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This is a reprint of a Cochrane protocol, prepared and maintained by The Cochrane Collaboration and published in The Cochrane
Library 2012, Issue 11
http://www.thecochranelibrary.com
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
TABLE OF CONTENTS
HEADER . . . . . . . . . .
ABSTRACT . . . . . . . . .
BACKGROUND . . . . . . .
OBJECTIVES . . . . . . . .
METHODS . . . . . . . . .
REFERENCES . . . . . . . .
APPENDICES . . . . . . . .
HISTORY . . . . . . . . . .
CONTRIBUTIONS OF AUTHORS
DECLARATIONS OF INTEREST .
SOURCES OF SUPPORT . . . .
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School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
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[Intervention Protocol]
of Primary Care, University of Nottingham, Nottingham, UK. 2 School of Nursing, University of Nottingham, Nottingham,
UK
Contact address: Elizabeth Orton, Division of Primary Care, University of Nottingham, Room 1313, Tower Building, University Park,
Nottingham, NG7 2RD, UK. elizabeth.orton@nottingham.ac.uk.
Editorial group: Cochrane Injuries Group.
Publication status and date: New, published in Issue 11, 2012.
Citation: Orton E, Watson MC, Mulvaney C, Kendrick D. School based education programmes for the prevention of unintentional injuries in children and young people. Cochrane Database of Systematic Reviews 2012, Issue 11. Art. No.: CD010246. DOI:
10.1002/14651858.CD010246.
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
ABSTRACT
This is the protocol for a review and there is no abstract. The objectives are as follows:
To evaluate the effects and cost-effectiveness of school-based education programmes to prevent unintentional injuries in children and
young people with respect to child characteristics, intervention type and duration.
BACKGROUND
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
injury prevention, there are Cochrane reviews showing that schoolbased interventions can improve specific injury-prevention safety
practices, such as cycle helmet wearing (Owen 2011) and improve
knowledge, such as attitudes towards dogs to prevent bite injuries
(Duperrex 2009). However, whilst there have been reviews of the
effectiveness of school-based education to prevent specific types
of injury (e.g. Duperrex 2009; Miller 2009) or prevent injuries in
specific locations such as the home (Kendrick 2007a) but to date
the evidence for the effectiveness of school-based education for the
prevention of a wide range of injuries has not been systematically
reviewed as a Cochrane review.
OBJECTIVES
To evaluate the effects and cost-effectiveness of school-based education programmes to prevent unintentional injuries in children
and young people with respect to child characteristics, intervention type and duration.
METHODS
Types of studies
Randomised controlled trials (RCT) and non-randomised
controlled trials.
Controlled before-and-after studies (prospective studies
with a concurrent control group allocated using a non-random
method and with a baseline period of assessment of main
outcomes).
The control group will either receive no intervention, a delayed
injury-prevention intervention or alternative curricular activities
(school-based).
Studies other than RCTs have been included because as with many
public health interventions, an assessment of the effectiveness of
injury prevention interventions is often not undertaken using a
RCT design. Restricting the review to RCT studies alone will result
in a small number of included studies.
To assess the cost effectiveness we will include full economic
evaluations (i.e. cost-effectiveness analyses, cost-utility analyses,
cost-benefit analyses) of injury prevention programmes and their
comparators or partial economic evaluations of school-based
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Types of participants
Primary outcomes
Types of interventions
Secondary outcomes
Primary and secondary injury prevention education aimed at reducing a range of unintentional injuries, delivered in full or in part
in a school or preschool setting and delivered by a teacher or other
individuals with an injury prevention role.
Primary interventions are defined as those targeted at preventing
an incident in which an injury can occur. They include interventions to prevent injury in any setting. Secondary interventions are
those that are aimed at reducing the risk of injury once an event
has occurred e.g. a smoke alarm may prevent injury but will not
prevent the fire.
Excluded
Electronic searches
The Cochrane Injuries Group Trials Search Co-ordinator will
search the following databases:
Cochrane Injuries Group Specialised Register (to latest
version);
Cochrane Central Register of Controlled Trials (The
Cochrane Library) (latest issue)
Economic Evaluation Database (EED) (The Cochrane
Library) (latest issue)
Health Technology Assessment Database (HTA) (The
Cochrane Library) (latest issue)
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
We will search the Internet for grey literature using the search engines Google http://www.google.co.uk/ and Google Scholar http:/
/scholar.google.co.uk/
Selection of studies
Two authors from the review team will independently judge the
eligibility of studies by assessing the titles and abstracts. Full text
copies of all potentially relevant studies will be obtained and the
authors will independently assess whether each meet the pre-defined inclusion criteria. Any disagreement will be resolved by discussion with a third author from the review team.
