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What Is Librium?

What Are Therapeutic


Uses Of Librium?

Librium 10mg and Librium 25mg is commercially accessible in a


capsule dosage form. Librium has an amazing application in the
management of anxiety disorders. It also helps the people to get
relief from withdrawal symptoms occur after quitting of alcohol.
Librium is quite beneficial in reducing anxiety and fear before
undergoing surgery. Librium 10mg or Librium 25mg encloses an
active component called Chlordiazepoxide, which produces
calmness in the brain.

How does Librium work to alleviate


anxiety?
Chlordiazepoxide is an excellent member of the benzodiazepine
class of drugs. It binds to the benzodiazepine (BZD) binding sites
on GABA (A) receptors and augments the binding of GABA (an
inhibitory neurotransmitter to the GABA (A) receptors. It causes
causing neuronal membrane hyperpolarization by increasing the
GABA-mediated chloride influx. Overall, neuroinhibitory effects
cause reduction of overactivity of the brain and produce calmness
in the brain.

What is the dosing regimen of Librium


10mg or Librium 25mg?
Dose for the management of mild and moderate anxiety
disorders and symptoms of anxiety: A patient should
take 5mg or 10mg of Librium orally three to four times a
day.

Dose for the treatment of severe anxiety disorders and symptoms


of anxiety: A patient has to take 20mg or 25mg of Librium orally
three to four times a day.

The dose for preoperative apprehension and anxiety: On days


preceding surgery, 5 to 10 mg of Librium is taken orally, 3 or 4
times daily.

Dose for the relief of withdrawal symptoms of acute alcoholism:


Initially, an individual has to take 50 to 100 mg of Librium; the
dose of Librium is repeated until agitation is controlled and the
dose may enhance up to 300 mg per day.

What are the contraindications of


Librium?
An individual should not use Librium under these following medical conditions:

Myasthenia gravis
Acute intoxication with alcohol, narcotics, or other psychoactive
drugs

Ataxia
Severe hypoventilation
Acute narrow-angle glaucoma
Severe liver deficiencies
Severe sleep apnea
Hypersensitive reactions with Librium or its other
components

What are the safety measures that a person


has to follow while using Librium?
The use of Librium may cause dizziness or drowsiness, so do not drive or
perform any activities alertness.

Pregnant women and breastfeeding mothers should communicate with


their doctor before the use of Librium.
Intake of alcohol or sedative pills is strictly prohibited while using
Librium.

Librium should be used with extreme caution children, as the


safety and efficacy of Librium have not been established.
Do not suddenly stop taking Librium, as it may cause withdrawal
symptoms.

Therefore, reduce the dose of Librium over a week before


discontinuing it.
In case a person is facing any of these medical problems such
as breathing problems, kidney disease, liver disease, blood
disease, and drug or alcohol dependence, then he or she is
not allowed to take Librium without the permission of a
physician.

What are the undesired effects of


Librium?
A patient may experience some undesired effects while relying
on the treatment of Librium such as sleepiness,
lightheadedness, nausea, constipation, blurred vision,
headache, unusual weakness, and lack of coordination.

What are the possible drug interactions of


Librium?
Sodium Oxybate
Rifampin
Azole antifungals: Ketoconazole
Clozapine
Disulfiram
Nefazodone
Clozapine
Hydantoins: Phenytoin
Valproic acid
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