Lynn G. Dunikowski W.

Wayne Weston

A Library for Family Physicians:

Recommended List of Books and Journals
Ms. Dunikowski is librarian of the
Canadian Library of Family
Medicine, the library service of The
College of Family Physicians of
Canada, and editor of FAMLI
(Family Medicine Literature
Index). Dr. Weston is an associate
professor and chairman of the
Library Committee, Department of
Family Medicine at the University
of Western Ontario. Reprint
requests to: Canadian Library of
Family Medicine, Sciences Library,
Natural Sciences Centre, University
of Western Ontario, London,
N6A 5B7.
rrHIS LIST updates the list which
Xappeared in July 1982.1 It recommends a basic collection for family
physicians in a teaching centre or
small hospital library. Family physicians wanting to add books to their
personal or practice libraries may also
find it useful.
This revision was compiled by the
Canadian Library of Family Medicine,
in consultation with the Library Committee of the Department of Family
Medicine, University of Western Ontario. Additional input was obtained
from the results of a questionnaire on
the updating of the 1982 list. This
questionnaire was mailed to 100 health
professionals (family physicians, specialists, medical librarians and others),
60% of whom responded. All recommendations were given serious consideration when selection decisions
were being made.
Books were selected on the basis of
their quality, currency, and relevance
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

to the practice of family medicine. The

selections reflect a view of family
medicine as a unique discipline rather
than an amalgam of all the specialties.
The list is not meant to be all-inclusive
of every subspecialty area, but rather
to reflect the nature and frequency of
problems encountered by the family
physician. The list covers a broader
range of areas than many other booklists-for example, there are categories for education, doctor-patient relationship, and ethics. Wherever
possible, the books selected were written by or for family physicians. The
books are categorized by the subject
headings listed following the introduction.
The list recommends a total purchase of 138 books, nine reference
volumes, and six journal subscriptions
tor one year. The approximate total
cost of this collection is $5,000, based
on prices in mid-1984. By comparison, the total cost of the 1982 list was
$4,000. The list provides choices between books or journals which were
felt to be of comparable quality, or in
some cases between books which
cover the core of a subject and those
which provide in-depth treatment. The
list may thus be used as a guide to select those materials most useful in a
particular library or centre, depending
on budget restrictions and emphasis on
particular aspects of medical practice.
For those physicians with a limited
budget who want a small collection of
books for ready reference in the office,
a minimum collection has been identified (see Fig. 1). As in the main list,
choices are provided in many cate-

gories. The cost of this ready-reference collection of 22 books ranges

from approximately $950 to approximately $1,490, depending on the
books selected.
Following the practice of the 1982
list, there is an appendix which lists a
selection of books on medicine in literature. The cost of these books has not
been included in the total cost of the
recommended collection, and these
books have not been included in the
author/abbreviated title index.
When building a collection for a
medical centre or hospital library, it
may be helpful to review other available medical library booklists. 2-7

References
1. Fitzgerald D, Corbett D, Weston WW.
Basic library listforfamily medical centres
and small hospitals, 1982. Can Fam Physician 1982; 28:1305-12.
2. Allyn R. A library for internists IV: recommended by the American College of
Physicians. Ann Int Med 1982; 96:385401.
3. Brandon AN, Hill DR: Selected list of
books and journals for the small medical library. Bull Med Libr Assoc 1983; 71:14775.
4. Denham JW: Family practice library.
In: Taylor RB, (ed). Family medicine:
principles and practice, 2nd ed. New
York: Springer, 1983: 1953-9.
5. Hamilton GC, Epstein FB, Jagger J, et
al: A new library for emergency medicine.
Ann Emerg Med 1983; 12:687-96.
6. Ontario Medical Association. Suggested
list of medical books and journals 1984. (in
prep.) Available from the Library, Ontario
Medical Association, 240 St. George St.,
Toronto, Ontario. MSR 2P4
7. Wender RW, Parrish JW, Holman KG,
Thompson CM, Callard JC. Primary care
physician's book list. Postgrad Med 1982;
71:74-7,81-3.
2159

IN THE TREATMENT OF HYPERTENSION

Aging and Geriatrics

Allergy and Immunology
Anatomy
Anesthesiology
Arthritis and Rheumatism

Sociology
Sports Medicine
Surgery
Urology

Biography and History

AGING AND GERIATRICS

ADULT DOSAGE: Hypertension: Starting dosage is one tablet

twice daily after meals. Dosage can be subsequently increased
or decreased according to patient's need. If two or more tablets
per day are needed, they should be given in divided doses.
Edema: Starting dosage is one tablet twice daily after meals.
When dry weight is reached, the patient may be maintained on
one tablet daily. Maximum dosage four tablets daily.
INDICATIONS: Mild to moderate hypertension in patients who
have developed hypokalaemia and in patients in whom potassium
depletion is considered especially dangerous (e.g. digitalized
patients). Medical opinion is not unanimous regarding the
incidence and/or clinical significance of hypokalaemia occurring
among hypertensive patients treated with thiazide-like diuretics
alone, and concerning the use of potassium-sparing combinations
as routine therapy in hypertension.
Edema of congestive heart failure, cirrhosis, nephrotic syndrome,
steroid-induced edema and idiopathic edema. 'Dyazide' is useful
in edematous patients whose response to other diuretics is
inadequate.
CONTRAINDICATIONS: Progressive renal dysfunction (including
increasing oliguria and azotemia) or increasing hepatic dysfunction. Hypersensitivity. Elevated serum potassium. Nursing mothers.
WARNINGS: Do not use potassium supplementation or other
potassium conserving agents with 'Dyazide since hyperkalaemia
may result. Hyperkalaemia (5.4 mEq/L) has been reported
ranging in incidence from 4% in patients less than 60 years of
age to 12% in patients 60 and older, with an overall incidence of
less than 8%. Rare cases have been associated with cardiac
irregularities. Make periodic serum potassium determinations,
particularly in the elderly, in diabetics, and in suspected or
confirmed renal insufficiency. If hyperkalaemia develops, withdraw
'Dyazide' and substitute a thiazide alone.
Hypokalaemia is less common than with thiazides alone, but if it
occurs it may precipitate digitalis intoxication.
PRECAUTIONS: Check laboratory data (e.g. BUN, serum electrolytes) and ECG's periodically, especially in the elderly, in
diabetics, in renal insufficiency, and in those who have developed
hyperkalaemia on 'Dyazide' previously. Electrolyte imbalance
may occur, especially where salt-restricted diets or prolonged
high-dose therapy is used. Observe acutely ill cirrhotic patients
for early signs of impending coma. Reversible nitrogen retention
may be seen. Observe patients regularly for blood dyscrasias,
liver damage or other idiosyncratic reactions; perform appropriate
laboratory studies as required. Sensitivity reactions may occur,
particularly in patients with history of allergy or bronchial asthma.
Periodic blood studies are recommended in cirrhotics with
splenomegaly. Adjust dosage of other antihypertensive agents
given concomitantly. Antihypertensive effects of 'Dyazide' may
be enhanced in the post-sympathectomy patient. Hyperglycemia
and glycosuria may occur. Insulin requirement may be altered in
diabetics.
Hyperuricemia and gout may occur. Thiazides have been reported
to exacerbate or activate systemic lupus erythematosus.
Pathological changes in the parathyroid glands have been reported
with prolonged thiazide therapy. Triamterene may cause a decreasing alkali reserve, with the possibility of metabolic acidosis. Serum
transaminase elevabons sometimes occur with 'Dyazide' Thiazides
can decrease arterial responsiveness to norepinephrine and
increase tubocurarine's paralyzing effect; exercice caution in
patients undergoing surgery. Thiazides cross the placental barrier
and appear in breast milk; this may result in fetal or neonatal
hyperbilirubinemia, thrombocytopenia, altered carbohydrate
metabolism and possible other adverse reactions that have
occurred in the adult. Use in pregnancy only when deemed
necessary for the patient's welfare.
ADVERSE REACTIONS: The following adverse reactions have
been associated with the use of thiazide diuretics or triamterene:
Gastrointestinal: dry mouth, anorexia, gastric irritation, nausea,
vomiting, diarrhea, constipation, jaundice (intra-hepatic cholestatic) pancreatitis, sialadentis. Nausea can usually be prevented
by giving the drug after meals. It should be noted that symptoms
of nausea and vomiting can also be indicative of electrolyte
imbalance (See Precautions).
Central nervous system: dizziness, vertigo, paresthesias,
headache, xanthopsia.
Dermatologic-Hypersensitivity: fever, purpura, anaphylaxis,
photosensitivity, rash, urticaria, necrotizing angiitis.
Hematologic: leukopenia, thrombocytopenia, agranulocytosis,
aplastic anemia.
Cardiovascular: orthostatic hypotension may occur and may be
potentiated by alcohol, barbiturates, or narcotics.
Electrolyte imbalance (See Precautions).
Miscellaneous: hyperglycemia, glycosuria, hyperuricemia, muscle
spasm, weakness, restlessness, transient blurred vision.
SUPPLY: Scored peach-coloured compressed tablets monogrammed SKF E93 in bottles of 100, 1,000 and 2,500. DIN 181528.
PAAB Full prescribing information available Upon request.

LIST OF SUBJECT
HEADINGS USED

Child Care
Communicable and Infectious
Diseases
Dentistry
Dermatology
Diagnosis and Clinical Methods
Doctor-Patient Relationship and
Interviewing
Education
Emergency Medicine
Ethics
Family, Marriage and Sexuality
Family Medicine

Genetics
Grief, Death and Dying, and
Palliation
Growth and Development
Internal Medicine

Laboratory Medicine

Medicolegal Issues
Nursing
Nutrition

Writing
1. Adams G. Essentials of geriatric medicine.
2nd ed. New York: Oxford Univ. Press, 1981.

$13.95.
OR
2. Brocklehurst JC, Hanley T. Geriatric medicine for students. 2nd ed. Edinburgh: Churchill
Livingstone, 1981. $16.90.
OR
3. Cape RD, Coe RM, Rossman I, eds. Fundamentals of geriatric medicine. New York:
Raven Press, 1983. $22.75.
4. Reichel W, ed. Clinical aspects of aging.
2nd ed. Baltimore: Williams & Wilkins, 1983.
$62.45.
OR
5. Rossman I, ed. Clinical geriatrics. 2nd ed.
Philadelphia: Lippincott, 1979. $68.75.
OR
6. Steinberg FU, ed. Cowdry's The care of the
geriatric patient. 6th ed. St. Louis: Mosby,
1982. $70.75.
7. The College of Family Physicians of Canada. To comfort always: caring for the older patient-a challenge for family physicians.
Toronto: CFPC, 1980. $2.50.
8. Herr JJ, Weakland JH. Counseling elders
and their families. New York: Springer, 1979.

$22.50.

ALLERGY AND IMMUNOLOGY

9. Patterson R, ed. Allergic diseases: diagnosis
and management. 2nd ed. Philadelphia: Lippincott, 1980. $68.75.

ANATOMY
10. Ellis H. Clinical anatomy. 7th ed. Oxford:
Blackwell Scientific, 1983. $33.50.
OR
11. Snell RS. Clinical anatomy for medical students. 2nd ed. Boston: Little, Brown, 1981.

$49.50.

Obstetrics and Gynecology

Occupational and Industrial
Medicine

Oncology
Ophthalmology
Orthopedics
Otorhinolaryngology
Pathology
Patient Education
Pharmacology and Therapeutics
Physical Medicine and
Rehabilitation
Physiology
Practice Management and Records
Preventive Medicine
Psychological Problems

The books by Ellis and Snell are clinically

oriented texts covering the core of anatomical
knowledge for physicians. For those wanting
more extensive coverage the following have
been selected:
12. Anderson JE. Grant's atlas of anatomy. 8th
ed. Baltimore: Williams & Wilkins, 1983.

$49.40.
13. Basmajian JV. Grant's method of anatomy.
10th ed. Baltimore: Williams & Wilkins, 1980.
$41.60.
OR
14. Warwick R, Williams PL. Gray's anatomy.
36th ed. Edinburgh: Churchill Livingstone,
1980. $150.

ANESTHESIOLOGY
15. Dripps RD, et al. Introduction to anesthesia: the principles of safe practice. 6th ed. Philadelphia: Saunders, 1982. $36.90.
16. Moore DC. Regional block: a handbook for
use in the clinical practice of medicine and surgery. 4th ed. Springfield, Ill: C. C. Thomas,
1978. $29.75.

Radiology
Research

ARTHRITIS AND RHEUMATISM

Social Work

17. Rodnan GP, Schumacher HR, eds. Primer

on the rheumatic diseases. 8th ed. Atlanta: Ar-

2160

DYAZIDE
(25rmg hydrochlorothiazide, 50 mg triamterene)

SIMPLIFIES CONTROL

LCCPP

Smith Kline & French Canada Ltd., 1084

DZ:M:184CA

POTASSIUM-SPARING
DYAZIDE MAKES SENSE.

Dyazide
(5 no vvdrocvlororviazide. 50 no triamlerenel

a 5mI4.m

co_ian

SMITH KLINE SFRENCH CANADA LTD.

