Professional Documents
Culture Documents
ilias
Named reaction
Phenol reaction
Kolbes Reaction
Sodium phenoxide
on
heating with co2 at 400K
under a pressure of 47atmospheres followed by
acidification gives salicylic
acid
Reimer-Tiemann
Reaction
Phenol
reacts
with
chloroform (CHCl3) in
presence of NaOH at
340K to form
of
phenol
The OH group activates the benzene ring
towards electrophilic substitution and directs
the incoming group to ortho- and parapositions due to resonance (+R effect), electron
density is more at ortho- and para- positions
Phenol to Asprin
From :mohammed.ilias
Account for :(a) Alcohols have higher boiling points than that of hydrocarbons.
Alcohols form intermolecular H-bonding while hydrocarbons are
held together by weak van der waals forces.
(b) Propanol has higher boiling point than that of the hydrocarbon, butane.
Propanol forms intermolecular H-bonding but butane does not
(c) Alcohols are comparatively more soluble in water than hydrocarbons of
comparable moleculer masses.
Alcohols form H-bonding with water but hydrocarbons do not.
(c) Ethanol has higher boiling point than methoxymethane
Ethanol forms intermolecular H-bond but methoxymethane does not
(d) Phenols are more acidic than alcohols .
Phenoxide ion is resonance stabilized but alkoxide ion does not
(e) Cresols are less acidic than phenols.
Cresol is methyl phenol ( o -, m- or p-cresol). Due to +I-effect of CH3 group
makes less stable phenoxide ion and cleavage of O H bond becomes difficult
as electron density in O-H bond increases. So release of H+ ion becomes
difficultas compared to phenol.
From :mohammed.ilias