Professional Documents
Culture Documents
Etiology and
Epidemiology
Absence of three base pairs of codn 508 that codes for phenylalanine on
chromosome 7, 70-75% of patients with cystic fibrosis
Mucus blocks the passageways of pncreas, preventing enzymes from pncreas
from reaching the intestines.
Most men with cystic fribrosis are infertile
Fertility is decreased in women with CF secondary to thick cervical mucus.
Newborn Screening
Sweat Test
Molecular Diagnosis
Nasal Potential Differences
Prenatal Testing
Stool Fecal Fat Test
Diagnostic Tests
Clinical Manifestations
General Management
Wheezing
Chronic cough
Sputum production
Frequent respiratory infections
Digital clubbing
Gastrointestinal disorders
Delayed growth
Respiratory Care
Treatment Protocols
Medical Treatments
(i.e. medications, etc)
Complications
National Education,
Initiative and
Prevention Programs
ciproflxacin, levofloxcain.
Ibuprofen-recommended in children and Young adolescent with mild CF-reduces
broncial inflmmation without hindering bacterial clearance decreases
neutrophil migration and inflammation in the lungsnot reccomended after the
age of 13
Inhaled corticosteriods/Systemic Glucocorticoids
Systemic glucorticoids are not recommended in children and adolescents-benefits
outweighed by adverse effects
Inhaled has not shown any clear benefits and therefore is not recommended
Coughing up blood
Diabetes
Infertility
Malnutrition
Chronic respiratory failure
Pancreatitis
Reoccuring pneumonia
pneumothorax
Lung transplant
Heart-lung transplant
Cystic fibrosis foundation