
109301
034801
Fipronil
120068373
129121
Flazasulfuron
104040780
119011
Flonicamid
158062670
128016
Florasulam
145701231
129108
79241466
122809 ToHumans
9/19/2008
FluazifopPButyl
7/13/1993
7/29/2013
12/22/97
12/22/2003
6/9/2009
10/19/2005
2/19/1997
3/11/1996
2/10/2003
4/6/2000
7/18/1995
11/16/2005
2/24/2005
5/31/2007
Page 13

CHEMICAL
CAS NO.*
Fluazinam
79622596
Flubendiamide
272451657
Flucarbazonesodium
181274179
Fludioxonil
131341861
Fluensulfone
318290981
Flufenacet(Thiaflumide)
142459583
Flufenoxuron
101463698
Flufenpyrethyl
188489078
Flumethrin
69770452
Flumetralin
Flumetsulam(XRD498)
Flumicloracpentyl
Flumioxazin
Fluometuron
Fluopicolide
Fluopyram
PC
CANCER
3/29/2001
027602 ToHumans
4/3/2008
114009 toHumans
7/19/2000
9/19/1996
05/07/2014
121903 toHumans
7/16/1997
108203 ToHumans
8/15/2006
108853 toHumans
6/8/2003
036007 ToHumans
03/06/12
123001 ToHumans
GroupEEvidenceofNon
98967409
GroupEEvidenceofNon
87546187
103361097,
141490508 129034 toHumans
GroupCPossibleHuman
2164172
035503 Carcinogen
239110157 027412 toHumans
658066354 080302 ToHumans
62924703
REPORT
DATE****
6/21/2007
3/24/1993
9/7/1994
2/22/2001
8/28/1996
12/12/2006
05/08/2014
Page 14

CHEMICAL
CAS NO.*
PC
CANCER
Fluoxastrobin
361377299
028869
Flupyradifurone
951659408
122304
Fluridone
59756604
112900
Fluroxypyr
Fluroxypyracid(seealsoPC
Code128968)
81406373
128968
69377817
128959
Flurprimidol
56425913
125701
Fluthiacetmethyl
117337196
108803
Flutolanil
66332965
128975
Flutriafol
76674210
128940
Fluxapyroxad
907204313
138009
Folpet
133073
081601
Fomesafen
108731700
123802
Fonofos
944229
041701
Forchlorfenuron
68157608
128819
Formasulfuron
173159574
122020
Formetanatehydrochloride
23422539
097301
ToHumans
NotlikelytobeCarcinogenic
toHumans
GroupEEvidenceofNon
ToHumans
toHumans
ToHumans
Humans
GroupEEvidenceofNon
ToHumans
ToHumans:belowadefined
doserange
Notlikelytobecarcinogenic
tohumansatdosesthatdo
notcauseanirritation
responseinthemucosal
epithelium
toHumans
GroupEEvidenceofNon
ToHumans
toHumans
GroupEEvidenceofNon
REPORT
DATE****
1/24/2005
8/5/2014
7/1/1985
6/26/2003
6/26/2003
9/29/2005
11/20/1998
6/9/1994
6/1/2009
6/9/2011
10/13/2010
11/3/2005
11/10/1993
3/11/2008
9/19/2001
5/20/1996
Page 15

CHEMICAL
CAS NO.*
PC
CANCER
FosetylAl
39148248
123301
Fosthiazate
98886443
129022
Furfural
98011
043301
Furilazole(MON13900)
121776338
911596
Furmecyclox
60568050
122601
GammaCyhalothrin
76703623
128807
GentamicinSulfate
1405410
006325
Glufosinateammonium
77182822
128850
Glutaraldehyde
111308
043901
Glyphosate
1071836
417300
Halosulfuronmethyl(MON
1200)
100784201
128721
Haloxyfopmethyl
690806402
125201
Hexaconazole
79983714
HexavalentChromium(CrVI)
18540299
128925
021101;
068302
Hexazinone
51235042
Hexythiazox
78587050
HOE107892
135590919
ToHumans
toHumans
Humans
Humans
GroupBProbableHuman
Carcinogen
toHumans
ToHumans
toHumans
toHumans
GroupEEvidenceofNon
toHumans
GroupBProbableHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
Humans
REPORT
DATE****
4/22/1999
9/15/2003
02/06/2014
10/15/1999
7/3/1985
3/1/2004
3/21/2007
5/17/1999
5/18/2006
10/30/1991
2/26/1998
9/18/1989
1/21/1999
07/01/09
7/27/1994
128849 Humans
9/2/09
811800 toHumans
11/24/1998
Page 16

