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7-5 XX

3.

XX

25

Atopic dermatitis

2009/6/1

2009/06/02

2009/06/04

2009/06/06

2009/07/02

4.

2008/02/17 3

2008/08/10

2008/06/28

2008/08/30

2010/11/23

2010/09/29

2010/11/29

2012/08/03

16

49 2012/05/08

49 2012/05/24

2008/05/17 4

2008/08/29

2008/08/29
2008/05/XX

2013/07/24

2013/12/28

2012/03/24

2012/05/03

2012/06/07

autoimmune disease

DNA

Collagen
disease collagen

MTX




Crohn`s disease








Gullain Barre Syndrome, GBS








Nephrotic Syndrome

Collagen disease
Rheumatoid Arthritis, R.A.
S.L.E.
N.L.E.
Ankylosing spondylitis, A.S.
Polymyositis
Dermatomyositis
Raynaud's phenomenon
Behcet's Disease
Sjogrens syndrome, S.S.
scleroderma, P.S.S.
M.T.C.D.

Necrobiotic Xanthogranuloma

8-1 8-2 8-3


\
Widal/ Weil-Felix test
RA
HsCRP
C3 -3
C4 -4
IgA A
IgG G
IgM M
IgE E
ANA
MAST

8-1
Immunological Dis. Marker

Normal Range

T CellsCD3

50.0-84.0

Helper CellsCD4

27.0-51.0

Suppressor CellsCD8

15.0-44.0

B CellsCD19

5.0-22.0

CD16+56NK

7.0-40.0

Active T CellHLA-DR

1.9-19.6

WBC

10e3/uL

3.5-10.0

WBC Count

/uL

3500-10000

Lymphocyte

19.0-48.0

Lymphocyte count

/uL

660-4800

CD3 Absolute Count

/uL

723-2737

CD4 Absolute Count

/uL

404-1612

CD8 Absolute Count

/uL

404-1612

CD19 Absolute Count

/uL

404-1612

CD16+56 Absolute Count

/uL

84-724

Active T Cell Absolute Ct

/uL

RNF

Absolute count

CD4/CD8 Ratio

Ratio

0.7-2.7

8-2

E.S.R.
ANA Titer
ANTI-ENA-Ro/La Ab
Anti-nutrophil cytoplasmic Ab
Anti-ENA Sm/RNP Ab
ANTI-DS DNA
CRP-RIA
RF-RIA
C3-RIA
C4-RIA
ANCA
Anti-MPO
Anti-PR3
Anti-LA Antibody
Anti-Ro Antibody
HLA-B27
Anti-RNP Antibody
Anti-SM Antibody
Anti-SM & RNP Antibody
8-3

500

. autoimmune atopic dermatitis?


44

IgGE

8-4

8-4 XX IgGE

1.
2.
3. 2450%
4.

8-5

8-5 XX

1. IgGE

2.

3.
Over diagnosisover treatment

. purrlent psoriasis

XX

96


8-7
Prednesolone 6# /
dayMTXCyclosporin
8-11

358-12
48-13

8-6

8-8

8-7

8-9

8-10

8-11IgG

8-1235

8-13

1.

IgGE

2.

IgGEB

3.

4.

over
Diagnosis over reatment overmal

5.

Reference

. IgG

XX

36

Myasthenia Gravis

2012 2 7
6

2014 4 26

1 IgGE

8-14 XX IgGE

XX 2012 2 2 IgGE 2013 8 27

. Myasthenia GravisRheumatoid Arthvitis


IgG

XX

201516IgGEIgG
E

IgGEHRV

600 IGE

:2015/01/15

16:29

OO

8-15XXIgGEHRV

1. XX

2. HRV8-15HF
LF/HF

. sclerodermaRaynaud phenomenon

XX

61

2013 6 1 23.9 36.8


13.9 1
HRV
3D EEG

8-16
2013 6 29
2013
6 29 HRV 3D EEG

2014/06/01

2014/06/29

8-16 XX 28 3D EGG

8-17 XX 28
3D EGG

28

8-18

8-19

2013/06/01

2013/06/29

2013/06/01

2013/06/29

1648

711

937

1868

747

1121

926

458

468

999

436

563

1240

844

396

1201

840

361

821

645

176

726

636

90

4635

2658

1977

4794

2659

2135

8-20 XX 28

8-21 XX HRV

1. HRV
HRV
8-21
2.

3. HRV

4. EEG 8-16

5. meningitisencephalitis

6.

7. XX 1977 2135
8-188-198-20

. Iritis

XX

44

10

14

8-23 XX 14

8-22 XX EEG

EEG

14

8-24 XX

8-25 XX 14

EEG

EEG

14

8-26 XX

8-27 XX 14

2015/01/10

2015/01/24

2015/01/10

2015/01/24

1758

1228

530

1539

1214

325

648

397

251

481

376

105

1349

1406

-57

1206

1309

-103

890

973

-83

796

933

-137

4645

4004

641

4022

3832

190

8-28 XX EEG
14
3D EEG143D EEG8-228-23

H2+O2

1. good

prognosis

2. H2H2+O23

3.

