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Title

Summary

Jan 2013
technology
The Future in 50, 100, and 150 Years

We asked leading scientists and science writers to look


forward to what the world will be like in the years 2063, 2113
and 2163 and tell us what role science and technology will
play in our future.

space
Starship Humanity

How future generations will make the voyage from our


earthly home to the planets and beyondand what it means
for our species

quantum physics
Strange and Stringy

Newly discovered states of matter embody what Einstein


called spooky action at a distance. They defy explanation,
but lately answers have come from a seemingly unrelated
corner of physics: string theory

medical engineering
Bionic Connections

A new way to link artificial arms and hands to the nervous


system could allow the brain to control prostheses as
smoothly as if they were natural limbs

life science
Small Wonders

Light microscopy reveals hidden marvels of the natural world

climate
The Coming Megafloods

Huge flows of vapor in the atmosphere, dubbed "atmospheric


rivers," have unleashed massive floods every 200 years, and
climate change could bring more of them

neuroscience
A Confederacy of Senses

Our many different senses collaborate even more than


previously realized. What we hear depends a lot on what we
see and feel

Dec 2012
innovation
World Changing Ideas

10 innovations that are radical enough to alter our lives

physics
The Unquantum Quantum

Quantum theorists often speak of the world as being


pointillist at the smallest scales. Yet a closer look at the laws
of nature suggests that the physical world is actually
continuousmore analog than digital

climate change
The Winters of Our Discontent

Loss of Arctic sea ice is stacking the deck in favor of harsh


winter weather in the U.S. and Europe

medical ethics
Is Drug Research Trustworthy?

The pharmaceutical industry funnels money to prominent


scientists who are doing research that affects its
productsand nobody can stop it

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space
Four Starry Nights

In the driest place on Earth, one astronomer sifts through


starlight to find clues about the Milky Way's evolution. Here
is her account of a typical trip, based on four days in March
2011

art conservation
The Case of the Disappearing
Daguerreotypes

As priceless images from the earliest days of photography


were dissolving in front of museumgoers' eyes, an unlikely
team set out to save them

neuroscience
Mind Theorist

Knowledge of how the brain intuits what someone else is


thinking helps Rebecca Saxe devise possible solutions to
seemingly intractable political and social conflict

Nov 2012
particle physics
The Inner Life of Quarks

What if the smallest bits of matter actually harbor an


undiscovered world of particles?

neuroscience
Grow Your Own Eye

Biologists have coaxed cells to form a retina, a step toward


growing replacement organs outside the body

Loss of ice, melting of permafrost and other climate effects


environment
Global Warming: Faster Than Expected? are occurring at an alarming pace
paleontology
The Strangest Bird

Recent fossil discoveries reveal the surprising evolutionary


history of penguins

science and society


America's Science Problem

The United States faced down authoritarian governments on


the left and right. Now it may be facing an even greater
challenge from within

biology
Autism and the Technical Mind

Children of scientists and engineers may inherit genes that


not only confer intellectual talents but also predispose them
to autism

quantum physics
A New Enlightenment

Quantum theory once seemed like the last nail in the coffin of
pure reason. Now it's looking like its savior

Oct 2012
science
State of The World's Science

A Measure of the Creativity of a Nation is how Well it Works


with those Beyond its Borders

neuroscience
The Language of the Brain

The brain makes sense of our experiences by focusing closely


on the timing of the impulses that flow through billions of
nerve cells

environment
Ecosystems on the Brink

To keep jellyfish, fungi and other creatures from overtaking


healthy habitats, scientists are exploring food webs and
tipping points

physics
The Higgs at Last

After a three-decade search, scientists appear to have found


the elusive particle. Its peculiar properties suggest a new era
in physics could be about to dawn

energy
Kinetic Kite

An airborne wind turbine turns sea breezes into electricity

psychology
The Wisdom of the Psychopaths

We can learn a lot from psychopaths. Certain aspects of their


personalities and intellect are often hallmarks of success

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biochemistry
Journey to the Genetic Interior

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What was once known as junk DNA turns out to hold hidden
treasures, says computational biologist Ewan Birney

Sep 2012
Beyond Limits

How will we transcend today's barriers to get smarter, live


longer, and expand the power of human innovation

evolution
Super Humanity

Our drive to exceed our evolutionary limits sets us apart from


other beasts

intelligence
Can We Keep Getting Smarter?

Ever rising IQ scores suggest that future generations will


make us seem like dimwits in comparison

consciousness
The Case of the Sleeping Slayer

In the neurological netherworld between sleep and


wakefulness, the mind's delirium can turn tragically real

aging
How We All Will Live to Be 100

Two approaches to longevity research aim to extend the


average life span out to a century or more

neuroengineering
Mind in Motion

The idea that paralyzed people might one day control their
limbs just by thinking is no longer a Hollywood-style fantasy

technology
The Edge of Ambition

10 projects that push the boundaries of the engineered world

complexity
Machines of the Infinite

Whether or not machines can quickly answer yes-or-no


questions could affect everything from national security to
the limits of human knowledge

basic science
Questions for the Next Million Years

What would scientists learn if they could run studies that


lasted for hundreds or thousands of yearsor more?

ecology
The Great Climate Experiment

How far can we push the planet?

physics
Beyond the Quantum Horizon

Once viewed as imposing absolute limits on knowledge and


technology, quantum theory is now expanding the power of
computers and the vistas of the mind

Aug 2012
astrophysics
The Benevolence of Black Holes

The matter-eating beast at the center of the Milky Way may


actually account for Earth's existence and habitability

neuroscience
The Joyful Mind

A new understanding of how the brain generates pleasure


could lead to better treatment of addiction and
depressionand even to a new science of happiness

evolutionary biology
New Life for Ancient DNA

Biotechnology reveals how the woolly mammoth survived the


cold and other mysteries of extinct creatures

climate
Lakes on Ice

Scientists are tracking how water atop Greenland's ice sheet


pools and drains. The findings could help predict future rises
in sea level

atomosphere science
Deadly Rays from Clouds

Thunderstorms give out powerful blasts of gamma rays and


x-rays, shooting beams of particlesand even
antimatterinto space. The atmosphere is a stranger place
than we ever imagined

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education
Building a Better Science Teacher

Experience and degrees don't matter in the classroom nearly


so much as mastery of science and math and some plain old
smarts

health
Quiet Little Traitors

Cells that permanently stop dividing have long been


recognized as one of the body's defenses against cancer. Now
they are also seen as a sometime culprit in cancer and a cause
of aging

biodiversity
Which Species will Live?

Like battlefield medics, conservationists are being forced to


explicitly apply triage to determine which creatures to save
and which to let go

bacteriology
Phage Factor

Long ignored by mainstream researchers, the viruses that


infect bacteria have a role to play in modern medicine,
Vincent Fischetti says

Jul 2012
evolution
Why We Help

Far from being a nagging exception to the rule of evolution,


cooperation has been one of its primary architects

space
Reading the Red Planet

At 10:31 p.m. Pacific time on August 5, NASA'S Curiosity


rover will begin the first direct search for habitable
environments on Mars

health
Secrets of the HIV Controllers

A rare group of HIV-positive individuals need no medicine to


keep the virus in check. Their good fortune could point the
way to more powerful treatments--and perhaps a vaccine

engineering
Fleet Foot

Nimble robots like this Cheetah will help the military navigate
terrain too rocky for wheels

polar science
Witness to an Antarctic Meltdown

As glaciers collapse toward the sea, scientists struggle to


figure out how fast the southern continent is melting and what
that means for sea-level rise

physics
Nobel Pursuits

The tools of science have changed since the golden age of


physics, but many of the same questions remain

animal behavior
The Rat that Laughed

Do animals other than humans have a sense of humor?


Maybe so

artificial intelligence
Machines that Think for Themselves

New techniques for teaching computers how to learn are


beating the experts

Jun 2012
medicine
The Ultimate Social Network

Researchers who study the friendly bacteria that live inside


all of us are starting to sort out who is in chargemicrobes or
people?

astrophysics
Super Supernovae

The largest stars die in explosions more powerful than anyone


thought possiblesome triggered in part by the production of
antimatter

neuroscience
The Human Brain Project

Building a vast digital simulation of the brain could transform


neuroscience and medicine and reveal new ways of making
more powerful computers

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technology
Fusion's Missing Pieces

On the road to unlimited energy, the world's most complex


science experiment encounters a few potholes

ecology
Busy Bee

Orchid pollinators are surprisingly promiscuous about the


plants they like

infectious disease
Waiting to Explode

By concocting bird flu viruses that could potentially spread


easily among humans, researchers have ignited a debate
about the need for safety versus open inquiry

history of science
The Right Way to Get It Wrong

Most errors are quickly forgotten. Others end up remaking


the face of science

sociobiology
Life is a Shell Game

Like people, hermit crabs and other animals trade up by


treasuring what others leave behind

virology
Resistance Fighter

Thumbi Ndung'u has moved from Africa to Massachusetts


and back in a quest to halt the AIDS epidemic

May 2012
quantum physics
Loops, Trees and the Search for New
Physics

Maybe unifying the forces of nature isn't quite as hard as


physicists thought it would be

future health
Tomorrow's Medicine

A look at some of the most promising medical devices now in


development

evolution
Triumph of the Titans

The long-necked dinosaurs known as sauropods, once seen as


icons of extinction, thrived for millions of years all around the
world

neuroscience
Erasing Painful Memories

The caustic imprint of a traumatic memory may fade or


vanish with new drug and behavioral therapies

botany
What a Plant Smells

Botanists are getting a whiff of the ways that plants smell one
another. Some plants recognize injured neighbors by scent;
others sniff out a meal

forensic medicine
Telltale Hearts

Despite advances in medical imaging, an autopsy still gives


experts the best picture of what ails us

meteorology
A Better Eye On the Storm

New technology that increases the warning time for


tornadoes and hurricanes could potentially save hundreds of
lives every year

photonics
Nature's Color Tricks

Understanding seven clever tactics animals use to create


dazzling hues may lead to sophisticated new technologies

innovation
Professional Seer

The world's largest computer chipmaker employs a corporate


futurist, Brian David Johnson, to guess what gadgetry and
computing will look like in 2020 and beyond

Apr 2012
human evolution
First of Our Kind

Sensational fossils from South Africa spark debate over how


we came to be human

physics
Quantum Gravity in Flatland

Imagine space were 2-D rather than 3-D. How would the
force of gravity work? The surprising answers are guiding
physicists to a unified theory of nature

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neuroscience
This Is Your Brain in Meltdown

Neural circuits responsible for conscious self-control are


highly vulnerable to even mild stress. When they shut down,
primal impulses go unchecked and mental paralysis sets in

space science
Bound for the Moon

The next rover to roam the moon's surface may come not
from NASA and its rocket scientists but from college students
and private companies working on a shoestring

medicine
Polio's Last Act

As the number of cases of the paralytic disease fall, world


health officials have to grapple with a vexing problem: a
component of the most widely used polio vaccine now causes
more disease than the virus it is supposed to fight

medicine
Birth of a Cold War Vaccine

While the superpowers were busy threatening to destroy each


other with nuclear weapons, Albert B. Sabin turned to a
surprising ally to test his new oral polio vaccinea Soviet
scientist

paleontology
Time Traveler

Artist Charles R. Knight drew on his vast experience


depicting living animals to bring prehistoric creatures to
lifea practice that made him keenly aware of the finality of
extinction

physiology
The Limits of Breath Holding

It's logical to think that the brain's need for oxygen is what
limits how long people can hold their breath. Logical, but not
the whole story

Mar 2012
neuroscience
What Makes Each Brain Unique

How can identical twins grow up with different personalities?


"Jumping genes" move around in neurons and alter the way
they work

astrophysics
The Far, Far Future of Stars

Some say its glory days are long gone, but the universe has
life in it yet. Brand-new types of celestial phenomena will
unfold over the coming billions and trillions of years

paleontology
Dinosaurs of the Lost Continent

The American West once harbored multiple communities of


dinosaurs simultaneouslya revelation that has scientists
scrambling to understand how the land could have supported
so many behemoths

energy
Gather the Wind

If renewable energy is going to take off, we need good ways


of storing it for the times when the sun isn't shining and the
wind isn't blowing

medicine
Blocking HIV's Attack

Scientists have rid one man of HIV by preventing the virus


from entering certain immune cells. But the treatment was
dangerous and likely unrepeatable. Can they figure out a
safer, more broadly achievable way to help millions more?

info tech
The Shadow Web

Governments and corporations have more control over the


Internet than ever. Now digital activists want to build an
alternative network that can never be blocked, filtered or shut
down

biotechnology
Lifting the Black Cloud

Existing antidepressants leave a lot to be desired. They can


take weeks to start working, and they fail many people.
Researchers are scouting for better options

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climate
Hit Them with the Hockey Stick

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Michael E. Mann set out looking for a big scientific problem


and wound up at the center of a political storm over climate
change. Now he tells his side of the story

Feb 2012
physics
Is Space Digital?

An experiment going up outside of Chicago will attempt to


measure the intimate connections among information, matter
and spacetime. If it works, it could rewrite the rules for
21st-century physics

medicine
The Great Prostate Cancer Debate

Evidence shows that screening does more harm than good.


Now what?

environment
Swept From Africa to the Amazon

What the journey of a handful of dust tells us about our


fragile planet

public health
Sleeping With the Enemy

Bed bugs are back. Can science stop them?

citizen science
All Hands on Deck

Volunteers are combing through the logbooks of World War


I-era ships to help researchers fill holes in the earth's climate
record

sustainable agriculture
The Future of Chocolate

Researchers are racing to fortify the embattled cacao tree and


to meet increasing demand for cocoa made from its seeds

brain science
The Collision Syndrome

Football players diagnosed with Lou Gehrig's disease may


suffer from the effect of repeated blows to the head,
controversial new research says

anatomy
Fetal Armor

The placenta does more than nourish offspring in the


wombit actively shapes brain development

bioengineering
The Brittle Star's Apprentice

Chemist Joanna Aizenberg mines the deep sea and the forest
wetlands for nature's design secrets and uses them to fashion
new materials that may change the world

Jan 2012
biology
A New Path to Longevity

Researchers have uncovered an ancient mechanism that


retards aging. Drugs that tweaked it could well postpone
cancer, diabetes and other diseases of old age

cosmology
Goldilocks Black Holes

Tipping the scales at less than about a million suns in mass,


middleweight black holes may hold clues to how their much
larger siblings, and galaxies, first formed

animal behavior
The Compass Within

Animals' magnetic sense is real. Scientists are zeroing in on


how it works

immunology
The Patient Scientist

When Ralph M. Steinman developed pancreatic cancer, he


put his own theories about cancer and the immune system to
the test. They kept him alive longer than expected--but three
days short of learning he had won the Nobel Prize

health
Five Hidden Dangers of Obesity

Excess weight can harm health in ways that may come as a


surprise

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technology
The Department of Pre-Crime

In cities across the U.S. data-rich computer technology is


telling cops where crimes are about to happen. Crime is
down, and the technology is spreading. But does it really
work?

physics
The Science of the Glory

One of the most beautiful phenomena in meteorology has a


surprisingly subtle explanation. Its study also helps to predict
the role that clouds will play in climate change

sustainability
More Food, Less Energy

Changes in agriculture, policy and personal behaviors can


reduce the energy a nation uses to feed itself and the
greenhouse gases it emits

environment
Dust Up

Biologist Jayne Belnap warns of the consequences for the


American West if we don't preserve a home for the minute
organisms that live in desert topsoil

Dec 2011
technology
World Changing Ideas

10 new technologies that will make a difference

technology
The Machine That Would Predict the
Future

If you dropped all the world's data into a black box, could it
become a crystal ball that would let you see the futureeven
test what would happen if you chose A over B? One
researcher thinks so, and he could soon get a billion euros to
build it

space exploration
This Way to Mars

By adapting ideas from robotic planetary exploration, the


human space program could get astronauts to asteroids and
Mars cheaply and quickly

biology
Dazzling Miniatures

Small worlds writ large under the microscope

climate change
After the Deluge

A spate of floods, droughts and heat waves is prompting city


and state leaders to take bold steps to protect their people and
property

neuroscience
Hidden Switches in the Mind

Experience may contribute to mental illness in a surprising


way: by causing "epigenetic" changesones that turn genes
on or off without altering the genes themselves

animal behavior
Ants & the Art of War

Battles among ants can be startlingly similar to human


military operations

forensics
Arm in the Ice

New fingerprint- and DNA-identification techniques solve a


mystery from a 60-year-old plane crash

education
Speaking Out on the "Quiet Crisis"

Strengthening science education is the key to securing our


energy future, says Rensselaer Polytechnic Institute's
president

Nov 2011
archaeology
The 1st Americans

Humans colonized the New World earlier than previously


thoughta revelation that is forcing scientists to rethink
long-standing ideas about these trailblazers

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planetary science
Digging Mars

The Mars Phoenix mission revived hopes that the Red Planet
may be habitable, preparing the way for a new rover to be
launched this month

planetary science
The Smallest Astronauts

Did space rocks seed Earth with life? To test that idea, a
Russian probe is about to see whether microbes can survive a
round-trip to Mars

experimental philosophy
Thought Experiments

Some philosophers today are doing more than thinking


deeply. They are also conducting scientific experiments
relating to the nature of free will and of good and evil

sustainability
Can We Feed the World & Sustain the
Planet?

A five-step global plan could double food production by 2050


while greatly reducing environmental damage

geology
Sleeping Giant

The volcano beneath this calm-looking lake has grown


restive, inspiring a rare collaboration between Chinese and
Korean scientists

biotechnology
The Wipeout Gene

A new breed of genetically modified mosquitoes carries a


gene that cripples its own offspring. They could crush native
mosquito populations and block the spread of disease. And
they are already in the airthough that's been a secret

computing
A Formula for Economic Calamity

Despite the lessons of the 2008 collapse, Wall Street is betting


our future on flimsy science

energy
The Truth About Fracking

Fracturing a deep shale layer one time to release natural gas


might pose little risk to drinking-water supplies, but doing so
repeatedly could be problematic

diagnostics
The Medical Sleuth

As a disease detective at the NIH, William A. Gahl unravels


the cause of illnesses that have stumped other doctors

Oct 2011
astrophysics
The Dark Side of The Milky Way

Dark matter is not just a puzzle. It is a solution

chemistry
Atom Power

2011 is the International Year of Chemistrya well-deserved


celebration of that science's profound power

chemistry
10 Unsolved Mysteries

Many of the most profound scientific questionsand some of


humanity's most urgent problemspertain to the science of
atoms and molecules

chemistry
The Scent of Your Thoughts

Although we are usually unaware of it, we communicate


through chemical signals just as much as birds and bees do

geology
Afghanistan's Buried Riches

Geologists say newfound deposits in the embattled country


could fulfill the world's desire for rare-earth and critical
minerals and end opium's local stranglehold in the process

medicine
A New Ally against Cancer

The FDA recently okayed the first therapeutic cancer


vaccine, and other drugs that enlist the immune system
against tumors are under study

forensics
How Skulls Speak

New 3-D software is helping scientists identify the sex and


ancestral origins of human remains with greater speed and

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precision
physics
Waiting for the Higgs

Even as the last protons spin through the most successful


particle accelerator in history, physicists hope to conjure one
final triumph

paleontology
The Dinosaur Baron of Transylvania

A maverick aristocrat's ideas about dinosaur evolution turn


out to have been decades ahead of their time

biology
Actuary of the Cell

Building on her Nobel Prize-winning research on cell


function, Elizabeth H. Blackburn is trying to find a simple
measure of a person's health risks

Sep 2011
Street-Savvy

Meeting the biggest challenges starts with the city

The Social Nexus

The best way to harness a city's potential for creativity and


innovation is to jack people into the network and get out of
the way

Engines of Innovation

Most of humanity now lives in a metropolis. That simple fact


helps to fuel our continued success as a species

Global Bazaar

Shantytowns, favelas and jhopadpattis turn out to be places


of surprising innovation

Brains Over Buildings

To rejuvenate urban centers, look to teachers and


entrepreneurs

How Green Is My City

Retrofitting is the best way to clean up urban living

All Climate Is Local

Mayors are often better equipped than presidents to cut


greenhouse gases

The Efficient City

Municipalities worldwide are exploiting a host of creative


solutions to reduce energy consumption, water use, waste and
emissions, while also making it easier for people to get around

Castles in the Air

The attacks of 9/11 supposedly ended the age of the


skyscraper. A decade on we're building more than ever

Street Talk

What innovation -- technological or otherwise -- would make


any city a substantially more livable place? We put this
question to urban leaders and our own readers. Here's what
they said

Life in the Meta City

We walk a line between the anarchy of choice and Disneyfication, says the author of Neuromancer

Aug 2011
cosmology
Does the Multiverse Really Exist?

Proof of parallel universes radically different from our own


may still lie beyond the domain of science

human origins
The Evolution of Grandparents

Senior citizens may have been the secret of our species'


success

neuroscience
How To Build a Better Learner

Brain studies suggest new ways to improve reading, writing


and arithmeticand even social skills

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energy
The False Promise of Biofuels

The breakthroughs needed to replace oil with plant-based


fuels are proving difficult to achieve

life science
Treasure in the Trees

Nests offer clues about natural history, climate change and


their owners' mating habits

medicine
A Breath of Fresh Air

Fundamental understanding of basic biology has set the stage


for new treatments for cystic fibrosis

sociology
How New York Beat Crime

With its judicious use of cops and innovative methods, the


Big Apple is a model for how to stem homicides, muggings
and other ills

philosophy of science
Why Math Works

Is math invented or discovered? A leading astrophysicist


suggests that the answer to the millennia-old question is both

archaeology
Zahi Hawass, Egypt's Indiana Jones and
One-Time Mubarak Ally, Tries to Cozy
Up to Pro-Democracy Activists

Egypt had a revolution, but Zahi Hawass, the larger-than-life


minister of antiquities, is still calling his own shots and
making no apologies

Jul 2011
neuroscience
The Limits of Intelligence

The laws of physics may well prevent the human brain from
evolving into an ever more powerful thinking machine

astrophysics
The Periodic Table of the Cosmos

A simple diagram, which celebrates its centennial this year,


continues to serve as the most essential conceptual tool in
stellar astrophysics

health care
The Best Medicine

A quiet revolution in comparative effectiveness research just


might save us from soaring medical costs

climate change
The Last Great Global Warming

Surprising new evidence suggests the pace of the earth's most


abrupt prehistoric warm-up paled in comparison to what we
face today. The episode has lessons for our future

engineering
Underground Railroad

A peek inside New York City's subway line of the future

biology
Evolution of the Eye

Scientists now have a clear vision of how our notoriously


complex eye came to be

cybersecurity
Hacking the Lights Out

Computer viruses have taken out hardened industrial control


systems. The electrical power grid may be next

disease control
Scent of a Human

Decoding how a mosquito sniffs out human targets could lead


to better traps and repellents that cut malaria's spread

cosmology
Bad Boy of Physics

Leonard Susskind rebelled as a teen and never stopped.


Today he insists that reality may forever be beyond reach of
our understanding

Jun 2011
physics
Living In A Quantum World

Quantum mechanics is not just about teeny particles. It


applies to things of all sizes: birds, plants, maybe even people

neuroscience
A Test for Consciousness

How will we know when we've built a sentient computer? By


making it solve a simple puzzle

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nuclear energy
Planning for the Black Swan

The surprising accident at Fukushima puts the spotlight on a


new generation of U.S. nuclear reactors. Are they safe
enough?

biology
A Nobel Celebration

As Nobel Prize winners gather this month to share their


wisdom with younger researchers, Scientific American recalls
some of the articles that Nobel laureates have published in
our pages

technology
Inside the Meat Lab

A handful of scientists aim to satisfy the world's growing


appetite for steak without wrecking the planet. The first step:
grab a petri dish

microbiology
The Smartest Bacteria on Earth

One species of soil microbe makes unusually wise communal


decisions

health
The Devil's Cancer

A contagious tumor threatens to wipe out the famous


Tasmanian devil. Could similarly "catching" cancers arise in
humans, too?

history of science
Greater Glory

In the race to the South Pole, explorer Robert F. Scott refused


to sacrifice his ambitious science agenda

global warming
"I Stick to Science"

Why Richard A. Muller wouldn't tell House climate skeptics


what they wanted to hear

May 2011
sustainability
7 Radical Energy Solutions

The failure rate may be 90 percent, but if any of these exotic


technologies succeeds it could significantly improve energy
security and efficiency

cosmology
The Lost Galaxies

By the latest estimate, the observable universe contains 200


billion galaxies. Astronomers wonder: Why so few?

neuroscience
The Hidden Organ In Our Eyes

Our bodies adjust to the cycle of day and night thanks to


specialized neurons in our eyes. Ongoing study of these cells
could lead to new treatments for winter depression and other
conditions

A forgotten number system invented in the 19th century may


mathematics
provide the simplest explanation for why our universe could
The Strangest Numbers in String Theory
have 10 dimensions
medicine
Fast Track to Vaccines

Analyzing all the layers of the immune system at once speeds


design and may one day deal a decisive blow against HIV

physics
The Space Station's Crown Jewel

A fancy cosmic-ray detector, the Alpha Magnetic


Spectrometer, is about to scan the cosmos for dark matter,
antimatter and more

agriculture
The Growing Menace from Superweeds

Pigweed, ragweed and other monsters have begun to


outsmart the advanced technologies that protect the biggest
U.S. cash crops

natural history
Masters of Disguise

Animal mimicry takes many formsincluding chemical and


acoustic varietiesand offers unique insights into evolution

creativity
Inner Sparks

Hearing specialist and sax player Charles J. Limb says that


studying the brain during flights of improvisation may provide

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new understanding of creativityas well as insight into the


musical genius of John Coltrane
Apr 2011
cosmology
The Inflation Debate

Is the theory at the heart of modern cosmology deeply


flawed?

medicine
The Enemy Within

A new pattern of antibiotic resistance that is spreading


around the globe may soon leave us defenseless against a
frighteningly wide range of dangerous bacterial infections

imaging
Neuroscience in the Courtroom

Brain scans and other types of neurological evidence are


rarely a factor in trials today. Someday, however, they could
transform judicial views of personal credibility and
responsibility

environment
Can the Dead Sea Live?

Irrigation and mining are sucking the salt lake dry, but
together Israel, Jordan and the Palestinian Authority could
save the sacred sea

artificial intelligence
Solving the Cocktail Party Problem

Computers have great trouble deciphering voices that are


speaking simultaneously. That may soon change

cell biology
The Orderly Chaos of Proteins

To do their magic in the cell, proteins must fold into rigid


shapesor so standard wisdom says. But a more tangled
story is beginning to emerge

seismology
Seconds Before the Big One

Earthquake detection systems can sound the alarm in the


moments before a big tremor strikestime enough to save
lives

sustainability
Food Fight

Genetically modified crops, says agro-research czar Roger


Beachy, receive an unjustified shellacking from
environmentalists

animal behavior
Natural-Born Killer

Lethal from day one, the tentacled snake uses surprisingly sly
tactics to capture fish

Mar 2011
psychology
The Neuroscience of True Grit

When tragedy strikes, most of us ultimately rebound


surprisingly well. Where does such resilience come from?

space science
Journey to the Innermost Planet

Mercury has never been orbited by a spacecraft before. That


will change this month

medicine
Diseases in a Dish

A creative use of stem cells made from adult tissues may


hasten drug development for debilitating diseases

imaging
Signals in a Storm

A new computer imaging technique shows researchers how


brain cells communicateone molecule at a time

archaeology
Putting Stonehenge in Its Place

An increasingly accepted view holds that the great stone


circle may have been just part of a much larger ceremonial
landscape

physics
Demons and the Quest Entropy for
Absolute Zero

A 19th-century thought experiment has turned into a real


technique for reaching ultralow temperatures, paving the way
to new scientific discoveries as well as to useful applications

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climate change
A Shifting Band of Rain

By mapping equatorial rainfall since A.D. 800, scientists have


figured out how tropical weather may change through 2100

public health
Not Just an Illness of the Rich

Recent global health campaigns have focused on HIV,


tuberculosis and malaria. Tackling the growing threat from
cancer, says medical anthropologist Paul Farmer, could
improve health care more broadly

paleontology
Dinosaur Death Trap

On a trip to the Gobi Desert, a team of fossil hunters unearths


a death scene that reveals new clues about how dinosaurs
lived

Feb 2011
health
How to Fix the Obesity Crisis

Although science has revealed a lot about metabolic


processes that influence our weight, the key to success may
lie elsewhere

space
Citizen Satellites

Tiny, standardized spacecraft are making orbital experiments


affordable to even the smallest research groups

sustainability
The Blue Food Revolution

New fish farms out at sea, and cleaner operations along the
shore, could provide the world with a rich supply of much
needed protein

cognitive psychology
How Language Shapes Thought

The languages we speak affect our perceptions of the world

biology
The Inner Life of the Genome

The way our genes are arrayed and move in the 3-D space of
the cell nucleus turns out to profoundly influence how they
function, in both health and disease

ecology
A Friend to Aliens

Buckthorn, garlic mustard and many other invasive species


do not pose as big a threat as some scientists think, says
ecologist Mark Davis

astrophysics
X-Ray Vision

Thanks to amazing nested mirrors, NASA's NuSTAR


telescope is set to reveal hidden phenomena in the cosmos

neuroprosthetics
Mind Out of Body

In an exclusive excerpt from his new book, a pioneering


neuroscientist argues that brain-wave control of machines will
allow the paralyzed to walk and portends a future of mind
melds and thought downloads

history of science
Jefferson's Moose

Thomas Jefferson waged a second revolution, fighting the


image created by European naturalists of a degenerate
America

Jan 2011
evolution
Dawn of the Deed

Fish fossils push back the origin of copulation in backboned


animals and suggest that it was a key turning point in our
evolution

space
Contact The Day After

If we are ever going to pick up a signal from E.T., it is going


to happen soon, astronomers say. And we already have a
good idea how events will play out

infectious disease
Flu Factories

The next pandemic virus may be circulating on U.S. pig


farms, but health officials are struggling to see past the front

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gate
energy
In Search of the Radical Solution

The greatest energy payoffs, says investor Vinod Khosla, will


come from fundamentally reinventing mainstream
technologies

ecology
Seeds of the Amazon

Botanists have collected seeds from one of the most


biologically diverse places on earth

neuroscience
100 Trillion Connections

The noise of billions of brain cells trying to communicate with


one another may hold a crucial clue to understanding
consciousness

environment
Casualties of Climate Change

Shifts in rainfall patterns and shorelines will contribute to


mass migrations on a scale never before seen

computer science
Rise of the Robo Scientists

Machines can devise a hypothesis, carry out experiments to


test it and assess resultswithout human intervention

public health
Radioactive Smoke

The tobacco industry has known for decades how to remove


a dangerous isotope from cigarettes but has done nothing
about it. The government now has the power to force a
change

Dec 2010
innovation
World Changing Ideas

Ten thoughts, trends and technologies that have the power to


transform our lives

physics
A Geometric Theory of Everything

Deep down, the particles and forces of the universe are a


manifestation of exquisite geometry

paleontology
Blood from Stone

Mounting evidence from dinosaur bones shows that, contrary


to common belief, organic materials can sometimes survive in
fossils for millions of years

biology
Life Unseen

Microscopic landscapes show a surprising diversity of forms

health
Hallucinogens as Medicine

In a matter of hours, mind-altering substances may induce


profound psychological realignments that can take decades to
achieve on a therapist's couch

info science
Long Live the Web

The Web is critical not merely to the digital revolution but to


our continued prosperityand even our liberty. Like
democracy itself, it needs defending

life science
Jane of the Jungle

Primatologist Jane Goodall shares insights from her 50 years


among chimpanzees

space exploration
Jump-Starting the Orbital Economy

Why NASA's plan to get out of the manned spaceflight


business may (finally) make space travel routine

robotics
Cyborg Beetles

Tiny flying robots that are part machine and part insect may
one day save lives in wars and disasters

Nov 2010
cosmology
Dark Worlds

A shadow cosmos, woven silently into our own, may have its
own rich inner life

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neuroscience
Controlling the Brain with Light

With a technique called optogenetics, researchers can probe


how the nervous system works in unprecedented detail. Their
findings could lead to better treatments for psychiatric
problems

engineering
How to Build the Supergrid

The U.S. needs a new electric transmission system to deliver


cleaner, more reliable power nationwide. Four steps could
clear hurdles

ecology
Phosphorus Lake

Strip-mining Florida to fertilize the nation

physics
Dr. Unification

For years the cosmos and the atom have been at odds with
one another. If any physicist can reconcile them, it's Steven
Weinberg

A new malaria vaccine, a plan to immunize mosquitoes and


medicine
other "crazy" ideas have brightened prospects for
Halting the World's Most Lethal Parasite
vanquishing this killer
technology
From Silk Cocoon to Medical Miracle

Scientists are crafting arteries, ligaments, circuitry and


holograms from worm yarn

environment
Climate Heretic

Why can't we have a civil conversation about climate?

Oct 2010
evolution
How We Are Evolving

New analyses suggest that recent human evolution has


followed a different course than biologists would have
expected

astronomy
Origami Observatory

NASA is building an innovative and risky space telescope


that promises to surpass the hugely successful Hubble. Here's
an exclusive, behind-the-scenes look at the most audacious
space project in decades

poll
In Science We Trust

Our Web survey of readers suggests that the scientifically


literate public still trusts its expertswith some important
caveats

medicine
Revolution Postponed

The Human Genome Project has failed so far to produce the


medical miracles that scientists promised. Biologists are now
divided over what, if anything, went wrongand what needs
to happen next

physics
The (Elusive) Theory of Everything

Physicists have long sought to find one final theory that


would unify all of physics. Instead they may have to settle for
several

robotics
Robot Be Good

Autonomous machines will soon play a big role in our lives.


It's time they learned how to behave ethically

biology
Sensational Sucker

The octopus sucker can feel, taste, grip, manipulateand act


of its own accord

mind
Desperate for an Autism Cure

Diagnoses have soared, but valid treatments are few. Parents


have turned instead to dubious, and often risky, alternative
therapies

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energy
Reinventing the Leaf

The ultimate fuel may come not from corn or algae but
directly from the sun itself

info science
Digitizer in Chief

The first step toward transparent government, says White


House information czar Vivek Kundra, is to make all its
information freely available on the Web

Sep 2010
Eternal Fascinations with the End

Why we're suckers for stories of our own demise

medicine
Why Can't We Live Forever

As we grow old, our own cells begin to betray us. By


unraveling the mysteries of aging, scientists may be able to
make our lives longer and healthier

bioethics
When Does Life Belong to the Living?

With thousands of people on the waiting lists for organs,


doctors are bending the rules about when to declare that a
donor is dead. Is it ethical to take one life and give it to
another?

forensics
Dust to Dust

The brief, eventful afterlife of a human corpse

anthropology
Last of Their Kind

The world's cultures have been disappearing, taking valuable


knowledge with them, but there is reason to hope

technology
Good Riddance

A highly selective list of human creations the world would be


better off without

environment
How Much is Left?

A graphical accounting of the limits to what one planet can


provide

risk analysis
Laying Odds on the Apocalypse

Could modern civilization really come to an end? Experts


take stock of eight doomsday scenarios

cosmology
Could Time End?

Yes. And no. For time to end seems both impossible and
inevitable. Recent work in physics suggests a resolution to the
paradox

trends
What Comes Next

The flip side to every ending is a new beginning. We asked


the visionary scientists on our advisory board what new
trends will shape the decades to come

Aug 2010
space
Planets We Could Call Home

The night skies are littered with distant planets, but what are
they really like? Theoretical models suggest that a surprising
number of "exoplanets" could be similar to Earthand may
even support life

special
Origins

Sometimes we forget where a story really starts. Are electric


cars new? Were did malaria start? Who invented spaghetti?
Read on, for the surprising origins of many strange and
familiar things.

anthropology
When the Sea Saved Humanity

Shortly after Homo sapiens arose, harsh climate conditions


nearly extinguished our species. Recent finds suggest that the
small population that gave rise to all humans alive today
survived by exploiting a unique combination of resources
along the southern coast of Africa

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medicine
Robot Pills

A voyage through the human body is no longer mere fantasy.


Tiny devices may soon perform surgery, administer drugs and
help diagnose disease

environment
Threatening Ocean Life from the Inside
Out

Carbon dioxide emissions are making the oceans more acidic,


imperiling the growth and reproduction of species from
plankton to squid

imaging
Filming the Invisible in 4D

Picture this: a movie revealing the inner workings of a cell or


showing a nanomachine in action. A new microscopy is
making such imaging possible

technology
The Hacker in Your Hardware

As if software viruses weren't bad enough, the microchips


that power every aspect of our digital world are vulnerable to
tampering in the factory. The consequences could be dire

environment
Plastic Surf

Small remnants of toys, bottles and packaging have an


unhealthful afterlife in the ocean

Jul 2010
cosmology
Is The Universe Leaking Energy?

Total energy must be conserved. Every student of physics


learns this fundamental law. The trouble is, it does not apply
to the universe as a whole

medicine
DNA Drugs Come of Age

After years of false starts, a new generation of DNA vaccines


and medicines for HIV, influenza and other stubborn illnesses
is now in clinical trials

transportation
The Dirty Truth About Plug-In Hybrids

How green is that electric car? Depends on where you plug it


in

robotics
War of the Machines

Robots on and above the battlefield are bringing about the


most profound transformation of warfare since the advent of
the atom bomb

energy
Clean Energy From Filthy Water

California cities are pumping their treated wastewater


underground to create electricity

evolution
Winged Victory

Modern birds, long thought to have arisen only after the


dinosaurs perished, turn out to have lived alongside them

psychology
How Babies Think

Even the youngest children know, experience and learn far


more than scientists ever thought possible

environment
The Drillers Are Coming

Companies and regulators are squaring off over a


controversial technique that yields natural gas but threatens
to pollute water supplies

Jun 2010
Several events, both natural and man-made, can happen
suddenly and at any time, completely transforming societies.
future
12 Events That Will Change Everything Many of these events will not unfold the way popular
conceptions have imagined they will.
medicine
Alzheimer's - Forestalling the Darkness

Interventions before symptoms appear could be key to


slowing or stopping the leading cause of dementia

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physics
Is Time An Illusion?

The concepts of time and change may emerge from a


universe that, at root, is utterly static

environment
Washing Carbon Out of the Air

Machines could absorb carbon dioxide from the atmosphere,


slowing or even reversing its rise and reducing global
warming

archaeology
Did Neandertals Think Like Us?

