Professional Documents
Culture Documents
Primitive Follicle
Call Exner Body
#5 Ovary LG Serous CA (Serous ovarian CA, ovarian serous adenocarcinoma, papillary serous + psammoma bodies,
serous cystadenocarcinoma low grade with psammoma bodies, papillary serous cystadenocarcinoma gross x 2)
#7 Ovary Benign Serous Cyst (Serous cystadenoma gross x2, benign cystadenoma opened to show multiloculation)
#10 Colon Adeno Cancer (neoplastic glands of adenocarcinoma have crowded nuclei with
hyperchromatism and pleomorphism. No normal goblet cells are seen.)
#13 Complete Mole (grapelike chorionic villi, atypical trophoblastic proliferation, but chorionic villi are still present.
#14 Placenta Percreta with fetus (postop view of uterus showing spontaneous rupture (arrow) due to placenta percreta)
#16 Cervix SCC - fungating red to tan to yellow mass that obscures the cervical os
The glandular and cribriform endometrioid pattern fits with type I endometrial
CA. This neoplasm is superficially invasive into the myometrium at the right.
(micronodular <3mm, commonly caused by chronic alcoholism, yellowish hue due to fatty change, AST>ALT)
(Microscopically, the regenerative nodules of hepatocytes are surrounded by fibrous connective tissue that bridges between portal tracts. Also note
macrovesicular steatosis/fatty change on the left.)
#24 Cecum - Perforated (distal large bowel obstruction, unrelieved cecal volvulus, trauma to the right side of abdomen, or ingested foreign bodies)
#25 Penis SCC (reddish-tan with ulcerated surface, non-circumcision is a risk factor)
#26 Lung Saddle Pulmonary Embolus (usually from large veins of the legs)
#27 Uterus MMMT- carcinosarcoma: Adenocarcinoma (endometrioid, serous, clear cell) mixed with malignant mesenchymal (sarcoma) elements
#29 Uterus Leiomyomata (can be submucosal, intramucosal, subserosal, can be very large, but benign)
#33 Uterus Leiomyosarcoma -more cellular & more pleomorphism and hyperchromatism than benign leiomyoma. Spindle cells + mitoses,
with occasional giant cells seen in sarcomas (including leiomyosarcoma)
#34 Ovary Fibroma (type of ovarian stromal tumor, hard and white)
Staghorn calculus
Pulmonary congestion with dilated capillaries and leakage of blood into alveolar spaces leads to an increase in hemosiderin-laden
macrophages. Brown granules of hemosiderin from break down of RBC's appear in the macrophage cytoplasm. These macrophages are
sometimes called "heart failure cells" because of their association with pulmonary congestion with congestive heart failure.
#45 Breast invasive papillary carcinoma w/ Hematoma (No Utah, also cant find a pic with a hematoma)
Between the bronchial cartilage at the right and the bronchial lumen filled
with mucus at the left is a submucosa widened by smooth muscle hypertrophy, edema,
and inflammation (mainly eosinophils).
#55 Ovary Infarcted tumor (Brenner): Solid to partly cystic epithelial nests surrounded by stroma composed of bundles of tightly packed spindle-shaped cells. The epithelial
cells are polygonal and of squamoid type, with pale, eosinophilic cytoplasm and oval nuclei with distinct nucleoli and longitudinal grooving, which is commonly described as "coffee-bean" in appearance
DCIS vs IDC
#59 Heart Part I CAD+hypertension (no liver no lung in container) Refer to #51
Part II liver cirrhosis, lung pneumonia Refer to #23 and #42 or 52
#60 Lung Bronchopneumonia (Refer to #52)
#61 Heart - Stroke no brain normal organs (No idea what this means)
#62 Kidneys Glomerulosclerosis (GS)
Nodular GS, aka: Kimmelstiel Wilson lesion a/w diabetes. Pink hyaline in glomerular capillary loops, increase in mesangial matrix, basement membrane thickening
#71 Clear cell RCC renal cell carcinoma (VHL tumor suppressor gene mutation in 75% of cases). Paraneoplastic
syndrome = hypercalcemia
#72 Stomach GIST from interstitial cells of Cajal; The vast majority of GISTs carry a mutation either in the gene for
Seen kinase c-KIT (80% of cases) or platelet-derived growth factor receptor alpha (PDGFRA; 8% of cases)
tyrosine
Nuclear palisading
Histologic details of gastric schwannoma. A. Tumor cells show a microtrabecular architecture with interspersed fibromyxoid matrix. B. An example with a more solid
to fascicular pattern. C. Focal nuclear palisading. D. Moderate nuclear atypia was often focally present
#75 Testicle Seminoma lobulated soft tan/brown tissue: The serum markers of greatest value include: lactate dehydrogenase
isoenzyme 1 (LD1), alpha-fetoprotein (AFP), and human chorionic gonadotropin (HCG). The highest stage has the highest LD1.
Lobules of neoplastic cells with intervening stroma filled with lymphocytic infiltrate.
Seminoma cells are large with vesicular nuclei and pale watery cytoplasm.