Ateneo de Zamboanga University

College of Nursing
RELATED LEARNING EXPERIENCE
DRUG STUDY FORMAT
DRUG

BRAND NAME:
Vibramycin
GENERIC
NAME:
Doxycycline
DOSAGE AND
FREQUENCY:
200 mg STAT, /
100 mg B.I.D.
for 3 days
ROUTE:
Per Orem

INDICATIONS

ACTIONS

Doxycycline is
sometimes effective for
trivial infections of the
upper respiratory tract
or of the (genito-)urinary
tract but it does not
represent the drug of
choice.

May
exert
bacteriostatic
effect
by
binding to the
30S
and
possibly 50S
ribosomal
units
of
microorganis
ms
and
inhibiting the
protein
synthesis.
May also alter
the
cytoplasmic
membrane of
susceptible
microorganis
ms.

It is particularly well
suited for atypical
pneumonia (as long as
a legionella infection
can be excluded), for
disease
following Chlamydia
trachomatis (nongonorrhoeal urethritis,
acute urethral
syndrome, venereal

SIDE EFFECTS/
ADVERSE
REACTIONS
Spectacular
Senses: Interfe
rence with color
vision.

NURSING
RESPONSIBILITIES

GI: Anorexia,
nausea,
vomiting,
diarrhea,
enterocolitis;
esophageal
irritation
(oral
capsule
and
tablet).

Skin: Rashes,
photosensitivity
reaction.

Others: Throm

Obtain specimen
for culture and
sensitivity.
Check
for
expiration
date
because outdated
tetracycline may
cause reversible
nephrotoxicity.
Monitor for signs
and symptoms of
superinfection in
patients with long
term and high
dose use of this
drug.
Check
the
patients tongue
for
fungal
infection. Stress

CLIENT TEACHING

Instruct patient to
take the full course
prescribed. Do not
take with antacids.
Tablets and oral
suspension can be
taken with or without
food.
Instruct patient to
take capsule or
tablet forms with a
full glass (240 mL)
of water to ensure
passage into
stomach and
prevent esophageal
ulceration. Avoid
taking capsule or
tablet within 1 h of
lying down or

lymphogranuloma, etc.),
for brucellosis (in
combination with e.g.
rifampicine), for
rickettsial diseases
(spotted fever, Q fever),
for cholera and for
anthrax. Doxycycline
can be applied in stage I
of Lyme disease.
Doxycycline is
considered an
alternative drug
for syphilis when there
is e.g. a hypersensitivity
to penicillin. It is
recommended as a
follow-up treatment to a
single dose of
ceftriaxone for the
treatment of possible
chlamydia infections in
context
with gonorrhoea. It is
used in combination
with other antibiotics
foracute inflammatory
pelvic disease caused
by mixed infections. It
can also be used for the
prophylaxis of traveler's

bophlebitis (IV
use),
superinfections.

for oral hygiene.

Report severe or
watery diarrhea,
severe nausea or
vomiting, rash or
itching,
mouth
sores,
vaginal
sores.

Report sudden
onset of painful
or difficult
swallowing
promptly to
physician.
Doxycycline
(capsule and
tablet forms) is
associated with a
comparatively
high incidence of
esophagitis,
especially in
patients >40 y.

retiring.
Advice patient
to avoid exposure to
direct sunlight and
ultraviolet light
during and for 4 or 5
d after therapy is
terminated to reduce
risk of phototoxic
reaction. Phototoxic
reaction appears like
exaggerated
sunburn.
Sunscreens provide
little protection.
Advice mothers, do
not breast feed while
taking this drug.
Advice patient that
she/he
may
experience
these
side
effects:
discomfort, diarrhea;
fatigue,
headache
(medication
may
help);
additional
infections in the
mouth or vagina
(consult with health
care provider for

diarrhea. Doxycycline
can also be considered
for the prevention or
treatment of
multiresistant malaria
(e.g. in Thailand).

PREPARED BY: Haifa U. Alibasa, SN, ADZU

treatment).

CHECKED BY:

Advice patient to
report severe or
watery
diarrhea,
severe nausea or
vomiting, rash or
itching, mouth sores,
vaginal sores.

Advice patient to
report sudden onset
of painful or difficult
swallowing promptly
to physician.
Doxycycline
(capsule and tablet
forms) is associated
with a comparatively
high incidence of
esophagitis,
especially in patients
>40 y.

Mr. Edwin Abu, RN, MN

_________________________
Clinical Instructor