Professional Documents
Culture Documents
B)
C)
D)
A)
B)
C)
D)
A)
3.Which of the following diagrams gives the correct identities and arrangement of the structural
subunits in coenzyme A?
A)
B)
C)
D)
a)
pantothenicacid
2aminoethanethiol
phosphorylatedATP
b)
pantothenicacid
2aminoethanethiol
ADP
c)
2aminoethanethiol
pantothenicacid
phosphorylatedATP
d)
2aminoethanethiol
pantothenicacid
ADP
A
B
C
D
4.The missing structural subunit in the following diagram for flavin adenine dinucleotide is
flavin
adenine
A)
B)
C)
D)
phosphate
ribose
phosphate
phosphate.
ribose.
ribitol.
deoxyribose.
Page 1
A)
B)
C)
D)
5.The correct notation for the reduced form of nicotinamide adenine dinucleotide is
NAD+.
NAD.
NADH.
NADH2.
A)
B)
C)
D)
6.Which of the following is a correct skeletal equation for a hydrolysis reaction involving
adenosine phosphates?
ATP ADP + 2Pi
ADP AMP + 2Pi
ATP AMP + PPi
ATP ADP + PPi
A)
B)
C)
D)
A)
B)
C)
D)
A)
B)
C)
D)
9.Which of the following is a correct general description of the reaction that occurs in the
first step of the citric acid cycle?
C2 + C 4 C6
C3 + C 3 C6
C2 + C 2 + C 2 C6
C4 + C 4 C6 + C 2
A)
B)
C)
D)
10.In which two steps of the citric acid cycle are molecules of carbon dioxide produced?
steps 2 and 5
steps 3 and 5
steps 3 and 4
steps 4 and 6
11.How many NADH and FADH2 molecules are produced, respectively, during one turn of
Page 2
A)
B)
C)
D)
A)
B)
C)
D)
A)
B)
C)
D)
13.In which of the following listings of citric acid cycle intermediates are the compounds
listed in order in which they are encountered in a turn of the cycle?
citrate, malate, succinate
alpha-ketoglutarate, succinate, malate
succinyl CoA, malate, isocitrate
oxaloacetate, fumarate, isocitrate
A)
B)
C)
D)
A)
B)
C)
D)
15.The number of membrane-bound protein complexes associated with the electron transport
chain is
one.
two.
three.
four.
A)
B)
C)
D)
Page 3
A)
B)
C)
D)
A)
B)
C)
D)
18.ATP synthesis via oxidative phosphorylation depends on the passage of which of the
following species through membrane-bound ATP synthase?
NADH
FADH2
H+
NAD+
A)
B)
C)
D)
19.How many moles of ATP result from the entry of 5 moles of FADH2 into the electron
transport chain?
5
7.5
10
12.5
A)
B)
C)
D)
20.How many ATP molecules result from the "processing" of 10 acetyl CoA molecule
through the common metabolic pathway?
20
80
100
240
A)
B)
C)
D)
E)
A)
B)
C)
D)
E)
22.Which of the following substances does not contain a B vitamin as a structural subunit?
flavin adenine dinucleotide
nicotinamide adenine dinucleotide
coenzyme A
more than one correct response
no correct response
Page 4
A)
B)
C)
D)
E)
23.Which of the following substances has two unsubstituted ribose molecules as structural
subunits?
FADH2
NAD+
CoA
more than one correct response
no correct response
A)
B)
C)
D)
E)
24.Which of the following substances contains two or more high energy phosphate bonds?
ATP
ADP
AMP
more than one correct response
no correct response
A)
B)
C)
D)
E)
25.Which of the following is a correct letter designation for the reduced form of a
coenzyme?
NAD+
FADH2
NADH2
more than one correct response
no correct response
A)
B)
C)
D)
E)
A)
B)
C)
D)
E)
27.Which of the following citric acid cycle intermediates is decarboxylated during the
operation of the cycle?
oxaloacetate
isocitrate
succinate
more than one correct response
no correct response
Page 5
B)
C)
D)
E)
citrate
malate
more than one correct response
no correct response
A)
B)
C)
D)
E)
29.In which of the following citric acid cycle reactions does the coenzyme FAD participate?
citrate isocitrate
succinate fumarate
malate oxaloacetate
more than one correct response
no correct response
A)
B)
C)
D)
E)
30.Which of the following statements concerning citric acid cycle reactions is correct?
Two secondary alcohol oxidations occur.
Water adds to a carbon-carbon double bond once.
Two phosphorylation reactions occur.
more than one correct response
no correct response
A)
B)
C)
D)
E)
31.Which of the following carry electrons from the citric acid cycle to the electron carriers
of the electron transport chain?
CoA
NAD+
FADH2
more than one correct response
no correct response
A)
B)
C)
D)
E)
32.Which of the following carriers transports electrons from protein complex I to protein
complex III during operation of the electron transport chain?
cyt a3
cyt c1
FMN
more than one correct response
no correct response
A)
B)
C)
D)
33.Which of the following substances is both a reactant and a product in the operation of the
electron transport chain?