Joo Zilho defends his controversial view that our


oft-maligned relatives shared our cognitive abilities

earth science
The Earth's Missing Ingredient

The discovery of a novel high-density mineral means that the


earth's mantle is a more restless place than scientists
suspectedand offers new clues to the planet's history

security
Fake Botox, Real Threat

A booming market for a counterfeit beauty product could put


a deadly biological weapons agent in the wrong hands

May 2010
astrophysics
Through Neutrino Eyes

Neutrinos are no longer just a curiosity of physics but a


practical tool for astronomy

medicine
Your Inner Healers

Reprogramming cells from your own body could give them


the therapeutic power of embryonic stem cells, without the
political controversy

transportation
Revolutionary Rail

High-speed trains are coming to the U.S.

neuroscience
Uncanny Sight in the Blind

Some people who are blind because of brain damage have


"blindsight": an extraordinary ability to react to emotions on
faces and even navigate around obstacles without knowing
they can see anything

climate change
Arctic Plants Feel the Heat

Global warming is dramatically revamping not only the ice


but also tundra and forests at the top of the world, greening
some parts and browning others. The alterations could
exacerbate climate change

innovations
A Better Lens on Disease

Computerized pathology slides may help doctors make faster


and more accurate diagnoses

food science
Breeding Cassava to Feed the Poor

The world's third-largest source of calories has the potential


to become a more productive and more nutritious crop,
alleviating malnutrition in much of the developing world

Apr 2010

astronomy
8 Wonders of the Solar System

Artist Ron Miller takes us on a journey to eight of the most


breathtaking views that await intrepid explorers of our solar
system. The scale of these natural wonders dwarfs anything
Earth has to offer. What might we see and feel if we could
travel to these distant domains? The artist's eyeinterpreting
data from probes such as NASA's Cassini, which is now
exploring the Saturnian system, and MESSENGER, which
has flown by Mercury three times and goes into permanent
orbit next Marchallows us an early visit to these
unforgettable locales.

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neuroscience
Faulty Circuits

Neuroscience is revealing the malfunctioning connections


underlying psychological disorders and forcing psychiatrists
to rethink the causes of mental illness

sustainability
Boundaries for a Healthy Planet

Humankind has fundamentally altered the planet. But new


thinking and new actions can prevent us from destroying
ourselves. Scientists have set thresholds for key
environmental processes that, if crossed, could threaten
Earth's habitability

sustainability
Solutions to Environmental Threats

Ominously, three thresholds for key environmental processes


have already been exceeded. Experts tell Scientific American
which actions will keep key processes in bounds

sustainability
Breaking the Growth Habit

Society can safeguard its future only by switching from


reckless economic growth to smart maintenance of wealth
and resources

medicine
Regaining Balance with Bionic Ears

Electronic implants in the inner ear may one day restore clear
vision and equilibrium in some patients who experience
disabling unsteadiness

technology
The Rise of Instant Wireless Networks

Wireless networks that do not depend on a fixed


infrastructure will allow for ubiquitous connectivity
regardless of the situation

biology
The Hidden Life of Truffles

Not just for gourmands, truffles play essential roles in the


health of ecosystems

Mar 2010
planetary science
The Moon That Would Be A Planet

Titan, Saturn's largest natural satellite, scarcely deserves to be


a called a mere moon. It has an atmosphere thicker than
Earth's and a surface that is almost as varied

neuroscience
The Brain's Dark Energy

Brain regions active when our minds wander may hold a key
to understanding neurological disorders and even
consciousness itself

energy
Fusion's False Dawn

Scientists have long dreamed of harnessing nuclear


fusionthe power plant of the starsfor a safe, clean and
virtually unlimited energy supply. Even as a historic milestone
nears, skeptics question whether a working reactor will ever
be possible

geology
Evolution of Minerals

Looking at the mineral kingdom through the lens of deep time


leads to a startling conclusion: most mineral species owe their
existence to life

medicine
Toxic Gas, Lifesaver

Hydrogen sulfide, a lethal gas best known for smelling like


rotten eggs, turns out to play key roles in the bodya finding
that could lead to new treatments for heart attack victims and
others

animal behavior
Worm Charmers

As Charles Darwin had suspected, earthworms that flee from


ground vibrations do so to escape hungry moleseven
though sometimes it is humans chasing them

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environment
Climate Change: A Controlled
Experiment

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Scientists have carefully manipulated grasslands and forests


to see how precipitation, carbon dioxide and temperature
changes affect the biosphere, allowing them to forecast the
future

Feb 2010
astronomy
Cloudy with a Chance of Stars

Making a star is no easy thing

evolution
The Naked Truth

Recent findings lay bare the origins of human


hairlessnessand hint that naked skin was a key factor in the
emergence of other human traits

transportation
Better Mileage Now

Emerging technologies could make the internal-combustion


engine substantially more fuel-efficient, even as green
vehicles make inroads

medicine
The Art of Bacterial Warfare

New research reveals how bacteria hijack our body's cells


and outwit our immune systemand how we can use their
own weapons against them

environment
Fixing the Global Nitrogen Problem

Humanity depends on nitrogen to fertilize croplands, but


growing global use is damaging the environment and
threatening human health. How can we chart a more
sustainable path?

perception
Seeing Forbidden Colors

People can be made to see reddish green and yellowish


bluecolors forbidden by theories of color perception. These
and other hallucinations provide a window into the
phenomenon of visual opponency

life science
The Prolific Afterlife of Whales

On the deep seafloor, the carcasses of the largest mammals


give life to unique ecosystems

Ask the Experts

Can people ever lose their fingerprints?

Jan 2010
cosmology
Looking for Life in the Multiverse

Universes with different physical laws might still be habitable

biology
The Rise and Fall of Nanobacteria

Once believed to be the smallest pathogens known,


nanobacteria have now proved to be something almost as
strange. They do play a role in healthjust not the one
originally thought

earth science
Violent Origins of Continents

Did asteroid strikes during the earth's youth spawn the


earliest fragments of today's landmasses?

info tech
Real Money from Virtual Worlds

Online fantasy games enable developing world entrepreneurs


to make a living by trading stashes of make-believe gold for
hard cash

environment
Local Nuclear War, Global Suffering

Worry has focused on the U.S. versus Russia, but a regional


nuclear war between India and Pakistan could blot out the
sun, starving much of the human race

computers
The Next 20 Years of Microchips

Designers are pushing all the boundaries to make integrated


circuits smaller, faster and cheaper

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medicine
A Plan to Defeat Neglected Tropical
Diseases

http://www.davelo.net/sciam/regular-index.html

The poorest people are not only poor. They are also
chronically sick, making it harder for them to escape poverty.
A new global initiative may break the vicious cycle

Dec 2009
astronomy
Portrait of a Black Hole

By adapting a global network of telescopes, astronomers will


soon get their first look ever at the dark silhouette of a black
hole

innovation
World Changing Ideas

20 ways to build a cleaner, healthier, smarter world

origin of life
Expanding the Limits of Life

Analyses of a recently discovered type of hot vent ecosystem


in the seafloor suggest new possibilities for how life evolved

environment
Methane: A Menace Surfaces

Arctic permafrost is already thawing, creating lakes that emit


methane. The heat-trapping gas could dramatically accelerate
global warming. How big is the threat? What can be done?

archaeology
Decoding an Ancient Computer

New explorations have revealed how the antikythera


mechanism modeled lunar motion and predicted eclipses,
among other sophisticated tricks

medicine
The Double Life of ATP

The molecule ATP, famous as an essential energy source


inside cells, also carries critical messages between cells. That
dual role is suggesting fresh ideas for fighting human diseases

microscopy
Illuminating the Lilliputian

A gallery of images captured by light microscopy reveals the


high art of the natural world

Ask the Experts

Why did NASA decide to launch space shuttles from


weather-beaten Florida?

Nov 2009
astronomy
The Long Lost Siblings of the Sun

The sun was born in a family of stars. What became of them?

neuroscience
New Culprits in Chronic Pain

Glia are nervous system caretakers whose nurturing can go


too far. Taming them holds promise for alleviating pain that
current medications cannot ease

energy
A Path to Sustainable Energy by 2030

Wind, water and solar technologies can provide 100 percent


of the world's energy, eliminating all fossil fuels. Here's how

human evolution
Rethinking the Hobbits of Indonesia

New analyses reveal the mini human species to be even


stranger than previously thought and hint that major tenets of
human evolution need revision

info tech
The Everything TV

Modern insights into the immune system have revived


interest in adding ingredients that can supercharge old
vaccines and make entirely new ones possible

sustainability
The Rise of Vertical Farms

Growing crops in city skyscrapers would use less water and


fossil fuel than outdoor farming, eliminate agricultural runoff
and provide fresh food

auto tech
The Future of Cars

Industry Leaders Look Way Down the Road

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How Does the Coast Guard Find People Lost at Sea?

Oct 2009
astrophysics
Black Stars, Not Holes

Quantum effects may prevent true black holes from forming


and give rise instead to dense entities called black stars

neuroscience
Turbocharging the Brain

Will a pill at breakfast improve concentration and


memoryand will it do so without long-term detriment to
your health?

energy
Squeezing More Oil from the Ground

Amid warnings of a possible "peak oil," advanced


technologies offer ways to extract every last possible drop

archaeology
Lost Cities of the Amazon

The Amazon tropical forest is not as wild as it looks

medicine
Boosting Vaccine Power

Modern insights into the immune system have revived


interest in adding ingredients that can supercharge old
vaccines and make entirely new ones possible

security
Privacy and the Quantum Internet

Courtesy of some of the weirdest laws of physics, we may


someday be able to search and surf the Web without anyone
collecting our data

industry
Biotech's Plans to Sustain Agriculture

Popular movements may call for more organic methods, but


the agricultural industry sees biotechnology as a crucial part
of farming's future

Ask the Experts

Why do whales beach themselves

Sep 2009
cosmology
Origin of the Universe

Cosmologists are closing in on the ultimate processes that


created and shaped the universe

neuroscience
Origin of the Mind

The first step in figuring out how the human mind arose is
determining what distinguishes our mental processes from
those of other creatures

biology
Origin of Life on Earth

Fresh clues hint at how the first living organisms arose from
inanimate matter

info tech
Origin of Computing

The information age began with the realization that machines


could emulate the power of minds

innovations, history
Origins - The Start of Everything

Where do rainbows come from? What about flying cars, love


and LSD?

Aug 2009
human evolution
Twilight of the Neandertals

Paleoanthropologists know more about Neandertals than any


other extinct human. But their demise remains a mystery, one
that gets curiouser and curiouser

physics
Adventures in Curved Spacetime

The possibility of "swimming" and "gliding" in curved, empty


space shows that, even after nine decades, Einstein's theory
of general relativity continues to amaze

energy policy
What Now for Nuclear Waste?

Yucca Mountain was supposed to be the answer to the U.S.'s


nuclear waste problem, but after 22 years and $9 billion, that

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vision is dead. Now some say that doing nothing in the near
term may be the smartest solution
medicine
Surprises from Celiac Disease

Study of a potentially fatal food-triggered disease has


uncovered a process that may contribute to many
autoimmune disorders

electronics
An Iron Key to High-Temperature
Superconductivity?

The discovery that compounds known as iron pnictides can


superconduct at 50 degrees above absolute zero has reignited
physicists' quest for better high-temperature superconductors
and may offer clues to unlocking a 20-year mystery

innovations, medicine
A New Kind of Drug Target

An emerging class of medicines works its magic by targeting


unusual sites on biological molecules

Ask the Experts

How does bathwater well below the boiling point give off
steam?

Jul 2009
space exploration
From the Moon to Mars

The only scientist and field geologist ever to visit the moon
offers some pointers to those who will one day visit Mars

medicine
New Ways to Squash Superbugs

Scientists are using new tools and tactics in the race to


discover novel antibiotics

biofuels
Grassoline at the Pump

Scientists are turning agricultural leftovers, wood and


fast-growing grasses into a huge variety of biofuelseven jet
fuel. But before these next-generation biofuels go
mainstream, they have to compete with oil at $60 a barrel

neuroscience
Origins of the Left & Right Brain

The division of labor by the two cerebral hemispheresonce


thought to be uniquely humanpredates us by half a billion
years. Speech, right-handedness, facial recognition and the
processing of spatial relations can be traced to brain
asymmetries in early vertebrates

conservation
The Ivory Trail

The illegal slaughter of African elephants for ivory is now


worse than it was at its peak in the 1980s. New forensic tools
based on DNA analysis can help stop the cartels behind this
bloody trade

economics
The Science of Bubbles & Busts

The worst economic crisis since the Great Depression has


prompted a reassessment of how financial markets work and
how people make decisions about money

Ask the Experts

Why haven't humans evolved eyes in the back of the head?;


Instead of sequestering carbon dioxide to reduce its effects on
global climate, why don't we split it into harmless carbon and
oxygen?

Jun 2009
astronomy
Improbable Planets

Astronomers are finding planets where there were not


supposed to be any

medicine
The Price of Silent Mutations

Small changes to DNA that were once considered innocuous


enough to be ignored are proving to be important in human
diseases, evolution and biotechnology

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sustainability
Phosphorus: A Looming Crisis

This underappreciated resourcea key part of fertilizersis


still decades from running out. But we must act now to
conserve it, or future agriculture will collapse

tech leaders
Scientific American 10

Certain researchers, politicians, business executives and


philanthropists have recently demonstrated outstanding
commitment to making sure that the benefits of new
technologies and knowledge will accrue to humanity

evolution
The Taming of the Cat

Genetic and archaeological findings hint that wildcats became


house cats earlier--and in a different place--than previously
thought

info tech
Data in the Fast Lanes of Racetrack
Memory

A device that slides magnetic bits back and forth along


nanowire "racetracks" could pack data in a three-dimensional
microchip and may replace nearly all forms of conventional
data storage

Ask the Experts

What causes albinism? Are there any treatments for it?; Why
do two things I like to eat sometimes taste so bad when eaten
together?

May 2009
planetary science
The Planetary Air Leak

As Earth's atmosphere slowly trickles away into space, will


our planet come to look like Venus?

evolution
What Makes Us Human?

Comparisons of the genomes of humans and chimpanzees are


revealing those rare stretches of DNA that are ours alone

environment
Could Food Shortages Bring Down
Civilization?

The biggest threat to global stability is the potential for food


crises in poor countries to cause government collapse. Those
crises are brought on by ever worsening environmental
degradation

security
How to Steal Secrets

Information thieves can now do an end run around


encryption, networks and the operating system

biotech
Progress in Tissue

Pioneers in building living tissue report important advances


over the past decade

nanotech
Powering Nanorobots

Catalytic engines enable tiny swimmers to harness fuel from


their environment and overcome the weird physics of the
microscopic world

Ask the Experts

How does food irradiation work? Is it safe? Indoor plants tend


to grow toward the light, so why do trees outdoors grow
straight instead of leaning toward the equator?

Apr 2009
life science
Saving the Honeybee

The mysterious ailment called colony collapse disorder has


wiped out large numbers of the bees that pollinate a third of
our crops. The causes turn out to be surprisingly complex, but
solutions are emerging

cosmology
Does Dark Energy Really Exist?

Maybe not. The observations that led astronomers to deduce


its existence could have another explanation: that our galaxy
lies at the center of a giant cosmic void

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evolution
The Evolution of Primate Color Vision

Analyses of primate visual pigments show that our color


vision evolved in an unusual way and that the brain is more
adaptable than generally thought

psychology
The Post-Traumatic Stress Trap

A growing number of experts insist that the concept of


post-traumatic stress disorder is itself disordered and that
soldiers are suffering as a result

materials science
The Dawn of the Miniature Green
Lasers

Semiconductors can generate laser light in all colors except


one. But new techniques for growing laser diodes could soon
make brilliant full-spectrum displays a reality

public health
Preventing the Next Pandemic

An international network for monitoring the flow of viruses


from animals to humans might help scientists head off global
epidemics

Ask the Experts

If galaxies are all moving apart at ever increasing speed, how


can they collide? If normal body temperature is about 98
degrees Fahrenheit, why do we feel hot at that air
temperature?

Mar 2009
physics
A Quantum Threat to Special Relativity

Entanglement, like many quantum effects, violates some of


our deepest intuitions about the world. It may also undermine
Einsteins special theory of relativity

nanotech
The World's Smallest Radio

A single carbon nanotube can function as a radio that detects


and plays songs

neuroscience
Saving New Brain Cells

Fresh neurons arise in the adult brain every day. New


research suggests that the cells ultimately help with learning
complex tasksand the more they are challenged, the more
they flourish

energy
The Power of Renewables

The need to tackle global climate change and energy security


makes developing alternatives to fossil fuels crucial.

medicine
New Tactics Against Tuberculosis

The pandemic is growing in many places, and strains resistant


to all existing drugs are emerging. To fight back, biologists are
applying a host of cutting-edge drug development strategies

security
Monitoring for Nuclear Explosions

Detecting a test of a nuclear weapon has become so effective


and reliable that no nation could expect to get away with
secretly exploding a device having military significance

Insights: Escape from the Killing Fields

As the world warms up, some species cannot move to cooler


climes in time to survive. Camille Parmesan thinks humans
should helpeven if it means creating invasive species

Ask the Experts

How do spacecraft orient themselves in the absence of


magnetic poles? Is there any truth to the system they use on
Star Trek?; How long will global uranium deposits fuel the
worlds nuclear reactors at present consumption rates?

Feb 2009
physics
Naked Singularities

The black hole has a troublesome sibling, the naked


singularity. Physicists have long thought--hoped--it could
never exist. But could it?

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medicine, nanotech
Nanomedicine Targets Cancer

Viewing each human body as a system of interacting


molecular networks and targeting disruptions in the system
with nanoscale technologies can transform how disease is
understood, attacked and possibly prevented

earth science
The Origin of the Land Under the Sea

The deep basins under the oceans are carpeted with lava that
spewed from submarine volcanoes and solidified. Scientists
have solved the mystery of how, precisely, all that lava
reaches the seafloor

space science
New Dawn for Electric Rockets

Efficient electric plasma engines are propelling the next


generation of space probes to the outer solar system

neuroscience
Sculpting the Brain

New studies are revealing how the brains convolutions take


shapefindings that could aid the diagnosis and treatment of
autism, schizophrenia and other mental disorders

climate change
The Greenhouse Hamburger

Producing beef for the table has a surprising environmental


cost: it releases prodigious amounts of heat-trapping
greenhouse gases

Insights: Chaos and the Catch of the


Day

There are fewer fish in the sea than ever. Complexity theory,
argues mathematician George Sugihara, provides a
counterintuitive way to revitalize the worlds fisheries

Working Knowledge: Smart Phones

Touch Screens Redefine the Market

Ask the Experts

Why do wind turbines have three narrow blades, whereas my


fan at home has five wide blades?; What happens to the
donors DNA in a blood transfusion?

Jan 2009
evolution
Darwin's Living Legacy

A Victorian amateur undertook a lifetime pursuit of slow,


meticulous observation and thought about the natural world,
producing a theory 150 years ago that still drives the
contemporary scientific agenda

evolution
Testing Natural Selection

Biologists working with the most sophisticated genetic tools


are demonstrating that natural selection plays a greater role in
the evolution of genes than even most evolutionists had
thought

evolution
From Atoms to Traits

Charles Darwin saw that random variations in organisms


provide fodder for evolution. Modern scientists are revealing
how that diversity arises from changes to DNA and can add
up to complex creatures or even cultures

evolution
The Human Pedigree

Some 180 years after unearthing the first human fossil,


paleontologists have amassed a formidable record of our
forebears

evolution
This Old Body

Evolutionary hand-me-downs inherited from fish and


tadpoles have left us with hernias, hiccups and other maladies

evolution
What Will Become of Homo sapiens?

Contrary to popular belief, humans continue to evolve. Our


bodies and brains are not the same as our ancestors
wereor as our descendants will be

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evolution
Four Fallacies of Pop Evolutionary
Psychology

Some evolutionary psychologists have made widely


popularized claims about how the human mind evolved, but
other scholars argue that the grand claims lack solid evidence

evolution
Evolution in the Everyday World

Understanding of evolution is fostering powerful technologies


for health care, law enforcement, ecology, and all manner of
optimization and design problems

evolution
The Science of Spore

A computer game illustrates the difference between building


your own simulated creature and real-life natural selection

evolution
The Latest Face of Creationism

Creationists who want religious ideas taught as scientific fact


in public schools continue to adapt to courtroom defeats by
hiding their true aims under ever changing guises

Insights: A Theory of a Deadly Fusion

The ability to spread underlies the killing power of cancer.


The process occurs, John Pawelek thinks, when tumor cells
fuse with white blood cells an idea that, if right, could yield
new therapies

Working Knowledge: New Designs


Going Up

Elevators

Ask The Experts

How does solar power work? Why does my voice sound so


different when it is recorded and played back?

Dec 2008
planetary science
The Restless World of Enceladus

Wrinkled landscapes and spouting jets on Saturns sixthlargest moon hint at underground waters

biotech
A New Molecule of Life

Peptide nucleic acid, a synthetic hybrid of protein and DNA,


could form the basis of a new class of drugsand of artificial
life unlike anything found in nature

neuroscience
The Magic and the Brain

Magicians have been testing and exploiting the limits of


cognition and attention for hundreds of years. Neuroscientists
are just beginning to catch up

microscopy
The Light Fantastic

Biological specimens yield extraordinary images in the hands


of talented light microscopists

auto tech
Driving Toward Crashless Cars

Next-generation automotive safety technology could give us


vehicles that are difficult to crashand eventually may not
need drivers at all

biology
Taking Wing

At last, fossil and genetic findings elucidate the evolution of


bats--and settle a long-standing debate over the origins of
flight and echolocation

info tech
Can Phishing be Foiled?

Understanding the human factors that make people


vulnerable to online criminals can improve both security
training and technology

Insights: Turning Back the Cellular


Clock

Shinya Yamanaka discovered how to revert adult cells to an


embryonic state. These induced pluripotent stem cells might
soon supplant their embryonic cousins in therapeutic promise

Working Knowledge: Global Positioning


Where on Earth You Are
System

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Nov 2008
geoengineering
A Sunshade for Planet Earth

Global warming has become such an overriding emergency


that some climate experts are willing to consider schemes for
partly shielding the planet from the suns rays. But no such
scheme is a magic bullet

neuroscience
Jacking into the Brain

How far can science advance brain-machine interface


technology? Will we one day pipe the latest blog entry or
NASCAR highlights directly into the human brain as if the
organ were an outsize flash drive?

physics
The Long Arm of the Second Law

In seeming defiance of the second law of thermodynamics,


nature is filled with examples of order emerging from chaos.
A new theoretical framework resolves the apparent paradox

medicine
The Vaccine Search Goes On

The unfinished quest for an AIDS vaccine has become a


search for new approaches to the problem

medicine
Can HIV Be Cured?

Eliminating HIV from the body would require flushing the


virus out of its hiding places and preventing those reservoirs
from being refilled. A tall order but perhaps not impossible

information science
DNA Computers for Work and Play

Logic gates made of DNA could one day operate in your


bloodstream, collectively making medical decisions and
taking action. For now, they play a mean game of in vitro
tic-tac-toe

innovations
The Incredible Shrinking Scanner

A portable version of a room-size nuclear magnetic resonance


machine can probe the chemistry and structure of objects
ranging from mummies to tires

Insights: The Christian Man's Evolution

A geneticist ordained as a Dominican priest, Francisco J.


Ayala sees no conflict between Darwinism and faith.
Convincing most of the American public of that remains the
challenge

Working Knowledge: Dinner and a


Show

Microwave Ovens

Oct 2008
cosmology
Follow the Bouncing Universe

Our universe may have started not with a big bang but with a
big bouncean implosion that triggered an explosion, all
driven by exotic quantum-gravitational effects

neuroscience
Lighting Up the Brain

A clever combination of optics and genetics is allowing


neuroscientists to mapand even controlbrain circuits
with unprecedented precision

geology
Birth of an Ocean

Formation of an ocean is a rare event, one few scientists have


ever witnessed. Yet this geophysical nativity is unfolding
today in one of the hottest and most inhospitable corners of
the globe. Visit the site in safety through this extraordinary
photographic essay

neuroscience
The Search for Intelligence

IQ is easy to measure and reflects something real. But


scientists hunting among our genes for the factors that shape
intelligence are discovering they are more elusive than

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expected
info tech
Web Science Emerges

Studying the Web will reveal better ways to exploit


information, prevent identity theft, revolutionize industry and
manage our ever growing online lives

life science
Barcode of Life

Inspired by commercial barcodes, DNA tags could provide a


quick, inexpensive way to identify species

innovations
With Open-Source Arms

A community of engineers, designers and innovators is


collaborating online to make better prosthetic hands and arms
for amputees. One of the lead engineers lost his own arm in
Iraq

How did self-replicating molecules come to dominate the


Insights: Outcalculating the Competition early earth? Using the mathematics of evolutionary dynamics,
Martin A. Nowak can explain the change from no life to life
Working Knowledge: Competing
Candidates

Voting machines

Sep 2008
technology
Privacy in an Age of Terabytes and
Terror

Our jittery state since 9/11, coupled with the Internet


revolution, is shifting the boundaries between public interest
and "the right to be let alone"

technology
Reflections on Privacy 2.0

Many issues posing as questions of privacy can turn out to be


matters of security, health policy, insurance or
self-presentation. It is useful to clarify those issues before
focusing on privacy itself

technology
Brave New World of Wiretapping

As telephone conversations have moved to the Internet, so


have those who want to listen in. But the technology needed
to do so would entail a dangerous expansion of the
governments surveillance powers

medicine
Keeping Your Genes Private

In spite of recent legislation, tougher laws are needed to


prevent insurers and employers from discriminating on the
basis of genetic tests

surveillance
Tools of the Spy Trade

Night-vision cameras, biometric sensors and other gadgets


already give snoops access to private spaces. Coming soon:
palm-size "bug-bots"

technology
RFID Tag--You're It

Tiny radio-frequency identification tags, long used for


tracking supplies and inventory, are now appearing in a
growing range of consumer items. A privacy activist argues
that the devices pose new security risks to those who carry
them, often unwittingly

biometrics
Beyond Fingerprinting

Security systems based on anatomical and behavioral


characteristics may offer the best defense against identity
theft

computing
Information of the World, Unite

Mashing everyones personal data, from credit-card bills to


cell phone logs,into one all-encompassing digital dossier is the
stuff of Orwellian nightmares. But it is not as easy as most
people assume

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cryptography
How to Keep Secrets Safe

A versatile range of software solutions can protect the


privacy of your information and online activities to any
desired degree

Improving Online Security

To protect against more numerous and sophisticated attacks


by hackers, security professionals call for upgraded
technology along with more attention to human and legal
factors

The End of Privacy

Young people share the most intimate details of personal life


on social-networking Web sites, portending a realignment of
the public and the private

Insights: Safety Dance over Plastic

Just how harmful are baby bottles, eyeglasses and other


bisphenol-A plastics? Patricia Hunt, who helped to bring the
issue to light a decade ago, is still trying to sort it all out

Working Knowledge: Dry Dyes

Instant photo developing

Aug 2008
environment
Facing the Freshwater Crisis

As demand for freshwater soars, planetary supplies are


becoming unpredictable. Existing technologies could avert a
global water crisis, but they must be implemented soon

medicine
Why Migraines Strike

Biologists finally are unraveling the medical mysteries of


migraine, from aura to pain

quantum physics
Quantum Computing with Ions

Researchers are taking the first steps toward building


ultrapowerful computers that use individual atoms to perform
calculations

public health
China's Children of Smoke

Epidemiologists find molecular clues to air pollution's impact


on youngsters

planetary science
Bracing for a Solar Superstorm

A recurrence of the 1859 solar superstorm would be a cosmic


Katrina, causing billions of dollars of damage to satellites,
power grids and radio communications

materials science
Self-Cleaning Materials

The lotus plant's magnificent ability to repel dirt has inspired


a range of self-cleaning and antibacterial technologies that
may also help control microfluidic "lab-on-a-chip" devices

innovations
Magnifying Taste

Compounds that enhance the sweet and salty flavors of foods


could combat obesity and heart disease

Insights: No More Cloning Around

Like many stem cell pioneers, Ian Wilmut, the creator of


Dolly the sheep, has jumped to an alternative approach. Is
this the beginning of the end for embryonic cloning?

Working Knowledge: Warming and


Cooling

Home heat pumps

Jul 2008
physics
The Self-Organizing Quantum

A new approach to the decades-old problem of quantum


gravity goes back to basics and shows how the building
blocks of space and time pull themselves together

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medicine
New Jobs for Ancient Chaperones

Protective heat shock proteins present in every cell have long


been known to counteract stress. Newly recognized roles in
cancer and immunity make them potential therapeutic allies

anthropology
Traces of a Distant Past

DNA furnishes an ever clearer picture of the multimillennial


trek from Africa all the way to the tip of South America

innovations
Hands On Computing

Multi-touch screens could improve collaboration without a


mouse or keyboard

agriculture
No-Till: The Quiet Revolution

The age-old practice of turning the soil before planting a new


crop is a leading cause of farmland degradation. Many
farmers are thus looking to make plowing a thing of the past

neuroscience
The Neuroscience of Dance

Recent brain-imaging reveal some of the complex neural


choreography behind our ability to dance

mathematics
Simple Groups at Play

A new set of puzzles inspired by Rubiks Cube offers puzzle


lovers the chance to get acquainted with the secret twists and
turns of mathematical entities called sporadic simple groups

Going with His Gut Bacteria

The body and its intestinal flora produce chemicals with


hidden health information, Jeremy Nicholson has found.
Someday treating disease may mean treating those bacteria

Working Knowledge: Nimble


Skyscrapers at Sea

Cruise ships

Jun 2008
cosmology
The Cosmic Origins of Time's Arrow

One of the most basic facts of life is that the future looks
different from the past. But on a grand cosmological scale,
they may look the same

medicine
Gaining Ground on Breast Cancer

The newest targeted therapies are helping doctors to tailor


increasingly effective treatments to individual patients

info tech
Digital Image Forensics

Modern software has made manipulation of photographs


easier to carry out and harder to uncover than ever before,
but the technology also enables new methods of detecting
doctored images

biology
What Is a Species?

To this day, scientists struggle with that question. A better


definition can influence which animals make the endangered
list

astronomy
The Tunguska Mystery

Finding a piece of the elusive cosmic body that devastated a


Siberian forest a century ago could help save the earth in the
centuries to come

neuroscience
The Neurobiology of Trust

Our inclination to trust a stranger stems in large part from


exposure to a small molecule known for an entirely different
task: inducing labor

policy
The Ethics of Climate Change

Weighing our own prosperity against the chances that climate


change will diminish the well-being of our grandchildren calls
on economists to make hard ethical judgments

Walter Fiers found a protein segment on the influenza virus


Insights: Beating the Flu in a Single Shot that could lead to a universal flu vaccine, which would end

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seasonal shots and provide pandemic protection


Working Knowledge: Library to Go

E-Book Readers

May 2008

astronomy
The Genesis of Planets

Theorists long imagined that the formation of young solar


systems was a serene process with a stately progression, in
which the eventual appearance of planets was a foregone
conclusion. The latest evidence, however--including
observations of worlds circling other stars--argues that planet
formation is startlingly chaotic

evolution
Regulating Evolution

Most animals share similar genes. The staggering diversity in


their physical forms springs from switches in the DNA that
govern where and when those genes are active

info tech
Science 2.0

Is posting raw experimental data online, for all to see, a great


tool or a great risk?

biology
How Cells Clean House

Autophagy, a process that normally keeps cells in good


working order, seems to be linked to aging and diseases such
as Alzheimer's

neuroscience
Hooked from the First Cigarette

Cigarette addiction can arise astonishingly fast. New research


could help make quitting easier

nuclear policy
Rethinking Nuclear Fuel Recycling

Plans are afoot to reuse spent reactor fuel in the U.S. But the
advantages of the scheme pale in comparison with its dangers

health
Fighting Killer Worms

Bloodsucking worms called schistosomes are among the


world's most worrisome human parasites. A new genome
sequence and powerful genetic tools promise to help crack
their secrets

Insights: Dark Forces at Work

The universe will expand forever at an ever faster rate,


thanks to an unseen energy. Astronomer Saul Perlmutter
expects that new observations will soon illuminate the
universe's dark side

Working Knowledge: Living Cover

Green roofs

Apr 2008

space science
The Color of Plants on Other Worlds

If it isn't easy being green on Earth, where chlorophyll is well


tuned to absorb most of the energy in our sun's yellow light,
imagine the difficulties elsewhere in the galaxy. Plants
growing on worlds around cooler, brighter or more
tempestuous stars would need to rely on red, blue or even
black pigments to survive. That insight offers astronomers
new clues about what to look for in their search for
extraterrestrial life

medicine
Regrowing Human Limbs

The ability to regenerate lost body parts--salamanderstyle--could revolutionize the treatment of amputations and
major wounds

ecology
Reclaiming the Aral Sea

Mismanagement turned the world's fourth-largest lake into a


dry, toxic wasteland. Now the northern part, at least, is
coming back

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physics
Rulers of Light

A kind of laser light called an optical frequency comb can


make atomic clocks and other instruments much more precise

psychology
The Doping Dilemma

Game theory suggests how to stop the pervasive abuse of


drugs in cycling, baseball and other sports

materials science
Carbon Wonderland

A newly recognized form of carbon--single sheets of atoms-provides a rich lode of novel theoretical physics and practical
applications

national security
Detecting Nuclear Smuggling

Radiation monitors at U.S. ports cannot reliably detect highly


enriched uranium, which onshore terrorists could assemble
into a nuclear bomb

Insights: At the Edge of Life's Code

What happens in the black box between DNA and the


proteins it produces? Chris Wiggins uses machine-learning
techniques to peer inside

Working Knowledge: Weapons


Revealed

Whole-body scanning for airline passengers

Mar 2008
economics
When Markets Beat the Polls

Internet-based financial markets may predict elections more


reliably than polls do. They can augur future box-office
returns and flu seasons, too.

cosmology
The End of Cosmology?

"Will the big bang be forgotten? The accelerating cosmic


expansion is wiping away every trace of the universe's
origin."

neuroscience
White Matter Matters

Long regarded as passive support for cogitating neurons, the


brain's white matter shows that it actively affects learning and
mental illness.

info tech
The Limits of Quantum Computers

Futuristic quantum computers could be exceptionally fast at


certain tasks, but for most problems they would only
modestly outclass today's conventional machines.

environment
The Bluefin in Peril

The only way to save the bluefin tuna, a marvelous but


dwindling ocean fish, may be to domesticate it.

defense
Space Wars

Recent pronouncements and actions by the U.S. and China


threaten to ignite a new arms race in space that would be
contrary to everyone's interests.

public health
Soliving the Massive Worker Health
Puzzle

A sophisticated industrial health study--the largest one ever-struggles with an apparent cancer cluster and highlights why
science cannot always protect workers on the job.

Insights: Not Tonight, Dear, I Have to


Reboot

Is love and marriage with robots an institute you can


disparage? Computing pioneer David Levy doesn't think
so--he expects people to wed droids by midcentury. Is that a
good thing?

Working Knowledge: The Switch Is On

The switch is on to compact fluorescents.

Feb 2008

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physics
The Discovery Machine

The Large Hadron Collider, the biggest and most complicated


particle physics experiment ever seen, is nearing completion
and is scheduled to start colliding protons this year

physics
The Coming Revolutions in Particle
Physics

No matter what the Large Hadron Collider finds, it is going to


take physics into new territory

physics
Building the Next-Generation Collider

To further investigate the intricacies of high-energy particle


physics, researchers must construct a more powerful
electron-positron collider

climate change
The Unquiet Ice

Abundant liquid water discovered underneath the great polar


ice sheets could catastrophically intensify the effects of
global warming on the rise of sea level around the world

innovations
RFID Powder

Radio-frequency identification (RFID) tags label all kinds of


inventoried goods and speed commuters through toll plazas.
Now tiny RFID components are being developed with a
rather different aim: thwarting counterfeiters

medicine
Your Cells Are My Cells

Many, perhaps all, people harbor a small number of cells from


genetically different individuals--from their mothers and, for
women who have been pregnant, from their children. What in
the world do these foreigners do in the body?

science and society


Building a Future on Science

Brazilian neuroscientist Miguel A. L. Nicolelis taps into the


chatter of neurons to drive robotic prosthetics. Now he hopes
to tap the potential of his country's population by building a
network of "science cities"

Insights: Maverick against the


Mendelians

Autistic people generally do not have children, so why do


autism genes persist? Michael Wigler thinks that he knows

Working Knowledge: Leap of Faith

The video magic of blue screen

Jan 2008
tech leaders
The SciAm 50

Which researchers, companies and architects of industrial


and government policy are leading the most important trends
shaping tomorrow's technologies? Our annual roundup of
world shakers gives credit where it is due

medicine
Taming Vessels to Treat Cancer

Drugs that restore order to the chaotic blood vessels inside a


tumor open a window of opportunity for attacking it

energy
A Solar Grand Plan

An ambitious scheme would enable solar power to end U.S.


dependence on foreign oil and slash greenhouse gas emissions
by 2050

public health
Second Thoughts about Fluoride

New research indicates that a cavity-fighting treatment could


be risky if overused

nanotech
Self-Powered Nanotech

Tiny systems that draw waste energy from their surroundings


could power nanosize machines

earth science
Hotspots Unplugged

Long considered fixed founts of molten material from deep


within the planet, the hotspots that raise islands now join the
list of the earth's moving parts

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physiology
The Human Instrument

When judged by its size, our vocal system fails to impress as


a musical instrument. How, then, can it produce all those
remarkable sounds?

Insights: Cooking Up Bigger Brains

Our hominid ancestors could never have eaten enough raw


food to create our large, calorie-hungry brains, Richard
Wrangham claims. The secret to our evolution, this
anthropologist says, is cooking

Working Knowledge: Perpetual Reset


Machine

The striking mechanics of bowling pinsetters

Dec 2007
astronomy
Window on the Extreme Universe

The GLAST satellite is about to open up an unexplored


region of the electromagnetic spectrum, where dark matter
and other mysteries might be seen

biology
Are Aliens among Us?

All life on Earth is generally understood to have descended


from a common ancestor. But if cells evolved independently
more than once, some microbes radically different from all
known organisms might still survive in extreme environments
of our planet. The search is on for evidence of these strangers

environment
Making Carbon Markets Work

Limiting climate change without damaging the world


economy depends on stronger and smarter market signals to
regulate carbon dioxide

gallery
Radiant Information

State-of-the-art light microscopy from the Olympus


BioScapes competition illuminates life exquisitely

genetics
Diet Advice from DNA?

Are personalized diets based on genetic tests cutting-edge


science or high-tech horoscopes?

info tech
The Semantic Web in Action

Networks that handle data more intelligently are already here

physics
The Many Worlds of Hugh Everett

Whatever became of the creator of the now celebrated


quantum theory of multiple universes?

Working Knowledge: Progress


Accelerates

Adaptive cruise control

Nov 2007
cosmology
The Great Cosmic Roller-Coaster Ride

Could cosmic inflation be a sign that our universe is in a far


vaster realm?

biology
Cell Defenses and the Sunshine Vitamin

Scientists now recognize that vitamin D does much more than


build strong bones and that many people are not getting
enough of it

weaponry
Nuclear Weapons in a New World

Countries are altering their nuclear arsenals, prompting the


U.S. to refurbish its own warheads

weaponry
The Nuclear Threat

A look at strike capabilities worldwide, and how a bomb


would affect single cities and people

weaponry
A Need for New Warheads?

The U.S. government's proposal to build the first new muclear


warhead in two decades raises a host of questions

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medicine
Playing Defense against Lou Gehrig's
Disease

Researchers have proposed potential therapies for a


paralyzing disorder once thought to be untreatable

info tech
Brilliant Displays

A new technology can make cell phone and other displays


bright and clear, even in the sun's glare

science and society


The Science of Doing Good

Information technology, satellite imaging and research carried


out in disaster-relief areas have begun to transform
humanitarian aid into a more efficient endeavor

Working Knowledge: Two Technologies


Shine

Digital projectors shine

Oct 2007
environment
Conservation for the People

Pitting nature and biodiversity against people makes little


sense. Many conservationists now argue that human health
and well-being should be central to conservation efforts

space exploration
The Future of Space Exploration

The launch of the Soviet Sputnik satellite half a century ago


inaugurated the Space Age. What comes next?

space exploration
To the Moon and Beyond

Humans are returning to the moon. This time the plan is to


stay a while

space exploration
Five Essential Things to Do in Space

Planetary scientists have a quintet of goals for exploring the


solar system

psychology
How Does Consciousness Happen?