M,ss.ss~eaug Oni LSN 2V7

thritis Foundation, 1983. (available from Arthritis Society, 420-920 Yonge St., Toronto,
Ontario, M4W 3J7.) $5.

BIOGRAPHY AND HISTORY

18. Ackerknecht EA. A short history of medicine. rev. ed. Baltimore: Johns Hopkins, 1982.
$10.50.
19. Berger J, Mohr J. A fortunate man. London: Writers & Readers, 1976. $5.25.
20. McKeown T. The role of medicinedream, mirage or nemesis? 2nd ed. Oxford:
Basil Blackwell, 1979. $16.95.
21. Woods D. Strength in study. Toronto: The

College of Family Physicians of Canada, 1979.

$15.

CHILD CARE
22. Behrman RE, Vaughan VC 3d, eds. Nelson
textbook of pediatrics. 12th ed. Philadelphia:
Saunders, 1983. $104.
OR
23. Rudolph AM, Hoffman J, eds. Pediatrics.
17th ed. New York: Appleton-Century-Crofts,
1982. $99.50.
24. Green M, Haggerty RJ. Ambulatory pediatrics three: personal health care of children in
the office. Philadelphia: Saunders, 1984.

$60.75.

TABLE 1
A Ready Reference Collection for Family Physicians. (The number
after each title is the number of the book in the main list.)
AGING AND GERIATRICS: Essentials of geriatric medicine (1), OR
Geriatric medicine for students (2), OR Fundamentals of geriatric
medicine (3).
CHILD CARE: Nelson textbook of pediatrics (22), OR Pediatrics (23);
AND Ambulatory pediatrics three (24).
COMMUNICABLE AND INFECTIOUS DISEASES: Control of
communicable diseases in man (30); AND A guide to immunization for
Canadians (31).
DERMATOLOGY: A manual of dermatology (34), OR Manual of skin
diseases (35), OR Dermatology: diagnosis and treatment of cutaneous
disorders (36).
EMERGENCY MEDICINE: Flint's emergency treatment and
management (59), OR Emergency medicine: concepts and clinical
practice (60), OR Textbook of emergency medicine (61); AND Handbook
of poisoning (62), OR Clinical management of poisoning and drug
overdose (63).
FAMILY MEDICINE: Textbook of family practice (78), OR Family
medicine: principles and practice (79).
INTERNAL MEDICINE: The principles and practice of medicine (107),
OR Harrison's principles of internal medicine (108), OR Oxford textbook
of medicine (109), OR Cecil textbook of medicine (110).
LABORATORY MEDICINE: Biochemical values in clinical medicine
(1 1 1), OR Interpretation of diagnostic tests (1 12).
NUTRITION: Diet manual (125).
OBSTETRICS AND GYNECOLOGY: Office gynecology (126), OR
Women's problems in general practice (127); AND Williams obstetrics

(130).
OPHTHALMOLOGY: Ophthalmology: principles and concepts (135), OR
General ophthalmology (136).
ORTHOPEDICS: Outline of fractures (138), OR DePalma's The
management of fractures and dislocations (139); AND Outline of
orthopaedics (140), OR Textbook of orthopaedic medicine (141), OR
Orthopaedics in primary care (142), OR Textbook of disorders and
injuries of the musculoskeletal system (143).
PHARMACOLOGY AND THERAPEUTICS: AMA drug evaluations
(151), OR Goodman and Gilman's The pharmacological basis of
therapeutics (152).
PREVENTIVE MEDICINE: Periodic health examination (173).
PSYCHOLOGICAL PROBLEMS: Modern synopsis of comprehensive
textbook of psychiatry (177), OR Modern clinical psychiatry (178).
SURGERY: Davis-Christopher textbook of surgery (196), OR Principles
of surgery (197); AND Ambulatory surgery and the basics of emergency
suroical care (198).
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

Ecostatin
(ECONAZOLE NITRATE)
TOPICAL CREAM, 1%
THERAPEUTIC CLASSIFICATION
Antifungal Agent
ACTIONS: Econazole nitrate exhibits antifungal
activity against a wide variety of fungi, including
dermatophytes, pathogenic yeasts, and moulds.
Susceptible pathogenic organisms include
Candida albicans and other Candida species,
Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and
Malassezia furfur. It appears to act by altering
the internal structure or cell membrane permeability of the fungus.
INDICATIONS: ECOSTATIN (econazole nitrate)
Topical Cream is indicated for the treatment of
infections caused by susceptible dermatophyte
and candida species including tinea pedis, tinea
cruris, tinea corporis, tinea versicolor and
cutaneous candidiasis. It is not indicated for
moderate or severe paronychia or onychomysosis.
CONTRAINDICATIONS: Hypersensitivity to
econazole nitrate or any of the cream's
components.
Not for ophthalmic use.
PRECAUTION: If marked irritation or sensitization should occur during topical use, discontinue
ECOSTATIN (econazole nitrate) therapy.
ADVERSE REACTIONS: ECOSTATIN (econazole
nitrate) Topical Cream is usually well tolerated.
Adverse effects are limited to occasional local
skin irritation manifested by erythema, pruritus.
and burning or stinging sensation; cessation of
therapy is rarely warranted.
SYMPTOMS AND TREATMENT OF OVERDOSAGE: None known.
DOSAGE AND ADMINISTRATION: ECOSTATIN
(econazole nitrate) Topical Cream should be
applied twice daily, in the morning and evening.
The cream should be massaged gently into the
affected and surrounding skin areas.
Clinical improvement usually occurs promptly;
however, complete disappearance of the
symptoms of the disease may require prolonged
treatment. Candida infections should be treated
for at least two weeks and dermatophyte infections for one month to reduce the risk of
recurrence. If no improvement has occurred after
one month of treatment with ECOSTATIN Topical Cream, the diagnosis should be reassessed.
AVAILABILITY: ECOSTATIN (econazole nitrate)
Topical Cream provides 1.0% econazole nitrate
formulated in a water-soluble cream base containing pegoxol-7-stearate, peglicol-5-oleate,
mineral oil, butylated hydroxyanisole, benzoic
acid, perfume, and purified water.
ECOSTATIN Topical Cream is available in 15 and
30 g tubes.
STORAGE: Store at room temperature

(1 5-25C).

Product Monograph available to physicians

on

request.

SQUIBB CANADA INC.

2365 COTE-DE-LIESSE
MONTREAL, QUEBEC H4N 2M7

2163

25. Hart CR. Child care in general practice.

2nd ed. Edinburgh: Churchill Livingstone,
1982. $55.
26. Illingworth RS. Common symptoms of disease in children. 7th ed. Oxford: Blackwell Scientific, 1982. $26.25.
27. Kempe CH, Silver HK, O'Brien D. Current
pediatric diagnosis and treatment. 8th ed. Los
Altos, Calif: Lange Medical, 1984. $35. 10.
28. Klaus MH, Fanaroff AA. Care of the high
risk neonate. 2nd ed. Philadelphia: Saunders,
1979. $34.35.

COMMUNICABLE AND
INFECTIOUS DISEASES
29. American Academy of Pediatrics. Report of
the Committee on Infectious Diseases. 19th ed.
Evanston, Ill: AAP, 1982. $15 (U.S.)
30. Benenson AS, ed. Control of communicable diseases in man. 13th ed. Washington, DC:
American Public Health Association, 1981.

$7.50. (U.S.)
31. National Advisory Committee on Immunization. A guide to immunization for Canadians.
2nd ed. Ottawa: Health and Welfare Canada,
1984 (in prep). (available from Director,
Bureau of Epidemiology, Laboratory Centre for
Disease Control, Tunney's Pasture, Ottawa.)
Free.
32. Wehrle PF, Top FH, eds. Communicable
and infectious diseases. 9th ed. St. Louis:
Mosby, 1981. $84.50.

DENTISTRY
33. Bhaskar SN. Synopsis of oral pathology.
6th ed. St. Louis: Mosby, 1981. $46.

DERMATOLOGY
34. Pillsbury DM, Heaton CL. A manual of dermatology. 2nd ed. Philadelphia: Saunders,
1980. $36.30.
OR
35. Sauer GC. Manual of skin diseases. 5th ed.
Philadelphia: Lippincott, 1984 (in prep).
$54.50.
OR
36. Stewart WD, Danto JL, et al. Dermatology:
diagnosis and treatment of cutaneous disorders.
4th ed. St. Louis: Mosby, 1978. $56.50.
37. Domonkos AN. Andrew's diseases of the
skin: clinical dermatology. 7th ed. Philadelphia:
Saunders, 1982. $97.70.

DIAGNOSIS AND
CLINICAL METHODS
38. Blacklow RS. MacBryde's signs and symptoms. 6th ed. Philadelphia: Lippincott, 1983.

$54.
OR
39. DeGowin EL, DeGowin RL. Bedside diagnostic examination. 4th ed. New York: Macmillan, 1981. $34.95.
OR
40. Judge RD, Zuidema GD. Clinical diagnosis:
a physiologic approach. 4th ed. Boston: Little,
Brown, 1982. $39.50.
41. Bursztajn H, Feinbloom RI, et al. Medical
choices, medical chances: how patients, families
and physicians can cope with uncertainty. New
York: Delacorte Press/Seymour Lawrence,
1981. $14.50.
42. Hodgkin K. Towards earlier diagnosis in primary care. 4th ed. Edinburgh: Churchill Livingstone, 1978. $30.65.
43. Wright HJ, MacAdam DB. Clinical thinking
and practice: diagnosis and decision in patient
care. 2nd ed. Edinburgh: Churchill Livingstone,
1979. $18.75.
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

DOCTOR-PATIENT
RELATIONSHIP
AND INTERVIEWING
44. Bernstein L, Bernstein RS. Interviewing: a
guide for health professionals. 3rd ed. New
York: Appleton-Century-Crofts, 1980. $16.95.
OR
45. Enelow AJ, Swisher SN. Interviewing and
patient care. 2nd ed. New York: Oxford Univ.
Press, 1979. $12.75.
46. Freeling P, Harris CM. The doctor-patient
relationship. 3rd ed. Edinburgh: Churchill
Livingstone, 1983. $15.75.
OR
47. Pendleton D, Hasler J, eds. Doctor-patient
communication. London: Academic Press,
1983. $38.
48. Balint M. The doctor, his patient and the illness. 2nd ed. New York: International Universities Press, 1964. $38.50.
49. Bird BR. Talking with patients. 2nd ed.
New York: Harper & Row, 1973. $22.
50. Byrne PS, Long BE. Doctors talking to patients: a study of the verbal behavior of general
practitioners consulting in their surgeries. London: HMSO, 1976. (reprint edition available
from the Publications Sales Office, Royal College of General Practitioners, 8 Queen St., Edinburgh EH2 IJE. 10.50.)

EDUCATION
51. Cormack J, Marinker M, Morrell D, eds.
Teaching general practice. Brentford, Middlesex: Kluwer, 1981. $55.
OR
52. Knopke HJ, Diekelmann NL, eds. Approaches to teaching primary health care. St.
Louis: Mosby, 1981. $31.50.
53. Bland CJ. Faculty development through
workshops. Springfield, Ill: C. C. Thomas,
1980. $19.75.
54. The College of Family Physicians of Canada. Canadian family medicine: educational objectives for certification in family medicine. 2nd
ed. Toronto: CFPC, 1981. $10.
55. Fabb WE, Heffernan MW, Phillips WA, et
al. Focus on learning in family practice. Melbourne: Royal Australian College of General
Practitioners, 1976. (also available from STFM,
1740 W. 92nd St., Kansas City, Mo. 64114.

$15 (U.S.).
56. Fabb WE, Marshall JR, eds. The nature of
general family practice. Lancaster: MTP Press,
1983. $40.
57. Royal College of General Practitioners. Future general practitioner: learning and teaching
(by a working party of the RCGP). London:
British Medical Association, 1972. 10.50.
58. Weston WW. Selected references for teaching and learning in family medicine. (reprinted
from a series of five articles in CANADIAN FAMILY PHYSICIAN) 1981. (reprints available from
CANADIAN FAMILY PHYSICIAN, 4000 Leslie St.,
Willowdale, Ontario, M2K 2R9.) $2.

EMERGENCY MEDICINE
59. Cain HD. Flint's emergency treatment and
management. 6th ed. Philadelphia: Saunders,
1980. $29.05.
OR
60. Rosen P, Baker FJ 2d, Braen GR, et al, eds.
Emergency medicine: concepts and clinical
practice. St. Louis: Mosby, 1983. $144.25.
OR
61. Wilkins EW Jr, Dineen JJ, Moncure AC, et
al, eds. Textbook of emergency medicine. 2nd
ed. Baltimore: Williams & Wilkins, 1983.
$97.50.

62. Driesbach RH. Handbook of poisoning: prevention, diagnosis and treatment. 1 Ith ed. Los
Altos, Calif: Lange Medical, 1983. $14.30.
OR
63. Haddad L, Winchester J. Clinical management of poisoning and drug overdose. Philadelphia: Saunders, 1982. $102.30.
64. Committee on Trauma, American College of
Surgeons. Early care of the injured patient. 3rd
ed. Philadelphia: Saunders, 1982. $39.60.
65. McIntyre KM, Lewis AJ, eds. Textbook of
advanced cardiac life support. Dallas: American
Heart Association, 1983. (available from the
Ontario Heart Foundation, 576 Church St.,
Toronto, Ontario, M4Y 2S1.) $9.50.

