Curriculum Framework

Principles of the Biomedical Sciences Unit 3 Lesson 3

Established
Goals

Desired Results (stage 1)

Transfer
Students will be able to independently use their learning to
T1 Explain how errors in the process of mitosis lead to chromosomal abnormalities, such as Trisomy 21 and Turner Syndrome.
Meaning
UNDERSTANDINGS: Students will understand that
ESSENTIAL QUESTIONS: Students will keep considering
U1 - Chromosomes transfer genetic material from cell to cell as
Q1 What are the differences between the processes and functions of
well as from generation to generation, in processes called mitosis
mitosis and meiosis?
and meiosis.
Q2 Why does sickle cell disease run in families yet is not expressed
in every generation?
U2 - There are often several forms of each gene, some being
dominant over the others.
Q3 Who has the right to decide how a persons tissues and organs
can be used?
U3 - There are many moral, ethical, and legal considerations
surrounding the right to a persons tissues and organs. (Optional)
Acquisition
KNOWLEDGE: Students will
SKILLS: Students will
K1 - Recognize that in order for cellular division to occur, exact
S1 - Demonstrate the processes of mitosis and meiosis. U1
copies of the DNA must be transferred to the resulting daughter
S2 - Model the inheritance of genetic diseases. U1, U2
cells. U1
S3 - Analyze genotype to determine phenotype. U2
K2 - Recognize that chromosomes in reproductive cells contain
S4 - Use proper techniques to examine, count, and measure
numerous genes that carry traits through the generations. U1, U2
chromosomes. U1 (Optional)
S5 - Appraise the rights a person has to the use of his or her tissues
and/or organs. U3 (Optional)

Project Lead The Way, Inc. Copyright 2013

Curriculum Framework PBS Unit 3 Lesson 3.3 Page 1
Format guided by: Wiggins, G. & McTighe, J. (2011). The understanding by design guide to creating high quality units. Alexandria. VA: ASCD

Evidence (stage 2)

Students will demonstrate knowledge

and skills by
Examining how genetic material is
passed from parents to offspring
(A3.3.1)
Students will

Assessments for
Learning

1. The teacher will

review the
students
results and give
feedback.

1. Distinguish between mitosis and

meiosis.
2. All
2. Determine the genotype and
assessments
phenotype of traits that are
will be
passed from parents to
reviewed.
offspring.
3. Build a concept map to illustrate
the process of inheriting of
traits.
1. Students
Investigating chromosomes (A3.3.2,
progress will be
Optional)
monitored and
Students will
each section
1. Conduct a cell spread
will be reviewed
experiment to determine the
before students
number of chromosomes.
move on.
2. Build a virtual karyotype to
visualize chromosomes
2. The teacher will
3. Analyze chromosomes for
review the
abnormalities
students

Assessments of
Learning

1. Students will record

their experimental
results

Activities (A), Projects

(P), and Problems (B)
A 3.3.1
A 3.3.2
A 3.3.3
A 3.3.4

Learning Plan (stage 3)

Knowledge and Skills
K1, K2, S1, S2, S3
S4
S5
K3, S5, S6

2. They will answer all

conclusion
questions.

1. Students will
record their
results.
2. They will
answer all the
conclusion
questions.

results and give

feedback.

Learning about the origin and ethics of

3. All the
conclusion will
be reviewed.
1. The teacher will

1. Students will

Project Lead The Way, Inc. Copyright 2013

Curriculum Framework PBS Unit 3 Lesson 3.3 Page 2
Format guided by: Wiggins, G. & McTighe, J. (2011). The understanding by design guide to creating high quality units. Alexandria. VA: ASCD

HeLa cells. (A3.3.3, Optional)

Students will

1. Read about the origin and

history of HeLa cells.
2. Discuss various medical ethics
scenarios.

review the
student
resource sheet
and give
feedback.
2. All
assessments
will be
reviewed.

complete the
Student resource
sheet.
2. They answer all
assessment
questions.

Project Lead The Way, Inc. Copyright 2013

Curriculum Framework PBS Unit 3 Lesson 3.3 Page 3
Format guided by: Wiggins, G. & McTighe, J. (2011). The understanding by design guide to creating high quality units. Alexandria. VA: ASCD