One of the greatest mysteries in science is how brain activity


gives rise to subjective experience. Two leading
neuroscientists compare their differing theories

physics
The Diamond Age of Spintronics

Revolutionary electronic devices can harness the spins of


electrons instead of their charge. Such devices might one day
enable room-temperature quantum computers--made of
diamond

medicine
Experimental Drugs on Trial

A controversial lawsuit challenges the FDA's system of


controlling access to experimental drugs and, some say, the
scientific basis of drug approval

innovations
Big Lab on a Tiny Chip

Squeezing a chemistry lab down to fingernail size could


provide instant medical tests at home and on the battlefield

Working Knowledge: Heating Up

Geothermal energy

Sep 2007
sustainability
A Question of Sustenance

Globalization ushered in a world in which more than a billion


are overfed. Yet 800 million or so still suffer from hunger's
persistent scourge

nutrition
Eating Made Simple

How do you cope with a mountain of conflicting diet advice?


Also: Paul Raeburn reviews the best scientific guidance on
weight loss

health
Can Fat Be Fit?

Popular books have questioned the ill effects of being


overweight. They are probably wrong

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physiology
What Fuels Fat

Understanding obesity as a breakdown in the body's weight


regulation could yield new ways to fight fat

nutrition
This Is Your Brain on Food

Neuroimaging reveals what chocoholics have in common


with drug addicts. Interview with Nora D. Volkow

public health
The World Is Fat

How can the poorest countries fight obesity?

nutrition
Still Hungry

One eighth of the world does not have enough to eat

biotech
Sowing a Gene Revolution

A new green revolution based on genetically modified crops


could help reduce poverty and hunger, but only if formidable
institutional challenges are met

security
Is Your Food Contaminated?

New approaches to protect the food supply

Working Knowledge: Fresh from the Sea Desalination of seawater


Aug 2007
policy
Race in a Bottle

Drugmakers are eager to develop medicines targeted at ethnic


groups, but so far they have made poor choices based on
unsound science

modelling
Predicting Wildfires

Fires are burning more acres than ever. Where will the next
blazes ignite? Can we prevent them? Should we?

neuroscience
Windows on the Mind

Tiny flicks of the eyes underpin much of our ability to see.


They may also reveal subliminal thoughts

environment
The Physical Science behind Climate
Change

Why climatologists are now so confident that human activity


is to blame for a warming world

biology
The Shark's Electric Sense

An astonishingly sensitive detector of electric fields helps


sharks zero in on prey

agriculture
Future Farming: A Return to Roots?

Agriculture would become more sustainable if major crop


plants built deep, lasting root systems

innovations
Data Center in a Box

A shipping container stuffed with servers could usher in the


era of cloud computing

Working Knowledge: Blu-ray vs. HD


DVD

High-definition video

Jul 2007
climate change
Warmer Oceans, Stronger Hurricanes

Evidence is mounting that global warming enhances a


cyclone's damaging winds and flooding rains

neuroscience
The Memory Code

Researchers are closing in on the rules that the brain uses to


lay down memories. Discovery of this memory code could
lead to new ways to peer into the mind

medicine
A Malignant Flame

Understanding chronic inflammation, which contributes to


heart disease, Alzheimer's and other ailments, may be a key
to unlocking the mysteries of cancer

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genetics
The Evolution of Cats

Genomic paw prints in the DNA of the world's wild cats have
clarified the feline family tree and uncovered several
remarkable migrations in their past

environment
An Earth without People

Interview with Alan Weisman. One way to examine


humanity's impact on the environment is to consider how the
world would fare if all the people disappeared

info tech
Broadband Room Service by Light

Encoded light transmissions can provide the wireless devices


in a room with multimedia Web services

science and society


Should Science Speak to Faith?

Two prominent defenders of science discuss how scientists


ought to approach believers

Working Knowledge: In or Out?

Hawkeye on the tennis court

Jun 2007
biology
A Simpler Origin for Life

Energy-driven networks of small molecules may be more


likely first steps for life than the commonly held idea of the
sudden emergence of large self-replicating molecules such as
RNA

medicine
Lifting the Fog around Anesthesia

Learning why current anesthetics are so potent and


sometimes dangerous will lead to a new generation of safer
targeted drugs

cosmology
When Fields Collide

The history of particle cosmology shows that science can


benefit from wrenching changes

ecosystems
Restoring America's Big, Wild Animals

Pleistocene rewilding--a proposal to bring back animals that


disappeared from North America 13,000 years ago--offers an
optimistic agenda for 21st-century conservation

info tech
Breaking Network Logjams

Network coding could dramatically enhance the efficiency of


communications networks

innovations
Seeing Triple

Anticipated for decades, machines are finally displaying


objects in three true dimensions

game theory
The Traveler's Dilemma

People playing this simple game consistently reject the


rational choice. In fact, by acting illogically, they end up
reaping a larger reward--an outcome that demands a new kind
of formal reasoning

Working Knowledge: The Write Type

Optical character recognition finds the write type

May 2007
space science
The Mystery of Methane on Mars and
Titan

Could the methane in the atmospheres of Mars and Titan be


caused by unusual geologic activity--or life?

medicine
Chromosomal Chaos and Cancer

Current wisdom on the role of genes in malignancy may not


explain some of the features of cancer, but stepping back to
look at the bigger picture inside cells reveals a view that just
might

energy
Preventing Blackouts

A smarter power grid that automatically responds to problems


could reduce the rising number of debilitating blackouts

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paleontology
South America's Missing Mammals

An unexpected menagerie of unique mammal fossils is


overturning long-held ideas about South America's geologic
history

info tech, nanotech


Carbon Nanonets Spark New
Electronics

Random networks of tiny carbon tubes could make possible


low-cost, flexible devices such as "electronic paper" and
printable solar cells

neuroscience
Eyes Open, Brain Shut

Brain-imaging techniques yield a better understanding of


patients in the vegetative state

physics
A Do-It-Yourself Quantum Eraser

Carry out a home experiment to illustrate one of the weirdest


effects in quantum mechanics

Working Knowledge: Psst ... Hey, You

Beams of sound

Apr 2007
astronomy
The Ghosts of Galaxies Past

Strangely moving stars may be the remnants of past galaxies


devoured by our Milky Way

biotech
Seeking the Connections: Alcoholism
and Our Genes

Identifying the genetic influences on vulnerability to alcohol


addiction can lead to more targeted treatments and help
individuals make better-informed choices

info tech
The Promise of Plasmonics

A technology that squeezes electromagnetic waves into


minuscule structures may yield superfast computer chips,
ultrasensitive molecular detectors and perhaps even
invisibility cloaks

animal behavior
Just How Smart Are Ravens?

Recent experiments show that these birds use logic to solve


problems and that some of their abilities approach or surpass
those of the great apes

neuroscience
The Movies in Our Eyes

The retina processes information much more than anyone has


ever imagined, sending a dozen different movies to the brain

energy
Gassing Up with Hydrogen

Researchers are working on ways for fuel-cell vehicles to


hold the hydrogen they need for long-distance travel

medicine
A Cure for Rabies?

The survival of a Wisconsin teenager who contracted rabies


may point the way to a treatment for this horrifying disease

Working Knowledge: Steer Clear

Electronic stability control for autos

Technicalities: The Car Doctor Is In

A way to diagnose engine problems without ever having to


look under the hood

Mar 2007
astrophysics
Black Hole Blowback

A single black hole, smaller than the solar system, can control
the destiny of an entire cluster of galaxies

biotech
Mapping the Cancer Genome

The Cancer Genome Atlas will help chart a new course


across the complex landscape of human malignancies

info tech
A Digital Life

New systems may allow people to record everything that has


touched their lives and to store all these data in a personal
digital archive

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environment
Down Go the Dams

Many dams are being torn down these days, allowing rivers
and the ecosystems they support to rebound. But ecological
risks abound as well. Can they be averted?

medicine
New Predictors of Disease

Predictive autoantibodies appear in the blood years before


people show symptoms of various disorders. Tests that
detected these molecules could warn of the need to take
preventive action

energy
Diesels Come Clean

Improved engines and exhaust scrubbers, combined with a


new fuel, will make energy-efficient diesels nearly as green as
hybrids

neuroscience
Illusory Color and the Brain

The brain may not separate perception of color from


perception of form and depth

Working Knowledge: Restoring Flow

Left ventricular assist devices

Feb 2007
cosmology
The Universe's Invisible Hand

Dark energy does more than hurry along the expansion of the
universe. It also has a stranglehold on the shape and spacing
of galaxies

paleontology
Tracking an Ancient Killer

The case was cold--the bones in the mass grave were 70


million years old. But critical clues pointed to the killer's
identity

climate change
Methane, Plants and Climate Change

The surprising discovery that living plants produce a potent


greenhouse gas poses new questions for managing global
warming

info tech
Making Silicon Lase

Scientists have at last persuaded silicon to emit laser beams.


In a few years, computers and other devices will handle light
as well as electrons

innovations
Spice Healer

An ingredient in curry shows promise for treating


Alzheimer's, cancer and other diseases

consumer electronics
Digital TV at Last?

Analog TV broadcasting is set to end in two years, but its


legacy could make the digital transition anything but smooth

nanotech
Molecular Lego

Small molecular building blocks that snap together rigidly


enable chemists to design and manufacture nanometer-scale
structures in virtually any shape

Working Knowledge: Song Beams

Satellite radio

Technicalities: Power Walker

Nothing could match the Segway's initial hype, but how far
has it come since?

Jan 2007
astrophysics
What Is a Planet?

The controversial new official definition of "planet," which


banished Pluto, has its flaws but by and large captures
essential scientific principles

energy
Is Ethanol for the Long Haul?

Ethanol could displace gasoline, but it won't pay off until we


find a way to distill cornstalks, not corn.

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molecular biology
The Power of Riboswitches

Recently discovered RNA segments that act like on-off


switches for genes may be targets for new classes of drugs

info tech
A Robot in Every Home

Microsoft's founding CEO predicts that robotics is on the


verge of a grand awakening and that intelligent mobile
devices will soon be everywhere

life science
Evolved for Cancer?

Some scientists hope to find new clues to help fight cancer by


studying the evolutionary history of the disorder in our
species

earth science
The Mississippi's Curious Origins

Mountains once blocked the interior of North America from


the south. Geologic sleuthing reveals how that barrier was
breached, allowing the Mississippi to reach the Gulf of
Mexico

innovations
Better Ways to Target Pain

Improved understanding of the chemical pathway on which


aspirin and Vioxx act may lead to superior analgesics

Working Knowledge: Grass vs. Plastic

High-tech turf

Dec 2006
tech leaders
The Scientific American 50

Nanotech viruses, global warming, greener cars, stem cells


and innovative funding all take a bow in our fifth annual
salute to the research, business and policy leaders of
technology

planetary science
The Red Planet's Watery Past

For a billion years, liquid water may have covered much of


Mars

neuroscience
Seeking the Neural Code

How does a storm of electrical pulses in the brain translate


into information?

paleontology
Lucy's Baby

An amazing skeleton from 3.3 million years ago renews


debate over the evolution of upright walking

photonics
The Ultimate White Light

"Supercontinuum" laser light could drive optical data


transmission to record speeds

medicine
Cancer Clues from Pet Dogs

Studies of canine malignancies could improve medical care


for humans and man's best friend alike

metrology
Weighty Matters

Replacing the century-old standard reference for mass


measurement is a heavy challenge

Working Knowledge: Hot Commodity

Why lithium batteries can overheat

Nov 2006
cosmology
The Dark Ages of the Universe

Between the big bang and the formation of the first stars, the
cosmos was utterly lightless. But astronomers can finally start
peering into the darkness

neuroscience
Mirrors in the Mind

Mirror neurons, a special class of cells in the brain, may


mediate our ability to mimic, learn and understand the actions
and intentions of others

neuroscience
Broken Mirrors: A Theory of Autism

When the brain's mirror neuron system malfunctions, perhaps


lack of empathy and other characteristics of autism are the
result

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info tech
Malware Goes Mobile

Consumers, phone makers and security companies must


move quickly to quash the threat of new viruses targeting
mobile devices

ecology
Reviving Dead Zones

Around the world, nutrients in runoff are turning coastal sea


areas into oxygen-deprived dead zones hostile to life. But the
example of the Black Sea shows these regions can be saved

technology
Seeing with Superconductors

Sensors made of superconducting material can detect


individual photons and have applications ranging from
antiterrorism to astronomy

astronomy
The Origin of the Greek Constellations

Was the Great Bear constellation named before hunter


nomads first reached the Americas more than 13,000 years
ago?

Working Knowledge: Gunk-Free Fiber

The sticky problem of paper recycling

Oct 2006
astrophysics
How to Blow Up a Star

It is not as easy as you would think. Models of supernovae


have failed to reproduce these explosions--until recently

info tech, nanotech


Viral Nanoelectronics

Viruses that coat themselves in selected substances can


self-assemble into such devices as liquid crystals, nanowires
and electrodes

cell biology
Peacekeepers of the Immune System

Regulatory T cells keep the immune system from attacking


the body itself. Therapies using these cells could ease
conditions from diabetes to transplant rejection

earth science
Impact from the Deep

Strangling heat and gases from the earth and sea, not
asteroids, most likely caused several ancient mass extinctions.
Could the same conditions build again?

robotics
Ballbots

A new mode of locomotion would enable robots to stand tall


and move gracefully through busy everyday environments

anthropology
Hydraulic Engineering in Prehistoric
Mexico

Three thousand years ago precursors of the Aztecs built the


first large-scale water management systems in the New World

biotech
The Promise of Molecular Imprinting

Tiny plastic imprints and mimics of biological molecules


could speed drug discovery, warn of bioterror attacks and
remove toxins from the environment

Working Knowledge: Steady Cam

Image stabilization in digital cameras

Sep 2006
energy
A Climate Repair Manual

Coping with global warming will take innovations in both


energy technology and policy

energy
A Plan to Keep Carbon in Check

Multiple technologies, each taking a slice out of carbon


dioxide emissions, could slow warming

energy
Fueling Our Transportation Future

New technologies, lighter vehicles and alternative fuels can


lower greenhouse gas releases from cars and trucks

energy
An Efficient Solution

In buildings and in industrial processes, using power more


judiciously is the quickest, cheapest solution

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energy
What to Do about Coal

Coal is plentiful, but we must manage its environmental dark


side

energy
The Nuclear Option

Nuclear power could stave off more than a billion tons of


carbon emissions annually

energy
The Rise of Renewable Energy

Solar cells, wind turbines and biofuels are poised to become


major energy sources

energy
High Hopes for Hydrogen

Hydrogen-fueled cars could slash carbon emissions, but it


won't happen soon

energy
Plan B for Energy

Eventually, even more radical energy sources will be needed.


Here are some possibilities under consideration

Working Knowledge: Tall Task

A tall task for water towers

Aug 2006
astronomy
The Strangest Satellites in the Solar
System

With peculiar orbits that often move against the grain of the
rest of the solar system, an odd breed of planetary satellites is
reshaping ideas about the formation of the solar system

life science
The Real Life of Pseudogenes

Disabled genes, once dismissed as detritus on the genomic


landscape, trace the path of evolution--and may not always
be entirely dead

space science
Power for a Space Plane

Creating a revolutionary hypersonic jet engine that could


propel a space plane to orbit affordably and routinely is a
tough but seemingly achievable task

psychology, neuroscience
The Expert Mind

The mental processes of chess grandmasters are unlike those


of novices, a fact that illuminates the development of
expertise in other fields

New studies of the Himalaya and the Tibetan Plateau suggest


earth science
that climate and geology can be partners in a long, slow
Climate and the Evolution of Mountains
dance
info tech
A Great Leap in Graphics

Soon even home computers should be able to produce quick,


high-quality 3-D graphics, thanks to speedier new ways to
simulate the flight of light

ecology
The Fish and the Forest

Salmon carcasses left behind by predatory bears are


unexpectedly important sources of nutrients for forests

Working Knowledge: Going Vertical

How disk-drive makers raise storage capacities by making


bits stand on end

Technicalites: Weather Gets Personal

Here's the five-day forecast for your backyard

Jul 2006
astronomy
Hubble's Top 10

As they wait for the space telescope to be serviced one last


time, astronomers reflect on its discoveries over the past 16
years

medicine
Stem Cells: The Real Culprits in
Cancer?

A dark side of stem cells--their potential to turn malignant--is


at the root of a handful of cancers and may be the cause of
many more. Eliminating the disease could depend on tracking
down and destroying these elusive killer cells

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physics, optics
The Quest for the Superlens

Built from "metamaterials" with bizarre, controversial optical


properties, a superlens could produce images that include
details finer than the wavelength of light that is used

life science
What Birds See

Evolution has endowed birds with a system of color vision


that surpasses that of all mammals, including humans

energy
A Power Grid for the Hydrogen
Economy

Cryogenic, superconducting conduits could be connected into


a "SuperGrid" that would simultaneously deliver electrical
power and hydrogen fuel

forensics
CSI: Reality

Attorneys, investigators and educators have felt the impact of


television's popular forensics programs

info tech
A Farewell to Keywords

The reigning obsession with search technology has elicited


new ways of using images to track down information on the
Web

Working Knowledge: Expanding Use

Vascular stents

Jun 2006
earth science
The Secrets of Supervolcanoes

Microscopic crystals of volcanic ash are revealing surprising


clues about the world's most devastating eruptions

biotech
Engineering Life: Building a Fab for
Biology

Principles and practices learned from engineering successes


can help transform biotechnology from a specialized craft
into a mature industry

ecology
Wading in Waste

Thanks to unchecked development along America's coasts,


disease-causing microbes are increasingly fouling beaches
and shellfish beds

medicine
Toward Better Pain Control

Advances in understanding the cells and molecules that


transmit pain signals are providing new targets for drugs that
could relieve various kinds of pain--including those poorly
controlled by existing therapies

info tech
Dependable Software by Design

Computers fly our airliners and run most of the world's


banking, communications, retail and manufacturing systems.
Now powerful analysis tools will at last help software
engineers ensure the reliability of their designs

medicine, pharmacology
A New Assault on HIV

The constant search for weak points in the virus yields ideas
for a wholly new class of drug

mathematics
The Science behind Sudoku

Solving a Sudoku puzzle requires no math, not even


arithmetic. Even so, the game poses a number of intriguing
mathematical problems

Working Knowledge: Carbon Hooch

Oil refineries

Technicalities: The Ultimate Blood Test

A pricey way to determine health risks: 250 tests at once

May 2006
physics, cosmology
The First Few Microseconds

In recent experiments, physicists have replicated conditions


of the infant universe--with startling results

info tech, nanotech


Bringing DNA Computer to Life

Tapping the computing power of biological molecules gives


rise to tiny machines that can speak directly to living cells

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earth science
The Birth of the Mighty Amazon

Insight into how the world's largest river formed is helping


scientist explain the extraordinary abundance of plant and
animal life in the Amazon rain forest

biotech
Blockbuster Dreams

New understanding of the biology behind a successful cancer


therapy may lead to a drug that can treat an array of solid
tumors

astronomy
Giant Telescopes of the Future

The astronomical version of Moore's law says that telescopes


double in size every few decades. But today's designers think
they can build a telescope three, five or even 10 times bigger
within a decade

medicine
Shutting Down Alzheimer's

New research reveals strategies for blocking the molecular


processes that lead to this memory-destroying disease

mathematics
When Slide Rules Ruled

Before electronic calculators, the mechanical slide rule


dominated scientific and engineering computation

Working Knowledge: Cutting Work

Robot mowers

Apr 2006
astrophysics
The Mysterious Origins of Solar Flares

New observations are beginning to reveal what triggers these


huge explosions of the sun's atmosphere

medicine
New Hope for Defeating Rotavirus

Although its name is unfamiliar to many, rotavirus is the


leading cause of severe childhood diarrhea worldwide and a
frequent killer of young children in developing nations.
Now--after 30 years of investigation--vaccines that may well
conquer it are ready for market

info tech
Computing with Quantum Knots

A machine based on bizarre particles called anyons that


represents a calculation as a set of braids in spacetime might
be a shortcut to practical quantum computation

evolution
Why Are Some Animals So Smart?

The unusual behavior of orangutans in a Sumatran swamp


suggests a surprising answer

transportation
Hybrid Vehicles Gain Traction

As car buyers turn to fuel-sipping gasoline-electric hybrid


vehicles, a new generation of greener hybrids is just coming
over the horizon

biotech
An Antibiotic Resistance Fighter

A compound that tweaks a pivotal protein may quell


development of antibiotic resistance

economics
Does Globablization Help or Hurt the
World's Poor?

The answer is: both. The real question is how to maximize the
help and minimize the hurt

Working Knowledge: Big Squeeze

Jet engines

Technicalities: Sharp Shooter

Sony's R1 combines near pro-quality images with live


preview

Mar 2006
space science
Shielding Space Travelers

The perils of cosmic rays pose severe, perhaps


insurmountable, hurdles to human spaceflight to Mars and
beyond

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biotech
Unlocking the Secrets of Longevity
Genes

A handful of genes that control the body's defenses during


hard times can also dramatically improve health and prolong
life in diverse organisms. Understanding how they work may
reveal the keys to extending human life span while banishing
diseases of old age

ecology
The Dangers of Ocean Acidification

Much of the carbon dioxide given off from the burning of


fossil fuels goes into the ocean, where it changes the acid
balance of seawater. The repercussions for marine life may be
enormous

info tech
Cognitive Radio

Smart radios and other new wireless devices will avoid


transmission bottlenecks by switching instantly to nearby
frequencies that they sense are clear

mathematics
The Limits of Reason

Ideas of complexity and randomness originally suggested by


Gottfried W. Leibniz in 1686, combined with modern
information theory, imply that there can never be a "theory of
everything" for all mathematics

chemistry
Little Green Molecules

Chemists have invented a new class of catalysts that can


destroy some of the worst pollutants before they get into the
environment

innovations, computing
The Elusive Goal of Machine
Translation

Statistical methods hold tha promise of moving computerized


translation out of the doldrums

Working Knowledge: Spin and Swing

Tiny motors

Feb 2006
physics
Plasma Accelerators

A new method of particle acceleration in which the particles


"surf" on a wave of plasma promises to unleash a wealth of
applications

physiology, immunology
Intrigue at the Immune Synapse

Images of interacting immune cells reveal structured


connections similar to the ones neurons use to communicate.
Studying these synapses is providing new insights into how
the cells form an information-sharing network to fight disease

defense
Thwarting Nuclear Terrorism

Many civilian research reactors contain highly enriched


uranium that terrorists could use to build nuclear bombs

engineering
Protecting New Orleans

Hurricanes Katrina and Rita devastated the Gulf Coast. The


storm season starts again this June--and every June. Can
coastal communities ever be safeguarded?

innovations, nanotech
Miniaturized Power

With nanobatteries, power sources finally shrink with the rest


of electronics

biotech
Owning the Stuff of Life

Patents on DNA have not caused the severe disruption of


biomedical research and societal norms anticipated by critics.
But the deluge may be yet to come

info tech
Putting a Face on the First President

Solving a surprisingly long-standing mystery, a forensic


anthropologist reconstructs what George Washington looked
like as a young man

Working Knowledge: Into the Breach

Levees

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Technicalities: My Virtual War

http://www.davelo.net/sciam/regular-index.html

A disturbing stroll through a simulated battlefield

Jan 2006
astrophysics
The Mystery of Brown Dwarf Origins

By throwinig a wrench into the theories of planet and star


formation, brown dwarfs may help fix them

biotech
Genomes for All

Next-generation technologies that make reading DNA fast,


cheap and widely accessible are coming in less than a decade.
Their potential to revolutionize research and bring about the
era of truly personalized medicine means the time to start
preparing is now

earth science
Tsunami: Wave of Change

In the tragic aftermath of the Indian Ocean tsunami of


December 2004, scientists and warning centers are now
better equipped to forecast and model these monstrous waves

robotics
Innovations from a Robot Rally

This year's Grand Challenge competition spurred advances in


laser sensing, computer vision and autonomous
navigation--not to mention a thrilling race for the $2-million
prize

neuroscience
The Maternal Brain

Pregnancy and motherhood change the structure of the


female mammal's brain, making mothers attentive to their
young and better at caring for them

info tech
Recognition Engines

New computer designs process networked "streams" of data


for better spam and virus detection

toxicology
Protecting More than Animals

Reducing animal suffering often has the unexpected benefit


of yielding more rigorous safety tests

Working Knowledge: No More Gears

Continuously variable transmission

Dec 2005
tech leaders
The Scientific American 50

Flu preparedness, flexible electronics and stem cells all star in


our fourth annual salute to the research, business and policy
leaders of technology

physics
An Echo of Black Holes

Sound waves in a fluid behave uncannily like light waves in


space. Black holes even have acoustic counterparts. Could
spacetime literally be a kind of fluid, like the ether of
pre-Einsteinian physics?

medicine
Tackling Malaria

Interventions available today could lead to decisive gains in


prevention and treatment--if only the world would apply
them

energy
Smarter Use of Nuclear Waste

Fast-neutron reactors could extract much more energy from


recycled nuclear fuel, minimize the risks of weapons
proliferation and markedly reduce the time nuclear waste
must be isolated

public health
Sick of Poverty

New studies suggest that the stress of being poor has a


staggeringly harmful influence on health

evolution
Getting a Leg Up on Land

Recent fossil discoveries cast light on the evolution of


four-limbed animals from fish

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neuroscience
Inside the Mind of a Savant

Kim Peek possesses one of the most extraordinary memories


ever recorded. Until we can explain his abilities, we cannot
pretend to understand human cognition

Working Knowledge: Better Exposure

Digital x-rays

Technicalities: Easy Rider

Automatic transmission makes cycling a breeze

Nov 2005
medicine
Preparing for a Pandemic

One day a highly contagious and lethal strain of influenza will


sweep across all humanity, claiming millions of lives. It may
arrive in months or not for years--but the next pandemic is
inevitable. Are we ready?

physics
The Illusion of Gravity

The force of gravity and one of the dimensions of space


might be generated out of the peculiar interactions of
particles and fields existing in a lower-dimensional realm

planetary science
Did Life Come from Another World?

New research indicates that microorganisms could have


survived a journey from Mars to Earth

info tech, nanotech


Crossbar Nanocomputers

Crisscrossing assemblies of defect-prone nanowires could


succeed today's silicon-based circuits

earth science
The Workings of an Ancient Nuclear
Reactor

Two billion years ago parts of an African uranium deposit


spontaneously underwent nuclear fission. The details of this
remarkable phenomenon are just now becoming clear

neuroscience
The Neurobiology of the Self

Biologists are beginning to tease out how the brain gives rise
to a constant sense of being oneself

biotech
The Land of Milk and Money

The first drug from a transgenic animal may be nearing


approval

Working Knowledge: Case Cracked

Nuts

Oct 2005
astrophysics
Ripples in a Galactic Pond

Astronomers are coming to realize that the beautiful shapes


of galaxies are not merely incidental. They are essential to the
galaxies' growth and development

biotech
New Bull's-Eyes for Drugs

A familiar class of cell-surface receptors turns out to offer an


array of fresh targets that could yield new treatments for
disorders ranging from HIV to obesity

earth science
A Cool Early Earth?

The textbook view that the earth spent its first half a billion
years drenched in magma could be wrong. The surface may
have cooled quickly--with oceans, nascent continents and the
opportunity for life to form much earlier

neuroscience
The Forgotten Era of Brain Chips

The work of Jose Delgado, a pioneering star in brainstimulation research four decades ago, goes largely
unacknowledged today. What happened?

innovations
Better Than a Dog

The search is on for a sensor that bests a canine at detecting


explosives

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genetics
Founder Mutations

A special class of genetic mutations that often cause human


disease is enabling scientists to trace the migration and
growth of specific human populations over thousands of
years

info tech
Smart Wi-Fi

Wireless access to the Internet via Wi-Fi is increasingly


popular, so the technology is being upgraded to ensure that
users get prompt, reliable service

Working Knowledge: Paving the Way

Roads

Technicalities: Heavy-Metal Sweat

Does an infrared sauna really detoxify the body?

Sep 2005
anthropology
The Climax of Humanity

Demographically and economically, our era is unique in


human history. Depending on how we manage the next few
decades, we could usher in environmental sustainability--or
collapse

anthropology
Human Population Grows Up

As we swell toward nine billion in the next half a century,


humanity will undergo historic changes in the balance
between young and old, rich and poor, urban and rural. Our
choices now and in years ahead will determine how well we
cope with our coming of age

anthropology
Can Extreme Poverty Be Eliminated?

Market economics and globalization are lifting the bulk of


humanity out of extreme poverty, but special measures are
needed to help the poorest of the poor

ecology
Sustaining the Variety of Life

A new understanding of how species become extinct suggests


how to preserve them--and at a cost that doesn't break the
bank

energy
More Profit with Less Carbon

Focusing on energy efficiency will do more than protect


Earth's climate--it will make businesses and consumers richer

agriculture
The Big Potential of Small Farms

With the help of affordable irrigation and access to markets,


farmers in the developing world can grow more food and
climb out of poverty

public health
Public Health in Transition

Chronic disorders such as heart disease and diabetes, once


common only in the industrial nations, are now sweeping the
rest of the globe. Meanwhile the threat of infectious diseases
still looms large. New public health priorities are urgently
needed

economics
Economics in a Full World

The global economy is now so large that society can no


longer safely pretend it operates within a limitless ecosystem.
Developing an economy that can be sustained within the
finite biosphere requires new ways of thinking

policy
How Should We Set Priorities?

The world faces no shortage of problems--or of good ideas to


solve them. Which should we tackle next? Even as leaders
converge on some answers, new markets are being set up to
preempt politics

Working Knowledge: Private and Cool

Smart glass

Aug 2005

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biotech
Test-Tube Teeth

More complicated than they look, teeth are actually tiny


organs. If tissue engineers can manufacture living
replacement teeth, they would blaze a trail for engineering
larger organs while leading dentistry into the age of
regenerative medicine

paleontology
The Early Evolution of Animals

Tiny fossils reveal that complex animal life is older than we


thought--by at least as much as 50 million years

cosmology
Is the Universe Out of Tune?

Like the discord of key instruments in a skillful orchestra


quietly playing the wrong piece, mysterious discrepancies
have arisen between theory and observations of the "music"
of the cosmic microwave background. Either the
measurements are wrong or the universe is stranger than we
thought

info tech
Morphware

Magnetic logic may usher in an era in which computing


devices can change instantly from one type of hardware to
another

medicine
Beating a Sudden Killer

When a young woman nearly died from a ruptured aneurysm,


the author and the woman's husband began searching for
ways to save other aneurysm patients from catastrophe

psychology
Mindful of Symbols

On the way to learning that one thing can represent another,


young children often conflate the real item and its symbol.
These errors show how difficult it is to start thinking
symbolically

innovations, nanotech
Nanobodies

Antibodies, often described as magic bullets, are actually


more like tanks: big, complicated and expensive. Tinier
"nanobodies," derived from camels and llamas, may be able
to infiltrate a wider range of diseases at lower cost. That is
the hope, at least, of one small start-up in Belgium

Working Knowledge: Ease the Grind

Ball bearings

Technicalities: Heavenly Music in Your


Hand

Portable satellite radio is a palmtop cornucopia of music

Jul 2005
planetary science
The Many Faces of Mars

One rover found an ancient desert; the other, a once watery


world. The Red Planet's diversity rivals Earth's

physics
The Mysteries of Mass

Physicists are hunting for an elusive particle that would


reveal the presence of a new kind of field that permeates all
of reality. Finding that Higgs field will give us a more
complete understanding about how the universe works

medicine
The Future of Stem Cells

A special report from Scientific American and Financial


Times

climate change
Can We Bury Global Warming?

Pumping carbon dioxide underground to avoid warming the


atmosphere is feasible, but only if several key challenges can
be met

paleontology
How Dinosaurs Grew So Large--and So

Overlooked clues to how fast the creatures grew and how


long they lived lurk in their bones

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Small
info tech
Shrinking Circuits with Water

Semiconductor manufacturers are giving their products a


dousing in the name of faster, smaller, cheaper

biotech
New Movement in Parkinson's

Recent genetic and cellular discoveries are among the


advances pointing to improved treatments for this
increasingly common disorder

archaeology
Simulating Ancient Societies

Computer modeling is helping unravel the archaeological


mysteries of the American Southwest

Working Knowledge: Make It Quick

Rapid prototyping

Jun 2005
biotech
Buying Time in Suspended Animation

An ability to put the human body on hold could safeguard the


critically injured or preserve donor organs for transport. Does
the power to reversibly stop our biological clocks already lie
within us?

cosmology
Inconstant Constants

Do the inner workings of nature change with time?

info tech
Conversational Computers

Efforts to make computers speak naturally will let machines


better communicate meaning

health
Obesity: An Overblown Epidemic?

A growing number of dissenting researchers accuse


government and medical authorities--as well as the media--of
misleading the public about the health consequences of rising
body weights

physics
Making Cold Antimatter

Low-energy atoms of antihydrogen will enable researchers to


test a fundamental property of the universe

archaeology
The Morning of the Modern Mind

Controversial discoveries suggest that the roots of our


vaunted intellect run far deeper than is commonly believed

policy
Doubt Is Their Product

Industry groups are fighting government regulation by


fomenting scientific uncertainty

Working Knowledge: Lean and Mean

Hybrid vehicles

Technicalities: The Multipath to Clarity

Receiving HDTV over the air takes luck and lots of patience

May 2005
neuroscience
His Brain, Her Brain

It turns out that male and female brains differ quite a bit in
architecture and activity. Research into these variations could
lead to sex-specific treatments for disorders such as
depression and schizophrenia

physics
Quantum Black Holes

Physicists could soon be creating black holes in the


laboratory

info tech
Neuromorphic Microchips

Compact, efficient electronics based on the brain's neural


system could yield implantable silicon retinas to restore
vision, as well as robotic eyes and other smart sensors

meteorology
A Bolt out of the Blue

New research shows that lightning is a surprisingly complex


and mystifying phenomenon

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medicine
Can Chlamydia Be Stopped?

Chlamydia is a rampant sexually transmitted disease, the


world's leading cause of preventable blindness and a possible
contributor to heart disease. Recent discoveries are
suggesting new ways to curtail its spread

planetary science
What Heated the Asteroids?

Collisions among asteroids in the early history of the solar


system may help explain why many of these rocky bodies
reached high temperatures

biotech
Molecular Treasure Hunt

A software tool elicits previously undiscovered gene or


protein pathways by combing through hundreds of thousands
of journal articles

Working Knowledge: Thin Is In

Slim TV

Apr 2005
info tech
Stopping Spam

What can be done to stanch the flood of junk e-mail


messages?

earth science
Probing the Geodynamo

Scientists have long wondered why the polarity of the earth's


magnetic field occasionally reverses. Recent studies of our
planet's churning interior are offering intriguing clues about
how the next reversal may begin

biotech, genetics
The Alternative Genome

The old axiom "one gene, one protein" no longer holds true.
The more complex an organism, the more likely it became
that way by extracting multiple protein meanings from
individual genes

policy
Shaping the Future

Scientific uncertainty often becomes an excuse to ignore


long-term problems, such as climate change. It doesn't have
to be so

psychology
How Animals Do Business

Humans and other animals share a heritage of economic


tendencies--including cooperation, repayment of favors and
resentment at being shortchanged

materials science
Low-Temperature Superconductivity Is
Warming Up

Magnesium diboride defies the once conventional wisdom


about what makes a good superconductor. It becomes
superconducting near the relativity warm temperature of 40
kelvins--which promises a variety of applications

innovations
A Toxin against Pain

For years, scientists have promised a new wave of drugs


derived from sea life. A recently approved analgesic that is a
synthetic version of a snail toxin has become one of the first
marine pharmaceuticals

Working Knowledge: Uniform Variety

Tennis balls

Technicalities: Hot Stuff

New thermal cameras show the world in infrared

Mar 2005
cosmology
Misconceptions about the Big Bang

Baffled by the expansion of the universe? You're not alone.


Even astronomers frequently get it wrong

climate change
How Did Humans First Alter Global
Climate?

A bold new hypothesis suggests that our ancestors' farming


practices kicked off global warming thousands of years
before we started burning coal and driving cars

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info tech
If Smallpox Strikes Portland

"EpiSims" unleashes virtual plagues in real cities to see how


social networks spread disease. That knowledge might help
stop epidemics

innovations
On the Road to Fuel-Cell Cars

Although fleets of fuel-cell prototypes are hitting the streets,


basic technical and market obstacles must be hurdled before
the clean, hydrogen-powered cars reach dealer showrooms

biotech
Taming Lupus

Teasing out the causes of this autoimmune disorder is a


daunting challenge. But the payoff should be better, more
specific treatments

biography
Inventor of Dreams

Nikola Tesla, the father of today's AC electrical system and


other key inventions, often failed to bring his visionary ideas
to real-world fruition

ecology
Endangered Wild Equids

Wild zebra, asses and horses are being killed for meat,
medicine and money. Combined with vanishing habitats and
naturally slow reproduction, such predation threatens
remaining populations

Working Knowledge: Take My Pixel

Digital photography

Feb 2005
biotech
An Endangered Species in the Stomach

Is the decline of Helicobacter pylori, a bacterium living in the


human stomach since time immemorial, good or bad for
public health?

physics
Atom Chips

Magnetic fields on a microchip can produce tiny, coherent


clouds of atoms called Bose-Einstein condensates. The chips
could have uses n ultraprecise sensors for aircraft and in
quantum computing

anthropology
The Littlest Human

A spectacular find in Indonesia reveals that a strikingly


different hominid shared the earth with our kind in the not so
distant past

info science
Seeking Better Web Searches

Deluged with superfluous responses to online queries, users


will soon benefit from improved search engines that deliver
customized results

neuroscience
Making Memories Stick

Some moments become lasting recollections while others just


evaporate. The reason may involve the same processes that
shape our brains to begin with

innovations, nanotech
Nanotubes in the Clean Room

Talismans of a thousand graduate projects may soon make


their way into electronic memories

technology
The New College Try

Innovation is alive and kicking on campus

Working Knowledge: Reducing a Roar

Noise-canceling headphones

Technicalities: Every Breath You Take

Now a high-tech shirt can record your vital signs all day and
night

Jan 2005

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life science
Immunity's Early-Warning System

The innate immune response constitutes the first line of


defense against invading microbes and plays a role in
inflammatory disease. Surprising insights into how this system
operates could lead to new therapies for a host of infectious
and immune-related disorders

astrophysics
The Midlife Crisis of the Cosmos

Although it is not as active as it used to be, the universe is


still forming stars and building black holes at an impressive
pace

info science
Considerate Computing

Digital gadgets demand ever more of our attention with their


rude and thoughtless interruptions. Engineers are now testing
computers, phones and cars that sense when you're busy and
spare you from distraction

biotech
Capturing a Killer Flu Virus

The deadliest flu strain in history has been resurrected. What


can the 1918 virus reveal about why it killed millions and
where more like it may be lurking?

gallery
Eye of the Beholder

Wonders under the lens of the optical microscope

innovations, cryptography
Best-Kept Secrets

Quantum cryptography has marched from theory to


laboratory to real products

psychology
Exploding the Self-Esteem Myth

Boosting people's sense of self-worth has become a national


preoccupation. Yet surprisingly, research shows that such
efforts are of little value in fostering academic progress or
preventing undesirable behavior

Working Knowledge: Open Sesame

Keyless entry

Dec 2004
tech leaders
The Scientific American 50

Our third annual salute to the people and institutions


brightening our future recognizes accomplishments in stem
cells, nanocomputers, mini fuel cells and more

medicine
The Brain's Own Marijuana

Research into natural chemicals that mimic marijuana's


effects in the brain could help to explain--and suggest
treatments for--pain, anxiety, eating disorders, phobias and
other conditions

science and art


Optics and Realism in Renaissance Art

A much publicized assertion holds that 15th-century painters


achieved a new level of realism with the help of lenses and
mirrors. But recent findings cast doubt on that idea

paleontology
The Dinosaurs of Arctic Alaska

Seventy-five million years ago, a group of hardy dinosaurs


thrived in the harsh climate of what is now northern Alaska

astronomy
The Case of the Pilfered Planet

Did the British steal Neptune?

biology
Are Viruses Alive?

