Professional Documents
Culture Documents
A. Insomnia Disorder
(formerly primary
primary insomnia
insomnia))
Difficulty
>3 mos.
Etiology:
Insomnia Treatment
Behavioral Methods focus on improving
sleep hygiene:
a. Stimulus Control Technique
Make
b. Benzodiazepine
Benzodiazepine-like
like drugs (e.g.,
(e g zolpidem)
usually have fewer side effects.
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B. Hypersomnolence Disorder
(formerly Primary
Primary Hypersomnia
Hypersomnia))
Excessive
Features
Average sleep episode = 9.5 hrs
Normal PSG
Unknown etiology
Exclude other causes before diagnosing
Treatment:
T t
t
Stimulants
Sti
l t (e.g.,
(
methylphenidate)
th l h id t ) to
t
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promote wakefulness.
C. Narcolepsy
Narcolepsy (cont.)
a) Cataplexy
Sudden loss of muscle tone while awake
Sudden
Typically precipitated by emotion
Considered an aberrant manifestation of REM
Considered
sleep
Note: Other REM-related behaviors may be
present but are NOT diagnostic criteria:
sleep paralysis
hypnagogic
yp g g ((upon
p fallingg asleep)
p) hallucinations
hypnopompic (upon awakening) hallucinations
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Narcolepsy
p y ((cont.))
b) Hypocretin deficiency (spinal tap needed)
Hypothalamic neuropeptide
Hypothalamic
Deficiency may be autoimmune-related
c) Characteristic PSG abnormalities
(either of the following)
REM sleep latency on a nocturnal PSG.
Narcolepsy
p y Treatment
Polytherapy
1) Stimulants
Sti l t for
f somnolence
l
(
(e.g.,
modafinil)
d fi il)
and
2) Antidepressants for cataplexy
Monotherapy
M
h
D. Breathing-Related
D
Breathing Related Sleep Disorder
Excessive sleepiness or insomnia that is
due to a sleep-related
sleep related breathing condition:
1 Obstructive Sleep Apnea Hypopnea
1.
2 Central Sleep Apnea
2.
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episodes of breathing
cessation/reduction occur per night due to
an upper airway obstruction.
Obstruction
OSAH (cont.)
Apneas/hypopneas
Profile:
f
Middle-aged,
g overweight
g male
who snores loudly and intermittently.
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OSAH Treatment
Continuous Positive Airway Pressure
(CPAP): A device that maintains an open
airway by delivering compressed air at a specific
air pressure to the masks nasal pillow.
Additional
CSA (cont.)
(cont )
A PSG
CRSWD Treatment
Phototherapy at strategic times during the day
to adjust the timing of the sleep-wake cycle.
cycle
Setting
g of Circadian Clock
(governed by the suprachiasmatic nucleus [SCN])
F. Parasomnias
Disorders characterized by abnormal
behaviors associated with sleep.
1. Non-REM Sleep Arousal Disorder
2 Nightmare Disorder
2.
3. REM Sleep Behavior Disorder
4 Restless Legs Syndrome
4.
5. Periodic Limb Movements
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Subtypes
Sleep Walking Type
Sleep Terror Type
Characterized by
episodes
2. Nightmare Disorder
Extremely dysphoric dreams that typically
involve threats to survival, security or physical
integrity.
integrity
Characterized
by
awakening in the 2nd half of sleep period
(during REM sleep)
rapid alertness upon awakening
dream
dream content is well remembered
good recall of the awakening the next morning
Treatment:
RSBD Features
Typically action-filled, violent dreams
Immediately awake, oriented and alert with
detailed dream recall Video
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RSBD (cont.)
(
)
Most common in males >50 years old
Course is progressive and associated with
neurodegenerative
g
disease ((e.g.,
g , Parkinsons
disease, Lewy body dementia)
Treatment
Clonazepam (a benzodiazepine) the
therapeutic
h
i mechanism
h i off action
i iis unclear.
l
Modification
M difi i off sleep
l
environment
i
for
f safety
f
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