We will attempt to translate the title and abstract of studies published in a language other than English that may be eligible prior
to screening.
Two authors from the review team will independently assess the
quality of included studies using the Cochrane Collaborations
tool for assessing the risk of bias. Decisions will be compared and
disagreements resolved through consultation with a third author.
For randomised controlled trials the risk of bias will be assessed by
taking into account the random sequence generation, allocation
concealment, blinding of participants and personnel, blinding of
outcome assessment and completeness of data, selective reporting
and other sources of bias. For non-randomised studies this will
include an assessment of selection bias, observation bias and control of confounders. The authors will complete risk of bias tables
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
efficient (ICC) is not reported we will use estimates from pervious studies of injury prevention interventions (Kendrick 2004;
Kendrick 2007b; Mulvaney 2006). We will use a coefficient of
variation of 0.25 (Hayes 1999). For dichotomous outcomes the
number experiencing the event and the number of participants
will be divided by the design effect. For continuous outcomes the
number of participants will be divided by the design effect. For rate
outcomes the number of events and the number of person years
will be adjusted for clustering using the variance inflation factor
calculated using the formula given by Donner and Klar (Donner
2000).
Dealing with missing data
Attempts will be made to obtain missing data from the authors.
During data extraction we will note where standard errors or standard deviations have not been identified and where possible, will
derive standard deviations from confidence intervals, P values or
standard errors. We will undertake a complete case analysis where
data are missing and cannot be derived.
Assessment of heterogeneity
Studies that are clinically heterogeneous will not be combined.
Where it is appropriate to combine studies heterogeneity will be
assessed by observation of forest plots, by using the I-squared statistic and by the chi-squared test for heterogeneity with a p value of
<0.01 taken as statistically significant. Where significant heterogeneity exists findings will be interpreted with caution. A-priori
sub group analyses will be undertaken to explore possible reasons
for heterogeneity.
Assessment of reporting biases
If it is possible to conduct a meta-analysis, a funnel plot will be
generated to show the effect size and 95% confidence interval for
each study, sorted by variance of the log odds ratio. Where there
are 10 or more studies in a meta-analysis a statistical test such as
the Eggers test will be used.
Data synthesis
Where there are three or more clinically homogenous studies reporting the same outcome we will combine effect sizes in metaanalyses. We will estimate pooled rate ratios for injury rates, pooled
risk ratios for binary outcome variables and mean differences or
standardised mean differences for continuous outcomes, with their
95% confidence intervals. Random effects models will be used to
allow for heterogeneity between effect sizes.
If it is not possible to conduct a meta-analysis a narrative review
with subgroups will be undertaken. Subgroups will include age
of the child/school setting and the type of intervention delivered
(e.g. information giving, skills training etc).
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
For example, studies have shown that the risk of different types of
injuries change as children mature and their environment changes
(WHO 2008a) and so the focus of injury prevention interventions
and their effectiveness is likely to change with age also. In addition
Owen 2011 showed that the likelihood of children wearing a cycle
helmet varied depending upon the type of intervention offered
(e.g. whether or not a free helmet had been provided or if the
intervention was community-based interventions) (Owen 2011)
and studies of other school-based prevention interventions, such
as preventing substance misuse (Broening 2012), weight gain (
Silveira 2011) and sexual abuse victimisation (Rispens 1997) have
show that the duration of the intervention is important.
Sensitivity analysis
We will perform sensitivity analyses by re-running the analyses and
excluding studies with a high or unclear risk of bias. In particular
we will perform sensitivity analyses for the quality of randomisation according to allocation concealment, detection bias based on
blinded outcome assessment and retention bias based on losses to
follow up.
REFERENCES
Additional references
Audit Commission 2007
Audit Commission. Better safe than sorry, Preventing
unintentional injury to children. ISBN 1 86240 529 8
February 2007:174.
Broening 2012
Broening S, Kumpfer K, Kruse K, Sack PM, SchaunigBusch I, Ruths S, Moesgen D, Pflug E, Klein M, Thomasius
R. Selective prevention programs for children from
substance-affected families: a comprehensive systematic
review. Substance Abuse, Treatment, Prevention Policy June
2012;7(1):Epub ahead of print.