Although viruses challenge our concept of what "living"


means, they are vital members of the web of life

Working Knowledge: Crowded Skies

Air traffic control

Technicalities: More Than Just Music

Accessories can enhance the iPod music player

Nov 2004

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biotech
Rebuilding Broken Hearts

Biologists and engineers working together in the fledgling


field of tissue engineering are within reach of one of their
greatest goals: constructing a living human heart patch

physics
Black Hole Computers

In keeping with the spirit of the age, researchers can think of


the laws of physics as computer programs and the universe as
a computer

climate change
Abrupt Climate Change

Winter temperatures plummeting six degrees Celsius and


sudden droughts scorching farmland around the globe are not
just the stuff of scary movies. Such striking climate jumps
have happened before--sometimes within a matter of years

defense
Holes in the Missile Shield

The national missile defense now being deployed by the U.S.


should be replaced with a more effective system

info tech
Computing at the Speed of Light

Emerging ways to make photonic connections to electronic


microchips may dramatically change the shape of computers
in the decade ahead

neuroscience
Music and the Brain

What is the secret of music's strange power? Seeking an


answer, scientists are piecing together a picture of what
happens in the brains of listeners and musicians

innovations
A Split at the Core

Physics is forcing the microchip industry to redesign its most


lucrative products. That is bad news for software companies

Working Knowledge: Keep the Beat

Pacemakers

Oct 2004
astrophysics
A Universe of Disks

New research reveals the dynamics of the spinning disks of


gas that surround young stars and gargantuan black holes

molecular biology
The Hidden Genetic Program of
Complex Organisms

Biologists assumed that proteins alone regulate the genes of


humans and other complex organisms. But an overlooked
regulatory system based on RNA may hold the keys to
development and evolution

meteorology
Controlling Hurricanes

Can hurricanes and other severe tropical storms be


moderated or deflected?

info tech
The Internet of Things

The principles that gave rise to the Internet are now leading
to a new kind of network of everyday devices, an
"Internet-0"

physiology
Dying to See

Studies of the lens of the eye not only could reveal ways to
prevent cataracts but also might illuminate the biology of
Alzheimer's, Parkinson's and other diseases in which cells
commit suicide

policy
Fixing the Vote

Electronic voting machines promise to make elections more


accurate than ever before, but only if certain problems--with
the machines and the wider electoral process--are rectified

biotech
Hitting the Genetic Off Switch

A host of start-ups is speeding development of a new class of


drugs that block the action of RNA

Working Knowledge: Shock Absorbed

Earthquake protection

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Technicalities: Gadget Envy

http://www.davelo.net/sciam/regular-index.html

All-in-one cell phones can do just about anything

Sep 2004
physics
The Patent Clerk's Legacy

In 1905 the musings of a functionary in the Swiss patent


office changed the world forever. His intellectual bequest
remains for a new generation of physicists vying to concoct a
theory of everything

consumer electronics
Everyday Einstein

Finding your way out of the woods with GPS? Hanging a


picture frame with a laser level? Making photocopies? Better
thank Einstein

technology
Atomic Spin-offs for the 21st Century

A new generation of technologies aims to put Einstein's


theories to work in computers, hospitals - even submarines

physics
Einstein's Compass

What was it about the magnetism of an iron bar that could


divert Einstein from perfecting his celebrated theory of
general relativity?

physics
A Cosmic Conundrum

A new incarnation of Einstein's cosmological constant may


point the way beyond general relativity

physics
The String Theory Landscape

The theory of strings predicts that the universe might occupy


one random "valley" out of a virtually infinite selection of
valleys in a vast landscape of possibilities

physics
Was Einstein Right?

Unlike nearly all his contemporaries, Albert Einstein thought


quantum mechanics would give way to a classical theory.
Some researchers nowadays are inclined to agree

physics
The Search for Relativity Violations

To uncover evidence for an ultimate theory, scientists are


looking for infractions of Einstein's once sacrosanct physical
principle

physics
A Century of Einstein

Scientific American has covered Einstein's theories - and the


refinements and reactions to them - ever since scientists
began to grasp the import of his landmark 1905 papers. Read
on for a sampling of our reports, some by leading physicists
of their times

Working Knowledge: String Theory

Yo-yo

Aug 2004
biotech
Back to the Future of Cereals

Genomic studies of the world's major grain crops, together


with a technology called marker-assisted breeding, could
yield a new green revolution

space science
Electrodynamic Tethers in Space

By exploiting fundamental physical laws, tethers may provide


low-cost eletrical power, drag, thrust, and artificial gravity for
spaceflight

medicine
Virtual-Reality Therapy

Patients can get relief from pain or overcome their phobias by


immersing themselves in computer-generated worlds

weaponry
Nuclear Bunker Buster Bombs

New burrowing nuclear weapons could destroy subterranean


military facilities - but their strategic and tactical utility is
questionable

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info tech
Next Stretch for Plastic Electronics

Organic semiconductor devices can make more than just


bendable displays. They will find use in wearable electronics,
chemical sensors, skin for robots and innumerable other
applications

cosmology
Questions That Plague Physics

Lawrence M. Krauss speaks about unfinished business

public health
Arsenic Crisis in Bangladesh

Arsenic in drinking water could severly poison 50 million


people worldwide. Strategies being tested in Bangladesh
might help prevent the problem

Working Knowledge: Seeing Inside

Medical imaging

Technicalities: Crippled but Not Crashed Neural networks can help pilots land damaged planes
Jul 2004
astronomy
The Extraordinary Deaths of Ordinary
Stars

The demise of the sun in five billion years will be a


spectacular sight. Like other stars of its ilk, the sun will unfurl
into nature's premier work of art: a planetary nebula

genetics
Gene Doping

Gene therapy for restoring muscle lost to age or disease is


poised to enter the clinic, but elite athletes are eyeing it to
enhance performance. Can it be long before gene doping
changes the nature of sport?

info tech, nanotech


Magnetic Field Nanosensors

Tiny devices that take advantage of a recently discovered


physical effect called extraordinary magnetoresistance could
be used in blazingly fast computer disk drives with huge
capacities and in dozens of other applications involving the
sensing of magnetic fields

earth science
When Methane Made Climate

Today methane-producing microbes are confined to


oxygen-free settings, such as the guts of cows, but in Earth's
distant past, they ruled the world

biotech
Detecting Mad Cow Disease

New tests can rapidly identify the presence of dangerous


prions - the agents responsible for the malady - and several
compounds offer hope for treatment

mathematics
The Shapes of Space

A Russian mathematician has proved the century-old


Poincar conjecture and completed the catalogue of threedimensional spaces. He might earn a $1-million prize

cryptography
The Mystery of the Voynich Manuscript

New analysis of a famously cryptic medieval document


suggests that it contains nothing but gibberish

Working Knowledge: Big Air

Pipe organs

Jun 2004
planetary science
Saturn at Last!

After a seven-year journey, the Cassini-Huygens spacecraft is


preparing to unveil the mysteries of Saturn, its rings and its
giant moon, Titan

nanotech
Nanotechnology and the Double Helix

DNA is more than just the secret of life - it is also a versatile


component for making nanoscopic structures and devices

ecology
Lessons from the Wolf

Bringing the top predator back to Yellowstone has triggered a


cascade of unanticipated changes in the park's ecosystem

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info tech
Smart Sensors to Network the World

An emerging class of pillbox-size computers, outfitted with


sensors and linked together by radios, can form perceptive
networks able to monitor a factory, a store - even an
ecosystem. Such devices will more intimately connect the
cyberworld to the real world

biotech
The Stem Cell Challenge

What hurdles stand between the promise of human stem cell


therapies and real treatments in the clinic?

weaponry
Nuclear Explosions in Orbit

The spread of nuclear weapons and ballistic missiles raises


fears of atomic attacks on the global satellite system

Technicalities: Security at Your


Fingertips

Fingerprint sensors can guard your computer data

May 2004
cosmology
The Myth of the Beginning of Time

String theory suggests that the big bang was not the origin of
the universe but simply the outcome of a preexisting state

energy
Questions about a Hydrogen Economy

Much excitement surrounds the progress in fuel cells, but the


quest for a hydrogen economy is no trivial pursuit

biotech
Synthetic Life

Biologists are crafting libraries of interchangeable DNA parts


and assembling them inside microbes to create
programmable, living machines

neuroscience
Freud Returns

Neuroscientists are finding that their biological descriptions


of the brain may fit together best when integrated by
psychological theories Freud sketched a century ago. Also:
Counterpoint from J. Allan Hobson, who argues that Freud's
thinking is still highly suspect

From hikers navigating with handheld locators to pilots


landing in zero-visibility conditions, the Global Positioning
info tech
Retooling the Global Positioning System System now serves more than 30 million users. See what's
coming next
planetary science
The Transit of Venus

When Venus crosses the face of the sun this June, scientists
will celebrate one of the greatest stories in the history of
astonomy

Working Knowledge: Clear Favorite

Laser eye surgery

Puzzling Adventures: Jump Snatch

Jumping to a conclusion

Apr 2004
neuroscience
The Other Half of the Brain

Mounting evidence suggests that glial cells, overlooked for


half a century, may be nearly as critical to thinking and
learning as neurons are

planetary science
The Hidden Members of Planetary
Systems

The solar system consists of more than just planets; it is also a


beehive of asteroids and comets. Is that the case for other
planetary systems, too?

psychology
The Tyranny of Choice

Logic suggests that having options allows people to select


precisely what makes them happiest. But, as studies show,
abundant choice often makes for misery

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info tech
The First Nanochips

As scientists and engineers continue to push back the limits of


chipmaking technology, they have quietly entered into the
nanometer realm

biotech
Evolution Encoded

New discoveries about the rules governing how genes encode


proteins have revealed nature's sophisticated "programming"
for protecting life from catastrophic errors while accelerating
evolution

space science
Blastoffs on a Budget

Private ventures seeking to make routine access to space


affordable see big potential in going small

Working Knowledge: Complete Burn

Fuel injection

Technicalities: Plug-and-Play Robots

Personal robots may soon be as cheap and customizable as


personal computers

Puzzling Adventures: Bluffhead

The game of Bluffhead

Mar 2004
planetary science
The Spirit of Exploration

NASA's rover fights the curse of the Angry Red Planet

info tech, robotics


A New Race of Robots

Around the U.S., engineers are finishing one-year crash


projects to create robots able to dash 200 miles through the
Mojave Desert in a day, unaided by humans. Scientific
American tailed the odds-on favorite team for 10 months and
found that major innovations in robotics are not enough to
win such a contest. Obsession is also required

climate change
Defusing the Global Warming Time
Bomb

Global warming is real, and the consequences are potentially


disastrous. Nevertheless, practical actions, which would also
yield a cleaner, healthier atmosphere, could slow, and
eventually stop, the process

biotech
The Addicted Brain

Drug abuse produces long-term changes in the reward


circuitry of the brain. Knowledge of the cellular and
molecular details of these adaptations could lead to new
treatments for the compulsive behaviors that underlie
addiction

earth science
The Threat of Silent Earthquakes

A lack of rumbling does not necessarily make an earthquake


harmless. Some of the quiet types could presage devasting
tsunamis or larger, ground-shaking shocks

science and society


The Fairest Vote of All

All voting systems have drawbacks. But by taking into


account how voters rank candidates, one system gives the
truest reflection of the electorate's views

Working Knowledge: Rock Clock

Quartz watches

Puzzling Adventures: Grid Speed

Traffic on the grid

Feb 2004
biotech
Insights into Shock

Still a last step before death for thousands of people, shock is


shedding some of it medical mystery and becoming more
treatable

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cosmology
The Cosmic Symphony

New observations of the cosmic microwave background


radiation show that the early universe resounded with
harmonious oscillations

cosmology
Reading the Blueprints of Creation

The latest maps of the cosmos have surveyed hundreds of


thousands of galaxies, whose clustering has grown from
primordial fluctuations

cosmology
From Slowdown to Speedup

Distant supernovae are revealing the crucial time when the


expansion of the universe changed from decelerating to
accelerating

cosmology
Out of the Darkness

Maybe cosmic acceleration isn't caused by dark energy after


all but by an inexorable leakage of gravity out of our world

info tech
Better Displays with Organic Films

Light-emitting organic materials offer brighter and more


efficient displays than LEDs. An you'll be able to unroll them
across a tabletop

criminology
The Case of the Unsolved Crime
Decline

Criminologists have not yet cracked the case, but they now
know more about why U.S. crime rates plummeted in the
1990s - and how to help keep them down

Working Knowledge: Data Driven

Automobile black box

Technicalities: A Walk in the Woods

Satellites show the way in the new sport of geocaching

Puzzling Adventures: All or Nothing

Numerical messages

Jan 2004
astronomy
Our Growing, Breathing Galaxy

Long assumed to be a relic of the distant past, the Milky Way


turns out to be a dynamic, living object

neuroscience
Decoding Schizophrenia

A fuller understanding of signaling in the brain of people with


this disorder offers new hope for improved therapy

Already common in security systems and tollbooths, radioinfo tech


frequency identification tags and readers stand poised to take
RFID: A Key to Automating Everything
over many processes now accomplished by human toil
physics
Atoms of Space and Time

We perceive space and time to be continuous, but if the


amazing theory of loop quantum gravity is correct, they
actually come in discrete pieces

archaeology
Women and Men at atalhyk

The largest known Neolithic settlement yields clues about the


roles played by the two sexes in early agricultural societies

environment
Spring Forward

As temperatures rise sooner in spring, interdependent species


in many ecosystems are shifting dangerously out of sync

mathematics
The Curious History of the First Pocket
Calculator

It was called the Curta, and it proved lifesaving when its


inventor was trapped in a Nazi concentration camp

Working Knowledge: Phantom Gain

Virtual 1st down marker

Puzzling Adventures: Verifying Your


Circuits

Verifying circuits

Dec 2003

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tech leaders
The Scientific American 50

Our second annual salute to the elite of research, industry and


politics whose accomplishments are shaping a better, wiser
technological future for the world

biology
Does Race Exist?

If races are defined as genetically discrete groups, no. But


researchers can use some genetic information to group
individuals into clusters with medical relevance

planetary science
The New Moon

Recent lunar missions have shown that there is still much to


learn about Earth's closest neighbor

aviation
The Equivocal Success of the Wright
Brothers

The Wrights used aerial control as the key to building and


flying the first airplane. But trying to refine their invention in
secret nearly cost them their glory

earth science
The Day the World Burned

The dinosaur-killing impact set off a wave of wildfires that


consumed Earth's forests

biotech
The Unseen Genome: Beyond DNA

DNA was once considered the sole repository of heritable


information. But biologists are starting to decipher a separate,
much more malleable layer of information encoded within the
chromosomes. Genetics, make way for epigenetics

Working Knowledge: At the Moment

Electronic skis

Technicalities: Science for Cops

A behind-the-scenes look at a high-tech police lab

Puzzling Adventures: You Don't Say!

Parallel repetition

Nov 2003
biotech
The Unseen Genome: Gems among the
Junk

Just when scientists thought they had DNA almost figured


out, they are discovering in chromosomes two vast, but
largely hidden, layers of information that affect inheritance,
development and disease

space science
The Asteroid Tugboat

To prevent an asteroid from hitting Earth, a space tug


equipped with plasma engines could give it a push

robotics
An Army of Small Robots

For robot designers these days, small is beautiful

physics
The Future of String Theory - A
Conversation with Brian Greene

The physicist and best-selling author demystifies the ultimate


theories of space and time, the nature of genius, multiple
universes, and more

evolution
Stranger in a New Land

Stunning finds in the Republic of Georgia upend


long-standing ideas about the first hominids to journey out of
Africa

aviation
Flying on Flexible Wings

Future aircraft may fly more like birds, adapting geometrics


of their wings to best suit changing flight conditions

neuroscience
Why We Sleep

The reasons that we sleep are gradually becoming less


enigmatic

Working Knowledge: Staying Power

Nails and staples

Puzzling Adventures: Liquid


Switchboard

Liquid switchboard

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Oct 2003
astronomy
The Unexpected Youth of Globular
Clusters

Conventional wisdom says that globular star clusters are the


stodgy old codgers of the universe, but it turns out that many
of these clusters are young

materials science
Artificial Muscles

Novel motion-producing devices - actuators, motors,


generators - based on polymers that change shape when
stimulated electrically are nearing commercialization

environment
Meltdown in the North

Sea ice and glaciers are melting, permafrost is thawing, tundra


is yielding to shrubs - and scientists are struggling to
understand how these changes will affect not just the Arctic
but the entire planet

biotech
Tumor-Busting Viruses

A new technique called virotherapy harnesses viruses, those


banes of humankind, to stop another scourge--cancer

space science
China's Great Leap Upward

By boosting astronauts into orbit, China hopes to become the


newest superpower in space

economics
The Economics of Child Labor

Campaigns against child labor are most likely to succeed


when they combine the long arm of the law with the invisible
hand of the marketplace

Working Knowledge: Cool Shirt

Smart fabrics

Technicalities: The Infinite Arcade


Machine

Building the world's largest video arcade - in your family


room

Puzzling Adventures: Strategic Bullying

Strategic bullying

Sep 2003
neuroscience
Brain, Repair Yourself

How do you fix a broken brain? The answers may literally lie
within our heads. The same approaches might also boost the
power of an already healthy brain

neuroscience
The Quest for a Smart Pill

New drugs to improve memory and cognitive performance in


impaired individuals are under intensive study. Their possible
use in healthy people already triggers debate

neuroscience
Stimulating the Brain

Activating the brain's circuitry with pulsed magnetic fields


may help ease depression, enhance cognition, even fight
fatigue

neuroscience
Mind Readers

Brain-scanning machines may soon be capable of discerning


rudimentary thoughts and separating fact from fiction

neuroscience
The Mutable Brain

Score one for believers in the adage "use it or lose it."


Targeted mental and physical exercises seem to improve the
brain in unexpected ways

neuroscience
Taming Stress

An emerging understanding of the brain's stress pathways


points toward treatments for anxiety and depression beyond
Valium and Prozac

neuroscience
Diagnosing Disorders

Psychiatric illnesses are often hard to recognize, but genetic


testing and neuroimaging could someday be used to improve
detection

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Working Knowledge: On the Money

Bill validators

Puzzling Adventures: Missing Hiker

Find the missing hiker

Aug 2003
biotech
Censors of the Genome

Biologists have been surprised to discover that most animal


and plant cells contain a built-in system to silence individual
genes by shredding the RNA they produce. Biotech
companies are already working to exploit it

info tech
Demystifying the Digital Divide

The simple binary notion of technology haves and have-nots


doesn't quite compute

neuroscience
Rethinking the "Lesser Brain"

Long thought to be solely the brain's coordinator of body


movement, the cerebellum is now known to be active during
a wide variety of cognitive and perceptual activities

Theoretical results about black holes suggest that the universe


physics
Information in the Holographic Universe could be like a gigantic hologram
archaeology
Questioning the Delphic Oracle

When science meets religion at this ancient Greek site, the


two turn out to be on better terms than scholars had originally
thought

evolution
Planet of the Apes

During the Miocene epoch, as many as 100 species of apes


roamed throughout the Old World. New fossils suggest that
the ones that gave rise to living great apes and humans
evolved not in Africa but Eurasia

Working Knowledge: Seeing Green

Night vision

Technicalities: Converging on the Couch

New devices connect the stereo and TV to the home data


network

Puzzling Adventures: Short Taps

Outwitting spies

Jul 2003
astronomy
The Galactic Odd Couple

Why do giant black holes and stellar baby booms, two


phenomena with little in common, so often go together?

environment
Counting the Last Fish

Overfishing has slashed stocks - especially of large predator


species - to an all-time low worldwide, according to new data.
If we don't manage this resource, we will be left with a diet of
jellyfish and plankton stew

info tech
Antennas Get Smart

Adaptive antenna arrays can vastly improve wireless


communications by connecting mobile users with virtual
wires

biotech
Untangling the Roots of Cancer

Recent evidence challenges long-held theories of how cells


turn malignant - and suggests new ways to stop tumors before
they spread

archaeology
Uncovering the Keys to the Lost Indus
Cities

Recently excavated artifacts from Pakistan have inspired a


reevaluation of one of the great early urban cultures - the
enigmatic Indus Valley civilization

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medicine
Pumphead

In what has become almost routine, the heart-lung machine


"breathes" for patients during coronary-bypass operations.
But could this lifesaving device have a dark side?

Insights: Terms of Engagement

Irving Weissman directs a new institute dedicated to the


cloning of human embryonic stem cells. Just don't call it
cloning

Working Knowledge: Fine Focus

Scanning electron microscopes

Puzzling Adventures: High Spies

Tracking contraband shipments

Jun 2003
medicine
Shoot This Deer

Chronic wasting disease, a cousin of mad cow disease, is


spreading among wild deer in parts of the U.S. Left
unchecked, the fatal sickness could threaten North American
deer populations - and maybe livestock and humans

astronomy
The Unearthly Landscapes of Mars

The Red Planet is no dead planet

computing
Self-Repairing Computers

By embracing the inevitability of system failures, recoveryoriented computing returns service faster

biotech
Pandora's Baby

In vitro fertilization was once considered by some to be a


threat to our very humanity. Cloning inspires similar fears

physics
The Dawn of Physics Beyond the
Standard Model

The Standard Model of particle physics is at a pivotal


moment in its history: it is both at the height of its success
and on the verge of being surpassed

info science
Chain Letters and Evolutionary
Histories

A study of chain letters shows how to infer the family tree of


anything that evolves over time, from biological genomes to
languages to plagiarized schoolwork

May 2003
cosmology
Parallel Universes

Not just a staple of science fiction, other universes are a


direct implication of cosmological observations

neuroscience
Hearing Colors, Tasting Shapes

People with synesthesia - whose senses blend together - are


providing valuable clues to understanding the organization
and functions of the human brain

info tech
Scale-Free Networks

Scientists have recently discovered that various complex


systems have an underlying architecture governed by shared
organizing principles. This insight has important implications
for a host of applications, from drug development to Internet
security

archaeology
The Iceman Reconsidered

Where was the Iceman's home and what was he doing at the
high mountain pass where he died? Painstaking research especially of plant remains found with the body - contradicts
many of the initial speculations

biotech
The Orphan Drug Backlash

The Orphan Drug Act of 1983 was supposed to provide


incentives for private industry to develop needed, but
unprofitable, drugs to treat rare diseases. It has done so, but
not without eliciting controversy

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Working Knowledge: Catch a Wave

Antennas

Puzzling Adventures: Bounded Regrets

Competitive analysis and the regret ratio

Apr 2003
astrophysics
Solving the Solar Neutrino Problem

The Sudbury Neutrino Observatory has solved a 30-year-old


mystery by showing that neutrinos from the sun change
species en route to the earth

biotech
Where a Pill Won't Reach

How to get drugs where they need to go

earth science
Mount Etna's Ferocious Future

Europe's biggest and most active volcano is growing more


dangerous. Luckily, the transformation is happening slowly

genetics
A Conversation with James D. Watson

The co-discoverer of DNA's double helix reflects on the


molecular model that changed both science and society

life science
Questioning the Oldest Signs of Life

In the past year scientists have been forced to reconsider how


they identify life in the most ancient rocks on earth - and
elsewhere in the solar system

info tech
The Grid: Computing without Bounds

By linking digital processors, storage systems and software on


a global scale, grid technology is poised to transform
computing from an individual and corporate activity into a
general utility

medicine
The Lowdown on Ginkgo Biloba

This popular herbal supplement may slightly improve your


memory, but you can get the same effect by eating a candy
bar

Working Knowledge: Potent Patches

Transdermal drug delivery

Technicalities: Screen Writing

The tablet PC is a high-tech tool for scribblers

Puzzling Adventures: The Graph of Life Graphing the origins of species


Mar 2003
physics
The Search for Dark Matter

Dark matter is usually thought of as something "out there."


But we will never truly understand it unless we can bring it
down to earth

energy, environment
Dismantling Nuclear Reactors

Taking apart a nuclear power plant that has reached the end
of its life is a complicated task. But not for the reasons you
might expect

biotech
Restoring Aging Bones

The bone decay of osteoporosis can cripple, but an improved


understanding of how the body builds and loses bone is
leading to ever better prevention and treatment options

info tech
Digital Entertainment Jumps the Border

New broadcasting technologies are challenging the


restrictions on the viewing of American television shows and
films in other countries

evolution
Which Came First, the Feather or the
Bird?

A long-cherished view of how and why feathers evolved has


now been overturned

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neuroscience
Bugs in the Brain

Time for a bit of humility. Some microorganisms can


manipulate neural circuitry better than we can

Working Knowledge: No Two Alike

Fingerprint readers

Puzzling Adventures: Safecracking

The safecracker's strategy

Feb 2003
astrophysics
Magnetars

Some stars are magnetized so intensely that they emit huge


bursts of magnetic energy and alter the very nature of the
quantum vacuum

neuroscience
Why? The Neuroscience of Suicide

New research addresses the wrenching question left when


someone ends his or her own life

info tech
Evolving Inventions

Computer programs that function via Darwinian evolution are


creating inventions that are novel and useful enough to be
patented

environment
Explaining Frog Deformities

An eight-year investigation into the cause of a shocking


increase in deformed amphibians has sorted out the roles of
three prime suspects

weaponry
Satellite-Guided Munitions

Highly accurate yet affordable strike weapons, proved in


Afghanistan, are the latest upgrades to America's arsenal

medicine
Drink to Your Health?

Three decades of research shows that drinking small to


moderate amounts of alcohol has cardiovascular benefits. A
thorny issue for physicians is whether to recommend drinking
to some patients

Working Knowledge: Carbon Copy

Synthetic diamonds

Technicalities: Robots That Suck

Have they finally come out with a robot for the rest of us?

Puzzling Adventures: Five Trusty Flares

Choosing trustworthy flares

Jan 2003
medicine
New Light on Medicine

Pigments that turn caustic on exposure to light can fight


cancer, blindness and heart disease. Their light-induced
toxicity may also help explain the origin of vampire tales

info tech, nanotech


The Nanodrive Project

Inventing a nanotechnology device for mass production and


consumer use is trickier than it sounds

paleontology
An Ancestor to Call Our Own

Controversial new fossils could bring scientists closer than


ever to the origin of humanity

nutrition
Rebuilding the Food Pyramid

The dietary guide introduced a decade ago has led people


astray. Some fats are healthy for the heart, and many
carbohydrates clearly are not

earth science
Earthquake Conversations

Contrary to prevailing wisdom, large earthquakes can interact


in unexpected ways. This exciting discovery could
dramatically improve scientists' ability to pinpoint future
shocks

physics
The Science of Bubbly

Scientists study the nose-tickling effervescence of champagne


- an alluring and unmistakable aspect of its appeal

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Working Knowledge: Scratch Match

Ballistics

Puzzling Adventures: Protein Chime

Timing with proteins

Dec 2002
tech leaders
The Scientific American 50

Our first annual celebration of visionaries from the worlds of


research, industry and politics whose recent accomplishments
point toward a brighter technological future for everyone

astronomy
The Brightest Explosions in the
Universe

Every time a gamma-ray burst goes off, a black hole is born

biotech
The Enigma of Huntington's Disease

Nearly 10 years after scientists isolated the gene responsible


for Huntington's, they are still searching for how it wreaks its
devastation

climate change
On Thin Ice

How soon humanity will have to move inland to escape rising


seas depends in great part on how quickly West Antarctica's
massive ice sheet shrinks. Scientists are finally beginning to
agree on what controls the size of the sheet and its rate of
disintegration

evolution
Food for Thought

Dietary change was a driving force in human evolution

info tech
Order in Pollock's Chaos

Computer analysis is helping to explain the appeal of Jackson


Pollock's paintings. The artist's famous drips and swirls create
fractal patterns, similar to those formed in nature by trees,
clouds and coastlines

Working Knowledge: Superhot Dots

Ink-jet printing

Technicalities: Getting Real

What's next in computer displays? Depth and shadows

Puzzling Adventures: Plumbers

Find the blabbermouth

Nov 2002
astronomy
When Stars Collide

When two stars smash into each other, it can be a very pretty
sight (as long as you're not too close by). These occurrences
were once considered impossible, but they have turned out to
be common in certain galactic neighborhoods

biotech
The Long Arm of the Immune System

Dendritic cells catch invaders and tell the immune system


when and how to respond. Vaccines depend on them, and
scientists are even employing the cells to stir up immunity
against cancer

zoology
Gladiators: A New Order of Insect

A mystery in amber is solved on a desert mountain with a


discovery that has stunned entomologists

info tech
Rules for a Complex Quantum World

An exciting new fundamental discipline of research combines


information science and quantum mechanics

defense
Weapons of Mass Disruption

Radiological terror weapons could blow radioactive dust


through cities, causing panic, boosting cancer rates and
forcing costly cleanups

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environment
Burning Questions

Scientists work to understand and control the plague of


wildfires in the West

Working Knowledge: See the Wind

Weather radar

Puzzling Adventures: Perfect Billiards

Perfect billiards: working the angles

Oct 2002
robotics
Controlling Robots with the Mind

People with nerve or limb injuries may one day be able to


command wheelchairs, prosthetics and even paralyzed arms
and legs by "thinking them through" the motions

astronomy
The Emptiest Places

Space comes in degrees of emptiness, but even in the


wasteland between galaxies it is not a complete void

technology
Vehicle of Change

Hydrogen fuel-cell cars could be the catalyst for a cleaner


tomorrow

biology
Skin Deep

Throughout the world, human skin color has evolved to be


dark enough to prevent sunlight from destroying the nutrient
folate but light enough to foster the production of vitamin D

defense
Technology against Terror

Biologists and engineers are devising early-warning systems


that can detect a bioterrorist attack in time to blunt its effects

info tech
Lightning Rods for Nanoelectronics

Electrostatic discharges threaten to halt further shrinking and


acceleration of electronic devices in the future

Working Knowledge: Vying for Eyes

Flat displays

Technicalities: Computers for the Third


World

The Simputer is a handheld device designed for rural villagers

Puzzling Adventures: Prime Spies

Prime spies

Sep 2002
physics
Real Time

The pace of living quickens continuously, yet a full


understanding of things temporal still eludes us

physics
That Mysterious Flow

From the fixed past to the tangible present to the undecided


future, it feels as though time flows inexorably on. But that is
an illusion

physics
A Hole at the Heart of Physics

Physicists can't seem to find the time - literally. Can


philosophers help?

physics
How to Build a Time Machine

It wouldn't be easy, but it might be possible

physics
From Instantaneous to Eternal

The units of time range from the infinitesimally brief to the


interminably long. The descriptions given here attempt to
convey a sense of this vast chronological span

physics
Times of Our Lives

Whether they're counting minutes, months or years,


biological clocks help keep our brains and bodies running on
schedule

neuroscience
Remembering When

Several brain structures contribute to "mind time," organizing


our experiences into chronologies of remembered events

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anthropology
Clocking Cultures

What is time? The answer varies from society to society

technology
A Chronicle of Timekeeping

Our conception of time depends on the way we measure it

technology
Ultimate Clocks

Atomic clocks are shrinking to microchip size, heading for


space - and approaching the limits of useful precision

Puzzling Adventures: Venture Bets

Investments and probabilities

Aug 2002
biotech
The Serious Search for an Anti-Aging
Pill

In government laboratories and elsewhere, scientists are


seeking a drug able to prolong life and youthful vigor. Studies
of caloric restriction are showing the way

cosmology
Does Dark Matter Really Exist?

Ninety-five percent of the universe has gone missing. Or has


it?

environment
The Ocean's Invisible Forest

Marine phytoplankton play a critical role in regulating the


earth's climate. Could they also be used to combat global
warming?

info tech
Computers without Clocks

Asynchronous chips improve computer performance by


letting each circuit run as fast as it can

psychology
Combating the Terror of Terrorism

The psychological damage caused by the attacks of


September 11 mirrored the physical destruction and showed
that protecting the public's mental health must be a
component of the national defense

linguistics
Saving Dying Languages

Linguists have known for years that thousands of the world's


languages are at grave risk of extinction. Yet only recently
has the field summoned the will - and the money - to do much
about it

Working Knowledge: Safety at a Cost

Smart cards

Technicalities: Machine Chic

The Poma wearable computer is flashy but not very


functional

Puzzling Adventures: Repellanoids

Repellanoid circumference

Jul 2002

biotech
Sweet Medicines

Sugars play critical roles in many cellular functions and in


disease. Study of those activities lags behind research into
genes and proteins but is beginning to heat up. The
discoveries promise to yield a new generation of drug
therapies

info tech
Last Mile by Laser

Short-range infrared lasers could beam advanced broadband


multimedia services directly into homes and offices

zoology
The Nose Takes a Starring Role

The star-nosed mole has what is very likely the world's fastest
and most fantastic nose

medicine
The Trials of an Artificial Heart

A year after doctors began implanting the AbioCor in dying


patients, the prospects of the device are uncertain

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physics
Uncovering Supersymmetry

A strange, elusive phenomenon called supersymmetry was


conceived for elementary particle physics - but has come to
light in nuclei of platinum and gold

evolution
15 Answers to Creationist Nonsense

Opponents of evolution want to make a place for creationism


by tearing down real science, but their arguments don't hold
up

Working Knowledge: Turn Turn Turn

Windmills

Puzzling Adventures: Blind Justice

Mathematical justice

Jun 2002
biotech
Hope in a Vial

Will there be an AIDS vaccine anytime soon?

cosmology
The Life Cycle of Galaxies

Astronomers are on the verge of explaining the enigmatic


variety of galaxies

zoology
Disturbing Behaviors of the Orangutan

Studies of these great apes show that some males pursue an


unexpected and disquieting evolutionary strategy

info tech
Spintronics

Microelectronic devices that function by using the spin of the


electron are a nascent multibillion-dollar industry - and may
lead to quantum microchips

psychology
Islands of Genius

Artistic brilliance and a dazzling memory can sometimes


accompany autism and other developmental disorders

chemistry
The Complexity of Coffee

One of life's simple pleasures is really quite complicated

medicine
No Truth to the Fountain of Youth

Fifty-one scientists who study aging have issued a warning to


the public: no anti-aging remedy on the market today has
been proved effective. Here's why they are speaking up

Working Knowledge: Hidden Guides

Gyroscope guidance

Technicalities: Whatever You Say

With speech-recognition software, your voice is the


computer's command

Puzzling Adventures: Privacy Taboos

Privacy among the Paranoimos

May 2002
biotech
Atherosclerosis: The New View

It causes chest pain, heart attack and stroke, leading to more


deaths every year than cancer. The long-held conception of
how the disease develops turns out to be wrong

planetary science
Journey to the Farthest Planet

Scientists are finally preparing to send a spacecraft to Pluto


and the Kuiper Belt, the last unexplored region in our
planetary system

info tech
Wireless Data Blaster

Radio's oldest technology is providing a new way for portable


electronics to transmit large quantities of data rapidly without
wires

New fossils and DNA analyses elucidate the remarkable


evolution
The Mammals That Conquered the Seas evolutionary history of whales

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physics
Extreme Light

Focusing light with the power of 1,000 Hoover Dams onto a


point the size of a cell nucleus accelerates electrons to the
speed of light in a femtosecond

environment
Rethinking Green Consumerism

Buying green products won't be enough to save biodiversity


in the tropics. A new plan for marketing conservation
services may be the answer

Puzzling Adventures: Defense in Depth

Avoiding tackles in a football game

Apr 2002
biotech
Proteins Rule

Proteomics is biotech's "new new thing." Its enthusiasts are


racing to catalogue the proteins in our bodies and to figure
out how they network with one another. These efforts could
lead to more and better drugs

info tech
Augmented Reality: A New Way of
Seeing

Computer scientists are developing systems that can enhance


and enrich a user's view of the world

zoology
Parasitic Sex Puppeteers

By directing its victims' sex lives, the bacterial parasite


Wolbachia may be helping to produce new species

physics
Ripples in Spacetime

Physicists have spent eight years and $365 million building a


radically new kind of observatory to detect gravitational
waves. But will it work? A trial run put it to the test

health
The Science of Bad Breath

The age-old condition of bad breath is coming under new


scientific scrutiny, leading to insights into diagnostic
approaches and possible solutions

psychology
The Social Psychology of Modern
Slavery

Contrary to conventional wisdom, slavery has not


disappeared from the world. Social scientists are trying to
explain its persistence

Puzzling Adventures: A Fairy Tale

A tale of fairies and pearls

Working Knowledge: Grow, Then Kill

Lab tests

Technicalities: Bringing the Net to the


Bedroom

Even an amateur can create a custom-designed internet


appliance

Mar 2002
info tech
The Worldwide Computer

An operating system spanning the Internet would bring the


power of millions of the world's Internet-connected PCs to
everyone's fingertips

biotech
Attacking Anthrax

Recent discoveries are suggesting much-needed strategies for


improving prevention and treatment. High on the list: ways to
neutralize the anthrax bacterium's fiendish toxin

astronomy
The Cosmic Reality Check

A celestial audit suggests that astronomers' inventory of


luminous bodies may soon be complete

psychology
Scars That Won't Heal: The
Neurobiology of Child Abuse

Maltreatment at an early age can have enduring negative


effects on a child's brain development and function

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earth science
Repeated Blows

Did extraterrestrial collisions capable of causing widespread


extinctions pound the earth not once, but twice - or even
several times?

education
How Should Reading be Taught?

