Annals of Library and Information Studies

Vol. 58, September 2011, pp. 237-248

Research output on Artemisia (Artemisia annua): a bibliometric study

Shri Ram
Deputy Librarian, Jaypee University of Information Technology, Waknaghat, Solan 173234 (Himachal Pradesh),
Email: shriram2576@gmail.com
Artemisia is a herb that yields a natural component known as Artemisinin which is being used for the treatment of
Malaria worldwide. This paper uses data indexed in the PubMed database for the period of fifteen years (19962010) to
study the research on Artemisia. It has been found that publications on this subject grew to 712 percent in 2010 as compared
to 1996. China is one of the countries that has contributed a number of publications in this area. In India, Central Institute of
Medicinal and Aromatic Plants (CIMAP), Lucknow, Uttar Pradesh is a leading contributor of literature on Artemisia.

Introduction
Artemisia belongs to the tribe Arthemideae of the
subfamily Asteroideae of Asteraceae. Artemisia is a
large diverse genus of plants with 200-400 species1.
The species Artemisia annua is an annual herb that
grows naturally in the northern part of Chahar and
Suiauan provinces of China at around 1000-1500 m
above sea level. It is now naturalized in many
countries such as USA, Yugoslavia, Hungary,
Bulgaria, Romania, Turkey, Argentina, Italy, France
and Spain and India.
Artemisia annua is the source of Artemisinin and
chemically, Artemisinin is a sesquiterpene lactone
containing an unusual peroxide bridge. It is believed
that this peroxide is responsible for the drug's
mechanism of action. It is efficient against multidrug
resistant strain of Plasmodium, the malaria parasite2,3.
Governmental and non-governmental organizations,
medical research centers and Food and Health
Organizations are working in close coordination with
research and development institutes to harness the
medicinal values of this plant especially in producing
herbal products. World Health Organization (WHO)
on advice of international experts has recommended
combinations of drugs to replace single drug use in
treatment of malaria caused by Plasmodium
falciparum4.
It is estimated that about 3.3 billion people - half of
the world's population - are at a risk of malaria. Every
year, it leads to about 250 million malaria cases and
nearly one million deaths. People living in the poorest

countries are the most vulnerable. WHO in its policies

have made provision and recommended Rapid
Diagnostic Test (RDT) to all patients suspected of
suffering from malaria. As per the guidelines framed
by WHO, confirmed cases of Plasmodium falciparum
malaria must be treated with an Artemisinin-based
combination therapy (ACT)5,6.
Malaria is a serious problem especially in Africa,
where one in every five (20%) childhood deaths is
due to the effects of the disease. An African child has
on average between 1.6 and 5.4 episodes of malaria
fever each year, and every 30 seconds a child dies
from malaria. Food and Drug Administration (FDA),
USA has decided to use the drug Coartem (a
combination drug of two ingredients, a chemical
derivative of Artemisinin and lumefantrine, a broadspectrum antibiotic that stays in the body for about
seven days) as part of an expedited review reserved
for life-saving treatments of Malaria. Coartem is the
most effective treatment for Plasmodium falciparum
malaria, the most lethal form7,8. According to drugmaker Novartis, Coartem wipes out malaria in more
than 96 percent of patients in regions where malaria
has become resistant to older drugs. Traditional
medicines such as chloroquine work in only 50
percent of patients where the parasite is drugresistant.
According to the WHO statistics there were an
estimated 247 million malaria cases in 2006 out of
which nearly 881,000 patients died. Wormseed
(Artemisia absinthium) is another species of
Artemisia being used as powerful biological agent

ANN. LIB. INF. STU., SEPTEMBER 2011

238

against fungi, bacteria and even some harmful insects.