ETHICS
66. Bayles M. Professional ethics. Belmont,
Calif: Wadsworth, 1982. $15.
OR
67. Brody H. Ethical decisions in4nedicine. 2nd
ed. Boston: Little, Brown, 1981. $24.95.
OR
68. McLean S, Maher G. Medicine, morals and
the law. Aldershot, Hampshire: Gower, 1983.
$34.50.
69. Canadian Medical Association. Code of
ethics. Ottawa: CMA, 1982. Free.

FAMILY, MARRIAGE
AND SEXUALITY
70. Christie-Seely J, ed. Working with the family in primary care. New York: Praeger, 1984.
$40.55.
OR
71. Doherty WJ, Baird MA. Family therapy and
family medicine. New York: Guilford Press,
1983. $30.
72. Freedman GR. Sexual medicine. Edinburgh:
Churchill Livingstone, 1984. $29.50.
OR
73. Kolodny RC, Masters WH, et al. Textbook
of sexual medicine. Boston: Little, Brown,
1979. $29.25.
74. Huygen FJ. Family medicine: the medical
life history of families. New York: Brunner/Mazel, 1982. $28.
75. Wallerstein JS, Kelly JB. Surviving the
breakup: how children and parents cope with divorce. New York: Basic, 1982. $12.50.

FAMILY MEDICINE
76. Fry J, ed. Primary care. New York: Heinemann, 1980. $59.95.
OR
77. Geyman JP. Family practice: foundation of
changing health care. New York: Appleton-Century-Crofts, 1979. $45.15.
78. Rakel RE, Conn HF, eds. Textbook of family practice. 3rd ed. Philadelphia: Saunders,
1984. $118.15.
OR
79. Taylor RB, ed. Family medicine: principles
and practice. 2nd ed. New York: Springer,
1983. $88.30.
Part 1 of Family medicine: principles and practice is available in a student edition:
80. Taylor RB, ed. Fundamentals of family
medicine. New York: Springer, 1983. $45.
81. Cormack JJ, Marinker M, Morrell D, eds.
Practice: a handbook of primary medical care.
Brentford, Middlesex: Kluwer, 1982. $86.
82. Fry J. Common diseases. 3rd ed. Lancaster:
MTP Press, 1983. $40.
83. Geyman JP, ed. Archives of family practice.
Vol. 2. New York: Appleton-Century-Crofts,
1981. $58.95.
2165

PNAW*

CHDEa
71id

'

oph

imniO

ACTWN:
Aetaminophen is an analgesic and antpyre

rTONS:

Panador Acetaminophen is indicated for the reif of

pain and fever in various conditions incuding the
symptomatic treatment of colds.
1n11ONS:
Hyprsnsiivtyto acetaminophen.

co

-DO

ERES

hI contrast to salicyltes, gastroinestin irrilation

I a rare hyperrarely occurs wih acea
ssaity remaon occurs, discontinue te drg
Hypersensitivt is maniesd by rash or urticaia.
ur use of acemninophen has shown to prduce
a slt increase in prothrmbi te in pabents
rc n oral anrticoagulans but the dinical signj
cance o this effect is not clear.

cAUONS AMD TREATMENT OF OVDOSE:

The majority of patbents who have ingested an overdose large enough to cause hepatic toxicity have
early symptoms However, since there are excepo,
in cases of suspected acetamiophen ovedose, begin
specific anbtdol therapy as soon as possible. Maintain supportive treatment throughout management of
overdose as indicated by the resuts of acetaminophen
plsma lves, liver function tests and oter clinical
laboratory tests.
N-acetylcysteine as an anidote for acetaminophen
overdose is recommended and is available in oral
and parenteral dosage foms More detailed information on the treatment of acetaminophen overdose
with N-ac e ine in its oral and parenteral dosage
forms is available from the manufacturers (Mucomyst,
BrstolMyers Canada Limited trademark for its
brand of oral N-acetylcysteine; Parvolex, Glaxo Canada
Ltd. trademark for its brand of parenteral Ncey
cysteine), or conbta your nearest Poison ControV

Information Centre.
DOSAGE:
Based on Hbgt
10-15 mg/kg evey 4 to 6 hous, not to exceed
65 mg/kg in 24 hours.

BasedemAV
AV

ShDos

40 mg
Newbom to under 4 months
80 mg
4 monhs to under 12 months
120 mg
12 months to under 2 years
160 mg
2 and 3 years
240 mg
4 and 5 years
320 mg
6, 7 and 8years
400 mg
9 and 10 years
480 mg
II and 12 years
640 mg
13 years and older
Dosage may be repeated 4 to 5 times, not to exceed
5 doses in 24 hours.
SUPPLID:
Panadol Drops: Each 0.8 mL contains 80 mg acetamiophen in a deep red liquid vehicle with a slightly
bitter fruit flavoured taste. halable in amber botles
otaining 15 mLt and 25 mLtand a calibrated
diropper.
Panador Elixir Each 5 mL oontains 120 mg acetaminophen in a fruit flavoured red vehicle Available in
amber bottes containing 100 mLt.
Panadol Pleasant btsng Chewable Tables 80 mg:
Each round, pink tablet scored one side and enrWaved
Panadol the other side, contains 80 mgacetamnophen. AIWaible in amber bottes of 24ttablets

Sterling Products Division of Sterling Drug Ltd.,

Aurora, Ontario 140 3H6

84. Geyman JP, ed. Archives of family practice.

Vol. 3. Norwalk, Conn: Appleton-CenturyCrofts, 1982. $53.45.
85. Kushner KP, ed. Critical issues in family
practice: cases and commentaries. New York:
Springer, 1982. $29.
86. McWhinney IR. An introduction to family
medicine. New York: Oxford Univ. Press,
1981. $12.95.
87. Medalie JH, ed. Family medicine: principles
and applications. Baltimore: Williams & Wilkins, 1978. $23.Q5.
88. Shires DB, Hennen BK. Family medicine: a
guidebook for practitioners of the art. New
York: McGraw-Hill, 1980. $31.20.
89. Stephens GG. The intellectual basis of family practice. Tucson: Winter, 1982. $28.

106. Goroll AH, May LA, Mulley AG. Primary

care medicine. Philadelphia: Lippincott, 1981.
$49.50.
107. Harvey AM, Johns RJ, McKusick VA, et
al, eds. The principles and practice of medicine.
21st ed. New York: Appleton-Century-Crofts,
1984. $64.85.
OR
108. Petersdorf RG, Adams RD, Braunwald E,
et al, eds. Harrison's principles of internal medicine. 10th ed. New York: McGraw-Hill, 1983.

$97.50.
OR
109. Weatherall DJ, Ledingham JG, Warrell
DA, eds. Oxford textbook of medicine. Oxford:
Oxford Univ. Press, 1983. $99.
OR
110. Wyngaarden JB, Smith LH Jr, eds. Cecil
GENETICS
textbook of medicine. 16th ed. Philadelphia:
90. Roberts JA, Pembrey ME. An introduction Saunders, 1982. $99.
to medical genetics. 7th ed. New York: Oxford
Univ. Press, 1978. $28.50.
LABORATORY MEDICINE
OR
Biochemical values in clini91. Thompson JS, Thompson MW. Genetics in 111. Eastham RD.
6th
ed. Bristol: John Wright,
cal
medicine.
medicine. 3rd ed. Philadelphia: Saunders, 1980. 1978. $15.75.
$26.35.
OR
112. Wallach JB. Interpretation of diagnostic
GERIATRICS see
a handbook synopsis of laboratory meditests:
AGING AND GERIATRICS
cine. 3rd ed. Boston: Little, Brown, 1978.
$20.75.
GRIEF, DEATH AND
113. Ravel R. Clinical laboratory medicine. 4th
DYING, AND PALLIATION
ed.
Chicago: Year Book, 1984. $30.25.
92. Kubler-Ross E. On death and dying. New
York: Macmillan, 1969. $5.95.
93. Kubler-Ross E. Living with death and MEDICOLEGAL ISSUES
dying. New York: Macmillan, 1981. $16.25.
114. Emson HE. The doctor and the law.
94. Parkes CM. Bereavement: studies of grief in Toronto: Macmillan, 1979. $10.95.
adult life. Middlesex, England: Penguin, 1972. OR
$6.95.
115. Marshall TD. The physician and Canadian
95. Doyle D, ed. Palliative care: the manage- law. 2nd ed. Toronto: Carswell, 1979. $24.50.
ment of far-advanced illness. Philadelphia: 116. Rozovsky LE. The Canadian patient's book
Charles Press, 1984. $45.85.
of rights. Toronto: Doubleday, 1980. $9.95.
OR
96. Saunders CM, ed. The management of terminal disease. Chicago: Year Book, 1979. NURSING
117. Freeman RB, Heinrich J. Community
$41.30.
health nursing practice. 2nd ed. Philadelphia:
OR
Saunders, 1981. $24.25.
97. Wilkes E, ed. The dying patient: the medical OR
management of incurable and terminal illness. 118. Stanhope M, Lancaster J. Community
Lancaster, England: MTP Press, 1982. $32.50. health nursing-process and practice for prohealth. St. Louis: Mosby, 1984. $42.
GROWTH AND DEVELOPMENT moting
119. Murray RB, Zentner JP. Nursing assess98. Erikson EH. The life cycle completed: a re- ment and health promotion through the life span.
view. New York: Norton, 1982. $15.95.
3rd ed. Englewood Cliffs, NJ: Prentice-Hall,
99. Fraiberg SH. Magic years. New York: 1985 (in prep).
Scribner, 1959. $9.50.
OR
100. Hofmann AD, Greydanus DE, eds. Ado- 120. Pender NJ. Health promotion in nursing
lescent medicine. Reading, Mass: Addison- practice. Norwalk, Conn: Appleton-CenturyWesley, 1983. $49.50.
Crofts, 1982. $26.75.
101. Illingworth RS. The development of the in- 121. Freidman MM. Family nursing: dteory and
fant and young child. 8th ed. Edinburgh: Chur- assessment. New York: Appleton-Centurychill Livingstone, 1983. $29.50.
Crofts, 1980. $23.55.
102. Lidz T. The person: his and her development throughout the life cycle. New York:
NUTRITION
Basic, 1976. $18.95.
103. Lowrey GH. Growth and development of 122. Goodhart RS, Shils ME, eds. Modern nuchildren. 7th ed. Chicago: Year Book, 1978. trition in health and disease. 6th ed. Philadelphia: Lea & Febiger, 1980. $59.50.
$34.25.
OR
123. Schneider HA, Anderson CE, Coursin DB,
INTERNAL MEDICINE
104. Barker LR, Burton JR, Zieve PD. Princi- eds. Nutritional support of medical practice. 2nd
ples of ambulatory medicine. Baltimore: Wil- ed. Philadelphia: Harper & Row, 1983. $44.85.
124. Committee for the Revision of the Dietary
liams & Wilkins, 1982. $101.40.
Standard for Canada. Recommended nutrient inOR
105. Branch WT. Office practice of medicine. takes for Canadians. Ottawa: Health and Welfare Canada, 1983. (Catalogue No. H58Philadelphia: Saunders, 1982. $104.
OR

26/1983E.) $8.95.
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

125. Ontario Dietetic Association, Ontario Hospital Association. Diet manual. 5th ed. Don
Mills, Ontario: OHA, 1982. $25 (members);
$35 (non-members).

OBSTETRICS
AND GYNECOLOGY
126. Glass RH, ed. Office gynecology. 2nd ed.
Baltimore: Williams & Wilkins, 1981. $50.70.
OR
127. McPherson A, Anderson A, eds. Women's
problems in general practice. Oxford: Oxford
Univ. Press, 1983. $35.75.
128. Benson RC, ed. Current obstetric and gynecologic diagnosis and treatment. 5th ed. Los
Altos, Calif: Lange Medical, 1984 (in prep).

$32.50.
129. Oxorn H, Foote WR. Human labor and
birth. 4th ed. New York: Appleton-CenturyCrofts, 1980. $26.
130. Pritchard JA, MacDonald PC. Williams
obstetrics. 17th ed. New York: Appleton-Century-Crofts, 1984 (in prep). $91.65.

OCCUPATIONAL AND
INDUSTRIAL MEDICINE
131. Levy BS, Wegman DH, eds. Occupational
health: recognizing and preventing work-related
diseases. Boston: Little, Brown, 1983. $35.50.
OR
132. Rom WN, ed. Environmental and occupational medicine. Boston: Little, Brown, 1983.
$99.

ONCOLOGY
133. Cassileth BR, Cassileth PA, eds. Clinical
care of the terminal cancer patient. Philadelphia:
Lea & Febiger, 1982. $30.
134. Rubin P, ed. Clinical oncology for medical
students and physicians: a multidisciplinary approach. 6th ed. Rochester: University of Rochester School of Medicine and Dentistry, 1983.
(available from National Cancer Institute, 1001130 Bloor St. W., Toronto, Ontario, MSS 2V7.)
Free to physicians.

