Paediatric Emergency Drug Doses

Drug

Notes

Dose

Newborn

Estimated Weight>>> 3kg

1months

3 months

6 months

1 year

3 years

5 years

10 years

4kg

5kg

8kg

10kg

15kg

18kg

30kg

Adenosine 6mg/2ml

dilute 2ml to 6ml gives 1mg/ml soln.

0.1mg/kg as a rapid bolus (0.1ml/kg)

0.3mg (ml)

0.4mg(ml)

0.5mg(ml)

0.8mg(ml)

1mg(ml)

1.5mg(ml)

1.8mg(ml)

3mg(ml)

Adrenaline 1:1000/ml

dilute 1ml to 10ml with WFI or NS

10mcg/kg, 0.1ml/kg

0.3ml

0.4ml

0.5ml

0.8ml

1ml

1.5ml

1.8ml

3ml

20mg

25mg

40mg

50mg

75mg

90mg

150mg

Amiodarone 150mg/3ml

give over 30-60 minutes, caution drops BP

5mg/kg, dilute in dextrose 5%

15mg

Atropine 0.6mg/ml

minimum dose is 100mcg, 0.17ml

0.02mg/kg

0.1mg (0.17ml) 0.1mg (0.17ml) 0.1mg (0.17ml) 0.15mg (0.25ml)0.2mg (0.35ml) 0.3mg (0.5ml) 0.36mg (0.6ml) 0.6mg (1ml)

Calcium Chloride 10%

use large or central vein

0.2ml/kg

0.6ml

0.8ml

1ml

1.6ml

2ml

3ml

3.6ml

6ml

Dextrose 50%

dilute to <25% with WFI

2ml/kg of 25%

6ml

8ml

10ml

16ml

20ml

30ml

36ml

60ml

3mg (0.6ml)

3.6mg (0.7ml) 6mg (1.2ml)

Diazepam 10mg/2ml

do not dilute

0.2mg/kg

0.6mg (0.12ml) 0.8mg (0.16ml) 1mg (0.2ml)

Etomidate 20mg/10ml

give slowly

0.3 mg/kg

0.9mg (0.45ml) 1.2mg (0.6ml) 1.5mg (0.8ml) 2.4mg (1.2ml) 3mg (1.5ml)

Flumazenil 0.5mg/5ml

may need repeated doses, total 1mg

5mcg/kg, max of 0.2mg

0.5-1mg/kg

20mcg (0.2ml) 20mcg (0.2ml) 30mcg (0.3ml) 40mcg (0.4ml) 50mcg (0.5ml) 80mcg (0.8ml) 90mcg (0.9ml) 150mcg (1.5ml)
3mg (0.3ml)

4mg (0.4ml)

5mg (0.5ml)

8mg (0.8ml)

10mg (1ml)

15mg (1.5ml)

18mg (1.8ml)

30mg (3ml)

Hydralazine 20mg

dilute 1ml to 20 ml, gives 1mg/ml soln.

0.1-0.2mg/kg

0.3mg(ml)

0.4mg(ml)

0.5mg(ml)

0.8mg(ml)

1mg(ml)

1.5mg(ml)

1.8mg(ml)

3mg(ml)

Hydrocortisone 100mg

dilute 100mg to 2 ml, gives 50mg/ml soln.

5mg/kg

15mg (0.3ml)

20mg (0.4ml)

25mg (0.5ml)

40mg (0.8ml)

50mg (1ml)

75mg (1.5ml)

90mg (1.8ml)

150mg (3ml)

3mg (0.3ml)

4mg (0.4ml)

5mg (0.5ml)

8mg (0.8ml)

10mg (1ml)

15mg (1.5ml)

18mg (1.8ml)

30mg (3.0ml)

Midazolam 15mg/3ml

maximum cumulative dose 0.5mg/kg

1mg/kg
0.1-0.2mg/kg

Sodium Bicarbonate

8.4%/20ml (1mmol/ml), give in central vein

1-2mmol/kg

Frusemide 20mg/2ml

Lignocaine 1% 10mg/ml

1.6mg (0.3ml) 2mg (0.4ml)

0.3mg (0.06ml) 0.4mg (0.08ml) 0.5mg (0.1ml) 0.8mg (0.16ml) 1mg (0.2ml)

4.5mg (2.3ml) 5.4mg (2.7ml) 9mg (4.5ml)

1.5mg (0.3ml) 1.8mg (0.36ml) 3mg (0.6ml)

3mmol(ml)

4mmol(ml)

5mmol(ml)

8mmol(ml)

10mmol(ml)

15mmol(ml)

18mmol(ml)

30mmol(ml)

or dilute with NS to 4.2% (0.5mmol/ml), safe in peripheral vein

6mls

8mls

10mls

16mls

20mls

30mls

36mls

60mls

Naloxone 0.4mg/ml

may need repeated doses

0.1mg/kg

0.3mg (0.8ml) 0.4mg (1ml)

0.5mg (1.3ml) 0.8mg (2ml)

1mg (2.5ml)

1.5mg (3.8ml) 1.8mg (4.5ml) 3mg (7.5ml)

Propranolol 1mg/ml

give slowly, <1mg/min

0.3 mg(ml)

0.4mg(ml)

0.5mg(ml)

0.8mg(ml)

1mg(ml)

1.5mg(ml)

1.8mg(ml)

3mg(ml)

Succinylcholine 50mg/ml

dilute 2ml to 10ml, gives 10mg/ml

0.1mg/kg
1-3mg/kg

3mg (0.3ml)

4mg (0.4ml)

5mg (0.5ml)

8mg (0.8ml)

10mg (1ml)

15mg (1.5ml)

18mg (1.8ml)

30mg (3ml)

Normal Saline or 5% Albumin, bolus for volume resuscitation

10-20ml/kg

60ml

80ml

100ml

160ml

200ml

300ml

360ml

600ml

Endotracheal Tube

size

3mm

3mm

3.5mm

4mm

4mm

4.5mm

5mm

6.5mm

length

9cm

10cm

10.5cm

11cm

12cm

13cm

14cm

17cm

Chest Tube

8F

8F

10F

10F

10F

14F

16F

20F

Urinary Catheter

5F

5F

8F

8F

8F

10F

12F

16F

2 joules/kg

6j

8j

10 j

16 j

20 j

30 j

36 j

60 j

4 joules/kg

12 j

16 j

20 j

32 j

40 j

60 j

72 j

120 j

Defibrillation
Defibrillation
Adrenaline

0.3mg/kg in 50ml NS, 1ml/hr=0.1mcg/kg/min, central vein, 0.05-2 mcg/kg/min

Dobutamine 250mg/5ml

30mg/kg in 50mls NS, 1ml/hr=10mcg/kg/min, give 0-20mcg/kg/min

Dopamine 200mg/5ml

30mg/kg in 50mls NS, 1ml/hr=10mcg/kg/min, give 0-20mcg/kg/min

Norepinephrine 4mg/4ml

0.3mg/kg in 50ml NS, 1ml/hr=0.1mcg/kg/min, give in central vein, 0.05-1 mcg/kg/min

Children's Intensive Care Unit

This sheet is intended for use in the emergency care of critically ill children, and is not a comprehensive guide to the drugs involved, please refer to a Paediatric Formulary for more information regarding side effects, cautions, contra-indications and
administration.
References: "Drug Doses" , F Shann, 12th edition; and "BNF for Children 2005", BMJ Publications.
Updated 4th June 2007 by Dr Janil Puthucheary
Children's Intensive Care Unit, KK Womens and Childrens Hospital, 2007
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