Davis 1997
Davis A, Bamford J, Wilson I, Ramkalawan T, Forshaw
M, Wright S. A critical review of the role of neonatal
hearing screening in the detection of congenital hearing
impairment. Health Technology Assessment 1997; Vol. 1,
issue 10:1177. [: DARE11998008284]
Dobbins 2009
Dobbins M, DeCorby K, Robeson P, Husson H, Tirilis
D. School-based physical activity programs for promoting
physical activity and fitness in children and adolescents aged
6-18. Cochrane Database of Systematic Reviews 2009, Issue
1. [DOI: 10.1002/14651858.CD007651; : CD007651]
Donner 2000
Donner A, Klar N. Design and analysis of cluster
randomization trials in health research. Vol. Chapter 6.2,
pp 84-100, London: Arnold, 2000.
Duperrex 2009
Duperrex O, Blackhall K, Burri M, Jeannot E. Education
of children and adolescents for the prevention of dog bite
injuries. Cochrane Database of Systematic Reviews 2009,
Issue 2. [DOI: 10.1002/14651858.CD004726.pub2; :
CD004726]
Faggiano 2005
Faggiano F, Vigna-Taglianti F, Versino E, Zambon A,
Borraccino A, Lemma P. School-based prevention for illicit
drugs use. Cochrane Database of Systematic Reviews 2005,
Issue 2. [DOI: 10.1002/14651858.CD003020.pub2; :
CD003020]
Hayes 1999
Hayes RJ, Bennett S. Simple sample size calculation
for cluster-randomized trials. International Journal of
Epidemiology 1999;28:31926.
Kendrick 2004
Kendrick D, Royal S. Cycle helmet ownership and use;
a cluster randomised controlled trial in primary school
children in deprived areas. Archives in Diseases and
Childhood 2004;89:3305.
Kendrick 2007a
Kendrick D, Coupland C, Mason-Jones Amanda J,
Mulvaney C, Simpson J, Smith S, et al.Home safety
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Rispens 1997
Rispens J, Aleman A, Goudena PP. prevention of child
sexual abuse victimization: a meta-analysis of school
programmes. Child Abuse and Neglect 1997;21(10):97587.
Sattin 2007
Sattin R, Corso PS. The epidemiology and costs of
unintentional and violent injuries. In: Doll LS, Bonzo
SE, Mercy JA, Leet DA editor(s). Handbook of injury and
violence. 1st Edition. Vol. chapter 1, Springer, 2007:pp7.
Silveira 2011
Silveira JA, Taddei JA, Guerra PH, Nobre MR. Effectiveness
of school-based nutrition education interventions to
prevent and reduce excessive weight gain in children and
adolescents: a systematic review. Journal of Pediatrics (Rio J)
SeptOct 2011;87(5):38292.
Thomas 2006
Thomas RE, Perera R. School-based programmes for
preventing smoking. Cochrane Database of Systematic Reviews
2006, Issue 3. [DOI: 10.1002/14651858.CD001293.pub2;
: CD001293]
Tobler 1986
Tobler NS. Meta-analysis of 143 adolescent drug prevention
programs: Quantitative outcome results of program
participants compared to a control or comparison group.
Journal of Drug Issues 1986;16(4):53767.
WHO 2008a
World Health Organization. World report on child injury
prevention. WHO, Geneva 2008.
WHO 2008b
World Health Organization. The global burden of disease;
2004 update. WHO, Geneva 2008. [: ISBN 978 92 4
156371 0]
WHO 2011
World Health Organization. Child injury prevention
resolution A64/23. Sixty-fourth world health assembly 17
March 2011.
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
APPENDICES
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
HISTORY
Protocol first published: Issue 11, 2012
CONTRIBUTIONS OF AUTHORS
EO is the guarantor and co-ordinator of the review. All authors have contributed to the development of the objectives and methods
and have commented on the background sections of the protocol.
DECLARATIONS OF INTEREST
Elizabeth Orton is the public health representative from NHS Nottingham City on the steering group for the Nottingham injury
minimisation programme (IMPs) that is delivered in part in the school setting. There are however no financial incentives related to this
work and her future employment is not dependent upon the continued funding of the IMPs programme by NHS Nottingham City.
Denise Kendrick is the author of some studies that may be included in the review.
Caroline Mulvaney and Michael Watson: None known.
SOURCES OF SUPPORT
Internal sources
Elizabeth Orton, UK.
Salary paid by the University of Nottingham and the East Midlands NHS Healthcare Workforce Deanery
Denise Kendrick, UK.
Salary paid by the University of Nottingham
Michael Watson, UK.
Salary paid by the University of Nottingham
Caroline Mulvaney, UK.
Salary paid by the University of Nottingham
External sources
No sources of support supplied
School based education programmes for the prevention of unintentional injuries in children and young people (Protocol)
Copyright 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.