OPHTHALMOLOGY
135. Newell FW. Ophthalmology: principles
and concepts. 5th ed. St. Louis: Mosby, 1982.

$48.50.
OR
136. Vaughan D, Ashbury T. General ophthalmology. 10th ed. Los Altos, Calif: Lange Medical, 1983. $22.10.
137. Glasspool M. Problems in ophthalmology.
Lancaster: MTP Press, 1982. $22.50.

ORTHOPEDICS
138. Adams JC. Outline of fractures, including
joint injuries. 8th ed. Edinburgh: Churchill Livingstone, 1983. $19.50.
OR
139. Connolly JF, ed. DePalma's The management of fractures and dislocations: an atlas. 3rd
ed. Philadelphia: Saunders, 1981. 2 vols.
$158.40.
140. Adams JC. Outline of orthopaedics. 9th ed.
Edinburgh: Churchill Livingstone, 1981.
$29.50.
OR
141. Cyriax J. Textbook of orthopaedic medicine. Vol. 1. Diagnosis of soft tissue lesions. 8th
ed. London: Bailliere Tindall, 1982. $63.50.
OR
142. Ramamurti CP, Tinker RV, eds. Orthopaedics in primary care. Baltimore: Williams &
Wilkins, 1979. $54.65.
OR
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

143. Salter RB, ed. Textbook of disorders and

injuries of the musculoskeletal system. 2nd ed.
Baltimore: Williams & Wilkins, 1983. $51.65.
144. Cailliet R. Low back pain syndrome. 3rd
ed. Philadelphia: F. A. Davis, 1981. $16.90.

OTORHINOLARYNGOLOGY

Attivan*

145. DeWeese DD, Saunders WH. Textbook of

otolaryngology. 6th ed. St. Louis: Mosby, 1982.
$48.50.

A compatible
benzodiazepine

PATHOLOGY

AVAILABILITY: Ativan Oral Tablets: White, round, flat

tablets containing 0.5mg lorazepam. White, oblong,
scored tablets containing 1 mg lorazepam. White, ovoid,
scored tablets containing 2mg lorazepam. Ativan Sublingual Tablets: White, round, flat tablets (engraved with W
on one side and 1 on the other side) containing 1 mg
lorazepam. Blue, round, flat tablets (engraved with W on
one side and 2 on the other side) containing 2mg
lorazepam. Ativan Injection: Ativan Injection is available
in 1 mL ampoules of 4mg per mL. The ampoules should
be refrigerated and protected from light. Do not use if
solution is discolored or contains a precipitate.
INDICATIONS: Ativan is useful for the short-term
relief of manifestations of excessive anxiety in
patients with anxiety neurosis.
CONTRAINDICATIONS: Ativan is contraindicated
in patients with known hypersensitivity to benzodiazepines and in patients with myasthenia gravis
or acute narrow angle glaucoma.
DOSAGE: The dosage of ATIVAN must be individualized and carefully titrated in order to avoid
excessive sedation or mental and motor impairment. As with other anxiolytic sedatives, it is not
recommended to prescribe or administer ATIVAN
for periods in excess of six weeks, without followup and establishing the need for more prolonged
administration in individual patients.
Usual Adult Dosage: The recommended initial
adult daily dosage is 2 mg in divided doses of
0.5 mg. 0.5 mg and 1.0 mg. or of 1 mg and 1 mg.
The daily dosage should be carefully increased or
decreased by 0.5 mg dependirig upon tolerance
and response. The usual daily dosage is 2 to 3 mg.
However, the optimal dosage may range from 1 to
4 mg daily in individual patients. Usually. a daily
dosage of 6 mg should not be exceeded.
Elderly and Debilitated Patients: The initial daily
dose in these patients should not exceed 0.5 mg
and should be very carefully and gradually adjusted. depending upon tolerance and response.
PRECAUTIONS: Use in the Elderly: Elderly and
debilitated patients, or those with organic brain
syndrome. have been found to be prone to CNS
depression after even low doses of benzodiazepines. Therefore, medication should be initiated in
these patients with very low initial doses. and
increments should be made gradually, depending
on the response of the patient. in order to avoid
oversedation or neurological impairment.
Dependence Liability: Ativan should not be
administered to individuals prone to drug abuse.
Caution should be observed in patients who are
considered to have potential for psychological
dependence. It is suggested that the drug should
be withdrawn gradually if it has been used in high

146. Anderson WA, Scotti WA. Synopsis of pathology. 10th ed. St. Louis: Mosby, 1980.
$39.25.
OR
147. Robbins SL, Angell M, et al. Basic pathology. 3rd ed. Philadelphia: Saunders, 1981.
$43.50.

PATIENT EDUCATION
148. Bille DA, ed. Practical approaches to patient teaching. Boston: Little, Brown, 1981.
$17.95.
OR
149. Redman BK. The process of patient teaching in nursing. 5th ed. Toronto: Mosby, 1984.
$22.25.
150. Griffith HW. Instruction for patients. 3rd
ed. Philadelphia: Saunders, 1982. $33.35.

PEDIATRICS see CHILD CARE

PHARMACOLOGY
AND THERAPEUTICS
151. American Medical Association. Department of Drugs. AMA drug evaluations. 5th ed.
Philadelphia: Saunders, 1983. $84.50.
OR
152. Gilman AG, Goodman LS, et al, eds.
Goodman and Gilman's The pharmacological
basis of therapeutics. 6th ed. New York: Macmillan, 1980. $67.50.
153. Campbell JW, Frisse M, eds. Manual of
medical therapeutics. 24th ed. (Washington University, Dept. of Medicine). Boston: Little,
Brown, 1983. $21.95.
OR
154. Krupp MA, Chatton MJ, eds. Current medical diagnosis and treatment. Los Altos, Calif:
Lange Medical, 1984. $32.50.
OR
155. Rakel RE, ed. Conn's current therapy. Phi-

ladelphia: Saunders, 1984. $55.45.

156. American Pharmaceutical Association.
Handbook of nonprescription drugs. 7th ed.
Washington, DC: APA, 1982. $45 (U.S.).
157. Martindale WA, ed. The extra pharmacopoeia. 28th ed. London: Pharmaceutical Press,
1982. $140.
158. Wilkes E, ed. Long-term prescribing: drug
management of chronic disease and other problems. Winchester, Mass: Faber & Faber, 1982.
$29.95.

PHYSICAL MEDICINE
AND REHABILITATION
159. Kottke FJ, Stillwell GK, Lehmann JF. Krusen's handbook of physical medicine and rehabilitation. 3rd ed. Philadelphia: Saunders, 1982.

$65.35.
OR
160. Rusk HA. Rehabilitation medicine. 4th ed.
St. Louis: Mosby, 1977. $68.25.
OR
161. Washburn KB. Physical medicine and re-

(loraz.pam)

dosage.
Use in Mental and Emotional Disorders: Ativan is
not recommended for the treatment of psychotic
or depressed patients. Since excitement and other
paradoxical reactions can result from the use of
these drugs in psychotic patients, they should not
be used in ambulatory patients suspected of having
psychotic tendencies.
ADVERSE EFFECTS: The side effect most frequently reported was drowsiness. Other reported
side effects were dizziness, weakness, fatigue and
lethargy, disorientation, ataxia, anterograde
amnesia, nausea, change in appetite, change in
weight, depression, blurred vision and diplopia,
psychomotor agitation, sleep disturbance, vomiting, sexual disturbance, headache, skin rashes,
gastrointestinal, ear, nose and throat, musculoskeletal and respiratory disturbances.
Full product intormation available on request.

Wyeth
M j

m
Wyeth Ltd., Downsview,
Ontario M3M 3A8

PMRC

2167

Refinement
in Contraception
Prescribing Information
Indication: Conception control
Contraindications: Patients with thrombophlebitis, thromboembolic disorders, or a history of these conditions; cerebrovascular disorders; myocardial infarction; active liver disease;
history of cholestaticjaundice. Patients with known or
suspected carcinoma of the breast; estrogen-dependent
neoplasia; undiagnosed abnormal vaginal bleeding. During the
period a mother is breast-feeding an infant, or where
pregriancy is suspected or diagnosed. Patients with diplopia or
any ocular lesion arising from ophthalmic vascular disease, such
as partial or complete loss of vision or defect in visual fields, and
patients with classical migraine.
Wamings: Discontinue medication at the earliest manifestations
of: thromboembolic disorders such as: thrombophlebitis,
pulmonary embolism, cerebro-vascular disorders, myocardial
ischemia, mesenteric thrombosis, and retinal thrombosis, visual
defects, partial or complete; proptosis, diplopia, papilledema,
ophthalmic vascular lesions, or severe headache of unknown
etiology. Fetal abnormalities have been reported to occur in the
offspring of women who have taken estrogen-progestogen
combinations in early pregnancy. Rule out pregnancyas soon as
it is suspected. This drug may cause fluid retention. Conditions
such as epilepsy, asthma, and cardiac or renal dysfunction
require careful observation. In women with predisposing
factors for coronary artery disease (such as cigarette smoking,
hypertension, hypercholesterolemia, obesity, diabetes, history
of preeclamptic toxemia, and increasing age) oral contraceptives
have been reported as an additional risk factor. After the age of
40 years, for purposes of fertility control, oral contraceptives
should be considered only in exceptional circumstances and
when the risk/benefit ratio has been carefully weighed by both
the patient and the physician.
Precautions: Before oral contraceptives are used, a thorough
physical examination should be made including a blood
pressure determination. Breasts, liver, and pelvic organs should
be examined, and a Papanicolaou smear should be taken. The
first follow-up examination should be done within six months
after oral contraceptives are prescribed. Thereafter, examinations
should be made at least once a year. At each annual visit,
examination should include those procedures outlined above
that were done at the initial visit. Patients who have had
jaundice should be given oral contraceptives only with great
care and under close observation. If th?re is a clear-cut history
of cholestaticjaundice, especially if it occurred during
pregnancy, other methods of contraception should be
prescribed. The development of severe generalized pruritus or
icterus requires that the medication be withdrawn until the
problem is resolved. If thejaundice should prove to be
cholestatic in type, the use of oral contraceptives should not be
resumed. In patients taking oral contraceptives, changes in the
composition of the bile mayoccur and an increased incidence of
gallstones has been reported. Hepatic nodules ladenoma and
focal nodular hyperplasia) have been reported, particularly in
long-term users of oral contraceptives. Although these lesions
are uncommon, they have caused fatal intra-abdominal
hemorrhage and should be considered in women presenting
with an abdominal mass, acute abdominal pain, or evidence of
intra-abdominal bleeding. Patients with essential hypertension
may be given the drug but only under close supervision. If a
significant elevation of blood pressure in previously normotensive
or hypertensive subjects occurs at any time during the
administration of the drug, cessation of medication is necessary.
Diabetic patients, or those with a family history of diabetes,
should be observed closely to detect any alterations in
carbohydrate metabolism. Patients predisposed to diabetes
who can be kept under close supervision may be given oral
contraceptives. Young diabetic patients whose disease is of
recent origin, well-controlled, and not associated with
hypertension or other signs of vascular disease such as ocular
fundal changes, should be closely observed. In metabolic or
endocrine diseases and when metabolism of calcium and
phosphorus is abnormal, careful clinical evaluation should
precede medication and a regular follow-up is recommended.
Estrogen-progestogen combinations may cause an increase in
plasma lipoproteins and should be administered with caution to
women known to have preexistent hyperlipoproteinemia.
Although oral contraceptive use has not been shown to
increase the risk of developing breast cancer, particular
attention should be paid to women who have an immediate_
family history of this disease and are therefore more prone to its
development. Careful monitoring is mandatory because, if a
breast cancer should develop, estrogen-containing drugs may
cause a rapid progression if the malignancy is hormonedependent. Specialjudgment should be used in prescribing oral
contraceptives for women with fibrocystic disease of the breast
due to diagnostic difficulties. Persistent irregular vaginal
bleeding requires special diagnosticjudgment to exclude the
possibility of pregnancy or neoplasm. If these can be excluded,
giving the patient a product containing a higher dosage of
estrogen generally will correct the problem. Patients with
fibroids (leiomyomata) should be carefully observed. Sudden
enlargement, pain, or tenderness require discontinuance of
medication. In general, women in the later reproductive years
gradually assume an increasing risk of circulatory and metabolic
complications which becomes more prominentat 35 to 40years
of age. In view of this, closer observation, shorter duration of
oral contraceptive use, and avoidance of cigarette smoking is
advisable. Alternatively, adoption of other means of birth
control should be considered for this age group. Oral
contraceptives may mask the onset of the climacteric. Patients
with a history of emotional disturbances, especially the
depressive type, are more prone to have a recurrence of
depression while taking oral contraceptives. In cases of serious
recurrence, a trial of an alternate method of contraception
should be mnade which may help to clarify the potential
relationship. The following laboratorytest results should not be

