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ABSTRACT
Background : According to World Health Organization 2008, cancer is the leading
cause of mortality in the world, which is approximately 13 %. The risk of patients
attaining opportunistic infections with neoplastic disease increases due to their
immunocompromised condition.
Objective : This research is done to investigate the prevalence of protozoal
infection in cancer patients at Haji Adam Malik General Hospital, Medan.
Methods : This study is performed in a descriptive cross sectional manner on 38
consecutive patients who is undergoing cancer therapy. Fecal samples are collected
and tested in laboratorium using the Kato method and Kinyoun Gabbet staining.
Data were analysed using the SPSS version 17.0 programme.
Results : From the research done, it is known that the prevalence of protozoal
infection in cancer patients at Haji Adam Malik General Hospital is 7,9 % which
indicates the positive result for 3 samples out of 38 fecal samples which were tested.
Cryptosporidium sp. oocyst was found in one of the 3 samples and the rest of the 2
samples show the existence of Entamoeba histolytica cyst. All the 3 positive samples
were found in the same age group which is more than 60 years (60 %) and
undergoing the combination of chemotherapy and radiotherapy (27,3 %). 2 of the
samples belong to female (9,5 %) while the other is male (5,9 %). According to the
staging of cancer, 2 of the positive samples belong to the patient whose at stage 4
(20 %) and the other is at stage 3 (6,7 %).
Conclusion : Based on the research done, it can be concluded that age group, type of
therapy and the staging of cancer significantly influences the occurance of
opportunistic infections among cancer patients.