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<title>Europe PMC Search: Arterial Interventions Aneurysm [All citations]</
title>
<link>http://europepmc.org/search/?page=1&amp;amp;query=Arterial+Interventio
ns+Aneurysm+&amp;source=rss</link>
<description>The first 25 results of your Europe PMC Search</description>
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<image>
<title>UKPMC</title>
<url>http://europepmc.org/images/logo.jpg</url>
<link>http://europepmc.org/search/?page=1&amp;amp;query=Arterial+Intervent
ions+Aneurysm+&amp;source=rss</link>
<description>Europe PubMed Central (UKPMC) - A unique, free, information r
esource for biomedical and health researchers</description>
</image>
<item>
<title>Endovascular treatment of fusiform intracranial vertebral artery an
eurysms using reconstructive techniques.</title>
<link>http://europepmc.org/abstract/MED/24078647?source=rss</link>
<description>OBJECTIVE: To report our single center experience in the trea
tment of fusiform aneurysms involving the intracranial vertebral arteries using
reconstructive endovascular techniques. PATIENTS AND METHODS: The neurointervent
ional database of our institution was retrospectively reviewed from June 2010 to
February 2013. Patients who underwent endovascular treatment of fusiform intrac
ranial vertebral artery aneurysms using reconstructive techniques were included
in the analysis. Clinical presentation, size, reconstructive technique used, pro
cedural complication, and clinical and angiographic follow-ups were included in
the analysis. RESULTS: Nine patients, aged 41-76 years (mean 54.8 years), were inclu
ded. Mean angiographic diameter of unruptured aneurysms was 8.4 mm (range 4-14) wh
ile ruptured aneurysms averaged 6 mm (range 5-7 ). Two patients (two women) presente
d with acute subarachnoid hemorrhage (SAH). One patient with a large partially t
hrombosed aneurysm was treated with stent reconstruction requiring deployment of
two stents (no coiling). There was one asymptomatic procedural complication (no
n-flow limiting cervical vertebral dissection). All patients had good clinical o
utcomes (modified Rankin Scale score of 0 or 1) including the two patients that p
resented with SAH (Hunt and Hess grades 2 and 3). There were no late hemorrhages
at a mean clinical follow-up of 12 months (6-24 months). Eight patients had angiogr
aphic follow-up (6-18 months, mean 10.5 months) and six demonstrated aneurysm occlus
ion with complete vessel reconstruction at the angiographic follow-up. CONCLUSIO
NS: The use of reconstructive techniques in the endovascular treatment of unrupt
ured fusiform intracranial vertebral artery aneurysms is feasible, safe, and eff
ective in the mid term. In patients presenting with SAH, however, the safety and
effectiveness of these techniques remain unclear.</description>
<author>Dabus G, Lin E, Linfante I</author>
</item>
<item>
<title>Distinct trends of pulsatility found at the necks of ruptured and u
nruptured aneurysms.</title>

<link>http://europepmc.org/abstract/MED/23416784?source=rss</link>
<description>BACKGROUND: Aneurysm hemodynamics has been shown to be an imp
ortant factor in aneurysm growth and rupture. Although pulsatility is essential
for blood flow and vascular wall function, studies of pulsatile flow properties
in brain aneurysm disease are limited. OBJECTIVE: To investigate differences in
pulsatility within a group of ruptured and unruptured aneurysms by implementing
patient-specific pulsatile flow simulation. METHODS: 41 of 311 internal carotid
artery aneurysms were selected from an aneurysm database (29 unruptured and 12 r
uptured) and used for patient-specific hemodynamic simulations of pulsatile flow
. Flow pulsatility changes in ruptured and unruptured groups were analyzed by co
mparing different components of blood flow. Pulsatility index (PI) was used to q
uantify the pulsatility of blood flow in each group at the aneurysm neck, body,
dome, and parent artery. RESULTS: Within the parent artery, PI did not significa
ntly differ between ruptured and unruptured groups (0.58). Within unruptured ane
urysms, values of PI similar to that of the parent artery were found (0.61). Tre
nds of significantly higher PI (1.99) were found within ruptured aneurysms (p&lt
;0.001). These differences were localized at the aneurysm neck, where PI in rupt
ured (1.93) and unruptured (0.59) aneurysms was significantly different (p&lt;0.