FibromyalgiaEncephalopathic prupritis

4. 2015110EEG
20151245308-26
251325
105145783
1031378-27

5. EEG

H2

XX

autoimmune urticavia

2014 12 26
2015 1 19

2015 1 19

24

2014/12/26

2015/01/19

24

2014/12/26

2015/01/19

24

2014/12/26

2015/01/19

24

2014/12/26

2015/01/19

1.
2. IgEIgG

3. IgEIgG
4.

5.
ESRRA hsCRP

6. H2H2


Reference
H2+O2 Reference
echolalia


Reference

H2

1.

ADHD

2.

irreversible

H2

H2 H2
H2

9-2

H2

H2+O2

9-1

H2+O2
() 9-2

9-2

H2+O2

H2+O2 OH

H2 OH H2O
H2

9-3


Norepinephrine, NE

Lipopolysacharide, LPS
monocytes
macrophagesM
Tumor Necrosis Factor-, TNF-
TNF- cytokinesIL-1IL-8
NF-KB NF-KB
TNF-NF-KB

NK-KB P53
NF-KB Nuclear Factor - Kappa B NF-KBP53
Protein 53 53 P53NF-KB
P53

NF-KB NF-KB

NF-KB

NF-KB
NF-KB
NF-KB

P53
P53

50~60
P53
P53 NF-KB
P53 P300and CBP P300and CBP
NF-KB NF-KB P53 P53 P300
and CBP P53 NF-KB
NF-KB P300and CBP P53
NF-KB P53

TNF-
TNF-TNF- NF-KB
NF-KB P53 NF-KB P53

NF-KB IL-8 VEGF

P53

M
TNF-

NF-KB

9-4 TNF- NF-KB P53

TNF-
TNF- cytokines
IL-1 Tumor-Associated-MacrophagesTAM
TAM
TNF-

HRV
LFHF LF/HF /
LF/HF

1.

EB Virus B
NF- KB P53
2.
IgGIgE
NF- KB P53

3.
LF/HF

LF/HF Allostatic State

H2
1.

Cholinergic Anti-inflammatory
Pathway TNF-IL-1

Acetycholine, Ach Ach


TNF-IL-1

TNF-IL-1 NF-KB
P53

0.25g C18-3 H2+O2


HFLF

2. H2
20c.c 20c.c. H2O
H2+O2 O2 H2 O2
NK-Tcell O2
H2+O2 NK-Tcell NK-T

cell OH
H2 H2O2OH +H2
2H2O H2 H2+O2
H2+O2

2014 9 28 36
H2+O2
11 23

H2+O2 7

O2 H2 OH

2OH +H22H2O O2 NK-Tcell O2


H2

YouTube How Cells Obtain Energy ATP

a.

b.

H2

c.

H2

ASD

Autistic Spectrum Disorder, ASDASD

Attention Deficit Disorder, ADD


Attention Deficit Hyperactivity Disorder, ADHD
Tourettes syndrome
Aspergers syndrome
Atypical Autism
Autism

10-1

3D EEG

EEG

EEG

Tourettes syndromeTic

Tic
EEG
Leaky LungLeaky Gut

Blood Brain Barrier, BBB

microglia

macrophage

13Hz~30Hz

3D
3D EEG


Youtube

Attention Deficit Hyperactivity Disorder, ADHD


ASD
Hyperactive disorder, HD

ADHD

ADHD
ADHD ADHD
3D EEG
24 4
H2+O2

Hydrogen challenge test reverse positive

easy diagnosis

easy cured 24

Aspergers syndrome

1943 Kenner 1944 Asperger


Aspergers Syndrome

1.

ADD mental
retardation
2. ADHD

3. 3D EEG
ADHD HD
4. 6

ADHD

IgGIgE
H2+O2
99%

ADD
ADD

TouretteADHD
Tourettes Syndrome

99%

1.

13~30Hz

11-1

11-2

2.
EEG HRV

Youtube

3.
.
. 50%

.
. C18-3
. H2+O2
.
4.
12

5.

XX 12

2013 1 19

3D
11-3 11-4

11-3 XX 2013/01/19 EEG

11-4 XX 2013/01/19 EEG


Youtube
11-5
11-6

11-5 xx GE224

11-6 xx GE224

2013 4 9 3D 11-7

11-7 XX 2013/04/09 EEG

1. 99%
2.

ADHD
Attention Deficit Hyperactivity Disorder, ADHD

1.

ADHD

XX

3D EEG

11-8 XX GE224

11-9 XX

11-10 XX

11-11 XX 5

11-12 XX 5

11-13 5
1 30

11-14 5
03 57

14.7%
7.71%

11-15 XX EEG

11-16 XX 5 EEG

SDNN83.92

SDNN20.59

11-17 HRV

11-19 HRV

11-185 HRV