considered reliable unless oral contraceptive therapy has been

discontinued for 2 to 4 months because therapy may alter the
following determinations and possibly mask underlying disease:
liver function tests; coagulation tests; thyroid function tests;
adrenocortical function tests; reproductive endocrine profile
changes. In other tests, HDL-cholesterol values were not
significantlyaltered, total cholesterol and triglycerides increased
slightly, while serum folate was decreased. There is no
deterioration in oral glucose tolerance or insulin responses.
Women on the triphasic studies generally remained normotensive. Renin activity and renin-substrate concentration
increased while renin concentration decreased slightly. Pathologists should be advised of oral contraceptive therapy when
specimens obtained from surgical procedures are submitted for
examination. After discontinuing oral contraceptive therapy,
the patient should await the resumption of the usual ovulatory
cycles before attempting to become pregnant. An alternate

contraceptive method should be used during this time. Women

having a history of oligomenorrhea, secondary dmenorrhea, or
irregular cycles may remain anovulatory or become amenorrheal
following estrogen-progestogen combination therapy.
Amenorrhea, especially if associated with breast secretion, that
continues for 6 months or more after oral contraceptive use,
warrants a careful assessment of hypothalamic-pituitary
function. Retrospective studies have reported an increased risk
of post-surgery thromboembolic complications in oral contraceptive users. If feasible, oral contraceptives should be
discontinued and a non-hormonal method substituted at least
one month prior to elective major surgery. Oral contraceptives
should not be resumed until at least two weeks after hospital
discharge following surgery. Contact lens wearers who develop
visual changes or changes in lens tolerance should be assessed
by an ophthalmologist and temporary or permanent cessation
of wear considered. Concomitant treatment with barbiturates,
rifampicin, phenylbutazone, or phenytoin has been reported to
reduce the efficacy of oral contraceptives and increase the
incidence of breakthrough bleeding.
Adverse reactions: An increased risk of the following serious
adverse reactions has been associated with the use of oral
contraceptives: thrombophlebitis; pulmonary embolism; mesenteric thrombosis; neuro-ocular lesions, eg. retinal thrombosis
and optic neuritis; myocardial infarction; cerebral thrombosis;
cerebral hemorrhage; hypertension; benign hepatic tumors; gall
bladder disease; congenital anomalies. The following adverse
reactions also have been reported in patients receiving oral
contraceptives; nausea and vomiting; gastrointestinal symptoms;
breakthrough bleeding; spotting; change in menstrual flow;
dysmenorrhea; amenorrhea; temporary infertility; edema;
chloasma; melasma; breast changes; change in weight;
endo-cervical hyperplasias; possible diminution in lactation;
cholestaticjaundice; migraine; increase in size of uterine
leiomyomata; rash; mental depression; reduced tolerance to
carbohydrates; vaginal candidiasis; premenstrual-like syndrome;
intolerance to contact lenses; change in corneal curvature;
cataracts; changes in libido; chorea; changes in appetite;
cystitis-like syndrome; headache; nervousness; dizziness; hirsutism; loss of scalp hair, erythema multiforme; erythema
nodosum; hemorrhagic eruption; vaginitis; porphyria; impaired
renal function.
Dosage and administration: TRIPHASIL 21 tablet regimen:
Each cycle consists of 21 days on medication and 7-day interval
without medication (three weeks on, one week off). The 21-day
regimen is comprised of the first six days of yellow tablets,
followed by five days of orange tablets, followed by ten days of
white tablets. For the first cycle of medication, the patient is
instructed to take one Triphasil tablet daily for 21 consecutive
days beginning on Day 5 of her menstrual cycle. (The first day of
menstrual flow is considered Day 1.) The tablets are then discontinued for seven days (one week). Withdrawal bleeding should
usually occur during the period that the patient is off the tablets.
TRIPHASIL 28 tablet regimen: Each cycle consists of 21 days of
Triphasil tablets followed by 7 days of inert tablets (three weeks
on Triphasil, one week on inert tablets). The 28 day regimen is
comprised of the first six days of yellow tablets, followed by five
days of orange tablets, followed by ten days of white tablets,
followed by seven days of inert pink tablets. For the first cycle of
medication, the patient is instructed to take one tablet for 28
consecutive days beginning on Day S of her menstrual cycle.
(The first day of menstrual flow is considered Day 1.( Withdrawal
bleeding should usually occur during the week the patient is
taking the pink inert tablets.
Availability: Triphasil tablets are available in 21-day regimen
and 28-day regimen packages. Each package contains three
different microgram dose combinations of d-norgestrel (as the
dl-racemate( and ethirnyl estradiol in the following manner. Days
1-6: Each yellow tablet contains 50 pg d-norgestrel (as 100 pg
of the dl-racemate( plus 30 pAg ethinyl estradiol. Days 7-1 1: Each
orange tablet contains 75 pg d-norgestrel (as 150 jig of the
dl-racemate( plus 40 pg ethinyl estradiol. Days 12-2 1: Each
white tablet contains 125 p1g d-norgestrel (as 250 pg of the
dl-racematel plus 30 pg ethinyl estradiol. In the 28-day regimen
package, each pink tablet taken on days 22-28 contains inert
ingredients. All tablets have a "W' on one face and a "T" on the
other face.
References
1. Product Monograph.
2. Data on file.
3. Gaspard, U.J., Romus, M.A., Gillain, D. "Comparative study of
lipid metabolism and endocrine function in women receiving
levonorgestrel- and desogestrel-containing oral contraceptives,"
Advances in Fertilitycontrol and the treatment of Sterility ed.
R. Rolland et al., (Lancaster: MTP Press, 1983(, p. 82.
4. Allen, H. "Multicenter Clinical Evaluation of Triphasil in
Canada," New Considerations in Oral Contraception,
(New York: Biomedical Information Corporation Publications,

19821, p.217.
5. Data on file.
Product Monograph available to physicians and pharmacists
on request.

Wyeth
|i
^ A

Wyeth Ltd.

habilitation. 2nd ed. Garden City, NY: Medical

Examination, 1981. $24.70.

PHYSIOLOGY
162. Ganong WF. Review of medical physiology. 11th ed. Los Altos, Calif: Lange Medical,
1983. $26.
OR
163. Guyton AC. Textbook of medical physiology. 6th ed. Philadelphia: Saunders, 1981.

$60.65.

PRACTICE MANAGEMENT
AND RECORDS
164. Aluise JJ. The physician as manager.
Bowie, MD.: Charles Press, 1980. (available
from STFM, 1740 W. 92nd St., Kansas City,
MO. 64114.) $29.95 (U.S.).
OR
165. Lawson JG, McConnell JW. Starting and
managing your practice-a guidebook for physicians. Cambridge, Mass: Oelgeschlager, Gunn
& Hain, 1983. $31.25.
OR
166. McCue JD. Private practice: surviving the
first year. Lexington, Mass: Collamore Press,
1982. $19.95.
167. Canadian Council on Hospital Accreditation. Standards for accreditation of Canadian
health care facilities. Ottawa: CCHA, 1983.

$14.
168. The College of Family Physicians of Canada. Family practice manual: a handbook on
practice management. 2nd ed. Toronto: CFPC,
1981. $12.
169. The College of Family Physicians of Canada. Manual for the College office record.
Toronto: CFPC, 1977. $4.

PREVENTIVE MEDICINE
170. Gray M, Fowler G, eds: Preventive medicine in general practice. Oxford: Oxford Univ.
Press, 1983. $35.75.
171. Last JM, ed. Maxcy-Rosenau public health
and preventive medicine. 11th ed. New York:
Appleton-Century-Crofts, 1980. $104.80.
172. Patterns of Practice and Health Care Delivery Committee, The College of Family Physicians of Canada. Health maintenance guide.
Toronto: CFPC, 1983. Free to members.
173. Task Force on the Periodic Health Examination. Periodic health examination. Ottawa:
Health and Welfare Canada, 1980. (Catalogue
No. H39-3/1980E.) $18.50.
174. Taylor RB, ed. Health promotion: principles and clinical applications. Norwalk, Conn:
Appleton-Century-Crofts, 1982. $52.35.

PSYCHOLOGICAL PROBLEMS
175. Dubovsky SL, Weissberg MP. Clinical
psychiatry in primary care. 2nd ed. Baltimore:
Williams & Wilkins, 1982. $22.10.
OR
176. Freeman AM 3d, Sack RL, Berger PA,
eds. Psychiatry for the primary care physician.
Baltimore: Williams & Wilkins, 1979. $32.50.
177. Kaplan HI, Sadock BJ. Modern synopsis of
comprehensive textbook of psychiatry/Il. 3rd
ed. Baltimore: Williams & Wilkins, 1981.

$46.45.
OR
178. Kolb LC, Brodie HK. Modern clinical psychiatry. 10th ed. Philadelphia: W. B. Saunders,
1982. $50.
179. Addiction Research Foundation. Diagnosis
and treatment of alcoholism for the primary care
physician. T'oronto: ARF, 1978. $1l.9f5.

North York, Ontario M3M 3A8

Registered Trademark

CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

180. American Psychiatric Association. Quick

reference to the diagnostic criteria from DSMIll. Washington, DC: APA, 1980. $16.45.
181. Bakal DA. Psychology and medicine: psychobiological dimensions of health and illness.
New York: Springer, 1979. $30.
182. Dubovsky SL. Psychotherapeutics in primary care. New York: Grune & Stratton, 1981.
$39.25.
183. Selye H. The stress of life. 2nd ed. New
York: McGraw-Hill, 1978. $9.50.

RADIOLOGY
184. Juhl JH. Paul and Juhl's essentials of roentgen interpretation. 4th ed. Philadelphia: Harper
& Row, 1981. $97.50.

RESEARCH
185. Fletcher RH, Fletcher SW, Wagner EH.
Clinical epidemiology: the essentials. Baltimore:
Williams & Wilkins, 1982. $22.10.
OR
186. Friedman GD. Primer of epidemiology.
2nd ed. New York: McGraw-Hill, 1979.
$23.70.
187. Geyman JP. Research in family practice.
New York: Appleton-Century-Crofts, 1978.
$14.50.
OR
188. Howie JG. Research in general practice.
London: Croom Helm, 1979. $19.
189. Colton T. Statistics in medicine. Boston:
Little, Brown, 1974. $29.75.
190. Gehlbach SH. Interpreting the medical literature: a clinician's guide. Lexington, Mass:
Collamore Press, 1982. $16.25.

SOCIAL WORK.
191. Turner FJ, ed. Differential diagnosis and
treatment in social work. 3rd ed. New York:
Macmillan, 1983. $42.95.

SOCIOLOGY
192. Bloom SW. The doctor and his patient: a
sociological interpretation. New York: Free
Press. 1965. $17.50.
193. Eisenberg L, Kleinman A, eds. The relevance of social science for medicine. Boston: D.
Reidel, 1981. $19.

SPORTS MEDICINE
194. Cantu RC. Sports medicine in primary
care. Lexington, Mass: Collamore Press, 1982.

$21.25.
OR
195. O'Donoghue DH. Treatment of injuries to
athletes. 4th ed. Philadelphia: Saunders, 1984.
$72.60.

SURGERY
196. Sabiston DC Jr, ed. Davis-Christopher
textbook of surgery. 12th ed. Philadelphia:
Saunders, 1981. $99.
OR
197. Schwartz SI, Hume D, et al, eds. Principles
of surgery. 4th ed. New York: McGraw-Hill,
1983. $97.50.
198. Wolcott MW, ed. Ambulatory surgery and
the basics of emergency surgical care. 6th ed.
Philadelphia: Lippincott, 1981. $60.

UROLOGY
199. Smith DR. General urology. 11th ed. Los
Altos, Calif: Lange Medical, 1984 (in prep).
$25.35.

WRITING
200. American Medical Association. Manual for
authors and editors: editorial style and manuCAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

script preparation. 7th ed. Los Altos, Calif:

Lange Medical, 1981. $11.05.
OR
201. Huth EJ. How to write and publish papers
in the medical sciences. Philadelphia: ISI Press,
1982. $15.60.
OR
202. McCaffery M. Writing that's worth reading: a practical guide for writers of medical articles. (reprinted from six articles in CANADIAN
FAMILY PHYSICIAN) 1980. (reprints available
from CANADIAN FAMILY PHYSICIAN, 4000 Leslie
St., Willowdale, Ontario, M2K 2R9.) $1.50.