Educators have long argued over the best way to teach


reading to children. The research, however, indicates that a
highly popular method is inadequate on its own

Working Knowledge: Secret of Spin

Combination locks

Puzzling Adventures: Card Counters

Card counting with Bob and Alice

Feb 2002
info tech
The Network in Every Room

Thanks to ingenious engineering, computers and appliances


can now communicate through the electrical wiring in a
house

biotech
The Magic of Microarrays

Research tools known as DNA microarrays are already


clarifying the molecular roots of health and disease and
speeding drug discovery. They could also hasten the day
when custom-tailored treatment plans replace a one-sizefits-all approach to health care

paleontology
Madagascar's Mesozoic Secrets

The world's fourth-largest island divulges fossils that could


revolutionize scientific views on the origins of dinosaurs and
mammals

astronomy
Bejeweled Worlds

What an impoverished universe it would be if Saturn and the


other giant planets lacked rings. Planetary scientists are
finally working out how gravity has sculpted these elegant
ornaments

psychology
Television Addiction

Understanding how closely compulsive TV viewing resembles


other forms of addiction may help couch potatoes control
their habit

environment
The Bottleneck

We have entered the Century of the Environment, in which


the immediate future is usefully conceived as a bottleneck:
science and technology, combined with foresight and moral
courage, must see us through it and out

Working Knowledge: Eye in the Sky

Aerial and satellite imaging

Technicalities: Surrounded by Sound

Ingenious software makes ordinary stereo speakers come


alive

Puzzling Adventures: Shifty Witnesses

Skipping the preliminaries, the detective stated his problem:


"We have five witnesses whom we don't trust. They have
trailed a group of 10 suspected drug dealers. For each
suspect, the five witnesses take a vote about whether the
suspect has drugs or not.

Jan 2002
astronomy
The Gas between the Stars

Filled with colossal fountains of hot gas and vast bubbles


blown by exploding stars, the interstellar medium is far more
interesting than scientists once thought

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biotech
The First Human Cloned Embryo

Cloned early-stage human embryos - and human embryos


generated only from eggs, in a process called parthenogenesis
- now put therapeutic cloning within reach

info tech
A Vertical Leap for Microchips

Engineers have discovered a way to pack more computing


power into microcircuits: build them vertically as well as
horizontally

environment
Misleading Math about the Earth

Science defends itself against The Skeptical Environmentalist

energy
Next-Generation Nuclear Power

New, safer and more economical nuclear reactors could not


only satisfy many of our future energy needs but could
combat global warming as well

psychology
The Economics of Fair Play

Why do we value fairness and cooperation over seemingly


more rational selfishness? How can Darwinian generosity
arise? Biologists and economists explain

Working Knowledge: Breathing Easier?

Gas masks

Puzzling Adventures: Pinpointing a


Polar Bear

How many hunters does it take to catch a polar bear?

Dec 2001
medicine
Vessels of Death or Life

Angiogenesis - the formation of new blood vessels - might


one day be manipulated to treat disorders from cancer to
heart disease. First-generation drugs are now in the final
phase of human testing

physics
Photonic Crystals: Semiconductors of
Light

Nanostructured materials containing ordered arrays of holes


could lead to an optoelectronics revolution, doing for light
what silicon did for electrons

evolution
How We Came to Be Human

The acquisition of language and the capacity for symbolic art


may lie at the very heart of the extraordinary cognitive
abilities that set us apart from the rest of creation

astronomy
The First Stars in the Universe

Exceptionally massive and bright, the earliest stars changed


the course of cosmic history

weaponry
India, Pakistan and the Bomb

The Indian subcontinent is the most likely place in the world


for a nuclear war

info tech
Origins of Personal Computing

Forget Gates, Jobs and Wozniak. The foundations of modern


interactive computers were laid decades earlier

Working Knowledge: In the Fast Lane

Electronic toll collection

Technicalities: Long-Distance Robots

The technology of telepresence makes the world even smaller

Puzzling Adventures: Fashion Gang

Fashionable mathematics

Nov 2001

ecology
On the Termination of Species

Ecologists' warnings of an ongoing mass extinction are being


challenged by skeptics and largely ignored by politicians. In
part that is because it is surprisingly hard to know the
dimensions of the die-off, why it matters and how it can best
be stopped

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info tech
The Electronic Paper Chase

Digital "paper" that displays changing text and graphics


would ideally marry the best features of traditional printed
materials with those of video screens. Companies are racing
to realize that promise using two competing technologies.
Already retailers are testing cost-saving changeable e-ink
signage. Pliable, updatable e-newspapers, e-books and even
an e-Scientific American could be here within a decade

biotech
Beyond Chicken Soup

The antiviral era is upon us, with an array of virus-fighting


drugs on the market and in development. Research into viral
genomes is fueling much of this progress

astronomy
Gravity's Kaleidoscope

The most massive telescopes known to humanity sit not on


earthly mountaintops but in deep space. They are
gravitational lenses, once mere curiosities, now one of the
most important tools in astronomy

evolution
The Evolution of Human Birth

The difficulties of childbirth have probably challenged


humans and their ancestors for millions of years - which
means that the modern custom of seeking assistance during
delivery may have similarly ancient roots

education
Does Class Size Matter?

Legislators are spending billions to reduce class sizes. Will the


results by worth the expense?

Working Knowledge: Current Safety

Ground fault circuit interrupters

Puzzling Adventures: Truck Stop

Mathematics of a truckers' stike

Oct 2001
biotech
Magic Bullets Fly Again

Molecular guided missiles called monoclonal antibodies were


poised to shoot down cancer and a host of other diseases until they crashed and burned. Now a new generation is
soaring to market

info tech
Code Red for the Web

Could the Internet crash? This summer's Code Red attacks


could foreshadow destructive cyberwarfare between hacker
groups or between governments

info tech
Driving the Info Highway

The Internet has hit the road. Drivers can now access
anything from custom traffic reports to spoken e-mail
messages to video games. But is it safe?

astrobiology, life science


Refuges for Life in a Hostile Universe

Only part of our galaxy is fit for advanced life

Researchers have begun to identify the causes of this dreaded


medicine
The Challenge of Macular Degeneration eye disease that targets the elderly

engineering
Drowning New Orleans

A major hurricane could swamp New Orleans under 20 feet


of water, killing thousands. Human activities along the
Mississippi River have dramatically increased the risk, and
now only massive reengineering of southeastern Louisiana
can save the city

Working Knowledge: Mice and Men

Computer mouse

Technicalities: A Wide Web of Worlds

New Internet browsers add an extra dimension - but little


depth

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Labyrinthine logic

Sep 2001
nanotech
Little Big Science

Nanotechnology is all the rage. But will it meet its ambitious


goals? And what the heck is it?

nanotech
Nanofabrication: The Art of Building
Small

Researchers are discovering cheap, efficient ways to make


structures only a few billionths of a meter across

nanotech
Nanophysics: Plenty of Room, Indeed

There is plenty of room for practical innovation at the


nanoscale. But first, scientists have to understand the unique
physics that governs matter there

nanotech
Nanoelectronics: The Incredible
Shrinking Circuit

Researchers have built nanotransistors and nanowires. Now


they just need to find a way to put them all together

nanotech
Nanomedicine: Less is More in
Medicine

Sophisticated forms of nanotechnology will find some of their


first real-world applications in biomedical research, disease
diagnosis and, possibly, therapy

nanotech
Nanovisions: Machine-Phase
Nanotechnology

A molecular nanotechnology pioneer predicts that the tiniest


robots will revolutionize manufacturing and transform society

nanotech
Nanofallacies: Of Chemistry, Love and
Nanobots

How soon will we see the nanometer-scale robots envisaged


by K. Eric Drexler and other molecular nanotechnologists?
The simple answer is never

nanotech
Nanoinspirations: The Once and Future
Nanomachine

Biology outmatches futurists' most elaborate fantasies for


molecular robots

nanotech
Nanorobotics: Nanobot Construction
Crews

Nanotechnology visionaries find out how difficult it is to


develop minuscule robots that can treat diseases or perform
pollution-free manufacturing

nanotech
Nanofiction: Shamans of Small

Like interstellar travel, time machines and cyberspace,


nanotechnology has become one of the core pilot devices on
which science-fiction writers draw

Working Knowledge: Flea Treatments

Killer drops

Puzzling Adventures: Square Dancing

Square dancing without collisions

Aug 2001
info tech
Go Forth and Replicate

Birds do it, bees do it, but could machines do it? New


computer simulations suggest that the answer is yes

astrochemistry
The Ice of Life

Ice in its earthly guise is hostile to living things. But an exotic


form of space ice can actually promote the creation of
organic molecules -and may have seeded life on Earth

biotech
Cybernetic Cells

The simplest living cell is so complex that supercomputer


models may never simulate its behavior perfectly. But even
imperfect models could shake the foundations of biology

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anthropology
Once Were Cannibals

Clear evidence of cannibalism in the human fossil record has


been rare, but it is now becoming apparent that the practice is
deeply rooted in our history

security
Taming the Killing Fields of Laos

Live bombs from the Vietnam War continue to kill people and
hamper agricultural development in Laos. The cleanup
project required deciphering decades-old computer files

info tech
The Do-It-Yourself Supercomputer

Scientists have found a cheaper way to solve tremendously


difficult computational problems: connect ordinary PCs so
that they can work together

ecology
The Trouble with Turtles

Despite heroic efforts to protect the nesting beaches of green


turtles, fewer and fewer of these endangered creatures
reappear every year. Researchers have been stunned to
discover that shielding young turtles is only half the battle

Working Knowledge: Crank It Up!

Human-powered electronics

Technicalities: Touchy-Feely Computing A new mouse picks up good vibrations


Puzzling Adventures: The Delphi Flip

Predicting the future accurately is most useful in betting


games - the stock market comes to mind

Jul 2001
info tech
How to Build a Hypercomputer

The simulation and ultimate solution of humanity's major ills


and most perplexing problems require significantly faster
supercomputers

psychology
The Truth and Hype of Hypnosis

Though often denigrated as fakery or wishful thinking,


hypnosis has been shown to be a real phenomenon with a
variety of therapeutic uses - especially in controlling pain

nanotech
Making Molecules into Motors

Molecular turmoil, quantum craziness: microscopic machines


must operate in a world gone mad. But if you can't beat the
chaos, why not exploit it?

physics
Frozen Light

Slowing a beam of light to a halt may pave the way for new
optical communications technology, tabletop black holes and
quantum computers

biotech
Battling Biofilms

The war is against bacterial colonies that cause some of the


most tenacious infections known. The weapon is knowledge
of the enemy's communication system

ecology
Fishy Business

Cyanide fishing threatens many of the last pristine coral reefs


in Southeast Asia. Will an ambitious program to clean up the
marine aquarium trade be enough to save them?

Working Knowledge: Tan or Burn

Protecting skin from the summer sun

Puzzling Adventures: Seeing Red,


Feeling Blue

Here's a puzzle full of clashing colors

Jun 2001
astrophysics
The Paradox of the Sun's Hot Corona

Like a boiling teakettle atop a cold stove, the sun's hot outer
layers sit on the relatively cool surface. And now astronomers
are figuring out why

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biology
Solving the Mystery of Insect Flight

Insects use a combination of aerodynamic effects to remain


aloft

neuroscience
Sign Language in the Brain

How does the human brain process language? New studies of


deaf signers hint at an answer

space science
North to Mars!

To pave the way for a mission to Mars, a band of scientists


decided to go to the Canadian arctic

biotech
Hair - Why It Grows Why It Stops

Scientists are rapidly discovering the molecules that control


hair production. In so doing, they could be unearthing the key
to combating both baldness and excessive hair growth

anthropology
The Himba and the Dam

A questionable act of progress may drown this African tribe's


way of life. Similar dramas are playing out around the world

technology
A Low-pollution Engine Solution

Clean-burning, sparkless-ignition auto engines may offer the


best chance of meeting new exhaust emissions standards

Working Knowledge: Flight Control

Golf balls

Technicalities: Kibbles and Bytes

How much is that robotic doggy in the window?

Puzzling Adventures: Alternating Liars

Liar, liar, liar

May 2001
info tech
The Semantic Web

A new form of Web content that is meaningful to computers


will unleash a revolution of new possibilities

astronomy
Rip Van Twinkle

The oldest stars have been growing younger

biotech
Behind Enemy Lines

A close look at the inner workings of microbes in the era of


escalating antibiotic resistance is offering new strategies for
designing drugs

environment
The Arctic Oil and Wildlife Refuge

The last great onshore oil field in America may lie beneath
the nation's last great coastal wilderness preserve. Science
can clarify the potential economic benefits and the ecological
risks of drilling into it

weaponry
Warp Drive Underwater

Traveling inside drag-cutting bubbles, secret torpedoes and


other subsea naval systems can move hundreds of miles per
hour

psychology
What's Wrong with This Picture?

Psychologists often use the famous Rorschach inkblot test


and related tools to assess personality and mental illness. But
research says the instruments are frequently ineffective for
those purposes

Working Knowledge: Quick Scan

Bar-code readers

Puzzling Adventures: Something Fishy

Retracing a villain's steps

Apr 2001
biotech
Whose Blood Is It, Anyway?

Blood collected from umbilical cords and placentas - which


are usually thrown away following birth - contains stem cells
that can rebuild the blood and immune systems of people
with leukemia and other cancers

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biotech
Genetically Modified Foods: Are They
Safe? - Introduction

A look at how much science really knows about the risks of


growing and eating genetically modified crops.

biotech
Genetically Modified Foods: Are They
Safe? - Seeds of Concern

Are genetically modified crops an environmental dream come


true or a disaster in the making? Scientists are looking for
answers

biotech
Genetically Modified Foods: Are They
Safe? - The Risks on the Table

More than half the foods in U.S. supermarkets contain


genetically modified ingredients. Have they been proved safe
for human consumption?

biotech
Genetically Modified Foods: Are They
Safe? - Does the World Need GM
Foods? (Q&A)

Two leading figures in the debate over genetic engineering


defend their stances

info tech
Virtually There

Three-dimensional tele-immersion may eventually bring the


world to your desk

chemistry
Life's Rocky Start

Air, water and rock were the only raw materials available on
the early earth. The first living entitities must been fabricated
from these primitive resources. New experiments suggest that
minerals - the basic components of the rocks - could have
played starring roles in that dramatic feat

astrophysics
The Fury of Space Storms

Shock waves from the sun can trigger severe turbulence in


the space around the earth, endangering satellites and
astronauts in orbit. Now a new spacecraft is showing how
space storms develop

psychology
Violent Pride

Do people turn violent because of self-hate, or self-love?

Working Knowledge: Touch Screens At Your Fingertips

A truly touchy interface

Technicalities: Look, Ma, No Wires!

The Ricochet wireless modem is like a Ferrari - fast but


pricey

Puzzling Adventures: No Tipping

A weighty search for leverage

Mar 2001
biology
Making Sense of Taste

How do cells on the tongue register the sensations of sweet,


salty, sour and bitter? Scientists are finding out - and
discovering how the brain interprets these signals as various
tastes

earth science
Sculpting the Earth from Inside Out

Powerful motions deep inside the planet do not merely shove


fragments of the rocky shell horizontally around the globe they also lift and lower entire continents

biology
If Humans Were Built to Last

We would look a lot different - inside and out - if evolution


had designed the human body to function smoothly not only
in youth but for a century or more

astronomy
A Sharper View of the Stars

A new generation of optical interferometers is letting


astronomers study stars in 100 times finer detail than is
possible with the Hubble Space Telescope

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evolution
Evolution: A Lizard's Tale

On some islands in the Caribbean, evolution seems to have


taken the same turn - over and over and over again

economics
The Geography of Poverty and Wealth

Tropical climate and lack of access to sea trade have hurt the
poorest nations. But new aid programs point the way to
prosperity

Working Knowledge: Gotcha!

How radar guns catch speeders

The Amateur Scientist: Geotropism, One


How plants grow in reduced gravity
Last Time
Mathematical Recreations: Easter Is a
Quasicrystal

The divine mathematics of a holiday

Feb 2001
environment
Special Report: Safeguarding Our
Water/Introduction

Drip, trickle, splash. Water is one of the most common


substances in the universe, and our ocean-wrapped planet is
blessed with a generous share of it. Unfortunately, 97 percent
of that share is salty, and much of the rest is locked up in ice.

environment
Special Report: Safeguarding Our
Water/Making Every Drop Count

We drink it, we generate electricity with it, we soak our crops


with it. And we're stretching our supplies to the breaking
point. Will we have enough clean water to satisfy all the
world's needs?

environment
Special Report: Safeguarding Our
Water/Growing More Food with Less
Water

If the world hopes to feed its burgeoning population,


irrigation must become less wasteful and more widespread

environment
Special Report: Safeguarding Our
Water/How We Can Do It

A look at four promising ways to maintain adequate supplies


of freshwater: desalination, new technologies for transporting
water, reducing demand, and recycling

biotech
Why the Y is So Weird

Our X and Y chromosomes make an odd couple. The X


resembles any other chromosome, but the Y - the source of
maleness - is downright strange. How did the two come to
differ so much?

technology
In Pursuit of the Ultimate Lamp

Full-spectrum light-emitting diodes, or LEDs, are becoming


widespread - and the race is on to develop white-light
versions to replace Edison's century-old incandescent bulb

physics
100 Years of Quantum Mysteries

As quantum theory celebrates its 100th birthday, spectacular


successes are mixed with persistent puzzles

psychology
The Science of Persuasion

Salespeople, politicians, friends and family all have a stake in


getting you to agree to their requests. Social psychology has
determined the basic principles that govern getting to "yes"

Working Knowledge: Preparing for


Battle

How vaccines prevent the flu

The Amateur Scientist: Counting


Particles from Space

How to build a cosmic-ray telescope

Mathematical Recreations: Pursuing


Polygonal Privacy

Good fences make good neighbors

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Jan 2001
cosmology
Brave New Cosmos: Introduction

Observational cosmology is about to become a mature


science. Explanations for the universe's unexpectedly odd
behaviors may then be around the corner

cosmology
Brave New Cosmos: Echoes from the
Big Bang

Scientists may soon glimpse the universe's beginnings by


studying the subtle ripples made by gravitational waves

cosmology
Brave New Cosmos: A Cosmic
Cartographer

The Microwave Anisotropy Probe will give cosmologists a


much sharper picture of the early universe

cosmology
Brave New Cosmos: The Quintessential
Universe

The universe has recently been commandeered by an


invisible energy field, which is causing its expansion to
accelerate outward

cosmology
Brave New Cosmos: Making Sense of
Modern Cosmology

Confused by all those theories? Good

cosmology
Brave New Cosmos: Plan B for the
Cosmos

If the new cosmology fails, what's the backup plan?

biology
The Cultures of Chimpanzees

Humankind's nearest relative is even closer than we thought:


chimpanzees display remarkable behaviors that can only be
described as social customs passed on from generation to
generation

biotech
The Cellular Chamber of Doom

Structures called proteasomes inside cells continously destroy


proteins. Several common diseases result when the process
works too zealously - or not at all

technology
The Mystery of Damascus Blades

Centuries ago craftsmen forged peerless steel blades. But how


did they do it? The author and a blacksmith have found the
answer

info tech
The Triumph of the Light

Extensions to fiber optics will supply network capacity that


borders on the infinite

info tech
The Rise of Optical Switching

Replacing electronic switches with purely optical ones will


become the technological linchpin for networks that transmit
trillions of bits each second

info tech
Routing Packets with Light

The ultimate all-optical network will require dramatic


advances in technologies that use one lightwave to imprint
information on another

Working Knowledge: The


Well-Rounded Flat Speaker

The rounded tones of flat-panel speakers

Mathematical Recreations:
Dots-and-Boxes for Experts

The secret subtleties of a children's game

The Amateur Scientist: A Canteen


Cloud Chamber

Viewing the path of charged particles

Dec 2000

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paleontology
Rulers of the Jurassic Seas

Fish-shaped reptiles called ichthyosaurs reigned over the


oceans for as long as dinosaurs roamed the land, but only
recently have paleontologists discovered why these creatures
were so successful

nanotech
Nanotubes for Electronics

They are stronger than steel, but the most important uses for
these threadlike macromolecules may be in faster, more
efficient and more durable electronic devices

astronomy
The Secrets of Stardust

Tiny grains of dust floating in interstellar space have radically


altered the history of our galaxy

medicine
Piecing Together Alzheimer?s

The stunningly complex biochemical puzzle that underlies


this crippling disease remains incomplete, but parts that
seemed unrelated just a decade ago are now fitting into place

urban planning
The Science of Smart Growth

Are there any alternatives to urban sprawl? Pundits and pols


may endlessly debate that question, but the only way to get
an answer is to go out and see what works in the real world

physics
The Coolest Gas in the Universe

Bose-Einstein condensates are one of the hottest areas in


experimental physics

Working Knowledge: Superabsorbers

Disposable diapers

The Amateur Scientist: Calibrating with


Cold

How to fine-tune a laboratory thermometer

Mathematical Recreations: Jumping


Champions

Counting the gaps between primes

Nov 2000
consumer electronics
Special Report: The Future of Digital
Entertainment/Introduction

The barriers separating TV, movies, music, video games and


the Internet are crumbling. Audiences are getting new
creative options. Here is what entertainment could become if
the technological and legal hurdles can be cleared.

consumer electronics
Special Report: The Future of Digital
Entertainment/Creating Convergence

TV, movies, Internet video, and music could morph into one
big stream of d-entertainment that we can enjoy on any
device, anywhere, anytime. But the devil is in the details

consumer electronics
Special Report: The Future of Digital
Entertainment/Music Wars

Internet distribution of quality d-audio is rapidly being


perfected, but the precedent-setting legal battles have just
begun

consumer electronics
Special Report: The Future of Digital
Entertainment/Moviemaking in
Transition

Digital video cameras and editing equipment are transforming


the way movies are made - even which movies get made

consumer electronics
Special Report: The Future of Digital
Entertainment/Digital Cinema Is for
Reel

Digital projection works,but it's not at a theater near you - yet

consumer electronics
Special Report: The Future of Digital
Entertainment/Digital Humans Wait in
the Wings

Characters, scenes and entire movies have been crafted


digitally. But can animators create realistic humans to star in
computer-generated films? Actors want to know

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consumer electronics
Special Report: The Future of Digital
Entertainment/Your Own Virtual
Storyworld

True interactive entertainment will arise once engineers and


artists create virtual realities that can unfold improvisationally

biotech
Cloning Noah's Ark

Biotechnology might offer the best way to keep some


endangered species from disappearing from the planet

space science
The Vasimir Rocket

There used to be two types of rocket: powerful but


fuel-guzzling, or efficient but weak. Now there is a third
option that combines the advantages of both

medicine
AIDS Drugs for Africa

Most of the 35 million people infected with the AIDS virus


live on the African continent, where drugs that fight the virus
are rare. Will the world let them die?

history
The Odd Couple and the Bomb

Like a story by Victor Hugo as told to Neil Simon, the events


leading up to the first controlled nuclear chain reaction
involved accidental encounters among larger-than-life figures,
especially two who did not exactly get along ? but had to

Working Knowledge: Pregnancy Tests

How home pregnancy tests work.

The Amateur Scientist: Boids of a


Feather Flock Together

Simulating boids, floys and other artificial life.

Mathematical Recreations: Spiral Slime

How nature draws spirals and shapes.

Oct 2000
info tech
The Wireless Web: Special
Report/Introduction

The Internet has been the subject of more self-parodying


hype than anything since 500-channel cable.

info tech
The Wireless Web: Special Report/The
Internet in Your Hands

To spur the growth of the wireless Web, companies are


developing networks that can handle huge amounts of data
and handheld devices that can tap into all the Internet's
resources

info tech
The Wireless Web: Special Report/The
Promise and Perils of WAP

The Wireless Application Protocol allows cell phone users to


connect to the Internet, but the technology has serious
limitations

info tech
The Wireless Web: Special Report/The
Future is Here. Or Is It?

How will Web phones ever become popular if it takes 10


minutes and costs $4 to send one e-mail?

info tech
The Wireless Web: Special Report/The
Third-Generation Gap

A revolution needs a plan. Which technology will provide it?

medicine
Operating on a Beating Heart

Coronary bypass surgery can be a lifesaving operation. Two


new surgical techniques should make the procedure safer and
less expensive

life science
The Power of Memes

Behaviors and ideas copied from person to person by


imitation - memes - may have forced human genes to make us
what we are today

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archaeology
Nabada: The Buried City

Excavations in northern Syria reveal the metropolis of


Nabada, founded 4,500 years ago. Its elaborate
administration and culture rivaled those of the fabled cities of
southern Mesopotamia

mathematics
Better Decisions through Science

Math-based aids for making decisions in medicine and


industry could improve many diagnoses - often saving lives in
the process

Working Knowledge: The Hard and the


Soft

Contact lenses: something in your eye?

The Amateur Scientist: Down among the


High-precision scales bring balance to home labs.
Micrograms
Mathematical Recreations: MillionDollar Minesweeper

How a computer game can make you rich

Sep 2000
biology
Muscle, Genes and Athletic
Performance

The cellular biology of muscle helps to explain why a


particular athlete wins and suggests what future athletes
might do to better their odds

astronomy
Searching for Shadows of Other Earths

Astronomers have found dozens of giant planets beyond our


solar system, but they haven't been capable of bagging an
Earth - until now

biotech
Edible Vaccines

One day children may get immunized by munching on foods


instead of enduring shots. More important, food vaccines
might save millions who now die for lack of access to
traditional inoculants

The briefest man-made events, pulses of laser light lasting


physics
millionths of a nanosecond, can be used for delicate eye
Ultrashort-Pulse Lasers: Big Payoffs in a
surgery, high-bandwidth communications and stop-motion
Flash
studies of molecules reacting
anthropology
Who Were the First Americans?

If your answer was fur-clad mammoth hunters, guess again.


The first people to settle the New World may have been
fisherfolk and basket weavers

engineering
The Plan to Save Fallingwater

This breathtaking house designed by Frank Lloyd Wright was


in danger of collapse until an engineering firm found a way to
stop it from falling down

Working Knowledge: A Better Black


Box

How do black boxes survive plane crashes?

The Amateur Scientist: Using a Kite as


an Experimental Platform

Kites carry eyes in the sky

Mathematical Recreations: Hex Marks


the Spot

The mind-bending challenge of Hex.

Aug 2000
materials science
How Green Are Green Plastics?

It is now technologically possible to make plastics using green


plants rather than nonrenewable fossil fuels. But are these
new plastics the environmental saviors researchers have

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hoped for?
astronomy
Fountains of Youth: Early Days in the
Life of a Star

To make a star, gas and dust must fall inward. So why do


astronomers see stuff streaming outward?

climate change
Is Global Warming Harmful to Health?

Computer models indicate that many diseases will surge as


the earth's atmosphere heats up. Signs of the predicted
troubles have begun to appear

chemistry
Form from Fire

Self-propagating heat waves can engender new and improved


materials, but only recently have researchers found ways to
monitor these ultraquick chemical reactions

physics
The Universe's Unseen Dimensions

The visible universe could lie on a membrane floating within


a higher-dimensional space. The extra dimensions would help
unify the forces of nature and could contain parallel universes

biology
Male Sexual Circuitry

The brain is the most important sex organ. One of its roles in
male sexuality is to keep the penis under control.

nutrition
Birth of the Modern Diet

Ever wonder why dessert is served after dinner? The origins


of modern Western cooking can be traced to ideas about diet
and nutrition that arose during the 17th century

Working Knowledge: Focusing in a


Flash

Cheese! How cameras autofocus

The Amateur Scientist: How to Rear a


Plankton Menagerie

Raising a plankton menagerie.

Mathematical Recreations: A Fractal


Guide to Tic-Tac-Toe

A familiar shape in unexpected places

Jul 2000
life science
Special Industry Report: The Business
of the Human Genome (Introduction)

The task of sequencing all human DNA is all but done, but
mining the mountains of genetic information for pay dirt is
just beginning

life science
Special Industry Report: The Human
Genome Business Today

It's been a wild ride for the corporate and government parties
who have deciphered the human genetic code. The fun has
just begun

life science
Special Industry Report: The
Bioinformatics Gold Rush

A $300-million industry has emerged around turning raw


genome data into knowledge for making new drugs

life science
Special Industry Report: Beyond the
Human Genome

With all of the DNA that codes for a human in hand, the
challenge then becomes what to make of it. Some of the first
fruits will come from a new field called proteomics

physics
The Large Hadron Collider

The Large Hadron Collider will be a particle accelerator of


unprecedented energy and complexity, a global collaboration
to uncover an exotic new layer of reality

evolution
Darwin's Influence on Modern Thought

Great minds shape the thinking of successive historical


periods. Luther and Calvin inspired the Reformation; Locke,
Leibnitz, Voltaire and Rousseau, the Enlightenment. Modern
thought is most dependent on the influence of Charles

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Darwin
engineering
The Revolutionary Bridges of Robert
Maillart

Swiss engineer Robert Maillart built some of the greatest


bridges of the 20th century. His designs elegantly solved a
basic engineering problem: how to support enormous weights
using a slender arch

earth science
The Killing Lakes

Two lakes in Cameroon are poised to release lethal gas, as


they did in the 1980s. Writer Marguerite Holloway reports on
scientists' efforts to prevent another tragedy

Working Knowledge: Escape and


Survival

With luck, the unnecessary space suit.

The Amateur Scientist: PCR at Home

Copying DNA in your kitchen.

Mathematical Recreations: Knotting


Ventured...

How pieces of string can illustrate the principles of symmetry

Jun 2000
weaponry
Special Report: Waging a New Kind of
War (Introduction)

What could possibly be new about war? People have always


been quite imaginative about finding ways to impose their
will by violent force. Rocks and spears, catapults and
muskets, mustard gas and nukes: you might think that human
civilization has tried it all. Evidently not.

weaponry
Special Report: A Scourge of Small
Arms

With a few hundred machine guns and mortars, a small army


can take over an entire country, killing and wounding
hundreds of thousands

weaponry
Special Report: Invisible Wounds

Medical researchers have recently begun to address the


mental health effects of war on civilians

weaponry
Special Report: Children of the Gun

How do you make a child into a killer? Armed groups


worldwide have developed a grim routine: abduct children
from their families, inure them to abuse and "promote" them
into combat

astronomy
Dwarf Galaxies and Starbursts

Diminutive galaxies occasionally experience spectacular


bursts of star formation. These starbursts are giving
astronomers a glimpse of the universe's early history

biology
Cell Communication: The Inside Story

The tiny cells in our bodies harbor amazing internal


communication networks. Understanding how those circuits
are organized could help scientists develop new therapies for
many serious disorders

anthropology
Reading the Bones of La Florida

New approaches are offering insight into the lives of Native


Americans after the Europeans arrived. Their health declined
not only because of disease but because of their altered diet
and living circumstances

biotech
Computing with Molecules

Researchers have produced molecules that act like switches,


wires and even memory elements. But connecting many of
the devices together presents enormous challenges

biology
Looking for Life Below the Bottom

Two scientists have a hunch that the largest repository of life


is not the oceans but the fractured rock beneath them. Staff
writer Sarah Simpson recounts the voyage to find proof

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May 2000
astronomy
The Small Planets

Asteroids have become notorious as celestial menaces but are


best appreciated in a positive light, as surreal worlds bearing
testimony to the origin of the planets

info tech
Special Industry Report: Avoiding A
Data Crunch

The technology of computer hard drives is fast approaching a


physical barrier imposed by the superparamagnetic effect.
Overcoming it will require tricky innovations

biology
Coping with Crowding

A persistent and popular view holds that high population


density inevitably leads to violence. This myth, which is
based on rat research, applies neither to us nor to other
primates

physics
Making Metallic Hydrogen

By re-creating extreme conditions like those in Jupiter's core,


physicists have at long last turned hydrogen into a metal

medicine
Care for a Dying Continent

In Zimbabwe - where AIDS is prematurely killing a


generation of adults - counselors and researchers struggle
against social customs, viral resourcefulness and despair

Apr 2000
physics
Quantum Teleportation

The science-fiction dream of "beaming" objects from place to


place is now a reality - at least for particles of light

biotech
Building a Brainier Mouse

By genetically engineering a smarter than average mouse,


scientists have assembled some of the central molecular
components of learning and memory

medicine
Understanding Clinical Trials

The journey from initial medical research to the bottle in your


family's medicine cabinet is complex, time-consuming and
expensive. Can the clinical trial process be refined?

astronomy
The Discovery of Brown Dwarfs

Less massive than stars but more massive than planets, brown
dwarfs were long assumed to be rare. New sky surveys,
however, show that the objects may be as common as stars

anthropology
The Aleutian Kayak

The Aleuts built the baidarka to suit their life as hunters on


the open ocean. The sophisticated design of this kayak is still
not entirely understood

environment
Monitoring Earth's Vital Signs

A new NASA satellite - one of a fleet called the Earth


Observing System - is using five state-of-the-art sensors to
diagnose the planet's health like never before

anthropology
Who Were the Neandertals?

Controversial evidence indicates that these hominids


interbred with anatomically modern humans and sometimes
behaved in surprisingly modern ways

Mar 2000
space science
Why Go to Mars?

In the first of this group of articles about human missions to


Mars, staff writer Glenn Zorpette examines the main goal:
looking for life

space science
How to Go to Mars?

Staff writers George Musser and Mark Alpert make sense of


the myriad ideas for a human mission

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space science
The Mars Direct Plan

A leading advocate of manned missions to Mars, Robert


Zubrin, outlines his relatively inexpensive plan to send
astronauts to the Red Planet within a decade

space science
To Mars By Way of its Moons

Phobos and Deimos would make ideal staging areas, argues


veteran space scientist S. Fred Singer

space science
A Bus Between the Planets

Gravity-assist trajectories between Earth and Mars would


reduce the cost of shuttling human crews and their
equipment, say James Oberg and Buzz Aldrin

space science
Staying Sane in Space

Is the "right stuff" enough? asks staff writer Sarah Simpson

space science
Invaders from Hollywood

Thanks to Pathfinder and other missions, science gets some


respect in Tinseltown, as staff writer Philip Yam finds after
touchdown on a Vancouver set

biotech
The Tick-Tock of the Biological clock

Biological clocks count off 24-hour intervals in most forms of


life. Genetics has revealed that related molecular timepieces
are at work in fruit flies, mice and humans

mathematics
Swarm Smarts

Using ants and other social insects as models, computer


scientists have created software agents that cooperate to
solve complex problems, such as the rerouting of traffic in a
busy telecom network

environment
Dissecting a Hurricane

Flying into the raging tumult of Dennis, scientists suspected


that the storm might transform into a monster - if they were
lucky

biology
The Bromeliads of the Atlantic Forest

Along the coast of Brazil, 8 percent of a once flourishing


forest is left to house a diverse family of bromeliads. A group
of biologists scale cliffs and trees to collect these rare
beauties

Feb 2000
astronomy
The Galileo Mission to Jupiter and Its
Moons

Few scientists thought that the Galileo spacecraft, beset by


technical troubles, could conduct such a comprehensive study
of the Jovian system. And few predicted that the innards of
these worlds would prove so varied

materials science
Melting Below Zero

New research shows how a layer of water on the surface of


ice - even at temperatures well below freezing - can influence
everything from the slipperiness of a skating rink to the
electrification of thunderclouds

neuroscience
The Early Origins of Autism

New research into the causes of this baffling disorder is


focusing on genes that control the development of the brain

The next step in creating more realistic computer-generated


images is the development of better models of the physical
info tech
Digital Materials and Virtual Weathering structures of materials and their degradation by the
environment
climate change
Capturing Greenhouse Gases

Sequestering carbon dioxide underground or in the deep


ocean could help alleviate concerns about climate change

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biology
Transparent Animals

Ingenious physiological accommodations have evolved to


enable a stunning variety of undersea creatures to be
remarkably transparent

biology
Uprooting the Tree of Life

About 10 years ago scientists finally worked out the basic


outline of how modern life-forms evolved. Now parts of their
tidy scheme are unraveling

Jan 2000
physics
Negative Energy, Wormholes and Warp
Drive

The construction of wormholes and warp drive would require


a very unusual form of energy. Unfortunately, the same laws
of physics that allow the existence of this "negative energy"
also appear to limit its behavior

anthropology
Once We Were Not Alone

Today we take for granted that Homo Sapiens is the only


hominid on Earth. Yet for at least four million years many
hominid species shared the planet. What makes us different?

chemistry
Voyage to SUPERHEAVY Island

The synthesis of element 114 confirmed decades-old


theoretical predictions of a little patch of nuclear stability in a
sea of short-lived superheavy nuclei

earth science
Snowball Earth

Ice entombed our planet hundreds of millions of years ago,


and complex animals evolved in the greenhouse heat wave
that followed

medicine
Narcolepsy

Although people with the disorder do not fall face-first into


their soup as in the movies, narcolepsy is still a mysterious
disease. But science has new leads

technology
Maglev: A New Approach

The Inductrack promises a safer, cheaper system for


magnetically levitating trains. The same technology can also
be used to launch rockets

public health
The Unmet Need for Family Planning

Women and men in many countries still lack adequate access


to contraceptives. Unless they are given the option of
controlling their fertility, severe environmental and health
problems loom in the coming century throughout large parts
of the world

The Amateur Scientist

Detecting Extraterrestrial Gravity

Mathematical Recreations

Impossibility Theorems

Dec 1999
The Unexpected Science to Come

The most important discoveries of the next 50 years are likely


to be ones of which we cannot now even conceive

A Unified Physics by 2050?

Experiments at CERN and elsewhere should let us complete


the Standard Model of particle physics, but a unified theory
of all forces will probably require radically new ideas

Exploring Our Universe and Others

In the 21st century cosmologists will unravel the mystery of


our universe's birth - and perhaps prove the existence of other
universes as well

Deciphering the Code of Life

The study of all the genes of various organisms will yield


answers to some of the most intriguing questions about life

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The End of Nature versus Nurture

Is human behavior determined by genetics or by


environment? It may be time to abandon the dichotomy

The Human Impact on Climate

How much of a disruption do we cause? The much-awaited


answer could be ours by 2050, but only if nations of the
world commit to long-term monitoring now

Can Human Aging Be Postponed?

In theory, it certainly can. Yet no single elixir will do the


trick. Antiaging therapies of the future will undoubtedly have
to counter many destructive biochemical processes at once

How the Brain Creates the Mind

Philosophers, neuroscientists and laypeople have long


wondered how the conscious mind comes to be. A more
complete understanding of the workings of the brain ought to
lead to an eventual solution

Is There Life Elsewhere in the


Universe?

The answer is: nobody knows. Scientists' search for life


beyond Earth has been less thorough than commonly thought.
But that is about to change

Rise of the Robots

By 2050 robot "brains" based on computers that execute 100


trillion instructions per second will start rivaling human
intelligence

Mathematical Recreations

Defend the Roman Empire!