001). CONCLUSIONS: A trend towards a lower PI, similar to that in the parent art
ery, was found in unruptured aneurysms, while ruptured aneurysms followed a tren
d of higher pulsatility. The difference was significant at the aneurysm neck, in
dicating that pulsatility and this location may be important aspects of aneurysm
rupture and a useful predictor of the risk of aneurysm rupture.</description>
<author>Patti J, Viuela F, Chien A</author>
</item>
<item>
<title>The 'one and a half round microcatheterization technique' for stent
-assisted coil embolization of intracranial aneurysm: technical case series.</ti
tle>
<link>http://europepmc.org/abstract/MED/23723289?source=rss</link>
<description>BACKGROUND: Stent-assisted coil embolization is useful for wi
de-necked, large and giant aneurysms, and is effective for avoiding coil herniat
ion. However, the mobility of the microcatheter is often restricted, resulting i
n deviated or unbalanced coiling. In order to prevent this insufficient coiling,
the authors devised a method for microcatheterization, the 'one and a half roun
d microcatheterization technique'. This technique is based on the formation of a
one and a half round loop by the microcatheter along the aneurysmal wall. Furth
ermore, this technique can be supplemented with the double-catheter technique. M
ETHODS: From July 2010 to July 2012, the authors used this technique for 20 aneu
rysms in 20 patients (6 men and 14 women; mean age 61.7 years). The one and a ha
lf round microcatheterization technique was used alone in 12 cases and was suppl
emented with the double-catheter technique in eight. The clinical and angiograph
ic results were retrospectively evaluated. RESULTS: The average aneurysm size wa
s 16.7 mm; 12 aneurysms (60%) were located at the internal carotid artery, 5 (25
%) at the basilar artery and 3 (15%) at the vertebral artery. Immediate angiogra
phic results showed complete obliteration in 6 aneurysms (30%) and residual neck
in 10 (50%), leaving 4 residual aneurysms (20%). This technique was useful and
acceptably safe for packing the aneurysmal sac entirely. During an average follo
w-up of 20.5 months, 13 of the 18 aneurysms (72%) were stable or had improved, a
lthough 3 (16%) required retreatment. CONCLUSIONS: The one and a half round micr
ocatheterization technique provides dense coil packing for stent-assisted emboli
zation of large or giant aneurysms.</description>
<author>Miyachi S, Matsubara N, Izumi T, Asai T, Yamanouchi T, Ota K, Oda
K, Wakabayashi T</author>
</item>
<item>
<title>Acute phase endovascular intervention on a pseudoaneurysm formed du
e to rupture of an anterior communicating artery aneurysm.</title>
<link>http://europepmc.org/abstract/MED/24565758?source=rss</link>
<description>A 79-year-old woman presented with a subarachnoid hemorrhage.

Angiography revealed pseudoaneurysm formation due to rupture of a true saccular


anterior communicating artery aneurysm. Coil embolization, limited to the true
aneurysm, was performed successfully with a favorable clinical outcome. This pro
cedure can be considered as an alternative treatment option for similar aneurysm
s in cases where surgical clipping is contraindicated.</description>
<author>Ito H, Morishima H, Onodera H, Wakui D, Uchida M, Sase T, Oshio K,
Tanaka Y</author>
</item>
<item>
<title>Reconstructive endovascular treatment of vertical stenosis associat
ed with adjacent aneurysm at the same arterial anatomic segment.</title>
<link>http://europepmc.org/abstract/MED/23849750?source=rss</link>
<description>One case had a symptomatic vertebral artery stenosis coupled
with a coincidental unruptured cerebral aneurysm at the same arterial anatomic s
egment. And another case had an asymptomatic vertebral artery stenosis coupled w
ith a ruptured cerebral aneurysm at the same arterial anatomic segment. They und
erwent intracranial stenting. Both lesions were treated successfully and neither
complications nor strokes occurred after the procedures. Covered stent placemen
t in an intracranial stenosis with an adjacent ruptured or unruptured aneurysm m
ay be a feasible method.</description>
<author>Guo XB, Song LJ, Guan S</author>
</item>
<item>
<title>The Multilayer Flow Modulator Stent (MFM) for the treatment of arte
rial aneurysms.</title>
<link>http://europepmc.org/abstract/MED/25267226?source=rss</link>
<description>Arterial Aneurysms are traditionally treated surgically but t
he operative risks remain high. More and more interventional procedures are prop
osed: - For Visceral and Peripheral aneurysms covered stents, endografts, coils
can be used, but these techniques have a lot of disadvantages, drawbacks. Aneury
sms with collateral branches cannot be treated with covered stents. The stent ca
n occlude these collaterals leading to severe complications. - For Aortic Aneury
sms (AAA, TAAA) hybrid techniques, endografts have been used to reduce morbidity
/mortality rates encountered with surgical procedures. Recently new techniques h
ave been developed: branched grafts, fenestrated grafts, chimney techniques. The
technical success of these techniques is high but the complications rate is alw
ays high despite experienced, skilled operators: high morbidity/mortality rates,
endoleaks, renal impairment, neurological complications with paraplegiadue to s
pinal cord ischemia. For these reasons we used a new concept of stent, the Multi
layer Flow Modulator Stent (MFM) to treat any aneurysm. This MFM is a 3 Dimensio
nal braided tube made of several interconnected layers without any covering. Our
earliest tests, through studies as theoritical simulation, computerized Fluid d
ynamics, Molecular Modelization and through in vitro and in vivo tests demonstra
te that this MFM reduces the velocity in the aneurysmal sac up to 90% by modifyi
ng the hemodynamic conditions. A saccular aneurysm without collateral branch wil
l thrombose quickly. If a collateral branch is present the flow is directed towa
rds this branch leading to progressive shrinkage of the aneurysm. In a Fusiform
Aneurysm (AAA, TAAA) the MFM eliminates the damaging flow vortex pressure, lamin
ates and redirects its flow along the wall, directs and increases the flow in th
e collateral branches which remain patent. As demonstrated in animal and human s
tudies this MFM preserves the collateral branches allowing the possibility to co
ver any artery without compromising the flow (renal, digestive arteries, supra a
ortic vessel). We will report our experience with the new device, summarize the
main literature data and compare the results obtained with this stent, with the
most recent techniques such as fenestrated, branched grafts, chimney technique.