GENERAL REFERENCE
203. Family Medicine Literature Index
(FAMLI). Published quarterly with an annual
cumulation by the World Organisation of National Colleges, Academies and Academic Associations of General Practitioners/Family Physicians (WONCA) in cooperation with the U.S.
National Library of Medicine. (distributed by
T;he College of Family Physicians of Canada.)
$70 (Cdn.) in Canada and U.S.A.; $80 in other
countries.
204. New Readings for General Practitioners.
Published annually by the Royal College of
General Practitioners, 14 Princes Gate, London, SW7 lPU. Free.
205. Abridged Index Medicus (AIM). Published
monthly by the U.S. National Library of Medicine. (distributed by Superintendent of Documents, U.S. Government Printing Office, Washington, D.C. 20402.) (annual cumulation
available separately.) $57.50 (U.S.)
206. Medical Subject Headings (MeSH) 1984.
Published annually by the U.S. National Library
of Medicine (address as above). $11.90 (U.S.)
207. Classification Committee, World Organisation of National Colleges, Academies and Academic Associations of General Practitioners/
Family Physicians (WONCA). ICHPPC-2defined (International Classification of Health
Problems in Primary Care). 3rd ed. Oxford: Oxford Univ. Press, 1983. $22.50.
208. The College of Family Physicians of Canada. Family medicine research: a current Canadian index. Toronto: CFPC. (published annually.) $10.
209. Ontario Medical Association. A health
sciences library basic manual for library staff in
small health care institutions. Toronto: ONA,
1982. $16.
210. Gray DJ, ed. The medical annual 1984.
The year book of general practice. Bristol: John
Wright, 1984. $35.
OR
211. Rakel RE, ed. Year book of family practice. Chicago: Year Book. (published annually.)

$52.50.
212. Dorland's illustrated medical dictionary.
26th ed. Philadelphia: Saunders, 1981. $47.45.
OR
213. Illustrated Stedman's medical dictionary.
24th ed. Baltimore: Williams & Wilkins, 1981.

$49.40.

JOURNALS
General Medicine (two of)
-British Medical Journal. Weekly. $113.10.
-Canadian Medical Association Journal. Bimonthly. $49.50.
-JAMA. Journal of the American Medical Association. Weekly. $76.80.
-Lancet. Weekly. $55.
-New England Journal of Medicine. Weekly.

$79.20.

;4napiox.
Indications. (naproxen sodium)
Relief of mild to moderately severe
pain, accompanied by inflammation such
as musculoskeletal trauma, post-dental
extraction, relief of post-partum cramping and dysmenorrhea.

Confralndicaffons.

Patients who have hypersensitivity to

it or in whom ASA or other nonsteroidal drugs induce asthma, rhinitis
or urticaria; in active peptic ulcer or
inflammatory disease of G.I. tract.

Wamings.
Not recommended in children under
16 years of age, pregnant or lactating
women, because safety and dose schedule have not been established.

Praufion&
Caution is advised, in patients taking
a coumarin-type anticoagulant, hydantoin, sulfonamide or sulfonylurea. Use
with caution in patients with impaired
renal function, compromised cardiac
function and patients whose overall
intake of sodium is markedly restricted.
(Each tablet contains approximately
25mg of sodium.)*
*Probenecid increases Anaprox plasma
levels and half-life.

Adverse Reactions.

GI.: nausea, heartburn, abdominal

discomfort, vomiting, constipation, dyspepsia, stomatitis, diarrhea, melena, gastrointestinal bleeding (occasionally
severe) and hematemesis.
C.N.S.: dizziness, headache, drowsiness, mental confusion, lightheadedness,
vertigo, inability to concentrate and
depression.
Special Senses: tinnitus, visual disturbances, and hearing disturbances.
Skin: itching (pruritus), skin eruptions, sweating, ecchyTnoses, skin rashes,
urticaria and purpura.
Cardiovascular: edema, palpitations,
and dyspnea were reported. In this class
of drugs, other reactions seen include
congestive heart failure, pyrexia, acute
renal disease, hematuria, jaundice, angioneurotic edema, thrombocytopenia,
eosinophilia, agranulocytosis, aplastic
anemia, hemolytic anemia and peptic
ulceration with bleeding and/or
perforation.

Availabilifty.

Anaprox (naproxen sodium) is available in blue filmcoated tablets of 275 mg

in a bottle of 100 tablets.

Dosage.

Initial dose: 2 tablets.

Thereafter: 1 tablet every 6-8 hours as
required.
Maximum daily dose: 5 tablets.

References.

1. Dingfelder J. Primary dysmenorrhea

treatment with prostaglandin inhibitors:
A review. Am J Obstet Gynecol 1981:

140:874-879.
2 Smith L. Naproxen sodium in dysmenorrhea: A Canadian clinical trial
Proceedings: Telemedical Symposium
"Prostaglandins and Dysmenorrhea.
"Sept. 10. 1980. Canada.
Product monograph available on request.

Syntex Inc.*
Mississauga, Ont./Montreal, Que.
*Reg. user ofall trademarks.

X~~

Faniily Medicine (two of)

-Australian Family Physician. Monthly. $60.
-Canadian Family Physician. Monthly. $18.
-Family Practice: An International Journal.
Quarterly. $69 (U.S.).
-Journal of Family Practice. Monthly. $48.
-Journal of the Royal College of General Practitioners. Monthly. $90.
-Practitioner. Monthly. $48.
Summary Journals (at least one)
-American Family Physician. Monthly. $48.
-Annals of Emergency Medicine. Monthly.
$60.
-Patient Care. 21/year. $60.
-Postgraduate Medicine. Monthly. $38.40.
-Primary Care. Quarterly. $34.80.
Drug Therapy (at least one)
-Drug and Therapeutics Bulletin. Bimonthly.
20.50.
-Medical Letter on Drugs and Therapeutics.
Bimonthly. $24.50 (U.S.)
Other Choices (optional)
-Family Systems Medicine. Quarterly. $32.
(U.S.)
-Journal of Medical Education. Monthly. $33.
-Medical Education. Bimonthly. $120.
-Union Medicale du Canada. Monthly. $50.

Maugham WS. Of human bondage. New York:

Penguin, 1963. $4.95.
Miller A. Death of a salesman. New York: Penguin, 1949. $2.95.
Moliere JB. Le malade imaginaire. New York:
French and European Pubns., 1964. $4.50.
Pasternak B. Dr. Zhivago. London: Fontana,
1961. $3.95.
Pirsig RM. Zen and the art of motorcycle maintenance. New York: Bantam, 1974. $3.95.
Plath S. The bell jar. London: Faber and Faber,
1963. $4.95.
Shaffer P. Equus. New York: Avon, 1977.
$2.50.
Shaw GB. The doctor's dilemma. Middlesex,
England: Penguin, 1957. $3.95.
Solzhenitsyn A. Cancer ward. Middlesex, England: Penguin, 1968. $5.95.
Thompson M. The cry and the covenant. New
York: New American Library, 1973. $1.95.
Tolstoy L. Anna Karenina. Middlesex, England:
Penguin, 1978. $5.95.
Tolstoy L. Death of fvan Ilych. New York: Bantam, 1981. $1.95.

INDEX BY AUTHOR
AND ABBREVIATED TITLE

APPENDIX-MEDICINE IN
LITERATURE
Cousins N, ed. The physician in literature.
Toronto: Saunders, 1982. $22.95.
Peschel ER, ed. Medicine and literature. New
York: N. Watson 1980. $16.85.
Trautmann J, Pollard C. Literature and medicine: an annotated bibliography. Rev. ed.
Pittsburgh, Pa.: University of Pittsburgh
Press, 1982. $26.
Albee E. Who's afraid of Virginia Woolf? New
York: New American Library, 1962. $3.95.
Atwood M. The edible woman. Toronto:
McClelland and Stewart Seal Books, 1969.

$3.95.
Baldwin J. Go tell it on the mountain. New
York: Dell, 1953. $1.95.
Camus A. The plague. Middlesex, England:
Penguin, 1948. $3.95
Cousins N. Anatomy of an illness. New York:
Bantam, 1981. $6.95.
de Beauvoir S. A very easy death. Middlesex,
England: Penguin, 1969. $3.50.
Dickens C. Pickwick papers. New York: Bantam, 1983. $4.95.
Eliot G. Middlemarch. Middlesex, England:
Penguin, 1965. $5.95.
Eliot TS. Cocktail party. London: Faber and
Faber, 1950. $5.75.
Kesey K. One flew over the cuckoo's nest. New
York: New American Library, 1962. $2.95.
Laurence M. The stone angel. Toronto: McClelland and Stewart Seal Books, 1968. $3.50.
Lear MW. Heartsounds. New York: Pocket
Books, 1980. $3.95.
LeBaron C. Gentle vengeance: an account of the
first year at Harvard Medical School. New
York: Penguin, 1981. $4.95.
Lewis S. Arrowsmith, New York: New American library, 1961. $2.50.
Mann T. Death in Venice and seven other
stories. New York: Random, 1963. $5.50.
Mann T. Magic mountain. New York: Random,
1969. $9.50.
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

Abridged Index Medicus (AIM) ........... 205

18
Ackerknecht E. A. .....................
1
Adams ......................
Adams J. C. ............... ...... 138, 140
Adams R. D .............................
108
Addiction Research Foundation ........... 179
Adolescent medicine ........................
100
Allergic diseases: diagnosis and
9
management .............................
Aluise J. J. ........................ ..... 164
AMA drug evaluations ...................... 151
Ambulatory pediatrics three ................ 24
Ambulatory surgery and the basics of
emergency surgical care ................. 198
American Academy of Pediatrics .......... 29
American Medical Association ....... 151, 200
American Pharmaceutical Association .... 156
American Psychiatric Association ......... 180
127
Anderson A . .............................
Anderson C. E . ............................. 123
12
Anderson J. E. .............................
Anderson W. A ............................. 146
Andrew's diseases of the skin .............. 37
Angell M. ...................... ....... 147
Approaches to teaching primary health
52
care .............................
Archives of family practice ............... 83, 84
136
Ashbury T .
.............................

Bernstein R. S .............................. 44
Bhaskar S. N. .............................
33
Bille D. A.
148
111
Biochemical values in clinical medicine
Bird B. R.
49
Blacklow R. S. ..............................
38
Bland C. J. ..............................
53
Bloom S. W. .............................
192
..............................

..............................

Braen G. R.
Branch W. T . .............................
Braunwald E. .............................
Brody H. ................... ..........
Brocklehurst J. C. ...........................
Brodie H. K .
Bursztajn H . .............................
Burton J. R . ..............................
Byme P. S.

60
105
108
67
2
178
41
104
50

Cailliet R. ..................... ........

Cain H. D. .......................... ....
Campbell J. W. .............................
Canadian Council on Hospital
Accreditation ..............................
Canadian family medicine: educational
objectives for certification in family
medicine ..............................
Canadian Medical Association ......... ....
(The) Canadian patient's book of rights ..
Cantu R. C. ..............................
Cape R. D. ..............................
Care of the high risk neonate .......... .....
Cassileth B. R ..............................
Cassileth P. A .............................
Cecil textbook of medicine ........... ......
Chatton M. J. .............................
Child care in general practice ......... .....
Christie-Seely J ..............................
Clinical anatomy .............................
Clinical anatomy for medical students
Clinical aspects of aging ............... .....
Clinical care of the terminal cancer
patient ................... ...........
Clinical diagnosis: A physiologic

144
59
153

..............................

.............................

..............................

approach ..............................
Clinical epidemiology: the essentials .....
Clinical geriatrics ............................
Clinical laboratory medicine .......... .....
Clinical management of poisoning and
drug overdose ..............................
Clinical oncology for medical students
and physicians .............................
Clinical psychiatry in primary care ........
Clinical thinking and practice: diagnosis
and decision in patient care ......... .....
Code of ethics ..............................
CoeR. M
.
(The) College of Family Physicians of
Canada .. . 7, 54, 168, 169, 172,
Colton T.
Committee for the Revision of the Dietary
Standard for Canada ......................
Committee on Trauma, American College
of Surgeons ..............................
Common diseases ............................
Common symptoms of disease
in children ..............................
Communicable and infectious diseases ...
Community health nursing practice .......
Community health nursing - process and
practice for promoting health ........ ...
Conn H. F.
Conn's current therapy .................. ....
..............................

.............................

167

54
69
116
194
3
28
133
133
110
154
25
70
10

11....
4

133
40
185
5
113

63
134
175
43
69
3

208
189

124
Baird M. A .
71
64
Baker F. J. ........................ ..... 60
82
181
Bakal D. A .
Balint M. ................... .......... 48
26
104
Barker L. R. .............................
32
Basic pathology ............................. 147
117
13
Basmajian J. V. .............................
66
Bayles M .
118
Bedside diagnostic examination ...........
39
78
Behrman R. E ............................. 22
Benenson A. S ............................. 30
155
128 Connolly J. F .............................. 139
Benson R. C. .............................
Bereavement: studies of grief in adult life
94 Control of communicable diseases in man ............
Berger J ...............19
Cormack J. J............ 51, 81
8
Berger P. A. ...............176 Counseling elders and their families ............
Bernstein L ...............44
Coursin D. B . ..............
123
.............................

.............................

.............................

..............................