Nov 1999
The Fate of Life in the Universe

Billions of years ago the universe was too hot for life to exist.
Countless eons hence, it will become so cold and empty that
life, no matter how ingenious, will perish

Vision: A Window on Consciousness

In their search for the mind, scientists are focusing on visual


perception - how we interpret what we see

Flammable Ice

Methane-laced ice crystals in the seafloor store more energy


than all the world's fossil fuel reserves combined. But these
methane hydrate deposits are fragile, and the gas that escapes
from them may exacerbate global warming

Slave-Making Queens

Life in certain corners of the ant world is fraught with


invasion, murder and hostage-taking. The battle royal is a
form of social parasitism

Time-Reversed Acoustics

Arrays of transducers can re-create a sound and send it back


to its source as if time had been reversed. The process can be
used to destroy kidney stones, detect defects in materials and
communicate with submarines

Floating in Space

Balloons offer scientists a low-cost, quick-response way to


study the upper reaches of Earth's atmosphere and those of
other planets

A Zeppelin for the 21st Century

By developing new aerodynamic computer models and using


modern materials, the company that originated zeppelins has
returned them to the skies over Europe

The Balloon That Flew round the World

To build a balloon capable of circumnavigating the globe,


engineers ripped a page from aeronautical history

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The Grameen Bank

A small experiment begun in Bangladesh has turned into a


major new concept in eradicating poverty

The Amateur Scientist

Falling into Chaos

Mathematical Recreations

Most-Perfect Magic Squares

Oct 1999
The Hidden Ocean of Europa

Doodles and freckles, creamy plains and crypto-icebergs - the


amazing surface of Jupiter's brightest icy moon hints at a
global sea underneath

Why Things Break

Scientists have known for most of this century that chemistry


is responsible for whether a solid shatters or bends. But only
now are they finding a way to predict which type of failure
will win

Preserving Nefertari's Legacy

The tomb of this ancient Egyptian queen is testament to the


great love of Pharaoh Ramses II. Its preservation is testament
to advances in conservation

The Unmet Challenges of Hepatitis C

Some 1.8 percent of the U.S. adult population are infected


with the hepatitis C virus, most without knowing it

The False Crisis in Science Education

The largely mythical decline of science in the public schools


is leading - yet again - to rushed reforms that ignore the best
advice on what kids should know

High-Speed Data Races Home

The global network is entering a new phase in its evolution,


one that will spawn new applications and make dial-up
modems a thing of the past

The Internet via Cable

Only cable networks are well equipped to provide hybrid


TV-Internet services, as well as superfast on-line access

DSL: Broadband by Phone

Alexander Graham Bell's ubiquitous copper wires will still be


a capacity-rich communications resource in the third
millennium

The Broadest Broadband

New technologies promise to reduce the cost of linking


homes with optical fiber, the ultimate medium for data
communications

Satellites: The Strategic High Ground

Data communications systems that use satellites to transmit


signals have many advantages over ground-based systems

LMDS: Broadband Wireless Access

Ground-based wireless networks delivering the full range of


broadband services can be deployed quickly and
inexpensively

The Light at the End of the Pipe

A much faster and easier-to-use Internet will stimulate the


introduction of new services and possibly even significant
social metamorphoses

Mathematical Recreations

Cone with a Twist

The Amateur Scientist

Modeling the Atomic Universe

Sep 1999

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By analyzing previously overlooked fossils and by taking a


Breathing Life into "Tyrannosaurus rex" second look at some old finds,paleontologists are providing
the first glimpses of the actual behavior of the tyrannosaurs
The Teeth of the Tyrannosaurs

Their teeth reveal aspects of their hunting and feeding habits

The Dechronization of Sam Magruder

"The brute - it was a tyrannosaur - got me by the leg. He


shook me loose, tearing off the leg at the knee, and he didn't
see where the rest of me fell. I tied up the stump and crawled
away...."

Migrating Planets

Did the solar system always look the way it does now? New
evidence indicates that the outer planets may have migrated
to their present orbits

Repairing the Damaged Spinal Cord

Once little more than a futile hope, some restoration of the


injured spinal cord is beginning to seem feasible

A Case against Virtual Nuclear Testing

The U.S. Department of Energy's high-tech plan to replace


nuclear testing with elaborate 3-D computer simulations is
seriously flawed

The Throat Singers of Tuva

Testing the limits of vocal ingenuity, throat-singers can create


sounds unlike anything in ordinary speech and song - carrying
two musical lines simultaneously, say, or harmonizing with a
waterfall

Scientists and Religion in America

Science and religion are engaging in more active dialogue and


debate, but a survey suggests that scientists' beliefs have
changed little since the 1930s, and top scientists are more
atheistic than ever before

The Amateur Scientist

Counting Atmospheric Ions

Mathematical Recreations

Dances with Dodecahedra

Aug 1999
Why National Missile Defense Won't
Work

The current plan for defending the U.S. against a ballisticmissile attack faces many of the problems that plagued a
similar plan three decades ago

The Lurking Perils of "Pfiesteria"

This minute creature has been implicated in dramatic fish kills


and has hurt people. But its most publicized actions may not
be the most damaging. More subtle effects are raising new
concerns

The Future of Computing

M.I.T.'s Laboratory for Computer Science is developing a


new infrastructure for information technologies - the Oxygen
system - that promises to realize a vision long held by the
lab's director: helping people do more by doing less

Talking with Your Computer

Speech-based interfaces may soon allow computer users to


retrieve data and issue instructions without lifting a finger

Communications Chameleons

Multipurpose communications systems will be the links of


tomorrow's wireless computer networks

Raw Computation

One of the main engines of the Oxygen project is the Raw


microchip, which has wiring that can be automatically

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reprogrammed for different tasks


Detecting Massive Neutrinos

A giant detector in the heart of Mount Ikenoyama in Japan


has demonstrated that the neutrino metamorphoses in flight,
strongly suggesting that these ghostly particles have mass

The Moral Development of Children

It is not enough for kids to tell right from wrong. They must
develop a commitment to acting on their ideals. Enlightened
parenting can help

Trailing a Virus

As a virus never seen before swept through rural Malaysia,


killing more than 110 and forcing the destruction of a million
swine, it revealed the world's vulnerability to new diseases.
Even the best efforts of top scientists are sometimes not
enough to thwart them

The Amateur Scientist

Sun of a Gun

Mathematical Recreations

Sierpinski's Ubiquitous Gasket

Jul 1999
Looking back at Apollo

On the 30th anniversary of the first manned lunar landing,


digital reproductions of the Apollo photographs show the
moon as the astonauts saw it

Life's Far-Flung Raw Materials

Life may owe its start to complex organic molecules


manufactured in the icy heart of an interstellar cloud

Genetic Vaccines

Vaccines crafted from genetic material might one day prevent


AIDS, malaria and other devastating infections that defy
current immunization technologies. They may even help treat
cancer

The Mystery of Nucleon Spin

A new generation of experiments promises to pin down more


of the still uncertain internal structure of protons and
neutrons

The Earliest Zoos and Gardens

More than 4,000 years ago rulers in Egypt and Mesopotamia,


builders of pyramids and empires, became the first to embark
on another pastime: collecting exotic animals and planting
ornamental gardens

The Future Of Fuel Cells

The obstacles to building practical fuel cells are numerous,


but continued innovation and skillful engineering could make
them competitive

The Electrochemical Engine for


Vehicles

Fuel cells can power cleaner buses and cars, but key
engineering and economic obstacles will delay widespread
adoption of the technology

The Power Plant in Your Basement

In the past, stationary fuel cells were megawatt behemoths,


designed for the electric utilities. Now they are being shrunk
for homes and other modest applications

Replacing the Battery in Portable


Electronics

Batteries are cumbersome and expensive. Miniature fuel cells


could supplant them in cellular phones, laptop computers,
camcorders and other consumer products

The Amateur Scientist

Detecting the Earth's Electricity

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The Art of Elegant Tiling

Jun 1999
Mapping the Universe

Using techniques drawn from the analysis of music,


astronomers have been studying how galaxies form into
progressively larger groupings

How The Body tells Left from Right

The precise orientation of our internal organs - and those of


all other animals with a backbone - is controlled in part by
proteins that are produced on only one side of an embryo

Hypersearching the Web

With the volume of on-line information in cyberspace


growing at a breakneck pace, more effective search tools are
desperately needed. A new technique analyzes how Web
pages are linked together

Image-Guided Surgery

Virtual-reality technology is giving surgeons the equivalent of


x-ray vision, helping them to remove tumors more effectively,
to minimize surgical wounds and to avoid damaging critical
tissues

Biological Warfare against Crops

Intentionally unleashing organisms that kill an enemy's food


crops is a potentially devastating weapon of warfare and
terrorism

Gdel and the Limits of Logic

Mathematical genius Kurt Gdel was devoted to rationality in


his work but struggled with it in his personal life

Chasing the Ghost Bat

On jungle rivers in Belize, two zoologists catch the ultrasonic


cries of bats - and fish for a big one

The Amateur Scientist

Expert Secrets for Preserving Plants

Mathematical Recreations

Crossed Lines in the Brick Factory

May 1999
Unmasking Black Holes

Until recently, the evidence for black holes was


circumstantial. Now astronomers may have direct proof:
energy is vanishing from volumes of space without a trace

New Nerve Cells for the Adult Brain

Contrary to dogma, the human brain does produce new nerve


cells in adulthood. Can our newfound capacity lead to better
treatments for neurological diseases?

Tsunami!

Its awesome fury cannot be diminished, but lessons learned


from a rash of disasters this decade - and a new way to track
these killer waves - will help save lives

Killer Kangaroos and Other Murderous


Marsupials

Australian mammals were not all as cute as koalas. Some


were as ferocious as they were bizarre

Ada and the First Computer

The collaboration between Ada, countess of Lovelace, and


computer pioneer Charles Babbage resulted in a landmark
publication that described how to program the world's first
computer

The Andaman Islanders

The aboriginal inhabitants of a stretch of islands near India


offer a fascinating glimpse into the way of life of traditional

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hunter-gatherers. But how long will this window to our past


remain open?
XML and the Second-Generation Web

The combination of hypertext and a global Internet started a


revolution. A new ingredient, XML, is poised to finish the job

The Amateur Scientist

Hot Views of the Microscopic World

Mathematical Recreations

A Puzzle for Pirates

Apr 1999
Growing New Organs

Researchers have taken the first steps toward creating


semisynthetic, living organs that can be used as human
replacement parts

Embryonic Stem Cells for Medicine

Cells able to generate virtually all other cell types have


recently been isolated. One day they could help repair a wide
variety of damaged tissues

Encapsulated Cells as Therapy

An emerging approach to treating disease combines living


cells with plastic membranes that shield the cells from
immune attack

Skin: The First Tissue-Engineered


Products

Last year the first living, tissue-engineered skin product


became commercially available - and a second is expected to
be on the market within a few months. Top researchers from
each of the two companies involved tell how their products
came to be

Tissue Engineering: The Challenges


Ahead

The obstacles to building new organs from cells and synthetic


polymers are daunting but surmountable

Is Space Finite?

Conventional wisdom says the universe is infinite. But it


could be finite, merely givingthe illusion of infinity. Upcoming
measurements may finally answer this ancient question.

Alan Turing's Forgotten Ideas in


Computer Science

Well known for the machine, test and thesis that bear his
name, the British genius also anticipated neural-network
computers and "hypercomputation"

A New Eye Opens on the Cosmos

On the highest mountain in the pacific basin, a 10-year


odyssey will culminate in the capture of first light for a
telescope that may surpass space-based observatories

The Revival of Colored Cotton

A new arrival on the Western fashion market, naturally


pigmented cotton originally flourished some 5,000 years ago.
Its revival today draws on stocks first developed and
cultivated by Indians in South and Central America.

The Amateur Scientist

Detecting "Hot" Clouds

Mathematical Recreations

Tangling with Topology

Mar 1999
Global Climate Change on Venus

Venus's climate, like Earth's, has varied over time - the result
of newly appreciated connections between geologic activity
and atmospheric change

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A Little Big Bang

A new collider will soon create matter as dense and hot as in


the early universe

The Timing of Birth

A hormone unexpectedly found in the human placenta turns


out to influence the timing of delivery. This and related
findings could yield much needed ways to prevent premature
labor

Visualizing Human Embryos

A technique called magnetic resonance microscopy is


revealing the secrets of early human development

The Komodo Dragon

On a few small islands in the Indonesian archipelago, the


world's largest lizard reigns supreme

The Crash in the Machine

Increasingly, automakers are relying on computer simulations


of accidents to develop safer cars more quickly and
efficiently

The inventor of the Soviet hydrogen bomb became an


The Metamorphosis of Andrei Sakharov advocate of peace and human rights. What led him to his
fateful decision?
The Amateur Scientist

A Homemade High-Precision Thermometer

Mathematical Recreations

The Synchronicity of Firefly Flashing

Feb 1999

Supersoft X-ray Stars and Supernovae

Several years ago astronomers came across a new type of star


that spews out unusually low energy x-rays. These so-called
supersoft sources are now thought to be white dwarf stars
that cannibalize their stellar companions and then, in many
cases, explode

The Puzzle of Hypertension in AfricanAmericans

Genes are often invoked to account for why high blood


pressure is so common among African-Americans. Yet the
rates are low in Africans. This discrepancy demonstrates how
genes and the environment interact

Cichlids of the Rift Lakes

The extraordinary diversity of cichlid fishes challenges


entrenched ideas of how quickly new species can arise

A Multifractal Walk down Wall Street

The geometry that describes the shape of coastlines and the


patterns of galaxies also elucidates how stock prices soar and
plummet

How Limbs Develop

A protein playfully named Sonic hedgehog is one of the


long-sought factors that dictate the pattern of limb
development

The Way to Go in Space

To go farther into space, humans will first have to figure out


how to get there cheaply and more efficiently. Ideas are not
in short supply

Air-Breathing Engines

For years, engineers have dreamed of building an aircraft that


could reach hypersonic speeds, greater than Mach 5, or five
times the speed of sound.

Space Tethers

When humans begin to inhabit the moon and planets other


than Earth, they may not use the modern technology of

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rockets.
Highways of Light

Today's spacecraft carry their source of power.

Light Sails

Science-fiction dreams of worlds beyond our own solar


system have taken on a more realistic aspect since
astronomers discovered that the universe contains planets in
unexpectedly large numbers

Compact Nuclear Rockets

Someday, in exploring the outer planets of our solar system,


humankind will want to do more than send diminutive probes
that merely fly rapidly by them.

Reaching for the Stars

The notion of traveling to the stars is a concept compelling


enough to recur in countless cultural artifacts, from Roman
poetry to 20th-century popular music

The Amateur Scientist

Tackling the Triple Point

Mathematical Recreations

Origami Tessellations

Jan 1999

Surveying Space-time with Supernovae

Exploding stars seen across immense distances show that the


cosmic expansion may be accelerating - a sign that the
universe may be driven apart by an exotic new form of
energy

Cosmological Antigravity

The long-derided cosmological constant-a contrivance of


Albert Einstein's that represents a bizarre form of energy
inherent in space itself-is one of two contenders for
explaining changes in the expansion rate of the universe

Inflation in a Low-Density Universe

Evidence has gradually accumulated that the universe has


less matter, and therefore is expanding faster, than the theory
of inflation traditionally predicts. But a more sophisticated
version of the theory readily explains the observations

Child Care among the Insects

Why do some insect parents risk their lives to care for their
young?

Disarming Flu Viruses

Coming soon: new medicines designed to treat the flu by


halting viral replication in human tissues. The drugs may also
serve as a novel kind of preventive

Y2K: So Many Bugs...So Little Time

Fixing Y2K seems simple: change all two-digit years to four


digits. But that tedious - and unexpectedly difficult - process
takes more time than is left

DNA Microsatellites: Agents of


Evolution?

Repetitive DNA sequences play a surprising role in how


bacteria - and perhaps higher organisms - adapt to their
environments. On the downside, they have also been linked
to human disease

Expeditions: To Save a Salmon

On Vancouver Island, fisheries scientists are trying to find out


whether commercial fishing and cohos can coexist

The Amateur Scientist

Taking the Earth's Magnetic Pulse

Mathematical Recreations

Division without Envy

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Dec 1998
The Evolution of Galaxy Clusters

The most massive objects in the universe are huge clusters of


galaxies and gas that have slowly congregated over billions of
years. The process of agglomeration may now be ending

Cloning for Medicine

Now that genetically modified and copied mammals are a


reality, biomedical researchers are starting to develop
imaginative ways to use this technology

Making Ultrabright X-rays

Radiation a billion times brighter than the sun's is illuminating


a host of scientific and technical phenomena

Combating Prostate Cancer

Recent advances in diagnosis and treatment promise to


extend survival time and improve the quality of life for many
patients

Leafy Sea Dragons

These masters of camouflage are fierce predators - and one of


the few species in which males become pregnant

Building the Better Bug

Inserting new genes into a few specific insect species could


stop some infectious diseases, benefit agriculture and produce
innovative materials

Physicists in Wartime Japan

During the most trying years of Japan's history, two brilliant


schools of theoretical physics flourished

Sizing Up Software

Unlike oil, steel or paper, software is an intangible


commodity. This elusive quality makes computer programs
difficult to quantify

The Amateur Scientist

Sorting Molecules With Electricity

Mathematical Recreations

Your Half's Bigger Than My Half!

Nov 1998
Natural Oil Spills

In the Gulf of Mexico, a region famous for its many oil and
gas fields, most of the petroleum flowing into the ocean leaks
naturally from fissures in the seabed

The Meteorite Hunter, Part I: The Day


the Sands Caught Fire

A desert impact site demonstrates the wrath of rocks from


space

Meteorite Hunters Part II: The Search


for Greenland's Mysterious Meteor

Caught on camera, the fireball that streaked across Arctic


skies last December appeared to move too fast for anything
from this solar system. A monthlong expedition on this island
of ice hunted for remains - and answers

Glueballs

Gluons, which hold protons together, can also clump into


globs of pure glue

Evolution and the Origins of Disease

The principles of evolution by natural selection are finally


beginning to inform medicine

Mating Strategies of Spiders

Spiders have evolved intriguing behaviors to woo their


occasionally cannibalistic mates

Simulating Water and the Molecules of


Life

Computer modeling reveals how water affects the structures


and dynamics of biological molecules such as proteins,
yielding clues to their functions

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100 Years of Magnetic Memories

Although the technology is ubiquitous today, magnetic


recording had a sluggish start. The underlying science was
something of a mystery, applications were slow to emerge,
and business and politics stifled development.

The Amateur Scientist

Floating A Challenge

Mathematical Recreations

Resurrection Shuffle

Oct 1998

Galaxies behind the Milky Way

Over a fifth of the universe is hidden from view, blocked by


dust and stars in the disk of our galaxy. But over the past few
years, astronomers have found ways to peek through the
murk

Designer Estrogens

These compounds - also called SERMs - have evolved from


mere laboratory curiosities into drugs that hold promise for
preventing several major disorders in women

Secrets of the Slime Hag

Loathsome though they may seem, hagfishes may also


resemble the earliest animals to have a braincase - making
them even older than the first animals to develop a backbone

The Asymmetry between Matter and


Antimatter

In 1999 new accelerators will start searching for violations in


a fundamental symmetry of nature, throwing open a window
to physics beyond the known

The Artistry of Microorganisms

Colonies of bacteria or amoebas form complex patterns that


blur the boundary between life and nonlife

Simon Newcomb: Astronomer with an


Attitude

The most celebrated American astronomer of the late 19th


century advocated broad social and cultural reforms based on
the use of scientific method

Computer Security and the Internet

This past February hackers reached through the Internet to


break into the computer networks at various U.S. Air Force
and Navy sites.

Port scanners, core dumps and buffer overflows are but a few
How Hackers Break In... and How They
of the many weapons in every sophisticated hacker's arsenal.
Are Caught
Still, no hacker is invincible
How Computer Security Works

Three types of safeguards offer a formidable defense against


Internet intruders

Cryptography for the Internet

E-mail and other information sent electronically are like


digital postcards - they afford little privacy. Well-designed
cryptography systems can ensure the secrecy of such
transmissions.

The Case against Regulating Encryption One of the pioneers of computer security says the U.S.
Technology
government should keep its hands off cryptography
The Amateur Scientist

Home Movies of an Invisible World

Mathematical Recreations

Playing with Chocolate

Sep 1998

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Preserving the Laetoli Footprints (Part


1)

The discovery of hominid footprints in East Africa reshaped


the study of human origins. Now conservators have protected
the fragile tracks from destruction

Preserving the Laetoli Footprints (Part


2)

The discovery of hominid footprints in East Africa reshaped


the study of human origins. Now conservators have protected
the fragile tracks from destruction

The Footprint Makers: An Early View

I worked on my painting of the Laetoli footprint makers


during the early fall of 1978, shortly after the discovery of the
hominid trackway.

The Laetoli Diorama

Only very rarely does the fossil record provide evidence of an


actual event in human prehistory.

Weightlessness and the Human Body

The effects of space travel on the body resemble some of the


conditions of aging. Studying astronauts' health may improve
medical care both in orbit and on the ground

Attention-Deficit Hyperactivity
Disorder

A new theory suggests the disorder results from a failure in


self-control. ADHD may arise when key brain circuits do not
develop properly, perhaps because of an altered gene or
genes

Making New Elements

Three new elements-110, 111 and 112-have been produced


over the past several years. Scientists are now struggling to
create 113 and 114. How many elements can they add to the
periodic table?

The Evolution of the Periodic System

From its origins some 200 years ago, the periodic table has
become a vital tool for modern chemists

The Oort Cloud

On the outskirts of the solar system swarms a vast cloud of


comets, influenced almost as much by other stars as by our
sun. The dynamics of this cloud may help explain such
matters as mass extinctions on Earth

Thermophotovoltaics

Semiconductors that convert radiant heat to electricity may


prove suitable for lighting remote villages or powering
automobiles

The Amateur Scientist

Spooling the Stuff of Life

Mathematical Recreations

Counting the Pyramid Builders

Aug 1998
Fusion and the Z Pinch

A device called the Z machine has led to a new way of


triggering controlled fusion with intense nanosecond bursts of
x-rays

Low-Back Pain

Low-back pain is at epidemic levels. Although its causes are


still poorly understood, treatment choices have improved,
with the body's own healing power often the most reliable
remedy

Computing with DNA

The manipulation of DNA to solve mathematical problems is


redefining what is meant by "computation"

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Monitoring and Controlling Debris in


Space

The path from Sputnik to the International Space Station has


been littered with high-tech refuse, creating an environmental
problem in outer space

A Quarter-Century of Recreational
Mathematics

The author of "Scientific American"'s column "Mathematical


Games" from 1956 to 1981 recounts 25 years of amusing
puzzles and serious discoveries

Irrigating Crops with Seawater

As the world's population grows and freshwater stores


become more precious, researchers are looking to the sea for
the water to irrigate selected crops

Microdiamonds

These tiny, enigmatic crystals hold promise both for industry


and for the study of how diamond grows

The Philadelphia Yellow Fever


Epidemic of 1793

One of the first major epidemics of the disease in the U.S., it


devastated America's early capital. It also had lasting
repercussions for the city and country

The Amateur Scientist

Building a Consciousness of Streams

Mathematical Recreations

Monks, Blobs and Common Knowledge

Jul 1998
The Mars Pathfinder Mission

Last summer the first ever Mars rover found in situ evidence
that the Red Planet may once have been hospitable to life

The Split Brain Revisited

Groundbreaking work that began more than a quarter of a


century ago has led to ongoing insights about brain
organization and consciousness

The Single-Atom Laser

A new type of laser that harnesses the energy of individual


atoms reveals how light interacts with matter

Mating Strategies in Butterflies

Butterflies meet, woo and win their mates using seductive


signals and clever strategies honed by evolution

Lon Foucault

Celebrated for his pendulum experiment in 1851, Foucault


also produced decisive evidence against the particle theory of
light, invented the gyroscope, perfected the reflecting
telescope and measured the sun's distance

Defeating AIDS: What Will It Take?

Ten years ago, when "Scientific American" published an issue


devoted to AIDS (the acquired immunodeficiency syndrome),
scientists knew that the disease, first identified in 1981, was
caused by HIV (the human immunodeficiency virus).

HIV 1998: The Global Picture

Worldwide, the populations most affected by the AIDS virus


are often the least empowered to confront it effectively

Improving HIV Therapy

Today's optimal treatments can work magic, but they are


costly and onerous and do not work for everyone. What
might the future bring?

How Drug Resistance Arises

When anti-HIV therapy fails to keep HIV levels suppressed,


the cause is often viral resistance to at least one of the drugs
being administered.

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Viral-Load Tests Provide Valuable


Answers

In the early 1990s tests that could accurately detect the


amount of HIV in a patient's blood finally became available.

When Children Harbor HIV

HIV infection is particularly difficult to combat in the young

Preventing HIV Infection

Altering behavior is still the primary way to control the


epidemic

Unlike vaccines for many viruses, those for HIV may have to
HIV Vaccines: Prospects and Challenges go beyond generating antibodies. Devising approaches that
will fully activate the immune system is far from simple
Avoiding Infection After HIV Exposure

Treatment may reduce the chance of contracting HIV


infection after a risky encounter

Coping With HIV's Ethical Dilemmas

The issues are many and thorny

The Amateur Scientist

A Year for the Oceans

Mathematical Recreations

The Bellows Conjecture

Jun 1998
The Neurobiology of Depression

The search for biological underpinnings of depression is


intensifying. Emerging findings promise to yield better
therapies for a disorder that too often proves fatal

A New Look at Quasars

Recent observations from the Hubble Space Telescope may


reveal the nature and origin of quasars, the mysterious
powerhouses of the cosmos

Shrimp Aquaculture and the


Environment

An adviser to shrimp producers and an environmentalist


present a prescription for raising shrimp responsibly

Quantum Computing with Molecules

By taking advantage of nuclear magnetic resonance,


scientists can coax the molecules in some ordinary liquids to
serve as an extraordinary type of computer

Gravity Gradiometry

A formerly classified technique used to navigate ballisticmissile submarines now helps geologists search for resources
hidden underground

Alcohol in the Western World

The role of alcohol in Western civilization has changed


dramatically during this millennium. Our current medical
interpretation of alcohol as primarily an agent of disease
comes after a more complex historical relationship

Defibrillation: The Spark of Life

In the 50 years since doctors first used electricity to restart


the human heart, we have learned much about defibrillators
and little about fibrillation

The Amateur Scientist

Waiter, There's a Hair in My Hygrometer

Mathematical Recreations

What a Coincidence!

May 1998

Six Months on Mir

As the Shuttle-Mir program draws to a close, a veteran NASA


astronaut reflects on her mission on board the Russian
spacecraft and the implications for the International Space
Station

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How Cicadas Make Their Noise

The loudest known insects, male cicadas are designed for


sound. Their internal instrument is surprisingly complex

The Genetics of Cognitive Abilities and


Disabilities

Investigations of specific cognitive skills can help clarify how


genes shape the components of intellect

Television's Bright New Technology

The plasma display panel is finally making good on a


decades-old promise: a big, bright screen so thin it can be
hung on a wall. But mainstream success requires that
engineers find a way to get prices down from the current
$11,000

Digital Television: Here at Last

After a long and contentious process, a digital standard in the


U.S. has finally emerged. It will soon replace today's
antiquated television system

Japanese Temple Geometry

During Japan's period of national seclusion (1639-1854),


native mathematics thrived, as evidenced in "sangaku"wooden tablets engraved with geometry problems hung under
the roofs of shrines and temples

A Calculus of Risk

Financial engineering can lessen exposure to the perils of


running a multibillion-dollar business or a small household.
But mathematical models used by this discipline may present
a new set of hazards

The Amateur Scientist

Sensing Subtle Tsunamis

Mathematical Recreations

Cementing Relationships

Apr 1998
Cosmic Antimatter

Antiparticles are rare and maddeningly elusive. But they may


hold clues to some of the mysteries of astrophysics

Post-Polio Syndrome

Decades after recovering much of their muscular strength,


survivors of paralytic polio are reporting unexpected fatigue,
pain and weakness. The cause appears to be degeneration of
motor neurons

Science in Pictures: The Earliest Views

Re-creating the experiments of pioneering microscopists


reveals what they actually saw with their simple, single-lens
instruments

How Females Choose Their Mates

Females often prefer to mate with the most flamboyant


males. Their choice may be based on a complex interaction
between instinct and imitation

Laser Scissors and Tweezers

Researchers are using lasers to grasp single cells and tinier


components in vises of light while delicately altering the held
structures. These lasers offer new ways to investigate and
manipulate cells

Wireless Technologies

Special Report

New Satellites for Personal


Communications

Fleets of satellites will soon make it possible to reach


someone anywhere on the earth, using nothing more than a
small handset

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Telecommunications for the 21st


Century

Systems based on satellites and high-altitude platforms will


merge with optical-fiber and terrestrial wireless networks to
provide global, high data-rate, mobile communications

Terrestrial Wireless Networks

Seamless switching between networks will draw users to


wireless data services. A working model is now in operation

Moving beyond Wireless Voice Systems

Cell phones are but one application of wireless


communications. The technology also enables accurate
position determination and the monitoring of remote sites

Spread-Spectrum Radio

Dicing information into digital bundles and transmitting them


at low power over different frequencies can enable millions
of people to send and receive simultaneously

The Amateur Scientist

Making Experiments out of Thin Air

Mathematical Recreations

Repealing the Law of Averages

Mar 1998
The Bose-Einstein Condensate

Three years ago in a Colorado laboratory, scientists realized a


long-standing dream, bringing the quantum world closer to
the one of everyday experience

The Challenge of Antibiotic Resistance

Certain bacterial infections now defy all antibiotics. The


resistance problem may be reversible, but only if society
begins to consider how the drugs affect "good" bacteria as
well as "bad"

Nanolasers

Semiconductor lasers have shrunk to dimensions even smaller


than the wavelength of the light they emit. In that realm,
quantum behavior takes over, enabling more efficient and
faster devices

Animating Human Motion

Computer animation is becoming increasingly lifelike. Using


simulation, a technique based on the laws of physics,
researchers have created virtual humans who run, dive,
bicycle and vault

The Caiman Trade

The contraband trade in caiman skins shows how "sustainable


utilization" of endangered species fails to sustain them

Preventing the Next Oil Crunch

Enough oil remains in the earth to fill the reservoir behind


Hoover Dam four times over-and that's just counting the
fraction of buried crude that is relatively easy to recover and
refine.

The End of Cheap Oil

Global production of conventional oil will begin to decline


sooner than most people think, probably within 10 years

Mining for Oil

More oil is trapped in Canadian sands than Saudi Arabia


holds in its reserves. The technology now exists to exploit this
vast resource profitably

Oil Production in the 21st Century

Recent innovations in underground imaging, steerable drilling


and deepwater oil production could recover more of what lies
below

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Liquid Fuels from Natural Gas

Natural gas is cleaner and more plentiful than oil. New ways
to convert it to liquid form may soon make it just as cheap
and convenient to use in vehicles

The Amateur Scientist

The Pleasures of Pond Scum

Mathematical Recreations

Glass Klein Bottles

Feb 1998
The Origin of Birds and Their Flight

Anatomical and aerodynamic analyses of fossils and living


birds show that birds evolved from small, predatory dinosaurs
that lived on the ground

Scientists in Black

In a unique collaboration, scientists and intelligence officials


are working together to find out what the U.S. government's
vast secret archives can reveal about the earth

The Viking Longship

Long, narrow ships packed with warriors helped to make the


Vikings the dominant power in Europe for three centuries,
beginning in about A.D. 800

The Theory Formerly Known as Strings

The Theory of Everything is emerging as one in which not


only strings but also membranes and black holes play a role

The Search for Blood Substitutes

The threat of global shortages of blood and fears about


contamination have hastened attempts to find life-sustaining
alternatives.

Greenland Ice Cores: Frozen in Time

Ice, frozen in place for tens of thousands of years, provides


scientists with clues to past-and future-climate

Everyday Exposure to Toxic Pollutants

Environmental regulations have improved the quality of


outdoor air. But problems that persist indoors have received
too little attention

The Amateur Scientist

Bird-Watching by the Numbers

Mathematical Recreations

Tight Tins for Round Sardines

Jan 1998
The Architecture of Life

A universal set of building rules seems to guide the design of


organic structures-from simple carbon compounds to complex
cells and tissues

Burial of Radioactive Waste under the


Seabed

Although the notion troubles some environmentalists, the


disposing of nuclear refuse within oceanic sediments merits
consideration

Bacterial Gene Swapping in Nature

Genes travel between independent bacteria more often than


once was assumed. Study of that process can help limit the
risks of releasing genetically engineered microbes into the
environment

The Ulysses Mission

The first space probe to be sent on a "polar" trajectory has


made some remarkable discoveries on its first orbit around
the sun

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Lise Meitner and the Discovery of


Nuclear Fission

One of the discoverers of fission in 1938, Meitner was at the


time overlooked by the Nobel judges. Racial persecution, fear
and opportunism combined to obscure her contributions

Picosecond Ultrasonics

Brief pulses of high-frequency sound allow experimenters to


probe connections inside a computer chip

The Placebo Effect

Colds, asthma, high blood pressure and heart disease are


among the many conditions that can respond to treatment
with a placebo. Should doctors be prescribing sugar pills?

Leonardo and the Invention of the


Wheellock

Leonardo da Vinci's notebooks are full of inventions, from


intricate gun parts to bicycles to automobiles. But were any
of Leonardo's many creations actually made during his
lifetime?

The Amateur Scientist

A Kitchen Centrifuge

Mathematical Recreations

Double Bubble, Toil and Trouble

Dec 1997
Metal Clusters and Magic Numbers

Investigations of tiny lumps of metal can help bridge the gap


in physicists' understanding of the differences between
isolated atoms and bulk solids

The Case for Relic Life on Mars

A meteorite found in Antarctica offers strong evidence that


Mars has had - and may still have - microbial life

Williams Syndrome and the Brain

To gain fresh insights into how the brain is organized,


investigators are turning to a little known disorder

Tracking a Dinosaur Attack

The efforts of a sculptor and a paleontologist reveal details of


a 100-million-year-old skirmish

Exploiting Zero-Point Energy

Energy fills empty space, but is there a lot to be tapped, as


some propound? Probably not

Building the Biggest

Our age worships small things: the microchip, recombinant


genes, mechanical parts built at the molecular scale.

The Longest Suspension Bridge

The Akashi Kaikyo Bridge has broken many records and


weathered an earthquake--even while it is being completed

The World's Tallest Buildings

Malaysia's Petronas Twin Towers serve as both a cultural and


an economic symbol

Building a New Gateway to China

The largest public-works upgrade on earth calls for, among


other things, a new airport, two world-class bridges and two
submerged crossings of Victoria Harbor

Do We Still Need Skyscrapers?

The Industrial Revolution made skyscrapers possible. The


Digital Revolution makes them (almost) obsolete

The Amateur Scientist

Taking Back the Final Frontier

Mathematical Recreations

Cat's Cradle Calculus Challenge

Nov 1997
Mercury: The Forgotten Planet

Although one of Earth's nearest neighbors, this strange world


remains, for the most part, unknown

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Fermat's Last Stand

His most notorious theorem baffled the greatest minds for


more than three centuries. But after 10 years of work, one
mathematician cracked it

Taking Nuclear Weapons off


Hair-Trigger Alert

It is time to end the practice of keeping nuclear missiles


constantly ready to fire. This change would greatly reduce the
possibility of a mistaken launch

The Parasitic Wasp's Secret Weapon

Parasitic wasps must develop inside living caterpillars. They


survive this hostile environment by smuggling in a virus that
suppresses their host's immune system

Fighting Computer Viruses

Biological metaphors offer insight into many aspects of


computer viruses and can inspire defenses against them

Great Zimbabwe

For centuries, this ancient Shona city stood at the hub of a


vast trade network. The site has also been at the center of a
bitter debate about African history and heritage

Making Rice Disease Resistant

For the first time, scientists have used genetic engineering to


protect this essential crop from disease

The Amateur Scientist

Caught in a Wind Tunnel

Mathematical Recreations

The Lore and Lure of Dice

Oct 1997
Transportation's Perennial Problems

The congestion, accidents and pollution that plague modern


travel are hardly new. History and recent research suggest
they may remain intractable for generations to come

The Past and Future of Global Mobility

With growing wealth, people everywhere travel farther and


faster. That trend inevitably brings a shift in the dominant
transportation technologies

13 Vehicles That Went Nowhere

Perhaps "nowhere" is too harsh. But all these transportation


concepts - however brilliant or eccentric - fell far short of
their enthusiasts' great hopes.

Hybrid Electric Vehicles

They will reduce pollution and conserve petroleum. But will


people buy them, even if the vehicles have astounding fuel
efficiency?

Flywheels in Hybrid Vehicles

A rapidly spinning flywheel combines with a gas-turbine


engine to power a novel hybrid electric vehicle

Automated Highways

Cars that drive themselves in tight formation might alleviate


the congestion now plaguing urban freeways

Unjamming Traffic with Computers

Insights gleaned from realistic simulations are already moving


from computer screens to asphalt

Now That Travel Can Be Virtual, Will


Congestion Virtually Disappear?

The idea that telecommunications technology could substitute


for travel dawned on people soon after the invention of the
telephone.

Driving to Mach 1

"Jetmobiles" try to go supersonic

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Speed versus Need

Rugged mountain climbers, bamboo rigs built for two, threespeeds with banana seats-bicycles, in their many forms, exist
the world over.

How High-Speed Trains Make Tracks

In Europe and Japan, train manufacturers are gearing up to


achieve ultrafast speeds routinely, without relying on
levitation

Fast Trains: Why the U.S. Lags

The reasons are more political than technological

Maglev: Racing to Oblivion?

Two years ago the world's only magnetically levitated train in


commercial service shut down.

Straight Up into the Blue

Tiltrotors, which take off like a helicopter but fly like an


airplane, will soon make their military debut. Can civilian
applications be far behind?

The Lure of Icarus

With new designs and materials, human-powered fliers


challenge the distance record

A Simpler Ride into Space

Technological advances may allow rockets of the next


century to operate much as aircraft do today. That change
might cut the cost of reaching orbit by 10-fold

Faster Ships for the Future

New designs for oceangoing freighters may soon double their


speeds

Microsubs Go to Sea

Small, maneuverable, self-contained - these tiny submersibles


may someday take a human to the bottom of the sea

Elevators on the Move

Elevator technology is taking off in new directions, including


sideways

The Amateur Scientist

Recording the Sounds of Life

Mathematical Recreations

Two-Way Jigsaw Puzzles

Sep 1997

In Search of AIDS-Resistance Genes

A genetic trait that protects against AIDS has now been


uncovered, and others are emerging. The findings open
entirely new avenues for developing preventives and
therapies

The Discovery of the Top Quark

Finding the sixth quark involved the world's most energetic


collisions and a cast of thousands

Building Doors into Cells

With the help of recombinant DNA technology, researchers


have learned how to create artificial pores that might be used
to deliver drugs or act as biosensors to detect toxic chemicals.

Running on Water

The secret of the basilisk lizard's strategy lies in its stroke

Creating False Memories

Researchers are showing how suggestion and imagination can


create "memories" of events that did not actually occur

Life in the Provinces of the Aztec


Empire

The lives of the Aztec common people were far richer and
more complex than the official histories would have us
believe.

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Booming Sand

Though known for centuries, sound-producing sand remains


one of nature's more puzzling phenomena

The Amateur Scientist

Unraveling the Secrets of Monarchs

Mathematical Recreations

Empires and Electronics

Aug 1997
Mitochondrial DNA in Aging and
Disease

Defects in DNA outside the chromosomes - in cell structures


called mitochondria - can cause an array of disorders,
perhaps including many that debilitate the elderly

Lightning Control with Lasers

Scientists seek to deflect damaging lightning strikes using


specially engineered lasers

Lightning between Earth and Space

Scientists discover a curious variety of electrical activity


going on above thunderstorms

Space Age Archaeology

Remote-sensing techniques are transforming archaeology.