If we respect hard endpoints, important guidelines, technical points of stent im
plantation, the results are very promising and the MFM seems to be a breakthroug
h to treat any aneurysm.</description>
<author>Henry M, Benjellou A, Henry I</author>
</item>

<item>
<title>Hepatic artery aneurysm causing obstructive jaundice.</title>
<link>http://europepmc.org/abstract/MED/25202666?source=rss</link>
<description>Hepatic artery aneurysms (HAA) are rare and represent 14-20%
of all visceral artery aneurysms. The vast majority of HAA are single and are lo
cated extrahepatically and nowadays about half of the HAA are iatrogenic, as a c
onsequence of the widespread use of interventional diagnostic and therapeutic bi
liary procedures. Abdominal trauma, infection, inflammation and atherosclerosis
are other common predisposing factors. Most of the HAA are asymptomatic, and 6080% of the patients are diagnosed when the aneurysm has complicated with rupture
and bleeding, obstructive jaundice due to external bile duct compression or rup
ture of the HAA into the biliary tree with clots occluding the lumen. We present
a case of HAA presented with obstructive jaundice. Irrespective of clinical pre
sentation the diagnosis of HAA is always based on imaging studies.</description>
<author>Julianov A, Georgiev Y</author>
</item>
<item>
<title>Ruptured gastric artery aneurysm: An uncommon manifestation of micr
oscopic polyangiitis.</title>
<link>http://europepmc.org/abstract/MED/25253973?source=rss</link>
<description>Gastric artery aneurysm is a rare and lethal condition, and i
s caused by inflammatory or degenerative vasculopathies. We describe herein the
clinical course of a patient with a ruptured gastric artery aneurysm associated
with microscopic polyangiitis. Absence of vasculitic changes in the aneurysm res
ected and negative results of autoantibodies interfered with our diagnostic proc
ess. We should have adopted an interventional radiology and initiated steroid th
erapy promptly to rescue the patient.</description>
<author>Ikura Y, Kadota T, Watanabe S, Arimoto A, Nishioka E</author>
</item>
<item>
<title>X-microstenting and transmesh coiling in the management of wide-nec
ked tent-like anterior communicating artery aneurysms.</title>
<link>http://europepmc.org/abstract/MED/24291480?source=rss</link>
<description>Anterior communicating artery (AcomA) aneurysms frequently ha
ve wide necks and an irregular shape, incorporate parent vessels, and are associ
ated with significant variations in vascular anatomy. Safe and complete endovasc
ular occlusion of these aneurysms usually requires the assistance of combined ap
proaches using balloons and stents in an individually tailored strategy. We desc
ribe a technique for X-configured stent-assisted coiling in the management of a
small tricuspid tent-like wide-necked AcomA aneurysm by means of two crossed nit
inol self-expandable Leo+ Baby stents (Balt Therapeutics, Montmorency, France) f
ollowed by "in stent" transmesh coiling. The addition of a low-profile stent int
o the neurointerventional armamentarium will substantially enhance our capabilit
y to treat previously uncoilable tent-like AcomA aneurysms.</description>
<author>Cohen JE, Melamed I, Itshayek E</author>
</item>
<item>
<title>Aneurysm pressure measurement before and after placement of a Pipel
ine stent: feasibility study using a 0.014 inch pressure wire for coronary interve
ntion.</title>
<link>http://europepmc.org/abstract/MED/24871764?source=rss</link>
<description>Flow-diverting stents have provided a new endovascular capaci
ty to reconstruct an intracranial aneurysm with its diseased parent artery. The
results of first-generation flow diversion stents have been encouraging, with ev
en large or giant treated aneurysms achieving complete angiographic occlusion at
12-month follow-up. Numerous clinical reports have described a slow progressive
thrombosis pattern and gradual increase in rate of complete aneurysm obliterati
on over time. Despite promising early results, some complications specific to fl
ow-diverting stents have been encountered. Chief among them is delayed aneurysm
rupture. This complication did not emerge with stent-assisted coil embolization

of intracranial aneurysms, and the underlying cause has not been established. Ho
wever, new evidence suggests that persistent, or even increased, aneurysm pressu
re after stent placement may play a role in some delayed ruptures. We sought to
evaluate this phenomenon by measuring intrasaccular pressure before and after st
ent placement using two different 0.014 inch coronary pressure measurement wires.