2171

Easy to take

erudise E-50
(enteric-coated ketoprofen)

Piescribing information
THERAPEUTIC CLASSIFICATION:
Anti-inflammatory agent with analgesic
properties.
INDICATIONS: Treatment of rheumatoid
arthritis, ankylosing spondylitis and
osteoarthritis.
CONTRAINDICATIONS: Active peptic
ulcers or active inflammatory diseases of
the gastrointestinal tract; suppositories
should not be used in patients with any
inflammatory lesions of rectum or anus, or
a recent history of rectal or anal bleeding.
Hypersensitivity to the drug. Because of
the existence of cross sensitivity, Orudis
should not be given to patients in whom
acetylsalicylic acid and other non-steroidal anti-inflammatory drugs induce
symptoms of asthma, rhinitis or urticaria.
WARNINGS: In pmgnancy - Safety in
pregnant or nursing women has not been
determined and therefore is not recommended. Pregnant rats who received
ketoprofen 6 and 9 mg/kg/day p.o. from
day 15 of gestation, showed dystocia and
increased pup mortality.
In children - The conditions for safe and
effective use in children under 12 years
of age have not been established and the
drug is therefore not recommended in
this age group.
PRECAUTIONS: Use with caution in
patients with a history of gastrointestinal
inflammatory disorders or ulceration.
Orudis tablets, capsules and suppositories can cause upper gastrointestinal
toxicity, including hemorrhage.
Suppositories should be given with caution to patients with any rectal or anal
pathology.
The drug should be given under close
medical supervision in patients with
impaired liver or kidney functions.
Orudis may mask signs of infectious diseases. This should be kept in mind so that
any delay in diagnosing and treating
infection may be avoided.
Use In patients taking oral antIcoagulants: Orudis has been shown to
depress platelet aggregation in animals.
However, in twenty patients undergoing
therapy with coumarin, Orudis failed to
demonstrate potentiation of anticoagulant effect. Nevertheless, caution is
recommended when Orudis is given
concomitantly with anticoagulants.
The presence of Orudis and its metabolites in urine has been shown to interfere
with certain tests which are used to detect
albumin, bile salts, 1 7-ketosteroids or 17hydroxycorticosteroids in urine and which
rely upon acid precipitation as an end
point or upon color reactions of carbonyl
groups. No interference was seen in the
tests for proteinuria using Albustix, HemaCombistix or Labstix Reagent Strips.
ADVERSE REACTIONS: GastroIntestinal: they were the most frequently
observed and were seen in approximately
22% of patients. Ulceration and gastrointestinal bleeding have been noted in a
few patients (approximately 0.8%). Other
adverse reactions in order of decreasing
frequency were: gastrointestinal pain,
nausea, constipation, vomiting, dyspepsia
and flatulence, diarrhea, anorexia and
bad taste in mouth. Rectal administration
was associated with a lower incidence of
upper gastrointestinal reactions (12%)
with the exception of ulceration, the incidence of which was the same.
However, anorectal reactions presenting
as local pain, burning, pruritus, tenesmus
and rare instances of rectal bleeding
occurred in 16.5% of subjects. 5% of patients discontinued rectal therapy because

of these local reactions. Central Nervous

System: headache, fatigue, dizziness,
tension, anxiety, depression and drowsiness. Skin: rashes, pruritus, flushing,
excessive perspiration and loss of hair.
Allergic: urticaria, angioedema and
asthma. Cardlovascular: mild peripheral
edema, palpitation and bruising. Auditory
system: tinnitus. Mouth: ulcers, sore
tongue, inflammation of the mouth and
gums.
Laboratory Tests: Abnormal alkaline
phosphatase, lactic dehydrogenase,
glutamic oxaloacetic transaminase and
blood urea nitrogen values were found in
some patients receiving Orudis therapy.
The abnormalities did not lead to discontinuation of treatment and, in some cases,
returned to normal while the drug was
continued. There have been sporadic
reports of decreased hematocrit and
hemoglobin values without progressive
deterioration on prolonged administration
of the drug.
SYMPTOMS AND TREATMENT OF
OVERDOSAGE: Symptoms: At this time,
no overdosage has been reported. Treatment: Administer gastric lavage or an
emetic and treat symptomatically: compensate for dehydration, monitor urinary
excretion and correct acidosis if present.
DOSAGE AND ADMINISTRATION:
Adults: Oral: The usual dosage for
enteric-coated tablets or capsules is 150
to 200 mg per day in 3 or 4 divided
doses.
Orudis-E tablets provide an alternative
presentation for those who may prefer this
dosage form. No difference in toxicity
profile was documented.
Rectal: Orudis suppositories offer an
alternative route of administration for
those patients who prefer it. Administer
one suppository morning and evening or
one suppository at bedtime supplemented as needed by divided oral doses. The
total daily dose of Orudis (capsules,
tablets and suppositories) should not
exceed 200 mg.
When the patient's response warrants
it, the dose may be decreased to the
minimum effective level. In severe cases,
during a flare-up of rheumatic activity
or if a satisfactory response cannot be
obtained with the lower dose, a daily dosage in excess of 200 mg may be used.
However, a dose of 300 mg per day
should not be exceeded.
Children: Orudis is not indicated in
children under 12 years of age because
clinical experience in this group of
patients is insufficient.
Availability: Capsules of 50 mg, bottles
of 100 and 500.
Tablets (enteric-coated) of 50 mg, bottles
of 100 and 500.
Suppositories of 100 mg, boxes of 30.
Store below 30C.
Product information as of Jan. 7, 1983.
Product Monograph available on request.

References

MOiller-Fassbender, H., et al., XV Int. Congr.

Rheumatol., Paris, 1981
2. Willans, M.J., et al., Curr. Ther. Res., 25, 1, 35, 1979
3. Mitchell, W.S., et al., Curr. Med. Res. Opin.,
3, 423, 1975
4. Howard, D.L.G., Curr. Ther. Res., 23, 6, 678,1978
5. Russel, A.S., et al., Curr. Ther. Res., 33, 2, 1983
6. Gomez, G., Proceedings, Vil Eur.
Rheumatol. Congr., Helsinki, June 1975
7. Fujimori, I., et al., Shin Ryo to Shin'Yaki, 11, 101, 1974
8. Willans, M.J., et al., Curr. Ther. Res., 31, 6, 913, 1982
9. Fava, G., et al., J. Int. Med. Res., 5, 301, 1977
10. Quenneau, P., et al., Proceedings (Supp.),
VIli Eur. Rheumatol. Congr., Helsinki, 1975
1.

Rh6ne-Poulenc Pharma Inc.

-POULENC 8580 Esplanade
Montreal, Ouebec FIpAA-I

61 Authorized user

2172

LLLPI

Cowdry's the care of the geriatric patient

Critical issues in family practice ........... 85

Current medical diagnosis and
treatment ....................... ..... 154
Current obstetric and gynecologic
diagnosis and treatment .................. 128
Current pediatric diagnosis and treatment
27

Cyriax J

.............................

Danto J. L. ......................... ....

Davis-Christopher textbook of surgery ...
DeGowin E. L. .............................
DeGowin R. L .............................
De Palma's the management of fractures
and dislocations: an atlas ................
Dermatology: diagnosis and treatment of
cutaneous disorders .......................
(The) development of the infant and
young child .............................
DeWeese D. D. .............................
Diagnosis and treatment of alcoholism for
the primary care physician ...............
Diekelmann N. L ...........................
Diet manual .............................
Differential diagnosis and treatment in
social work .............................
Dineen J. J .
(The) doctor and his patient ................
(The) doctor and the law ....................
(The) doctor, his patient and the illness ..
Doctor-patient communication .............
(The) doctor-patient relationship ..........
Doctors talking to patients ..................
Doherty W. J .............................
Domonkos A. N .............................
Dorland's illustrated medical dictionary ..
..............
Do'yle D. ........
Driesbach R. H. ................. .....
Dripps R.D.
Dubovsky S. L ...................... 175,
(The) dying patient ......................
.

.............................

......................

Early care of the injured patient ...........

Eastham R. D .
Eisenberg L. ..........
............
Ellis H. .............
...............
Emergency medicine: concepts and
clinical practice ...........................
EmsonH.E
......
Enelow A. J .
Environmental and occupational
medicine ......................
Erikson E. H .
Essentials of geriatric medicine ............
Ethical decisions in medicine ..............
(The) extra pharmacopoeia .................
......................

............................

......................

Fabb W. E .
Faculty development through

......................

141

36
196
39
39

139

36
101
145
179
52
125
191
61
192
114
48
47

46
50
71
37

212
95
62
15
182
97

64
11
193
10

60
114
45
132
98
I
67
157

55, 56

53
workshops ......................
Family Medicine Literature Index
203
.............
(FAMLI) .........
Family Medicine: The medical life history
74
of families .............................
Family medicine: principles and
87
application .............................
79
Family medicine: principles and practice
Family medicine research: a current
Canadian index ............................ 208
Family nursing: theory and assessment ... 121
Family practice: foundation of changing
77
health care .............................
Family practice manual ............... 168
Family therapy and family medicine .............. 71
Fanaroff A.A. ...............28
Peinbloom R.I. ...............41
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

Fletcher R. H. ............................
185
Fletcher S. W. ............................
185
Flint's emergency treatment and
management ............................
59
Focus on learning in family practice ...... 55
Foote W. R. ........................... . 129
(A) fortunate man ............................ 19
Fowler G .
170
99
Fraiberg S. H .
Freedman G. R ............................ 72
46
Freeling P .
Freeman A. M. ............................ 176
Freeman R. B .
117
Freidman M. M. ........................... 121
Friedman G. D. ........................... 186
Prisse M. ..............
.............
153
Fry J ............................ 76, 82
Fundamentals of family medicine ......... 80
Fundamentals of geriatric medicine .......
3
Future general practitioner: learning and
57
teaching ...........................
............................

...........................

............................

..........................

Ganong W. F. ...........................
162
Gehlbach S. H .
190
General ophthalmology ..................... 136
General urology ........................... 199
91
Genetics in medicine ........................
Geriatric medicine for students ............
2
Geyman J. P ................. 77, 83, 84, 187
Gilman A. G. ......
152
...........
Glass
R.H ................. 126
137
...........
Glasspool M. ......
Goodhart R. S. .......
122
..........
152
Goodman L. S
..................
GorollA.H ................. 106
12
Grant's atlas of anatomy .................
Grant's method of anatomy ................
13
14
Gray's anatomy ........
.........
Gray D.J ................. 210
170
Gray M. .....
............
Green M. .....
24
............
100
..................
Greydanus D. E
Griffith H. W. .......
150
..........
Growth and development of children
103
(A) guide to immunization for Canadians
31
Guyton A. C. .............................
163
Haddad L. ...................... ....... 63
Haggerty R. J ............................. 24
Handbook of nonprescription drugs .......
156
Handbook of poisoning: prevention,
diagnosis and treatment .................. 62
2
Hanley T. ...................... .......
Harris C. M. .............................
46
Harrison's principles of internal
108
medicine .............................
Hart C. R .
25
Harvey A. M. ............................. 107
Hasler J. ................. ............ 47
Health maintenance guide .................. 172
Health promotion in nursing practice
120
Health promotion: principles and clinical
applications ............................. 174
(A) health sciences library basic
manual .............................
209
Heaton C. L .
34
Heffernan M. W ............................. 55
Heinrich J. ........................ ..... 117
Hennen B. K .
88
Herr J. J. ................... ..........
8
42
Hodgkin K. .............................
Hoffman J. ......................... .... 23
Hofmann A. D. ............................. 100
How to write and publish papers in the
medical sciences.201
Howie J. G. .............................
188
Human labor and birth ...................... 129
..........................

.............................

............................

............................

Hume D.

....................

.........

197

CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984

HuthE.J

Huygen F.

.........

.........

201
74

207
ICHPPC-2 .........
......... 26, 101
Illingworth R. S
Illustrated Stedman's medical dictionary . 213
150
Instruction for patients ......................
(The) intellectual basis of family
practice .................. .......... 89
Interpretation of diagnostic tests ........... 112
Interviewing: a guide for health
44
professionals ............................
Interviewing and patient care ........... ... 45
Interpreting the medical literature ......... 190
Introduction to anesthesia ................... 15
(An) introduction to family medicine ..... 86
(An) introduction to medical genetics .... 90

Johns R. J. .................. .......... 107

Judge R. D. ...................... ...... 40
Juhl J. H . ............... ............. 184
Kaplan H. I .

...........................

Kelly J. B .

............................

177
75
27
28
193
52
178
73
159
154

Kempe C. H. ............................
Klaus M. H.
Kleinman A.
Knopke H. J. ............................
Kolb L. C. .................. ..........
Kolodny R. C .
Kottke F. J. ...................... ......
Krupp M. A. ............................
Krusen's handbook of physical medicine
and rehabilitation .......................... 159
Kubler-Ross E ............................ 92, 93
85
Kushner K. P. ............................
............................

............................

...........................

Lancaster J. ....................... .....

Last J. M .
Lawson J. G. ............................
Ledingham J. G. ............................
Lehmann J. F. ............................
Levy B. S. ................... .........
Lewis A. J .
Lidz T .............................
(The) life cycle completed: a review ......
Living with death and dying .......... .....
Long B. E.
Long-term prescribing .......................
Low back pain syndrome ...................
Lowrey G. H .
............................

............................

............................

............................

