1.

Explain Uses of
Epinephrine
Dopamine
Dobutamine
Alpha1 agonists
2. Classify Beta blockers
3. What are the adverse effects beat1 selective blockade
4. What are the adverse effects beat2 selective blockade
5. Withdrawal reaction with beta blockers
6. Uses of beta blockers
2. Explain the pathophysiology of

Stable angina ( acute & chronic)

Unstable angina
Myocardial infarction
Variant angina

2. Name drugs used to treat stable angina

Acute attack
Chronic prophylaxis
1. Explain the basis for using nitrate to relieve acute attack of stable angina?
2. Explain the basis for using following drugs in chronic prophylaxis of stable angina
Beta blockers
Calcium channel blockers
Nitrates
Ranolazine
Statin
Low dose aspirin
3. Name the drugs used to treat variant angina with pharmacological basis
4. What drugs are used to treat an acute attack of unstable angina with basis?
5. What drugs are used to treat an acute attack of MI with basis for each?
6. What are the other uses of nitrates?
7. What are the different routes of administration of nitrates?
8. What are the limitations of nitrates
9. Classify calcium channel blockers ( DHP & Non DHP)
10. Mention the uses of different calcium channel blockers
11. Mention the adverse effect seen with different CCB
12. Explain the basis for using using following drugs for treatment of HTN
Central sympatholytic drugs (clonidine & methyl dopa)
Adrenergic receptor blockers alpha1 & beta1 blockers
Calcium channel blockers
Drugs modulating RAAS ACEI, ARB

 Diuretics- Thiazides, K sparing

Direct vasodilators
13. Explain the advantages & limitations of each of above drug
14. Advantages of drug combinations in HTN
15. Drugs safe during pregnancy
16. Drugs used to treat hypertensive emergency
17. Classify diuretics
18. What are the uses of Diuretics in general
19. How do loop diuretics act? List the toxic effects List the uses
20. Explain mechanism of action of Thiazides? List the toxic effects. List the uses
21. How Probenecid decreases the efficacy of frusemide/ thiazides
22. What are the differences between Spironolactone (S) & Eplerenone (E)?
23. List the uses of Aldosterone antagonists
24. In what way Triamterene and Amiloride differ from Aldosterone antagonists
25. Explain the rationale for using Thiazides + potassium sparing diuretics?
26. Why avoid DMRAAS & potassium sparing diuretics together?
27. Explain the basis for using Mannitol in different clinical conditions
28. Name drugs used to treat acute attack of bronchial asthma
29. Which is the first choice drugs to treat chronic asthma
30. Which are add on drugs to treat chronic asthma
31. What is metered dose inhaler (MDI)
32. What are the advantages of administering drugs by inhalation route?
33. What are the most important kinetic features of drugs that are meant for
administration by MDI
34. What are the limitations of different drugs used to treat asthma
Beta 2 agonists (SABA & LABA)
Methylxanthines
Antimuscarinic drugs
Corticosteroids
Leukotriene antagonists
IGE antagonist
Beclometahsone
35. Classify corticosteroid preparations based on duration of action
36. Precautions to minimize HPA axis supression
37. Mention the non-endocrine uses of corticosteroids
38. Explain the basis of using corticosteroids in autoimmune and collagen disorders
39. Mention the toxicities of corticosteroids and the basis for these toxicities
40. Mention the use of 2nd generation non-sedative H1 blockers
41. Mention the uses of 1st generation ( sedative ) H1 blockers
42. Explain the rationale for each use of the above
43. Explain the differences between the 1st and 2nd generation H1 blockers
44. Explain the limitations of 1st generation H1 blockers
45. Which drugs are used to treat constipation?
46. Which laxatives produce effect within 3-4 hours
47. Which laxatives are used prior to preoperative preparation abdominal surgery
48. Which drugs are administered by rectal route?

49. What are different mechanisms by which laxatives act

50. Name anti motility drugs. Why atropine is combined with diphenoxylate
51. Name quick acting high efficacy blood schizonticidal antimalarial drugs
52. Name slow acting low efficacy blood schizonticidal antimalarial drugs
53. What drugs can be used to treat ( quick acting, high efficacy & long acting )
vivax
chloroquine sensitive falciparum
chloroquine resistant falciparum un complicated / complicated
54. what are the AE of antimalarial drugs
55. What is the rationale for using Primaquine in vivax and in falciparum malaria
56. What are limitations of Primaquine?
57. What are the uses of metronidazole
58. What are the limitations of metronidazole
59. Which drug is used to treat prevent carrier state of amoebiasis?
60. Which drug is used in addition in hepatic amebiasis?
61. Name the drugs for filariasis
62. Name the drugs for hook worm, tapeworm, infections