CHEMICAL
CAS NO.*
Hydramethylnon
67485294
Hydrogencyanamide
420042
Hydroprene
41096462
Imazalil
35554440
Imazamethabenz
81405858
Imazamox
114311329
Imazapic
81334603
PC
CANCER
GroupCPossibleHuman
118401 Carcinogen
GroupCPossibleHuman
014002 Carcinogen
REPORT
DATE****
3/28/1991
9/15/1993
6/8/1995
111901 Humans
12/7/1999
6/11/1987
129171 toHumans
2/27/1997
GroupEEvidenceofNon
9/27/1995
GroupEEvidenceofNon
ToHumans
toHumans
ToHumans
GroupEEvidenceofNon
ToHumans
toHumans
Imazapyr
81334341
128821
ImazaquinAcid
81335377
128848
Imazethapyr
81335775
128922
Imazosulfuron
122548338
118602
Imidacloprid
105827789
129099
Indaziflam
950782862
080818
Indoxacarb
173584446
067710
74884
toHumansatdosesthatdo
notalterratthyroidhormone
000011 homeostasis
11/10/2005
Iodomethane
10/5/1995
10/31/2005
1/31/2002
3/13/2009
11/10/1993
4/22/2010
7/17/2000
Page 17

CHEMICAL
CAS NO.*
PC
CANCER
toHumans
ToHumans
Humans
Humans
GroupEEvidenceofNon
GroupCPossibleHuman
Carcinogen
Humans
toHumans
Humans
ToHumans
REPORT
DATE****
Iodosulfuran
144550367
122021
1/5/2004
Ipoconazole
125225287
125618
Iprodione
36734197
109801
Iprovalicarb
140923177
098359
Isofenphos
25311711
109401
Isophorone
78591
047401
Isopyrazam
881685581
129222
Isoxaben
82558507
125851
Isoxadifenethyl
163520330
823000
Isoxaflutole
141112290
123000
Kasugamycin
6980183
230001
Kathon886
55965849
KBR3023
119515387
Kresoximmethyl
143390890
Lactofen
77501634
5/18/1995
070705 toHumans
6/9/1999
129111 Humans
8/19/1999
LikelytobeCarcinogenicin
HumansatHighDoses.Not
10/17/2006
Lambdacyhalothrin
91465086
GroupDNotclassifiableasto
9/12/2002
5/28/2008
2/26/1998
4/11/2002
1/13/1998
9/2/1999
2/2/2011
10/7/2008
1/29/2001
09/30/97
8/17/2005
Page 18

CHEMICAL
CAS NO.*
PC
CANCER
GroupCPossibleHuman
035506 Carcinogen
REPORT
DATE****
11/29/2001
Lindane
58899
Linuron
330552
Malathion
121755
Maleichydrazide
123331
Mancozeb
8018017
Mandipropamid
374726622
Maneb
MB46513(photodegradateof
Fipronil)
12427382
120067836
MCPA+Salts
94746
MCPBAcid
94815
MecopropP
16484778
Mefenoxam
70630170
Mefluidide
53780340
GroupEEvidenceofNon
GroupBProbableHuman
014504 Carcinogen
036602 ToHumans
GroupBProbableHuman
014505 Carcinogen
600050 toHumans
030501 toHumans
019201 ToHumans
113502 toHumans
114001 ToHumans
108781
7/21/1993
Melamine
11/20/2001
4/28/2000
11/10/1993
7/7/1999
1/21/2009
7/7/1999
12/6/2000
10/29/2003
10/1/2008
3/13/2003
5/17/2000
5/30/2007
Page 19