Artemisia tea is also used for strengthening immune
system of AIDS patients. Scientists are working on
Artemisia for the treatment of haemorrhoids, eye
infections, bronchitis, skin complaints - as ointment,
digestion related problems, and as a supportive
treatment for cancer. The medicinal values have
attracted medical scientists as well as biological
scientific community to explore more of the potential
use of this plant for the purpose of medicinal use and
eradication of some of the life threatening diseases
such as AIDS and malaria.
The administration of Artemisinin initiated drugs for
eradication of malaria in India9, its antipyretic and
anti inflammatory effect; strengthening immune
system against AIDS10; cancer, as well as use of
Artemisia as herbal tea in Chinese community and its
other medicinal uses prompted this bibliometric study
on the research output on this plant.
Objectives of the study
The main objective of this study is to highlight the
publishing patterns and research output of Artemisia
during 19962010 indexed in PubMed (available at
http://ncbi.nlm.nih.gov/PubMed/). The specific objectives of the study are:

To find out the growth of publication during this

period;

To identify the country-wise distribution of

papers;

To analyze the type of publications;

To identify language-wise publication patterns;

To examine the productivity of

publishing papers related to Artemisia;

journals

To unfold the authorship patterns and productivity

amongst the publication of Artemisia; and

To report the Indian publication activity on

Artemisia.

Methodology
Data was collected from PubMed database of
National Center for Biological Information, USA.
Medical Subject Heading (MeSH) indexing terms
were used to extract bibliographic information. Search
was carried out based on the keywords (Table 1)
available in Title, MeSH terms, and Abstract
limiting the time period i.e., year 1996-2010 (Fifteen
Years) through advanced search feature of PubMed.
The search criteria yielded 1526 records for this
period. After removing irrelevant records which were
not related to Artemisia, 1484 records were used for
data analysis.
Data preparation
XML/XSL transformation scripts have been used for
data extraction and data preparation. XSLT
(EXtensible Stylesheet Language Transformations) is
a method used to convert XML document in any
desired style such as HTML, Excel or Text. XSL
processors transform whole XML documents into
another XML/HTML format according to XSLT style
sheets11. Here in this study XSLT is used to convert
XML document into HTML table, one of the
prerequisites of bibliometric analysis is to have the

Table 1MeSH indexing terms of Artemisia

MeSH Terms
Artemisias

Mugwort

Tarragon Plants

Artemisia abrotanum

Sagewort

Mugworts

Artemisia maritima

Artemisia abrotanums

Sageworts

Wormwood

Artemisia maritimas

abrotanum, Artemisia

Sagebrush

Wormwoods

maritima, Artemisia

abrotanums, Artemisia

Sagebrushs

Artemisia dracunculus

maritimas, Artemisia

Southernwood

Wormseed, Levant

dracunculus, Artemisia

Artemisia vulgaris

Southernwoods

Levant Wormseed

Tarragon Plant

Artemisia vulgari

Artemisia judaica

Levant Wormseeds

Plant, Tarragon

vulgari, Artemisia

Artemisia judaicas

Wormseeds, Levant

Plants, Tarragon

vulgaris, Artemisia

judaica, Artemisia

SHRI RAM: RESEARCH OUTPUT ON ARTEMISIA (ARTEMISIA ANNUA): A BIBLIOMETRIC STUDY

data in a table format. In order to convert PubMed

bibliographic data in to HTML table the following
steps were followed:
Step 1: Used web edition of PubMed available at
NCBI (http://ncbi.nlm.nih.gov/pubmed);
Step 2: Searching Artemisia publications using
advance search feature;
Step 3: Choosing Medline Format;
Step 4: Exporting bibliographic data as XML format
(Fig. 1).
Step 5: Design of XSL Transformation sheet using
XSL;
Step 6: Use of XSLT for the Transformation of XML
document into HTML Table (Fig. 2).
Analysis
Publication types

Artemisia related papers have been published in

variety of publication types. Table 2 depicts the
overall picture of various types of the Artemisia
publications as indexed in PubMed.
Majority of the papers have been published in the
form of journal articles. PubMed indexes publication
types under different headings such as research

239

support, English abstract, case studies, clinical trials,

etc. A total of 1228 publications amounting to 82.75
percent of articles are indexed as journal articles and
123 publications amounting to 8.29 percent papers are
comparative studies and the remaining literature
published differently as given in Table 2.
Language of publications