Two patients with giant internal carotid artery aneurysms treated with flow-dive
rting stents were evaluated. Before and after stent deployment, intrasaccular an
eurysm and systemic arterial pressures were recorded for 60 s and compared. In bot
h cases, intrasaccular pressure measurement with the use of 0.014 inch pressure wi
re system was feasible; the pressure wires could be pushed out of the microcathe
ter placed in the aneurysms without friction or unexpected microcatheter motion.
Despite successful flow-diverting stent deployment and angiographic flow divers
ion effects with excellent wall opposition across the aneurysm necks, there was
no significant difference between intrasaccular and systemic pressures.</descrip
tion>
<author>Tateshima S, Jones JG, Mayor Basto F, Vinuela F, Duckwiler GR</aut
hor>
</item>
<item>
<title>Association of aneurysms and variation of the A1 segment.</title>
<link>http://europepmc.org/abstract/MED/23612892?source=rss</link>
<description>BACKGROUND AND PURPOSE: Previous studies have described a cor
relation between variants of the circle of Willis and pathological findings, suc
h as cerebrovascular diseases. Moreover, anatomic variations of the anterior cer
ebral artery (ACA) seem to correspond to the prevalence of aneurysms in the ante
rior communicating artery (ACoA). The aim of this study was to assess the preval
ence of aneurysms in patients with anatomical/morphological variations of the ci
rcle of Willis. METHODS: We retrospectively analyzed 223 patients who underwent
cerebral angiography between January 2002 and December 2010 for aneurysm of the
ACoA. Diagnostic imaging was reviewed and statistically evaluated to detect circ
le of Willis anomalies, aneurysm size, and rupture. 204 patients with an unrelat
ed diagnosis served as the control group. RESULTS: Variations of the A1 segment
occurred significantly more frequently in the aneurysm group than in the control
group. Mean aneurysm size in patients with grades I and III hypoplasia or aplas
ia was 6.58 mm whereas in patients with grade II hypoplasia it was 7.76 mm. CONC
LUSIONS: We found that variations in the A1 segment of the ACAs are correlated w
ith a higher prevalence of ACoA aneurysms compared with patients with a symmetri
c circle of Willis.</description>
<author>Krasny A, Nensa F, Sandalcioglu IE, Gricke SL, Wanke I, Gramsch C,
Sirin S, Oezkan N, Sure U, Schlamann M</author>
</item>
<item>
<title>Rare saccular aneurysm in a medial type persistent trigeminal arter
y trunk and literature review.</title>
<link>http://europepmc.org/abstract/MED/23851942?source=rss</link>
<description>PURPOSE: We report an extremely rare case of saccular aneurys
m in the left medial type persistent trigeminal artery (PTA) trunk and discuss i
ts clinical importance. MATERIALS AND METHODS: A 77-year-old woman who had sympt
om suggestive of vertebrobasilar insufficiency underwent cerebral magnetic reson
ance (MR) imaging and non-contrast three dimensional time-of-flight MR angiograp
hy (3D TOF MRA) using a 3 T scanner. RESULTS: 3D TOF MRA images revealed a left
medial type PTA originated from the left internal carotid artery C5 portion, thr
ough cavernous sinus and connected to the basilar artery with a saccular aneurys
m in the mid portion of its trunk. The basilar artery (BA) under the union was h
ypoplastic. The bilateral posterior communicating arteries were absent. CONCLUSI
ON: To our knowledge, this is the first report of a medial type PTA associated w
ith a saccular aneurysm in the PTA trunk. Being aware of this is crucial in clin
ical, because they can influence surgical and interventional procedures.</descri
ption>
<author>Bai M, Guo Q, Sun Y</author>

</item>
<item>
<title>Resolution of trigeminal neuralgia by coil embolization of a persis
tent primitive trigeminal artery aneurysm.</title>
<link>http://europepmc.org/abstract/MED/24610143?source=rss</link>
<description>The persistent primitive trigeminal artery (PTA) is a rare an
astomosis between the carotid artery and basilar artery. While most PTAs are asy
mptomatic, lateral variants can occasionally compress the trigeminal nerve and p
recipitate trigeminal neuralgia. Aneurysms of the PTA are exceptionally rare in
the literature and have not previously been associated with trigeminal neuralgia
. We present the first case of an aneurysm of the PTA causing trigeminal neuralg
ia. The patient underwent coil embolization of the aneurysm which relieved her s
ymptoms. We propose embolization as a viable therapeutic option for the resoluti
on of trigeminal neuralgia when the condition is secondary to irritation by the
high velocity pulsatile flow of an aneurysm.</description>
<author>Ladner TR, Ehtesham M, Davis BJ, Khan IS, Ghiassi M, Ghiassi M, Si
nger RJ</author>
</item>
<item>
<title>Endovascular coiling versus parent artery occlusion for treatment o
f cavernous carotid aneurysms: a meta-analysis.</title>
<link>http://europepmc.org/abstract/MED/24658655?source=rss</link>
<description>BACKGROUND AND PURPOSE: Endosaccular coil embolization and pa