CHEMICAL
CAS NO.*
Mepanipyrim
110235477
MepiquatChloride
24307264
PC
CANCER
REPORT
DATE****
288203 Humans
4/20/2004
109101 ToHumans
2/19/2003
Meptyldinocap(DE126/Dinocap
II)
131726
036000
Mercaptobenzothiazole,2
149304
051701
Mesosulfuronmethyl
208465218
122009
Mesotrione
104206828
122990
Metaflumizone
139968493
281250
Metalaxyl
57837191
113501
Metaldehyde
108623
053001
Metamsodium
137428
039003
Metconazole
125116236
125619
Methamidophos
10265926
101201
Methidathion
950378
100301
Methiocarb
2032657
Methomyl
16752775
Methoxyfenozide
161050584
Methylbromide
74839
GroupEEvidenceOfNon
CarcinogenicityForHumans
GroupCPossibleHuman
Carcinogen
toHumans
toHumans
ToHumans
GroupEEvidenceofNon
Humans
toHumans
toHumans
GroupCPossibleHuman
Carcinogen
3/17/2009
11/19/1992
3/4/2004
4/12/2001
1/24/2006
4/20/1994
6/23/2005
5/14/2009
4/14/2006
02/12/1998
2/19/1988
3/2/1993
GroupEEvidenceofNon
10/25/1996
121027 toHumans
7/1/1999
053201 ToHumans
06/20/2001
Page 20

CHEMICAL
CAS NO.*
PC
CANCER
REPORT
DATE****
Methylisothiocyanate
6317186
Methylparathion
298000
Metiram
9006422
Thereareinsufficientdatato
characterizethecancerriskof
068103 MITC.
4/30/2009
053501 toHumans
12/1/1997
GroupBProbableHuman
014601 Carcinogen
7/7/1999
240494706
notresultinamitogenic
7/26/2007
109709 response.
Metofluthrin
Metolachlor
51218452
Metrafenone
220899036
GroupCPossibleHuman
108801 Carcinogen
Metribuzin
21087649
101101
Metsulfuronmethyl
74223646
122010
Mevinphos
7786347
015801
MGK264
113484
057001
MGKReplellent326
136458
047201
Molinate
2212671
041402
11/16/1994
7/6/2006
5/16/1995
toHumans
3/14/2002
ToHumans
5/17/2000
GroupCPossibleHuman
Carcinogen
6/7/1995
GroupBProbableHuman
Carcinogen
11/12/2002
12/14/2000
Page 21

CHEMICAL
CAS NO.*
PC
CANCER
MON4660
Monosodiumacid
methanearsonate(MMA)
71526073
600046
2163806
013803
MSMAcalciumsalt
5902954
013806
Myclobutanil
88671890
128857
NAApotassiumsalt
15165794
056003
Naled
300765
Napropamide
15299997
NaptalamSodiumSalt
132672
NapthaleneAcetates
2122705
Nicosulfuron
111991094
Nitrapyrin
1929824
Norflurazon
27314132
Novaluron
116714466
Humans
toHumans
toHumans
GroupEEvidenceofNon
ToHumans
REPORT
DATE****
12/9/1999
7/26/2000
12/14/2000
6/16/1994
3/14/2012
GroupEEvidenceofNon
8/31/1994
103001 ToHumans
7/7/2005
9/7/1994
056008 ToHumans
3/5/2009
GroupEEvidenceofNon
9/1/1998
3/1/2012
GroupCPossibleHuman
105801 Carcinogen
11/2/1990
124002 toHumans
2/4/2004
Page 22