Majority of the papers have been published in English

language (89.22%). Table 3 shows that 7.95 percent
articles were published in Chinese, 0.81 percent
article came in Japanese language along with 0.74
percent in French and 0.34 percent in Russian.
Research output on Artemisia

A total of 1484 articles were published on Artemisia

during the period of fifteen years (1996 2010).
Table 4 and Fig. 3 shows there has been a consistent
growth during the period 1996-2010.
It is seen that from 25 articles in 1996, the research
output has grown to 203 articles in 2010 with an
increase in growth of 712 percent. This is an indicator
of global research interest in the field on Artemisia.
Country-wise distribution of publication in Artemisia

Table 4 shows the distribution of Artemisia

publications globally. Amongst the top 20 countries,

Fig. 1Typical Medline record in XML format

240

ANN. LIB. INF. STU., SEPTEMBER 2011

Fig. 2HTML table conversion using XML/XSL transformation with basic bibliographic information

Fig. 3Growth of literature on Artemisia indexed in PubMed

China contributes majority of the publications (24%)

followed by USA (16%), Korea (12%) and Italy (5%).
Other countries like Germany, Japan, Spain and India
have a share of 4 percent each. UK, France, Austria
and Iran have 3 percent; Argentina, Netherlands and
Canada shares 2 percent each, while south Africa,
Turkey, Sweden, Brazil, Egypt and Poland shares 1
percent of total publications.
Total of 52 countries are having its participation of
the Artemisia publications. Out of the total 1484
publications, 1312 publication (88.41%) of the
contribution came from these 21 countries listed in
Table 5 and remaining of about 11 percent of the

publications came from rest of the countries of the

world.
Authorship pattern

Table 6 gives the authorship patterns of Artemisia

publications published in PubMed during the period
of 1996-2010. It can be seen the table that majority of
the papers have joint authorship with a large number
of papers authored by two to twelve authors (Fig 4).
The distribution of the authorship pattern and
contributed papers is given in Table 7. There are 4040
(79.23%) authors who have contributed at least one
paper on Artemisia during the period of study, either

SHRI RAM: RESEARCH OUTPUT ON ARTEMISIA (ARTEMISIA ANNUA): A BIBLIOMETRIC STUDY

241

Table 2Types of Artemisia publication indexed in PubMed

Sl. no.
1
2
3
4
5
6
7
8
9
10
11
12
13

Publication types
Journal article
Comparative study
Case reports
Historical article
Clinical trial
Letter
In Vitro
Comment
Evaluation studies
Biography
Congresses
Editorial
Not available
Total

Total count

Percentage (%)

1228
123
26
21
18
16
15
13
11
5
1
1
6
1484

82.75
8.29
1.75
1.42
1.21
1.08
1.01
0.88
0.74
0.34
0.07
0.07
0.4
100

Fig. 4Authorship patterns

singly or in collaboration with the others. There are

eight authors who have ten or more than ten papers to
their credit.
Journal productivity

The 1484 Artemisia publications are distributed

amongst 482 journals published globally. Table 8
gives a ranking of top thirty journals in which ten or
more than ten documents on Artemisia are published.
Journal of Ethnopharmacology has published highest
number of 66 articles (4.45%) up to 2010.

Indias contribution to Artemisia research

India is one of the countries in the world where the
cases of malaria are prominent. The WHO in 2008
reported that there had been 10.6 million cases of
malaria and 15,000 deaths from this disease during
2006. There are various approaches applied by
scientists to estimate the global burden of P.
falciparum, one of which is Malaria Atlas Project12.
According to a report by scientists concerned with it,
the extent of disease caused by P. falciparum has
been about 102 million in 200713 in India. P.

