Course Outline for 125:355, Physiological Systems for Biomedical Engineers

Fall, 2015, Mon, Thursday, 5:00 to 6:20 PM, BME 102 (Auditorium)
Prof. George Shoane, shoane@rci.rutgers.edu, 848-445-6583, Room 306, Biomedical Engin.
Bldg. Busch Campus. Office Hour: Fridays 4-5 PM.
Textbook: Selected-Chapters Edition of Vanderss Human Physiology, The Mechanisms of
Body Function, Widmaier, Raff, and Strang, McGraw-Hill, 13th Edition, 2014.
Lecture Chapter
1

Topics
Chemical Composition of the Body
Atoms, molecules, ions, free radicals, polar molecules

Solutions, classes of organic molecules carbohydrate, lipids, proteins, nucleic acids

3

3
4

Cell Structure and Protein Function

A.

Cell Structure

B.

Proteins Transcription from DNA to RNA, and translation from RNA to protein

C.

Protein Binding Sites

D. Enzymes and Chemical Energy

5

E.
4

Metabolic Pathways Glycolysis, Krebs cycle, oxidative phosphorylation

Movement of Molecules Across Cell Membranes

Diffusion, mediated transport

Osmosis, endocytosis, exocytosis, epithelial transport, glands

5

Control of Cells by Chemical Messengers

Intracellular receptors, plasma membrane receptors: ion channel, tyrosine kinase, JAK
kinase, G protein

Calcium as 2nd messenger, eicosanoids, transcription factors

6

10
11

Neuronal Signaling and the Structure of the Nervous System

A.

Neural Tissue

B.

Membrane Potentials

C.

Synapses Neurotransmitters and neuromodulators

D. Structure of the Nervous System

9

Muscle

12

A.

Skeletal Muscle

13

B. Smooth Muscle

14

Midterm Review

15

MIDTERM

12

Cardiovascular Physiology

16

A.

Overall Design of the Cardiovascular System

B.

The Heart

17-18

C. The Vascular System

18-20

D. Integration of Cardiovascular Function: Regulation of Systemic Arterial Pressure

21

E.
11

Cardiovascular Pattern in Health and Disease

The Endocrine System

22

A.

General Characteristics of Hormones and Hormonal Control Systems

B-C. The Hypothalamus and Pituitary Gland; The Thyroid Gland

23

D.

24

E-F. Endocrine Control of Growth; Endocrine Control of Ca2+ Homeostasis

13

The Endocrine Response to Stress

Respiratory Physiology

25

Organization of the respiratory system, ventilation and lung mechanics, how stable
balance is achieved between breaths, exchange of gases in alveoli and tissues

26

Transport of oxygen, carbon dioxide, and hydrogen in the blood

27

Control of respiration, hypoxia, nonrespiratory functions of the lungs

Grading:

Percent

Attendance

Warning: Signing for an absent student will mean a total of

0% for both students, plus Administrative disciplinary action.

Practice Quiz

Non-graded. Collected at end of each lecture.

Homework (Connect)
LearnSmart/Smartbook
Midterm
Final

15
38
_38_
100

Web Access: sakai.rutgers.edu,; Log-in; Select Physiol Systems F15; Click Modules.
** Students must also sign up for access to: Connect LearnSmart/SmartBook - adaptive learning
homework. [connectstudentsuccess.com]; select: Registering for Connect; In Connect, use address
http://connect.mheducation.com/class/g-shoane-fall-2015
** Because of continued inappropriate usage via the wireless connection, laptops and other electronic
devices will not be permitted during lectures. Download lecture notes from Sakai before class.
** There will be a 20% deduction for any Make-Up Exam, except for a real medical emergency (this
does not include just having a visit at the clinic).
2