O2
FADH2
CoQ
more than one correct response
Page 6
E)
no correct response
A)
B)
C)
D)
E)
34.At which protein complex site in the electron transport chain does proton pumping occur?
protein complex I
protein complex II
protein complex III
more than one correct response
no correct response
A)
B)
C)
D)
E)
A)
B)
C)
D)
36.Statements:
(1) In the last step of the ETC, molecular oxygen is converted to water.
(2) The B vitamin portion of the structure of coenzyme A, which involves riboflavin, is
the reactive site in the molecule.
(3) All of the reactions of the CAC take place in the mitochondrial matrix.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
37.Statements:
(1) FADH2 is the oxidized form of the coenzyme flavin adenine dinucleotide.
(2) All of the electron carriers of the ETC contain iron, and one of them also contains
copper.
(3) One turn of the CAC generates two CO2 molecules, two NADH molecules and two
Page 7
A)
B)
C)
D)
FAD2 molecules.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
A)
B)
C)
D)
38.Statements:
(1) Both ribosomes and mitochondria are examples of organelles.
(2) Cytochromes are heme-containing proteins that can undergo reversible oxidation and
reduction.
(3) The electrons that pass through the various steps of the ETC lose some energy with
each transfer along the chain.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
A)
B)
C)
D)
39.Statements:
(1) In the first step of the CAC, a C2 molecule and a C4 molecule combine to produce a C6
molecule.
(2) ATP, ADP, and AMP differ from each other in the number of adenine subunits present.
(3) The process by which ATP is produced during the operation of the ETC is called
oxidative phosphorylation.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
A)
B)
C)
D)
40.Statements:
(1) High-energy phosphate compounds contain one or more strained bonds which release
above-average amounts of energy when broken.
(2) In the ETC, NADH is oxidized to NAD+.
(3) The fuel for the CAC is acetyl CoA.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
41.Statements:
(1) The CO2 molecules produced in the citric acid cycle are the CO2 molecules we exhale
in the process of respiration.
(2) The oxidized form of nicotinamide adenine dinucleotide is NAD+ and the reduced
Page 8
A)
B)
C)
D)
form in NADH2.
(3) During ETC operation, a buildup of protons occurs on the matrix side of the inner
mitochondrial membrane.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
A)
B)
C)
D)
42.Statements:
(1) Two ribose subunits are present in the coenzyme flavin adenine dinucleotide.
(2) In the common metabolic pathway, 10 molecules of ATP are produced per acetyl CoA
catabolized.
(3) The purpose of step 2 in the CAC is to convert a secondary alcohol to a tertiary
alcohol.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
A)
B)
C)
D)
43.Statements:
(1) Some, but not all, protein complex sites associated with the ETC serve as proton
pumps.
(2) The rate at which the CAC operates is controlled by the body's need for ATP.
(3) Anabolic reactions usually require energy input in order to proceed.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
A)
B)
C)
D)
44.Statements:
(1) Mitochondria contain a multifolded outer membrane and an inner membrane
(2) Two of the electron carriers of the ETC transport change are mobile, moving
between protein complex sites.
(3) The NADH and FAD2 formed during the CAC carry electrons and H+ ions to the ETC.
All three statements are true.
Two of the three statements are true.
Only one of the statements is true.
None of the statements is true.
45.Statements:
(1) Inhibition of the ETC is the mechanism by which cyanide exerts its deadly effect.
(2) Brown fat cells contain the uncoupling agent thermogenin, a protein that creates a
Page 9
A)
B)
C)
D)
Page 10
51.Citrate isocitrate
52.Succinate fumarate
53.Isocitrate -ketoglutarate
54.Malate oxaloacetate
55.Fumarate malate
Use the following to answer questions 56-60:
Characterize each of the citric acid cycle reactions as to type of reaction using the response list.
Responses may be used more than once or need not be used at all.
a) oxidation of a 2 alcohol
b) oxidation with FAD as the oxidizing agent
c) hydration reaction
d) hydrolysis reaction
56.Isocitrate -ketoglutarate
57.Succinate fumarate
58.Succinyl CoA succinate
59.Malate oxaloacetate
60.Fumarate malate
Page 11
66.FADH2
67.NADH
68.CoQ
Page 12
69.cyt c
70.cyt b
Page 13
Answer Key
1.A
2.D
3.C
4.C
5.C
6.C
7.A
8.A
9.A
10.C
11.B
12.C
13.B
14.D
15.C
16.B
17.B
18.C
19.B
20.C
21.A
22.E
23.B
24.A
25.B
26.E
27.B
28.D
29.B
30.D
31.C
32.E
33.C
34.D
35.D
36.C
37.D
38.A
39.B
40.A
41.C
42.C
43.A
44.B
Page 14
45.B
46.b
47.b
48.a
49.b
50.c
51.a
52.d
53.b
54.d
55.d
56.a
57.b
58.d
59.a
60.c
61.b
62.c
63.d
64.b
65.d
66.a
67.a
68.c
69.b
70.a
Page 15