ANN. LIB. INF. STU., SEPTEMBER 2011

242

Table 3Language of publication

Sl. no.
1
2
3
4
5
6
7
8
9
10
11
12
13

Language of Publications
English (Eng)
Chineese (Chi)
Japanese (Jpn)
French (Fre)
Russian (Rus)
German (Ger)
Polish (Pol)
Spanish (Spa)
Bosnian (Bos)
Mande language (dan) Spoken in Liberia
Dutch (Dut)
Korean (Kor)
Norvenian (Nor)
Total

Total Papers

Percentage (%)

1324
118
12
11
5
4
3
2
1
1
1
1
1
1484

89.22
7.95
0.81
0.74
0.34
0.27
0.20
0.13
0.07
0.07
0.07
0.07
0.07
100.00

Table 4Year-wise publication of Artemisia literature

Sl. no.

Year

No. of publications

Percentage

Cumulative percentage

1996

25

1.68

1.68

1997

30

2.02

3.71

1998

42

2.83

6.54

1999

39

2.63

9.16

2000

58

3.91

13.07

2001

61

4.11

17.18

2002

87

5.86

23.05

2003

84

5.66

28.71

2004

114

7.68

36.39

10

2005

117

7.88

44.27

11

2006

139

9.37

53.64

12

2007

136

9.16

62.8

13

2008

167

11.25

74.06

14

2009

182

12.26

86.32

2010

203

13.68

100

Total

1484

100

15

falciparum infections are particularly high in forested

areas, inhabited by ethnic tribes. These areas include
the states of Orissa, Jharkhand, Madhya Pradesh and
Chhattisgarh. The other type of malaria which is
caused by Plasmodium vivax (P. vivax) is usually less
lethal than P. falciparum. Almost half of the cases of
malaria in the country account for P. vivax.
Scientists are of the opinion that it is essential to
obtain a true picture of the burden of malaria in India
as it would enable to set up priorities in planning and

resource allocation of budget for its control and

gradual eradication. The National Anti-malaria
program was initiated in 1953. Over the last 54 years,
the problem of malaria has been effectively controlled
over the most parts of the country. The remaining
high endemic areas contribute 80 percent of burden of
disease in the country. These areas where P. vivax are
affecting Indian population is the remote and
inaccessible areas spread across the North Eastern
States, Orissa, Jharkhand, West Bengal, Chhatisgarh,

SHRI RAM: RESEARCH OUTPUT ON ARTEMISIA (ARTEMISIA ANNUA): A BIBLIOMETRIC STUDY

243

Table 5Country wise distribution of publication on Artemisia

Sl. no.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21

Country

Number of publications

China
USA
Korea
Italy
Germany
Japan
Spain
India
UK
France
Austria
Iran
Argentina
Netherlands
Canada
South Africa
Sweden
Turkey
Brazil
Egypt
Poland
Total

Percentage (%)

315
212
159
69
60
54
54
56
44
37
36
36
31
24
23
19
19
18
16
15
15
1312

21.18
14.26
10.69
4.64
4.03
3.64
3.64
3.77
2.96
2.49
2.43
2.43
2.09
1.62
1.55
1.28
1.28
1.21
1.08
1.01
1.01
88.41

Table 6Authorship distribution of articles on Artemisia

Number of authors

Number of articles

Number of authors

0
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
20
23
24
26
32
Total

3
88
181
221
258
231
152
133
77
35
40
26
16
10
4
3
1
1
1
1
1
1
1484

0
88
362
663
1032
1155
912
931
616
315
400
286
192
130
56
45
16
20
23
24
26
32
7324

244

ANN. LIB. INF. STU., SEPTEMBER 2011

Table 7Authors and their contribution of papers on Artemisia

Number of papers contributed

No. of authors

Percent (%)

