Professional Documents
Culture Documents
Version:
26 March 2015
GLIBENCLAMIDE
2.5 mg OR 5 mg TABLETS
TEVA UK Ref:
Version:
fever
Adults
The starting dose is 5 mg a day, taken during metallic taste in the mouth
weight gain
or straight after breakfast (or the first main
meal of the day). This may then be adjusted by increased appetite
swelling of limbs due to accumulation of
your doctor, to a maximum of 15 mg a day.
water
Elderly and very frail patients
low sodium concentration in the blood (this
The normal adult starting dose should be
can be detected from a blood test).
reduced to 2.5 mg a day.
You may occasionally suffer from a hypo (low
Changing from another anti-diabetic medicine blood-sugar attack) relating to your dosage, diet
The starting dose is 5 mg to 10 mg a day,
and exercise, during which you may feel faint,
depending on your previous dosage. This
sick and have cold sweats or palpitations. Your
may then be increased by your doctor, to a
doctor will advise you what to do when you
maximum of 15 mg a day.
first start your treatment with Glibenclamide.
If you are changing from metformin to
You may become allergic to other
Glibenclamide, your starting dose will be
sulphonamide drugs, such as co-trimoxazole.
2.5 mg a day and then adjusted as the
metformin treatment stops, to a maximum Rarely, blood disorders may occur, which may
of 15 mg a day. You may occasionally be
be characterised by pallor, fever or chills, sore
required to take both types of medication throat, ulcers in your mouth or throat, unusual
at the same time, but your doctor will
bleeding or unexplained bruising.
advise you of this.
Similarly, if you are changing from insulin Reporting of side effects
treatment to Glibenclamide, your starting If you get any side effects, talk to your doctor
dose will be 5 mg a day and then adjusted or pharmacist. This includes any possible side
effects not listed in this leaflet. You can also
as the insulin treatment stops, to a
report side effects directly via the Yellow Card
maximum of 15 mg daily.
Scheme at: www.mhra.gov.uk/yellowcard
Children
By reporting side effects you can help provide
Glibenclamide is not recommended for use
more information on the safety of this medicine.
in children.
62606-Z
160 x 323
26 March 2015