rent artery occlusion (PAO) are established endovascular techniques for treatmen
t of cavernous carotid aneurysms. We performed a systematic review of published
series on endovascular treatment of cavernous carotid aneurysms to determine out
comes and complications associated with endovascular coiling and PAO of cavernou
s carotid artery aneurysms. METHODS: In September 2013, we conducted a computeri
zed search of MEDLINE and EMBASE for reports on endovascular treatment of intrac
ranial cavernous carotid aneurysms from January 1990 to August 2013. Comparisons
were made in periprocedural complications and outcomes between coiling and PAO
patients who did not receive bypass. Event rates were pooled across studies usin
g random effects meta-analysis. RESULTS: 20 studies with 509 patients and 515 an
eurysms were included in this systematic review. Aneurysm occlusion rates at &gt
;3 months after operation were significantly higher in the PAO without bypass gr
oup (93.0%, 95% CI 86.0 to 97.0) compared with the coiling group (67.0%, 95% CI
55.0 to 77.0) (p&lt;0.01). Retreatment rates were significantly lower in the PAO
without bypass group (6.0%, 95% CI 2.0 to 12.0) compared with the coiling group
(18.0%, 95% CI 12.0 to 26.0) (p=0.01). Coiling patients had a similar morbidity
rate (3.0%, 95% CI 2.0 to 6.0) compared with PAO without bypass patients (7.0%,
95% CI 3.0 to 12.0) (p=0.13). Coiling patients had a similar mortality rate (0.
0%, 95% CI 0.0 to 6.0) compared with PAO without bypass patients (4.0%, 95% CI 1
.0 to 9.0) (p=0.68). CONCLUSIONS: Evidence from non-comparative studies suggests
that traditional endovascular options are highly effective in treating cavernou
s sinus aneurysms. PAO is associated with a higher rate of complete occlusion. P
eriprocedural morbidity and mortality rates are not negligible, especially in pa
tients receiving PAO.</description>
<author>Turfe ZA, Brinjikji W, Murad MH, Lanzino G, Cloft HJ, Kallmes DF</
author>
</item>
<item>
<title>Flow diverter stents for unruptured saccular anterior circulation p
erforating artery aneurysms: safety, efficacy, and short-term follow-up.</title>
<link>http://europepmc.org/abstract/MED/25051964?source=rss</link>
<description>BACKGROUND: Anterior circulation perforating artery aneurysms
including anterior choroidal artery and lenticulostriate artery aneurysms are r
are. Injury to these vessels can lead to severe debilitating symptoms. OBJECTIVE
: To present a new approach to treatment using flow diversion technology. METHOD
S: Patients treated with a Pipeline embolization device (PED) for perforator art
ery aneurysms at our institution between June 2012 and May 2013 were identified

and included in our retrospective analysis. We evaluated patient vascular risk f


actors; family history of aneurysms; aneurysm characteristics; National Institut
es of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) on admission;
and angiography follow-up and patient clinical outcome at discharge, 6 months, and
1 year. RESULTS: We included four patients with a mean age of 59.8 years. Two patie
nts had a positive family history of aneurysms. Patient vascular risk factors in
cluded smoking, dyslipidemia, and hypertension. All patients presented with a NI
HSS and mRS of 0 on admission. Aneurysms were located at the anterior choroidal
(n=2) or lenticulostriate artery (n=2) and were treated with a single PED. No pe
riprocedural or postprocedural complications occurred. The patients were dischar
ged with no change in NHISS or mRS score. Six-month and 1-year follow-up angiogr
aphy showed complete aneurysm occlusion. Mild intimal hyperplasia was seen in 2
cases at 6 months, but was resolved at the 1-year follow-up. No re-treatment was n
ecessary. NIHSS and mRS remained 0 at follow-up time points. CONCLUSIONS: Our pr
eliminary results show that flow diversion technology is an effective and safe t
herapy for complex, hard-to-treat aneurysms in perforating arteries. Larger stud
ies with long-term follow-up are needed to validate our promising results.</desc
ription>
<author>Khn AL, Hou SY, Perras M, Brooks C, Gounis MJ, Wakhloo AK, Puri AS<
/author>
</item>
<item>
<title>Resolution of bilateral moyamoya associated collateral vessel aneur
ysms: Rationale for endovascular versus surgical intervention.</title>
<link>http://europepmc.org/abstract/MED/25071939?source=rss</link>
<description>BACKGROUND: Management of aneurysms associated with deep coll
ateral vessels in moyamoya disease is challenging both from an endovascular and
a surgical standpoint. Difficulties with access or localization, and compromise
of the collateral circulation with subsequent ischemia are the primary concerns,
making direct obliteration potentially unfeasible or risky. Alternatively, supe
rficial temporal artery-middle cerebral artery bypass is another potential strat
egy for resolution of these aneurysms. CASE DESCRIPTION: Presented are the findi
ngs and management for a patient with moyamoya disease and bilateral deep collat