1
2
3
4
5
6
7
8
9
10
11
12
13
Total

4040
760
164
57
36
18
5
7
4
3
3
1
1
5099

79.23
14.9
3.22
1.12
0.71
0.35
0.1
0.14
0.08
0.06
0.06
0.02
0.02
100

Table 8Top 30 Journals published more than ten articles on Artemisia

Sl. no.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30

Journals
Journal of Ethnopharmacology
Planta Medica
Zhongguo Zhong Yao Za Zhi = China Journal of Chinese Materia Medica
Ying Yong Sheng Tai Xue Bao = The Journal of Applied Ecology (Chinese)
Phytochemistry
Phytotherapy Research : PTR
Journal of Agricultural and Food Chemistry
Journal of Natural Products
Archives of Pharmacology Research
Allergy
Oecologia
Journal of Chromatography. A
Journal of Chemical Ecology
Natural Product Communications
Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
Zhong Yao Cai = Journal of Chinese Medicinal Materials
Fitoterapia
International Archives of Allergy and Immunology
Allergologia et Immunopathologia
Clinical and Experimental Allergy
Journal of Investigational Allergology & Clinical Immunology
Annals of Allergy, Asthma & Immunology
Biological & Pharmaceutical Bulletin
International Journal of Biometeorology
Archives of Biochemistry and Biophysics
Environmental Management
Food and Chemical Toxicology
Natural Product Research
Plant Cell Reports
Veterinary Parasitology

Papers published

Percent (%)

66
54
37
33
26
26
24
21
19
17
17
16
15
15
14
14
13
13
12
12
12
11
11
11
10
10
10
10
10
10

4.45
3.64
2.49
2.22
1.75
1.75
1.62
1.42
1.28
1.15
1.15
1.08
1.01
1.01
0.94
0.94
0.88
0.88
0.81
0.81
0.81
0.74
0.74
0.74
0.67
0.67
0.67
0.67
0.67
0.67

SHRI RAM: RESEARCH OUTPUT ON ARTEMISIA (ARTEMISIA ANNUA): A BIBLIOMETRIC STUDY

245

Fig. 5Contribution of Indian states on Artemisia research

Table 9Indian authorship patterns
Authorship patterns

No. of authors

Percent (%)

Cumulative percentage

0.47

0.47

18

8.41

8.88

42

19.63

28.5

64

29.91

58.41

45

21.03

79.44

30

14.02

93.46

14

6.54

100

Total

214

100

Rajasthan, Gujarat, Madhya Pradesh, Maharashtra,

and Andhra Pradesh14. Some of the strategies and
control of malaria adopted by Ministry of Health,
Government of India being implemented as early case
detection and prompt treatment (EDPT); integrated
vector
control;
information,
education,
communication towards personal prevention,

community
participation
management capacity building.

and

institutional

Research groups from the India have published many

works on the extraction of Artemisinin from its plant
source, Artemisia annua. Some key organization like
Central Institute of Medicinal and Aromatic Plants

246

ANN. LIB. INF. STU., SEPTEMBER 2011

Table 10Indian publications on Artemisia with more than 10 citations

Sl.
no.