Excavations may become less essential as researchers explore
hidden sites and examine buried artifacts without unearthing
them

Glandular Gifts

The way to a katydid's heart is through her stomach

The Top-Secret Life of Lev Landau

KGB archives reveal that the Soviet genius co-authored an


anti-Stalin manifesto

The Machinery of Thought

Studies of the brains of monkeys and, more recently, of


humans are revealing the neural underpinnings of working
memory, one of the mind's most crucial functions

The Amateur Scientist

Getting a Charge out of Rain

Mathematical Recreations

Empires on the Moon

Jul 1997
Cave temples along the ancient Silk Road document the
cultural and religious transformations of a millennium.
China's Buddhist Treasures at Dunhuang
Researchers are striving to preserve these endangered statues
and paintings
Gamma-Ray Bursts

New observations illuminate the most powerful explosions in


the universe

Xenotransplantation

After struggling for decades with a shortage of donated


organs from cadavers, transplant surgeons may soon have
another source to tap

Strong Fabrics for Fast Sails

Composite fabrics first developed for the sails of racing


yachts may soon find use in parachutes and research balloons

Asbestos Revisited

Once considered safe enough to use in toothpaste, this unique


substance has intrigued people for more than 2,000 years

Global Population and the Nitrogen


Cycle

Feeding humankind now demands so much nitrogen-based


fertilizer that the distribution of nitrogen on the earth has
been changed in dramatic, and sometimes dangerous, ways

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Taking Computers to Task

Coming generations of computers will be more fun and


engaging to use. But will they earn their keep in the
workplace?

The Amateur Scientist

How-To's of Butterfly Rookeries

Mathematical Recreations

Squaring the Square

Jun 1997
Iran's Nuclear Puzzle

Rich in fossil-fuel resources, Iran is pursuing a nuclear power


program difficult to understand in the absence of military
motives

Configurable Computing

Computers that modify their hardware circuits as they


operate are opening a new era in computer design. Because
they can filter data rapidly, they excel at pattern recognition,
image processing and encryption

Early Hominid Fossils from Africa

A new species of "Australopithecus", the ancestor of


"Homo", pushes back the origins of bipedalism to some four
million years ago

Panoramas of the Seafloor

Modern sonar techniques map the continental margins of the


U.S. and reveal the richly varied scenery usually hidden
underwater

Searching for Digital Pictures

Computers that can reason about images may be able to pick


out distinct features of a person, place or object from
photograph archives

Making Gene Therapy Work: Table of


Contents

Special Report

Overcoming the Obstacles to Gene


Therapy

Treating disease by providing needed genes remains a


compelling idea, but clinical and basic researchers still have
much to do before gene therapy can live up to its promise

Nonviral Strategies for Gene Therapy

Many drawbacks of viral gene delivery agents might be


overcome by nonviral systems. Studies in patients suggest
these systems have potential as therapies and as vaccines

Gene Therapy for Cancer

Inserted genes could in theory arrest tumor growth or even


AIDS

Gene Therapy for the Nervous System

Inserting genes into brain cells may one day offer doctors a
way to slow, or even reverse, the damage from degenerative
neurological disease

What Cloning Means for Gene Therapy

The recently debuted technology for cloning is usually


discussed as a means of creating genetic copies of whole
adult individuals.

Bringing Schrdinger's Cat to Life

Recent experiments have begun to demonstrate how the


weird world of quantum mechanics gives way to the
familiarity of everyday experience

The Amateur Scientist

Getting Inside an Ant's Head

Mathematical Recreations

The Sifting Sands of Factorland

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May 1997
Divided We Fall: Cooperation among
Lions

Although they are the most social of all cats, lions cooperate
only when it is in their own best interest

Managing Human Error in Aviation

Mistakes by flight crews contribute to more than two thirds of


aviation accidents. Training to enhance team performance
may reduce potentially fatal errors

Integrins and Health

Discovered only recently, these adhesive cell-surface


molecules have quickly revealed themselves to be critical to
proper functioning of the body and to life itself

The Coming Climate

Meteorological records and computer models permit insights


into some of the broad weather patterns of a warmer world

New Chemical Tools to Create Plastics

Small molecular machines called metallocene catalysts have


revolutionized the industrial synthesis of valuable plastics

Galaxies in the Young Universe

By comparing distant primeval galaxies with older ones


nearby, astronomers hope to determine how galaxies form
and evolve

Seeking a Better Way to Die

As the U.S. Supreme Court ponders physician-assisted


suicide, health care providers strive to improve care of the
dying

The Amateur Scientist

When Hazy Skies Are Rising

Mathematical Recreations

Big Game Hunting in Primeland

Apr 1997
Can Sustainable Management Save
Tropical Forests?

Sustainability proves surprisingly problematic in the quest to


reconcile conservation with the production of tropical timber

Black Holes and the Information


Paradox

What happens to the information in matter destroyed by a


black hole? Searching for that answer, physicists are groping
toward a quantum theory of gravity

Out of Africa Again... and Again?

Africa is the birthplace of humanity. But how many human


species evolved there? And when did they emigrate?

Combinatorial Chemistry and New


Drugs

An innovative technique that quickly produces large numbers


of structurally related compounds is changing the way drugs
are discovered

How Erosion Builds Mountains

An understanding of how tectonic, erosional and climatic


forces interact to shape mountains permits clearer insights
into the earth's history

Extremophiles

These microbes thrive under conditions that would kill other


creatures. The molecules that enable extremophiles to
prosper are becoming useful to industry

The Science of Murphy's Law

Life's little annoyances are not as random as they seem: the


awful truth is that the universe is against you

Jules Verne, Misunderstood Visionary

Discovery of a long-lost novel reveals that, from the start, the


father of science fiction was gravely concerned with the
dangers of technology

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The Amateur Scientist

The Joys of Armchair Ornithology

Mathematical Recreations

Knight's Tours

Mar 1997
SOHO Reveals the Secrets of the Sun

A powerful new spacecraft, the Solar and Heliospheric


Observatory, or SOHO, is now monitoring the sun around the
clock, providing new clues about our nearest star

The Internet

Fulfilling the Promise

The Internet: Bringing Order From


Chaos

The Internet, as everybody with a modem now knows, has


fallen victim to its own success.

Searching the Internet

Combining the skills of the librarian and the computer


scientist may help organize the anarchy of the Internet

Going Digital

Electronic libraries will make today's Internet pale by


comparison. But building them will not be easy

Filtering Information On The Internet

Look for the labels to decide if unknown software and World


Wide Web sites are safe and interesting

Interfaces For Searching the Web

The rapid growth of the World Wide Web is outpacing


current attempts to search and organize it. New user
interfaces may offer a better approach

Websurfing Without a Monitor

When I hook up to the Internet to check out the news on


CNN, to peruse a colleague's latest paper or to see how
Adobe's stock price is doing, I leave the display of my laptop
turned off.

Multilingualism on the Internet

In recent years, American culture has increased its worldwide


influence through international trade and Hollywood
productions.

Trusted Systems

Devices that enforce machine-readable rights to use the work


of a musician or author may create secure ways to publish
over the Internet.

Preserving the Internet

An archive of the Internet may prove to be a vital record for


historians, businesses and governments

Psychiatry's Global Challenge

An evolving crisis in the developing world signals the need


for a better understanding of the links between culture and
mental disorders

Discovering Genes for New Medicines

By identifying human genes involved in disease, researchers


can create potentially therapeutic proteins and speed the
development of powerful drugs

Heike Kamerlingh Onne's Discovery of


Superconductivity

The turn-of-the-century race to reach temperatures


approaching absolute zero led to the unexpected discovery of
electric currents that flowed with no resistance

Plants That Warm Themselves

Some plants produce extraordinary heat when they bloom. A


few even regulate their temperature within narrow limits,
much as if they were warm-blooded animals

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The Rising Seas

Although some voice concern that global warming will lead to


a meltdown of polar ice, flooding coastlines everywhere, the
true threat remais difficult to gauge

Mathematical Recreations

Juniper Green

The Amateur Scientist

Algorithm of the Gods

Feb 1997
Immunotherapy for Cocaine Addiction

Newly developed compounds derived from the immune


system may help combat cocaine abuse by destroying the
drug soon after it enters the bloodstream

Satellite Radar Interferometry

From hundreds of kilometers away in space, orbiting


instruments can detect subtle buckling of the earth's crust

The Ghostliest Galaxies

Astronomers have found more than 1,000 "low-surfacebrightness" galaxies over the past decade, significantly
altering our views of how galaxies evolve and how mass is
distributed in the universe

The Lesser Known Edison

In addition to his famous inventions, Thomas Edison's fertile


imagination gave the world a host of little known
technologies, from talking dolls to poured-concrete houses

Why and How Bacteria Communicate

Bacteria converse with one another and with plants and


animals by emitting and reacting to chemical signals. The
need to "talk" may help explain why the microbes synthesize
a vast array of compounds

The Challenge of Large Numbers

As computer capabilities increase, mathematicians can better


characterize and manipulate gargantuan figures. Even so,
some numbers can only be imagined

The Benefits and Ethics of Animal


Research

Experiments on animals are a mainstay of modern medical


and scientific research. But what are the costs and what are
the returns?

Animal Research Is Wasteful and


Misleading

The use of animals for research and testing is only one of


many investigative techniques available.

Animal Research Is Vital to Medicine

Experiments using animals have played a crucial role in the


development of modern medical treatments, and they will
continue to be necessary as researchers seek to alleviate
existing ailments and respond to the emergence of new
disease.

Trends in Animal Research

Increased concern for animals, among scientists as well as the


public, is changing the ways in which animals are used for
research and safety testing

The Amateur Scientist

A Picture-Perfect Comet

Mathematical Recreations

Crystallography of a Golf Ball

Jan 1997
Cosmic Rays at the Energy Frontier

These particles carry more energy than any others in the


universe. Their origin is unknown but may be relatively

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nearby
Understanding Parkinson's Disease

The smoking gun is still missing, but growing evidence


suggests highly reactive substances called free radicals are
central players in this common neurological disorder

Tackling Turbulence with


Supercomputers

Computers only recently became powerful enough to


illuminate simple examples of this great classical problem. In
some cases, they will let engineers control it

Transgenic Livestock as Drug Factories

By introducing key human genes into mammals, biologists


can induce dairy animals to produce therapeutic proteins in
their milk

How the Blind Draw

Blind and sighted people use many of the same devices in


sketching their surroundings, suggesting that vision and touch
are closely linked

Scientists monitor a controlled deluge that was staged in the


Experimental Flooding in Grand Canyon early spring of 1996 solely for the benefit of the environment
in and around the Colorado River
The Einstein-Sziland Refrigerator

Two visionary theoretical physicists joined forces in the


1920s to reinvent the household refrigerator

Science versus Antiscience?

Movements lumped under the term "antiscience" have


disparate causes, and not all pose as much of a threat as has
been claimed

The Amateur Scientist

Catch a Comet by Its Tail

Mathematical Recreations

Alphamagic Squares

Dec 1996
The Specter of Biological Weapons

States and terrorists alike have shown a growing interest in


germ warfare. More stringent arms-control efforts are needed
to discourage attacks

Primordial Deuterium and the Big Bang

Nuclei of this hydrogen isotope formed in the first moments


of the big bang. Their abundance offers clues to the early
evolution of the universe and the nature of cosmic dark
matter

Creating Nanophase Materials

The properties of these ultrafine-grained substances, now


found in a range of commercial products, can be customengineered

Cell Suicide in Health and Disease

Cells can - and often do - kill themselves, in a process known


as apoptosis. This capacity is essential to the proper
functioning of the body; flawed regulation may lie behind
many diseases

Atmospheric Dust and Acid Rain

Emissions of acidic air pollutants have fallen dramatically.


Why is acid rain still a problem? Atmospheric dust may be
part of the answer.

A Cricket Robot

Can a simple electromechanical system perform a complex


behavior of a living creature? There was one sure way to find
out

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Daily Life in Ancient Egypt

Workmen and their families lived some 3,000 years ago in the
village now known as Deir el-Medina. Written records from
the unusually well educated community offer fascinating
descriptions of everyday activities

Why Freud Isn't Dead

Skeptics continue to challenge Sigmund Freud's ideas about


the mind. Yet no unquestionably superior theory or therapy
has rendered psychoanalysis completely obsolete

The Amateur Scientist

Dissecting the Brain with Sound

Mathematical Recreations

Cows in the Maze

Nov 1996
The Case for Electric Vehicles

New technological developments have put practical electric


cars within reach, but politics may slow the shift away from
internal-combustion engines

Immunity and the Invertebrates

The fabulously complex immune systems of humans and


other mammals evolved over hundreds of millions of years in sometimes surprising ways

Sharks and the Origins of Vertebrate


Immunity

Sharks, which have existed for as many as 450 million years,


offer glimpses of a distant period in the evolution of the
immune system.

Quantum Seeing in the Dark

Quantum optics demonstrates the existence of


interaction-free measurements: the detection of objects
without light - or anything else - ever hitting them

Global Climatic Change on Mars

Today a frozen world, Mars at one time may have had more
temperate conditions, with flowing rivers, thawing seas,
melting glaciers and, perhaps, abundant life

Can China Feed Itself?

Some surprisingly reasonable policy changes would enable


the world's largest nation to produce more food for its 1.2
billion citizens

Dyslexia

A new model of this reading disorder emphasizes defects in


the language-processing rather than the visual system. It
explains why some very smart people have trouble learning to
read

Rock Art in Southern Africa

Paintings and engravings made by ancestors of the San


peoples encode the history and culture of a society thousands
of years old

The Amateur Scientist

Much Ado about Nothing

Mathematical Recreations

A Guide to Computer Dating

Oct 1996
Single Mothers and Welfare

For the first time since the Great Depression, large numbers
of families are homeless. Recent welfare revisions will put
even more women and children on the stress.

Microbes Deep inside the Earth

Recently discovered microorganisms that dwell within the


earth's crust could reveal clues to the origin of life

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Friction at the Atomic Scale

Long neglected by physicists, the study of friction's


atomic-level origins, or nanotribology, indicates that the force
stems from various unexpected sources, including sound
energy

Controlling Computers with Neural


Signals

Electrical impulses from nerves and muscles can command


computers directly, a method that aids people with physical
disabilities

Ten Days under the Sea

Living underwater in the world's only habitat devoted to


science, six aquanauts studied juvenile corals and fought off
"the funk"

How an Underwater Habitat Benefits


Marine Science

Scuba divers joke that there are two ways to avoid


decompression sickness, the rare but dreaded "bends": don't
go down, or don't come up.

Charles Darwin and Associates,


Ghostbusters

When the scientific establishment put a spiritualist on trial,


the co-discoverers of natural selection took opposing sides

Confronting Science's Logical Limits

The mathematical models now used in many scientific fields


may be fundamentally unable to answer certain questions
about the real world. Yet there may be ways around these
problems

Sounding Out Science

Prince William Sound is recovering, seven years after the


"Exxon Valdez" disaster. But the spill's scientific legacy
remains a mess

The Amateur Scientist

Working in a Vacuum

Mathematical Recreations

Monopoly Revisited

Sep 1996
How Cancer Arises

An explosion of research is uncovering the long-hidden


molecular underpinnings of cancer - and suggesting new
therapies

How Cancer Spreads

Tumor cells roam the body by evading the controls that keep
normal cells in place. That fact offers clues to fighting cancer

Causes and Prevention

Many of the culprits most publicized as causes of cancer


actually account for a relatively small fraction of deaths. The
good news: we can do more to protect ourselves. And a
growing area of study - chemoprevention - is attempting to
make the task easier.

What Causes Cancer?

The top two causes - tobacco and diet - account for almost
two thirds of all cancer deaths and are among the most
correctable

Strategies For Minimizing Cancer Risk

Simple, realistic preventive measures could save hundreds of


thousands of lives every year in developed countries alone

Chemoprevention of Cancer

Someday people should be able to avoid cancer or delay its


onset by taking specially formulated pills or foods

Is Hormone Replacement Therapy a


Risk?

Thanks to advances in public health and medicine, the


average American woman will be postmenopausal for about

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one third of her life.

Toward Earlier Detection

New technology promises not only to detect cancers earlier


and more accurately but also to catch tumors in their
precancerous state, when the disease still might be prevented
outright. The same basic instruments should help physicians
to distinguish patients who need minimal treatment from
those who need the most aggressive interventions.

Advances in Cancer Detection

Tests to look for the presence of a tumor before any


symptoms appear may save more lives than new drug
therapies do

Advances in Tumor Imaging

New tools yield a three-dimensional view inside the body and


automated advice on interpreting the anatomical landscape

Should Women in Their 40s Have


Mammograms?

For at least four years now, breast cancer specialists have


been heatedly arguing among themselves about whether
women in their forties benefit from having routine
mammograms.

Does Screening for Prostate Cancer


Make Sense?

Since 1990 the reported number of new cases of prostate


cancer has tripled, from fewer than 100,000 annually to an
estimated 317,000 this year.

Improving Conventional Therapy

The mainstays of cancer treatment - surgery, radiation and


chemotherapy - are being refined and combined in ways that
can help patients enjoy longer, more fulfilling lives.

Advancing Current Treatments for


Cancer

Surgery, radiation and chemotherapy can now cure many


cases of cancer. Future methods will be even more effective

When are Bone Marrow Transplants


Considered?

Bone marrow transplants can help to compensate for the


damaging effects of intense chemotherapy.

Twelve Major Cancers

The pages that follow provide facts and figures about the 12
cancers that affect the most Americans (excluding basal cell
and squamous cell skin cancers, which are very common but
rarely fatal).

Therapies of the Future

Fascinating new approaches to treatment would combat


cancers without the devastating side effects of many current
therapies. Some capitalize on insights into how the immune
system might be enlisted to destroy malignancies. Others are
based on detailed knowledge of how tumors grow and spread.

Immunotherapy for Cancer

As knowledge about the immune system grows, scientists are


devising ways, using the body's own defenses, to attack
cancer

New Molecular Targets for Cancer


Therapy

Investigators are exploiting the characteristic molecular


abnormalities of cancers in new approaches to treatment

Fighting Cancer by Attacking Its Blood


Supply

By interfering with the expanding network of blood vessels in


tumors, researchers hope to cut off the underlying support
system

Living with Cancer (Introduction)

There are ways to cope successfully with the physical,


psychological and practical challenges of the disease.

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Resources are available to patients who know where to look.


Even pain can usually be controlled - if caregivers award the
problem the attention it deserves.
Cancer's Psychological Challenges

Cancer patients today have many options for easing distress.


These interventions may not prolong life, but they can
improve its quality

Alternative Cancer Treatments

Miraculous cures are a myth, but some regimens may well


improve the quality of life for patients

Controlling the Pain of Cancer

Despite enormous advances in treating pain, many cancer


patients still suffer needlessly. Some simple practices can
make a difference

What Are Obstacles to Ideal Care?

Many patients do not know that being in a clinical trial is an


option.

Finding More Information

Fortunately, access to incisive knowledge about cancer and


its treatment is easier to obtain than ever before.

The Amateur Scientist

The Pleasures of Exploring Ponds

Mathematical Recreations

The Interrogator's Fallacy

Aug 1996
Smart Cards

As potential applications grow, computers in the wallet are


making unobtrusive inroads

The Stellar Dynamo

Sunspot cycles - on other stars - are helping astronomers


study the sun's variations and the ways they might affect the
earth

Gradients that Organize Embryo


Development

A few crucial molecular signals give rise to chemical


gradients that organize the developing embryo

Sands of the World

One of the most common elements on the earth's surface,


sand is also one of the most various

Probing High-Temperature
Superconductivity

Recent experiments exploiting subtle quantum effects yield


important clues about why some ceramics conduct electricity
without resistance

The Mystery of Lambic Beer

An ancient brewing technique produces a beverage so


complex that it is still yielding its secrets to organic chemists

Ring Bubbles of Dolphins

A number of bottlenose dolphins in Hawaii can create


shimmering, stable rings and helices of air as part of play

Gaining on Fat

As a costly epidemic of obesity spreads through the industrial


world, scientists are uncovering the biological roots of this
complex disease. The work offers tantalizing hope of new
ways to treat, and prevent, the health risks of excess weight

The Amateur Scientist

Detecting Micron-Size Movements

Mathematical Recreations

Shedding a Little Darkness

Jul 1996

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Next-Generation Compact Discs

A novel agreement among competing electronics companies


has delivered an innovative plan for compatible "DVD"
products - the first are due out this fall

Blue-Laser CD Technology

Coaxing semiconductor crystals into lasing blue light is no


easy task, but the rewards - among them, greater storage
space on optical disks - are well worth the wait

Sunlight and Skin Cancer

Although most skin cancers appear in older people, the


damage often begins decades earlier, when the sun's rays
mutate a key gene in a single cell

The Nature of Space and Time

Two relativists present their distinctive views on the universe,


its evolution and the impact of quantum theory

The Hidden World of Surgery

In his finely resolved images of surgery, a photographer sees


clues to who and what we are

The Mother of Mass Extinctions

Disaster struck 250 million years ago, when the worst


decimation in the earth's history occurred. Called the
end-Permian mass extinction, it marks a fundamental change
in the development of life

Who Owns Digital Works?

Computer networks challenge copyright law, but some


proposed cures may be as bad as the disease

Exoskeletal Sensors for Walking

To move their limbs, cockroaches, crabs and spiders rely on


organs in their exoskeletons that act as strain gauges. Their
method of locomotion could facilitate the design of
multilegged robots

The Amateur Scientist

Covert Observations of Nesting Sparrows

Mathematical Recreations

Arithmetic and Old Lace

Jun 1996
Semiconductor Subsidies

Did the U.S. government spend more than $700 million to


achieve a goal that might have been attained for much less?

Training the Olympic Athlete

Sports science and technology are today providing elite


competitors with the tiny margins needed to win in
world-class competition

Science in the Sky

The International Space Station will be the most expensive


object ever built. Although many scientists oppose the
grandiose scheme, its political momentum now appears
unstoppable

Can Nuclear Waste Be Stored Safely at


Yucca Mountain?

Studies of the mountain's history and geology can contribute


useful insights but not unequivocal conclusions

The Reluctant Father of Black Holes

Albert Einstein's equations of gravity are the foundation of


the modern view of black holes; ironically, he used the
equations in trying to prove these objects cannot exist

The Art of Charles R. Knight

Long before the film "Jurassic Park", Knight's illustrations


brought dinosaurs to life in the public's mind.

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Taxoids: New Weapons against Cancer

The chemists who developed the cancer-fighting agent taxol


are creating a family of similar compounds that may one day
help combat the disease.

The Amateur Scientist

Homemade Microgram Electrobalances

Mathematical Recreations

Tales of a Neglected Number

May 1996
The Horror of Land Mines

Land mines kill or maim more than 15,000 people each year.
Most victims are innocent civilians. Many are children. Still,
mines are planted by the thousands every day

The Kuiper Belt

Rather than ending abruptly at the orbit of Pluto, the outer


solar system contains an extended belt of small bodies

Uncovering New Clues to Cancer Risk

A growing discipline called molecular epidemiology is


attempting to find early biological signposts for heightened
risk of cancer. The research should enhance prevention of the
disease

Software for Reliable Networks

Techniques that enable distributed computing systems to


reorganize themselves can restore operation when one part
crashes

The Pursuit of Happiness

New research uncovers some anti-intuitive insights into how


many people are happy - and why

The Beluga Whales of the St. Lawrence


River

Although they are protected by law from hunters, these


whales must struggle to survive the threat of industrial
pollution

The Lost Technology of Ancient Greek


Rowing

The navies of classical Greece took advantage of the sliding


stroke, a technique that 19th-century competitive rowers later
reinvented

Hanford's Nuclear Wasteland

The U.S. is spending billions to clean up its nuclear weapons


complexes. At one of the most contaminated sites, no one
knows how much the project will cost, how long it will take
or how much good it will do

The Amateur Scientist

Detecting Natural Electromagnetic Waves

Mathematical Recreations

The Sculptures of Alan St. George

Apr 1996
Ten Years of the Chornobyl Era

The environmental and health effects of nuclear power's


greatest calamity will last for generations

The Birth of Complex Cells

Humans, together with all other animals, plants and fungi,


owe their existence to the momentous transformation of tiny,
primitive bacteria into large, intricately organized cells

Searching for Life on Other Planets

Life remains a phenomenon we know only on Earth. But an


innovative telescope in space could change that by detecting
signs of life on distant planets

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Smart Rooms

In creating computer systems that can identify people and


interpret their actions, researchers have come one step closer
to building helpful home and work environments

Alcohol in American History

National binges have alternated with enforced abstinence for


200 years, but there may be hope for moderation

Captured in Amber

The exquisitely preserved tissues of insects in amber reveal


some genetic secrets of evolution

Waiting for Breakthroughs

"Nanoists" envision global abundance emerging from the


manipulation of single atoms and molecules. But this
prophecy has been challenged by researchers who work at a
scale of billionths of a meter

The Amateur Scientist

The New Backyard Seismology

Mathematical Recreations

How Fair Is Monopoly?

Mar 1996
Urban Planning in Curitiba

A Brazilian city challenges conventional wisdom and relies


on low technology to improve the quality of urban life

Collisions with Comets and Asteroids

The chances of a celestial body colliding with the earth are


small, but the consequences would be catastrophic

The African AIDS Epidemic

In parts of sub-Saharan Africa, nearly 25 percent of the


population is HIV-positive as a result of heterosexual
transmission of the virus. Could lack of circumcision make
men in this region particularly susceptible?

Budding Vesicles in Living Cells

A transatlantic collaboration has uncovered the machinery


responsible for forming the tiny but essential containers, or
vesicles, that store proteins and shuttle them to and fro in
cells

The Art and Science of


Photoreconnaissance

In the 1950s and 1960s, photointerpreters devised ways of


extracting valuable information from recondite images.
Oftentimes, their work profoundly affected international
relations

Electrons in Flatland

Trapped in a two-dimensional plane, electrons can exhibit the


quantum Hall effect, a startling phenomenon now thought to
be intimately connected to superconductivity

Caribbean Mangrove Swamps

Despite their ubiquity and prominent position between land


and sea, these tropical ecosystems still hold countless
surprises for researchers

Vital Data

The Human Genome Project is producing a plethora of


information that will illuminate our hidden susceptibilities to
disease. The effort could transform medical science. But new
dangers are arriving, too

The Amateur Scientist

Exploring Chemical Bonds

Mathematical Recreations

Playing with Quads and Quazars

Feb 1996

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Malnutrition, Poverty and Intellectual


Development

Research into childhood nutrition reveals that a poor diet


influences mental development in more ways than expected.
Other aspects of poverty exacerbate the effects

The Global Positioning System

Two dozen satellites hovering thousands of miles out in space


are allowing people to locate themselves on the earth's
surface with remarkable precision

Seeing Underwater with Background


Noise

With a technique called acoustic-daylight imaging, sounds in


the sea can "illuminate" submerged objects, thereby creating
moving color pictures without sonar

Telomeres, Telomerase and Cancer

An unusual enzyme called telomerase acts on parts of


chromosomes known as telomeres. The enzyme has recently
been found in many human tumors and is being eyed as a
new target for cancer therapy

Colossal Galactic Explosions

Enormous outpourings of gas from the centers of nearby


galaxies may ultimately help explain both star formation and
the intergalactic medium

The Bacteria behind Ulcers

One half to one third of the world's population harbors


"Helicobacter pylori", "slow" bacteria that infect the stomach
and can cause ulcers and cancer there

The Loves of the Plants

Carl Linnaeus classified plants according to their


reproductive parts, endowing them as well with sex lives
reflecting 18th-century values and controversies

Quarks by Computer

Yearlong computations have helped to confirm the


fundamental theory behind quarks - and, using its principles,
even to identify a new particle

The Amateur Scientist

Growing Seedlings at Less Than 1 G

Mathematical Recreations

Proof of Purchase on the Internet

Jan 1996
The Real Threat of Nuclear Smuggling

Although many widely publicized incidents have been staged


or overblown, the dangers of even a single successful
diversion are too great to ignore

Caloric Restriction and Aging

Eat less, but be sure to have enough protein, fat, vitamins and
minerals. This prescription does wonders for the health and
longevity of rodents. Might it help humans as well?

Technology and Economics in the


Semiconductor Industry

Although the days of runaway growth may be numbered,


their passing may force chipmakers to offer more variety

Neural Networks for Vertebrate


Locomotion

The motions animals use to swim, run and fly are controlled
by specialized neural networks. For a jawless fish known as
the lamprey, the circuitry has been worked out

Cleaning Up the River Rhine

Intensive international efforts are reclaiming the most


important river in Europe

The Evolution of Continental Crust

The high-standing continents owe their existence to the


earth's long history of plate-tectonic activity

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Working Elephants

They earn their keep in Asia by providing an ecologically


benign way to harvest forests

Explaining Everything

A new symmetry, duality, is changing the way physicists think


about fundamental particles - or strings. It is also leading the
way to a Theory of Everything

The Amateur Scientist

Recording Nature's Sounds

Mathematical Recreations

Mother Worm's Blanket

Dec 1995
The Galileo Mission

From orbit around Jupiter, the Galileo spacecraft will take the
closest look ever at the planet and its natural satellites

Cystic Fibrosis

The genetic defects underlying this lethal disease have now


been shown to eliminate or hobble a critical channel through
which a constituent of salt enters and leaves cells

Science in Pictures

The Leaning Tower of Pisa The famous tower has been tilting
since the 12th century. Now engineers are using 20th-century
technology in hopes of saving the ancient landmark

Giant Earthquakes of the Pacific


Northwest

The danger of a very large earthquake striking the coast


between northern California and British Columbia proves
much greater than suspected

How Breast Milk Protects Newborns

Some of the molecules and cells in human milk actively help


infants stave off infection

The Puzzle of Conscious Experience

Neuroscientists and others are at last plumbing one of the


most profound mysteries of existence. But knowledge of the
brain alone may not get them to the bottom of it

Confidential Communication on the


Internet

Cryptography gives people the ability to authenticate the


identity of their correspondents, the first step in establishing
trust

Trends in Defense Technology

U.S. military planners hope to rely on improved versions of


the technologies tested in the Gulf War to help fight the next
Saddam Hussein. They may be preparing for the wrong
conflict

The Amateur Scientist

Measuring the Metabolism of Small Organisms

Mathematical Recreations

The Anthropomurphic Principle

Nov 1995
The World's Imperiled Fish

Wild fish cannot survive the onslaught of modern industrial


fishing. The collapse of fisheries in many regions shows the
danger plainly

The Brain's Immune System

It consists of cells called microglia that are normally


protective but can be surprisingly destructive. The cells may
contribute to neurodegenerative diseases and to the dementia
of AIDS

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Chaotic Climate

Global temperatures have been known to change


substantially in only a decade or two. Could another jump be
in the offng?

Holographic Memories

After more than 30 years, researchers are on the verge of


using holograms to store data in memories that are both fast
and vast

Charles Darwin

This newly rediscovered photograph appears to be the last


ever made of the great evolutionist

God's Utility Function

Humans have always wondered about the meaning of life.


According to the author, life has no higher purpose than to
perpetuate the survival of DNA

The Discovery of X-rays

One hundred years ago this month, Wilhelm Conrad Rntgen


cast the first x-ray images by chance

The Science of Juggling

Studying the ability to toss and catch balls and rings provides
insight into human coordination, robotics and mathematics

The Amateur Scientist

Measuring the Wind with Hot Metal

Mathematical Recreations

Ways to Tile Space with Knots

Oct 1995

Emerging Viruses

Hemorrhagic fever viruses are among the most dangerous


biological agents known. New ones are discovered every
year, and artificial as well as natural environmental changes
are favoring their spread

Companions to Young Stars

The surprising finding that even the youngest stars commonly


exist in sets of two or three has revised thinking about the
birth of star systems

Quantum-Mechanical Computers

Quantum-mechanical computers, if they can be constructed,


will do things no ordinary computer can

Demolition by Implosion

Detonation of small quantities of strategically placed


explosives can demolish an unwanted high-rise in a matter of
seconds

The Molecular Logic of Smell

Mammals can recognize thousands of odors, some of which


prompt powerful responses. Recent experiments illuminate
how the nose and brain may perceive scents

Science in Pictures

The raw visual and textual evidence of his imagination,


Edison's notebooks were the unrevealed talismans of the
inventor's career

Can Environmental Estrogens Cause


Breast Cancer?

The authors of a provocative hypothesis spell out their


reasons for suspecting that hormone-mimicking chemicals in
the environment contribute to many unexplained cases of
breast cancer

Trends in Social Science

Psychologists and others try to sidestep old pitfalls - both


political and scientific - as they apply evolutionary theory to
the clothed ape

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The Never-Ending Chess Game

Sep 1995
The Uncertainties of Technological
Innovation

Even the greatest ideas and inventions can flounder, whereas


more modest steps forward sometimes change the world

Information Technologies Table of


Content

Faster, more sophisticated data networks and computers will


dominate the systems people use to work and play.
Meanwhile intelligence will become a feature of everyday
machines. NOTE: No text.

Microprocessors in 2020

Every 18 months microprocessors double in speed. Within 25


years, one computer will be as powerful as all those in Silicon
Valley today

Wireless Networks

In the decade ahead, they will deliver personalized


communications to people on the go and basic service to
many who still lack telephones

All-Optical Networks

Fiber Optics will become more efficient as light waves


replace electrons for processing signals in communications
networks

Artificial Intelligence

A crucial storehouse of commonsense knowledge is now


taking shape

Intelligent Software

Programs that can act independently will ease the burdens


that computers put on people

Virtual Reality

VR will transform computers into extensions of our whole


bodies

Satellites For a Developing World

Satellites could provide universal access to the information


economy

Transportation Opener

Huge flying-wing aircarft, magnetically levitated trains and


driverless cars may carry passengers to their destinations,
while tiny spacecraft explore the solar system. NOTE: No
text.

High-Speed Rail: Another Golden Age

Neglected in North America but nurtured in Europe and


Japan, high-speed rail systems are a critical complement to
jets and cars

Built-in intelligence will let automobiles tune themselves to


The Automobile: Clean and Customized their drivers and cooperate to get through crowded traffic
systems safely
Evolution of the Commercial Airliner

Advances in materials, jet engines and cockpit diplays could


translate into less expensive and safer air travel

21st-Century Spacecraft

A fleet of cheap, miniaturized spacecraft may revive the


stalled Space Age, exploring the myriad tiny bodies of the
solar system

Why Go Anywhere?

Millions of people could be liberated from their vehicles

Medicine Opener

Many diseases may be cured with gene therapy, and damaged


organs may be repaired or replaced with tissue grown from

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cells in the laboratory. The new century should also see


innovative contraceptives, including, finally, some for men.
NOTE: No text.
Gene Therapy

Several hundred patients have already received treatment. In


the next century the procedure will be commonplace.

Artificial Organs

Engineering artificial tissue is the natural successor to


treatments for injury and disease. But the engineers will be
the body's own cells

Future Contraceptives

Vaccines for men and women will eventually join new


implants, better spermicides and stronger, thinnner condoms

An Improved Future?

Medical advances challenge thinking on living, dying and


being human

Buildings that repair themselves, machines that fit on the


Machines, Materials and Manufacturing head of a pin and local factories that make products to order
are just some of the possibilities. NOTE: No text.
Self-Assembling Materials

The smaller, more complex machines of the future cannot be


built with current methods: they must almost make
themselves

Engineering Microscopic Machines

Electronic fabrication processes can produce a data storage


device or a chemical factory on a microchip

Intelligent Materials

Inspired by nature, researchers are creating substances that


can anticipate failure, repair themselves and adapt to the
environment

Advanced Composites

After they first appeared in the 1960s, advanced composite


materials promised a brave new - not to mention light and
durable - future.

High-Temperature Superconductors

They conduct current without resistance more cheaply than


conventional superconductors can and are slowly finding
their way to widespread use

Robotics in the 21st Century

Automatons may soon find work as subservient household


help

Energy and Environment

The most crucial changes will come from attacking the waste
problems of industry, agriculture and energy production at a
fundamental level. NOTE: No text.

Solar Energy

Technology will allow radiation from the sun to provide


nonpolluting and cheap fuels, as well as electricity

Fusion

Energy derived from fused nuclei may become widely used


by the middle of the next century

Disposing of Nuclear Waste

At 3:49 P.M. on December 2, 1942, in a converted squash


court under the football stands at the University of Chicago, a
physicist slid back some control rods in the first nuclear
reactor and ushered in a new age.

The Industrial Ecology of the 21st


Century

A clean and efficient industrial economy would mimic the


natural world's ability to recycle materials and minimize

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waste
Technology for Sustainable Agriculture

The next green revolution needs to be sophisticated enough


to increase yields while also protecting the environment

Outline For an Ecological Economy

Countries can indeed prosper while protecting their


environment

Living with New Technologies

Technology will not solve all our problems. It may even


create some. But, despite its shortcomings, it continues to
offer us ever more ways to work, play, and order our lives.
NOTE: no text.

Technology Infrastructure

Industrial advances will depend on setting new standards

Designing the Future

Too frequently, product designers disregard the psychology of


the user

Digital Literacy

Multimedia will require equal facility in word, image and


sound

The Information Economy

How much will two bits be worth in the digital marketplace?

The Emperor's New Workplace

Information technology evolves more quickly than behavior

What Technology Alone Cannot Do

Technology will not provide us all with health, wealth and big
TVs

Mathematical Recreations

The Great Drain Robbery

Aug 1995

Recollections of a Nuclear War

Two nuclear bombs were dropped on Japan 50 years ago this


month. The author, a member of the Manhattan Project,
reflects on how the nuclear age began and what the post-cold
war future might hold

Tornadoes

The storms that spawn twisters are now largely understood,


but mysteries still remain about how these violent vortices
form

How HIV Defeats the Immune System

A plausible hypothesis suggests the immune devastation that


underlies AIDS stems from continuous - and dangerous evolution of the human immunodeficiency virus in the body

The Benefits of Background Noise

Stochastic resonance, the phenomenon by which background


noise boosts weak signals, is creating a buzz in physics,
biology and engineering

The Physiology of Decompression


Illness

For more than a century, researchers have known that


exposure to high pressure can injure or kill. Gradually, they
are beginning to understand the underlying mechanisms

Frog Communication

In striving to be heard by rivals and mates, these amphibians


have evolved a plethora of complex strategies

Comet Shoemaker-Levy 9 Meets Jupiter

Images of a comet that broke apart and plummeted into


Jupiter continue to dazzle astronomers a year afterward

Trends: Lost Science in the Third World

Many researchers in the developing world feel trapped in a


vicious circle of neglect and - some say - prejudice by

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publishing barriers they claim doom good science to oblivion


The Amateur Scientist

Detecting Signals with Noise

Jul 1995
The Problematic Red Wolf

Is the red wolf a species or a long-established hybrid of the


gray wolf and the coyote? Such distinctions may affect
ongoing efforts to save a variety of endangered species

Protecting the Greenback

Digital color systems can reproduce paper money with


disconcerting accuracy. The U.S. government's response is a
new series of notes

Treating Diabetes with Transplanted


Cells

The implants, islet cells of the pancreas, can potentially cure


many cases of diabetes. A prime obstacle to wide use - lack
of a safe way to avoid immune attacks on the grafts - now
seems to be crumbling

Light in the Ocean's Midwaters

Beneath the surface of the ocean, sunlight is gradually


extinguished, but the resulting darkness yields to a host of
bioluminescent creatures

Light in the Ocean's Midwaters

Fish such as hake, as well as some squids, arefast-moving,


wide-ranging predators, but they often linger near Ventana,
attracted to the lights of the ROV.

