Recovery of EDC for the Process of Di Methyl

Amino Iso Propyl chloride Hydrochloride

Sagar V. Modi1, Prof. B.H.Shah2
1, 2

Chemical Engineering Department, L.D.College of Engineering, Ahmedabad-380015

1

sagar.modi15@yahoo.in, 2hopee_79@hotmail.com

Abstract-The Manufacturing Process of DMIPCHCl (Di Methyl Amino Iso Propylchloride Hydro
chloride) is carried out mainly by addition of
Thionyl Chloride, Di- Methyl Amino 2-Propanal
and Ethylene Di Chloride .This process produces
large quantity of EDC (Ethylene Di-Chloride)
which is valuable Solvent & hazardous flammable
liquid which creates a problem during its
recovery. Exposure to Ethylene Di-Chloride can
cause headache, weakness, vomiting, pain or
irritation of the eyes and skin. The focus of the
study is to modify, intensify and develop an energy
efficient process for recovery of solvent by
condenser design which will benefit the Pharma
manufacturing units in Gujarat.
I.
INTRODUCTION
The pharmaceutical industry relies on the use of large
quantities of organic solvents in a great number of
manufacturing steps including chemical synthesis,
fermentation, extraction, formulation and finishing of
products. Solvents such as acetone, methyl ethyl
ketone and tetra hydro furan are commonly used as
reaction media and for extracting products in the
pharmaceutical, specialty chemicals and fragrance
industries .Other solvents frequently encountered
include hexane, dichloromethane, methanol, ethyl
acetate, toluene, xylene, tri ethylamine, Solvent
disposal costs and VOC emissions control have been
primary concerns in the industry for some time. For
various reasons, there is an increasing interest in
recovering solvents with the direct cost saving being
one of the strongest arguments. In some processes
with intensive solvent use, the cost of the solvent can
be a significant proportion of the overall product cost.
Another compelling reason for recovering solvents is
the increasing environmental legislation against
emissions; such emissions may be as a result of a
process design where solvent recovery was not
incorporated at the outset, or where venting has

occurred as a result of plant problems. Advantages of

recycling solvents include:

Significant reductions in removal and disposal

costs
Reduced inventory and the associated
replacement costs of purchasing new solvents
Quality control over the reclaimed solvent
Substantial reductions in the waste solvent that
leaves your facility and in the liability associated
with that solvent.
II.

PROCESS DESCRIPTION

The Manufacturing Process of DMIPC-HCl (Di

Methyl Amino Iso Propyl chloride Hydro chloride) is
carried out mainly by addition of Thionyl Chloride,
Di- Methyl Amino 2-Propanal and Ethylene Di
Chloride in first stage.
.

Figure 1: route of synthesis for Di Methyl Amino Iso

Propylchloride Hydro chloride

In second Stage Addition of Di Methyl Amino 2Propanol in glass line reactor.

Heating and Cooling is done in third and fourth
stage
Sodium dioxide is removing during first second
and third stage which passes to Scrubbing vessel
to Scrubber.
Route of synthesis for Di Methyl Amino Iso
Propylchloride Hydro chloride is shown in figure
1 process flow diagram of Di Methyl Amino Iso
Propylchloride Hydro chloride is shown in figure
2.

Figure 2: Process flow diagram for Di Methyl Amino Iso

Propylchloride Hydro chloride.

III.

METHODOLOGY

In systems involving heat transfer, a condenser is a

device or unit used to condense a substance from
its gaseous to its liquid state, typically by cooling it.
In so doing, the latent heat is given up by the
substance, and will transfer to the condenser coolant.
Condensers are typically heat exchangers which have
various designs and come in many sizes ranging from
rather small (hand-held) to very large. Larger
condensers are also used in industrial-scale
distillation processes to cool distilled vapor into
liquid distillate. Commonly, the coolant flows
through the tube side and distilled vapor through the
shell side with distillate collecting at or flowing out
the bottom.
Process conditions (stream compositions, flow
rates, temperatures, pressures) must be specified.

Required physical properties over the

temperature and pressure ranges of interest must
be obtained.
The type of heat exchanger to be employed is
chosen.
A preliminary estimate of the size of the
exchanger is made, using a heat transfer
coefficient appropriate to the fluids, the process,
and the equipment.
A first design is chosen, complete in all details
necessary to carry out the design calculations.
The design chosen is now evaluated or rated, as
to its ability to meet the process specifications
with respect to both heat duty and pressure drop.
Based on this result a new configuration is
chosen if necessary and the above step is
repeated. If the first design was inadequate to
meet the required heat load, it is usually
necessary to increase the size of the exchanger,
while still remaining within specified or feasible
limits of pressure drop, tube length, shell
diameter, this will sometimes mean going to
multiple exchanger configurations. If the first
design more than meets heat load requirements
or does not use the entire allowable pressure
drop, a less expensive exchanger can usually be
designed to fulfill process requirements.

The final design should meet process requirements

(within the allowable error limits) at lowest cost.
The lowest cost should include operation and
maintenance costs and credit for ability to meet
long-term process changes as well as installed
(capital) cost. Exchangers should not be selected
entirely on a lowest first cost basis, which frequently
changes takes place in future penalties.
IV. CONCLUSION
Ethylene di chloride is use as a solvent in Process of
Di Methyl Amino Iso Propyl chloride Hydrochloride.
For various reasons, there is an increasing interest in
recovering solvents with the direct cost saving being
one of the strongest arguments. The cost of the
solvent can be a significant proportion of the overall
product cost. Another compelling reason for
recovering solvents is the increasing environmental
legislation against emissions. This paper presents the
design procedure for recovery of Ethylene di chloride
by condenser design.

REFERENCES

Robert, H. Perry & Cecil, H. Chilton, Chemical Engineers

Handbook, 5th Edition, McGraw-Hill Company-1973.
Peters Max S. & Timmerhaus Klaus, Plant Design &
Economics for Chemical Engineers, 3rd Edition, Tata
McGraw-Hill Publications.
Ullmann's encyclopedia of industrial chemistry 7th edition.
Kirk-Othmer encyclopedia of chemical technology, volume
27.

Encyclopedia of chemical processing and design, volume

56,by John McKetta J McKetta & William Aaron
Cunningham.
Chemical engineering series, Introduction to process
engineering and design-S.B.Thakore and B.I.Bhatt
Robert E. Treybal, Mass Transfer Operation , 3rd Edition,
Mcgraw-Hill Publication.