PAPER

INTEGRATED
DESIGN AND
CONTROL
APROACH

A Robust and
Efficient
Mixed-Integer
Non-Linear
Dynamic
Optimization
Approach for
Simultaneous
Design
And Control
[8]

Discretization of the
manipulated and
controlled variables of the
MIDO problem into a
mixed-integer nonlinear
programming (MINLP)

Efficient addressing in a
systematic way of the
solution of the
simultaneous design a
control problem

A system of two
series connected
continuous stirred
tank reactors, where
first order reaction
takes a place.

Metodolog
a para la
integracin
diseo control en
el espacio
de estados
[1]

Based on modern
control theory, which
evaluate the
controllability in the
state space, and uses
phenomenological
based models and,
nonlinear constrained
optimization

It defines the local

practical controllability
concept and it
develops metrics to
evaluate it.

A CSTR reactor
and a Vaporizer.

It's performed a
distribution analysis on
the worst-case variability
and the results was used
for evaluate the process
constraints, the systems
dynamic performance
and the process
economics

The methodology is
computationally efficient
and it is a practical tool

Continuous stirred
tank reactor

Analysis cost function

trough worst-case closedloop variability is used for
dynamic performance;
NLP and MINLP
formulations are
proposed

It takes into account both

centralized and
decentralized control
strategies.

Wastewater
treatment industrial
plant.

Integration
of process
design and
control: A
review [2]

Integrated design and

control methods,
evolution, advantage
and disadvantage.

It suggests topics for

future investigation.

Simultaneous
design and
MPC-based
control for
dynamic
systems

A stochastic-based worstcase variability index is

proposed for determining
the dynamic feasibility
under uncertainty and a
multivariable model

Optimal
design and
control of
dynamic
systems
under
uncertainty: A
probabilistic
approach [15]
An MPCbased control
structure
selection
approach for
simultaneous
process and
control
design [16]

CONTRIBUTION

Its able to maintain

dynamic feasibility
when the system is
subject to single and
multiple disturbances

CASE STUDY

-Wastewater
treatment industrial
plant

under
uncertainty: A
stochastic
approach [17]

predictive control (MPC)

is used for control
scheme.

Integrated
design and
control of
chemical
processes
Part I:
Revision and
classication
[3]

It presents a
comprehensive
classification of design
and control integrated
methods, integrated
optimization methods
and mathematical
algorithms for resolve
it.

Characterization by kind
evaluation methods
controllability, design
problem, uncertain and
perturbations,
optimization methods
and algorithms for solve
it.

--

10) Bibliography
1.
2.
3.
8.
15.
16.
17.

Ochoa, S., Metodologa para la Integracin Diseo-Control en el espacio de

Estados. M. Sc. Tesis. Universidad Nacional de Colombia, 2005.
Sharifzadeh, M., Integration of process design and control: A review.
Chemical Engineering Research and Design, 2013. 91(12): p. 2515-2549.
Vega, P., et al., Integrated design and control of chemical processespart i:
revision and classification. Computers & Chemical Engineering, 2014.
Flores-Tlacuahuac, A. and L.T. Biegler, A robust and efficient mixed-integer
non-linear dynamic optimization approach for simultaneous design and
control. Computer Aided Chemical Engineering, 2005. 20: p. 67-72.
Ricardez-Sandoval, L.A., Optimal design and control of dynamic systems
under uncertainty: A probabilistic approach. Computers & Chemical
Engineering, 2012. 43: p. 91-107.
Gutierrez, G., et al., An MPC-based control structure selection approach for
simultaneous process and control design. Computers & Chemical
Engineering, 2014. 70: p. 11-21.
Bahakim, S.S. and L.A. Ricardez-Sandoval, Simultaneous design and MPCbased control for dynamic systems under uncertainty: A stochastic
approach. Computers & Chemical Engineering, 2014. 63: p. 66-81.