CHEMICAL
CAS NO.*
Orthophenylphenol(seealsoPC
064104)
90437
PC
CANCER
REPORT
DATE****
toHumans(quantificationof
cancerriskisnotrequired
sincetheNOAELselectedfor
thechronicReferenceDose
wouldaddresstheconcerns
fortheprecursorevents
leadingtodevelopmentof
10/12/2005
064103 bladderandlivertumors)
Orthophenylphenol,Sodiumsalt
(seealsoPC064103)
132274
064104
Orthosulfamuron
213464778
108209
Oryzalin
19044883
104201
Oxadiazon
19666309
109001
Oxadixyl
77732093
126701
Oxamyl
23135220
103801
Oxydemetonmethyl
301122
058702
Oxyfluorfen
42874033
111601
toHumans(quantificationof
cancerriskisnotrequired
sincetheNOAELselectedfor
thechronicReferenceDose
wouldaddresstheconcerns
fortheprecursorevents
leadingtodevelopmentof
bladderandlivertumors)
Humans
Humans
GroupCPossibleHuman
Carcinogen
GroupEEvidenceofNon
toHumans
Humans
10/12/2005
10/26/2006
6/25/2003
5/1/2001
1/4/1989
11/5/1996
7/24/1997
4/20/2010
Page 23

CHEMICAL
CAS NO.*
Oxytetracycline
2058460
Oxythioquinox
2439012
Paclobutrazol
76738620
Paradichlorobenzene
106467
PC
CANCER
REPORT
DATE****
12/18/1992
GroupBProbableHuman
054101 Carcinogen
2/15/1996
6/23/1994
061501 ToHumans
6/5/2007
Paranitrophenol
100027
056301
Paraquatdichloride
1910425
061601
Parathion,ethyl
56382
057501
Pebulate
1114712
041403
Pendimethalin
40487421
108501
Penflufen
494793678
100249
Penoxulam
219714962
119031
Pentachloronitrobenzene(PCNB) 82688
056502
Pentachlorophenol
87865
063001
Penthiopyrad
183675823
090112
Permethrin
52645531
109701
5/14/1996
GroupEEvidenceofNon
4/19/2000
GroupCPossibleHuman
Carcinogen
9/11/1991
toHumans
12/7/1998
GroupCPossibleHuman
Carcinogen
7/24/1992
3/30/2011
3/24/2004
GroupCPossibleHuman
Carcinogen
12/18/1992
GroupBProbableHuman
Carcinogen
1/3/1991
10/18/2011
Humans
10/23/2002
Page 24

CHEMICAL
CAS NO.*
Phenmedipham
13684634
PHMB
32289580
Phorate
298022
Phosalone
2310170
Phosmet
732116
Phosphamidon
13171216
Phostebupirim
96182535
PicloramAcid
1918021
PicloramAcidEthylhexylEster
26952205
PicloramAcidPotassiumSalt
2545600
PC
CANCER
REPORT
DATE****
4/28/1993
07/16/2003
GroupEEvidenceofNon
12/30/1993
097701 toHumans
8/12/1999
10/27/1999
GroupCPossibleHuman
018201 Carcinogen
5/31/1989
GroupEEvidenceofNon
4/27/1993
GroupEEvidenceofNon
4/1/1994
GroupEEvidenceofNon
4/1/1994
GroupEEvidenceofNon
4/1/1994
PicloramAcid
TriisopropanolamineSalt
6753475
005102
Picoxystrobin
117428225
129200
Pinoxaden
243973208
147500
Piperonylbutoxide
51036
067501
Pirimicarb
23103982
106101
GroupEEvidenceofNon
AssessmentofHuman
GroupCPossibleHuman
Carcinogen
Humans
4/1/1994
11/15/11
5/18/2005
6/7/1995
7/13/2005
Page 25

