GENERIC

NAME

BRAND
NAME

ACTION

INDICATION & CONTRAINDICATION

DOSAGE
Adult : PO Schi Misuse or Excessive
Residents Name: Mio Franco S. Quilit
Risperd Description: Risperido zophrenia Initi Use of Drugs,
2015
RISPERIDON al
ne is an atypical
al: 2 mg/day,
Parkinson
E
antipsychotic. Its
up toDRUG
4
Symptoms,
STUDY
activity is mediated
mg/day on the Abnormal
through a combination 2nd day if
Movements of Face
of dopamine (D2) and
needed. May
Muscles and
serotonin (5-HT2)
further adjust
Tongue, Neuroleptic
receptor antagonism.
doses at wkly
Malignant
It also exhibits affinity intervals.
Syndrome, Tobacco
to adrenergic (1and
Maintenance:
Smoking, Metabolic
2) and histamine (H1) 4-6 mg/day.
Syndrome X,
receptors. It is less
Max: 16
Dementia in an
likely to cause
mg/day.
Elderly Person,
extrapyramidal effects
Diffuse Lewy Body
than conventional
Acute manic
Disease, Cataract
antipsychotics.
episodes of
Surgery,
Pharmacokinetics:
bipolar
Intraoperative
Absorption: Readily
disorder Initial: Floppy Iris
absorbed from the GI
2-3 mg once
Syndrome, Heart
tract (oral); peak
daily. May
Attack, Disease of
plasma concentrations increase
Inadequate Blood
after 1-2 hr.
slowly if
Flow to the Heart
Distribution: Proteinneeded. Max:
Muscle, Abnormal
binding: 90%
6
Heart Rhythm,
(risperidone), 70% (9- mg/day. IMSchi Chronic Heart
hydroxyrisperidone).
zophrenia Give Failure, Disease of
Metabolism: Extensive oral
the Heart and Blood
ly hepatic by
risperidone for Vessels, Abnormal
hydroxylation.
a few days to
EKG with QT
Excretion: Mainly in
assess
changes from Birth,
the urine and, to a
tolerability
Stroke, Any
lesser extent in the
before IM inj.
Disorder of the
faeces.
Blood Vessels of the
For patients
Brain, Blood
not stabilised
Pressure Drop Upon
on oral
Standing,
risperidone or Abnormally Low

ADVERSE
REACTION
Agitation,
anxiety,
dizziness,
headache,
somnolence
; orthostatic
hypotension
;
constipation
, dyspepsia,
nausea,
vomiting,
abdominal
pain,
blurred
vision,
erectile
dysfunction,
priapism,
rhinitis,
rash and
allergy,
galactorrho
ea,
gynaecoma
stia,
menstrual
disorders,
extrapyrami
dal
symptoms
(rarely).
weight gain,
oedema,
tardive
dyskinesia.
Potentially
Fatal: Neuro

NURSING
RESPONSIBILITY
An
effective
ETD:
August 10,
nurse should
first identify and
practice the
rights of
patients such
as: right
patient, right
drug, right
dosage, right
route and right
time ,
administration
and
documentation
In cases any
adverse drug
reaction and
side effect
either good or
bad caused by
medication
error, allergy
and/or toxicity
on any
unspecific drug.
One nurse
should easily
identify the
cause and
effect it may
bring and
immediately
refer it to the
attending
physician and
properly

Residents Name: Mio Franco S. Quilit

2015

ETD: August 10,

DRUG STUDY