1
2
3
4
5
6

9
10

11

12

13
14

15
16

17
18
19
20
21

Article

Total number
of citations
since
published

Dhingra V, Rao K Vishweshwar and Narasu, M Lakshmi Current status of artemisinin and its derivatives as
antimalarial drugs, Life Sciences, 66(4) (1999) 279-300.
Abdin, M Z, Israr, M Rehman, R U and Jain S K Artemisinin, a novel antimalarial drug: biochemical and
molecular approaches for enhanced production, Planta Medica 69(4) (2003) 289-299.
Thatte U, Bagadey, S and Dahanukar S, Modulation of programmed cell death by medicinal plants, Cellular
and Molecular Biology, 46(1) (2000) 199-214.
Tripathi A K, Prajapati V, Aggarwal K K, Khanuja S P and Kumar S, Repellency and toxicity of oil from
Artemisia annua to certain stored-product beetles, Journal of Economic Entomology, 93(1) (2000) 43-47.
Sriram D, Rao V S, Chandrasekhara, K V G and Yogeeswari, P, Progress in the research of artemisinin and
its analogues as antimalarials: an update, Natural Product Research, 18(6) (2004) 503-527.
Subramoniam A, Pushpangadan P, Rajasekharan S, Evans D A, Latha P G and Valsaraj R, Effects of
Artemisia pallens Wall. on blood glucose levels in normal and alloxan-induced diabetic rats, Journal of
Ethnopharmacology, 50(1) (1996) 13-17.
Tripathi A K, Prajapati V, Aggarwal K K and Kumar S, Toxicity, feeding deterrence, and effect of activity of
1,8-cineole from Artemisia annua on progeny production of Tribolium castanaeum (Coleoptera:
Tenebrionidae), Journal of Economic Entomology, 94(4) (2001) 979-83.
Sangwan R S, Sangwan, N S, Jain D C, Kumar S and Ranade S A, RAPD profile based genetic
characterization of chemotypic variants of Artemisia annua L, Biochemistry and Molecular Biology
International, 47(6) (1999) 935-344.
Sharma P, Mohan L and Srivastava C N, Phytoextract-induced developmental deformities in malaria vector.,
Bioresource Technology, 97(14) (2006) 1599-1604.
Dhingra V and Narasu, M L, Purification and characterization of an enzyme involved in biochemical
transformation of arteannuin B to artemisinin from Artemisia annua, Biochemical and Biophyscial Research
Communications, 281(2) (2001) 558-561.
Sen R, Bandyopadhyay S, Dutta A, Mandal G, Ganguly S, Saha P and Chatterjee, M, Artemisinin triggers
induction of cell-cycle arrest and apoptosis in Leishmania donovani promastigotes, Journal of Medical
Microbiology, 56(9) (2007) 1213-1218.
Senthilkumar N, Varma P and Gurusubramanian G, Larvicidal and adulticidal activities of some medicinal
plants against the malarial vector, Anopheles stephensi (Liston), Parasitology Research, 104(2) (2009) 237244.
Baldi A and Dixit V K, Yield enhancement strategies for artemisinin production by suspension cultures of
Artemisia annua, Bioresource Technology, 99(11) (2008) 4609-4614.
Bhandari P, Gupta A P, Singh B, and Kaul V K, Simultaneous densitometric determination of artemisinin,
artemisinic acid and arteannuin-B in Artemisia annua using reversed-phase thin layer chromatography,
Journal of Separation Science, 28(17) (2005) 2288-2292.
Sharma P and Sharma, J D, Plants showing antiplasmodial activity--from crude extracts to isolated
compounds, Indian Journal of Malariology, 35(2) (1998) 57-110.
Ram M, Gupta M M, Dwivedi S and Kumar S, Effect of plant density on the yields of artemisinin and
essential oil in Artemisia annua cropped under low input cost management in North-Central India, Planta
Medica, 63(4) (1997) 372-374.
Singh B, Srivastava J S, Khosa R L and Singh, U P, Individual and combined effects of berberine and
santonin on spore germination of some fungi, Folia Microbiologica, 46(2) (2001) 137-142.
Kapoor R, Chaudhary V and Bhatnagar A K, Effects of arbuscular mycorrhiza and phosphorus application
on artemisinin concentration in Artemisia annua L., Micorrhiza, 17(7) (2007) 581-587.
Banerjee S, Zehra M, Gupta M M and Kumar S, Agrobacterium rhizogenes-mediated transformation of
Artemisia annua: production of transgenic plants, Planta Medica, 63(5) (1997) 467-469.
Sukul N C, Ghosh S and Sinhababu S P, Reduction in the number of infective Trichinella spiralis larvae in
mice by use of homeopathic drugs, Forsch Komplementarmed Klass Naturheilkd, 12(4) (2005) 202-205.
Kiran U and Patra D D, Medicinal and aromatic plant materials as nitrification inhibitors for augmenting
yield and nitrogen uptake of Japanese mint (Mentha arvensis L. Var. Piperascens), Bioresource Technology,
86(3) (2003) 267-76.