CHEMICAL
CAS NO.*
PC
CANCER
REPORT
DATE****
Pirimiphosmethyl
29232937
108102 CannotBeDetermined
1/29/1998
PolymericBetaine
214710346
Potassiumdichromate
7778509
Prallethrin
23031369
Primisulfuronmethyl
86209510
Prochloraz
67747095
Procymidone
32809168
Prodiamine
29091212
Profenofos
41198087
Prohexadione
127277536
InadequateInformationto
103679 AssessCarcinogenicPotential 10/3/2006
SeeHexavalentChromium
068302 (CrVI)
07/01/2009
128722 toHumans
6/27/2003
5/3/1990
GroupCPossibleHuman
128851 Carcinogen
7/1/1988
GroupBProbableHuman
129044 Carcinogen
4/5/1991
GroupCPossibleHuman
110201 Carcinogen
6/10/1991
GroupEEvidenceofNon
2/6/1996
112600 toHumans
4/14/2000
Prometon
1610180
080804
Prometryn
7287196
080805
Pronamide
23950585
101701
Propachlor
1918167
019101
Propamocarbhydrochloride
25606411
119302
Propanil
709988
028201
11/25/1992
GroupEEvidenceofNon
7/26/1994
GroupBProbableHuman
Carcinogen
12/10/2001
Humans
10/16/1997
ToHumans
5/31/2000
6/19/2001
Page 26

CHEMICAL
CAS NO.*
PC
CANCER
Propargite
2312358
097601
Propazine
139402
080808
Propetamphos
31218834
113601
Propiconazole
60207901
122101
Propineb
12071839
522200
Propoxur
114261
047802
PropoxycarbazoneSodium
181274157
122019
Proquinazid
189278124
044502
Prosulfuron
94125345
129031
Prothioconazole
178928706
Pymetrozine
123312890
Pyraclostrobin
175013180
Pyraflufenethyl
129630199
Pyrasulfotole
365400119
Pyrazon
1698608
GroupBProbableHuman
Carcinogen
toHumans
toHumans
GroupCPossibleHuman
Carcinogen
Humans
GroupBProbableHuman
Carcinogen
toHumans
AssessmentofHuman
113961 ToHumans
101103 Humans
099100 toHumans
030090 Humans
069601 ToHumans
REPORT
DATE****
7/23/1992
12/8/2005
10/31/1998
9/11/1992
2/11/2013
6/17/1996
4/6/2004
4/24/2013
1/24/2000
12/31/2007
9/22/1999
2/15/2007
10/8/2002
5/17/2007
7/28/2005
Page 27

CHEMICAL
CAS NO.*
PC
CANCER
Pyrethrins
8003347
069001
Pyridaben
96489713
129105
Pyridalyl
179101816
295149
Pyridate
55512339
128834
Pyrifluquinazon
337458272
555555
Pyrimethanil
53112280
288201
Pyriofenone
688046619
028828
Pyriproxyfen
95737681
129032
Pyrithiobacsodium
123343168
078905
notcausemitogenicrepsonse
inthelivercellproliferation
GroupEEvidenceofNon
ToHumans
ToHumans
ToHumansatlevelsthatdo
notalterrodenthormone
homeostasis
GroupCPossibleHuman
Carcinogen
ToHumans
GroupEEvidenceofNon
GroupCPossibleHuman
Carcinogen
REPORT
DATE****
2/14/2008
5/11/1994
08/03/2004
1/24/2000
6/21/2012
2/11/1997
12/14/2011
8/15/1995
9/5/1995
Pyroxasulfone
447399555
Pyroxsulam
422556089
ToHumansatdosesbelow
thosethatcauseurinary
bladdercalculiformation
resultingincellulardamageof
05/17/2011
090099 theurinarytract
108702 ToHumans
7/12/2007
Quinchlorac
84087014
8/26/1992
Page 28

CHEMICAL
Quinoxyfen
CAS NO.*
124495187
PC
CANCER
REPORT
DATE****
055459 toHumans
1/28/2003
3/17/1988
Humans
5/25/2005
toHumans
2/19/1998
GroupEEvidenceofNon
10/5/1988
ToHumans
7/22/2009
12/2/2003
Humans
5/18/2011
toHumans
3/19/2003
toHumans
4/14/2005
GroupCPossibleHuman
Carcinogen
9/28/2001
Quizalofopethyl
76578148
128711
Resmethrin
10453868
097801
Rimsulfuron
122931480
129009
RoteNone
83794
071003
Saflufenacil(BAS800H)
372137354
118203
SBioallethrin
28434006
004004
Sedaxane
874967676
129223
Sethoxydim
74051802
121001
Simazine
122349
080807
sMetolachlor
87392129
108800
Sodiumbentazon
50723803
GroupEEvidenceOfNon
103901 CarcinogenicityForHumans
15922788
5/16/1995
Sodiumomadine
Spinetoram
Spinosad
1/14/1992
187166401+
187166150 110008 ToHumans
9/20/2007
7/18/2002
131929607 110003 toHumans
Page 29