eral vessel aneurysms, successfully treated with endovascular obliteration follo
wing a right-sided hemorrhage and subsequently with bypass for an unruptured but
growing contralateral aneurysm. CONCLUSIONS: A rationale and approach to manage
ment is outlined, as derived from review of the current literature and the illus
trative case with bilateral collateral vessel aneurysms.</description>
<author>Amin-Hanjani S, Goodin S, Charbel FT, Alaraj A</author>
</item>
<item>
<title>Treatment of rabbit carotid aneurysms by hybrid stents (microporous
thin polyurethane-covered stents): preservation of side-branches.</title>
<link>http://europepmc.org/abstract/MED/23887877?source=rss</link>
<description>OBJECTIVE: We sought to determine the patency of normal arter
ial branches from the covered segments of an artery after stenting. BACKGROUND:
Most intracranial aneurysms occur at arterial branching points (bifurcations, si
de-branches, or perforators). The post-stenting patency of normal arterial branc
hes from the covered segments of the artery is important. We have previously dev
eloped a hybrid stent with micropores to prevent early parent artery occlusion b
y more early endothelialization, and mid- to long-term parent artery stenosis by
control of intimal hyperplasia after aneurysm occlusion. METHODS: We created an
eurysms in 10 rabbits by distal ligation and intraluminal incubation of elastase
within an endovascularly trapped proximal segment of the common carotid artery.
All animals were treated with hybrid stents having micropores. Four animals wer
e observed for one month and three each for three and 12 months. The patency of
the side-branches of the subclavian artery was evaluated angiographically and in
some cases, histologically. RESULTS: Aneurysms were completely occluded at all
time points other than 12 months. The subclavian artery and brachiocephalic arte
ry were patent, without significant stenosis. All the side-branches of the subcl

avian artery detected on the preoperative angiogram remained patent at the final
assessment. CONCLUSION: The use of hybrid stents for aneurysm repair and side-b
ranch patency seems to be effective, as per the long-term results obtained in an
animal model.</description>
<author>Nishi S, Nakayama Y, Ishibashi-Ueda H, Yoshida M, Yonetani H</auth
or>
</item>
<item>
<title>Visualization of a small hidden intracranial aneurysm during endova
scular thrombectomy for acute MCA occlusion.</title>
<link>http://europepmc.org/abstract/MED/24920989?source=rss</link>
<description>Spontaneous aneurysmal thrombosis as a cause for acute ischem
ic stroke is a rarely described complication of small unruptured intracranial an
eurysms. We present an interesting case of a stroke in a woman with an occult ac
utely thrombosed middle cerebral artery bifurcation aneurysm that was found duri
ng successful thrombus aspiration of the occluded parent vessel. Although rare,
small aneurysms have to be considered as a possible cause for a thrombotic vesse
l occlusion. Catheters and thrombectomy devices have to be used carefully while
performing mechanical revascularization.</description>
<author>Khn AL, Hou SY, Spilberg G, Wakhloo AK</author>
</item>
<item>
<title>Treatment of symptomatic fusiform aneurysm in basilar artery by ste
nting following coiling technique.</title>
<link>http://europepmc.org/abstract/MED/24535790?source=rss</link>
<description>AIM: The present stent-assisted coil technique has many limit
ations especially in treating fusiform aneurysms. We aimed to introduce stenting
following coiling technique to treat fusiform aneurysms. MATERIAL and METHODS:
From January 2009 to December 2010, we treated 6 patients with fusiform aneurysm
s in basilar artery (BA) by stenting following coiling technique. The 6 patients
included four men and two women (age from 20 to 78 years, mean age 51 years). T
wo patients had subarachnoid hemorrhage, whereas 4 had unruptured aneurysms with
progressive brainstem symptoms. In the procedure of endovascular treatment, the
stent was delivered after coiling to compress the coils against the aneurysm wa
ll and form a lumen in basilar artery. RESULTS: Five patients had an excellent r
ecovery with a satisfactory clinical result with an average 15.4 months follow-u
p. Four patients received follow-up angiographic imaging with an average 13 mont
hs, whereas 3 patients demonstrated complete aneurysm occlusion with reconstruct
ive BA patency. Re-growth occurred in one patient, although clinically stable. N
one had angiographic evidence of in-stent stenosis. CONCLUSION: Stenting followi
ng coiling technique may be a feasible and effective method to reshape parent ar
teries and to embolize fusiform aneurysms safely. However, this technique may be
considered in selected patients.</description>
<author>Wang Y, Yang X, Youxiang L, Shiqing M, Chuhan J, Zhongxue W, Kocer
N</author>
</item>
<item>
<title>Endovascular management of cerebral vasospasm following aneurysm ru
pture: outcomes and predictors in 116 patients.</title>