118
171
165
109
159
131
65
102
98
93
50
158
144
103

43
38
MacDonald P. C ............................. 130
99
Magic years .............................
Maher G. .................. ........... 68
(The) management of terminal disease ... 96
Manual for authors and editors ......... ... 200
Manual for the College office record ..... 169
(A) manual of dermatology ............ ..... 34
Manual of medical therapeutics ......... ... 153
Manual of skin diseases ..................... 35
Marinker M. ............................ 51, 81
56
Marshall J. R. ............................
Marshall T. D. ............................ 115
Martindale W. A ............................ 157
Masters W. H .
73
Maxcy-Rosenau public health and
preventive medicine ...................... 171
106
May L.A.
McCaffery M. ............................ 202
McConnell J. W ............................ 165
166
McCue J. D. ............................
McIntyre K. M.
.65
McKeown T. .............................
20
McKusick V. A. ............................. 107
McLean S. ......................... .... 68
MacAdam D. B.

.............................

MacBryde's signs and symptoms ........

...

...........................

............................

McPherson A ............................. 127

McWhinney I. R. ............................
86
Medalie J. H. .............................
87
(The) medical annual 1984 ................. 210
Medical choices, medical chances ........ 41
Medical subject headings (MeSH) 1984 .. 206
Medicine, morals and the law .............. 68
Modern clinical psychiatry ................. 178
Modern nutrition in health and disease ... 122
Modern synopsis of comprehensive
textbook of psychiatry III ................
177
Mohr J. .......
...............
19
Moncure A. C. .............. ........ 61
Moore D. C. ..........
............
16
Morrell D ....................... 51, 81
Mulley A. G. ...........
106
...........
Murray R. B . ...........
...........
119
National Advisory Committee on
Immunization ................. .....
National Library of Medicine .. 203, 205,
(The) nature of general family practice ...
Nelson textbook of pediatrics ..............
New readings for general practitioners ...
Newell F. W. ...........
...........
Nursing assessment and health promotion
through the life span ....................
Nutritional support of medical practice ...

O'Brien D.....................................
Occupational health: recognizing and
preventing work-related diseases .......
O'Donoghue D. H...........................
Office gynecology ...........................
Office practice of medicine .................
On death and dying ..........................
Ontario Dietetic Association, Ontario
Hospital Association ......................
Ontario Medical Association ...............
Ophthalmology: principles and concepts

31
206
56
22
204
135
119
123
27
131
195
126
105
92

125
209
135
142

Orthopaedics in primary care ..............

Outline of fractures, including joint
injuries ...................................... 138
Outline of orthopaedics ..................... 140

Oxford textbook of medicine ............... 109

Oxorn H....................................... 129
Palliative care: the management of
far-advanced illness .......................
Parkes C. M..................................
Patterns of Practice and Health Care
Delivery Committee, The College of
Family Physicians of Canada ...........
Patterson R....................................
Paul and Juhl's essentials of roentgen

95
94
172
9

184
23
Penibrey M. E................................ 90
Pender N. J................................... 120
Pendleton D................................... 47
Petersdorf R. G............................... 108
Periodic health examination ................ 173
The person: his and her development
throughout the life cycle ................. 102
Phillips W. A................................. 55
(The) physician and Canadian law ........ 115
(The) physician as manager ................ 164
Physical medicine and rehabilitation ...... 161
Pillsbury D. M............................... 34
Practice: a handbook of primary medical
81
care ..........................................
148
Practical approaches to patient teaching
170
Preventive medicine in general practice
Primary care .................................. 76
Primer of epidemiology ..................... 186
Primer on the rheumatic diseases .......... 17
Principles of ambulatory medicine ........ 104

interpretation

...............................

Pediatrics ......................................

2173

Bactrim Roche
Rx Summary
Indications
The following infections when caused by susceptible
pathogens:
O upper and lower respiratory tract (particularly chronic
bronchitis and including acute and chronic otitis medial
D7 urinary tract: acute, recurrent and chronic
El genital tract: uncomplicated gonococcal urethritis
C: gastrointestinal tract
O7 skin and soft tissue
C: Pneumocystis carinii pneumonitis in infants
and children.
Not indicated in infections due to Pseudomonas,
Mycoplasma or viruses.
Contraindications
Evidence of marked liver damage or renal impairment where
repeated serum assays cannot be carried out; blood
dyscrasias; known hypersensitivity to trimethoprim
or sulfonamides.
During pregnancy, and in newborn or premature infants
during first few weeks of life.
Precautions
Benefit should be critically appraised against risk in patients
with liver damage, renal damage, urinary obstruction, blood
dyscrasias, allergies, or bronchial asthma. Reduce dosage
in patients with renal impairment. Do not administer if
serum creatinine level is above 2 mg%. Consider possible
superinfection with a non-sensitive organism.
Adverse reactions
Most frequent: nausea, vomiting, gastric intolerance,
and rash.
Less frequent: diarrhea, constipation, flatulence, anorexia,
pyrosis, gastritis, gastroenteritis, urticaria, headache, and
liver changes (abnormal elevations in alkaline phosphatase
and serum transaminase).
Occasionally reported: glossitis, oliguria, hematuria, tremor,
vertigo, alopecia, and elevated BUN, NPN, and serum
creatinine.
Hematological changes: primarily, neutropenia and
thrombocytopenia, and less frequently, leukopenia, aplastic
or hemolytic anemia, purpura, agranulocytosis, and bone
marrow depression; occur particularly in the elderly
and mostly prove reversible on withdrawal.
Dosage
Children: 6 mg trimethoprim/kg body weight per day,
plus 30 mg sulfamethoxazole/kg body weight per day,
divided into two equal doses.
Adults and children over 12 years of age:
Standard dosage:
1 'Bactrim' DS 'Roche' tablet or 2 adult tablets, twice daily.
Minimum dosage and dosage for long-term treatment:
1/2 'Bactrim' DS 'Roche' tablet or 1 adult tablet,
twice daily.
Maximum dosage (overwhelming infections):
1 1/2 'Bactrim' DS 'Roche' tablets or 3 adult tablets,
twice daily.
In acute infections treat for at least 5 days or until patient is
asymptomatic for 48 hours; in urinary tract infections, until
urine sterile.
Uncomplicated gonorrhea: 2 adult tablets or 1 'Bactrim' DS
'Roche' tablet four times daily for 2 days.
Pneumocystis carinii pneumonitis: 20 mg/kg/day
trimethoprim and 100 mg/kg/day sulfamethoxazole in four
divided doses for 14 days.

Supply

Adult tablets: White, capsule-shaped, biconvex tablet

with ROCHE C engraved on one face and BACTRIM and
indented score on the other, each containing 80 mg
trimethoprim and 400 mg sulfamethoxazole.
Bottles of 100 and 500. Unit dose, boxes of 100.
DS tablets: White, capsule-shaped, biconvex tablet
with ROCHE engraved on one face and BACTRIM DS and
indented score on the other, each containing 160 mg
trimethoprim and 800 mg sulfamethoxazole.
Bottles of 100 and 250.
Suspension: Cherry flavoured, 40 mg trimethoprim
and 200 mg sulfamethoxazole per 5 mL.
Bottles of 100 and 400 mL.
Pediatric tablets:
White, cylindrical biplane tablet with
engraved on one face, single scored on the other with C
above and below score line, each containing 20 mg
trimethoprim and 100 mg sulfamethoxazole.
Bottles of 100.
Solution for Infusion: 5 mL amber-coloured ampoules,
containing 80 mg trimethoprim (16 mg/mL) and 400 mg
sulfamethoxazole (80 mg/mL) for infusion with D5W,
Ringer's solution or NaCI 0.9% solution. Packs of
25 ampoules.
PAAB
Product monograph availab,le on request.
TM: Trade Mark of Hoffmann-La Roche Limited
CCP
Reg. Trade Mark
4060
Copyright 1984
References:
1. Bottone E et al. Evaluation of the clinical efficacy of
erythromycin, amoxicillin and co-trimoxazole in the
treatment of acute respiratory tract infections in paediatric
patients. Curr Med Res Opin 1982;8(2):67-74.
2. Cooper J et al. A Comparison between co-trimoxazole
and amoxicillin in the treatment of acute otitis media in
general practice. Practitioner 1976;217:804409.
'Bactrim' 'Roche' is listed in provincial formularies.

/ws
~~Hoffmann-La Roche Limited
/<b Etobicoke, Ontario M9C 5J4

Original Research in Medicine and Chemistry

(The) principles and practice of medicine

Primary care medicine ......................
Principles of surgery .........................
Pritchard J. A . .............................
Private practice: surviving the first
year .............................
Problems in ophthalmology .................
(The) process of patient teaching in

nursing .............................

107
106
197
130

166
137
149
66

Professional ethics ...........................

Psychiatry for the primary care
physician .............................
Psychology and medicine:
psychobiological dimensions of health
and illness .............................
Psychotherapeutics in primary care .......

181
182

Quick reference to the diagnostic criteria

from DSM-Ill .............................

180

176

Stanhope M.

118

..............................

Starting and managing your practice-a

guidebook for physicians ........... .....
Statistics in medicine ........................
Steinberg F. U ..............................
Stephens G. G ..............................
Stewart W. D. ..............................
Stillwell G. K .............................
Strength in study .............................
(The) stress of life ...........................
Surviving the breakup: how children and
parents cope with divorce ........... .....
Swisher S. N ..............................
Synopsis of oral pathology ............ .....
Synopsis of pathology .......................
Task force on the periodic health
examination ..............................
79, 80,
Taylor R. B .
Talking with patients ........................
Teaching general practice ............. ......
Textbook of advanced cardiac life
support ..............................
Textbook of disorders and injuries of the
musculoskeletal system ............ ......
Textbook of emergency medicine .........
Textbook of family practice ........... .....
Textbook of medical physiology ..........
Textbook of orthopaedic medicine ........
Textbook of otolaryngology ........... .....
Textbook of sexual medicine .......... .....
Thompson J. S . ..............................
Thompson M. W. ............................
Tinker R. V. ..............................
To comfort always: caring for the older
patient-a challenge for family
physicians ..............................
Top F. H.
Towards earlier diagnosis in primary care
Treatment of injuries to athletes ...........
Turner F. J . ..............................
...................

Rakel R. E. ........... ..... 78, 155,

Ramamurti C. P .............................
Ravel R .
Recommended nutrient intakes for
Canadians .............................
Redman B. K. .............................
Regional block: a handbook for use in the
clinical practice of medicine and
surgery .............................
Rehabilitation medicine .....................
Reichel W.
(The) relevance of social science for
medicine ........................ .....
Report of the Committee on Infectious
Diseases ........................ .....
Research in family practice ............ .....
Research in general practice ........... .....
Review of medical physiology ......... ....
Robbins S. L .
Roberts J. A. .............................
Rodnan G. P. .............................
(The) role of medicine-dream, mirage or
.............................

.............................

............................

211
142
113
124
149
16
160
4

193
29
187
188
162
147
90
17

20
nemesis? .............................
Rom W. N.
132
Rosen P. ................. ............ 60
Rossman I. .....
........... 3, 5
Royal College of General
Practitioners ........
........ 57, 204
Rozovsky L. E. ............................. 116
Rubin P. .................
134
............
Rudolph A. M ............................. 23
Rusk H. A . ........................ ..... 160
.............................

Sabiston D. C ............................. 196

Sack R. L . .................... ......... 176
177
Sadock B. J. .............................
143
Salter R. B. .............................
Sauer G. C. .............................
35
Saunders C. M ............................. 96
Saunders W. H ............................. 145
Schneider H. A . ............................. 123
17
Schumacher H. R. ...........................
Schwartz S. I. ............................. 197
146
Scotti W. A.
Selected references for teaching and
learning in family medicine ......... .... 58
Selye H. ................. ............ 183
72
Sexual medicine .............................
122
Shils M. E .
Shires D. B .
88
18
(A) short history of medicine .......... ....
27
Silver H. K .
Smith D. R .
199
Smith L. H.
110
Snell R. S. ..............11
Sports medicine in primary care............... 194
Standards for accreditation of Canadian
health care facilities ...............
167
.............................

.............................

.............................

..............................

Vaughan D.

............................

Vaughan V. C

..............................

165
189
6
89
36
159
21
183
75
45
33
146

173
174
49
51

65
143
61
78
163
141
145
73
91
91
142
7
32
42
195
191

136
22

Wagner E. H ..............................
Wallach J. B . ..............................
Wallerstein J. S. .............................
Warrell D. A ..............................
Warwick R ................. ............
Washburn K. B . ..............................
Weakland J. H ..............................
Weatherall D. J ..............................
Wegman D. H. .............................
Wehrle P. F. .............................
Weissberg M. P. .............................
Weston W. W ..............................
Wilkes
E
.... 97,
Wilkins E. W. .............................
Williams obstetrics ..........................
Williams P. L .............................
Winchester J. .............................
Wolcott M. W. .............................
Women's problems in general practice ...
WONCA ........
........... 203,
Woods D . ......
.............
Working with the family in primary care
............
Wright H. J. .......
Writing that's worth reading ...............
Wyngaarden J. B.

185
112
75
109
14
161
8
109
131
32
175
58
158
61
130
14
63
198
127
207
21
70
43
202
110

Year book of family practice ...............

211

...................

.............................

.............................

Zentner J. P.
..........119
Zieve P.D. ..........104
Zuidema G. D ...............40
CAN. FAM. PHYSICIAN Vol. 30: OCTOBER 1984