Professional Documents
Culture Documents
Youmaywanttostartyourpaperbychoosingaspecificbacterium,Archean,orvirus
andsubsequentlyfocustosomethingyoufindparticularlyinterestingaboutthat
organism.Alternatively,youmaywanttochooseacurrentissueorproblemin
microbiologyandfocusontheproblem,coveringtherelevantorganismfromthat
perspective.However,itisabsolutelyrequiredthatyoudiscussthepertinentbiology
oftheorganismsyouarestudyinginyourpaper.
Pleasetalktotheinstructorsandwecanprovideyouwithmorespecificsonthetopics
listedbelow.Pleasedonotfeelconstrainedbythesesuggestions.Followyourown
creativeidea!
Recentdiscoveries
Fluvaccineshortages
Bacteriawithcytoskeletons/evolutionarytree
Biofilmformationindisease,theenvironment,orindustry
Quorumsensing:howbacteriacommunicate
Developmentinprokaryotesspore
formation,Caulobacter,Myxococcus,Streptomyces
Lifeinextremeenvironments
Extraterrestriallife
Biodegradationofanthropogeniccompounds(PCB's,dioxinspesticides,etc.)
bybacteria
Evolutionoflife
Antibiotic/antiviralresistancemechanisms
Howtopreventantibioticresistance
Antibacterialproducts
Symbioticrelationshipsbetweenbacteriaandotherorganisms
Viable,butnonculturableorganisms
Antibacterialeffectsofspices
Emerginginfectiousdiseases
Avianflu
SARS
IncreaseinhepatitisC
Madcowdisease(BSE)
Norwalkvirusesandcruiseshipoutbreaks
Bioterrorism
Pathogenesisofagentsofconcernanthrax,smallpox,etc.
Preparednessresponsevaccines,antibioticstockpiling,drills
Pathogensandlinkstochronicdisease
Helicobacterpyloriandulcers
Chlamydiapneumoniaeandheartdisease
Chlamydiaandinfertility
Crohnsdisease
GuillianBarresyndrome
Pathogensandlinkstomalignancy
HumanherpesvirusandKaposisarcoma
Papillomavirusandcervicalcancer
HumanTcellleukemiavirusandleukemia
EpsteinBarrvirusandlymphoproloferativedisorders
Pathogenesis(manybacteriaandvirusescanbeexaminedinthiscontext)
Biotechnology
NovelpharmaceuticalproductsfrombacteriaorArchaeafromextreme
environments.
Genetherapyusingviralvectors
Level4labs
Foodirradiation
UseofPCRandDNAfingerprintingforcharacterizationofbacterial
communitiesinsoil,biofilmsorhostenvironments.
ProductionorbiodegradationofPHVB's(i.e.,biodegradableplastics)by
bacteria.
Epidemiology
Identifyingandfollowinganoutbreak
Trackingfoodbornepathogens
Molecularmethodsforidentifyingmicrobes
Bacteriaandyourbody
Useofbotulinumtoxinforcosmeticpurposes
Acneandbacteria
Normalmicrobiotaandpreventionofdisease
Flatulence,intestinalbacteria,andprobiotics
Cell Biology
David Andes, Andes Lab website
Medical Microbiology & Immunology: Antifungal activity and drug resistance
Briana Burton, Burton Lab website
Bacteriology: Molecular mechanisms of macromolecule transport across membranes.
Silvia Cavagnero, Cavagnero Lab website
Chemistry: Mechanisms of protein folding in the cell. Chaperone- and ribosome-assisted prevention of aggregation.
The effect of antibiotics on cotranslational protein folding.
Paul Friesen, Friesen Lab website
Biochemistry (Virology): Molecular biology of eukaryotic DNA viruses regulation of gene expression programmed cell
death (apoptosis) and retrotransposons.
Jenny Gumperz, Gumperz Lab website
Medical Microbiology & Immunology: Molecular and functional analyses of T lymphocytes in innate immunity
Anna Huttenlocher, Huttenlocher Lab website
Medicine/Medical Microbiology and Immunology: Molecular mechanisms of leukocyte chemotaxis and inflammation
Robert Kalejta, Kalejta Lab website
Molecular Virology: Viral modulation of the cell cycle
Laura Kiessling, Kiessling Lab website
Biochemistry: Molecular mechanisms underlying bacterial sensing and mycobacterial cell wall biosynthesis.
Laurence Loewe, Loewe Lab website
Genetics, WID: Evolution, systems biology, population genetics, evosysbio in diverse systems, all investigated by
computer simulations.
Megan McClean, McClean Lab website
Biomedical Engineering: Microfluidic and optogenetic tools for studying microbial signal processing
Nathan Sherer, Sherer Lab website
Molecular Virology, Oncology: HIV-1 RNA trafficking, virus-Host interactions
M. Suresh, Suresh Lab website
Pathobiological Sciences: Regulation of T cell proliferation apoptosis and memory
Douglas Weibel, Weibel Lab website
Biochemistry: Biochemical studies of bacterial physiology and behavior
Project is a word that terrifies most of the college students. This is because of the experience they had in
their schools. I remember when I searched a lot for project ideas as my project guide and other
professors werent that supportive. So here are a few innovative Micro biology project ideas to help you
out:
Microalgae
Soil Biology
Diversity and distribution of soil algae
There have been very few investigations of soil algae in New Zealand although they are an important
component of microbial communities in the upper few centimetres of most soils. How diverse are they?
