Professional Documents
Culture Documents
FACULTY OF MEDICINE
GADJAH MADA UNIVERSITY
YOGYAKARTA
2013
RESEARCH PROPOSAL
ANALYSIS OF THE TIME BETWEEN ONSET OF
STROKE AND ADMITTANCE TO HOSPITAL FOR
STROKE PATIENT IN DR SARDJITO HOSPITAL
FROM 2009-2013
Submitted by
Material advisor
Date:
Date:
Chapter I. INTRODUCTION
a. Background:
Stroke occurs when the blood supply to the
brain is blocked or when a blood vessel in the
brain ruptures, causing brain tissue to die. It is
defined
as
neurological
sudden,
non
function
due
convulsive
to
an
loss
of
ischemic
or
2003).
It
can
be
classifie
into
major
form
of
stroke on
of
supplying
an
the
other
obstruction
blood
to
the
hand
of
brain
occurs
as
blood
vessel
causing
tissue
Transient
Ischemic
Attack(TIA)
which
10.6%
of
deaths
worldwide
in
2011
are
alone,
cause
death
of
stroke
among
has
adult
become
the
contributing
leading
up
to
Symptoms
of
strokes
arise
due
to
the
speaking
or
understanding
others,
DHDSP,
strokes
2008).
are
Some
of
lasting
the
brain
complication
damage,
of
long-term
onset.
Early
time
of
admission
after
after
the
onset
and
receive
surviving
with
little
or
no
disabilities
longer
by
time
European
to
admission.
Stroke
Meanwhile,
Organization
also
c. Research authenticity:
There
are
several
studies
that
already
Adelaide
Australia
Hospital
between
the
Stroke
year
Unit,
2000
and
South
2002
between
the
year
2009-2013
to
see
Hospital
improvement
in
the
and
to
yearly
see
is
trend
e. Research benefits:
there
of
time
any
to
and
the
doctors
to
formulate
the
f. Ethical clearance:
This
study
will
be
conducted
with
the
ethical
dan
Kesehatan
Fakultas
Kedokteran,
a. Literature review:
a.i.Definition of stroke
Stroke is a sudden focal neurologic syndrome,
specifically
the
type
caused
by
cerebrovascular
disease
pathological
arteries)
that
disorder
or
occurs
of
blood
secondary
blood
vessels
supply
is
to
(usually
defined
as
or
embolus,
blood.
and
There
disease
of
vessel
disturbance
are
two
of
types
wall,
normal
of
thrombus
or
properties
of
stroke
which
are
obstructions
of
big
cervical
caused
by
local
disease
such
as
chronic
b) Hemorrhagic stroke
Hemorraghic
stroke
occur
due
to
spontaneous
c) Subarachnoid hemorrhage
Subarachnoid
hemorrhage
occur
when
there
are
at
the
inferior
surface
of
brain.
Some
glucose
artery
supply
(45%)
unknown
to
embolic
causes
are
the
in
the
brain.
origin
causes
Small
(20%)
of
or
large
and
others
ischemic
stroke
injury
vessel,
thrombosis
in
extracranial
and
at
the
site
of
plague,
thrombus
is
of
collateral
circulation
is
maintained.
Canada
and
Europe
as
benchmark
for
the
began
of
the
last
time
where
the
patient
was
seen
normal.
b.theoritical framework
ischemic
subarachnoid
hemorrhagic
hemorrhagic
stroke
roughened of
endothelial
Increase
intracranial
pressure damages
the brain tissue
forming of
plague
Formation of blood
clot in the brain
forming of
thrombosis
intracerebral
hemorrhage
adherence of
platelet
activated of
coagulation
developing of
thrombus
bursting of brain
blood vessels
hypertension,
coagulation
disorder, vascular
malformation
C.Conceptual framework:
< 90 minutes
< 3 hours
> 3 hours
research
will
use
the
observational
b.Sample size:
The
sample
size
include
all
patients
who
c.Subject:
The
data
collection
will
take
place
in
Dr.
with
intracerebral
thrombotic
hemorrhage
and
of
embolic
any
cause
(4)
primary
(5)
medical
Dr.
f.Research framework:
Identify medical record of patients with first event of
stroke from January 2009 to December 2013
Data collection
Data input
Data analyse
g.Variable:
Independent variable:
Dependent variable
patient
with
first
event
of
stroke
h.Operational definition:
16 until 90
Type of stroke: type of stroke that will be
analyzed are ischemic stroke and hemorrhagic
stroke.
Subarachnoid is not included because it falls
under the population that is not covered in
the guideline by National Institute of Health
and Care Excellent (NICE) (National Institute
of Health and Care Excellent,2013).
i.Result analysis:
The collected data will be put in the table by
using the Microsoft excel. The transferred data is
then will be analyzed.
Time to admission
Percentage
Mean
varia
bles
2009
< 3 hours
> 3 hours
2010
2011
2012
2013
http://publications.nice.org.uk/strokecg68/guidance
10. World Health Organization(WHO), Fact Sheets: Top
10 Leading Cause Of Death In The World 200-2011,
July 2013,
http://who.int/mediacentre/factsheets/fs310/en/ind
ex.html