<link>http://europepmc.org/abstract/MED/24529225?source=rss</link>
<description>OBJECTIVE: To retrospectively assess the safety and efficacy
of endovascular treatment of cerebral vasospasm with different modalities and as
sess predictors of outcome. METHODS: Endovascular treatment was indicated in the
event of neurological deterioration refractory to medical therapy. Data were co
llected for 116 patients treated at our institution. RESULTS: Vasospasm was trea
ted with balloon angioplasty in 52.6%, intra-arterial nicardipine infusion in 19
.8%, or both in 27.6%. Angiographic vasospasm was reversed in all but 4 (96.6%)
patients. The complication rate was 0.9%. Twenty patients (17.2%) had incipient
pre-procedure hypodensities; 3 (15%) hypodensities were reversed and neurologica
l improvement occurred in 60% of these patients. Retreatment was required in 22

(19%) patients. Higher Hunt and Hess grades and treatment with nicardipine alone
predicted retreatment. Neurological improvement was noted in 82%. Male gender,
pre-procedure hypodensities, and posterior communicating artery aneurysm locatio
n negatively predicted neurological recovery. Favorable outcomes were noted in 7
3%. Higher Hunt and Hess grades, pre-procedure hypodensities, posterior circulat
ion aneurysms, and no neurological recovery predicted poor outcome. CONCLUSION:
Endovascular therapy for vasospasm has an excellent safety-efficacy profile. Bal
loon angioplasty and nicardipine are equally effective but effects of nicardipin
e are less durable. Patients with incipient pre-procedure hypodensities benefit
from endovascular intervention and should probably not be excluded from treatmen
t.</description>
<author>Chalouhi N, Tjoumakaris S, Thakkar V, Theofanis T, Hammer C, Hasan
D, Starke RM, Wu C, Gonzalez LF, Rosenwasser R, Jabbour P</author>
</item>
<item>
<title>Patency of the posterior communicating artery after flow diversion
treatment of internal carotid artery aneurysms.</title>
<link>http://europepmc.org/abstract/MED/24731582?source=rss</link>
<description>BACKGROUND AND PURPOSE: Cerebral aneurysm treatment with the
Pipeline Embolization Device (PED) often mandates device placement across the os
tia of arteries of the Circle of Willis. We determined the patency rates of the
posterior communicating artery (Pcomm) after placement across its ostium a PED a
nd studied neurologic outcomes in these patients. METHODS: We analyzed, retrospe
ctively, a consecutive series of patients in whom a PED was placed across the os
tium of Pcomm while treating the target aneurysm. Pcomm arterial flow after PED
placement was graded on a 3-point scale at post-operative angiography and follow
-up angiography. Data on pretreatment aneurysm rupture status, concomitant coili
ng, number of PEDs used, and neurologic status at follow-up were collected. RESU
LTS: Eleven patients with 13 aneurysms were included in this study. All patients
had an ipsilateral posterior cerebral artery arising from the basilar artery (P
1). In the immediate post-procedural setting, four patients (36%) had diminished
Pcomm flow rates. After a mean follow-up of 12.66.7 months, three Pcomm arteries
(27%) were occluded and two Pcomm arteries (18%) had diminished flow. Of patien
ts with diminished flow/occluded Pcomm at follow-up, 80% (4/5) had diminished fl
ow at initial post-procedure angiography compared to none of the six patients wi
thout diminished/occluded flow immediately post treatment. No patients suffered
new neurologic symptoms at follow-up. CONCLUSIONS: Approximately one half of Pco
mm arteries demonstrated occlusion or decreased flow at follow-up if the ostia a
re covered with a flow diversion device. Covering the Pcomm ostium in patients w
ith a P1 did not result in any neurologic deficits.</description>
<author>Brinjikji W, Lanzino G, Cloft HJ, Kallmes DF</author>
</item>
<item>
<title>Three-dimensional MDCT angiography of splanchnic arteries: Pearls a
nd pitfalls.</title>
<link>http://europepmc.org/abstract/MED/24994585?source=rss</link>
<description>Fast scanning along with high resolution of multidetector com
puted tomography (MDCT) have expanded the role of non-invasive imaging of splanc
hnic arteries. Advancements in both MDCT scanner technology and three-dimensiona
l (3D) imaging software provide a unique opportunity for non-invasive investigat
ion of splanchnic arteries. Although standard axial computed tomography (CT) ima
ges allow identification of splanchnic arteries, visualization of small or dista
l branches is often limited. Similarly, a comprehensive assessment of the comple
x anatomy of splanchnic arteries is often beyond the reach of axial images. Howe
ver, the submillimeter collimation that can be achieved with MDCT scanners now a
llows the acquisition of true isotropic data so that a high spatial resolution i
s now maintained in any imaging plane and in 3D mode. This ability to visualize
the complex network of splanchnic arteries using 3D rendering and multiplanar re
construction is of major importance for an optimal analysis in many situations.