CHEMICAL
CAS NO.*
PC
CANCER
Spirodiclofen
148477718
124871
Spiromesifen
283594901
024875
Spirotetramat
203313251
392201
Spiroxamine
118134308
120759
Sulfentrazone
122836355
Sulfosate
81591813
Sulfosulfuron
141776321
Sulfoxaflor
946578003
Sulfurylfluoride
2699798
Humans
ToHumans
ToHumans
toHumans
GroupEEvidenceofNon
GroupEEvidenceofNon
REPORT
DATE****
6/10/2004
5/21/2008
3/26/2009
11/14/2003
5/7/1996
7/26/1994
notcausecrystalswith
subsequentcalculiformation
resultingincellulardamageof
12/16/2008
085601 theurinarytract.
4/26/12
078003 toHumans
5/24/2001
Sulprofos
35400432
111501
Sumithrin
26002802
069005
Taufluvalinate
102851069
109302
TCMTB(Busan72)
21564170
035603
Tebuconazole
107534963
128997
GroupEEvidenceofNon
toHumans
ToHumans
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
3/26/1996
5/30/2006
9/29/2005
8/28/1996
9/15/1993
Page 30

CHEMICAL
CAS NO.*
PC
CANCER
REPORT
DATE****
Tebufenozide
112410238
Tebufenpyrad
119168773
GroupEEvidenceofNon
Tebuthiuron
34014181
3/1/1993
Tefluthrin
79538322
128912
Telone
542756
029001
Tembotrione
335104842
012801
Tepraloxydim
149979419
121005
Terbacil
5902512
012701
Terbufos
13071799
105001
Terbuthylazine
5915413
080814
Terbutryn
886500
080813
Terrazole
2593159
084701
Tetrachlorvinphos
961115
083701
ToHumans
GroupBProbableHuman
Carcinogen
AssessmentofHuman
GroupEEvidenceofNon
GroupEEvidenceofNon
8/29/1994
7/15/2002
5/30/2012
3/19/2002
5/22/2007
2/27/2001
9/30/1994
3/9/1994
8/24/1994
GroupCPossibleHuman
Carcinogen
3/3/1988
GroupBProbableHuman
Carcinogen
6/29/1999
Humans
3/7/2002
Page 31

CHEMICAL
CAS NO.*
PC
CANCER
REPORT
DATE****
ToHumansatlevelsthatdo
notcauseincreasedcell
4/2/2013
120603 proliferationintheliver
Tetraconazole
112281773
Tetramethrin
7696120
Thiabendazole
148798
Thiacloprid
111988499
Thiamethoxam
153719234
Thiazopyr(MON13200)
117718602
Thidiazuron
51707552
Thiencarbazonemethyl
317815831
Thifensulfuronmethyl
79277273
GroupCPossibleHuman
069003 Carcinogen
HumansatHighDoes;Not
014019 Humans
060109 toHumans
120301 ToHumans
notcauseurothelium
015804 cytotoxicity
128845 ToHumans
Thiobencarb(Bolero)
28249776
6/10/1996
Thiocyclamhydrogenoxalate
31895224
Thiodicarb
59669260
Thiophanatemethyl
23564058
12/11/1989
3/8/2002
10/31/2012
6/13/2005
12/6/2007
8/31/2005
2/29/2008
12/12/2006
9/15/1994
GroupBProbableHuman
114501 Carcinogen
6/10/1996
102001 Humans
8/24/1999
Page 32

