HAAD Poison & Drug Information Center ANTIDOTE CHART

Antidote Black widow spider antiserum Atropine sulfate

Indications Black widow spider envenomations Alpha-2 agonists, antimyesthenic ag
ents, bradyarrhythmia-producing agents, cholinergic agonists, muscarine-containi
ng mushrooms, nerve agents, organophosphate and carbamate insecticides food-born
e botulism, wound, or interstinal colonization in children or adults( not recomm
ended for infant botulism) Medications causing neuroleptic malignant syndrome Le
ad, zinc salts poisoning
Botulinum Antitoxin
Bromocriptine mesylate Calcium disodium EDTA Calcium gluconate gel Calcium gluco
nate INJ
Hydrofluoric acid skin exposure Calcium channel blockers, fluoride salts, hyperk
alemia (not digoxin-induced), hypermagnesemia Cyanide antidote kit Cyanide poiso
ining Cyproheptadine Serotonin syndrome Dantrolene sodium Malignant hyperpyrexia
or muscular rigidity Deferoxamine mesylate Iron poisoning Diazepam Digoxin immu
ne Fab Chloroquine and related antimalarial drugs Cardiac glycoside-containing p
lant ,digitoxin, digoxin Dimercaprol (BAL) Arsenic, copper, gold, lead, lewisite
, mercury Diphenhydramine HCL Drug-induced extrapyramidal symptoms Ethanol Ethyl
ene glycol, methanol Flumazenil Benzodiazepines poisoning Folinic acid Methanol,
methotrexate, trimetrexate, (Leucovorin Calcium) pyrimethamine, trimethoprim Fo
mepizole Ethylene glycol, methanol
Glucagon Beta blockers, calcium channel blockers HAAD-PDIC 2008-2009 Page 1

HAAD Poison & Drug Information Center ANTIDOTE CHART

Insulin (Reglular Insulin) L-Carnitine
Beta blockers, Calcium channel blockers
Valproic acid (hyperammonemia, encephalopathy, liver failure) Methylene blue Met
hemoglobin N-Acetylcysteine Acetaminophen, carbon tetrachloride, other hepatotox
ins Naloxone Opioids,alpha-2 agonists, imidazoline decongestants Octreotide acet
ate Sulfonylurea hypoglycemic agents Phentolamine mesylate Catecholamine extrava
sation, intradigital epinephrine injection Physostigmine Anticholinergic alkaloi
d-containing plants, salicylate antihistamines, atropine and other anticholinerg
ic, intrathecal baclofen Phytonadione (vitamin Coumarin and Indandione derivativ
es, long-acting K1) anticoagulant rodenticides ,warfarin Potassium iodide Preven
ts thyroid uptake of radioactive iodine tablet Pralidoxime chloride Organophosph
ate poisning Protamine sulfate Heparin, Low-Molecular -Weight heparin (LMWH) Pru
ssian blue Radioactive cesium (Cs-137), radioactive thallium (Tl-201), and non-r
adioactive thallium Pyrdoxine Isoniazide, Adjunct to therapy for ethylene glycol
intoxication. Scorpion Anti-serum Scorpion Sting Snake Antivenom Snakes bites S
odium bicarbonate Chlorine gas, Hyperkalemia, Serum Alkalinization, Urine Alkali
nization: Thiamine Ethanol, Ethylene glycol
Expert advice regarding use of antidotes is available from the PDIC Call us at
800 424
Adapted From Olson, KR (Ed): Poisoning & Drug Overdose. 5th Edition. Note: List
is not all-inclusive but reflects agents used more exclusively as antidotes or
antidotal agents used infrequently
HAAD-PDIC 2008-2009
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