The purpose of this review is to discuss and illustrate the role of 3D MDCT angi

ography in the detection and assessment of abnormalities of splanchnic arteries


as well as the limitations of the different reconstruction techniques.</descript
ion>
<author>Dohan A, Dautry R, Guerrache Y, Fargeaudou Y, Boudiaf M, Le Dref O
, Sirol M, Soyer P</author>
</item>
<item>
<title>Idiopathic bilateral segmental pulmonary artery aneurysm.</title>
<link>http://europepmc.org/abstract/MED/24484839?source=rss</link>
<description>Aneurysms of segmental pulmonary arteries are rare. They can
be potentially fatal, but remain undetected in the majority of cases. A young pe
rson reported with massive hemoptysis, and a ruptured large segmental pulmonary
artery aneurysm of the left lung was identified as the cause. Incidentally a sma
ller aneurysm on the segmental artery of the right lung was noticed. The case is
of rare occurrence, and the urgency of intervention on the left lung with consi
deration of an aneurysm on the right lung makes this case challenging. The clini
cal decision making for the choice of procedure for this rare and emergent situa
tion is presented.</description>
<author>Pande S, Tewari P, Agarwal SK, Jain M, Phadke RV</author>
</item>
<item>
<title>Hemifacial spasm and recurrent stroke due to vertebrobasilar dolich
oectasia coexisting with saccular aneurysm of the basilar artery: a case report.
</title>
<link>http://europepmc.org/abstract/MED/23546920?source=rss</link>
<description>We describe a patient presented with sequential events of hem
ifacial spasm, cerebral infarction and fatal subarachnoid hemorrhage. All of the
m are seemingly separate entities. Radiological examination revealed that the ca
use was vertebrobasilar dolichoectasia (VBD) coexisting with a giant saccular an
eurysm of basilar artery. VBD is a dilatation and elongation of vertebral artery
(VA) and basilar artery (BA) which is of different mechanism from saccular aneu
rysm. The condition is very rare and its progression may result in compression o
f brainstem and cranial nerves, ischemic and/or hemorrhagic stroke. The treatmen
t of such condition is difficult and further research on the risk stratification
of VBD for predicting stroke. Close monitoring and aggressive surgical interven
tions might be needed for high-risk patients.</description>
<author>Yuan F, Lin J, Ding L, Chao Y, Wenke L, Heng Z</author>
</item>
<item>
<title>Treatment of 14 intracranial aneurysms with the FRED system.</title
>
<link>http://europepmc.org/abstract/MED/24062251?source=rss</link>
<description>BACKGROUND: Endovascular treatment of intracranial aneurysms
via flow diversion has become increasingly popular over the past several years.
The flow redirection endoluminal device (FRED; Microvention, Tustin, California,
USA) system is a next generation closed cell paired stent flow diversion device
. OBJECTIVE: Our initial clinical experience with the FRED system is described.
We believe this series to be the first use of the FRED system in the western hem
isphere. METHODS: 14 aneurysms were treated utilizing the FRED system in 13 pati
ents. Post-deployment angiography and fluoro CTs were obtained in all cases. RES
ULTS: Immediate post-treatment angiography demonstrated reduced flow into all an
eurysms although no long term angiographic data are yet available. The device pr
oved technically easy to deploy and recapture after partial deployment if needed
. No complications, technical or otherwise, were encountered. Radiographic visib
ility and ability to maintain its internal cylindrical shape in tortuous arterie
s, as demonstrated by fluoro CT, was at least as good as the pipeline embolizati
on device. CONCLUSIONS: The FRED system was technically easy to deploy with no p
rocedural complications occurring in this first reported series of 14 aneurysms.
The ability of the FRED system to be recaptured after partial deployment and to
maintain its internal shape in tortuous vessels was demonstrated well. Long ter

m clinical and angiographic follow-up along with prospective studies are now nee
ded to ascertain the role of the FRED in intracranial aneurysm treatment.</descr
iption>
<author>Diaz O, Gist TL, Manjarez G, Orozco F, Almeida R</author>
</item>
</channel>
</rss>

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