How do communities differ between naturally-occurring and agricultural and other human-impacted soils?
Are New Zealand soil algae very similar to those described from other regions or do some soil types
support unique communities? Do high alpine soils support communities similar to those found in
Antarctica? What controls differences in community structure between different soil types? How
abundant are soil algae? How responsive are they to changes in their microenvironment, e.g. water
availability, temperature, nutrients? A range of taxonomic, ecological and experimental studies could be
designed to suit interests.
Degree: Honours / Masters / PhD
Background/skills required: Basic microbiological skills. Enthusiasm for microscopy and descriptive
studies.
Field/lab support funding is available.
Supervisor: Dr Paul Broady
Virology
The hunt for novel DNA viruses: Diversity and evolution through recombination
Rolling circle amplification using Phi29 DNA polymerase has revolutionised the non-specific amplification
of circular DNA viruses. Techniques established by my research group at the University of Cape Town,
South Africa, will be used to sample for novel DNA viruses in various ecosystems. Initially the project will
focus on the following:
1. Avian DNA viruses, mainly circoviruses and polymoviruses, in archived samples of mallards and
ducks undergoing an evolution bottle neck.
2. Corticoviruses and microviruses infecting bacteria will involve in dept studies on evolution through
recombination, measuring recombination hotspots and evolution rates
3. Plant viruses such as caulimoviruses and begomoviruses.
Degree: Honours / MSc
Background/skills required: Basic molecular biology
Confused on how to start your research work? We are here to help you, you can browse through
numerous projects/dissertations, essays/papers, seminars and reports in microbiology.
October-December 2015
Volume 33 | Issue 4
Page Nos. 473-621
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GUEST EDITORIAL
Paradox of autoantibodies and immune deficiency: Interferon gamma
antibodies and susceptibility to intracellular pathogens
S Sehgal, D Suri
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473
DOI:10.4103/0255-0857.167356 PMID:26470950
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REVIEW ARTICLE
Advantage and limitations of nitrofurantoin in multi-drug resistant Indian
scenario
Laishram Shakti, Balaji Veeraraghavan
DOI:10.4103/0255-0857.167350 PMID:26470951
p.
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SPECIAL ARTICLE
How to develop an in-house real-time quantitative cytomegalovirus
p.
polymerase chain reaction: Insights from a cancer centre in Eastern India 482
Anusha Harishankar, Mammen Chandy, Sanjay Bhattacharya
DOI:10.4103/0255-0857.167351 PMID:26470952
ORIGINAL ARTICLES
Quantification of human polyomavirus JC virus load in urine and blood
samples of healthy tribal populations of North-Eastern part of West
Bengal, India
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Sharma
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BRIEF COMMUNICATIONS
HIV reverse transcriptase gene mutations in anti-retroviral treatment
nave rural people living with HIV/AIDS
K Mohanakrishnan, A Kasthuri, SK Amsavathani, G Sumathi
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DOI:10.4103/0255-0857.167326 PMID:26470965
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DOI:10.4103/0255-0857.167318 PMID:26470967
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CASE REPORTS
An ocular cysticercosis case: Caused by Asian genotype of Taenia
solium
M Sharma, N Beke, S Khurana, HS Bhatti, R Sehgal, N Malla
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DOI:10.4103/0255-0857.167319 PMID:26470970
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DOI:10.4103/0255-0857.167329 PMID:26470971
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DOI:10.4103/0255-0857.167322 PMID:26470972
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DOI:10.4103/0255-0857.167337 PMID:26470973
Oral dirofilariasis
RS Desai, N Pai, AP Nehete, JS Singh
DOI:10.4103/0255-0857.167342 PMID:26470974
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COMMENTARY
Human dirofilariasis: A fast emerging zoonosis in India
SK Ghosh
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PMID:26470975
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CASE REPORTS
Tinea corporis due to Trichophyton violaceum: A report of two cases
C Smriti, S Anuradha, T Kamlesh, K Isampreet, K Nitin
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DOI:10.4103/0255-0857.167334 PMID:26470976
CORRESPONDENCE
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DOI:10.4103/0255-0857.167332 PMID:26470980
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DOI:10.4103/0255-0857.167346 PMID:26470981
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Novel sequence type 435 with plasmid-borne New Delhi metallo-lactamase-1 in Acinetobacter baumannii
M Li, J Liu, X Yu, Y Sun, Y Zhang, C Ma, J Ye, T Zhou
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DOI:10.4103/0255-0857.167340 PMID:26470986
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RESEARCH SNIPPETS
Snippet
P Desikan
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DOI:10.4103/0255-0857.167358 PMID:26470988
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ERRATUM
Erratum: Fluconazole susceptibility of 3056 clinical isolates of candida
species from 2005 to 2009 in a tertiary-care Hospital
DOI:10.4103/0255-0857.167357 PMID:26470989
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