The Trebuchet

Recent reconstructions and computer simulations reveal the


operating principles of the most powerful weapon of its time

Cookstoves for the Developing World

Traditional wood, charcoal and coal stoves are used in


hundreds of millions of homes. Their redesign can have a
dramatic effect on energy usage, the environment and
community health

J. Robert Oppenheimer: Before the War

Although Oppenheimer is now best remembered for his


influence during World War II, he made many important
contributions to theoretical physics in the 1930s

Plastics Get Wired/Trends in Material


Science

By tailoring the electrical properties of conducting polymers,


researchers hope to render electronics a bit more organic

Mathematical Recreations

Election Fever in Blockvotia

Jun 1995
Debt and the Environment

Loans cause great human hardship, but their connection to


ecological troubles is hard to prove

Building World-Record Magnets

Packing the energy equivalent of a stick of dynamite,


powerful electromagnets around the globe compete to
advance our knowledge of materials science and physics

Hookworm Infection

It retards growth and intellectual development in millions of


children yet is largely ignored by researchers. New findings
suggest excellent possibilities for a vaccine

The Arithmetics of Mutual Help

Computer experiments show how cooperation rather than


exploitation can dominate in the Darwinian struggle for
survival

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Deciphering a Roman Blueprint

Scholarly detective work reveals the secret of a full-size


drawing chiseled into an ancient pavement. The "blueprint"
describes one of Rome's most famous buildings

Halo Nuclei

Nuclei having excess neutrons or protons teeter on the edges


of nuclear stability, known as drip lines. Under this stress,
some develop a halo

Kin Recognition

Many organisms, from sea squirts to primates, can identify


their relatives. Understanding how and why they do so has
prompted new thinking about the evolution of social behavior

Can science achieve a united theory of complex systems?


TRENDS IN COMPLEXITY STUDIES:
Even at the Santa Fe Institute, some researchers have their
From Complexity to Perplexity
doubts
The Amateur Scientist

Computing Bouts of the Prisoner's Dilemma

May 1995
The Global Tobacco Epidemic

Cigarette smoking has stopped declining in the U.S. and is


rising in other parts of the world. Aggressive marketing and
permissive regulations are largely to blame

Binary Neutron Stars

These paired stellar remnants supply exquisite confirmations


of general relativity. Their inevitable collapse produces what
may be the strongest explosions in the universe

Dendrimer Molecules

Chemists can now build fractal supermolecules. This new


class of polymers promises to be valuable in biotechnology
and environmental protection

The Ocean's Salt Fingers

A small-scale oddity in the way seawater mixes can have


large-scale consequences for the structure of the ocean

The Silicon Microstrip Detector

Produced with the same tools used to create integrated


circuits, these detectors recently helped to find the top quark
and are central to other crucial experiments

The Atomic Intrigues of Niels Bohr

Scandal is not usually linked with the name Niels Bohr;


genius and character are.

Did Bohr Share Nuclear Secrets?

Niels Bohr met with a Soviet agent in late 1945. Although


some have accused Bohr of divulging nuclear secrets, a
recently disclosed memo offers evidence to the contrary

What Did Heisenberg Tell Bohr about


the Bomb?

In 1941 Werner Heisenberg and Niels Bohr met privately in


Copenhagen. Almost two years later at Los Alamos, Bohr
showed a sketch of what he believed was Heisenberg's design
for a nuclear weapon

The Preservation of Past

Conservators are racing to save monuments threatened by


development, pollution, looting and neglect. In the process,
they are transforming the field of archaeology into a new
science

Mathematical Recreations

Fibonacci Forgeries

Apr 1995

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The Puzzle of Declining Amphibian


Populations

The number of frogs, toads and salamanders is dropping in


many areas of the world. The causes range from destruction
of their local habitats to global depletion of the ozone layer

Quest for the Limits of the Heliosphere

Four aging spacecraft are racing to the outer reaches of the


solar system. Soon they may break through the last barriers to
interstellar space

Machines That Learn from Hints

Machine learning improves significantly by taking advantage


of information available from intelligent hints

Studies of courtship and mating in the fruit fly offer a window


Understanding the Genetic Construction
on the ways genes influence the execution of complex
of Behavior
behaviors
The Art Historian's Computer

Riddles posed by ancient works of art fall to historical


analyses and electronic explorations

A Brief History of Infinity

The infinite has always been a slippery concept. Even the


commonly accepted mathematical view, developed by Georg
Cantor, may not have truly placed infinity on a rigorous
foundation

The Tapestry of Power in a


Mesopotamian City

Mashkan-shapir was for a brief time one of the most


important cities in the civilized world. Its remains challenge
traditional notions of power distribution in early urban society

The Price of Prevention

Policymakers frequently suggest that preventive medicine


pays for itself. In fact, studies now show that this claim is
rarely true. Still, prevention is often a worthy health
investment

The Amateur Scientist

Computerized Restoration of Juvenile Art

Mar 1995
Faster Evaluation of Vital Drugs

Traditional clinical trials may delay the availability of


lifesaving therapies. Regulators now attempt to balance speed
against the risk of errors

The Many Costs of Drug Testing

When researchers test a new drug, pressures from many


different constituencies coverage on the clinical trail.

Laser Control of Chemical Reactions

For years, chemists have sought to control reactions with


lasers - and have mostly failed. Success may come from
exploiting subtle quantum effects resulting from the
interaction of light and matter

An Efficient Swimming Machine

Instinctive control of vortices lets fish swim the way they do.
A robotic tuna has also managed it; boats and submarines
may be next

The Genetic Basis of Cancer

An accumulation of genetic defects can apparently cause


normal cells to become cancerous and cancerous cells to
become increasingly dangerous

Bonobo Sex and Society

The behavior of a close relative challenges assumptions about


male supremacy in human evolution

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Protein-Based Computers

Devices fabricated from biological molecules promise


compact size and faster data storage. They lend themselves to
use in parallel-processing computers, three-dimensional
memories and neural networks

Environmental Degradation in Ancient


Greece

Contrary to the view that the ancients lived in harmony with


their environment, archaeological and geologic evidence
shows that they often abused the land

Seeking the Criminal Element

Scientists are homing in on social and biological risk factors


that they believe predispose individuals to criminal behavior.
The knowledge could be ripe with promise - or rife with
danger

Mathematical Recreations

Turning the Tables Around

Feb 1995
Population, Poverty and the Local
Environment

As forests and rivers recede, a child's labor can become more


valuable to parents, spurring a vicious cycle that traps
families in poverty

Sonoluminescence: Sound into Light

A bubble of air can focus acoustic energy a trillionfold to


produce picosecond flashes of light. The mechanism eludes
complete explanation

Molecular Machines That Control


Genes

The activities of our genes are tightly regulated by elaborate


complexes of proteins that assemble on DNA. Perturbations
in the normal operation of these assemblies can lead to
diseases.

Manic-Depressive Illness and Creativity

Does some fine madness plague great artists? Several studies


now show that creativity and mood disorders are linked

Masers in The Sky

Interstellar gas clouds produce intense, coherent microwaves.


This radiation offers a glimpse of the size, content and
distance of objects that may otherwise be invisible

The History of Synthetic Testosterone

Testosterone has long been banned in sports as a


performance-enhancing drug. This use may soon be accepted
in medicine alongside other legitimate hormonal therapies

The Mid-Cretaceous Superplume


Episode

The earth has an erratic "heartbeat" that can release vast


amounts of heat from deep within the planet. The latest
"pulse" of the earth occurred 120 million years ago

Toward "Point One"

Gigabit chips are now in the laboratory. But the critical


technology needed for manufacturing smaller circuits
confronts diminishing returns

The Amateur Scientist

Producing Light from a Bubble of Air

Jan 1995
Ensuring the Longevity of Digital
Documents

The digital medium is replacing paper in a dramatic recordkeeping revolution. But such documents may be lost unless
we act now

The Prion Diseases

Prions, once dismissed as an impossibility, have now gained


wide recognition as extraordinary agents that cause a number

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of infectious, genetic and spontaneous disorders


Earth Before Pangea

The North American continent may be more nomadic than


any of its inhabitants

Elastic Biomolecular Machines

Synthetic chains of amino acids, patterned after those in


connective tissue, can transform heat and chemical energy
into motion

The Oldest Old

People in their late nineties or older are often healthier and


more robust than those 20 years younger.

The Birth and Disease of Nova V1974


Cygni

The brightest nova in 17 years answered many questions


during its life and raised more in death

Egil's Bones

An Icelandic saga tells of a Viking who had unusual,


menacing features, including a skull that could resist blows
from an ax. He probably suffered from an ailment called
Paget's disease

Better Than a Cure

The World Health Organization wants industry to step up its


efforts to develop new vaccines. Can big business and a
public health bureaucracy see eye to eye?

Mathematical Recreations

Daisy, Daisy, Give Me Your Answer, Do

Dec 1994
Improving Automotive Efficiency

Batteries and fuel cells? Cleaner air and reduced oil imports
can be won by redesigning conventional internal-combustionpowered vehicles

Fossils of The Flaming Cliffs

Mongolia's Gobi Desert contains one of the richest


assemblages of dinosaur remains ever found. Paleontologists
are uncovering much of the region's history.

Earth From Sky

Radar systems carried aloft by the space shuttle Endeavour


provide a new perspective of the earth's environment

The New Genetic Medicines

Synthetic strands of DNA are being developed as drugs.


Called antisense and triplex agents, they can potentially
attack viruses and cancers without harming healthy tissue

The Duality in Matter and Light

In quantum mechanics, objects can behave as particles or as


waves. Studies now emphasize that such complementary
features are more fundamental than has generally been
appreciated

Making Environmental Treaties Work

Many agreements aim to protect the global environment. But


actually making them do so requires innovative approaches

Caulerpa

This tropical alga is the world's largest single-celled organism.


Yet it differentiates into a complex structure of leaves, stems
and roots

Trends: The Speed of Write

Scientists now transmit reports of their research - from first


inspiration to final result - over electronic networks. Even
live experiments can be witnessed on-line. Publishers and
libraries may never be the same

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Measuring the Energy Drain on Your Car

Nov 1994
Cerebrospinal Meningitis Epidemics

A debilitating and often deadly disease, meningitis remains


common in many developing countries. New insights may
soon enable us to predict and control outbreaks

The Self-Reproducing Inflationary


Universe

Recent versions of the inflationary scenario describe the


universe as a self-generating fractal that sprouts other
inflationary universes

The Genetics of Flower Development

Flower cells learn which organs to become from genes that


convey positional information. A model based on just half a
dozen such genes can predict how mutations will affect floral
structure

Sci Pixs: Escher's Metaphors

The prints and drawings of M.C. Escher give expression to


abstract concepts of mathematics and science

Secure Distributed Computing

Networks and computer security often do not go well


together, but the developers of the Athena system have yet to
see their protocols fail

Why Children Talk to Themselves

Although children are often rebuked for talking to themselves


out loud, doing so helps them control their behavior and
master new skills

Resolving Zeno's Paradoxes

For millennia, mathematicians and philosophers have tried to


refute Zeno's paradoxes, a set of riddles suggesting that
motion is inherently impossible. At last, a solution has been
found

Big-Time Biology

Molecular biology is - not so quietly - evolving from a science


into an industry. Can it survive the transformation?

Mathematical Recreations

Playing Chess on a Go Board

Oct 1994

Life in the Universe

We comprehend the universe and our place in it. But there


are limits to what we can explain at present. Will research at
the boundaries of science reveal a special role for intelligent
life?

The Evolution of the Universe

Some 15 billion years ago the universe emerged from a hot,


dense sea of matter and energy. As the cosmos expanded and
cooled, it spawned galaxies, stars, planets and life

The Earth's Elements

The elements that make up the earth and its inhabitants were
created by an earlier generation of stars

The Evolution of the Earth

The formation of this planet and its atmosphere gave rise to


life, which shaped the earth's subsequent development. Our
future lies in interpreting this geologic past

The Origin of Life On Earth

Growing evidence supports the idea that the emergence of


catalytic RNA was a crucial early step. How that RNA came
into being remains unknown

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The Evolution of Life on the Earth

The history of life is not necessarily progressive; it is certainly


not predictable. The earths creatures have evolved through a
series of contingent and fortuitous events

The Search for Extraterrestrial Life

The earth remains the only inhabited world known so far, but
scientists are finding that the universe abounds with the
chemistry of life

The Emergence of Intelligence

Language, foresight, musical skills and other hallmarks of


intelligence are connected through an underlying facility that
enhances rapid movements

Will Robots Inherit The Earth

Yes, as we engineer replacement bodies and brains using


nanotechnology. We will then live longer, possess greater
wisdom and enjoy capabilities as yet unimagined

Sustaining Life On Earth

Hope for an environmentally sustainable future lies in


evolving institutions, technology and global concern

The Amateur Scientist

Building an Electronic Neuron

Sep 1994
Disarming Lyme Disease

Antibiotics are usually curative. A vaccine is in clinical trials.


Next on the research agenda: how to help people suffering
from chronic symptoms

Low-Energy Ways To Observe


High-Energy Phenomena

By observing interactions that are forbidden in the Standard


Model, physicists can peek at supersymmetric and other
happenings

The Aluminum Beverage Can

Produced by the hundreds of millions every day, the modern


can, robust enough to support the weight of an average adult,
is a tribute to precision design and engineering

The Machinery of Cell Crawling

When a cell crawls, part of its fluid cytoplasm briefly turns


rigid. This transformation depends on the orderly assembly
and disassembly of a protein scaffold

Solving The Paradox of Deep


Earthquakes

For decades, geophsicists have known that earthquakes


should not occur at depth inside the earth. But they do.
Finally, we know how and why these events happen

Privatizing Public Research

With the end of the cold war, national defense has given way
to international competitiveness as the theme for federal
support of research. As it now stands, the idea will probably
not work well

Bonaparte's invasion of Egypt brought French scientists and


The Scientific Importance of Napoleon's
engineers to the Nile. Their work, in turn, brought the
Egyptian Campaign
splendors of the Nile to Europe
Trends in Computing: Software's
Chronic Crisis

Despite 50 years of progress, the software industry remains


years - perhaps decades - short of the mature engineering
discipline needed to meet the demands of an information-age
society

Mathematical Recreations

A Subway Named Turing

Aug 1994

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Third World Submarines

The proliferation of submarines may be a threat to established


navies and regional stability, but to arms manufacturers it is a
market opportunity

Extreme Ultraviolet Astronomy

Observations at these wavelengths, once thought impossible,


are extending knowledge of the cosmos

Confocal Microscopy

For producing sharp two- or three-dimensional images with


light,this microscopic technique is unsurpassed. It can also be
applied for seeing deep inside the tissues of living specimens

Squids

(for superconducting quantum interference devices) are the


most sensitive detectors of magnetic fields. Their applications
range from diagnosis of brain tumors to tests of relativity

How Cells Produce Antigens

Cells alert the immune system to the presence of infections


by displaying molecular complexes made from bits of their
own proteins and those of invading organisms

Red Tides

Many experts believe these blooms of toxic algae have


recently become more prevalent, posing a greater threat to
human and marine health

The Eloquent Bones of Abu Hureya

The daily grind in an early Near Eastern agricultural


community left revealing marks on the skeletons of the
inhabitants

Trends In Women's Health: A Global


View

Improving women's health means overhauling attitudes


toward sex and addressing hidden epidemics, such as
domestic violence

The Amateur Scientist

Scanning Underwater Surfaces

Jul 1994
Agriculture for Developing Nations

The capital-intensive, highly mechanized Western model may


not suit every developing region. Systems of intensive
polyculture, exemplified by rice cultivation, may be better

The Scientific Legacy of Apollo

The retrieved lunar rocks have helped settle questions about


the moon's origin, its composition and even the early
conditions that affected life on the earth

Synthetic Self-Replicating Molecules

Molecules crafted in the laboratory can make copies of


themselves, "mutate," compete for resources and assemble,
giving a paradigm for life

Barriers to Drug Delivery in Solid


Tumors

Many tumors resist full penetration by anticancer agents.


Such resistance may help explain why drugs that eradicate
tumor cells in laboratory dishes often fail to eliminate
malignancies in the body

Manatees

These giant aquatic grazers outchewed their rivals in the New


World. Now humans, their sole enemy, hold the key to their
survival

Jean Henri Fabre

This reclusive entomologist became one of the most popular


educational authors of his day. A look at his greatest work
reveals both the underappreciated achievements and the
failings of his science

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Late Ice Age Hunting Technology

Cro-Magnon artisans designed many kinds of spearpoints. By


re-creating these weapons, we can better appreciate the
sophisticated skill ancient hunters possessed

Trends: In Neuroscience

What is consciousness? Can neurobiology explain it, or - as


some philosophers argue - does this most elusive and
inescapable of all phenomena lie beyond experiment's reach?

Mathematical Recreations

The Ultimate in Anty-Particles

Jun 1994
Was The Race To The Moon Real?

In 1961 President John F. Kennedy made the goal to be first


on the moon a matter of national honor. But were the Soviets
truly in the running?

The Classical Limit of an Atom

By creating ultralarge atoms, physicists hope to study how the


odd physics of the quantum world becomes the classical
mechanics of everyday experience

Emotion, Memory and the Brain

The neural routes underlying the formation of memories


about primitive emotional experiences, such as fear, have
been traced

Adaptive Optics

Technology developed during the cold war is giving new


capabilities to ground-based astronomical telescopes

Early Andean Cities

Some 3,800 years ago Pampa de las Llamas-Moxeke and


Taukachi-Konkan were carefully laid-out urban centers that
housed many hundreds of people

The Sensory Basis of the Honeybee's


Dance Language

Novel experiments, such as training bees to respond to


sounds and recruiting them using a robot, have ended several
debates surrounding the dance language

The Ethnobotanical Approach to Drug


Discovery

Medicinal plants discovered by traditional societies are


proving to be an important source of potentially therapeutic
drugs

Grading the Gene Tests

From just a snippet of DNA, geneticists can sometimes


forecast a patient's health. But ethical problems surrounding
this testing are as ominous as the diseases themselves.

The Amateur Scientist

Genetically Altering Escherichia coli

May 1994
Evidence for a Biological Influence in
Male Homosexuality

Two pieces of evidence, a structure within the human brain


and a genetic link, point to a biological component for male
homosexuality

The Biological Evidence Challenged

Even if genetic and neuroanatomical traits turn out to be


correlated with sexual orientation, causation is far from
proved

Bohm's Alternative to Quantum


Mechanics

This theory, ignored for most of the past four decades,


challenges the probabilistic, subjectivist picture of reality
implicit in the standard formulation of quantum mechanics

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How Interferons Fight Disease

They are not the cure-alls researchers once hoped they would
be, but they are providing therapy for a variety of infectious
illnesses and for some cancers

Chesley Bonestell's Astronomical


Visions

This artist's unique combination of technical knowledge and


graphic prowess brought astronomy alive and helped to
advance the manned spaceflight program

Directional Drilling

New techniques enable crews to drill around natural or


man-made obstructions for oil and gas. These same methods
are used to sample underground pollutants and bury service
lines

East Side Story: The Origin of


Humankind

The Rift Valley in Africa holds the secret to the divergence of


hominids from the great apes and to the emergence of human
beings

Aging Airways

The FAA struggles to replace its winking, blinking air-traffic


control equipment. But will the skies be safer? Can the
agency survive the effort intact?

Mathematical Recreations

How Many Guards in the Gallery?

Apr 1994
Trade, Jobs and Wages

Blaming foreign competition for U.S. economic ills is


ineffective. The real problems lie at home

Charge and Spin Density Waves

Electrons in some metals arrange into crystalline patterns that


move in concert, respond peculiarly to applied voltages and
show self-organization

Visualizing the Mind

Strategies of cognitive science and techniques of modern


brain imaging open a window to the neural systems
responsible for thought

Chemistry and Physics in the Kitchen

Bon apptit! Scientists are beginning to understand how chefs


accomplish their culinary masterpieces and are making
modest recipe suggestions of their own

The Dilemmas of Prostate Cancer

Do the risks of aggressive treatment for early prostate cancer


outweigh the benefits? This question is one of several
unresolved issues faced by those who treat, and those who
have, prostate cancer

Precious Metal Objects of the Middle


Sican

A Peruvian culture older than the Incas made unprecedented


use of gold and other metals. Studies of Sicn metalworking
techniques offer hints about this mysterious society

The Pioneer Mission to Venus

This multipart spacecraft spent 14 years scrutinizing the


atmosphere, clouds and environs of the nearest planet. The
results clarify the stunningly divergent evolutionary histories
of Venus and the earth

Trends In Biological Restoration

Can we rebuild it? The field of ecological restoration is


evaluating techniques to restore nature and is grappling with
definitions of success

The Amateur Scientist

The Kitchen as a Lab

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Mar 1994
Can the Growing Human Population
Feed Itself?

As human numbers surge toward 10 billion, some experts are


alarmed, others optimistic. Who is right?

The Earth's Mantle Below The Oceans

Samples collected from the ocean floor reveal how the


mantles convective forces shape the earths surface, create its
crust and perhaps even affect its rotation

Targeted Gene Replacement

Researchers can now create mice bearing any chosen


mutations in any known gene. The technology is
revolutionizing the study of mammalian biology

High-Speed Silicon-Germanium
Electronics

The author has helped create electronic devices that


outperform traditional silicon technology yet remain
compatible with standard manufacturing methods

The Quantum Physics of Time Travel

Common sense may rule out such excursions - but the laws of
physics do not

The Dynamics of Social Dilemmas

Individuals in groups must often choose between acting


selfishly or cooperating for the common good. Social models
explain how group cooperation arises - and why that behavior
can suddenly change

Frogs and Toads in Deserts

Amphibians seem unlikely desert denizens. But those living in


dry climes reveal a diverse and unusual array of adaptations
to life at the extremes

Wire Pirates

Consumers and entrepreneurs crowd onto the information


highway, where electronic bandits and other hazards await
them

Mathematical Recreations

The New Merology of Beastly Numbers

Feb 1994
The Future of American Defense

U.S. forces were shaped for conflict with a superpower. The


emerging multilateral world calls for a smaller, more flexible
and far less expensive military

Sulfate Aerosol and Climatic Change

Industrial emissions of sulfur form particles that may be


reflecting solar radiation back into space, thereby masking
the greenhouse effect over some parts of the earth

The Molecular Architects of Body


Design

Putting a human gene into a fly may sound like the basis for a
science fiction film, but it demonstrates that nearly identical
molecular mechanisms define body shapes in all animals

When Is Seeing Believing?

Digital technology for manipulating images has subverted the


certainty of photographic evidence

Liquid Mirrors

Light, liquid-mercury mirrors, which can potentially be made


much larger than glass mirrors, may enable astronomers to
construct enormous telescopes and see farther than ever
before

AIDS and the Use of Injected Drugs

The AIDS epidemic continues to grow among drug users who


inject. It could be curbed if governments more readily
adopted effective prevention programs

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The Terror Birds of South America

These huge, swift creatures were the dominant carnivores of


the continent for millions of years, until competitors drove
them into extinction

Particle Metaphysics

In the aftermath of the Superconducting Super Collider's


death, physicists are divided over how - or even whether they should continue their search for a unified theory of
nature

The Amateur Scientist

Making a Mirror by Spinning a Liquid

Jan 1994

Wetlands

These havens of biodiversity are often endangered because


they can be hard to identify. Understanding their variable
characteristics can lead to more successful conservation
efforts

The Search for Strange Matter

Between nucleus and neutron star stretches a desert devoid


of nuclear matter. Could strange quark matter fill the gap?

The Toxins of Cyanobacteria

These poisons, which periodically and fatally contaminate the


water supplies of wild and domestic animals, can also harm
humans. But they are being coaxed into doing good

Breaking Intractability

Problems that would otherwise be impossible to solve can


now be computed, as long as one settles for what happens on
the average

Animal Sexuality

Animals have evolved a range of mechanisms to determine


whether an individual takes on masculine or feminine traits.
Cross-species comparisons offer some surprising insights into
the nature of sexuality

World Linguistic Diversity

The ancestor of each language was taken to its current


territory by pioneers, farmers, traders or a conquering elite.
Multidisciplinary studies are clarifying their respective roles

The First Data Networks

The optical telegraph is almost forgotten. Two centuries ago it


moved messages over hundreds of kilometers in a few
minutes

Trends: A War Not Won

Despite dramatic scientific gains, cancer remains an


undaunted killer

Mathematical Recreations

Knots, Links and Videotape

Dec 1993
The Fertility Decline in Developing
Countries

Family size is decreasing in many Third World countries. The


reasons provide the key to slowing population growth

The Compton Gamma Ray Observatory

A steady stream of data from this orbiting observatory is


painting a portrait of a dynamic and often enigmatic cosmos

MHC Polymorphism and Human


Origins

The diversity of human tissue types was generated long


before Homo sapiens emerged

Africanized Bees in the U.S.

Africanized honeybees have reached the U.S. from points


south. As more of them arrive, they will certainly wreak some

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havoc but perhaps not the type their "killer bee" nickname
would imply

Drugs by Design

Structure-based design, an innovative approach to developing


drugs, has recently spawned many promising therapeutic
agents, including several now in human trials for treating
AIDS, cancer and other diseases

Coupled Oscillators and Biological


Synchronization

A subtle mathematical thread connects clocks, ambling


elephants, brain rhythms and the onset of chaos

The Death Cults of Prehistoric Malta

New archaeological excavations reveal that as the ancient


island societies suffered from environmental decline, they
developed an extreme religious preoccupation with life and
death

Current Events

Now that the blizzard of hype has stopped, workers are


gradually realizing the promise of high-temperature
superconductors

The Amateur Scientist

Electronic Fireflies

Nov 1993
The Case for Free Trade

Environmentalists are wrong to fear the effects of free trade.


Both causes can be advanced by imaginative solutions

The Perils of Free Trade

Economists routinely ignore its hidden costs to the


environment and the community

Chemical Signaling in the Brain

Studies of acetylcholine receptors in the electric organs of


fish have generated critical insights into how neurons in the
human brain communicate with one another

X-Ray Binaries

In these systems, ultradense neutron stars feed on their more


sedate companions. Such stellar cannibalism produces
brilliant outpourings of x-rays and drastically alters the
evolution of both stars

The Art of Boris Artzybasheff

A compelling mid-20th century vision of the machines of war


and peace

High-Power Electronics

A new generation of silicon switches enables power grids to


meet the needs of utility customers with high efficiency and
reliability

Ancient DNA

Genetic information that had seemed lost forever turns out to


linger in the remains of long-dead plants and animals.
Evolutionary change can at last be observed directly

Trends in the Sociology of Science

Despite decades of struggle, women retain a small minority in


the scientific commmunity

Mathematical Recreations

Fermat's Last Time-Trip

Oct 1993
Clearing the Air in Los Angeles

Although Los Angeles has the most polluted skies in the


nation, it is one of the few cities where air quality has
improved in recent decades

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Large Igneous Provinces

These vast fields of lava record powerful but geologically


brief pulses of magmatic activity. Their formation may have
triggered significant changes in the global environment

Evolutionarily Mobile Modules in


Proteins

Many proteins consist of a fairly small set of modular


elements. How these units spread and multiplied during
evolution is not altogether clear, but a pattern may be
emerging

Electrorheological Fluids

Some liquids solidify instantly when exposed to an electric


field. Such protean materials may give engineers quicker,
more adaptive machines

Water-Pollinated Plants

Once thought to be mere aberrations of nature, these


flowering aquatic species provide evidence for the
evolutionary convergence toward efficient pollination
strategies

Simulating Brain Damage

Adults with brain damage make some bizarre errors when


reading words. If a network of simulated neurons is trained to
read and then is damaged, it produces strikingly similar
behavior

Raising the Vasa

This Swedish man-of-war foundered on her maiden voyage


and slept for three centuries at the bottom of Stockholm
Harbor. Here is the story of her resurrection

The Death of Proof

Computers are transforming the way mathematicians


discover, prove and communicate ideas, but is there a place
for absolute certainty in this brave new world?

The Amateur Scientist

Making Fluids into Solids with Magnets

Sep 1993
Life, Death and the Immune System

By defining and defending the self, the immune system makes


life possible; malfunction causes illness and death. Study of
the system provides a unifying view of biology

How the Immune System Develops

Environmental and genetic signals cue cells as they


differentiate into the many lineages that recognize foreign
antigens and fight off invaders

How the Immune System Recognizes


Invaders

Cells of the immune system recombine gene fragments to


create the millions of receptors needed to identify and attack
the myriad pathogens encountered throughout life

How the Immune System Recognizes


the Body

The human immune system has developed several elegant


processes that allow it to repel foreign invaders and yet not
attack the body itself

Infectious Diseases and the Immune


System

When bacteria, viruses and other pathogens infect the body,


they hide in different places. Each component of the immune
system is most adept at rousting trespassers from one location

AIDS and the Immune System

The AIDS virus exploits the immune system to replicate


itself. New findings are showing how it wreaks havoc on the
body's defenses

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Autoimmune Disease

Misguided assaults on the self produce multiple sclerosis,


juvenile diabetes and other chronic illnesses. Promising
therapies are emerging

Allergy and the Immune System

In allergic individuals, parts of the immune system misdirect


their power at innocuous substances, producing sometimes
deadly symptoms

The Immune System as a Therapeutic


Agent

New technologies and insights into the molecular


underpinnings of the immune system provide the basis for
novel approaches to vaccines and other therapies

Will We Survive?

As host and pathogen evolve together, will the immune


system retain the upper hand?

Mathematical Recreations

A Shepherd Takes a Sheep Shot

Aug 1993
Eliminating Nuclear Warheads

More than 50,000 nuclear weapons may be decommissioned


during the next 10 years. Their disposal requires both
technical and political innovations

Faster than Light?

Experiments in quantum optics show that two distant events


can influence each other faster than any signal could have
traveled between them

T Cell Anergy

When cells of the immune system "see" antigens in the


absence of the right cosignals, they shut themselves down
instead of attacking. Future therapies might capitalize

A Universe of Color

Color photography continues to be an important astronomical


tool that reveals details of celestial objects not yet captured
by modern electronic detectors

Mastering Chaos

It is now possible to control some systems that behave


chaotically. Engineers can use chaos to stabilize lasers,
electronic circuits and even the hearts of animals

Diet and Primate Evolution

Many characteristics of modern primates, including our own


species, derive from an early ancestor's practice of taking
most of its food from the tropical canopy

The Great Radium Scandal

William J. A. Bailey grew rich from his radium-laced patent


medicine until it killed a leading socialite. The scandal helped
to usher in modern standards of radioisotope regulation

Trends in Communications

A technophile vice president and the information,


entertainment and communications industries have
discovered the source of next generation electronic products it's the network.

The Amateur Scientist

Circuits That Get Chaos in Sync

Jul 1993
Risk Analysis and Management

Inadequate approaches to handling risks may result in bad


policy. Fortunately, rational techniques for assessment now
exist

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Viral Quasispecies

The standard definition of a biological species does not apply


to viruses. A more expansive and dynamic view of viral
populations holds clues to understanding and defeating them

Australia's Polar Dinosaurs

Their excellent night vision and apparent warm blood raise a


question: Could they have survived icehouse conditions at the
end of the Cretaceous period?

Accurate Measurement of Time

Increasingly accurate clocks - now losing no more than a


second over millions of years - are leading to such advances
as refined tests of relativity and improved navigation systems.

Surgical Treatment of Cardiac


Arrhythmias

To save the life of a doomed patient, the author and his


colleagues developed a now standard surgical procedure for
correcting lethally fast heartbeats in many people susceptible
to them

Fuzzy Logic

The binary logic of modern computers often falls short when


describing the vagueness of the real world. Fuzzy logic offers
more graceful alternatives

Edwin Hubble and the Expanding


Universe

More than any other individual, he shaped astronomers'


present understanding of an expanding universe populated by
a multitude of galaxies

Sustaining the Amazon

Can scientists reconcile the inevitability of economic


development with the preservation of rain forests?

Mathematical Recreations

The Topological Dressmaker

Jun 1993
Underground Records of Changing
Climate

Boreholes drilled into continental rock can recover fossil


temperatures that reveal the climate of past eras. The results
require careful interpretation

The Most Distant Radio Galaxies

Astronomers have identified powerful radio emitting galaxies


that existed when the universe was only one tenth its present
age. These objects offer a glimpse at the early evolution of
giant galaxies

The Centrosome

By directing the assembly of a cell's skeleton, this organelle


controls division, motility and shape. The details of its
structure and function are just beginning to emerge

The Future of the Transistor

As it has grown smaller and cheaper, engineers have scoffed


at theoretical barriers to its progress - so far

Monogamy and the Prairie Vole

Studies of the prairie vole - a secretive, mouselike animal have revealed hormones that may be responsible for
monogamous behavior

Autism

Autistic individuals suffer from a biological defect. Although


they cannot be cured, much can be done to make life more
hospitable for them

The Great Well of China

More than 150 years ago the Chinese drilled one kilometer
into the earth to extract brine for making salt. The well was
the culmination of an 800-year-old technology

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Eugenics Revisited

Scientists are linking genes to a host of complex human


disorders and traits, but just how valid - and useful - are these
findings?

Mathematical Recreations

A Bundling Fool Beats the Wrap

May 1993
The Economics of Life and Death

Mortality data can be used to analyze economic performance.


Such information can illuminate critical aspects of the
economic organization of society

The Core-Mantle Boundary

This interactive zone may be the most dynamic part of the


planet, directly affecting the earth's rotation and magnetic
field.

How Cells Respond to Stress

During emergencies, cells produce stress proteins that repair


damage. Inquiry into how they work offers promise for
coping with infection, autoimmune disease and even cancer

Intelligent Gels

Soft aggregations of long-chain molecules can shrink or swell


in response to stimuli. They may form the basis of a new kind
of machine.

The Power of Maps

The authoritative appearance of modern maps belies their


inherent biases. To use maps intelligently, the viewer must
understand their subjective limitations

The Neurobiology of Fear

Researchers are beginning to tease apart the neurochemical


processes that give rise to different fears in monkeys. The
results may lead to new ways to treat anxiety in humans

P. A. M. Dirac and the Beauty of


Physics

He preferred the beautiful theory to the fact-buttressed ugly


one because, as he noted, facts change. He proved his point
by predicting the existence of antimatter.

Inconstant Cosmos

Space-based telescopes endowed with x-ray and gamma-ray


vision observe an ever restless, dynamic universe.

The Amateur Scientist

Mapping to Preserve a Watershed

Apr 1993

The Aging of the Human Species

Our species has modified the evolutionary forces that have


always limited life expectancy. Policymakers must
consequently prepare to meet the needs of a population that
will soon be much older

Cavity Quantum Electrodynamics

Atoms and photons in small cavities behave completely


unlike those in free space. Their quirks illustrate some of the
principles of quantum physics and make possible the
development of new sensors

Listening with Two Ears

Studies of barn owls offer insight into just how the brain
combines acoustic signals from two sides of the head into a
single spatial perception

Catalysis on Surfaces

Scientists can now observe how solids interact with individual


molecules to speed reactions. Information about these
catalysts is being used to improve everything from materials

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synthesis to pollution control


The Reproductive Behavior of the
Stickleback

To reproduce, this tiny fish engages in behaviors not


commonly associated with such animals, including luring
intruders away and cannibalizing another's eggs

The Evolution of Virulence

Human behavior appears to influence whether pathogens


evolve into benign or harmful forms. Health policy should
therefore include evolutionary considerations

Modern Humans in the Levant

Modern Homo sapiens preceded Neanderthals on Mount


Carmel and followed a similar pattern of life for 60,000 years.
Biology thus cannot explain the cultural revolution that then
ensued

Trends in Materials

Rehabilitating the nation's aging infrastructure may depend


on how well industry, government and academia tweak the
properties of materials, from lowly concrete to aerospace
composites

Mathematical Recreations

The Rise and Fall of the Lunar M-pire

Mar 1993
Why America's Bridges are Crumbling

Inadequate maintenance has piled up a repair bill that will


take decades to pay off. Indeed, the scope of the problem is
only now becoming clear

Black Holes and the Centrifugal Force


Paradox

An object orbiting close to a black hole feels a centrifugal


force pushing inward rather than outward. This paradoxical
effect has important implications for astrophysics

Teaching the Immune System to Fight


Cancer

Certain molecules on tumors can serve as targets for attack


by cells of the immune system. These tumor-rejection
antigens may provide a basis for precisely targeted anticancer
therapy

Flat Panel Displays

Recent advances in microelectronics and liquid crystals make


possible video screens that can be hung on a wall or worn on
a wrist.

How Parasitic Wasps Find Their Hosts

Besides recognizing odors from their caterpillar hosts, wasps


also learn to identify compounds released by the plant on
which the caterpillars feed

Ice Age Lamps

The invention of fat-burning lamps toward the end of the Ice


Age helped to transform European culture. It coincided with
several other major technological advances

Flooded Forests of the Amazon

Parts of the vast rain forest are as much aquatic as terrestrial


ecosystems. Unique adaptations allow creatures to thrive in
these inundated woods

Trends in Genetics DNA'S New Twists

The known rules of genetics are only the beginning. The


newly discovered abilities of a familiar molecule are
influencing theories about evolution and the inheritance of
disease.

The Amateur Scientist

Flight-Testing Fruit Flies

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Feb 1993
Environmental Change and Violent
Conflict

Growing scarcities of renewable resources can contribute to


social instability and civil strife

Resistance in High-Temperature
Superconductors

Researchers are beginning to see how the motion of magnetic


vortices in these materials can interfere with the flow of
current

Zinc Fingers

They play a key part in regulating the activity of genes in


many species, from yeast to humans. Fewer than 10 years ago
no one knew they existed

How Should Chemists Think?

Chemists can create natural molecules by unnatural means.


Or they can make beautiful structures never seen before.
Which should be their grail?

A Technology of Kinetic Art

Delicate interplay of weights and balances choreographs the


author's sculptures so that the gentlest gusts of air set their
parts in motion

Breaching the Blood-Brain Barrier

Development of a therapy for meningitis has revealed how


bacteria penetrate the blood-brain barrier. This knowledge
may help physicians treat other disorders of the brain

Redeeming Charles Babbage's


Mechanical Computer

A successful effort to build a working, three-ton Babbage


calculating engine suggests that history has misjudged the
pioneer of automatic computing

Trends in Russian Science

Researchers in the Russian Federation are in desperate straits.


Plummeting budgets and pitiful salaries are driving many to
leave the country. Those who stay are being forced to
become merchant adventurers.

Mathematical Recreations

A Partly True Story

Jan 1993
Coral Bleaching

Environmental stresses can cause irreparable harm to coral


reefs. Unusually high seawater temperatures may be a
principal culprit

How the Milky Way Formed

Its halo and disk suggest that the collapse of a gas cloud,
stellar explosions and the capture of galactic fragments may
have all played a role

Carbohydrates in Cell Recognition

Telltale surface sugars enable cells to identify and interact


with one another. New drugs aimed at those carbohydrates
could stop infection and inflammation

The Earliest History of the Earth

Radioactive dating techniques have illuminated vast stretches


of geologic history, bringing the most ancient eras of the
earth's evolution into view

Madagascar's Lemurs

These primates can tell us a great deal about our own


evolutionary past. But many species are already extinct, and
the habitats of those that remain are shrinking fast

Quantum Dots

Nanotechnologists can now confine electrons to pointlike


structures. Such "designer atoms" may lead to new electronic

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and optical devices


The Mind and Donald O. Hebb

By rooting behavior in ideas, and ideas in the brain, Hebb laid


the groundwork for modern neuroscience. His theory
prefigured computer models of neural networks

Adapting To Complexity

From a primeval sea of organic molecules arose plants,


animals, global ecosystems, intelligent beings, international
organizations. What drives the natural world toward
complexity?

The Amateur Scientist

Biodiversity in the Backyard

Compiled by Dave Lo, article summaries Scientific American

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