CHEMICAL
CAS NO.*
PC
CANCER
Thiram
Tolclofosmethyl
137268
57018049
079801
128905
Tolfenpyrad
129558765
090111
Tolyfluanid
731271
309200
toHumans
NotRequired(nonfood)
ToHumans
Humans
toHumansatDosesthatDo
NotAlterRatThyroid
HormoneHomeostasis
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
GroupEEvidenceofNon
toHumans
GroupCPossibleHuman
Carcinogen
Humans(HighDoses);Not
Humans(LowDoses)
Topramezone
210631688
123009
Tralkoxydim
87820880
121000
Triadimefon
43121433
109901
Triadimenol
55219653
127201
Triallate
2303175
078802
Triasulfuron
82097505
128969
Triazamate
112143825
128100
Tribenuronmethyl
101200480
128887
Tribufos
78488
074801
14275571
Tributyltinmaleate
REPORT
DATE****
4/14/2003
3/22/2012
06/03/2010
6/18/2002
5/19/2005
6/30/2004
12/4/1996
1/29/1988
1/12/1994
2/27/1991
12/1/1997
7/14/1989
5/22/1997
3/31/2005
Page 33

CHEMICAL
Trichlorfon
CAS NO.*
52686
PC
CANCER
REPORT
DATE****
Humans(HighDoses),Not
057901 Humans(LowDoses)
7/15/1999
Triclopyr
55335063
116001
Triclosan
3380345
054901
Tridiphane
58138082
123901
Trifloxystrobin
141517217
129112
Trifloxysulfuron
290332104
119009
Triflumizole
68694111
128879
Trifluralin
1582098
036101
Triflusulfuronmethyl
126535157
129002
Triforine
26644462
107901
TrinexapacEthyl
95266403
112602
Triphenyltinhydroxide(TPTH)
76879
083601
Triticonazole
131983727
125620
Troysanpolyphase(IPBC)
55406536
107801
UDMH
57147
600018
UMP488(PAL6000)
111578326
129025
5/9/1996
ToHumans
1/4/2008
GroupCPossibleHuman
Carcinogen
4/22/1986
toHumans
6/16/1999
toHumans
7/22/2003
GroupEEvidenceofNon
8/10/1993
GroupCPossibleHuman
Carcinogen
4/11/1986
GroupCPossibleHuman
Carcinogen
5/28/1996
6/29/2004
ToHumans
9/5/2008
GroupBProbableHuman
Carcinogen
5/24/1990
toHumans
6/15/2006
toHumans
12/4/1996
GroupBProbableHuman
Carcinogen
7/26/1991
GroupEEvidenceofNon
5/6/1994
Page 34

CHEMICAL
CAS NO.*
PC
CANCER
Uniconazole
83657221
128976
Vinclozolin
50471448
113201
ZetaCypermethrin
52315078
129064
Ziram
137304
034805
Zoxamide
156052685
101702
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
GroupCPossibleHuman
Carcinogen
toHumans
REPORT
DATE****
10/11/1990
6/20/2000
9/27/1988
2/6/2003
2/7/2001
*CAS No.: a chemical identifier designated by the Chemical Abstracts Service

**PC Code: a unique chemical identifier used by the Office of Pesticide Programs
***Cancer Classification: Simple descriptors used to express conclusions regarding the carcinogenic hazard potential of a
chemical based on all relevant information, which is usually laboratory studies. These phases changed over time, as the
Agency's guidance for carcinogenicity assessment was updated and revised.
****Report: Date of the Carcinogen Assessment Review Committee (CARC) report. The CARC report date does not
necessarily reflect the date of the pesticide risk assessment. For example, all existing pesticide tolerances that were in place as
of August 1996 were re-assessed for their health risks by August 2006 as required by the Food Quality Protection Act, and if
there was no new information on carcinogenicity, the compound was not re-evaluated by the CARC.
Page 35

Chemicals Evaluated For Carcinogenic Potencial Office of Pesticides Progras US-EPA

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Chemicals Evaluated For Carcinogenic Potencial Office of Pesticides Progras US-EPA

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October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

What does EPA consider in its review of cancer risk?

laboratory animal findings,

Why are there several different cancer classifications in the list?

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential

Annual Cancer Report October 2, 2014

Chemicals Evaluated for Carcinogenic Potential