150
98
85
65
60
51

28

27

23
24

31

22

20
16

16
15

14
14
13
11
10

SHRI RAM: RESEARCH OUTPUT ON ARTEMISIA (ARTEMISIA ANNUA): A BIBLIOMETRIC STUDY

(CIMAP), Lucknow, University of Delhi, Institute of

Himalayan Resource, Palampur, Himachal Pradesh
are working on Artemisia research. Figure 5 shows
the Indian states contribution to Artemisia research.
Table 9 presents the authorship patterns of Indian
authors contributing papers on Artemisia research.
Two hundred and fourteen authors have contributed
the 56 papers during the period of 1996-2010.
Table 10 present the status of Indian authors
contribution with more than 10 citations based on
citation count available through Google Scholar15. All
the 56 Indian publications were individually searched
at http://scholar.google.com and the number of
citation were noted down with more than 10 citations.
The article entitled Current status of artemisinin and
its derivatives as antimalarial drugs contributed by
Dhingra, V; Vishweshwar Rao, K; Lakshmi Narasu,
M, published in 1999, received the highest number of
citation i.e., 150 received as on the date of
communication of this paper.

247

supplement for the treatment of various diseases such

as P. falciparum and Plasmodium vivax malaria and
immune system related diseases such as AIDS. This
study is limited to some of the very basic bibliometric
analysis. Scientometric studies on Artemisia based on
other need to be carried out to compare with the
findings of the present study.
References
1.

http://en.wikipedia.org/wiki/Integrated_Taxonomic_Informat
ion_System (Accessed on 28 September 2011).

2.

Ro D K, Production of antimalarial drug precursor

Artemisinic Acid in engineered yeast, Nature, 440 (13)
(2006) 940-946.

3.

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(Asteraceae), including Artemisia and its allied and segregate
genera, BMC Evolutionary Biology, 2 (1) (2002) 1.

4.

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Available
at
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http://www.rollbackmalaria.org/cmc_upload/0/000/015/364/
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Conclusion
Artemisia is one of the important medicinal herbs
yields Artemisinin compound. It has been used in
China in the treatment of fevers for more than 1000
years. Artemisinin has a high therapeutic index in
treatment of the malaria. This compound is gaining
importance as it is now being administered globally
and research in Artemisia in growing as reflected in
this study. The publications of Artemisia mostly
appeared in the form of journals articles (87%) and in
English language (89.22%). There were 52 countries
participated in the research publication and China has
contributed highest number of articles with 315
(21.18%) and ranked number during the period of
study, where as Indias position is eighth with 56
publication spread over the period of 15 years. Most
of the papers have been written as joint authorship
and the authors collaboration is highest between 2 to
12 authors. Journal of Eethnopharmacology
published by Elsevier B.V. got highest number of
article published with 66 publications. The Indian
scientists too actively working in this area and their
contribution is being recognized globally. The article
published by V. Dhingra et al got highest number of
Google Scholar Citation (150 citations) since 1999
of its publication in the journal Life Science. The
medicinal value of Artemisinin is being used as a

7.

Facts of ACTS: Artemisinin based combination therapy,

Available at: www.searo.who.int/LinkFiles/Drug_Policy_
RBMInfosheet_9.pdf (Accessed on 2 March 2011).

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Watson L E, Bates P L, Evans T M, Unwin M M and Estes J

R, Molecular phylogeny of subtribe Artemisinae
(Asteraceae), including Artemisia and its allied and segregate
genera, BioMed Central Evolutionary Biology, 2 (17) (2002).

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Sharma V P, Artemisinin drug in the treatment of

Plasmodium falciparum malaria in India, Current Science, 90
(10) (2006) 1323-1324.

10. Wang Z, Qiu J, Guo T B, Liu A, Wang Y, Li Y and Zhang J

Z, Anti-inflammatory properties and regulatory mechanism
of a novel derivative of Artemisinin in experimental
autoimmune encephalomyelitis. Journal of Immunology
179(9) (2007) 5958-65.
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Extensible
Stylesheet
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map: Plasmodium falciparum endemicity in 2007. PLoS Med

6(2009) e1000048.
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14. http://whoindia.org/LinkFiles/Malaria_Country_ProfileMalaria.pdf (Accessed on 3 April 2011).

15. Google Scholar. http://scholar.google.co.in/ (Accessed on 22
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